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Erschienen in: Endocrine 1/2018

20.02.2018 | Editorial

Somatostatin and diabetic retinopathy: an evolving story

verfasst von: Olga Simó-Servat, Cristina Hernández, Rafael Simó

Erschienen in: Endocrine | Ausgabe 1/2018

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Excerpt

The story of how somatostatin (SST) has come to play an evolving role in the treatment of diabetic retinopathy (DR) has to be seen in the context of the growth of scientific knowledge regarding the pathophysiology of DR. …
Literatur
2.
Zurück zum Zitat J.D. Poulsen, Diabetes and anterior pituitary deficiency: final course and postmortem study of a diabetic patient with Sheehan’s syndrome. Diabetes 15, 73–77 (1966)CrossRefPubMed J.D. Poulsen, Diabetes and anterior pituitary deficiency: final course and postmortem study of a diabetic patient with Sheehan’s syndrome. Diabetes 15, 73–77 (1966)CrossRefPubMed
3.
Zurück zum Zitat T.J. Merimee, S.E. Fineberg, V.A. McKusik, J. Hall, Diabetes mellitus and sexual ateliotic dwarfism: comparative study. J. Clin. Invest. 49(6), 1096–1102 (1970)CrossRefPubMedPubMedCentral T.J. Merimee, S.E. Fineberg, V.A. McKusik, J. Hall, Diabetes mellitus and sexual ateliotic dwarfism: comparative study. J. Clin. Invest. 49(6), 1096–1102 (1970)CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat P.S. Sharp, T.J. Fallon, O.J. Brazier, L. Sandler, G.F. Joplin, E.M. Kohner, Long term follow-up of patients who underwent ytrum-90 pituitary implantation for treatment of proliferative diabetic retinopathy. Diabetologia 30(4), 199–207 (1987)CrossRefPubMed P.S. Sharp, T.J. Fallon, O.J. Brazier, L. Sandler, G.F. Joplin, E.M. Kohner, Long term follow-up of patients who underwent ytrum-90 pituitary implantation for treatment of proliferative diabetic retinopathy. Diabetologia 30(4), 199–207 (1987)CrossRefPubMed
5.
Zurück zum Zitat E.M. Kohner, G.F. Joplin, R.K. Black, H. Cheng, T.R. Fraser, Pituitary ablation in the treatment of diabetic retinopathy. Trans. Ophthalmol. Soc. U.K. 92, 79–90 (1972)PubMed E.M. Kohner, G.F. Joplin, R.K. Black, H. Cheng, T.R. Fraser, Pituitary ablation in the treatment of diabetic retinopathy. Trans. Ophthalmol. Soc. U.K. 92, 79–90 (1972)PubMed
6.
Zurück zum Zitat M.B. Grant, R.N. Mames, C. Fitzgerald, K.M. Hazariwala, R. Cooper-DeHoff, S. Caballero, K.S. Estes, The efficacy of octreotide in the therapy of severe nonproliferative and early proliferative diabetic retinopathy: a randomized controlled study. Diabetes Care 23(4), 504–509 (2000)CrossRefPubMed M.B. Grant, R.N. Mames, C. Fitzgerald, K.M. Hazariwala, R. Cooper-DeHoff, S. Caballero, K.S. Estes, The efficacy of octreotide in the therapy of severe nonproliferative and early proliferative diabetic retinopathy: a randomized controlled study. Diabetes Care 23(4), 504–509 (2000)CrossRefPubMed
7.
Zurück zum Zitat B.O. Boehm, G.K. Lang, P.M. Jehle, B. Feldman, G.E. Lang, Octreotide reduces vitreous hemorrhage and loss of visual acuity risk in patients with high-risk proliferative diabetic retinopathy. Horm. Metab. Res. 33(5), 300–306 (2001)CrossRefPubMed B.O. Boehm, G.K. Lang, P.M. Jehle, B. Feldman, G.E. Lang, Octreotide reduces vitreous hemorrhage and loss of visual acuity risk in patients with high-risk proliferative diabetic retinopathy. Horm. Metab. Res. 33(5), 300–306 (2001)CrossRefPubMed
8.
Zurück zum Zitat S.S. Palii, S. Caballero, G. Shapiro, M.B. Grant, Medical treatment of diabetic retinopathy with somatostatin analogues. Expert Opin. Investig. Drugs 16(1), 73–82 (2007)CrossRefPubMed S.S. Palii, S. Caballero, G. Shapiro, M.B. Grant, Medical treatment of diabetic retinopathy with somatostatin analogues. Expert Opin. Investig. Drugs 16(1), 73–82 (2007)CrossRefPubMed
9.
Zurück zum Zitat R. Pivonello, G. Muscogiuri, G. Holder, M. Paul, S. Sarp, A. Lesogor, P. Jordaan, J. Eisinger, A. Colao, Long-term safety of long-acting octreotide in patients with diabetic retinopathy: results of pooled data from 2 randomized, double-blind, placebo-controlled phase 3 studies. Endocrine. https://doi.org/10.1007/s12020-017-1448-5. (2017) R. Pivonello, G. Muscogiuri, G. Holder, M. Paul, S. Sarp, A. Lesogor, P. Jordaan, J. Eisinger, A. Colao, Long-term safety of long-acting octreotide in patients with diabetic retinopathy: results of pooled data from 2 randomized, double-blind, placebo-controlled phase 3 studies. Endocrine. https://​doi.​org/​10.​1007/​s12020-017-1448-5. (2017)
10.
Zurück zum Zitat M. Takagi, T. Babazono, Y. Uchigata, Differences in risk factors for the onset of albuminuria and decrease in glomerular filtration in people with Type 2 diabetes mellitus: implications for the pathogenesis if diabetic kidney disease. Diabet. Med. 32(10), 1354–1360 (2015)CrossRefPubMedPubMedCentral M. Takagi, T. Babazono, Y. Uchigata, Differences in risk factors for the onset of albuminuria and decrease in glomerular filtration in people with Type 2 diabetes mellitus: implications for the pathogenesis if diabetic kidney disease. Diabet. Med. 32(10), 1354–1360 (2015)CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat J.R. Brownrigg, C.O. Hughes, D. Burleigh, A. Karthikesalingam, B.O. Patterson, P.J. Holt, M.M. Thompson, S. de Lusignan, K.K. Ray, R.J. Hinchliffe, Microvascular disease and risk of cardiovascular events among individuals with type 2 diabetes: a population-level cohort study. Lancet Diabetes Endocrinol. 4(7), 588–597 (2016)CrossRefPubMed J.R. Brownrigg, C.O. Hughes, D. Burleigh, A. Karthikesalingam, B.O. Patterson, P.J. Holt, M.M. Thompson, S. de Lusignan, K.K. Ray, R.J. Hinchliffe, Microvascular disease and risk of cardiovascular events among individuals with type 2 diabetes: a population-level cohort study. Lancet Diabetes Endocrinol. 4(7), 588–597 (2016)CrossRefPubMed
12.
Zurück zum Zitat J.F. Payne, V. Tangpricha, J. Cleveland, M.L. Lynn, R. Ray, S.K. Srivastava, Serum insulin-like growth factor-I in diabetic retinopathy. Mol. Vis. 17, 2318–1324 (2011)PubMedPubMedCentral J.F. Payne, V. Tangpricha, J. Cleveland, M.L. Lynn, R. Ray, S.K. Srivastava, Serum insulin-like growth factor-I in diabetic retinopathy. Mol. Vis. 17, 2318–1324 (2011)PubMedPubMedCentral
13.
Zurück zum Zitat Q. Wang, D. Dills, R. Klein, B. Klein, S. Moss, Does insulin-like growth factor I predict incidence and progression of diabetic retinopathy? Diabetes 44(2), 161–164 (1995)CrossRefPubMed Q. Wang, D. Dills, R. Klein, B. Klein, S. Moss, Does insulin-like growth factor I predict incidence and progression of diabetic retinopathy? Diabetes 44(2), 161–164 (1995)CrossRefPubMed
14.
Zurück zum Zitat Growth Hormone Antagonist for Proliferative Diabetic Retinopathy Study Group, The effect of a growth hormone receptor antagonist drug on proliferative diabetic retinopathy. Ophthalmology 108(12), 2266–2272 (2001)CrossRef Growth Hormone Antagonist for Proliferative Diabetic Retinopathy Study Group, The effect of a growth hormone receptor antagonist drug on proliferative diabetic retinopathy. Ophthalmology 108(12), 2266–2272 (2001)CrossRef
15.
Zurück zum Zitat S. Azzoug, F. Chentli, Diabetic retinopathy in acromegaly. Indian J. Endocr. Metab. 18(3), 407–409 (2014)CrossRef S. Azzoug, F. Chentli, Diabetic retinopathy in acromegaly. Indian J. Endocr. Metab. 18(3), 407–409 (2014)CrossRef
16.
Zurück zum Zitat R. Simó, E. Carrasco, M. García-Ramírez, C. Hernández, Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy. Curr. Diabes. Rev. 2(1), 71–98 (2006)CrossRef R. Simó, E. Carrasco, M. García-Ramírez, C. Hernández, Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy. Curr. Diabes. Rev. 2(1), 71–98 (2006)CrossRef
17.
Zurück zum Zitat C. Gerhardinger, K.D. McClure, G. Romeo, F. Podesta, M. Lorenzi, IGF-I mRNA and signaling in the diabetic retina. Diabetes 50(1), 175–183 (2001)CrossRefPubMed C. Gerhardinger, K.D. McClure, G. Romeo, F. Podesta, M. Lorenzi, IGF-I mRNA and signaling in the diabetic retina. Diabetes 50(1), 175–183 (2001)CrossRefPubMed
18.
Zurück zum Zitat C. Hernández, O. Simó-Servat, R. Simó, Somatostatin and diabetic retinopathy: current concepts and new therapeutic perspectives. Endocrine 46(2), 209–214 (2014)CrossRefPubMed C. Hernández, O. Simó-Servat, R. Simó, Somatostatin and diabetic retinopathy: current concepts and new therapeutic perspectives. Endocrine 46(2), 209–214 (2014)CrossRefPubMed
19.
Zurück zum Zitat E. Carrasco, C. Hernández, A. Miralles, P. Huget, J. Farres, R. Simó, Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegeneration. Diabetes Care 30(11), 2902–2908 (2007)CrossRefPubMed E. Carrasco, C. Hernández, A. Miralles, P. Huget, J. Farres, R. Simó, Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegeneration. Diabetes Care 30(11), 2902–2908 (2007)CrossRefPubMed
20.
Zurück zum Zitat C. Hernández, E. Carrasco, R. Casamitjana, R. Deulofeu, J. García-Arumí, R. Simó, Somatostatin molecular variants in the vitreous fluid: a comparative study between diabetic patients with proliferative diabetic retinopathy and non-diabetic control subjects. Diabetes Care 28(8), 1941–1947 (2005)CrossRefPubMed C. Hernández, E. Carrasco, R. Casamitjana, R. Deulofeu, J. García-Arumí, R. Simó, Somatostatin molecular variants in the vitreous fluid: a comparative study between diabetic patients with proliferative diabetic retinopathy and non-diabetic control subjects. Diabetes Care 28(8), 1941–1947 (2005)CrossRefPubMed
21.
Zurück zum Zitat C. Hernández, M. García-Ramírez, L. Corraliza, J. Fernández-Carneado, J. Farrera-Sinfreu, B. Ponsati, A. González-Rodríguez, A.M. Valverde, R. Simó, Topical administration of somatostatin prevents retinal neurodegeneration in experimental diabetes. Diabetes 62(7), 2569–2578 (2013)CrossRefPubMedPubMedCentral C. Hernández, M. García-Ramírez, L. Corraliza, J. Fernández-Carneado, J. Farrera-Sinfreu, B. Ponsati, A. González-Rodríguez, A.M. Valverde, R. Simó, Topical administration of somatostatin prevents retinal neurodegeneration in experimental diabetes. Diabetes 62(7), 2569–2578 (2013)CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat C. Hernández, P. Bogdanov, C. Solà-Adell, J. Sampedro, M. Valeri, X. Genís, O. Simó-Servat, M. García-Ramírez, R. Simó, Topical administration of DPP-IV inhibitors prevents retinal neurodegeneration in experimental diabetes. Diabetologia 60(11), 2285–2298 (2017)CrossRefPubMed C. Hernández, P. Bogdanov, C. Solà-Adell, J. Sampedro, M. Valeri, X. Genís, O. Simó-Servat, M. García-Ramírez, R. Simó, Topical administration of DPP-IV inhibitors prevents retinal neurodegeneration in experimental diabetes. Diabetologia 60(11), 2285–2298 (2017)CrossRefPubMed
23.
Zurück zum Zitat C. Hernández, P. Bogdanov, L. Corraliza, M. García-Ramírez, C. Solà-Adell, J.A. Arranz, A.I. Arroba, A.M. Valverde, R. Simó, Topical administration of GLP-1 receptor agonists prevents retinal neurodegeneration in experimental diabetes. Diabetes 65(1), 172–187 (2016)PubMed C. Hernández, P. Bogdanov, L. Corraliza, M. García-Ramírez, C. Solà-Adell, J.A. Arranz, A.I. Arroba, A.M. Valverde, R. Simó, Topical administration of GLP-1 receptor agonists prevents retinal neurodegeneration in experimental diabetes. Diabetes 65(1), 172–187 (2016)PubMed
24.
Zurück zum Zitat A.R. Santos, L. Ribeiro, F. Bandello, R. Lattanzio, C. Egan, U. Frydkjaer-Olsen, J. García-Arumí, J. Gibson, J. Grauslund, S.P. Harding, G.E. Lang, P. Massin, E. Midena, P. Scanlon, S.J. Aldington, S. Simão, C. Schwartz, B. Ponsati, M. Porta, M.A. Costa, C. Hernández, J. Cunha-Vaz, R. Simó, European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR), Functional and Structural Findings of Neurodegeneration in Early Stages of Diabetic Retinopathy: Cross-sectional Analyses of Baseline Data of the EUROCONDOR Project. Diabetes 66(9), 2503–2510 (2017)CrossRefPubMed A.R. Santos, L. Ribeiro, F. Bandello, R. Lattanzio, C. Egan, U. Frydkjaer-Olsen, J. García-Arumí, J. Gibson, J. Grauslund, S.P. Harding, G.E. Lang, P. Massin, E. Midena, P. Scanlon, S.J. Aldington, S. Simão, C. Schwartz, B. Ponsati, M. Porta, M.A. Costa, C. Hernández, J. Cunha-Vaz, R. Simó, European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR), Functional and Structural Findings of Neurodegeneration in Early Stages of Diabetic Retinopathy: Cross-sectional Analyses of Baseline Data of the EUROCONDOR Project. Diabetes 66(9), 2503–2510 (2017)CrossRefPubMed
25.
Zurück zum Zitat R. Simó, F. Bandello, C. Egan, J. García-Arumí, J. Gibson, J. Grauslund, S.P. Harding, G.E. Lang, P. Massin, E. Midena, P. Scanlon, B. Ponsati, M. Porta, L. Ribeiro, C. Hernández, J. Cunha-Vaz, The European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR). Topical administration of somatostatin and brimonidine in the early stages of diabetic retinopathy: results of the EUROCONDOR study. Diabetologia 60(Suppl 1), 1 (2017). https://doi.org/10.1007/s00125-017-4350-z R. Simó, F. Bandello, C. Egan, J. García-Arumí, J. Gibson, J. Grauslund, S.P. Harding, G.E. Lang, P. Massin, E. Midena, P. Scanlon, B. Ponsati, M. Porta, L. Ribeiro, C. Hernández, J. Cunha-Vaz, The European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR). Topical administration of somatostatin and brimonidine in the early stages of diabetic retinopathy: results of the EUROCONDOR study. Diabetologia 60(Suppl 1), 1 (2017). https://​doi.​org/​10.​1007/​s00125-017-4350-z
26.
Zurück zum Zitat M. Trento, O. Durando, S. Lavecchia, L. Charrier, F. Cavallo, M.A. Costa, C. Hernández, R. Simó, M. Porta, EUROCONDOR trial investigators, Vision related quality of life in patients with type 2 diabetes in the EUROCONDOR trial. Endocrine 57(1), 83–88 (2017)CrossRefPubMed M. Trento, O. Durando, S. Lavecchia, L. Charrier, F. Cavallo, M.A. Costa, C. Hernández, R. Simó, M. Porta, EUROCONDOR trial investigators, Vision related quality of life in patients with type 2 diabetes in the EUROCONDOR trial. Endocrine 57(1), 83–88 (2017)CrossRefPubMed
Metadaten
Titel
Somatostatin and diabetic retinopathy: an evolving story
verfasst von
Olga Simó-Servat
Cristina Hernández
Rafael Simó
Publikationsdatum
20.02.2018
Verlag
Springer US
Erschienen in
Endocrine / Ausgabe 1/2018
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-018-1561-0

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