To carry out the social study of living conditions we analysed reports of the National Institute of Statistics and Geography (INEGI) [
3], Ministry of Health (SESA) [
4] and the National Survey of Health and Nutrition (ENSANUT 2012) [
5], as well as citizen reports of access to health care in Oaxaca. Once the social data were obtained, health conditions were compared between the states ranked from 1 to 32, with the lowest and highest degrees of social vulnerability [
6] The ranking of the principal factors associated with diabetes and hypertension, living conditions and principal causes of mortality were obtained by dividing the rank occupied by the state by the total number of states (32) Mexico has 32 states, so the highest value implies the worst conditions. World Health Organization (WHO) [
7] reports and published scientific articles were consulted for biological studies associated with social conditions. Finally, the work data was analysed for morbidity and mortality related to living conditions in Oaxaca.
Health status of the Oaxaca population
The state of Oaxaca is located in the southeast of Mexico. It is divided into eight regions: the Isthmus, Mixteca, Sierra Sur, the Coast, Sierra Norte, Central Valleys, Tuxtepec or Papaloapan, and Cañada; furthermore, it is composed of 570 municipalities. The population in 2015 was 3,967,889, 2,079,211 women and 1,888,678 men [
3].
In 2013, life expectancy was 72.5 years, which is two years less than the national average; not only is life expectancy lower, a healthy life expectancy is 63.6 years in men and 67.7 years in women, which implies that at least five years of life will be unhealthy [
4].
The principal diseases vary by age; the National Survey of Health and Nutrition 2012 (ENSANUT by its initials in Spanish) states that the main causes of childhood morbidity are acute respiratory infections (ARI), followed by diarrheal diseases and urinary tract infections (UTI) [
5]. ARIs are presented as the most prevalent in adolescents but the prevalence is modified, as UTIs are listed in second place and diarrheal disease in third. Finally, coupled with these conditions, adulthood hypertension is reported to appear from the age of 20 and diabetes from 40, as shown in Table
1.
Table 1
Health status of Oaxaca
1 | Acute respiratory infections | Acute respiratory infections | Acute respiratory infections | Diabetes | Diabetes | Hyperglycaemia |
2 | Urinary tract infections | Intestinal infections by other organisms and some poorly defined | Intestinal infections by other organisms and some poorly defined | Ischemic heart | Ischemic heart | Bad dietary habits |
3 | Intestinal infections by other organisms and some poorly defined | Urinary tract infections | Urinary tract infections | Cerebrovascular diseases | Cirrhosis | Overweight and obesity |
4 | Gastric ulcers and duodenitis | Conjunctivitis | Gastric ulcers and duodenitis | Hypertensive disease | Homicides | Consumption of alcohol and drugs |
5 | Acute vulvovaginitis | Gastric ulcers and duodaenitis | Conjunctivitis | Malnutrition | Cerebrovascular diseases | Arterial hypertension |
6 | Conjunctivitis | Acute otitis media | Acute otitis media | Chronic respiratory diseases | Hypertensive disease | Low glomerular filtration |
7 | Acute otitis media | Gingivitis and periodontal diseases | Gingivitis and periodontal diseases | Cirrhosis | Traffic accidents | Malnutrition |
8 | Gingivitis and periodontal diseases | Intestinal amoebiasis | Acute vulvovaginitis | Acute respiratory infections | Chronic respiratory diseases | High cholesterol |
9 | Intestinal Amoebiasis | Febrile syndrome | Intestinal Amoebiasis | Renal insufficiency | Acute respiratory infections | Low physical activity |
10 | Febrile syndrome | Pharyngitis, streptococcal tonsillitis | Febrile syndrome | Congenital | Malnutrition | Smoking |
Ten of the previously mentioned diseases are responsible for years of lost healthy life in adults. Diabetes is the number one cause, followed by chronic kidney disease. These conditions highlight the evident economic impact, that despite having acceptable levels of education it has been observed that in different regions work absenteeism caused by illness increases vulnerability [
6].
Mortality
The first three causes of Oaxacan mortality noted in Table
1 are shared with the rest of the country, diabetes being the most significant, followed by ischemic and cerebrovascular diseases with a slightly different variation according to sex.
Amid the main causes of Oaxacan morbidity and mortality are some diseases where the state is at a significant disadvantage compared to others, such as Mexico City or Nuevo León, that have the lowest indexes of social vulnerability. For example, Oaxaca occupies different places in male and female mortality due to malnutrition. Malnutrition is the fifth leading cause of death in women and tenth in men, nevertheless, mortality due to malnutrition is nearly non-existent in Mexico City and Nuevo León [
8].
The principal illnesses in the states of Mexico with the highest and lowest social vulnerability reported by the Ministry of Health are displayed in Table
2. According to the level of health, the state of Oaxaca, compared to other states with lower vulnerability indexes, has the highest possible value (32) and, therefore, a lower degree of health.
Table 2
Illnesses in the states of the Mexican Republic with the highest and lowest social vulnerability
The table shows the ranking of the principal factors associated with diabetes and hypertension, living conditions and principal causes of mortality [
4].
Among the risk factors associated with mortality in the state are: hyperglycaemia, poor dietary habits, overweight and obesity, alcohol and drug consumption, hypertension, low glomerular filtration rate, malnutrition, high cholesterol, low physical activity and smoking [
4].
Housing
It is important to highlight that 65.9% of the population live in conditions of poverty, a situation that reflects the lack of basic services; it is also important to note that more than 20% of the population are without access to appropriate water sources, 31.2% are without access to sanitary services (disposal of excreta), 11% of the houses have dirt floors-an index markedly above the 3.2% national average- only 43.2% of the houses are built with a roof of resistant material and 11.6% of homes do not have water, electricity or gas, therefore occupying the penultimate place in the nation [
4,
10]. Furthermore, these conditions of poverty have a direct impact on health conditions, particularly water and indoor air pollution [
11,
12].
According to the World Health Organization (WHO) there are several diseases related to water caused by faecal-oral transmission of microorganisms and chemical substances present in drinking water [
7]. Diseases such as ascariasis, onchocerciasis, typhoid, schistosomiasis, campylobacter infection, cholera, diarrhoea and paratyphoid enteric fevers; these diseases are related to faecal-oral transmission by non-potable water. Parasitic diseases arise from a contaminated water source, which produces conditions such as diarrhoea that in conjunction with collateral risk factors generate various problems. The probability of parasitic illness is increased by consuming water from unsuitable groundwater tables or by drinking water that includes an intermediate mollusc, causing water-borne diseases such as schistosomiasis [
7,
11,
13‐
16].
However there are other diseases that have to do with the lack of access to water, such as malaria, where the transmission and reproduction of the
Aedes aegypti mosquito is related to water storage. Once the water has been collected, it must be stored, which increases the possibility of disease-bearing vectors, such as malaria, Zika virus and Chinkungunya, transmitted by
Aedes aegypti [
15‐
18] Villagers have a long walk to get clean water, and as a result, the same sanitary issues that concerned people in the early nineteenth century are still current in Oaxaca.
A fundamental feature of theses living conditions is that 49.5% of homes are saturated with polluted air, ranked as the last place in the country [
4]. This polluted air is generated by the use of solid fuels such as wood, agricultural waste, charcoal, coal and animal excrement for cooking and heating inside the home. [
12]
These fuels produce large amounts of particles such as soot, which penetrates deep into the lungs [
19,
20] moreover, if in addition homes are poorly ventilated with dirt floors, there is an increase of air pollutant particles, resulting in even more unfavourable living conditions.
Health issues arise from such exposure, and women and children are the most affected. It is well-known that being exposed to indoor air pollution almost doubles the risk of pneumonia during childhood and that more than half the deaths in children less than five years of age are caused by acute lower respiratory infection due to inhalation of indoor air contaminated by solid fuel [
12].
It is well known that particle-polluted air produces respiratory diseases, such as cancer, asthma and emphysema, and drastically increases the probability of suffering acute respiratory infections. In fact, WHO has estimated that one out of every three respiratory infections worldwid, is associated with exposure to polluted air [
12]. The results of inhaling particles generated by combustion, depending on the specific particle, are irritation, inflammation and hyper-reactivity; these particles reduce mucociliary and thus, macrophage response, they are also haemoglobin bound and thus reduce oxygen transport; the more bronchial reactivity, the more susceptibility to infections, even carcinogenic ones [
21]. The damage caused by this pollution is considered to be as alarming as tobacco smoke [
22].
While the respiratory effects of contaminated air inhalation is well known, WHO reports that of the 4.3 million people in the world who die prematurely due to inhaling polluted air, 12% is due to respiratory diseases, specifically pneumonia, while the rest are due to other conditions that are probably not related to that exposure; 34% cerebrovascular accidents, 26% ischemic heart disease, 22% chronic obstructive neuropathy, and 6% due to lung cancer. Contaminated air inhalation has even been associated with diabetes and preeclampsia [
23]. It is important to highlight that such conditions include three of the main causes of morbidity and mortality in Oaxaca.
Once pollutants enter the body through the respiratory tract producing chronic inflammation, pro-inflammatory cytokines are secreted, which triggers chronic inflammation and immunological responses. Once settled in the bloodstream these particles cause cardiovascular damage in various ways, such as the induction of oxidative stress, systemic inflammation, endothelial dysfunction, thrombosis that generates heart failure or ischemic diseases and arrhythmias. Additionally, accumulation of these contaminants in the arteries may form obstructions similar to those caused by high-fat diets [
24].
A large number of diseases prevalent in Oaxaca are associated with living conditions as shown in Table
3, such as limited access to suitable water sources, lack of access to sanitary services, a proper place for excreta disposal or exposure to polluted air.
Table 3
Diseases prevalent in Oaxaca associated with vulnerability factors
Access to suitable sources of water | Penultimate (31) | 80% | Ascariasis (helminthiasis), malaria, onchocerciasis, schistosomiasis, campylobacteriosis, diarrhoea typhoid, paratyphoid enteric fevers, anaemia, malnutrition. |
Houses with access to sanitary services | Last (32) | 66% |
Indoor polluted air exposure | Last (32) | 49.3% | Pneumonia, chronic obstructive pneumonia stroke, ischemic heart disease. |
Indoor usage of solid fuel | Last (32) | 49.3% |
Summary of the 20 leading causes of disease in the state of Oaxaca that, according to WHO, are related to the lack of appropriate water sources, lack of access to sanitary services and the use of solid fuel in the home.