Ausgabe 2/2019
Alzheimer's disease risk genes: a close-up view (Pages: 171 - 236)
Inhalt (13 Artikel)
Novel Alzheimer’s disease risk genes: exhaustive investigation is paramount
Kristel Sleegers, Christine Van Broeckhoven
SORL1 genetic variants and Alzheimer disease risk: a literature review and meta-analysis of sequencing data
Dominique Campion, Camille Charbonnier, Gaël Nicolas
Evaluation of CD33 as a genetic risk factor for Alzheimer’s disease
Steven Estus, Benjamin C. Shaw, Nicholas Devanney, Yuriko Katsumata, Eileen E. Press, David W. Fardo
The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomics
Arne De Roeck, Christine Van Broeckhoven, Kristel Sleegers
The new genetic landscape of Alzheimer’s disease: from amyloid cascade to genetically driven synaptic failure hypothesis?
Pierre Dourlen, Devrim Kilinc, Nicolas Malmanche, Julien Chapuis, Jean-Charles Lambert
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity
Sven J. van der Lee, Olivia J. Conway, Iris Jansen, Minerva M. Carrasquillo, Luca Kleineidam, Erik van den Akker, Isabel Hernández, Kristel R. van Eijk, Najada Stringa, Jason A. Chen, Anna Zettergren, Till F. M. Andlauer, Monica Diez-Fairen, Javier Simon-Sanchez, Alberto Lleó, Henrik Zetterberg, Marianne Nygaard, Cornelis Blauwendraat, Jeanne E. Savage, Jonas Mengel-From, Sonia Moreno-Grau, Michael Wagner, Juan Fortea, Michael J. Keogh, Kaj Blennow, Ingmar Skoog, Manuel A. Friese, Olga Pletnikova, Miren Zulaica, Carmen Lage, Itziar de Rojas, Steffi Riedel-Heller, Ignacio Illán-Gala, Wei Wei, Bernard Jeune, Adelina Orellana, Florian Then Bergh, Xue Wang, Marc Hulsman, Nina Beker, Niccolo Tesi, Christopher M. Morris, Begoña Indakoetxea, Lyduine E. Collij, Martin Scherer, Estrella Morenas-Rodríguez, James W. Ironside, Bart N. M. van Berckel, Daniel Alcolea, Heinz Wiendl, Samantha L. Strickland, Pau Pastor, Eloy Rodríguez Rodríguez, Bradley F. Boeve, Ronald C. Petersen, Tanis J. Ferman, Jay A. van Gerpen, Marcel J. T. Reinders, Ryan J. Uitti, Lluís Tárraga, Wolfgang Maier, Oriol Dols-Icardo, Amit Kawalia, Maria Carolina Dalmasso, Mercè Boada, Uwe K. Zettl, Natasja M. van Schoor, Marian Beekman, Mariet Allen, Eliezer Masliah, Adolfo López de Munain, Alexander Pantelyat, Zbigniew K. Wszolek, Owen A. Ross, Dennis W. Dickson, Neill R. Graff-Radford, David Knopman, Rosa Rademakers, Afina W. Lemstra, Yolande A. L. Pijnenburg, Philip Scheltens, Thomas Gasser, Patrick F Chinnery, Bernhard Hemmer, Martijn A. Huisman, Juan Troncoso, Fermin Moreno, Ellen A. Nohr, Thorkild I. A. Sørensen, Peter Heutink, Pascual Sánchez-Juan, Danielle Posthuma, G. Coppola, A. M. Karydas, A. Varpetian, T. M. Foroud, A. I. Levey, W. A. Kukull, M. F. Mendez, J. Ringman, H. Chui, C. Cotman, C. DeCarli, B. L. Miller, D. H. Geschwind, Jordi Clarimón, Kaare Christensen, Nilüfer Ertekin-Taner, Sonja W. Scholz, Alfredo Ramirez, Agustín Ruiz, Eline Slagboom, Wiesje M. van der Flier, Henne Holstege
Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
Antonio Boza-Serrano, Rocío Ruiz, Raquel Sanchez-Varo, Juan García-Revilla, Yiyi Yang, Itzia Jimenez-Ferrer, Agnes Paulus, Malin Wennström, Anna Vilalta, David Allendorf, Jose Carlos Davila, John Stegmayr, Sebastian Jiménez, Maria A. Roca-Ceballos, Victoria Navarro-Garrido, Maria Swanberg, Christine L. Hsieh, Luis M. Real, Elisabet Englund, Sara Linse, Hakon Leffler, Ulf J. Nilsson, Guy C. Brown, Antonia Gutierrez, Javier Vitorica, Jose Luis Venero, Tomas Deierborg
RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas
Peter Wirthschaft, Julia Bode, Himanshu Soni, Fabio Dietrich, Thomas Krüwel, Bernd Fischer, Christiane B. Knobbe-Thomsen, Giulia Rossetti, Andreas Hentschel, Norman Mack, Kai Schönig, Michael O. Breckwoldt, André Schmandke, Stefan Pusch, Jan Medenbach, Martin Bendszus, Martin E. Schwab, Andreas von Deimling, Marcel Kool, Christel Herold-Mende, Guido Reifenberger, Robert Ahrends, Björn Tews
Mutational patterns and regulatory networks in epigenetic subgroups of meningioma
Nagarajan Paramasivam, Daniel Hübschmann, Umut H Toprak, Naveed Ishaque, Marian Neidert, Daniel Schrimpf, Damian Stichel, David Reuss, Philipp Sievers, Annekathrin Reinhardt, Annika K. Wefers, David T. W. Jones, Zuguang Gu, Johannes Werner, Sebastian Uhrig, Hans-Georg Wirsching, Matthias Schick, Melanie Bewerunge-Hudler, Katja Beck, Stephanie Brehmer, Steffi Urbschat, Marcel Seiz-Rosenhagen, Daniel Hänggi, Christel Herold-Mende, Ralf Ketter, Roland Eils, Zvi Ram, Stefan M. Pfister, Wolfgang Wick, Michael Weller, Rachel Grossmann, Andreas von Deimling, Matthias Schlesner, Felix Sahm
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes
Tanvi Sharma, Edward C. Schwalbe, Daniel Williamson, Martin Sill, Volker Hovestadt, Martin Mynarek, Stefan Rutkowski, Giles W. Robinson, Amar Gajjar, Florence Cavalli, Vijay Ramaswamy, Michael D. Taylor, Janet C. Lindsey, Rebecca M. Hill, Natalie Jäger, Andrey Korshunov, Debbie Hicks, Simon Bailey, Marcel Kool, Lukas Chavez, Paul A. Northcott, Stefan M. Pfister, Steven C. Clifford
Molecular progression of SHH-activated medulloblastomas
Andrey Korshunov, Konstantin Okonechnikov, Felix Sahm, Marina Ryzhova, Damian Stichel, Philipp Sievers, Jochen Meyer, Daniel Schrimpf, Olga Zheludkova, Andrey Golanov, Peter Lichter, David T. W. Jones, Stefan M. Pfister, Andreas von Deimling, Marcel Kool
Lack of H3K27 trimethylation is associated with 1p/19q codeletion in diffuse gliomas
Katharina Filipski, Yannick Braun, Jenny Zinke, Bastian Roller, Peter Baumgarten, Marlies Wagner, Christian Senft, Pia S. Zeiner, Michael W. Ronellenfitsch, Joachim P. Steinbach, Karl H. Plate, Gilles Gasparoni, Michel Mittelbronn, David Capper, Patrick N. Harter
ALK-positive histiocytosis with KIF5B-ALK fusion in the central nervous system
Calixto-Hope G. Lucas, Ahmed Gilani, David A. Solomon, Xiayuan Liang, Ossama M. Maher, Gabriel Chamyan, Bette K. Kleinschmidt-Demasters, Arie Perry