Ausgabe 2/2018
Inhalt (12 Artikel)
Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience
David Capper, Damian Stichel, Felix Sahm, David T. W. Jones, Daniel Schrimpf, Martin Sill, Simone Schmid, Volker Hovestadt, David E. Reuss, Christian Koelsche, Annekathrin Reinhardt, Annika K. Wefers, Kristin Huang, Philipp Sievers, Azadeh Ebrahimi, Anne Schöler, Daniel Teichmann, Arend Koch, Daniel Hänggi, Andreas Unterberg, Michael Platten, Wolfgang Wick, Olaf Witt, Till Milde, Andrey Korshunov, Stefan M. Pfister, Andreas von Deimling
Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas
Kristian W. Pajtler, Ji Wen, Martin Sill, Tong Lin, Wilda Orisme, Bo Tang, Jens-Martin Hübner, Vijay Ramaswamy, Sujuan Jia, James D. Dalton, Kelly Haupfear, Hazel A. Rogers, Chandanamali Punchihewa, Ryan Lee, John Easton, Gang Wu, Timothy A. Ritzmann, Rebecca Chapman, Lukas Chavez, Fredrick A. Boop, Paul Klimo, Noah D. Sabin, Robert Ogg, Stephen C. Mack, Brian D. Freibaum, Hong Joo Kim, Hendrik Witt, David T. W. Jones, Baohan Vo, Amar Gajjar, Stan Pounds, Arzu Onar-Thomas, Martine F. Roussel, Jinghui Zhang, J. Paul Taylor, Thomas E. Merchant, Richard Grundy, Ruth G. Tatevossian, Michael D. Taylor, Stefan M. Pfister, Andrey Korshunov, Marcel Kool, David W. Ellison
Heterogeneity within the PF-EPN-B ependymoma subgroup
Florence M. G. Cavalli, Jens-Martin Hübner, Tanvi Sharma, Betty Luu, Martin Sill, Michal Zapotocky, Stephen C. Mack, Hendrik Witt, Tong Lin, David J. H. Shih, Ben Ho, Mariarita Santi, Lyndsey Emery, Juliette Hukin, Christopher Dunham, Roger E. McLendon, Eric S. Lipp, Sridharan Gururangan, Andrew Grossbach, Pim French, Johan M. Kros, Marie-Lise C. van Veelen, Amulya A. Nageswara Rao, Caterina Giannini, Sarah Leary, Shin Jung, Claudia C. Faria, Jaume Mora, Ulrich Schüller, Marta M. Alonso, Jennifer A. Chan, Almos Klekner, Lola B. Chambless, Eugene I. Hwang, Maura Massimino, Charles G. Eberhart, Matthias A. Karajannis, Benjamin Lu, Linda M. Liau, Massimo Zollo, Veronica Ferrucci, Carlos Carlotti, Daniela P. C. Tirapelli, Uri Tabori, Eric Bouffet, Marina Ryzhova, David W. Ellison, Thomas E. Merchant, Mark R. Gilbert, Terri S. Armstrong, Andrey Korshunov, Stefan M. Pfister, Michael D. Taylor, Kenneth Aldape, Kristian W. Pajtler, Marcel Kool, Vijay Ramaswamy
Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features
Maximilian Y. Deng, Martin Sill, Jason Chiang, Jens Schittenhelm, Martin Ebinger, Martin U. Schuhmann, Camelia-Maria Monoranu, Till Milde, Andrea Wittmann, Christian Hartmann, Clemens Sommer, Werner Paulus, Jutta Gärtner, Wolfgang Brück, Thomas Rüdiger, Alfred Leipold, Zane Jaunmuktane, Sebastian Brandner, Felice Giangaspero, Paolo Nozza, Jaume Mora, Andres Morales la Madrid, Ofelia Cruz Martinez, Jordan R. Hansford, Torsten Pietsch, Anna Tietze, Pablo Hernáiz-Driever, Iris Stoler, David Capper, Andrey Korshunov, David W. Ellison, Andreas von Deimling, Stefan M. Pfister, Felix Sahm, David T. W. Jones
DNA methylation-based reclassification of olfactory neuroblastoma
David Capper, Nils W. Engel, Damian Stichel, Matt Lechner, Stefanie Glöss, Simone Schmid, Christian Koelsche, Daniel Schrimpf, Judith Niesen, Annika K. Wefers, David T. W. Jones, Martin Sill, Oliver Weigert, Keith L. Ligon, Adriana Olar, Arend Koch, Martin Forster, Sebastian Moran, Oscar M. Tirado, Miguel Sáinz-Jaspeado, Jaume Mora, Manel Esteller, Javier Alonso, Xavier Garcia del Muro, Werner Paulus, Jörg Felsberg, Guido Reifenberger, Markus Glatzel, Stephan Frank, Camelia M. Monoranu, Valerie J. Lund, Andreas von Deimling, Stefan Pfister, Rolf Buslei, Julika Ribbat-Idel, Sven Perner, Volker Gudziol, Matthias Meinhardt, Ulrich Schüller
Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations
Annekathrin Reinhardt, Damian Stichel, Daniel Schrimpf, Felix Sahm, Andrey Korshunov, David E. Reuss, Christian Koelsche, Kristin Huang, Annika K. Wefers, Volker Hovestadt, Martin Sill, Dorothee Gramatzki, Joerg Felsberg, Guido Reifenberger, Arend Koch, Ulrich-W. Thomale, Albert Becker, Volkmar H. Hans, Marco Prinz, Ori Staszewski, Till Acker, Hildegard Dohmen, Christian Hartmann, Wolf Mueller, Muin S. A. Tuffaha, Werner Paulus, Katharina Heß, Benjamin Brokinkel, Jens Schittenhelm, Camelia-Maria Monoranu, Almuth Friederike Kessler, Mario Loehr, Rolf Buslei, Martina Deckert, Christian Mawrin, Patricia Kohlhof, Ekkehard Hewer, Adriana Olar, Fausto J. Rodriguez, Caterina Giannini, Amulya A. NageswaraRao, Uri Tabori, Nuno Miguel Nunes, Michael Weller, Ute Pohl, Zane Jaunmuktane, Sebastian Brandner, Andreas Unterberg, Daniel Hänggi, Michael Platten, Stefan M. Pfister, Wolfgang Wick, Christel Herold-Mende, David T. W. Jones, Andreas von Deimling, David Capper
FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma
Philipp Sievers, Damian Stichel, Daniel Schrimpf, Felix Sahm, Christian Koelsche, David E. Reuss, Annika K. Wefers, Annekathrin Reinhardt, Kristin Huang, Azadeh Ebrahimi, Yanghao Hou, Kristian W. Pajtler, Stefan M. Pfister, Martin Hasselblatt, Walter Stummer, Uta Schick, Christian Hartmann, Christian Hagel, Ori Staszewski, Guido Reifenberger, Rudi Beschorner, Roland Coras, Kathy Keyvani, Patricia Kohlhof, Francesca Diomedi-Camassei, Christel Herold-Mende, Felice Giangaspero, Elisabeth Rushing, Caterina Giannini, Andrey Korshunov, David T. W. Jones, Andreas von Deimling
Molecular characterization of medulloblastomas with extensive nodularity (MBEN)
Andrey Korshunov, Felix Sahm, Damian Stichel, Daniel Schrimpf, Marina Ryzhova, Olga Zheludkova, Andrey Golanov, Peter Lichter, David T. W. Jones, Andreas von Deimling, Stefan M. Pfister, Marcel Kool
Malignant rhabdoid tumors originating within and outside the central nervous system are clinically and molecularly heterogeneous
Emilia M. Pinto, Dima Hamideh, Armita Bahrami, Brent A. Orr, Tong Lin, Stanley Pounds, Gerard P. Zambetti, Alberto S. Pappo, Amar Gajjar, Sameer Agnihotri, Alberto Broniscer
Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations
Christian Koelsche, Martin Mynarek, Daniel Schrimpf, Luca Bertero, Jonathan Serrano, Felix Sahm, David E. Reuss, Yanghao Hou, Daniel Baumhoer, Christian Vokuhl, Uta Flucke, Iver Petersen, Wolfgang Brück, Stefan Rutkowski, Sandro Casavilca Zambrano, Juan Luis Garcia Leon, Rosdali Yesenia Diaz Coronado, Manfred Gessler, Oscar M. Tirado, Jaume Mora, Javier Alonso, Xavier Garcia del Muro, Manel Esteller, Dominik Sturm, Jonas Ecker, Till Milde, Stefan M. Pfister, Andrey Korshunov, Matija Snuderl, Gunhild Mechtersheimer, Ulrich Schüller, David T. W. Jones, Andreas von Deimling
Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile
David A. Solomon, Andrey Korshunov, Martin Sill, David T. W. Jones, Marcel Kool, Stefan M. Pfister, Xuemo Fan, Serguei Bannykh, Jethro Hu, Moise Danielpour, Rong Li, James Johnston, Elaine Cham, Tabitha Cooney, Peter P. Sun, Nancy Ann Oberheim Bush, Michael McDermott, Jessica Van Ziffle, Courtney Onodera, James P. Grenert, Boris C. Bastian, Javier E. Villanueva-Meyer, Melike Pekmezci, Andrew W. Bollen, Arie Perry