Skip to main content
main-content

16.11.2016 | Retinal Disorders | Ausgabe 4/2017

Graefe's Archive for Clinical and Experimental Ophthalmology 4/2017

Spectral-domain optical coherence tomography findings in idiopathic lamellar macular hole

Zeitschrift:
Graefe's Archive for Clinical and Experimental Ophthalmology > Ausgabe 4/2017
Autoren:
Elena Zampedri, Federica Romanelli, Francesco Semeraro, Barbara Parolini, Rino Frisina

Abstract

Background

To evaluate demographic, functional, and morphological parameters of idiopathic lamellar macular hole (ILMH).

Methods

Observational longitudinal retrospective study.
Optical coherence tomography examinations and corresponding clinical charts of a series of consecutive patients affected by ILMH, between January 2010 and March 2015, from the database of the Department of Ophthalmology of Trento Hospital, Italy, have been collected and examined.
Demographic and functional parameters were: age (year), gender (male/female), eye (right/left), lens status, best-corrected visual acuity (BCVA) in logarithm of the minimum angle of resolution (LogMAR).
Tomographic parameters were: LMH shape pattern (intraretinal splitting LMH, IR split LMH, and V-shaped LMH, V LMH), posterior vitreous detachment (PVD yes/ PVD no), ERM type (conventional ERM and atypical ERM), integrity of ellipsoid zone (EZ) and external limiting membrane (ELM), residual foveal thickness (RFT) micron (μ), maximal diameter of intraretinal splitting (MDIRS) (μ).

Results

One hundred and eighty-nine eyes of 175 patients were included. The mean age was 72.84 ± 9.6, range 41–96 years. BCVA mean was 0.24 ± 0.25, range 0 –1.3 LogMAR. One hundred and forty-one eyes (74.6 %) were affected by IR split LMH, 48 eyes (25.4 %) were affected by V LMH. Every cases of ILMH were associated with ERM: 117 (61.9 %) conventional ERM, 72 (38.1 %) atypical ERM. A significant prevalence of female gender, phakic condition, and PVD in conventional ERM ILMH subgroup (P = 0.000) was found. BCVA mean was better in the conventional ERM ILMH subgroup (P = 0.000). An association between the interruption of the outer retinal layers (EZ and ELM) and atypical ERM ILMH subgroup was highlighted (P = 0.000). The statistical analysis showed a correlation between BCVA and integrity of ELM (P = 0.000). RFT significantly decreased in atypical ERM ILMH subgroup at 24 months compared to time point 0 (P = 0.027). A progressive increase of MDIRS in both subgroups at 12 months and in atypical ERM ILMH subgroup at 24 months (P = 0.007) was highlighted.

Conclusions

This study demonstrated that ILMH was not a stable condition, showing morphological changes and an involvement of the outer retinal layers during the 2 years of follow-up.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 4/2017

Graefe's Archive for Clinical and Experimental Ophthalmology 4/2017 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

07.09.2018 | Video plus | Ausgabe 11/2018

Einseitige kombinierte Augenmuskeloperation zur Korrektur der Esotropie

Videobeitrag zur Rücklagerung des M. rectus medialis und Faltung des M. rectus lateralis

24.08.2018 | Leitlinien, Stellungnahmen und Empfehlungen | Ausgabe 10/2018

Stellungnahme von BVA, DOG und RG zur intravitrealen Therapie des visusmindernden Makulaödems bei retinalem Venenverschluss

Therapeutische Strategien, Stand 24.04.2018

20.08.2018 | Rehabilitation | CME | Ausgabe 10/2018 Open Access

Aktuelle Möglichkeiten der visuellen Rehabilitation

17.08.2018 | Das therapeutische und diagnostische Prinzip | Ausgabe 11/2018

Suprachoroidale Hydrogelplombe