Ausgabe 5/2015
Inhalt (9 Artikel)
Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury
Peiwen Chen, Xianhua Piao, Paolo Bonaldo
Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies
Jens Wagner, Sybille Krauss, Song Shi, Sergey Ryazanov, Julia Steffen, Carolin Miklitz, Andrei Leonov, Alexander Kleinknecht, Bettina Göricke, Jochen H. Weishaupt, Daniel Weckbecker, Anne M. Reiner, Wolfgang Zinth, Johannes Levin, Dan Ehninger, Stefan Remy, Hans A. Kretzschmar, Christian Griesinger, Armin Giese, Martin Fuhrmann
PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia
Helois Radford, Julie A. Moreno, Nicholas Verity, Mark Halliday, Giovanna R. Mallucci
Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43
Adam K. Walker, Krista J. Spiller, Guanghui Ge, Allen Zheng, Yan Xu, Melissa Zhou, Kalyan Tripathy, Linda K. Kwong, John Q. Trojanowski, Virginia M.-Y. Lee
Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS
Yazi D. Ke, Annika van Hummel, Claire H. Stevens, Amadeus Gladbach, Stefania Ippati, Mian Bi, Wei S. Lee, Sarah Krüger, Julia van der Hoven, Alexander Volkerling, Andre Bongers, Glenda Halliday, Nikolas K. Haass, Matthew Kiernan, Fabien Delerue, Lars M. Ittner
Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS
Kai Y. Soo, Mark Halloran, Vinod Sundaramoorthy, Sonam Parakh, Reka P. Toth, Katherine A. Southam, Catriona A. McLean, Peter Lock, Anna King, Manal A. Farg, Julie D. Atkin
Comparing the efficacy and neuroinflammatory potential of three anti-abeta antibodies
James P. Fuller, Jeffrey B. Stavenhagen, Søren Christensen, Fredrik Kartberg, Martin J. Glennie, Jessica L. Teeling
Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-truncated Abeta in sporadic Alzheimer disease cases and mouse models
Yvonne Bouter, Jose Socrates Lopez Noguerola, Petra Tucholla, Gabriela A. N. Crespi, Michael W. Parker, Jens Wiltfang, Luke A. Miles, Thomas A. Bayer
PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk
Svetlana M. Stamatovic, Nikola Sladojevic, Richard F. Keep, Anuska V. Andjelkovic