The online version of this article (doi:10.1186/1477-7819-10-265) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests.
Woda Shi and Yongfeng Shao drafted the manuscript. Woda Shi searched the papers and extracted the data. Wei Zhang and Haoliang Sun helped to extracted the data. All authors read and approved the final manuscript.
It is controversial that whether sleeve lobectomy (SL) should be promoted more worthy than pneumonectomy (PN) in suitable patients.
We searched all studies that had been published in English from PUBMED and Embase which compared the short-term and long-term outcomes of SL and pneumonectomy (PN) in patients with non-small cell lung cancer (NSCLC).
Nineteen studies met our criteria with a combined total of 3878 subjects, of which 1316 (33.9%) underwent SL and 2562 (66.1%) underwent PN. The odds ratio was 0.50 (95% CI: 0.34-0.72) for postoperative mortality, 1.17 (95% CI: 0.82-1.67) for postoperative complications, 0.78 (95% CI: 0.47-1.29) for locoregional recurrences. The risk difference for 1-, 3-, 5- year was 0.11 (95% CI: 0.07-0.14), 0.15 (95% CI: 0.06-0.24), 0.15 (95% CI: 0.09-0.20),respectively. The pooled hazard ratio was 0.63 (95% CI: 0.56-0.71) in favor of SL group.
SL is more worthy to be done than PN in suitable patients with less mortality and better long-term survival.
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- Sleeve lobectomy versus pneumonectomy for non-small cell lung cancer: a meta-analysis
- BioMed Central
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