Ausgabe 1/2012
Inhalt (172 Artikel)
Clinical application of stem cell therapy in Parkinson's disease
Marios Politis, Olle Lindvall
Frailty in primary care: a review of its conceptualization and implications for practice
Alethea Lacas, Kenneth Rockwood
suPAR as a prognostic biomarker in sepsis
Katia Donadello, Sabino Scolletta, Cecilia Covajes, Jean-Louis Vincent
The role of copeptin as a diagnostic and prognostic biomarker for risk stratification in the emergency department
Christian H Nickel, Roland Bingisser, Nils G Morgenthaler
Treatment of enterohemorrhagic Escherichia coli (EHEC) infection and hemolytic uremic syndrome (HUS)
Paul N Goldwater, Karl A Bettelheim
Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells
Yong Zhao, Zhaoshun Jiang, Tingbao Zhao, Mingliang Ye, Chengjin Hu, Zhaohui Yin, Heng Li, Ye Zhang, Yalin Diao, Yunxiang Li, Yingjian Chen, Xiaoming Sun, Mary Beth Fisk, Randal Skidgel, Mark Holterman, Bellur Prabhakar, Theodore Mazzone
Towards a genuinely medical model for psychiatric nosology
Randolph M Nesse, Dan J Stein
Spectrum of gluten-related disorders: consensus on new nomenclature and classification
Anna Sapone, Julio C Bai, Carolina Ciacci, Jernej Dolinsek, Peter HR Green, Marios Hadjivassiliou, Katri Kaukinen, Kamran Rostami, David S Sanders, Michael Schumann, Reiner Ullrich, Danilo Villalta, Umberto Volta, Carlo Catassi, Alessio Fasano
Clinical evaluation of iron treatment efficiency among non-anemic but iron-deficient female blood donors: a randomized controlled trial
Sophie Waldvogel, Baptiste Pedrazzini, Paul Vaucher, Raphael Bize, Jacques Cornuz, Jean-Daniel Tissot, Bernard Favrat
Zinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double blind placebo-controlled trial
Maheswari G Srinivasan, Grace Ndeezi, Cordelia Katureebe Mboijana, Sarah Kiguli, Gabriel S Bimenya, Victoria Nankabirwa, James K Tumwine
Location, location, location: the BRMS1 protein and melanoma progression
Adam I Riker, Rajeev S Samant
Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3)
Prabodh K Kandala, Sanjay K Srivastava
A public health approach to understanding and preventing violent radicalization
Kamaldeep S Bhui, Madelyn H Hicks, Myrna Lashley, Edgar Jones
Transcriptome changes in age-related macular degeneration
S Scott Whitmore, Robert F Mullins
Is the efficacy of psychopharmacological drugs comparable to the efficacy of general medicine medication?
Florian Seemüller, Hans-Jürgen Möller, Sandra Dittmann, Richard Musil
Is inhibition of kinase activity the only therapeutic strategy for LRRK2-associated Parkinson's disease?
Iakov N Rudenko, Ruth Chia, Mark R Cookson
Therapy for metastatic melanoma: the past, present, and future
Laura Finn, Svetomir N Markovic, Richard W Joseph
Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy
Melissa Bowerman, Lyndsay M Murray, Justin G Boyer, Carrie L Anderson, Rashmi Kothary
Advances in using PARP inhibitors to treat cancer
Shivaani Kummar, Alice Chen, Ralph E Parchment, Robert J Kinders, Jay Ji, Joseph E Tomaszewski, James H Doroshow
Viral hemorrhagic fevers: advancing the level of treatment
Giuseppe Ippolito, Heinz Feldmann, Simone Lanini, Francesco Vairo, Antonino Di Caro, Maria Rosaria Capobianchi, Emanuele Nicastri
Sufficient blood, safe blood: can we have both?
Halvard Bönig, Michael Schmidt, Kai Hourfar, Jörg Schüttrumpf, Erhard Seifried
Systematic review and meta-analysis of the value of initial biomarkers in predicting adverse outcome in febrile neutropenic episodes in children and young people with cancer
Robert S Phillips, Ros Wade, Thomas Lehrnbecher, Lesley A Stewart, Alex J Sutton
Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab
Gang Chen, Peter Kronenberger, Erik Teugels, Ijeoma Adaku Umelo, Jacques De Grève
Can racial disparities in optimal gout treatment be reduced? evidence from a randomized trial
Jasvinder A Singh
Crosstalk between HIV and hepatitis C virus during co-infection
Paul J Rider, Fenyong Liu
Rest versus exercise as treatment for patients with low back pain and Modic changes. a randomized controlled clinical trial
Rikke K Jensen, Charlotte Leboeuf-Yde, Niels Wedderkopp, Joan S Sorensen, Claus Manniche
Novel therapeutic strategies targeting HIV integrase
Peter K Quashie, Richard D Sloan, Mark A Wainberg
Differential susceptibility to plasticity: a 'missing link' between gene-culture co-evolution and neuropsychiatric spectrum disorders?
Rachel Wurzman, James Giordano
RETRACTED ARTICLE: Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function
Yingmei Zhang, Sara A Babcock, Nan Hu, Jacalyn R Maris, Haichang Wang, Jun Ren
Outbreaks of virulent diarrheagenic Escherichia coli- are we in control?
Dirk Werber, Gérard Krause, Christina Frank, Angelika Fruth, Antje Flieger, Martin Mielke, Lars Schaade, Klaus Stark
Apolipoprotein epsilon 3 alleles are associated with indicators of neuronal resilience
Orwa Aboud, Robert E Mrak, Frederick Boop, Sue T Griffin
Lifestyle factors affecting gastroesophageal reflux disease symptoms: a cross-sectional study of healthy 19864 adults using FSSG scores
Nobutake Yamamichi, Satoshi Mochizuki, Itsuko Asada-Hirayama, Rie Mikami-Matsuda, Takeshi Shimamoto, Maki Konno-Shimizu, Yu Takahashi, Chihiro Takeuchi, Keiko Niimi, Satoshi Ono, Shinya Kodashima, Chihiro Minatsuki, Mitsuhiro Fujishiro, Toru Mitsushima, Kazuhiko Koike
Insufficient maintenance DNA methylation is associated with abnormal embryonic development
Li-Jun Yin, Yu Zhang, Ping-Ping Lv, Wei-Hua He, Yan-Ting Wu, Ai-Xia Liu, Guo-Lian Ding, Min-Yue Dong, Fan Qu, Chen-Ming Xu, Xiao-Ming Zhu, He-Feng Huang
Viruses exacerbating chronic pulmonary disease: the role of immune modulation
Aran Singanayagam, Priya V Joshi, Patrick Mallia, Sebastian L Johnston
Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis
Atle Fretheim, Jan Odgaard-Jensen, Odd Brørs, Steinar Madsen, Inger Njølstad, Ole F Norheim, Arne Svilaas, Ivar S Kristiansen, Hanne Thürmer, Signe Flottorp
Evidence that an APOE ε4 'double whammy' increases risk for Alzheimer's disease
Ina Caesar, Sam Gandy
Lifestyle interventions for overweight and obese pregnant women to improve pregnancy outcome: systematic review and meta-analysis
Eugene Oteng-Ntim, Rajesh Varma, Helen Croker, Lucilla Poston, Pat Doyle
Novel regulatory therapies for prevention of Graft-versus-host disease
Joseph Leventhal, Yiming Huang, Hong Xu, Idona Goode, Suzanne T Ildstad
Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration
Douglas G Altman, Lisa M McShane, Willi Sauerbrei, Sheila E Taube
The effects of multi-domain versus single-domain cognitive training in non-demented older people: a randomized controlled trial
Yan Cheng, Wenyuan Wu, Wei Feng, Jiaqi Wang, You Chen, Yuan Shen, Qingwei Li, Xu Zhang, Chunbo Li
What is the evidence base to guide surgical treatment of infected hip prostheses? systematic review of longitudinal studies in unselected patients
Andrew D Beswick, Karen T Elvers, Alison J Smith, Rachael Gooberman-Hill, Andrew Lovering, Ashley W Blom
Stem cells and other innovative intra-articular therapies for osteoarthritis: what does the future hold?
Jasvinder A Singh
A new analysis approach of epidermal growth factor receptor pathway activation patterns provides insights into cetuximab resistance mechanisms in head and neck cancer
Silvia von der Heyde, Tim Beissbarth
Bioinformatic identification of proteins with tissue-specific expression for biomarker discovery
Ioannis Prassas, Caitlin C Chrystoja, Shalini Makawita, Eleftherios P Diamandis
The role of nutrition in integrated programs to control neglected tropical diseases
Andrew Hall, Yaobi Zhang, Chad MacArthur, Shawn Baker
New race and ethnicity standards: elucidating health disparities in diabetes
Peter T Katzmarzyk, Amanda E Staiano
Common variants in mismatch repair genes associated with increased risk of sperm DNA damage and male infertility
Guixiang Ji, Yan Long, Yong Zhou, Cong Huang, Aihua Gu, Xinru Wang
Statistical challenges in the development and evaluation of marker-based clinical tests
Lisa M McShane
Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: results from a randomized clinical trial
Khosrow S Houschyar, Rainer Lüdtke, Gustav J Dobos, Ulrich Kalus, Martina Broecker-Preuss, Thomas Rampp, Benno Brinkhaus, Andreas Michalsen
Therapeutic potential of transplanted placental mesenchymal stem cells in treating Chinese miniature pigs with acute liver failure
Hongcui Cao, Jinfeng Yang, Jiong Yu, Qiaoling Pan, Jianzhou Li, Pengcheng Zhou, Yanyuan Li, Xiaoping Pan, Jun Li, Yingjie Wang, Lanjuan Li
Potential immunological consequences of pharmacological suppression of gastric acid production in patients with multiple sclerosis
Sangita Biswas, Stephen H Benedict, Sharon G Lynch, Steven M LeVine
Coronary collaterals and risk for restenosis after percutaneous coronary interventions: a meta-analysis
Pascal Meier, Andreas Indermuehle, Bertram Pitt, Tobias Traupe, Stefano F de Marchi, Tom Crake, Guido Knapp, Alexandra J Lansky, Christian Seiler
Prevalence and prognosis of non-specific chest pain among patients hospitalized for suspected acute coronary syndrome - a systematic literature search
Vidar Ruddox, Mariann Mathisen, Jan Erik Otterstad
Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population
James K Ellis, Toby J Athersuch, Laura DK Thomas, Friederike Teichert, Miriam Pérez-Trujillo, Claus Svendsen, David J Spurgeon, Rajinder Singh, Lars Järup, Jacob G Bundy, Hector C Keun
A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls - a large case control study
Frank H Duffy, Heidelise Als
A systematic review of the effects of residency training on patient outcomes
Renée M van der Leeuw, Kiki MJMH Lombarts, Onyebuchi A Arah, Maas Jan Heineman
Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
Michael Maes, Michael Berk, Lisa Goehler, Cai Song, George Anderson, Piotr Gałecki, Brian Leonard
New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids
Michel de Lorgeril, Patricia Salen
Resitting a high-stakes postgraduate medical examination on multiple occasions: nonlinear multilevel modelling of performance in the MRCP(UK) examinations
IC McManus, Katarzyna Ludka
Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression
Emanuel Severus, Florian Seemüller, Michael Berger, Sandra Dittmann, Michael Obermeier, Andrea Pfennig, Michael Riedel, Sophia Frangou, Hans-Jürgen Möller, Michael Bauer
Month of birth, vitamin D and risk of immune-mediated disease: a case control study
Giulio Disanto, George Chaplin, Julia M Morahan, Gavin Giovannoni, Elina Hyppönen, George C Ebers, Sreeram V Ramagopalan
A commentary on TREAT: The trial of early aggressive drug therapy in juvenile idiopathic arthritis
Eileen Baildam
Open access versus subscription journals: a comparison of scientific impact
Bo-Christer Björk, David Solomon
Development and description of measurement properties of an instrument to assess treatment burden among patients with multiple chronic conditions
Viet-Thi Tran, Victor M Montori, David T Eton, Dan Baruch, Bruno Falissard, Philippe Ravaud
Commentary on a GWAS: HDAC9 and the risk for ischaemic stroke
Werner Hacke, Caspar Grond-Ginsbach
A cluster randomized trial to assess the effect of clinical pathways for patients with stroke: results of the clinical pathways for effective and appropriate care study
Massimiliano Panella, Sara Marchisio, Romeo Brambilla, Kris Vanhaecht, Francesco Di Stanislao
Sport and exercise medicine and the Olympic health legacy
Garry A Tew, Robert J Copeland, Simon H Till
Ultramarathon is an outstanding model for the study of adaptive responses to extreme load and stress
Grégoire P Millet, Guillaume Y Millet
Advances in sports nutrition, exercise and medicine: Olympic issues, the legacy and beyond
Mike Carmont
The effectiveness of neuromuscular warm-up strategies, that require no additional equipment, for preventing lower limb injuries during sports participation: a systematic review
Katherine Herman, Christian Barton, Peter Malliaras, Dylan Morrissey
Back to past leeches: repeated phlebotomies and cardiovascular risk
Melania Manco, Josè Manuel Fernandez-Real
The Transeurope Footrace Project: longitudinal data acquisition in a cluster randomized mobile MRI observational cohort study on 44 endurance runners at a 64-stage 4,486km transcontinental ultramarathon
Uwe HW Schütz, Arno Schmidt-Trucksäss, Beat Knechtle, Jürgen Machann, Heike Wiedelbach, Martin Ehrhardt, Wolfgang Freund, Stefan Gröninger, Horst Brunner, Ingo Schulze, Hans-Jürgen Brambs, Christian Billich
Antiviral activity of Bifidobacterium adolescentisSPM1005-A on human papillomavirus type 16
Min-Kyeong Cha, Do-Kyung Lee, Hyang-Mi An, Si-Won Lee, Seon-Hee Shin, Jeong-Hyun Kwon, Kyung-Jae Kim, Nam-Joo Ha
Born to run. Studying the limits of human performance
Andrew Murray, Ricardo JS Costa
Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models
Parul Gupta, Sanjay K Srivastava
Gender and the treatment of immune-mediated chronic inflammatory diseases: rheumatoid arthritis, inflammatory bowel disease and psoriasis: an observational study
Nienke Lesuis, Ragnar Befrits, Filippa Nyberg, Ronald F van Vollenhoven
The role of barrier membranes for guided bone regeneration and restoration of large bone defects: current experimental and clinical evidence
Rozalia Dimitriou, George I Mataliotakis, Giorgio Maria Calori, Peter V Giannoudis
Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker
Der-Yuan Chen, Huai-Chia Chuang, Joung-Liang Lan, Yi-Ming Chen, Wei-Ting Hung, Kuo-Lung Lai, Tse-Hua Tan
CD133+CXCR4+ colon cancer cells exhibit metastatic potential and predict poor prognosis of patients
Shan-shan Zhang, Zhi-peng Han, Ying-ying Jing, Shuang-fen Tao, Tie-jun Li, Hao Wang, Yang Wang, Rong Li, Yang Yang, Xue Zhao, Xiao-dong Xu, En-da Yu, Yao-cheng Rui, Hou-jia Liu, Li Zhang, Li-xin Wei
Physiologic variations of serum tumor markers in gynecological malignancies during pregnancy: a systematic review
Sileny N Han, Anouk Lotgerink, Mina Mhallem Gziri, Kristel Van Calsteren, Myriam Hanssens, Frédéric Amant
The failure of protein cancer biomarkers to reach the clinic: why, and what can be done to address the problem?
Eleftherios P Diamandis
State of progress in treating cystic fibrosis respiratory disease
Patrick A Flume, Donald R Van Devanter
A mathematical model to guide antibiotic treatment strategies
Albert Sotto, Jean-Philippe Lavigne
Tamoxifen for the management of breast events induced by non-steroidal antiandrogens in patients with prostate cancer: a systematic review
Frank Kunath, Bastian Keck, Gerd Antes, Bernd Wullich, Joerg J Meerpohl
Anatomy of open access publishing: a study of longitudinal development and internal structure
Mikael Laakso, Bo-Christer Björk
Implications of stress-induced genetic variation for minimizing multidrug resistance in bacteria
Uri Obolski, Lilach Hadany
Maintenance N-acetyl cysteine treatment for bipolar disorder: A double-blind randomized placebo controlled trial
Michael Berk, Olivia M Dean, Sue M Cotton, Clarissa S Gama, Flavio Kapczinski, Brisa Fernandes, Kristy Kohlmann, Susan Jeavons, Karen Hewitt, Kirsteen Moss, Christine Allwang, Ian Schapkaitz, Heidi Cobb, Ashley I Bush, Seetal Dodd, Gin S Malhi
Physiopathology of intratendinous calcific deposition
Francesco Oliva, Alessio Giai Via, Nicola Maffulli
Intracranial hemorrhage in adult patients with hematological malignancies
Chien-Yuan Chen, Chan-Hwei Tai, Aristine Cheng, Hung-Chang Wu, Woei Tsay, Jia-Hau Liu, Pey-Ying Chen, Shang-Yi Huang, Ming Yao, Jih-Luh Tang, Hwei-Fang Tien
Toll-like receptor 4 signaling promotes epithelial-mesenchymal transition in human hepatocellular carcinoma induced by lipopolysaccharide
Ying-Ying Jing, Zhi-Peng Han, Kai Sun, Shan-Shan Zhang, Jing Hou, Yan Liu, Rong Li, Lu Gao, Xue Zhao, Qiu-Dong Zhao, Meng-Chao Wu, Li-Xin Wei
Effect of a multifactorial interdisciplinary intervention on mobility-related disability in frail older people: randomised controlled trial
Nicola Fairhall, Catherine Sherrington, Susan E Kurrle, Stephen R Lord, Keri Lockwood, Ian D Cameron
Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study
Bernd Kronenberger, Ina Rudloff, Malte Bachmann, Friederike Brunner, Lisa Kapper, Natalie Filmann, Oliver Waidmann, Eva Herrmann, Josef Pfeilschifter, Stefan Zeuzem, Albrecht Piiper, Heiko Mühl
Human amniotic fluid stem cell injection therapy for urethral sphincter regeneration in an animal model
Bum Soo Kim, So Young Chun, Jong Kil Lee, Hyun Ju Lim, Jae-sung Bae, Ho-Yun Chung, Anthony Atala, Shay Soker, James J Yoo, Tae Gyun Kwon
A systematic review and analysis of long-term outcomes in attention deficit hyperactivity disorder: effects of treatment and non-treatment
Monica Shaw, Paul Hodgkins, Hervé Caci, Susan Young, Jennifer Kahle, Alisa G Woods, L Eugene Arnold
ICU-acquired weakness: what is preventing its rehabilitation in critically ill patients?
Christie M Lee, Eddy Fan
Estimation of outbreak severity and transmissibility: Influenza A(H1N1)pdm09 in households
Thomas House, Nadia Inglis, Joshua V Ross, Fay Wilson, Shakeel Suleman, Obaghe Edeghere, Gillian Smith, Babatunde Olowokure, Matt J Keeling
Toward unbiased assessment of treatment and prevention: modeling household transmission of pandemic influenza
Gerardo Chowell, Hiroshi Nishiura
Dietary iron intake, body iron stores, and the risk of type 2 diabetes: a systematic review and meta-analysis
Wei Bao, Ying Rong, Shuang Rong, Liegang Liu
Using lithium as a neuroprotective agent in patients with cancer
Mustafa Khasraw, David Ashley, Greg Wheeler, Michael Berk
Commentary on a recent review of lithium toxicity: what are its implications for clinical practice?
Bruno Müller-Oerlinghausen, Michael Bauer, Paul Grof
Is belief larger than fact: expectations, optimism and reality for translational stem cell research
Tania Bubela, Matthew D Li, Mohamed Hafez, Mark Bieber, Harold Atkins
Cardiac-specific catalase overexpression rescues anthrax lethal toxin-induced cardiac contractile dysfunction: role of oxidative stress and autophagy
Machender R Kandadi, Xuejun Yu, Arthur E Frankel, Jun Ren
Prognostic value of KRAS genotype in metastatic colorectal cancer (MCRC) patients treated with intensive triplet chemotherapy plus bevacizumab (FIr-B/FOx) according to extension of metastatic disease
Gemma Bruera, Katia Cannita, Daniela Di Giacomo, Aude Lamy, Giancarlo Troncone, Antonella Dal Mas, Gino Coletti, Thierry Frébourg, Jean Christophe Sabourin, Mario Tosi, Corrado Ficorella, Enrico Ricevuto
A case study using the United Republic of Tanzania: costing nationwide HPV vaccine delivery using the WHO Cervical Cancer Prevention and Control Costing Tool
Raymond Hutubessy, Ann Levin, Susan Wang, Winthrop Morgan, Mariam Ally, Theopista John, Nathalie Broutet
Costs of delivering human papillomavirus vaccination to schoolgirls in Mwanza Region, Tanzania
Wilm Quentin, Fern Terris-Prestholt, John Changalucha, Selephina Soteli, W John Edmunds, Raymond Hutubessy, David A Ross, Saidi Kapiga, Richard Hayes, Deborah Watson-Jones
Commentary on the clinical management of metabolic syndrome: why a healthy lifestyle is important
Michel de Lorgeril
Mammalian NPC1 genes may undergo positive selection and human polymorphisms associate with type 2 diabetes
Nasser M Al-Daghri, Rachele Cagliani, Diego Forni, Majed S Alokail, Uberto Pozzoli, Khalid M Alkharfy, Shaun Sabico, Mario Clerici, Manuela Sironi
Notch signaling in pediatric soft tissue sarcomas
Rossella Rota, Roberta Ciarapica, Lucio Miele, Franco Locatelli
Impact of evergreening on patients and health insurance: a meta analysis and reimbursement cost analysis of citalopram/escitalopram antidepressants
Ali A Alkhafaji, Ludovic Trinquart, Gabriel Baron, Moïse Desvarieux, Philippe Ravaud
Methodological quality of English-language genetic guidelines on hereditary breast-cancer screening and management: an evaluation using the AGREE instrument
Benedetto Simone, Emma De Feo, Nicola Nicolotti, Walter Ricciardi, Stefania Boccia
Renal cancer biomarkers: the promise of personalized care
Naveen S Vasudev, Peter J Selby, Rosamonde E Banks
Integrating pathology and radiology disciplines: an emerging opportunity?
James Sorace, Denise R Aberle, Dena Elimam, Silvana Lawvere, Ossama Tawfik, W Dean Wallace
Transforming growth factor β1 inhibits bone morphogenic protein (BMP)-2 and BMP-7 signaling via upregulation of Ski-related novel protein N (SnoN): possible mechanism for the failure of BMP therapy?
Sabrina Ehnert, Jian Zhao, Stefan Pscherer, Thomas Freude, Steven Dooley, Andreas Kolk, Ulrich Stöckle, Andreas Klaus Nussler, Robert Hube
A tool to facilitate clinical biomarker studies - a tissue dictionary based on the Human Protein Atlas
Caroline Kampf, Julia Bergman, Per Oksvold, Anna Asplund, Sanjay Navani, Mikaela Wiking, Emma Lundberg, Mathias Uhlén, Fredrik Ponten
Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis
Rui Liu, Cai-xia Wu, Dan Zhou, Fan Yang, Shuo Tian, Li Zhang, Tian-tai Zhang, Guan-hua Du
Epilepsy care guidelines for low- and middle- income countries: From WHO mental health GAP to national programs
Juri Katchanov, Gretchen L Birbeck
Obesity and prostate cancer: gene expression signature of human periprostatic adipose tissue
Ricardo Ribeiro, Cátia Monteiro, Victoria Catalán, Pingzhao Hu, Virgínia Cunha, Amaia Rodríguez, Javier Gómez-Ambrosi, Avelino Fraga, Paulo Príncipe, Carlos Lobato, Francisco Lobo, António Morais, Vitor Silva, José Sanches-Magalhães, Jorge Oliveira, Francisco Pina, Carlos Lopes, Rui Medeiros, Gema Frühbeck
The relationship between obesity and prostate cancer: from genetics to disease treatment and prevention
Giovanni Lughezzani
Individual differences and evidence-based psychopharmacology
RH Belmaker, Yuly Bersudsky, Galila Agam
Is diagnosis enough to guide interventions in mental health? Using case formulation in clinical practice
Craig A Macneil, Melissa K Hasty, Philippe Conus, Michael Berk
Making mobility-related disability better: a complex response to a complex problem
Kenneth Rockwood
Autophagy in periodontitis patients and gingival fibroblasts: unraveling the link between chronic diseases and inflammation
Pedro Bullon, Mario David Cordero, José Luis Quiles, Maria del Carmen Ramirez-Tortosa, Adrian Gonzalez-Alonso, Simona Alfonsi, Rocio García-Marín, Manuel de Miguel, Maurizio Battino
Cigarette smoking, nicotine dependence and anxiety disorders: a systematic review of population-based, epidemiological studies
Steven Moylan, Felice N Jacka, Julie A Pasco, Michael Berk
Correlation analyses of clinical and molecular findings identify candidate biological pathways in systemic juvenile idiopathic arthritis
Xuefeng B Ling, Claudia Macaubas, Heather C Alexander, Qiaojun Wen, Edward Chen, Sihua Peng, Yue Sun, Chetan Deshpande, Kuang-Hung Pan, Richard Lin, Chih-Jian Lih, Sheng-Yung P Chang, Tzielan Lee, Christy Sandborg, Ann B Begovich, Stanley N Cohen, Elizabeth D Mellins
Health surveillance of deployed military personnel occasionally leads to unexpected findings
Alexander C McFarlane
Preclinical Alzheimer disease: identification of cases at risk among cognitively intact older individuals
Maciej J Lazarczyk, Patrick R Hof, Constantin Bouras, Panteleimon Giannakopoulos
Prevalence and incidence density rates of chronic comorbidity in type 2 diabetes patients: an exploratory cohort study
Hilde Luijks, Tjard Schermer, Hans Bor, Chris van Weel, Toine Lagro-Janssen, Marion Biermans, Wim de Grauw
Effects of lifestyle modification on metabolic syndrome: a systematic review and meta-analysis
Kazue Yamaoka, Toshiro Tango
Apps for asthma self-management: a systematic assessment of content and tools
Kit Huckvale, Mate Car, Cecily Morrison, Josip Car
Mortality and guideline-concordant care for older patients with schizophrenia: a retrospective longitudinal study
Jack Y Tsan, Eileen M Stock, Jazmin M Gonzalez, David S Greenawalt, John E Zeber, Emran Rouf, Laurel A Copeland
Increased risk of affective disorders in type 2 diabetes is minimized by sulfonylurea and metformin combination: a population-based cohort study
Mark L Wahlqvist, Meei-Shyuan Lee, Shao-Yuan Chuang, Chih-Cheng Hsu, Hsin-Ni Tsai, Shu-Han Yu, Hsing-Yi Chang
How evidence-based is an 'evidence-based parenting program'? A PRISMA systematic review and meta-analysis of Triple P
Philip Wilson, Robert Rush, Susan Hussey, Christine Puckering, Fiona Sim, Clare S Allely, Paul Doku, Alex McConnachie, Christopher Gillberg
A commentary on evidenced-based parenting programs: redressing misconceptions of the empirical support for Triple P
Matthew R Sanders, John A Pickering, James N Kirby, Karen MT Turner, Alina Morawska, Trevor Mazzucchelli, Alan Ralph, Kate Sofronoff
The physician's unique role in preventing violence: a neglected opportunity?
John C Umhau, Karysse Trandem, Mohsin Shah, David T George
Modeling rapidly disseminating infectious disease during mass gatherings
Gerardo Chowell, Hiroshi Nishiura, Cécile Viboud
Co-prescription of medication for bipolar disorder and diabetes mellitus: a nationwide population-based study with focus on gender differences
Gjertrud Svendal, Ole Bernt Fasmer, Anders Engeland, Michael Berk, Anders Lund
Moving towards a population health approach to the primary prevention of common mental disorders
Felice N Jacka, Arnstein Mykletun, Michael Berk
Clinical development of phosphatidylinositol 3-kinase inhibitors for cancer treatment
Irene Brana, Lillian L Siu
The age distribution of mortality due to influenza: pandemic and peri-pandemic
Tom Reichert, Gerardo Chowell, Jonathan A McCullers
Breast cancer screening: evidence of benefit depends on the method used
Philippe Autier, Mathieu Boniol
Cycling and bone health: a systematic review
Hugo Olmedillas, Alejandro González-Agüero, Luis A Moreno, José A Casajus, Germán Vicente-Rodríguez
Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences
Witold Czyz, Julia M Morahan, George C Ebers, Sreeram V Ramagopalan
Data-driven subtypes of major depressive disorder: a systematic review
Hanna M van Loo, Peter de Jonge, Jan-Willem Romeijn, Ronald C Kessler, Robert A Schoevers
Serum protein profiles predict coronary artery disease in symptomatic patients referred for coronary angiography
William A LaFramboise, Rajiv Dhir, Lori A Kelly, Patricia Petrosko, John M Krill-Burger, Christin M Sciulli, Maureen A Lyons-Weiler, Uma R Chandran, Aleksey Lomakin, Robert V Masterson, Oscar C Marroquin, Suresh R Mulukutla, Dennis M McNamara
Validation of a model to investigate the effects of modifying cardiovascular disease (CVD) risk factors on the burden of CVD: the rotterdam ischemic heart disease and stroke computer simulation (RISC) model
Bob JH van Kempen, Bart S Ferket, Albert Hofman, Ewout W Steyerberg, Ersen B Colkesen, S Matthijs Boekholdt, Nicholas J Wareham, Kay-Tee Khaw, MG Myriam Hunink
Substantial and reversible brain gray matter reduction but no acute brain lesions in ultramarathon runners: experience from the TransEurope-FootRace Project
Wolfgang Freund, Sonja Faust, Frank Birklein, Christian Gaser, Arthur P Wunderlich, Marguerite Müller, Christian Billich, Markus S Juchems, Bernd L Schmitz, Georg Grön, Uwe H Schütz
Evidence from neuroimaging to explore brain plasticity in humans during an ultra-endurance burden
Stéphane Perrey, Kevin Mandrick
The impact of statins on psychological wellbeing: a systematic review and meta-analysis
Adrienne O'Neil, Livia Sanna, Cassie Redlich, Kristy Sanderson, Felice Jacka, Lana J Williams, Julie A Pasco, Michael Berk
Passive smoking, invasive meningococcal disease and preventive measures: a commentary
Harunor Rashid, Robert Booy
Bike racing, recreational riding, impact sport and bone health
Michael R Carmont
Perinatal nicotine exposure induces asthma in second generation offspring
Virender K Rehan, Jie Liu, Erum Naeem, Jia Tian, Reiko Sakurai, Kenny Kwong, Omid Akbari, John S Torday
Personalized medicine and atrial fibrillation: will it ever happen?
Steven A Lubitz, Patrick T Ellinor
Pre-cooling for endurance exercise performance in the heat: a systematic review
Paul R Jones, Christian Barton, Dylan Morrissey, Nicola Maffulli, Stephanie Hemmings
Exercise therapy for bone and muscle health: an overview of systematic reviews
Kåre Birger Hagen, Hanne Dagfinrud, Rikke Helene Moe, Nina Østerås, Ingvild Kjeken, Margreth Grotle, Geir Smedslund
Immunotherapy using slow-cycling tumor cells prolonged overall survival of tumor-bearing mice
Qing Sun, Yong Zhong, Fan Wu, Chunxia Zhou, Dongmei Wang, Wenbo Ma, Youhui Zhang, Shuren Zhang
Glucagon-like peptide-1 analogs against antipsychotic-induced weight gain: potential physiological benefits
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