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06.09.2022 | ANKLE

Socioeconomic deprivation status predicts both the incidence and nature of Achilles tendon rupture

verfasst von: J. F. Maempel, N. D. Clement, S. P. Mackenzie, C. McCann, T. O. White

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 2/2023

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Abstract

Purpose

The aim of this study was to describe the epidemiology of Achilles tendon rupture (ATR) and its relationship with socioeconomic deprivation status (SEDS). The hypothesis was that ATR occurs more frequently in socioeconomically deprived patients. Secondary aims were to determine variations in circumstances of injury between more and less deprived patients.

Methods

A 6-year retrospective review of consecutive patients presenting with ATR was undertaken. The health-board population was defined using governmental population data and SEDS was defined using the Scottish Index of Multiple Deprivation. The primary outcome was an epidemiological description and comparison of incidence in more and less deprived cohorts. Secondary outcomes included reporting of the relationship between SEDS and patient and injury characteristics with univariate and binary logistic regression analyses.

Results

There were 783 patients (567 male; 216 female) with ATR. Mean incidence for adults (≥ 18 years) was 18.75/100,000 per year (range 16.56–23.57) and for all ages was 15.26/100,000 per year (range 13.51 to 19.07). Incidence in the least deprived population quintiles (4th and 5th quintiles; 18.07 per 100,000/year) was higher than that in the most deprived quintiles (1st and 2nd; 11.32/100,000 per year; OR 1.60, 95%CI 1.35–1.89; p < 0.001).
When adjusting for confounding factors, least deprived patients were more likely to be > 50 years old (OR 1.97; 95%CI 1.24–3.12; p = 0.004), to sustain ATR playing sports (OR 1.72, 95%CI 1.11–2.67; p = 0.02) and in the spring (OR 1.65, 95%CI  1.01–2.70; p = 0.045) and to give a history of preceding tendinitis (OR  4.04, 95%CI 1.49–10.95; p = 0.006). They were less likely to sustain low-energy injuries (OR 0.44, 95%CI 0.23–0.87; p = 0.02) and to be obese (OR 0.25–0.41, 95%CI  0.07–0.90; p ≤ 0.03).

Conclusions

The incidence of ATR was higher in less socioeconomically deprived populations and the hypothesis was therefore rejected. Significant variations in patient and predisposing factors, mechanisms of injury and seasonality were demonstrated between most and least deprived groups, suggesting that circumstances and nature of ATR may vary with SEDS and these are not a homogenous group of injuries.

Level of Evidence

Prognostic Study Level III.
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Literatur
1.
Zurück zum Zitat Aujla RS, Patel S, Jones A, Bhatia M (2019) Non-operative functional treatment for acute Achilles tendon ruptures: The Leicester Achilles Management Protocol (LAMP). Injury 50(4):995–999CrossRef Aujla RS, Patel S, Jones A, Bhatia M (2019) Non-operative functional treatment for acute Achilles tendon ruptures: The Leicester Achilles Management Protocol (LAMP). Injury 50(4):995–999CrossRef
2.
Zurück zum Zitat Bedrick BS, Eskew AM, Chavarro JE, Jungheim ES (2020) Dietary patterns, physical activity, and socioeconomic associations in a midwestern cohort of healthy reproductive-age women. Matern Child Health J 24(10):1299–1307CrossRef Bedrick BS, Eskew AM, Chavarro JE, Jungheim ES (2020) Dietary patterns, physical activity, and socioeconomic associations in a midwestern cohort of healthy reproductive-age women. Matern Child Health J 24(10):1299–1307CrossRef
3.
Zurück zum Zitat Bengtsson C, Nordmark B, Klareskog L, Lundberg I, Alfredsson L (2005) Socioeconomic status and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study. Ann Rheum Dis 64(11):1588–1594CrossRef Bengtsson C, Nordmark B, Klareskog L, Lundberg I, Alfredsson L (2005) Socioeconomic status and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study. Ann Rheum Dis 64(11):1588–1594CrossRef
4.
Zurück zum Zitat Beynon C, Bailey L (2020) Prevalence of severe childhood obesity in Wales UK. J Public Health 42(4):e435–e439CrossRef Beynon C, Bailey L (2020) Prevalence of severe childhood obesity in Wales UK. J Public Health 42(4):e435–e439CrossRef
5.
Zurück zum Zitat Bostman OM (1995) Body-weight related to loss of reduction of fractures of the distal tibia and ankle. J Bone Joint Surg Br 77(1):101–103CrossRef Bostman OM (1995) Body-weight related to loss of reduction of fractures of the distal tibia and ankle. J Bone Joint Surg Br 77(1):101–103CrossRef
6.
Zurück zum Zitat Brodersen NH, Steptoe A, Boniface DR, Wardle J (2007) Trends in physical activity and sedentary behaviour in adolescence: ethnic and socioeconomic differences. Br J Sports Med 41(3):140–144CrossRef Brodersen NH, Steptoe A, Boniface DR, Wardle J (2007) Trends in physical activity and sedentary behaviour in adolescence: ethnic and socioeconomic differences. Br J Sports Med 41(3):140–144CrossRef
7.
Zurück zum Zitat Burrus MT, Werner BC, Park JS, Perumal V, Cooper MT (2016) Achilles tendon repair in obese patients is associated with increased complication rates. Foot Ankle Spec 9(3):208–214CrossRef Burrus MT, Werner BC, Park JS, Perumal V, Cooper MT (2016) Achilles tendon repair in obese patients is associated with increased complication rates. Foot Ankle Spec 9(3):208–214CrossRef
8.
Zurück zum Zitat Caldwell JE, Lightsey HM, Trofa DP, Swindell HW, Greisberg JK, Vosseller JT (2018) Seasonal Variation of Achilles Tendon Injury. J Am Acad Orthop Surg Glob Res Rev 2(8):e043 Caldwell JE, Lightsey HM, Trofa DP, Swindell HW, Greisberg JK, Vosseller JT (2018) Seasonal Variation of Achilles Tendon Injury. J Am Acad Orthop Surg Glob Res Rev 2(8):e043
9.
Zurück zum Zitat Cassell A, Edwards D, Harshfield A, Rhodes K, Brimicombe J, Payne R et al (2018) The epidemiology of multimorbidity in primary care: a retrospective cohort study. Br J Gen Pract 68(669):e245–e251CrossRef Cassell A, Edwards D, Harshfield A, Rhodes K, Brimicombe J, Payne R et al (2018) The epidemiology of multimorbidity in primary care: a retrospective cohort study. Br J Gen Pract 68(669):e245–e251CrossRef
10.
Zurück zum Zitat Chen C, Hunt KJ (2019) Open reconstructive strategies for chronic Achilles tendon ruptures. Foot Ankle Clin 24(3):425–437CrossRef Chen C, Hunt KJ (2019) Open reconstructive strategies for chronic Achilles tendon ruptures. Foot Ankle Clin 24(3):425–437CrossRef
11.
Zurück zum Zitat Clement ND, McQueen MM, Court-Brown CM (2014) Social deprivation influences the epidemiology and outcome of proximal humeral fractures in adults for a defined urban population of Scotland. Eur J Orthop Surg Traumatol 24(7):1039–1046CrossRef Clement ND, McQueen MM, Court-Brown CM (2014) Social deprivation influences the epidemiology and outcome of proximal humeral fractures in adults for a defined urban population of Scotland. Eur J Orthop Surg Traumatol 24(7):1039–1046CrossRef
12.
Zurück zum Zitat Concato J, Hartigan JA (2016) P values: from suggestion to superstition. J Investig Med 64(7):1166–1171CrossRef Concato J, Hartigan JA (2016) P values: from suggestion to superstition. J Investig Med 64(7):1166–1171CrossRef
14.
Zurück zum Zitat Cottom JM, Sisovsky CA (2021) Neglected Achilles tendon ruptures. Clin Podiatr Med Surg 38(2):261–277CrossRef Cottom JM, Sisovsky CA (2021) Neglected Achilles tendon ruptures. Clin Podiatr Med Surg 38(2):261–277CrossRef
15.
Zurück zum Zitat Court-Brown CM, Aitken SA, Duckworth AD, Clement ND, McQueen MM (2013) The relationship between social deprivation and the incidence of adult fractures. J Bone Joint Surg Am 95(6):e321–e327CrossRef Court-Brown CM, Aitken SA, Duckworth AD, Clement ND, McQueen MM (2013) The relationship between social deprivation and the incidence of adult fractures. J Bone Joint Surg Am 95(6):e321–e327CrossRef
16.
Zurück zum Zitat Ganestam A, Kallemose T, Troelsen A, Barfod KW (2015) Increasing incidence of acute Achilles tendon rupture and a noticeable decline in surgical treatment from 1994 to 2013 a nationwide registry study of 33,160 patients. Knee Surg Sports Traumatol Arthrosc 24(12):3730–3737CrossRef Ganestam A, Kallemose T, Troelsen A, Barfod KW (2015) Increasing incidence of acute Achilles tendon rupture and a noticeable decline in surgical treatment from 1994 to 2013 a nationwide registry study of 33,160 patients. Knee Surg Sports Traumatol Arthrosc 24(12):3730–3737CrossRef
17.
Zurück zum Zitat Hodgkins CW, Wessling NA (2021) Epidemiology of sports-specific foot and ankle injuries. Foot Ankle Clin 26(1):173–185CrossRef Hodgkins CW, Wessling NA (2021) Epidemiology of sports-specific foot and ankle injuries. Foot Ankle Clin 26(1):173–185CrossRef
18.
Zurück zum Zitat Hrotko J, Rueda-Sabater E, Lang N, Chin V (2019) Measure Well-Being to Improve It. The 2019 Sustainable Economic Development Assessment. Boston Consulting Group, Boston Hrotko J, Rueda-Sabater E, Lang N, Chin V (2019) Measure Well-Being to Improve It. The 2019 Sustainable Economic Development Assessment. Boston Consulting Group, Boston
19.
Zurück zum Zitat Huttunen TT, Kannus P, Rolf C, Fellander-Tsai L, Mattila VM (2014) Acute achilles tendon ruptures: incidence of injury and surgery in Sweden between 2001 and 2012. Am J Sports Med 42(10):2419–2423CrossRef Huttunen TT, Kannus P, Rolf C, Fellander-Tsai L, Mattila VM (2014) Acute achilles tendon ruptures: incidence of injury and surgery in Sweden between 2001 and 2012. Am J Sports Med 42(10):2419–2423CrossRef
20.
Zurück zum Zitat Jayanthi NA, Holt DB Jr, LaBella CR, Dugas LR (2018) Socioeconomic factors for sports specialization and injury in youth athletes sports. Health 10(4):303–310 Jayanthi NA, Holt DB Jr, LaBella CR, Dugas LR (2018) Socioeconomic factors for sports specialization and injury in youth athletes sports. Health 10(4):303–310
21.
Zurück zum Zitat Jenkins PJ, Watts AC, Duckworth AD, McEachan JE (2012) Socioeconomic deprivation and the epidemiology of carpal tunnel syndrome. J Hand Surg Eur 37(2):123–129CrossRef Jenkins PJ, Watts AC, Duckworth AD, McEachan JE (2012) Socioeconomic deprivation and the epidemiology of carpal tunnel syndrome. J Hand Surg Eur 37(2):123–129CrossRef
22.
Zurück zum Zitat Kamphuis CB, van Lenthe FJ, Giskes K, Huisman M, Brug J, Mackenbach JP (2008) Socioeconomic status, environmental and individual factors, and sports participation. Med Sci Sports Exerc 40(1):71–81CrossRef Kamphuis CB, van Lenthe FJ, Giskes K, Huisman M, Brug J, Mackenbach JP (2008) Socioeconomic status, environmental and individual factors, and sports participation. Med Sci Sports Exerc 40(1):71–81CrossRef
23.
Zurück zum Zitat Lemme NJ, Li NY, DeFroda SF, Kleiner J, Owens BD (2018) Epidemiology of Achilles tendon ruptures in the united states: athletic and nonathletic injuries from 2012 to 2016. Orthop J Sports Med 6(11):2325967118808238CrossRef Lemme NJ, Li NY, DeFroda SF, Kleiner J, Owens BD (2018) Epidemiology of Achilles tendon ruptures in the united states: athletic and nonathletic injuries from 2012 to 2016. Orthop J Sports Med 6(11):2325967118808238CrossRef
24.
Zurück zum Zitat Maempel JF, Clement ND, Wickramasinghe NR, Duckworth AD, Keating JF (2020) Operative repair of acute Achilles tendon rupture does not give superior patient-reported outcomes to nonoperative management. Bone Joint J 102-B(7):933–940CrossRef Maempel JF, Clement ND, Wickramasinghe NR, Duckworth AD, Keating JF (2020) Operative repair of acute Achilles tendon rupture does not give superior patient-reported outcomes to nonoperative management. Bone Joint J 102-B(7):933–940CrossRef
25.
Zurück zum Zitat Maempel JF, White TO, MacKenzie SP, McCann C, Clement ND (2022) The epidemiology of Achilles tendon re-rupture and associated risk factors: male gender, younger age and traditional immobilising rehabilitation are risk factors Knee Surg Sports. Traumatol Arthrosc 30(7):2457–2469CrossRef Maempel JF, White TO, MacKenzie SP, McCann C, Clement ND (2022) The epidemiology of Achilles tendon re-rupture and associated risk factors: male gender, younger age and traditional immobilising rehabilitation are risk factors Knee Surg Sports. Traumatol Arthrosc 30(7):2457–2469CrossRef
26.
Zurück zum Zitat Maffulli N, Waterston SW, Squair J, Reaper J, Douglas AS (1999) Changing incidence of Achilles tendon rupture in Scotland: a 15-year study. Clin J Sport Med 9(3):157–160CrossRef Maffulli N, Waterston SW, Squair J, Reaper J, Douglas AS (1999) Changing incidence of Achilles tendon rupture in Scotland: a 15-year study. Clin J Sport Med 9(3):157–160CrossRef
28.
Zurück zum Zitat Noback PC, Jang ES, Cuellar DO, Seetharaman M, Malagoli E, Greisberg JK et al (2017) Risk factors for achilles tendon rupture: a matched case control study. Injury 48(10):2342–2347CrossRef Noback PC, Jang ES, Cuellar DO, Seetharaman M, Malagoli E, Greisberg JK et al (2017) Risk factors for achilles tendon rupture: a matched case control study. Injury 48(10):2342–2347CrossRef
29.
Zurück zum Zitat Oliver WM, Mackenzie SA, Lenart L, McCann CJ, MacKenzie SP, Duckworth AD et al (2022) Age, personal and family history are independently associated with venous thromboembolism following acute Achilles tendon rupture. Injury 53(2):762–770CrossRef Oliver WM, Mackenzie SA, Lenart L, McCann CJ, MacKenzie SP, Duckworth AD et al (2022) Age, personal and family history are independently associated with venous thromboembolism following acute Achilles tendon rupture. Injury 53(2):762–770CrossRef
30.
Zurück zum Zitat Park HG, Youn D, Baik JM, Hwang JH (2021) Epidemiology of Achilles Tendon Rupture in South Korea: Claims Data of the National Health Insurance Service from 2009 to 2017. Clin Orthop Surg 13(4):539–548CrossRef Park HG, Youn D, Baik JM, Hwang JH (2021) Epidemiology of Achilles Tendon Rupture in South Korea: Claims Data of the National Health Insurance Service from 2009 to 2017. Clin Orthop Surg 13(4):539–548CrossRef
31.
Zurück zum Zitat Reyes C, Garcia-Gil M, Elorza JM, Mendez-Boo L, Hermosilla E, Javaid MK et al (2015) Socio-economic status and the risk of developing hand, hip or knee osteoarthritis: a region-wide ecological study. Osteoarthritis Cartilage 23(8):1323–1329CrossRef Reyes C, Garcia-Gil M, Elorza JM, Mendez-Boo L, Hermosilla E, Javaid MK et al (2015) Socio-economic status and the risk of developing hand, hip or knee osteoarthritis: a region-wide ecological study. Osteoarthritis Cartilage 23(8):1323–1329CrossRef
32.
Zurück zum Zitat Saarensilta IA, Edman G, Ackermann PW (2020) Achilles tendon ruptures during summer show the lowest incidence, but exhibit an increased risk of re-rupture. Knee Surg Sports Traumatol Arthrosc 28(12):3978–3986CrossRef Saarensilta IA, Edman G, Ackermann PW (2020) Achilles tendon ruptures during summer show the lowest incidence, but exhibit an increased risk of re-rupture. Knee Surg Sports Traumatol Arthrosc 28(12):3978–3986CrossRef
33.
Zurück zum Zitat Salonen MK, Kajantie E, Osmond C, Forsen T, Yliharsila H, Paile-Hyvarinen M et al (2009) Role of socioeconomic indicators on development of obesity from a life course perspective J Environ. Public Health 2009:625168 Salonen MK, Kajantie E, Osmond C, Forsen T, Yliharsila H, Paile-Hyvarinen M et al (2009) Role of socioeconomic indicators on development of obesity from a life course perspective J Environ. Public Health 2009:625168
35.
Zurück zum Zitat Seeger JD, West WA, Fife D, Noel GJ, Johnson LN, Walker AM (2006) Achilles tendon rupture and its association with fluoroquinolone antibiotics and other potential risk factors in a managed care population. Pharmacoepidemiol Drug Saf 15(11):784–792CrossRef Seeger JD, West WA, Fife D, Noel GJ, Johnson LN, Walker AM (2006) Achilles tendon rupture and its association with fluoroquinolone antibiotics and other potential risk factors in a managed care population. Pharmacoepidemiol Drug Saf 15(11):784–792CrossRef
36.
Zurück zum Zitat Sheth U, Wasserstein D, Jenkinson R, Moineddin R, Kreder H, Jaglal SB (2017) The epidemiology and trends in management of acute achilles tendon ruptures in Ontario, Canada: a population-based study of patients. Bone Joint J 99-B(1):78–86CrossRef Sheth U, Wasserstein D, Jenkinson R, Moineddin R, Kreder H, Jaglal SB (2017) The epidemiology and trends in management of acute achilles tendon ruptures in Ontario, Canada: a population-based study of patients. Bone Joint J 99-B(1):78–86CrossRef
37.
Zurück zum Zitat Steginsky BD, Van DB, Berlet GC (2017) The missed Achilles tear: now what? Foot Ankle Clin 22(4):715–734CrossRef Steginsky BD, Van DB, Berlet GC (2017) The missed Achilles tear: now what? Foot Ankle Clin 22(4):715–734CrossRef
38.
Zurück zum Zitat Suchak AA, Bostick G, Reid D, Blitz S, Jomha N (2005) The incidence of Achilles tendon ruptures in edmonton. Canada Foot Ankle Int 26(11):932–936CrossRef Suchak AA, Bostick G, Reid D, Blitz S, Jomha N (2005) The incidence of Achilles tendon ruptures in edmonton. Canada Foot Ankle Int 26(11):932–936CrossRef
39.
Zurück zum Zitat Svedman S, Edman G, Ackermann PW (2020) Deep venous thrombosis after Achilles tendon rupture is associated with poor patient-reported outcome. Knee Surg Sports Traumatol Arthrosc 28(10):3309–3317CrossRef Svedman S, Edman G, Ackermann PW (2020) Deep venous thrombosis after Achilles tendon rupture is associated with poor patient-reported outcome. Knee Surg Sports Traumatol Arthrosc 28(10):3309–3317CrossRef
40.
Zurück zum Zitat Tarantino D, Palermi S, Sirico F, Corrado B (2020) Achilles tendon rupture: mechanisms of injury principles of rehabilitation and return to play. J Funct Morphol Kinesiol 5(4):95CrossRef Tarantino D, Palermi S, Sirico F, Corrado B (2020) Achilles tendon rupture: mechanisms of injury principles of rehabilitation and return to play. J Funct Morphol Kinesiol 5(4):95CrossRef
41.
Zurück zum Zitat Urwin M, Symmons D, Allison T, Brammah T, Busby H, Roxby M et al (1998) Estimating the burden of musculoskeletal disorders in the community: the comparative prevalence of symptoms at different anatomical sites, and the relation to social deprivation. Ann Rheum Dis 57(11):649–655CrossRef Urwin M, Symmons D, Allison T, Brammah T, Busby H, Roxby M et al (1998) Estimating the burden of musculoskeletal disorders in the community: the comparative prevalence of symptoms at different anatomical sites, and the relation to social deprivation. Ann Rheum Dis 57(11):649–655CrossRef
42.
Zurück zum Zitat Valentin G, Ravn MB, Jensen EK, Friis K, Bhimjiyani A, Ben-Shlomo Y et al (2021) Socio-economic inequalities in fragility fracture incidence: a systematic review and meta-analysis of 61 observational studies. Osteoporos Int 32(12):2433–2448CrossRef Valentin G, Ravn MB, Jensen EK, Friis K, Bhimjiyani A, Ben-Shlomo Y et al (2021) Socio-economic inequalities in fragility fracture incidence: a systematic review and meta-analysis of 61 observational studies. Osteoporos Int 32(12):2433–2448CrossRef
43.
Zurück zum Zitat Varo JJ, Martinez-Gonzalez MA, De Irala-Estevez J, Kearney J, Gibney M, Martinez JA (2003) Distribution and determinants of sedentary lifestyles in the European Union. Int J Epidemiol 32(1):138–146CrossRef Varo JJ, Martinez-Gonzalez MA, De Irala-Estevez J, Kearney J, Gibney M, Martinez JA (2003) Distribution and determinants of sedentary lifestyles in the European Union. Int J Epidemiol 32(1):138–146CrossRef
44.
Zurück zum Zitat Westin O, Nilsson HK, Gravare SK, Samuelsson K, Brorsson A, Karlsson J (2018) Patients with an Achilles tendon re-rupture have long-term functional deficits and worse patient-reported outcome than primary ruptures. Knee Surg Sports Traumatol Arthrosc 26(10):3063–3072CrossRef Westin O, Nilsson HK, Gravare SK, Samuelsson K, Brorsson A, Karlsson J (2018) Patients with an Achilles tendon re-rupture have long-term functional deficits and worse patient-reported outcome than primary ruptures. Knee Surg Sports Traumatol Arthrosc 26(10):3063–3072CrossRef
Metadaten
Titel
Socioeconomic deprivation status predicts both the incidence and nature of Achilles tendon rupture
verfasst von
J. F. Maempel
N. D. Clement
S. P. Mackenzie
C. McCann
T. O. White
Publikationsdatum
06.09.2022
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 2/2023
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-022-07103-2

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