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Erschienen in: DNP - Der Neurologe & Psychiater 7-8/2017

31.07.2017 | Manische Episode | Fortbildung

Manisch-depressive Erkrankungen

Lithium in der Langzeittherapie der bipolaren Störung — was gibt es Neues?

verfasst von: Dr. med. univ. Johannes Petzold, Prof. Dr. med. Dr. rer. nat. Michael Bauer, PD Dr. med. habil. Emanuel Severus

Erschienen in: DNP – Die Neurologie & Psychiatrie | Ausgabe 7-8/2017

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Zusammenfassung

Den Stellenwert von Lithium als effektivstes Medikament in der Langzeitbehandlung bipolarer Erkrankungen bestätigen aktuelle Metaanalysen. Drei neuere Studien zeichnen nun ein differenziertes und auch kontrastierendes Bild im Vergleich zu atypischen Antipsychotika.
Literatur
1.
2.
Zurück zum Zitat Grunze H, Vieta E, Goodwin GM, Bowden C, Licht RW, Moller HJ, et al.: The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: update 2012 on the long-term treatment of bipolar disorder. World J Biol Psychiatry 2013; 14(3): 154–219.CrossRef Grunze H, Vieta E, Goodwin GM, Bowden C, Licht RW, Moller HJ, et al.: The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: update 2012 on the long-term treatment of bipolar disorder. World J Biol Psychiatry 2013; 14(3): 154–219.CrossRef
3.
Zurück zum Zitat Kendall T, Morriss R, Mayo-Wilson E, Marcus E: Assessment and management of bipolar disorder: summary of updated NICE guidance. BMJ 2014; 349: g5673.CrossRefPubMed Kendall T, Morriss R, Mayo-Wilson E, Marcus E: Assessment and management of bipolar disorder: summary of updated NICE guidance. BMJ 2014; 349: g5673.CrossRefPubMed
4.
Zurück zum Zitat Miura T, Noma H, Furukawa TA, Mitsuyasu H, Tanaka S, Stockton S, et al.: Comparative efficacy and tolerability of pharmacological treatments in the maintenance treatment of bipolar disorder: a systematic review and network meta-analysis. Lancet Psychiatry 2014; 1(5): 351–9.CrossRefPubMed Miura T, Noma H, Furukawa TA, Mitsuyasu H, Tanaka S, Stockton S, et al.: Comparative efficacy and tolerability of pharmacological treatments in the maintenance treatment of bipolar disorder: a systematic review and network meta-analysis. Lancet Psychiatry 2014; 1(5): 351–9.CrossRefPubMed
5.
Zurück zum Zitat Severus E, Taylor MJ, Sauer C, Pfennig A, Ritter P, Bauer M, et al.: Lithium for prevention of mood episodes in bipolar disorders: systematic review and meta-analysis. Int J Bipolar Disord 2014; 2: 15.CrossRefPubMedPubMedCentral Severus E, Taylor MJ, Sauer C, Pfennig A, Ritter P, Bauer M, et al.: Lithium for prevention of mood episodes in bipolar disorders: systematic review and meta-analysis. Int J Bipolar Disord 2014; 2: 15.CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Berk M, Daglas R, Dandash O, Yucel M, Henry L, Hallam K, et al.: Quetiapine v. lithium in the maintenance phase following a first episode of mania: randomised controlled trial. Br J Psychiatry 2017. Berk M, Daglas R, Dandash O, Yucel M, Henry L, Hallam K, et al.: Quetiapine v. lithium in the maintenance phase following a first episode of mania: randomised controlled trial. Br J Psychiatry 2017.
7.
Zurück zum Zitat Hayes JF, Marston L, Walters K, Geddes JR, King M, Osborn DP: Lithium vs. valproate vs. olanzapine vs. quetiapine as maintenance monotherapy for bipolar disorder: a population-based UK cohort study using electronic health records. World Psychiatry 2016; 15(1): 53–8.CrossRefPubMedPubMedCentral Hayes JF, Marston L, Walters K, Geddes JR, King M, Osborn DP: Lithium vs. valproate vs. olanzapine vs. quetiapine as maintenance monotherapy for bipolar disorder: a population-based UK cohort study using electronic health records. World Psychiatry 2016; 15(1): 53–8.CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Nierenberg AA, McElroy SL, Friedman ES, Ketter TA, Shelton RC, Deckersbach T, et al.: Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness): a pragmatic 6-month trial of lithium versus quetiapine for bipolar disorder. J Clin Psychiatry 2016; 77(1): 90–9.CrossRefPubMed Nierenberg AA, McElroy SL, Friedman ES, Ketter TA, Shelton RC, Deckersbach T, et al.: Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness): a pragmatic 6-month trial of lithium versus quetiapine for bipolar disorder. J Clin Psychiatry 2016; 77(1): 90–9.CrossRefPubMed
9.
Zurück zum Zitat Tohen M, Frank E, Bowden CL, Colom F, Ghaemi SN, Yatham LN, et al.: The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders. Bipolar Disord 2009; 11(5): 453–73.CrossRefPubMed Tohen M, Frank E, Bowden CL, Colom F, Ghaemi SN, Yatham LN, et al.: The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders. Bipolar Disord 2009; 11(5): 453–73.CrossRefPubMed
10.
Zurück zum Zitat Lewitzka U, Severus E, Bauer R, Ritter P, Muller-Oerlinghausen B, Bauer M: The suicide prevention effect of lithium: more than 20 years of evidence-a narrative review. Int J Bipolar Disord 2015; 3(1): 32.CrossRefPubMed Lewitzka U, Severus E, Bauer R, Ritter P, Muller-Oerlinghausen B, Bauer M: The suicide prevention effect of lithium: more than 20 years of evidence-a narrative review. Int J Bipolar Disord 2015; 3(1): 32.CrossRefPubMed
11.
Zurück zum Zitat Licht RW, Severus E: Letter to the editor: is it valid to break down results from long-term trials in bipolar disorder by polarity of relapses? Int J Bipolar Disord 2014; 2(1): 8.CrossRefPubMedPubMedCentral Licht RW, Severus E: Letter to the editor: is it valid to break down results from long-term trials in bipolar disorder by polarity of relapses? Int J Bipolar Disord 2014; 2(1): 8.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Weisler RH, Nolen WA, Neijber A, Hellqvist A, Paulsson B: Continuation of quetiapine versus switching to placebo or lithium for maintenance treatment of bipolar I disorder (Trial 144: a randomized controlled study). J Clin Psychiatry 2011; 72(11): 1452–64.CrossRefPubMed Weisler RH, Nolen WA, Neijber A, Hellqvist A, Paulsson B: Continuation of quetiapine versus switching to placebo or lithium for maintenance treatment of bipolar I disorder (Trial 144: a randomized controlled study). J Clin Psychiatry 2011; 72(11): 1452–64.CrossRefPubMed
13.
Zurück zum Zitat Cipriani A, Barbui C, Rendell J, Geddes JR: Clinical and regulatory implications of active run-in phases in long-term studies for bipolar disorder. Acta Psychiatr Scand 2014; 129(5): 328–42.CrossRefPubMed Cipriani A, Barbui C, Rendell J, Geddes JR: Clinical and regulatory implications of active run-in phases in long-term studies for bipolar disorder. Acta Psychiatr Scand 2014; 129(5): 328–42.CrossRefPubMed
14.
Zurück zum Zitat Severus WE, Lipkovich IA, Licht RW, Young AH, Greil W, Ketter T, et al.: In search of optimal lithium levels and olanzapine doses in the long-term treatment of bipolar I disorder. A post-hoc analysis of the maintenance study by Tohen et al. 2005. Eur Psychiatry 2010; 25(8): 443–9.CrossRefPubMed Severus WE, Lipkovich IA, Licht RW, Young AH, Greil W, Ketter T, et al.: In search of optimal lithium levels and olanzapine doses in the long-term treatment of bipolar I disorder. A post-hoc analysis of the maintenance study by Tohen et al. 2005. Eur Psychiatry 2010; 25(8): 443–9.CrossRefPubMed
15.
Zurück zum Zitat Bourin MS, Severus E, Schronen JP, Gass P, Szamosi J, Eriksson H, et al.: Lithium as add-on to quetiapine XR in adult patients with acute mania: a 6-week, multicenter, double-blind, randomized, placebo-controlled study. Int J Bipolar Disord 2014; 2: 14.CrossRefPubMedPubMedCentral Bourin MS, Severus E, Schronen JP, Gass P, Szamosi J, Eriksson H, et al.: Lithium as add-on to quetiapine XR in adult patients with acute mania: a 6-week, multicenter, double-blind, randomized, placebo-controlled study. Int J Bipolar Disord 2014; 2: 14.CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Conell J, Lewitzka U, Ritter P, Severus E, Pilhatsch M, Pfennig A, et al.: [Is there an increased risk for renal tumors during long-term treatment with lithium?]. Nervenarzt 2015; 86(9): 1157–61.CrossRefPubMed Conell J, Lewitzka U, Ritter P, Severus E, Pilhatsch M, Pfennig A, et al.: [Is there an increased risk for renal tumors during long-term treatment with lithium?]. Nervenarzt 2015; 86(9): 1157–61.CrossRefPubMed
17.
Zurück zum Zitat Kessing LV, Gerds TA, Feldt-Rasmussen B, Andersen PK, Licht RW: Use of Lithium and Anticonvulsants and the Rate of Chronic Kidney Disease: A Nationwide Population-Based Study. JAMA Psychiatry 2015; 72(12): 1182–91.CrossRefPubMed Kessing LV, Gerds TA, Feldt-Rasmussen B, Andersen PK, Licht RW: Use of Lithium and Anticonvulsants and the Rate of Chronic Kidney Disease: A Nationwide Population-Based Study. JAMA Psychiatry 2015; 72(12): 1182–91.CrossRefPubMed
18.
Zurück zum Zitat Kessing LV, Gerds TA, Feldt-Rasmussen B, Andersen PK, Licht RW: Lithium and renal and upper urinary tract tumors - results from a nationwide population-based study. Bipolar Disord 2015; 17(8): 805–13.CrossRefPubMed Kessing LV, Gerds TA, Feldt-Rasmussen B, Andersen PK, Licht RW: Lithium and renal and upper urinary tract tumors - results from a nationwide population-based study. Bipolar Disord 2015; 17(8): 805–13.CrossRefPubMed
Metadaten
Titel
Manisch-depressive Erkrankungen
Lithium in der Langzeittherapie der bipolaren Störung — was gibt es Neues?
verfasst von
Dr. med. univ. Johannes Petzold
Prof. Dr. med. Dr. rer. nat. Michael Bauer
PD Dr. med. habil. Emanuel Severus
Publikationsdatum
31.07.2017
Verlag
Springer Medizin
Erschienen in
DNP – Die Neurologie & Psychiatrie / Ausgabe 7-8/2017
Print ISSN: 2731-8168
Elektronische ISSN: 2731-8176
DOI
https://doi.org/10.1007/s15202-017-1742-3

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