Ausgabe 1/2021
Inhalt (306 Artikel)
Validation of the adjusted multi-biomarker disease activity score as a prognostic test for radiographic progression in rheumatoid arthritis: a combined analysis of multiple studies
Jeffrey R. Curtis, Michael E. Weinblatt, Nancy A. Shadick, Cecilie H. Brahe, Mikkel Østergaard, Merete Lund Hetland, Saedis Saevarsdottir, Megan Horton, Brent Mabey, Darl D. Flake II, Rotem Ben-Shachar, Eric H. Sasso, T. W. Huizinga
Younger age and female gender are determinants of underestimated cardiovascular risk in rheumatoid arthritis patients: a prospective cohort study
Daphne C. Rohrich, Eline H. M. van de Wetering, Alexander J. Rennings, Elke E. Arts, Inger L. Meek, Alfons A. den Broeder, Jaap Fransen, Calin D. Popa
Baricitinib inhibits structural joint damage progression in patients with rheumatoid arthritis—a comprehensive review
Paul Emery, Patrick Durez, Axel J. Hueber, Inmaculada de la Torre, Esbjörn Larsson, Thorsten Holzkämper, Yoshiya Tanaka
Increased development of radiographic hip osteoarthritis in individuals with high bone mass: a prospective cohort study
April Hartley, Sarah A. Hardcastle, Monika Frysz, Jon Parkinson, Lavinia Paternoster, Eugene McCloskey, Kenneth E. S. Poole, Muhammad K. Javaid, Mo Aye, Katie Moss, Martin Williams, Jon H. Tobias, Celia L. Gregson
Anti-CD40 antibody KPL-404 inhibits T cell-mediated activation of B cells from healthy donors and autoimmune patients
John Marken, Sujatha Muralidharan, Natalia V. Giltiay
Computer vision applied to dual-energy computed tomography images for precise calcinosis cutis quantification in patients with systemic sclerosis
Anita C. Chandrasekaran, Zhicheng Fu, Reid Kraniski, F. Perry Wilson, Shannon Teaw, Michelle Cheng, Annie Wang, Shangping Ren, Imran M. Omar, Monique E. Hinchcliff
Independent and interactive effect of sitting time and physical activity on prevalence of hyperuricemia: the Henan Rural Cohort Study
Xiaokang Dong, Yuqian Li, Lulu Zhang, Xiaotian Liu, Runqi Tu, Yikang Wang, Ruiying Li, Linlin Li, Jian Hou, Zhenxing Mao, Wenqian Huo, Chongjian Wang
Clinical outcomes of patients with giant cell arteritis treated with tocilizumab in real-world clinical practice: decreased incidence of new visual manifestations
Sebastian Unizony, Timothy J. McCulley, Robert Spiera, Jinglan Pei, Paris N. Sidiropoulos, Jennie H. Best, Christine Birchwood, Andrey Pavlov, John H. Stone
Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis
David A. Fox, Steven K. Lundy, Michael L. Whitfield, Veronica Berrocal, Phillip Campbell, Stephanie Rasmussen, Ray Ohara, Alexander Stinson, Mikel Gurrea-Rubio, Evan Wiewiora, Catherine Spino, Erica Bush, Daniel Furst, Shiv Pillai, Dinesh Khanna
Efficacy and safety of upadacitinib over 84 weeks in Japanese patients with rheumatoid arthritis (SELECT-SUNRISE)
Hideto Kameda, Tsutomu Takeuchi, Kunihiro Yamaoka, Motohiro Oribe, Mitsuhiro Kawano, Masayuki Yokoyama, Aileen L. Pangan, Yuko Konishi, Sebastian Meerwein, Yoshiya Tanaka
The presence of erosive joints is a strong predictor of radiological progression in hand osteoarthritis: results of a 2-year prospective follow-up of the Liège Hand Osteoarthritis Cohort (LIHOC)
Audrey Neuprez, Jean-François Kaux, Médéa Locquet, Charlotte Beaudart, Jean-Yves Reginster
Switching first-line targeted therapy after not reaching low disease activity within 6 months is superior to conservative approach: a propensity score-matched analysis from the ATTRA registry
Lucie Nekvindová, Jiří Vencovský, Karel Pavelka, Pavel Horák, Zlatuše Křístková, Jakub Závada
Connective tissue remodelling is differently modulated by tocilizumab versus methotrexate monotherapy in patients with early rheumatoid arthritis: the AMBITION study
Patryk J. Drobinski, Anne C. Bay-Jensen, Morten A. Karsdal, Samra Sardar, Anne S. Siebuhr
Expansion of circulating peripheral TIGIT+CD226+ CD4 T cells with enhanced effector functions in dermatomyositis
Wenli Li, Chuiwen Deng, Hanbo Yang, Xin Lu, Shanshan Li, Xia Liu, Fang Chen, Lida Chen, Xiaoming Shu, Lu Zhang, Qingyan Liu, Guochun Wang, Qinglin Peng
Symptomatic aortitis at giant cell arteritis diagnosis: a prognostic factor of aortic event
Olivier Espitia, Gauthier Blonz, Geoffrey Urbanski, Cédric Landron, Jérôme Connault, Christian Lavigne, Pascal Roblot, François Maillot, Alexandra Audemard-Verger, Mathieu Artifoni, Cécile Durant, Béatrice Guyomarch, Mohamed Hamidou, Julie Magnant, Christian Agard
Cytomegalovirus infection: friend or foe in rheumatoid arthritis?
Jean-Luc Davignon, Bernard Combe, Alain Cantagrel
Risk of opportunistic infections in patients with rheumatoid arthritis initiating abatacept: cumulative clinical trial data
Teresa A. Simon, Lixian Dong, Kevin L. Winthrop
Impact of baseline clinical and radiological features on outcome of chronic rhinosinusitis in granulomatosis with polyangiitis
Sigrun Skaar Holme, Karin Kilian, Heidi B. Eggesbø, Jon Magnus Moen, Øyvind Molberg
Association study between immune-related miRNAs and mixed connective tissue disease
Barbara Stypińska, Aleksandra Lewandowska, Anna Felis-Giemza, Marzena Olesińska, Agnieszka Paradowska-Gorycka
Chinese SLE Treatment and Research Group Registry (CSTAR) XIII: prevalence and risk factors for chronic scarring alopecia in patients with systemic lupus erythematosus
Yirong Xiang, Mengtao Li, Hui Luo, Yanhong Wang, Xinwang Duan, Cheng Zhao, Feng Zhan, Zhenbiao Wu, Hongbin Li, Min Yang, Jian Xu, Wei Wei, Lijun Wu, Hanxiao You, Junyan Qian, Xiaoxi Yang, Can Huang, Jiuliang Zhao, Qian Wang, Xiaomei Leng, Xinping Tian, Yan Zhao, Xiaofeng Zeng
MicroRNA-320a: an important regulator in the fibrotic process in interstitial lung disease of systemic sclerosis
Yiqun Li, Jing Huang, Chaojun Hu, Jiaxin Zhou, Dong Xu, Yong Hou, Chanyuan Wu, Jiuliang Zhao, Mengtao Li, Xiaofeng Zeng, Changzheng Liu, Qian Wang, Yan Zhao
Photoacoustic and high-frequency ultrasound imaging of systemic sclerosis patients
Khalid Daoudi, Brigit E. Kersten, Cornelia H. M. van den Ende, Frank H. J. van den Hoogen, Madelon C. Vonk, Chris L. de Korte
Circular RNAs in osteoarthritis: indispensable regulators and novel strategies in clinical implications
Wenchao Zhang, Lin Qi, Ruiqi Chen, Jieyu He, Zhongyue Liu, Wanchun Wang, Chao Tu, Zhihong Li
Hsa_circ_0123190 acts as a competitive endogenous RNA to regulate APLNR expression by sponging hsa-miR-483-3p in lupus nephritis
Chunyi Zhang, Congcong Gao, Xueqi Di, Siwan Cui, Wenfang Liang, Wenbo Sun, Menghui Yao, Shengyun Liu, Zhaohui Zheng
Long-term remission and biologic persistence rates: 12-year real-world data
Kieran Murray, Matthew Turk, Yousef Alammari, Francis Young, Phil Gallagher, Tajvur Saber, Ursula Fearon, Douglas J. Veale
The sequence of disease-modifying anti-rheumatic drugs: pathways to and predictors of tocilizumab monotherapy
Daniel H. Solomon, Chang Xu, Jamie Collins, Seoyoung C. Kim, Elena Losina, Vincent Yau, Fredrik D. Johansson
Predictors of radiographic erosion and joint space narrowing progression in patients with early rheumatoid arthritis: a cohort study
Emil Rydell, Kristina Forslind, Jan-Åke Nilsson, Magnus Karlsson, Kristina E. Åkesson, Lennart T. H. Jacobsson, Carl Turesson
Efficacy of plasma exchange for antineutrophil cytoplasmic antibody-associated systemic vasculitis: a systematic review and meta-analysis
Yosuke Yamada, Makoto Harada, Yuuta Hara, Ryohei Iwabuchi, Koji Hashimoto, Shuhei Yamamoto, Yuji Kamijo
The baseline interferon signature predicts disease severity over the subsequent 5 years in systemic lupus erythematosus
Lloyd Mai, Arundip Asaduzzaman, Babak Noamani, Paul R. Fortin, Dafna D. Gladman, Zahi Touma, Murray B. Urowitz, Joan Wither
Is gene expression among women with rheumatoid arthritis dysregulated during a postpartum flare?
Matthew Wright, Mette K. Smed, J. Lee Nelson, Jørn Olsen, Merete L. Hetland, Vibeke Zoffmann, Damini Jawaheer
Serum biomarker panel for the diagnosis of rheumatoid arthritis
Sora Mun, Jiyeong Lee, Mira Park, Jieun Shin, Mi-Kyoung Lim, Hee-Gyoo Kang
Low levels of PCSK9 are associated with remission in patients with rheumatoid arthritis treated with anti-TNF-α: potential underlying mechanisms
Johan Frostegård, Sabbir Ahmed, Ingiäld Hafström, Sofia Ajeganova, Mizanur Rahman
Jo-1 autoantigen-specific B cells are skewed towards distinct functional B cell subsets in anti-synthetase syndrome patients
Jennifer Young-Glazer, Alberto Cisneros III, Erin M. Wilfong, Scott A. Smith, Leslie J. Crofford, Rachel H. Bonami
Pain chronification and the important role of non-disease-specific symptoms in patients with systemic sclerosis
Caroline Evers, Suzana Jordan, Britta Maurer, Mike Oliver Becker, Carina Mihai, Rucsandra Dobrota, Petra Hoederath, Oliver Distler
Association of subchondral bone marrow lesion localization with weight-bearing pain in people with knee osteoarthritis: data from the Osteoarthritis Initiative
Koji Aso, Seyed Mohsen Shahtaheri, Daniel F. McWilliams, David A. Walsh
Correction to: Anti-CD40 antibody KPL-404 inhibits T cell-mediated activation of B cells from healthy donors and autoimmune patients
John Marken, Sujatha Muralidharan, Natalia V. Giltiay
Proinflammatory T cell polarization is already present in patients with early knee osteoarthritis
Nils Rosshirt, Richard Trauth, Hadrian Platzer, Elena Tripel, Timo A. Nees, Hanns-Martin Lorenz, Theresa Tretter, Babak Moradi
Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis
Cuiyan Wu, Sijian Tan, Li Liu, Shiqiang Cheng, Peilin Li, Wenyu Li, Huan Liu, Feng’e Zhang, Sen Wang, Yujie Ning, Yan Wen, Feng Zhang
A bioavailable form of curcumin, in combination with vitamin-D- and omega-3-enriched diet, modifies disease onset and outcomes in a murine model of collagen-induced arthritis
Mahadevappa Hemshekhar, Vidyanand Anaparti, Hani El-Gabalawy, Neeloffer Mookherjee
Concentration of survivin in children with oligo- and polyarticular juvenile idiopathic arthritis (JIA): diagnostic and prognostic value—a single-center study
Joanna Lipinska, Marcin Kaszkowiak, Beata Malachowska, Joanna Swidrowska-Jaros, Elzbieta Smolewska
Ixekizumab, with or without concomitant methotrexate, improves signs and symptoms of PsA: week 52 results from Spirit-P1 and Spirit-P2 studies
Bernard Combe, Tsen-Fang Tsai, J. Eugene Huffstutter, Aubrey Trevelin Sprabery, Chen-Yen Lin, So Young Park, Andris Kronbergs, Matthew M. Hufford, Peter Nash
The gut microbiota in osteoarthritis: where do we stand and what can we do?
Xiaoxia Hao, Xingru Shang, Jiawei Liu, Ruimin Chi, Jiaming Zhang, Tao Xu
Structural changes in the sacroiliac joint on MRI and relationship to ASDAS inactive disease in axial spondyloarthritis: a 2-year study comparing treatment with etanercept in EMBARK to a contemporary control cohort in DESIR
Walter P. Maksymowych, Pascal Claudepierre, Manouk de Hooge, Robert G. Lambert, Robert Landewé, Anna Molto, Désirée van der Heijde, Jack F. Bukowski, Heather Jones, Ron Pedersen, Annette Szumski, Bonnie Vlahos, Maxime Dougados
Treatment persistence of biologics among patients with psoriatic arthritis
Amir Haddad, Tal Gazitt, Ilan Feldhamer, Joy Feld, Arnon Dov Cohen, Idit Lavi, Faten Tatour, Irena Bergman, Devy Zisman
Cluster analysis of phenotypes of patients with Behçet’s syndrome: a large cohort study from a referral center in China
Jun Zou, Jian-feng Luo, Yan Shen, Jian-fei Cai, Jian-long Guan
The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study
Lay Kim Tan, Chun Lai Too, Lina Marcela Diaz-Gallo, Sulaiman Wahinuddin, Ing Soo Lau, Hussein Heselynn, Shahril Nor-Shuhaila, Suk Chyn Gun, Mageswaran Eashwary, Mohamed Said Mohd-Shahrir, Mohd Mokhtar Ainon, Rosman Azmillah, Othman Muhaini, Murad Shahnaz, Lars Alfredsson, Lars Klareskog, Leonid Padyukov
Polysaccharide from Angelica sinensis attenuates SNP-induced apoptosis in osteoarthritis chondrocytes by inducing autophagy via the ERK1/2 pathway
Chao Xu, Su Ni, Chao Zhuang, Chenkai Li, Gongyin Zhao, Shijie Jiang, Liangliang Wang, Ruixia Zhu, Andre J. van Wijnen, Yuji Wang
Using a DAS28-CRP-steered treat-to-target strategy does not eliminate subclinical inflammation as assessed by ultrasonography in rheumatoid arthritis patients in longstanding clinical remission
Lene Terslev, Cecilie Heegaard Brahe, Mikkel Østergaard, Viktoria Fana, Mads Ammitzbøll-Danielsen, Torsten Møller, Simon Krabbe, Merete Lund Hetland, Uffe Møller Døhn
Changes in the proportion of clinical clusters contribute to the phenotypic evolution of Behçet’s disease in Japan
Yutaro Soejima, Yohei Kirino, Mitsuhiro Takeno, Michiko Kurosawa, Masaki Takeuchi, Ryusuke Yoshimi, Yumiko Sugiyama, Shigeru Ohno, Yukiko Asami, Akiko Sekiguchi, Toshihisa Igarashi, Shohei Nagaoka, Yoshiaki Ishigatsubo, Hideaki Nakajima, Nobuhisa Mizuki
Silk fibroin hydrogel scaffolds incorporated with chitosan nanoparticles repair articular cartilage defects by regulating TGF-β1 and BMP-2
Yuan Li, Yanping Liu, Qiang Guo
Efficacy and safety of biosimilar CT-P17 versus reference adalimumab in subjects with rheumatoid arthritis: 24-week results from a randomized study
Jonathan Kay, Janusz Jaworski, Rafal Wojciechowski, Piotr Wiland, Anna Dudek, Marek Krogulec, Slawomir Jeka, Agnieszka Zielinska, Jakub Trefler, Katarzyna Bartnicka-Maslowska, Magdalena Krajewska-Wlodarczyk, Piotr A. Klimiuk, Sang Joon Lee, Yun Ju Bae, Go Eun Yang, Jae Kyoung Yoo, Daniel E. Furst, Edward Keystone
Functional analysis of novel A20 variants in patients with atypical inflammatory diseases
Saori Kadowaki, Kunio Hashimoto, Toyoki Nishimura, Kenichi Kashimada, Tomonori Kadowaki, Norio Kawamoto, Kohsuke Imai, Satoshi Okada, Hirokazu Kanegane, Hidenori Ohnishi
Which patient-reported outcomes do rheumatology patients find important to track digitally? A real-world longitudinal study in ArthritisPower
W. Benjamin Nowell, Kelly Gavigan, Carol L. Kannowski, Zhihong Cai, Theresa Hunter, Shilpa Venkatachalam, Julie Birt, Jennifer Workman, Jeffrey R. Curtis
Needle biopsy compared with surgical biopsy: pitfalls of small biopsy in histologial diagnosis of IgG4-related disease
Yanying Liu, Fei Yang, Xiying Chi, Yuxin Zhang, Jiangnan Fu, Wenjie Bian, Danhua Shen, Zhanguo Li
Detection of knee synovitis using non-contrast-enhanced qDESS compared with contrast-enhanced MRI
Bas A. de Vries, Stephan J. Breda, Bragi Sveinsson, Emily J. McWalter, Duncan E. Meuffels, Gabriel P. Krestin, Brian A. Hargreaves, Garry E. Gold, Edwin H. G. Oei
Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?
Peter Kvacskay, Nina Yao, Jürgen-Heinz Schnotz, Roberta Scarpone, Rui de Albuquerque Carvalho, Karel D. Klika, Wolfgang Merkt, Theresa Tretter, Hanns-Martin Lorenz, Lars-Oliver Tykocinski
Risk factors for mortality of diffuse alveolar hemorrhage in systemic lupus erythematosus: a systematic review and meta-analysis
Mengdi Jiang, Ruxuan Chen, Lidan Zhao, Xuan Zhang
Lymphatic muscle cells contribute to dysfunction of the synovial lymphatic system in inflammatory arthritis in mice
Qianqian Liang, Li Zhang, Hao Xu, Jinlong Li, Yan Chen, Edward M. Schwarz, Qi Shi, Yongjun Wang, Lianping Xing
Macrophage migration inhibitory factor may play a protective role in osteoarthritis
Ming Liu, Zikun Xie, Guang Sun, Liujun Chen, Dake Qi, Hongwei Zhang, Jieying Xiong, Andrew Furey, Proton Rahman, Guanghua Lei, Guangju Zhai
Bisphosphonates as disease-modifying drugs in osteoarthritis preclinical studies: a systematic review from 2000 to 2020
Silvia Fernández-Martín, Mónica López-Peña, Fernando Muñoz, María Permuy, Antonio González-Cantalapiedra
Markers of disease severity and positive family history are associated to significant risk perception in rheumatoid arthritis, while compliance with therapy is not: a cross-sectional study in 415 Mexican outpatients
Irazú Contreras-Yáñez, Pilar Lavielle, Patricia Clark, Virginia Pascual-Ramos
HDL cholesterol efflux capacity and lipid profile in patients with systemic sclerosis
Iván Ferraz-Amaro, Esmeralda Delgado-Frías, Vanesa Hernández-Hernández, Hiurma Sánchez-Pérez, Laura de Armas-Rillo, Estefanía Armas-González, José David Machado, Federico Diaz-González
Serum complement 3 is a potential biomarker for assessing disease activity in Takayasu arteritis
Chen Rongyi, Ma Lingying, Lv Peng, Lin Jiang, Li Chaolun, Yan Yan, Jin Xuejuan, Dai Xiaomin, Ji Zongfei, Chen Huiyong, Ma Lili, Sun Ying, Jiang Lindi
Association of systemic lupus erythematosus autoantibody diversity with breast cancer protection
Ami A. Shah, Takeru Igusa, Daniel Goldman, Jessica Li, Livia Casciola-Rosen, Antony Rosen, Michelle Petri
Development of a model for predicting the 4-year risk of symptomatic knee osteoarthritis in China: a longitudinal cohort study
Limin Wang, Han Lu, Hongbo Chen, Shida Jin, Mengqi Wang, Shaomei Shang
Comprehensive assessment of alterations in hand deformities over 11 years in patients with rheumatoid arthritis using cluster analysis and analysis of covariance
Shogo Toyama, Daisaku Tokunaga, Shinji Tsuchida, Rie Kushida, Ryo Oda, Yutaka Kawahito, Kenji Takahashi
Advanced machine learning for predicting individual risk of flares in rheumatoid arthritis patients tapering biologic drugs
Asmir Vodencarevic, Koray Tascilar, Fabian Hartmann, Michaela Reiser, Axel J. Hueber, Judith Haschka, Sara Bayat, Timo Meinderink, Johannes Knitza, Larissa Mendez, Melanie Hagen, Gerhard Krönke, Jürgen Rech, Bernhard Manger, Arnd Kleyer, Marcus Zimmermann-Rittereiser, Georg Schett, David Simon
Elucidating the cellular mechanism for E2-induced dermal fibrosis
DeAnna Baker Frost, Alisa Savchenko, Adeyemi Ogunleye, Milton Armstrong, Carol Feghali-Bostwick
Incident gout and weight change patterns: a retrospective cohort study of US adults
Lu Bai, Jian-Bo Zhou, Tao Zhou, Roger B. Newson, Marly Augusto Cardoso
Safety and efficacy of low-dose intravenous arsenic trioxide in systemic lupus erythematosus: an open-label phase IIa trial (Lupsenic)
Mohamed Hamidou, Antoine Néel, Joel Poupon, Zahir Amoura, Mikael Ebbo, Jean Sibilia, Jean-Francois Viallard, Benjamin Gaborit, Christelle Volteau, Jean Benoit Hardouin, Eric Hachulla, François Rieger
Hip osteoarthritis signs and symptoms are associated with increased fall risk among community-dwelling older adults with chronic low back pain: a prospective study
Patrick J. Knox, Peter C. Coyle, Jenifer M. Pugliese, Ryan T. Pohlig, Jaclyn M. Sions, Gregory E. Hicks
The effects of WeChat-based educational intervention in patients with ankylosing spondylitis: a randomized controlled trial
Yuqing Song, Xia Xie, Yanling Chen, Ying Wang, Hui Yang, Anliu Nie, Hong Chen
Correction to: Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis
David A. Fox, Steven K. Lundy, Michael L. Whitfield, Veronica Berrocal, Phillip Campbell, Stephanie Rasmussen, Ray Ohara, Alexander Stinson, Mikel Gurrea-Rubio, Evan Wiewiora, Catherine Spino, Erica Bush, Daniel Furst, Shiv Pillai, Dinesh Khanna
Visit-to-visit variability of serum uric acid measurements and the risk of all-cause mortality in the general population
Xue Tian, Anxin Wang, Yingting Zuo, Shuohua Chen, Licheng Zhang, Shouling Wu, Yanxia Luo
The comparative effect of exposure to various risk factors on the risk of hyperuricaemia: diet has a weak causal effect
Ruth K. G. Topless, Tanya J. Major, Jose C. Florez, Joel N. Hirschhorn, Murray Cadzow, Nicola Dalbeth, Lisa K. Stamp, Philip L. Wilcox, Richard J. Reynolds, Joanne B. Cole, Tony R. Merriman
18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study
Emmanuel Ledoult, Maxime Morelle, Michael Soussan, Arsène Mékinian, Hélène Béhal, Vincent Sobanski, Eric Hachulla, Damien Huglo, Noémie Le Gouellec, Martine Remy-Jardin, Clio Baillet, David Launay
Serum chitinase-3-like 1 protein is a useful biomarker to assess disease activity in ANCA-associated vasculitis: an observational study
Sung Soo Ahn, Taejun Yoon, Yong-Beom Park, Maria Prendecki, Gurjeet Bhangal, Stephen P. McAdoo, Sang-Won Lee
HDAC2 interacts with microRNA-503-5p to regulate SGK1 in osteoarthritis
Zheng Wang, Nan Zhou, Wengang Wang, Yangke Yu, Lei Xia, Ning Li
Association of glucocorticoid doses and emotional health in lupus low disease activity state (LLDAS): a cross-sectional study
Yoshia Miyawaki, Sayaka Shimizu, Yusuke Ogawa, Ken-ei Sada, Yu Katayama, Yosuke Asano, Keigo Hayashi, Yuriko Yamamura, Sumie Hiramatsu-Asano, Keiji Ohashi, Michiko Morishita, Haruki Watanabe, Mariko Takano-Narazaki, Yoshinori Matsumoto, Nobuyuki Yajima, Ryusuke Yoshimi, Yasuhiro Shimojima, Shigeru Ohno, Hiroshi Kajiyama, Kunihiro Ichinose, Shuzo Sato, Michio Fujiwara, Hajime Yamazaki, Yosuke Yamamoto, Jun Wada, Shunichi Fukuhara
Transcriptome-wide study of TNF-inhibitor therapy in rheumatoid arthritis reveals early signature of successful treatment
James Oliver, Nisha Nair, Gisela Orozco, Samantha Smith, Kimme L. Hyrich, Ann Morgan, John Isaacs, Anthony G. Wilson, Anne Barton, Darren Plant
Integrating transcriptome-wide association study and mRNA expression profile identified candidate genes related to hand osteoarthritis
Jiawen Xu, Yi Zeng, Haibo Si, Yuan Liu, Mingyang Li, Junfeng Zeng, Bin Shen
A meta-analysis of the epidemiology of giant cell arteritis across time and space
Katherine J. Li, Daniel Semenov, Matthew Turk, Janet Pope
Evaluation of whole-body modalities for diagnosis of multifocal osteonecrosis—a pilot study
Shunichi Yokota, Keita Sakamoto, Yukie Shimizu, Tsuyoshi Asano, Daisuke Takahashi, Kohsuke Kudo, Norimasa Iwasaki, Tomohiro Shimizu
Positive feedback regulation between USP15 and ERK2 inhibits osteoarthritis progression through TGF-β/SMAD2 signaling
Wenjuan Wang, Yanhui Zhu, Zhenyu Sun, Chen Jin, Xiang Wang
A randomized, placebo-controlled experimental medicine study of RIPK1 inhibitor GSK2982772 in patients with moderate to severe rheumatoid arthritis
Kathleen Weisel, Scott Berger, Katie Thorn, Peter C. Taylor, Charles Peterfy, Hilary Siddall, Debra Tompson, Susanne Wang, Emilia Quattrocchi, Susan W. Burriss, Jochen Walter, Paul Peter Tak
Effectiveness and safety of mepolizumab in combination with corticosteroids in patients with eosinophilic granulomatosis with polyangiitis
Masanobu Ueno, Ippei Miyagawa, Kazuhisa Nakano, Shigeru Iwata, Kentaro Hanami, Shunsuke Fukuyo, Satoshi Kubo, Yusuke Miyazaki, Akio Kawabe, Hiroko Yoshinari, Shingo Nakayamada, Yoshiya Tanaka
Correction to: Validity and diagnostic performance of fluorescence optical imaging measuring synovitis in hand osteoarthritis: baseline results from the Nor-Hand cohort
Øystein Maugesten, Alexander Mathiessen, Hilde Berner Hammer, Sigrid Valen Hestetun, Tore Kristian Kvien, Till Uhlig, Sarah Ohrndorf, Ida Kristin Haugen
Neutrophil extracellular trap clearance by synovial macrophages in gout
Ji Hye Jeong, Su Jin Choi, Soo Min Ahn, Ji Seon Oh, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong
The troubling liaison between cancer and metabolic syndrome in chronic inflammatory rheumatic diseases
Giovanni Cioffi, Ombretta Viapiana, Luigi Tarantini, Giovanni Orsolini, Luca Idolazzi, Federica Ognibeni, Andrea Dalbeni, Davide Gatti, Angelo Fassio, Giovanni Adami, Maurizio Rossini, Alessandro Giollo
Serious infections in ANCA-associated vasculitides in the biologic era: real-life data from a multicenter cohort of 162 patients
Konstantinos Thomas, Evangelia Argyriou, Noemin Kapsala, Alexandros Panagiotopoulos, Aglaia Chalkia, Emilia Hadziyannis, Kyriaki Boki, Pelagia Katsimbri, Dimitrios T. Boumpas, Panagiota Giannou, Dimitrios Petras, Dimitrios Vassilopoulos
Usefulness of tissue inhibitor of metalloproteinase 1 as a predictor of sustained remission in patients with antineutrophil cytoplasmic antibody-associated vasculitis
Jun Ishizaki, Ayako Takemori, Kenta Horie, Daisuke Hiraoka, Koichiro Suemori, Takuya Matsumoto, Ken-ei Sada, Koichi Amano, Masayoshi Harigai, Yoshihiro Arimura, Hirofumi Makino, Katsuto Takenaka, Nobuaki Takemori, Hitoshi Hasegawa, Yohko Murakawa, Eri Muso, Atsushi Komatsuda, Satoshi Ito, Takao Fujii, Atsushi Kawakami, Izaya Nakaya, Takao Saito, Takafumi Ito, Nobuhito Hirawa, Masahiro Yamamura, Masaaki Nakano, Kosaku Nitta, Makoto Ogura, Taio Naniwa, Shoichi Ozaki, Junichi Hirahashi, Noriyoshi Ogawa, Tatsuo Hosoya, Takashi Wada, Satoshi Horikoshi, Yasushi Kawaguchi, Taichi Hayashi, Masaharu Yoshida, Tsuyoshi Watanabe, Daijo Inaguma, Kazuhiko Tsuruya, Noriyuki Homma, Tsutomu Takeuchi, Naoki Nakagawa, Shinichi Takeda, Ritsuko Katabuchi, Masayuki Iwano, Tatsuya Atsumi, Shoichi Fujimoto, Shogo Banno, Takahiko Sugihara, Masaki Kobayashi, Kunihiro Yamagata, Sakae Homma, Hiroaki Dobashi, Naotake Tsuboi, Akihiro Ishizu, Hitoshi Sugiyama
Vision loss in patients with giant cell arteritis treated with tocilizumab
Jennifer Amsler, Iveta Kysela, Christoph Tappeiner, Luca Seitz, Lisa Christ, Godehard Scholz, Odile Stalder, Florian Kollert, Stephan Reichenbach, Peter M. Villiger
Diet-induced obesity leads to behavioral indicators of pain preceding structural joint damage in wild-type mice
Geoffrey J. Kerr, Bethia To, Ian White, Magali Millecamps, Frank Beier, Matthew W. Grol, Laura S. Stone, Cheryle A. Séguin
Relationships between psoriatic arthritis composite measures of disease activity with patient-reported outcomes in phase 3 studies of tofacitinib
Laura C. Coates, Andrew G. Bushmakin, Oliver FitzGerald, Dafna D. Gladman, Lara Fallon, Joseph C. Cappelleri, Ming-Ann Hsu, Philip S. Helliwell
Impact of disease activity on impaired glucose metabolism in patients with rheumatoid arthritis
Gorica G. Ristić, Vesna Subota, Dejana Stanisavljević, Danilo Vojvodić, Arsen D. Ristić, Branislava Glišić, Milan Petronijević, Dušan Z. Stefanović
Urinary sodium-to-potassium ratio associates with hypertension and current disease activity in patients with rheumatoid arthritis: a cross-sectional study
Hiroto Minamino, Masao Katsushima, Motomu Hashimoto, Yoshihito Fujita, Tamami Yoshida, Kaori Ikeda, Nozomi Isomura, Yasuo Oguri, Wataru Yamamoto, Ryu Watanabe, Kosaku Murakami, Koichi Murata, Kohei Nishitani, Masao Tanaka, Hiromu Ito, Koichiro Ohmura, Shuichi Matsuda, Nobuya Inagaki, Akio Morinobu
Total metabolic lesion volume of lymph nodes measured by 18F-FDG PET/CT: a new predictor of macrophage activation syndrome in adult-onset Still’s disease
Liyan Wan, Yuting Gao, Jieyu Gu, Huihui Chi, Zhihong Wang, Qiongyi Hu, Jinchao Jia, Tingting Liu, Biao Li, Jialin Teng, Honglei Liu, Xiaobing Cheng, Junna Ye, Yutong Su, Chengde Yang, Hui Shi, Min Zhang
Clinical features and relapse risks of IgG4-related ophthalmic disease: a single-center experience in China
Zhen Zhao, Dapeng Mou, Ziqiao Wang, Qiaozhu Zeng, Zhenfan Wang, Jimeng Xue, Limin Ren, Yanying Liu, Yin Su
Stimulation of regulatory T cells with Lactococcus lactis expressing enterotoxigenic E. coli colonization factor antigen 1 retains salivary flow in a genetic model of Sjögren’s syndrome
Ali Akgul, Massimo Maddaloni, Sang Mu Jun, Andrew S. Nelson, Vanessa Aguilera Odreman, Carol Hoffman, Ella Bhagyaraj, Alexandria Voigt, Jeffrey R. Abbott, Cuong Q. Nguyen, David W. Pascual
Effect of combined pulmonary fibrosis and emphysema on patients with connective tissue diseases and systemic sclerosis: a systematic review and meta-analysis
Bon San Koo, Kyu Yong Park, Hyun Jung Lee, Hyun Jung Kim, Hyeong Sik Ahn, Shin-Young Yim, Jae-Bum Jun
Correction to: Single-cell transcriptome conservation in a comparative analysis of fresh and cryopreserved human skin tissue: pilot in localized scleroderma
Emily Mirizio, Tracy Tabib, Xinjun Wang, Wei Chen, Christopher Liu, Robert Lafyatis, Heidi Jacobe, Kathryn S. Torok
Clinical characteristics and outcome of IgG4-related disease with hypocomplementemia: a prospective cohort study
Linyi Peng, Hui Lu, Jiaxin Zhou, Panpan Zhang, Jieqiong Li, Zheng Liu, Di Wu, Shangzhu Zhang, Yunjiao Yang, Wei Bai, Li Wang, Yunyun Fei, Wen Zhang, Yan Zhao, Xiaofeng Zeng, Fengchun Zhang
The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice
Shingo Ishihara, Alia M. Obeidat, David L. Wokosin, Dongjun Ren, Richard J. Miller, Anne-Marie Malfait, Rachel E. Miller
Periostin loss-of-function protects mice from post-traumatic and age-related osteoarthritis
Mukundan Attur, Xin Duan, Lei Cai, Tianzhen Han, Weili Zhang, Eric D. Tycksen, Jonathan Samuels, Robert H. Brophy, Steven B. Abramson, Muhammad Farooq Rai
Change in dietary inflammatory index score is associated with control of long-term rheumatoid arthritis disease activity in a Japanese cohort: the TOMORROW study
Yoshinari Matsumoto, Nitin Shivappa, Yuko Sugioka, Masahiro Tada, Tadashi Okano, Kenji Mamoto, Kentaro Inui, Daiki Habu, James R. Hebert, Tatsuya Koike
Deep learning for detection of radiographic sacroiliitis: achieving expert-level performance
Keno K. Bressem, Janis L. Vahldiek, Lisa Adams, Stefan Markus Niehues, Hildrun Haibel, Valeria Rios Rodriguez, Murat Torgutalp, Mikhail Protopopov, Fabian Proft, Judith Rademacher, Joachim Sieper, Martin Rudwaleit, Bernd Hamm, Marcus R. Makowski, Kay-Geert Hermann, Denis Poddubnyy
Efficacy and safety of sprifermin injection for knee osteoarthritis treatment: a meta-analysis
Ni Zeng, Xin-Yuan Chen, Zhi-Peng Yan, Jie-Ting Li, Tao Liao, Guo-Xin Ni
Age at menarche, age at natural menopause, and risk of rheumatoid arthritis — a Mendelian randomization study
Jingjing Zhu, Zheng Niu, Lars Alfredsson, Lars Klareskog, Leonid Padyukov, Xia Jiang
Synovial fluid neutrophils in oligoarticular juvenile idiopathic arthritis have an altered phenotype and impaired effector functions
Sabine Arve-Butler, Tobias Schmidt, Anki Mossberg, Elisabet Berthold, Birgitta Gullstrand, Anders A. Bengtsson, Fredrik Kahn, Robin Kahn
Phenotypic alteration of macrophages during osteoarthritis: a systematic review
Xiaobo Zhu, Chien-Wei Lee, Hongtao Xu, Yu-Fan Wang, Patrick S. H. Yung, Yangzi Jiang, Oscar K. Lee
Vaspin in atherosclerotic disease and cardiovascular risk in axial spondyloarthritis: a genetic and serological study
Javier Rueda-Gotor, Raquel López-Mejías, Sara Remuzgo-Martínez, Verónica Pulito-Cueto, Alfonso Corrales, Leticia Lera-Gómez, Virginia Portilla, Íñigo González-Mazón, Ricardo Blanco, Rosa Expósito, Cristina Mata, Javier Llorca, Vanesa Hernández-Hernández, Carlos Rodríguez-Lozano, Nuria Barbarroja, Rafaela Ortega Castro, Esther Vicente, Cristina Fernández-Carballido, María Paz Martínez-Vidal, David Castro-Corredor, Joaquín Anino-Fernández, Diana Peiteado, Chamaida Plasencia-Rodríguez, Eva Galíndez-Agirregoikoa, María Luz García-Vivar, Oreste Gualillo, Juan Carlos Quevedo-Abeledo, Santos Castañeda, Iván Ferraz-Amaro, Miguel Á. González-Gay, Fernanda Genre
Accuracy, patient-perceived usability, and acceptance of two symptom checkers (Ada and Rheport) in rheumatology: interim results from a randomized controlled crossover trial
Johannes Knitza, Jacob Mohn, Christina Bergmann, Eleni Kampylafka, Melanie Hagen, Daniela Bohr, Harriet Morf, Elizabeth Araujo, Matthias Englbrecht, David Simon, Arnd Kleyer, Timo Meinderink, Wolfgang Vorbrüggen, Cay Benedikt von der Decken, Stefan Kleinert, Andreas Ramming, Jörg H. W. Distler, Nicolas Vuillerme, Achim Fricker, Peter Bartz-Bazzanella, Georg Schett, Axel J. Hueber, Martin Welcker
Early detection of osteoarthritis in the rat with an antibody specific to type II collagen modified by reactive oxygen species
Anne Gigout, Donata Harazin, Louise M. Topping, Didier Merciris, Sven Lindemann, Christian Brenneis, Ahuva Nissim
Upregulated endonuclease Regnase-1 suppresses osteoarthritis by forming a negative feedback loop of catabolic signaling in chondrocytes
Jeong-In Yang, Jang-Soo Chun
Risk of gout among Taiwanese adults with ALDH-2 rs671 polymorphism according to BMI and alcohol intake
Yu-Ruey Liu, Disline Manli Tantoh, Chuan-Chao Lin, Chih-Hsuan Hsiao, Yung-Po Liaw
Comparison of the drug retention and reasons for discontinuation of tumor necrosis factor inhibitors and interleukin-6 inhibitors in Japanese patients with elderly-onset rheumatoid arthritis—the ANSWER cohort study
Sadao Jinno, Akira Onishi, Maureen Dubreuil, Motomu Hashimoto, Wataru Yamamoto, Koichi Murata, Tohru Takeuchi, Takuya Kotani, Yuichi Maeda, Kosuke Ebina, Yonsu Son, Hideki Amuro, Ryota Hara, Masaki Katayama, Jun Saegusa
Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin
Matthew Mannarino, Hosni Cherif, Li Li, Kai Sheng, Oded Rabau, Peter Jarzem, Michael H. Weber, Jean A. Ouellet, Lisbet Haglund
Re-treatment with etanercept is as effective as the initial firstline treatment in patients with juvenile idiopathic arthritis
Jens Klotsche, Ariane Klein, Martina Niewerth, Paula Hoff, Daniel Windschall, Ivan Foeldvari, Johannes-Peter Haas, Gerd Horneff, Kirsten Minden
Comparative efficacy of subcutaneous (CT-P13) and intravenous infliximab in adult patients with rheumatoid arthritis: a network meta-regression of individual patient data from two randomised trials
Bernard Combe, Yannick Allanore, Rieke Alten, Roberto Caporali, Patrick Durez, Florenzo Iannone, Michael T. Nurmohamed, Mondher Toumi, Sang Joon Lee, Taek Sang Kwon, Jiwon Noh, Gahee Park, Dae Hyun Yoo
Mitochondrial protein CMPK2 regulates IFN alpha-enhanced foam cell formation, potentially contributing to premature atherosclerosis in SLE
Jenn-Haung Lai, Li-Feng Hung, Chuan-Yueh Huang, De-Wei Wu, Chien-Hsiang Wu, Ling-Jun Ho
Mobile App-based documentation of patient-reported outcomes — 3-months results from a proof-of-concept study on modern rheumatology patient management
Jutta G. Richter, Christina Nannen, Gamal Chehab, Hasan Acar, Arnd Becker, Reinhart Willers, Dörte Huscher, Matthias Schneider
Esophagus involvement in systemic sclerosis: ultrasound parameters and association with clinical manifestations
Li Ma, Qingli Zhu, Yan Zhang, Jianchu Li, Yuxin Jiang, Dong Xu, Xiaofeng Zeng, Yong Hou, He Liu
“Walking into the unknown…” key challenges of pregnancy and early parenting with inflammatory arthritis: a systematic review and thematic synthesis of qualitative studies
Nevena Rebić, Ria Garg, Ursula Ellis, Vanessa Kitchin, Sarah Munro, Glen Hazlewood, Neda Amiri, Nick Bansback, Mary A. De Vera
Regulation of osteoclastogenesis by mast cell in rheumatoid arthritis
Kyoung-Woon Kim, Bo-Mi Kim, Ji-Yeon Won, Hong-Ki Min, Kyung-Ann Lee, Sang-Heon Lee, Hae-Rim Kim
Performance of the UCLA Scleroderma Clinical Trials Consortium Gastrointestinal Tract 2.0 instrument as a clinical decision aid in the routine clinical care of patients with systemic sclerosis
Norina Zampatti, Alexandru Garaiman, Suzana Jordan, Rucsandra Dobrota, Mike Oliver Becker, Britta Maurer, Oliver Distler, Carina Mihai
Application of systems biology-based in silico tools to optimize treatment strategy identification in Still’s disease
Cristina Segú-Vergés, Mireia Coma, Christoph Kessel, Serge Smeets, Dirk Foell, Anna Aldea
Bone mineral density and microarchitecture among Chinese patients with rheumatoid arthritis: a cross-sectional study with HRpQCT
Shangyi Jin, Mengtao Li, Qian Wang, Xiaofeng Zeng, Weibo Xia, Wei Yu, Wenmin Guan, Evelyn Hsieh
Cold-inducible RNA-binding protein (CIRP) potentiates uric acid-induced IL-1β production
Yuya Fujita, Toru Yago, Haruki Matsumoto, Tomoyuki Asano, Naoki Matsuoka, Jumpei Temmoku, Shuzo Sato, Makiko Yashiro-Furuya, Eiji Suzuki, Hiroshi Watanabe, Atsushi Kawakami, Kiyoshi Migita
Strategies for increasing gait speed in patients with hip osteoarthritis: their clinical significance and effects on hip loading
Hiroshige Tateuchi, Haruhiko Akiyama, Koji Goto, Kazutaka So, Yutaka Kuroda, Noriaki Ichihashi
Efficacy and safety of gout flare prophylaxis and therapy use in people with chronic kidney disease: a Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN)-initiated literature review
Huai Leng Pisaniello, Mark C. Fisher, Hamish Farquhar, Ana Beatriz Vargas-Santos, Catherine L. Hill, Lisa K. Stamp, Angelo L. Gaffo
Pro-inflammatory effects of human apatite crystals extracted from patients suffering from calcific tendinopathy
Julien Herman, Benoit Le Goff, Julien De Lima, Régis Brion, Catherine Chevalier, Frédéric Blanchard, Christelle Darrieutort-Laffite
Proteome study of cutaneous lupus erythematosus (CLE) and dermatomyositis skin lesions reveals IL-16 is differentially upregulated in CLE
Timothy B. Niewold, Alexander Meves, Julia S. Lehman, Karin Popovic-Silwerfeldt, Aliisa Häyry, Therese Söderlund-Matell, Cristine M. Charlesworth, Benjamin Madden, Ingrid E. Lundberg, Marie Wahren-Herlenius, Elisabet Svenungsson, Vilija Oke
Soluble guanylate cyclase stimulator reduced the gastrointestinal fibrosis in bleomycin-induced mouse model of systemic sclerosis
Yuzuru Yamamoto, Takaichi Okano, Hirotaka Yamada, Kengo Akashi, Sho Sendo, Yo Ueda, Akio Morinobu, Jun Saegusa
Evaluation of the severe preeclampsia classification criterion for antiphospholipid syndrome in a study of 40 patients
Maddalena Larosa, Véronique Le Guern, Nathalie Morel, Mériem Belhocine, Amelia Ruffatti, Nicolas Martin Silva, Romain Paule, Luc Mouthon, Michel Dreyfus, Jean-Charles Piette, Odile Souchaud-Debouverie, Catherine Deneux-Tharaux, Gaelle Guettrot-Imbert, Vassilis Tsatsaris, Emmanuelle Pannier-Metzger, Anne Murarasu, Andrea Doria, Nathalie Costedoat-Chalumeau
Decreased microRNA-155 in Behcet’s disease leads to defective control of autophagy thereby stimulating excessive proinflammatory cytokine production
Liang Liang, Qingyun Zhou, Lujia Feng
Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses
Kotaro Matsumoto, Takahiko Kurasawa, Keiko Yoshimoto, Katsuya Suzuki, Tsutomu Takeuchi
Fli1 deficiency suppresses RALDH1 activity of dermal dendritic cells and related induction of regulatory T cells: a possible role in scleroderma
Shunsuke Miura, Yusuke Watanabe, Ryosuke Saigusa, Takashi Yamashita, Kouki Nakamura, Megumi Hirabayashi, Takuya Miyagawa, Ayumi Yoshizaki, Maria Trojanowska, Shinichi Sato, Yoshihide Asano
Clinical characteristics and prognosis of patients with isolated thrombotic vs. obstetric antiphospholipid syndrome: a prospective cohort study
Hui Jiang, Chu-Han Wang, Nan Jiang, Jing Li, Chan-Yuan Wu, Qian Wang, Meng-Tao Li, Xin-Ping Tian, Jiu-Liang Zhao, Yan Zhao, Xiao-Feng Zeng
Correction to: Transcriptome-wide study of TNF-inhibitor therapy in rheumatoid arthritis reveals early signature of successful treatment
James Oliver, Nisha Nair, Gisela Orozco, Samantha Smith, Kimme L. Hyrich, Ann Morgan, John Isaacs, Anthony G. Wilson, Anne Barton, Darren Plant
Pre-pregnancy serum complement C3 level is a predictor of preterm birth for pregnancies with systemic lupus erythematosus
Yuri Hiramatsu, Kentaro Isoda, Takuya Kotani, Eri Nakamura, Yumiko Wada, Youhei Fujiki, Shigeki Makino, Daisuke Fujita, Tohru Takeuchi
Serial Lipocalin 2 and Oncostatin M levels reflect inflammation status and treatment response in axial spondyloarthritis
Florence W. L. Tsui, Aifeng Lin, Ismail Sari, Zhenbo Zhang, Hing Wo Tsui, Robert D. Inman
Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways
Jiansen Lu, Hongbo Zhang, Jianying Pan, Zhiqiang Hu, Liangliang Liu, Yanli Liu, Xiao Yu, Xiaochun Bai, Daozhang Cai, Haiyan Zhang
Assessment of the efficacy and safety of tocilizumab in patients over 80 years old with giant cell arteritis
Hubert de Boysson, Maelle Le Besnerais, Félix Blaison, Aurélie Daumas, Pierre-André Jarrot, François Perrin, Nathalie Tieulié, Alexandre Maria, Pierre Duffau, Bruno Gombert, Maxime Samson, Olivier Espitia, Marc Lambert, Arsène Mékinian, Achille Aouba
Tofacitinib downregulates antiviral immune defence in keratinocytes and reduces T cell activation
Heike C. Hawerkamp, Alina Domdey, Lisa Radau, Philipp Sewerin, Péter Oláh, Bernhard Homey, Stephan Meller
Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs
Dong Wang, Robert Hartman, Chao Han, Chao-ming Zhou, Brandon Couch, Matias Malkamaki, Vera Roginskaya, Bennett Van Houten, Steven J. Mullett, Stacy G. Wendell, Michael J. Jurczak, James Kang, Joon Lee, Gwendolyn Sowa, Nam Vo
Opioid users show worse baseline knee osteoarthritis and faster progression of degenerative changes: a retrospective case-control study based on data from the Osteoarthritis Initiative (OAI)
Jannis Bodden, Gabby B. Joseph, Silvia Schirò, John A. Lynch, Nancy E. Lane, Charles E. McCulloch, Michael C. Nevitt, Thomas M. Link
Circulating mature granzyme B+ T cells distinguish Crohn’s disease-associated axial spondyloarthritis from axial spondyloarthritis and Crohn’s disease
Adam R. Lefferts, Emilie H. Regner, Andrew Stahly, Becky O’Rourke, Mark E. Gerich, Blair P. Fennimore, Frank I. Scott, Alison E. Freeman, Ken Jones, Kristine A. Kuhn
Serum checkpoint molecules in patients with IgG4-related disease (IgG4-RD)
Haruki Matsumoto, Yuya Fujita, Naoki Matsuoka, Jumpei Temmoku, Makiko Yashiro-Furuya, Tomoyuki Asano, Shuzo Sato, Hiroshi Watanabe, Eiji Suzuki, Sosuke Tsuji, Shoichi Fukui, Masataka Umeda, Naoki Iwamoto, Atsushi Kawakami, Kiyoshi Migita
Correction to: The effects of WeChat-based educational intervention in patients with ankylosing spondylitis: a randomized controlled trial
Yuqing Song, Xia Xie, Yanling Chen, Ying Wang, Hui Yang, Anliu Nie, Hong Chen
Expanding diagnostic approach in patients with osteonecrosis
José A. Gómez-Puerta, Pilar Peris
The PICASO cloud platform for improved holistic care in rheumatoid arthritis treatment—experiences of patients and clinicians
Jutta G. Richter, Gamal Chehab, Catarina Schwartz, Elisabeth Ricken, Monika Tomczak, Hasan Acar, Henrike Gappa, Carlos A. Velasco, Peter Rosengren, Armanas Povilionis, Matthias Schneider, Jesper Thestrup
Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats
Qi Sun, Fa-Ming Tian, Fang Liu, Jia-Kang Fang, Yun-Peng Hu, Qiang-Qiang Lian, Zhuang Zhou, Liu Zhang
IgG and IgA autoantibodies against L1 ORF1p expressed in granulocytes correlate with granulocyte consumption and disease activity in pediatric systemic lupus erythematosus
Kennedy C. Ukadike, Kathryn Ni, Xiaoxing Wang, Martin S. Taylor, John LaCava, Lauren M. Pachman, Mary Eckert, Anne Stevens, Christian Lood, Tomas Mustelin
Serum TNFα levels at 24 h after certolizumab pegol predict effectiveness at week 12 in patients with rheumatoid arthritis from TSUBAME study
Yusuke Miyazaki, Kazuhisa Nakano, Shingo Nakayamada, Satoshi Kubo, Shigeru Iwata, Kentaro Hanami, Shunsuke Fukuyo, Ippei Miyagawa, Ayako Yamaguchi, Akio Kawabe, Kazuyoshi Saito, Yoshiya Tanaka
An update on targeted therapies in systemic sclerosis based on a systematic review from the last 3 years
Corrado Campochiaro, Yannick Allanore
Prevalence of ultrasound-detected knee synovial abnormalities in a middle-aged and older general population—the Xiangya Osteoarthritis Study
Ting Jiang, Tuo Yang, Weiya Zhang, Michael Doherty, Yuqing Zhang, Jie Wei, Aliya Sarmanova, Michelle Hall, Zidan Yang, Jiatian Li, Gwen S. Fernandes, Abasiama D. Obotiba, Sameer A. Gohir, Philip Courtney, Chao Zeng, Guanghua Lei
The heterogeneous human memory CCR6+ T helper-17 populations differ in T-bet and cytokine expression but all activate synovial fibroblasts in an IFNγ-independent manner
Wendy Dankers, Hannah den Braanker, Sandra M. J. Paulissen, Jan Piet van Hamburg, Nadine Davelaar, Edgar M. Colin, Erik Lubberts
Tumour necrosis factor inhibitors reduce aortic stiffness progression in patients with long-standing rheumatoid arthritis
Alessandro Giollo, Giovanni Cioffi, Federica Ognibeni, Giovanni Orsolini, Andrea Dalbeni, Riccardo Bixio, Giovanni Adami, Angelo Fassio, Luca Idolazzi, Davide Gatti, Maurizio Rossini, Ombretta Viapiana
Exosomal circ-BRWD1 contributes to osteoarthritis development through the modulation of miR-1277/TRAF6 axis
Zhenye Guo, Huan Wang, Feng Zhao, Min Liu, Feida Wang, Mingming Kang, Weifu He, Zhi Lv
Clinical risk factors associated with radiographic osteoarthritis progression among people with knee pain: a longitudinal study
Milena Simic, Alison R. Harmer, Maria Agaliotis, Lillias Nairn, Lisa Bridgett, Lyn March, Milana Votrubec, John Edmonds, Mark Woodward, Richard Day, Marlene Fransen
Is Behçet’s syndrome associated with an increased risk of ischemic heart disease? A real-world evidence in Taiwan
Chun-Yu Lin, Hung-An Chen, Chun-Hsin Wu, Yu-Jih Su, Tsai-Ching Hsu, Chung-Yuan Hsu
Disease activity influences the reclassification of rheumatoid arthritis into very high cardiovascular risk
Iván Ferraz-Amaro, Alfonso Corrales, Juan Carlos Quevedo-Abeledo, Nuria Vegas-Revenga, Ricardo Blanco, Virginia Portilla, Belén Atienza-Mateo, Miguel Á. González-Gay
Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis
M. Kristen Demoruelle, Hong Wang, Ryan L. Davis, Ashley Visser, Johnny Hoang, Jill M. Norris, V. Michael Holers, Kevin D. Deane, Erika Darrah
Plasma metabolomic profiling in patients with rheumatoid arthritis identifies biochemical features predictive of quantitative disease activity
Benjamin Hur, Vinod K. Gupta, Harvey Huang, Kerry A. Wright, Kenneth J. Warrington, Veena Taneja, John M. Davis III, Jaeyun Sung
Site-specific resolution of enthesitis in patients with axial spondyloarthritis treated with tumor necrosis factor inhibitors
Michael J. Nissen, Burkhard Möller, Adrian Ciurea, Ruediger B. Mueller, Patrick Zueger, Martin Schulz, Fabiana Ganz, Almut Scherer, Eleftherios Papagiannoulis, Thomas Hügle
Does methotrexate influence COVID-19 infection? Case series and mechanistic data
Fabian Schälter, Kerstin Dürholz, Laura Bucci, Gerd Burmester, Roberto Caporali, Camille Figuereido, Jaime Fogagnolo Cobra, Bernhard Manger, Mario M. Zaiss, Georg Schett
Therapeutic potential of targeting Tfr/Tfh cell balance by low-dose-IL-2 in active SLE: a post hoc analysis from a double-blind RCT study
Miao Miao, Xian Xiao, Jiayi Tian, Yunzhi Zhufeng, Ruiling Feng, Ruijun Zhang, Jiali Chen, Xiaoying Zhang, Bo Huang, Yuebo Jin, Xiaolin Sun, Jing He, Zhanguo Li
Clinical, laboratory, and genetic markers for the development or presence of psoriatic arthritis in psoriasis patients: a systematic review
Michelle L. M. Mulder, Tamara W. van Hal, Mark H. Wenink, Hans J. P. M. Koenen, Frank H. J. van den Hoogen, Elke M. G. J. de Jong, Juul M. P. A. van den Reek, Johanna E. Vriezekolk
Predictors of unacceptable pain with and without low inflammation over 5 years in early rheumatoid arthritis—an inception cohort study
Anna Eberhard, Stefan Bergman, Thomas Mandl, Tor Olofsson, Maria Rydholm, Lennart Jacobsson, Carl Turesson
Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective multicenter US cohort
Sara Jaafar, Alain Lescoat, Suiyuan Huang, Jessica Gordon, Monique Hinchcliff, Ami A. Shah, Shervin Assassi, Robyn Domsic, Elana J. Bernstein, Virginia Steen, Sabrina Elliott, Faye Hant, Flavia V. Castelino, Victoria K. Shanmugam, Chase Correia, John Varga, Vivek Nagaraja, David Roofeh, Tracy Frech, Dinesh Khanna
Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production
Ya-Chiao Hu, I-Jung Tsai, Hui-Yao Hsu, Bor-Luen Chiang, Yao-Hsu Yang
Biomechanical stress in the context of competitive sports training triggers enthesitis
David Simon, Arnd Kleyer, Sara Bayat, Johannes Knitza, Larissa Valor-Mendez, Marina Schweiger, Georg Schett, Koray Tascilar, Axel J. Hueber
The effect of a 24-week training focused on activities of daily living, muscle strengthening, and stability in idiopathic inflammatory myopathies: a monocentric controlled study with follow-up
Maja Špiritović, Barbora Heřmánková, Sabína Oreská, Hana Štorkánová, Olga Růžičková, Lucia Vernerová, Martin Klein, Kateřina Kubínová, Hana Šmucrová, Adéla Rathouská, Petr Česák, Martin Komarc, Václav Bunc, Karel Pavelka, Ladislav Šenolt, Heřman Mann, Jiří Vencovský, Michal Tomčík
Handwork vs machine: a comparison of rheumatoid arthritis patient populations as identified from EHR free-text by diagnosis extraction through machine-learning or traditional criteria-based chart review
T. D. Maarseveen, M. P. Maurits, E. Niemantsverdriet, A. H. M. van der Helm-van Mil, T. W. J. Huizinga, R. Knevel
Antiphospholipid antibodies and anticoagulant therapy: capillaroscopic findings
Giorgia Ferrari, Emanuele Gotelli, Sabrina Paolino, Giampaola Pesce, Luca Nanni, Barbara Maria Colombo, Greta Pacini, Carlotta Schenone, Carmen Pizzorni, Alberto Sulli, Vanessa Smith, Maurizio Cutolo
Effectiveness of bazedoxifene in preventing glucocorticoid-induced bone loss in rheumatoid arthritis patients
Soo-Kyung Cho, Hyoungyoung Kim, Jiyoung Lee, Eunwoo Nam, Seunghun Lee, Yun Young Choi, Yoon-Kyoung Sung
Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis
Jin Kyun Park, Sehui Shon, Hyun Jung Yoo, Dong-Hyeon Suh, Daekwon Bae, Jieun Shin, Jae Hyun Jun, Nina Ha, Hyeseung Song, Young Il Choi, Thomas Pap, Yeong Wook Song
Machine learning model for identifying important clinical features for predicting remission in patients with rheumatoid arthritis treated with biologics
Bon San Koo, Seongho Eun, Kichul Shin, Hyemin Yoon, Chaelin Hong, Do-Hoon Kim, Seokchan Hong, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Ji Seon Oh
The expansion of activated naive DNA autoreactive B cells and its association with disease activity in systemic lupus erythematosus patients
Kittikorn Wangriatisak, Chokchai Thanadetsuntorn, Thamonwan Krittayapoositpot, Chaniya Leepiyasakulchai, Thanitta Suangtamai, Pintip Ngamjanyaporn, Ladawan Khowawisetsut, Prasong Khaenam, Chavachol Setthaudom, Prapaporn Pisitkun, Patchanee Chootong
Influence of glucocorticoid treatment on trabecular bone score and bone remodeling regulators in early rheumatoid arthritis
Addolorata Corrado, Cinzia Rotondo, Angiola Mele, Daniela Cici, Nicola Maruotti, Eliana Sanpaolo, Ripalta Colia, Francesco Paolo Cantatore
Implementing an automated monitoring process in a digital, longitudinal observational cohort study
Lisa Lindner, Anja Weiß, Andreas Reich, Siegfried Kindler, Frank Behrens, Jürgen Braun, Joachim Listing, Georg Schett, Joachim Sieper, Anja Strangfeld, Anne C. Regierer
Switching from TNFα inhibitor to tacrolimus as maintenance therapy in rheumatoid arthritis after achieving low disease activity with TNFα inhibitors and methotrexate: 24-week result from a non-randomized, prospective, active-controlled trial
Sang Youn Jung, Jung Hee Koh, Ki-Jo Kim, Yong-Wook Park, Hyung-In Yang, Sung Jae Choi, Jisoo Lee, Chan-Bum Choi, Wan-Uk Kim
Identification and prediction of difficult-to-treat rheumatoid arthritis patients in structured and unstructured routine care data: results from a hackathon
Marianne A. Messelink, Nadia M. T. Roodenrijs, Bram van Es, Cornelia A. R. Hulsbergen-Veelken, Sebastiaan Jong, L. Malin Overmars, Leon C. Reteig, Sander C. Tan, Tjebbe Tauber, Jacob M. van Laar, Paco M. J. Welsing, Saskia Haitjema
Sonographic estimation of monosodium urate burden predicts the fulfillment of the 2016 remission criteria for gout: a 12-month study
Edoardo Cipolletta, Jacopo Di Battista, Marco Di Carlo, Andrea Di Matteo, Fausto Salaffi, Walter Grassi, Emilio Filippucci
Circulating microRNA alternations in primary hyperuricemia and gout
Jana Bohatá, Veronika Horváthová, Markéta Pavlíková, Blanka Stibůrková
Altered skeletal muscle metabolic pathways, age, systemic inflammation, and low cardiorespiratory fitness associate with improvements in disease activity following high-intensity interval training in persons with rheumatoid arthritis
Brian J. Andonian, Andrew Johannemann, Monica J. Hubal, David M. Pober, Alec Koss, William E. Kraus, David B. Bartlett, Kim M. Huffman
Incidence and predictors of COVID-19 and flares in patients with rare autoimmune diseases: a systematic survey and serological study at a national reference center in France
Renaud Felten, Marc Scherlinger, Aurélien Guffroy, Vincent Poindron, Alain Meyer, Margherita Giannini, Anne-Sophie Korganow, Christelle Sordet, Emmanuel Chatelus, Rose-Marie Javier, Aurore Meyer, Luc Pijnenburg, Jean-François Kleinmann, Jacques-Eric Gottenberg, Jean Sibilia, Thierry Martin, Laurent Arnaud
Plasma interferon-alpha is associated with double-positivity for autoantibodies but is not a predictor of remission in early rheumatoid arthritis—a spin-off study of the NORD-STAR randomized clinical trial
Marit Stockfelt, Anna-Carin Lundell, Merete Lund Hetland, Mikkel Østergaard, Till Uhlig, Marte Schrumpf Heiberg, Espen A. Haavardsholm, Michael T. Nurmohamed, Jon Lampa, Dan Nordström, Kim Hørslev Petersen, Bjorn Gudbjornsson, Gerdur Gröndal, Jonathan Aldridge, Kerstin Andersson, Kaj Blennow, Henrik Zetterberg, Ronald van Vollenhoven, Anna Rudin
Guselkumab demonstrated an independent treatment effect in reducing fatigue after adjustment for clinical response—results from two phase 3 clinical trials of 1120 patients with active psoriatic arthritis
Proton Rahman, Philip J. Mease, Philip S. Helliwell, Atul Deodhar, Laure Gossec, Arthur Kavanaugh, Alexa P. Kollmeier, Elizabeth C. Hsia, Bei Zhou, Xiwu Lin, May Shawi, Chetan S. Karyekar, Chenglong Han
Disease course following High Disease Activity Status revealed patterns in SLE
Alberta Hoi, Rachel Koelmeyer, Julie Bonin, Ying Sun, Amy Kao, Oliver Gunther, Hieu T. Nim, Eric Morand
Incidence of anterior uveitis in patients with axial spondyloarthritis treated with anti-TNF or anti-IL17A: a systematic review, a pairwise and network meta-analysis of randomized controlled trials
Damien Roche, Martin Badard, Laurent Boyer, Pierre Lafforgue, Thao Pham
Effects of a low-dose IL-2 treatment in HLA-B27 transgenic rat model of spondyloarthritis
L. M. Araujo, Q. Jouhault, I. Fert, I. Bouiller, G. Chiocchia, M. Breban
Altered circulating CCR6+and CXCR3+ T cell subsets are associated with poor renal prognosis in MPO-ANCA-associated vasculitis
Zhonghua Liao, Jiale Tang, Liying Luo, Shuanglinzi Deng, Lisa Luo, Fangyuan Wang, Xiangning Yuan, Xinyue Hu, Juntao Feng, Xiaozhao Li
Comment on “Urinary sodium-to-potassium ratio associates with hypertension and current disease activity in patients with rheumatoid arthritis: a cross-sectional study”: authors’ reply
Hiroto Minamino, Masao Katsushima, Yoshihito Fujita, Motomu Hashimoto
Clinical characteristics, imaging phenotypes and events free survival in Takayasu arteritis patients with hypertension
Sun Ying, Wu Sifan, Wang Yujiao, Chen Rongyi, Huang Qingrong, Ma Lili, Chen Huiyong, Jiang Lindi
Real-world comparative effectiveness and safety of tofacitinib and baricitinib in patients with rheumatoid arthritis
Naoki Iwamoto, Shuntaro Sato, Shota Kurushima, Toru Michitsuji, Shinya Nishihata, Momoko Okamoto, Yoshika Tsuji, Yushiro Endo, Toshimasa Shimizu, Remi Sumiyoshi, Takahisa Suzuki, Akitomo Okada, Tomohiro Koga, Shin-ya Kawashiri, Keita Fujikawa, Takashi Igawa, Toshiyuki Aramaki, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Akinari Mizokami, Tomoki Origuchi, Yukitaka Ueki, Katsumi Eguchi, Atsushi Kawakami
The lungs were on fire: a pilot study of 18F-FDG PET/CT in idiopathic-inflammatory-myopathy-related interstitial lung disease
Junyu Liang, Heng Cao, Yinuo Liu, Bingjue Ye, Yiduo Sun, Yini Ke, Ye He, Bei Xu, Jin Lin
Differential impacts of TNFα inhibitors on the transcriptome of Th cells
Ching-Huang Ho, Andrea A. Silva, Beverly Tomita, Hui-Ying Weng, I-Cheng Ho
Differences in oxylipin profile in psoriasis versus psoriatic arthritis
Roxana Coras, Arthur Kavanaugh, Angela Kluzniak, Dustina Holt, Amy Weilgosz, Armando Aaron, Oswald Quehenberger, Christopher Ritchlin, Monica Guma
Higher levels of anti-phosphorylcholine autoantibodies in early rheumatoid arthritis indicate lower risk of incident cardiovascular events
Sofia Ajeganova, Maria L. E. Andersson, Johan Frostegård, Ingiäld Hafström
Urate-induced epigenetic modifications in myeloid cells
M. Badii, O. I. Gaal, M. C. Cleophas, V. Klück, R. Davar, E. Habibi, S. T. Keating, B. Novakovic, M. M. Helsen, N. Dalbeth, L. K. Stamp, D. Macartney-Coxson, A. J. Phipps-Green, H. G. Stunnenberg, C. A. Dinarello, T. R. Merriman, M. G. Netea, T. O. Crişan, L. A. B. Joosten
Distinct patterns of disease activity over time in patients with active SLE revealed using latent class trajectory models
John A. Reynolds, Jennifer Prattley, Nophar Geifman, Mark Lunt, Caroline Gordon, Ian N. Bruce
An open-label study to evaluate biomarkers and safety in systemic sclerosis patients treated with paquinimod
Roger Hesselstrand, Jörg H. W. Distler, Gabriela Riemekasten, Dirk M. Wuttge, Marie Törngren, Helén C. Nyhlén, Fredrik Andersson, Helena Eriksson, Birgitta Sparre, Helén Tuvesson, Oliver Distler
Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity
Maurizio Cutolo, Emanuele Gotelli, Paola Montagna, Samuele Tardito, Sabrina Paolino, Carmen Pizzorni, Alberto Sulli, Vanessa Smith, Stefano Soldano
Do biologic therapies reduce aortic inflammation in rheumatoid arthritis patients?
D. A. M. Thuy Trang, Koichi Okamura, Takahito Suto, Hideo Sakane, Yukio Yonemoto, Takahito Nakajima, Yoshito Tsushima, Hirotaka Chikuda
Spinning straw into gold: description of a disruptive rheumatology research platform inspired by the COVID-19 pandemic
L. Boekel, F. Hooijberg, E. H. Vogelzang, P. L. Klarenbeek, W. H. Bos, S. W. Tas, G. J. Wolbink
Trabecular bone texture analysis of conventional radiographs in the assessment of knee osteoarthritis: review and viewpoint
Ahmad Almhdie-Imjabbar, Pawel Podsiadlo, Richard Ljuhar, Rachid Jennane, Khac-Lan Nguyen, Hechmi Toumi, Simo Saarakkala, Eric Lespessailles
Is tea consumption associated with reduction of risk of rheumatoid arthritis? A Swedish case-control study
Helga Westerlind, Ida Palmqvist, Saedis Saevarsdottir, Lars Alfredsson, Lars Klareskog, Daniela Di Giuseppe
Symptoms in first-degree relatives of patients with rheumatoid arthritis: evaluation of cross-sectional data from the symptoms in persons at risk of rheumatoid arthritis (SPARRA) questionnaire in the PRe-clinical EValuation of Novel Targets in RA (PREVeNT-RA) Cohort
R. E. Costello, J. H. Humphreys, J. C. Sergeant, M. Haris, F. Stirling, K. Raza, D. van Schaardenburg, Ian N. Bruce
First exposure to rituximab is associated to high rate of anti-drug antibodies in systemic lupus erythematosus but not in ANCA-associated vasculitis
Francesca Faustini, Nicky Dunn, Nastya Kharlamova, Malin Ryner, Annette Bruchfeld, Vivianne Malmström, Anna Fogdell-Hahn, Iva Gunnarsson
The role of lung ultrasound B-lines and serum KL-6 in the screening and follow-up of rheumatoid arthritis patients for an identification of interstitial lung disease: review of the literature, proposal for a preliminary algorithm, and clinical application to cases
Yukai Wang, Shaoqi Chen, Shaoyu Zheng, Jianqun Lin, Shijian Hu, Jinghua Zhuang, Qisheng Lin, Xuezhen Xie, Kedi Zheng, Weijin Zhang, Guangzhou Du, Guohong Zhang, Anna-Maria Hoffmann-Vold, Marco Matucci-Cerinic, Daniel E. Furst
Blocking Jak/STAT signalling using tofacitinib inhibits angiogenesis in experimental arthritis
Paola Di Benedetto, Piero Ruscitti, Onorina Berardicurti, Noemi Panzera, Nicolò Grazia, Mauro Di Vito Nolfi, Barbara Di Francesco, Luca Navarini, Antonio Maurizi, Nadia Rucci, Anna Maria Teti, Francesca Zazzeroni, Giuliana Guggino, Francesco Ciccia, Vincenza Dolo, Edoardo Alesse, Paola Cipriani, Roberto Giacomelli
Pathogenic roles and therapeutic potential of the CCL8–CCR8 axis in a murine model of IgG4-related sialadenitis
Fumika Honda, Hiroto Tsuboi, Yuko Ono, Saori Abe, Hiroyuki Takahashi, Kiyoaki Ito, Kazunori Yamada, Mitsuhiro Kawano, Yuya Kondo, Kenichi Asano, Masato Tanaka, Marie Malissen, Bernard Malissen, Isao Matsumoto, Takayuki Sumida
Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants
Evelyn Houtman, Margo Tuerlings, Janne Riechelman, Eka H. E. D. Suchiman, Robert J. P. van der Wal, Rob G. H. H. Nelissen, Hailiang Mei, Yolande F. M. Ramos, Rodrigo Coutinho de Almeida, Ingrid Meulenbelt
S100A8/A9 is not essential for the development of inflammation and joint pathology in interleukin-1 receptor antagonist knockout mice
Irene Di Ceglie, Peter L. E. M. van Lent, Edwin J. W. Geven, Marije I. Koenders, Arjen B. Blom, Thomas Vogl, Johannes Roth, Martijn H. J. van den Bosch
Diagnosis of early stage knee osteoarthritis based on early clinical course: data from the CHECK cohort
Qiuke Wang, Jos Runhaar, Margreet Kloppenburg, Maarten Boers, Johannes W. J. Bijlsma, Sita M. A. Bierma-Zeinstra, N. E. Aerts-Lankhorst, R. Agricola, A. N. Bastick, R. D. W. van Bentveld, P. J. van den Berg, J. Bijsterbosch, A. de Boer, M. Boers, A. M. Bohnen, A. E. R. C. H. Boonen, P. K. Bos, T. A. E. J. Boymans, H. P. Breedveldt-Boer, R. W. Brouwer, J. W. Colaris, J. Damen, G. Elshout, P. J. Emans, W. T. M. Enthoven, E. J. M. Frölke, R. Glijsteen, H. J. C. van der Heide, A. M. Huisman, R. D. van Ingen, M. L. Jacobs, R. P. A. Janssen, P. M. Kevenaar, M. A. van Koningsbrugge, P. Krastman, N. O. Kuchuk, M. L. A. Landsmeer, W. F. Lems, H. M. J. van der Linden, R. van Linschoten, E. A. M. Mahler, B. L. van Meer, D. E. Meuffels, W. H. Noort-van der Laan, J. M. van Ochten, J. van Oldenrijk, G. H. J. Pols, T. M. Piscaer, J. B. M. Rijkels-Otters, N. Riyazi, J. M. Schellingerhout, H. J. Schers, B. W. V. Schouten, G. F. Snijders, W. E. van Spil, S. A. G. Stitzinger, J. J. Tolk, Y. D. M. van Trier, M. Vis, V. M. I. Voorbrood, B. C. de Vos, A. de Vries
Hyaluronic acid synthesis, degradation, and crosslinking in equine osteoarthritis: TNF-α-TSG-6-mediated HC-HA formation
Diana C. Fasanello, Jin Su, Siyu Deng, Rose Yin, Marshall J. Colville, Joshua M. Berenson, Carolyn M. Kelly, Heather Freer, Alicia Rollins, Bettina Wagner, Felipe Rivas, Adam R. Hall, Elaheh Rahbar, Paul L. DeAngelis, Matthew J. Paszek, Heidi L. Reesink
Mediterranean diet in axial spondyloarthritis: an observational study in an Italian monocentric cohort
Francesca Ometto, Augusta Ortolan, Davide Farber, Mariagrazia Lorenzin, Giulia Dellamaria, Giacomo Cozzi, Marta Favero, Romina Valentini, Andrea Doria, Roberta Ramonda
Differences and similarities in clinical and functional responses among patients receiving tofacitinib monotherapy, tofacitinib plus methotrexate, and adalimumab plus methotrexate: a post hoc analysis of data from ORAL Strategy
Tsutomu Takeuchi, Roy Fleischmann, Noriko Iikuni, Harry Shi, Koshika Soma, Jerome Paulissen, Tomohiro Hirose, Josef S. Smolen
Patient- and physician-reported outcomes from two phase 3 randomized studies (RAJ3 and RAJ4) of peficitinib (ASP015K) in Asian patients with rheumatoid arthritis
Yoshiya Tanaka, Tsutomu Takeuchi, Hiroyuki Izutsu, Yuichiro Kaneko, Daisuke Kato, Musashi Fukuda, Mitsuhiro Rokuda, Neil M. Schultz
Incidence and severity of G6PI-induced arthritis are not increased in genetically distinct mouse strains upon aging
Nico Andreas, Sylvia Müller, Nicole Templin, Paul M. Jordan, Harald Schuhwerk, Michael Müller, Jana Gerstmeier, Laura Miek, Saskia Andreas, Oliver Werz, Thomas Kamradt
Microarray-based analysis of renal complement components reveals a therapeutic target for lupus nephritis
Tao Liu, Mingyue Yang, Ying Xia, Chuan Jiang, Chenxu Li, Zhenyu Jiang, Xiaosong Wang
Epidemiology and treatment of Behçet’s disease in the USA: insights from the Rheumatology Informatics System for Effectiveness (RISE) Registry with a comparison with other published cohorts from endemic regions
Nevin Hammam, Jing Li, Michael Evans, Julia L. Kay, Zara Izadi, Christine Anastasiou, Milena A. Gianfrancesco, Jinoos Yazdany, Gabriela Schmajuk
Accelerated osteoarthritis in women with polycystic ovary syndrome: a prospective nationwide registry-based cohort study
Stefan Kluzek, Katrine Hass Rubin, Maria Sanchez-Santos, Mary S. O’Hanlon, Marianne Andersen, Dorte Glintborg, Bo Abrahamsen
A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis
Louie C. Alexander Jr, Grant McHorse, Janet L. Huebner, Anne-Christine Bay-Jensen, Morten A. Karsdal, Virginia B. Kraus
Comparison of properties determined using electromechanical assessment (Arthro-BST™) with macroscopic and histological properties in symptomatic human articular cartilage of the hip
Taku Ukai, Masato Sato, Shiho Wasai, Takumi Takahashi, Haruka Omura, Masahiko Watanabe
Impact of the HLA-DRB1 shared epitope on responses to treatment with tofacitinib or abatacept in patients with rheumatoid arthritis
Wataru Hirose, Masayoshi Harigai, Koichi Amano, Toshihiko Hidaka, Kenji Itoh, Kazutoshi Aoki, Masahiro Nakashima, Hayato Nagasawa, Yukiko Komano, Toshihiro Nanki, Yuji Akiyama, Souichirou Ando, Yayoi Hashiba, Motohide Kaneko, Mitsuhiro Kawagoe, Tsuneo Kondo, Kazuyoshi Kubo, Ikuko Masuda, Mitsuyo Matsumoto, Yusuke Okada, Akiko Shibata, Kimihiro Suzuki, Ko Takamatsu, Hirofumi Takei
The prevalence of oral mucosal lesions and related factors in systemic lupus erythematosus patients
Mayssoun Kudsi, Louei Darjazini Nahas, Rama Alsawah, Ahmad Hamsho, Abdullah Omar
Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load
Sanne Reijm, Theresa Kissel, Gerrie Stoeken-Rijsbergen, Linda M. Slot, Corrie M. Wortel, Hugo J. van Dooren, Nivine E. W. Levarht, Arieke S. B. Kampstra, Veerle F. A. M. Derksen, Pleuni Ooijevaar-de Heer, Holger Bang, Jan W. Drijfhout, Leendert A. Trouw, Tom W. J. Huizinga, Theo Rispens, Hans U. Scherer, René E. M. Toes
Secukinumab in non-radiographic axial spondyloarthritis: subgroup analysis based on key baseline characteristics from a randomized phase III study, PREVENT
Jürgen Braun, Ricardo Blanco, Helena Marzo-Ortega, Lianne S. Gensler, Filip van den Bosch, Stephen Hall, Hideto Kameda, Denis Poddubnyy, Marleen van de Sande, Anna S. Wiksten, Brian O. Porter, Abhijit Shete, Hanno B. Richards, Sibylle Haemmerle, Atul Deodhar
High incidence and mortality of Pneumocystis jirovecii infection in anti-MDA5-antibody-positive dermatomyositis: experience from a single center
Linlin Huang, Qiong Fu, Yan Ye, Yanwei Lin, Qingran Yan, Sheng Chen
Accuracy and usability of a diagnostic decision support system in the diagnosis of three representative rheumatic diseases: a randomized controlled trial among medical students
Johannes Knitza, Koray Tascilar, Eva Gruber, Hannah Kaletta, Melanie Hagen, Anna-Maria Liphardt, Hannah Schenker, Martin Krusche, Jochen Wacker, Arnd Kleyer, David Simon, Nicolas Vuillerme, Georg Schett, Axel J. Hueber
The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis
Emma Derrett-Smith, Kristina E. N. Clark, Xu Shiwen, David J. Abraham, Rachel K. Hoyles, Olivier Lacombe, Pierre Broqua, Jean Louis Junien, Irena Konstantinova, Voon H. Ong, Christopher P. Denton
Prognostic factors of total hip replacement during a 2-year period in participants enrolled in supervised education and exercise therapy: a prognostic study of 3657 participants with hip osteoarthritis
Stine Clausen, Jan Hartvigsen, Eleanor Boyle, Ewa M. Roos, Dorte Thalund Grønne, Martin Thomsen Ernst, Bodil Arnbak, Søren T. Skou
Treatment patterns in rheumatoid arthritis patients newly initiated on biologic and conventional synthetic disease-modifying antirheumatic drug therapy and enrolled in a North American clinical registry
Philip J. Mease, Scott Stryker, Mei Liu, Bob Salim, Sabrina Rebello, Mahdi Gharaibeh, David H. Collier
Correction to: Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats
Qi Sun, Fa-Ming Tian, Fang Liu, Jia-Kang Fang, Yun-Peng Hu, Qiang-Qiang Lian, Zhuang Zhou, Liu Zhang
HLA-B52 allele in giant cell arteritis may indicate diffuse large-vessel vasculitis formation: a retrospective study
Kazuo Kushimoto, Masahiro Ayano, Keisuke Nishimura, Miki Nakano, Yasutaka Kimoto, Hiroki Mitoma, Nobuyuki Ono, Yojiro Arinobu, Koichi Akashi, Takahiko Horiuchi, Hiroaki Niiro
The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual “window of treatment success” in RA patients
Bianka Marklein, Madeleine Jenning, Zoltán Konthur, Thomas Häupl, Franziska Welzel, Ute Nonhoff, Sylvia Krobitsch, Debbie M. Mulder, Marije I. Koenders, Vijay Joshua, Andrew P. Cope, Mark J. Shlomchik, Hans-Joachim Anders, Gerd R. Burmester, Aase Hensvold, Anca I. Catrina, Johan Rönnelid, Günter Steiner, Karl Skriner
Gut microbiota mediated the therapeutic efficacies and the side effects of prednisone in the treatment of MRL/lpr mice
Mingzhu Wang, Zhengyang Zhu, Xiaoying Lin, Haichang Li, Chengping Wen, Jie Bao, Zhixing He
Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration
Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid
Study TPX-100-5: intra-articular TPX-100 significantly delays pathological bone shape change and stabilizes cartilage in moderate to severe bilateral knee OA
Dawn McGuire, Michael Bowes, Alan Brett, Neil A. Segal, Meghan Miller, David Rosen, Yoshinari Kumagai
Isopsoralen ameliorates rheumatoid arthritis by targeting MIF
Yi Han, Jinguang Wang, Shufeng Li, Yi Li, Yongli Zhang, Ruojia Zhang, Yuang Zhang, Huancai Fan, Haojun Shi, Jihong Pan, Guanhua Song, Luna Ge, Lin Wang
Risk of rheumatoid arthritis diagnosis in statin users in a large nationwide US study
Madeline N. Peterson, Hayley J. Dykhoff, Cynthia S. Crowson, John M. Davis III, Lindsey R. Sangaralingham, Elena Myasoedova
HLA-DRB1 risk alleles for RA are associated with differential clinical responsiveness to abatacept and adalimumab: data from a head-to-head, randomized, single-blind study in autoantibody-positive early RA
William Rigby, Jane H. Buckner, S. Louis Bridges Jr, Marleen Nys, Sheng Gao, Martin Polinsky, Neelanjana Ray, Vivian Bykerk
Monocyte transcriptomes from patients with axial spondyloarthritis reveal dysregulated monocytopoiesis and a distinct inflammatory imprint
Fabian Karow, Biljana Smiljanovic, Joachim R. Grün, Denis Poddubnyy, Fabian Proft, Alice Talpin, Christophe Hue, Anne Boland, Jean-François Deleuze, Henri-Jean Garchon, Ilkay Ergenç, Ann-Sophie De Craemer, Ulrike Erben, Thomas Häupl, Dirk Elewaut, Maxime Breban, Andreas Grützkau, Uta Syrbe
Accelerated diastolic dysfunction in premenopausal women with rheumatoid arthritis
Gee Hee Kim, Yune-Jung Park
Long-term efficacy, safety, and immunogenicity of the adalimumab biosimilar, PF-06410293, in patients with rheumatoid arthritis after switching from reference adalimumab (Humira®) or continuing biosimilar therapy: week 52–92 data from a randomized, double-blind, phase 3 trial
Roy M. Fleischmann, Daniel F. Alvarez, Amy E. Bock, Carol Cronenberger, Ivana Vranic, Wuyan Zhang, Rieke Alten
Association of retroperitoneal fibrosis with malignancy and its outcomes
Sang Jin Lee, Jung Su Eun, Min Jung Kim, Yeong Wook Song, Young Mo Kang
Olfactory impairment in patients with primary Sjogren’s syndrome and its correlation with organ involvement and immunological abnormalities
Xue Xu, Linyu Geng, Chen Chen, Wentao Kong, Baojie Wen, Wei Kong, Siwen Chen, Huayong Zhang, Jun Liang, Lingyun Sun
Integrative analysis of genome-wide DNA methylation and single-nucleotide polymorphism identified ACSM5 as a suppressor of lumbar ligamentum flavum hypertrophy
Yanlin Cao, Yenan Zhan, Sujun Qiu, Zhong Chen, Kaiqin Gong, Songjia Ni, Yang Duan
Longitudinal analysis of the patient pathways to diagnosis of psoriatic arthritis
Alexis Ogdie, Martin Rozycki, Theresa Arndt, Cheng Shi, Nina Kim, Peter Hur
Rapamycin-induced hyperglycemia is associated with exacerbated age-related osteoarthritis
Dennis M. Minton, Christian J. Elliehausen, Martin A. Javors, Kelly S. Santangelo, Adam R. Konopka
Machine learning-based prediction model for responses of bDMARDs in patients with rheumatoid arthritis and ankylosing spondylitis
Seulkee Lee, Seonyoung Kang, Yeonghee Eun, Hong-Hee Won, Hyungjin Kim, Jaejoon Lee, Eun-Mi Koh, Hoon-Suk Cha
Correction to: The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual “window of treatment success” in RA patients
Bianka Marklein, Madeleine Jenning, Zoltán Konthur, Thomas Häupl, Franziska Welzel, Ute Nonhoff, Sylvia Krobitsch, Debbie M. Mulder, Marije I. Koenders, Vijay Joshua, Andrew P. Cope, Mark J. Shlomchik, Hans-Joachim Anders, Gerd R. Burmester, Aase Hensvold, Anca I. Catrina, Johan Rönnelid, Günter Steiner, Karl Skriner
Catastrophic adult-onset Still’s disease as a distinct life-threatening clinical subset: case–control study with dimension reduction analysis
Anaïs Wahbi, Benoît Tessoulin, Cédric Bretonnière, Julien Boileau, Dorothée Carpentier, Olivier Decaux, Laurence Fardet, Guillaume Geri, Pascal Godmer, Cécile Goujard, Hervé Maisonneuve, Arnaud Mari, Jacques Pouchot, Jean-Marc Ziza, Sophie Georgin-Lavialle, Mohamed Hamidou, Antoine Néel
Correlation of peripheral CD4+GranzB+CTLs with disease severity in patients with primary Sjögren’s syndrome
Qi Wang, Nan Che, Chengyin Lu, Xiaoxuan Sun, Yanyan Wang, Qiang Wang, Wenfeng Tan, Lanlan Zhou, Xiaojun Zhang, Dong Xu, Lei Gu, Miaojia Zhang
Radial BMD and serum CTX-I can predict the progression of carotid plaque in rheumatoid arthritis: a 3-year prospective cohort study
Seungwoo Han, Na-Ri Kim, Jong-Wan Kang, Jung-Su Eun, Young-Mo Kang
Multiomic study of skin, peripheral blood, and serum: is serum proteome a reflection of disease process at the end-organ level in systemic sclerosis?
Victor Farutin, Elma Kurtagic, Joël R. Pradines, Ishan Capila, Maureen D. Mayes, Minghua Wu, Anthony M. Manning, Shervin Assassi
Granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α in combination is a useful diagnostic biomarker to distinguish familial Mediterranean fever from sepsis
Tomohiro Koga, Kaori Furukawa, Kiyoshi Migita, Shimpei Morimoto, Toshimasa Shimizu, Shoichi Fukui, Masataka Umeda, Yushiro Endo, Remi Sumiyoshi, Shin-ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Tomoki Origuchi, Takahiro Maeda, Akihiro Yachie, Atsushi Kawakami
bFGF could be a biomarker of malignancy in RS3PE syndrome: an ambispective single-center cohort analysis of 51 patients
Yuzhou Gan, Yi Sun, Jiayang Jin, Yifan Wang, Jiali Chen, Yukchiu Chung, Xue Li, Hua Ye
A deep learning method for predicting knee osteoarthritis radiographic progression from MRI
Jean-Baptiste Schiratti, Rémy Dubois, Paul Herent, David Cahané, Jocelyn Dachary, Thomas Clozel, Gilles Wainrib, Florence Keime-Guibert, Agnes Lalande, Maria Pueyo, Romain Guillier, Christine Gabarroca, Philippe Moingeon
Correction to: Symptoms in first-degree relatives of patients with rheumatoid arthritis: evaluation of cross-sectional data from the symptoms in persons at risk of rheumatoid arthritis (SPARRA) questionnaire in the Preclinical EValuation of Novel Targets in RA (PREVeNT-RA) Cohort
R. E. Costello, J. H. Humphreys, J. C. Sergeant, M. Haris, F. Stirling, K. Raza, D. van Schaardenburg, Ian N. Bruce
Impact of systemic lupus erythematosus on the 5-year survival of critically ill septic patients
Hsin-Hua Chen, Hsian-Min Chen, Yi-Ming Chen, Yi-Hsing Chen, Ching-Heng Lin, Wen-Cheng Chao
Non-invasive monitoring of arthritis treatment response via targeting of tyrosine-phosphorylated annexin A2 in chondrocytes
Shaw-Wei D. Tsen, Luke E. Springer, Krishna Sharmah Gautam, Rui Tang, Kexian Liang, Gail Sudlow, Amir Kucharski, Christine T. N. Pham, Samuel Achilefu
The protein-protein interaction between connective tissue growth factor and annexin A2 is relevant to pannus formation in rheumatoid arthritis
Guoyu Yin, Chenglin Yang, Gan Wu, Xinxin Yu, Qingqing Tian, Daoxing Chen, Ben Cao, Lin Zhao, Nannan Xu, Shengwei Jin, Wei Zhang, Jianguang Wang
Increased radiographic progression of distal hand osteoarthritis occurring during biologic DMARD monotherapy for concomitant rheumatoid arthritis
C. A. Lechtenboehmer, T. Burkard, S. Reichenbach, U. A. Walker, A. M. Burden, T. Hügle
Cranial and extracranial giant cell arteritis do not have different HLA-DRB1 and HLA-B association in Caucasian individuals
Diana Prieto-Peña, Sara Remuzgo-Martínez, Belén Atienza-Mateo, Raquel López-Mejias, Miguel Á. González-Gay, Fernanda Genre, Javier Gonzalo Ocejo-Vinyals, Alejandro Muñoz Jiménez, Francisco Ortiz-Sanjuán, Susana Romero-Yuste, Clara Moriano, Eva Galíndez-Agirregoikoa, Itziar Calvo, Norberto Ortego-Centeno, Noelia Álvarez-Rivas, José A. Miranda-Filloy, Irene Llorente, Ricardo Blanco, Oreste Gualillo, Javier Martín, Ana Márquez, Santos Castañeda, Iván Ferraz-Amaro
Treatment response and several patient-reported outcomes are early determinants of future self-efficacy in rheumatoid arthritis
Michaël Doumen, Diederik De Cock, Sofia Pazmino, Delphine Bertrand, Johan Joly, René Westhovens, Patrick Verschueren
Increased risk of malignancy in patients with systemic lupus erythematosus: population-based cohort study in Korea
Jung-Yong Han, Hyoungyoung Kim, Sun-Young Jung, Eun Jin Jang, Soo-Kyung Cho, Yoon-Kyoung Sung
Hydroxychloroquine use is not associated with QTc length in a large cohort of SLE and RA patients
Elizabeth Park, Jon T. Giles, Thania Perez-Recio, Paloma Pina, Christopher Depender, Yevgeniya Gartshteyn, Anca D. Askanase, Joan Bathon, Laura Geraldino-Pardilla
Immunoprofiling of early, untreated rheumatoid arthritis using mass cytometry reveals an activated basophil subset inversely linked to ACPA status
H. Koppejan, M. Hameetman, G. Beyrend, V. van Unen, J. C. Kwekkeboom, A. H. van der Helm-van Mil, R. E. M. Toes, F. A. van Gaalen
Sustained microglial activation in the area postrema of collagen-induced arthritis mice
Takayuki Matsushita, Kazuhiro Otani, Yohsuke Oto, Yukari Takahashi, Daitaro Kurosaka, Fusao Kato
Predictors of long-term clinical response in patients with non-radiographic axial spondyloarthritis receiving certolizumab pegol
Walter P. Maksymowych, Thomas Kumke, Simone E. Auteri, Bengt Hoepken, Lars Bauer, Martin Rudwaleit
Treatments and outcomes in Chinese patients with serologically active clinically quiescent systemic lupus erythematosus: a retrospective observational study
Hong Huang, Lin Mu, Zhuoli Zhang, Dai Gao, Yanjie Hao, Wei Zhou
Correction to: Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration
Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid
Insulin-like growth factor-1 in articular cartilage repair for osteoarthritis treatment
Caining Wen, Limei Xu, Xiao Xu, Daping Wang, Yujie Liang, Li Duan
Baseline predictors of remission, pain and fatigue in rheumatoid arthritis: the TITRATE trial
Sook Yan Lee, Fowzia Ibrahim, Brian D. M. Tom, Elena Nikiphorou, Frances M. K. Williams, Heidi Lempp, David L. Scott
Lupus susceptibility region containing CTLA4 rs17268364 functionally reduces CTLA4 expression by binding EWSR1 and correlates IFN-α signature
Yuan-yuan Qi, Xin-yu Zhao, Xin-ran Liu, Yan-na Wang, Ya-ling Zhai, Xiao-xue Zhang, Xiao-yang Wang, Li-jie Zhang, Ya-fei Zhao, Yan Cui, Xiang-hui Ning, Xu-jie Zhou
Immune cell profiles in synovial fluid after anterior cruciate ligament and meniscus injuries
Sophia Y. Kim-Wang, Abigail G. Holt, Alyssa M. McGowan, Stephanie T. Danyluk, Adam P. Goode, Brian C. Lau, Alison P. Toth, Jocelyn R. Wittstein, Louis E. DeFrate, John S. Yi, Amy L. McNulty
First-year follow-up of children with chronic nonbacterial osteomyelitis—an analysis of the German National Pediatric Rheumatologic Database from 2009 to 2018
Christiane Reiser, Jens Klotsche, Anton Hospach, Rainer Berendes, Anja Schnabel, Annette F. Jansson, Markus Hufnagel, Nadine Grösch, Martina Niewerth, Kirsten Minden, Hermann Girschick
Correction to: Mediterranean diet in axial spondyloarthritis: an observational study in an Italian monocentric cohort
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