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01.12.2015 | Research article | Ausgabe 1/2015 Open Access

BMC Public Health 1/2015

Socioeconomic factors and other sources of variation in the prevalence of genital chlamydia infections: A systematic review and meta-analysis

Zeitschrift:
BMC Public Health > Ausgabe 1/2015
Autoren:
Joanna Crichton, Matthew Hickman, Rona Campbell, Harriet Batista-Ferrer, John Macleod
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​s12889-015-2069-7) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

JC, JM, MH and RC participated in the design of the study. JC designed and carried out the bibliographic database searches. JC and H B-F screened publications for eligibility and carried out data extraction. JM and MH advised on statistical analysis. JC performed the statistical analysis and drafted the paper. All authors provided feedback on drafts and read and approved the final manuscript.

Abstract

Background

The success of chlamydia screening programmes relies on their ability to effectively target those with greatest need. Young people from disadvantaged backgrounds may be at greater need for chlamydia screening, but existing evidence on the variation of prevalence with social position is inconclusive. We carried out a systematic review to examine variation in chlamydia prevalence in populations and possible sources of this variation.

Methods

Studies were eligible if they reported chlamydia prevalence derived from population-based samples that included young people aged 15–24 years from Europe, North America or Australia. Systematic searches of the following databases were undertaken from their inception to November 2014: MEDLINE, Embase, Web of Science and PsychINFO. There were no restrictions by language or publication date. Independent screening for eligibility and data extraction were carried out by two reviewers. Where possible, data were pooled in a meta-analysis using a random effects model. Heterogeneity was further investigated using meta-regression techniques.

Results

Of 1248 unique titles and abstracts and 263 potentially relevant full texts, 29 studies were eligible for inclusion. There was relatively strong evidence that disadvantaged young people had an increased risk of having a chlamydia infection across multiple measures of disadvantage, including lower educational attainment (OR 1.94, 95 % CI: 1.52 to 2.47), lower occupational class (OR 1.49, 95 % CI: 1.07 to 2.08) and residence in deprived areas (OR 1.76, 95 % CI: 1.15 to 2.71) with an overall OR of 1.66 (95 % CI: 1.37 to 2.02). Socioeconomic disadvantage was associated with chlamydia infection in both men and women. There was weaker evidence that prevalence estimates also varied by gender and age.

Conclusions

This review provides evidence of a consistent association between socioeconomic disadvantage and higher risk of Chlamydia infection. This association may reflect a number of factors including social variation in engagement with Chlamydia control programmes. Chlamydia screening could therefore reduce or increase health inequalities, depending on service provision and uptake by different socioeconomic groups.
Zusatzmaterial
Additional file 1: Search Strategy. (PDF 49 kb)
12889_2015_2069_MOESM1_ESM.pdf
Additional file 2: Characteristics of included studies, estimates of prevalence and available data on socioeconomic position. (DOCX 97 kb)
12889_2015_2069_MOESM2_ESM.docx
Additional file 3: Risk of bias and relevance assessments. (PDF 292 kb)
12889_2015_2069_MOESM3_ESM.pdf
Literatur
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