Ausgabe 1/2015
Inhalt (150 Artikel)
The use of the Gail model, body mass index and SNPs to predict breast cancer among women with abnormal (BI-RADS 4) mammograms
Anne Marie McCarthy, Brad Keller, Despina Kontos, Leigh Boghossian, Erin McGuire, Mirar Bristol, Jinbo Chen, Susan Domchek, Katrina Armstrong
Circulating tumor cells in newly diagnosed inflammatory breast cancer
Michal Mego, Antonio Giordano, Ugo De Giorgi, Hiroko Masuda, Limin Hsu, Mario Giuliano, Tamer M Fouad, Shaheenah Dawood, Naoto T Ueno, Vicente Valero, Eleni Andreopoulou, Ricardo H Alvarez, Wendy A Woodward, Gabriel N Hortobagyi, Massimo Cristofanilli, James M Reuben
Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis
Mario Giuliano, Sabrina Herrera, Pavel Christiny, Chad Shaw, Chad J Creighton, Tamika Mitchell, Raksha Bhat, Xiaomei Zhang, Sufeng Mao, Lacey E Dobrolecki, Ahmed Al-rawi, Fengju Chen, Bianca M Veneziani, Xiang H-F Zhang, Susan G Hilsenbeck, Alejandro Contreras, Carolina Gutierrez, Rinath M Jeselsohn, Mothaffar F Rimawi, C Kent Osborne, Michael T Lewis, Rachel Schiff, Meghana V Trivedi
A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation
Angela Burleigh, Steven McKinney, Jazmine Brimhall, Damian Yap, Peter Eirew, Steven Poon, Viola Ng, Adrian Wan, Leah Prentice, Lois Annab, J Carl Barrett, Carlos Caldas, Connie Eaves, Samuel Aparicio
BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers
Zannel Blanchard, Bibbin T Paul, Barbara Craft, Wael M ElShamy
Targeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell death
Hye Joung Choi, Asona Lui, Joshua Ogony, Rifat Jan, Peter J Sims, Joan Lewis-Wambi
Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity
Roshan Sriram, Vivian Lo, Benjamin Pryce, Lilia Antonova, Alan J Mears, Manijeh Daneshmand, Bruce McKay, Simon J Conway, William J Muller, Luc A Sabourin
Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer
Reuben S Harris
Erratum to: “A novel role for ezrin in breast cancer angio/lymphangiogenesis”
Abdi Ghaffari, Victoria Hoskin, Alvin Szeto, Maaike Hum, Navid Liaghati, Kanji Nakatsu, David LeBrun, Yolanda Madarnas, Sandip SenGupta, Bruce E Elliott
Markers for the identification of late breast cancer recurrence
Ivana Sestak, Jack Cuzick
Multigene prognostic tests in breast cancer: past, present, future
Balázs Győrffy, Christos Hatzis, Tara Sanft, Erin Hofstatter, Bilge Aktas, Lajos Pusztai
Invasive lobular carcinoma of the breast: morphology, biomarkers and ’omics
Amy E McCart Reed, Jamie R Kutasovic, Sunil R Lakhani, Peter T Simpson
MicroRNA-125b upregulation confers aromatase inhibitor resistance and is a novel marker of poor prognosis in breast cancer
Paul Vilquin, Caterina F Donini, Marie Villedieu, Evelyne Grisard, Laura Corbo, Thomas Bachelot, Julie A Vendrell, Pascale A Cohen
Mammary gland tumor promotion by chronic administration of IGF1 and the insulin analogue AspB10 in the p53R270H/+WAPCre mouse model
Bas ter Braak, Christine Siezen, Ewoud N Speksnijder, Esmee Koedoot, Harry van Steeg, Daniela CF Salvatori, Bob van de Water, Jan Willem van der Laan
Coffee and tea consumption and risk of pre- and postmenopausal breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study
Nirmala Bhoo-Pathy, Petra HM Peeters, Cuno SPM Uiterwaal, H Bas Bueno-de-Mesquita, Awang M Bulgiba, Bodil Hammer Bech, Kim Overvad, Anne Tjønneland, Anja Olsen, Françoise Clavel-Chapelon, Guy Fagherazzi, Florence Perquier, Birgit Teucher, Rudolf Kaaks, Madlen Schütze, Heiner Boeing, Pagona Lagiou, Philippos Orfanos, Antonia Trichopoulou, Claudia Agnoli, Amalia Mattiello, Domenico Palli, Rosario Tumino, Carlotta Sacerdote, Franzel JB van Duijnhoven, Tonje Braaten, Eiliv Lund, Guri Skeie, María-Luisa Redondo, Genevieve Buckland, Maria José Sánchez Pérez, Maria-Dolores Chirlaque, Eva Ardanaz, Pilar Amiano, Elisabet Wirfält, Peter Wallström, Ingegerd Johansson, Lena Maria Nilsson, Kay-Tee Khaw, Nick Wareham, Naomi E Allen, Timothy J Key, Sabina Rinaldi, Isabelle Romieu, Valentina Gallo, Elio Riboli, Carla H van Gils
Lobular breast cancer: molecular basis, mouse and cellular models
Matthias Christgen, Patrick WB Derksen
Patient-derived xenograft models of breast cancer and their predictive power
James R Whittle, Michael T Lewis, Geoffrey J Lindeman, Jane E Visvader
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy
Jieping Lei, Anja Rudolph, Kirsten B Moysich, Sajjad Rafiq, Sabine Behrens, Ellen L Goode, Paul PD Pharoah, Petra Seibold, Peter A Fasching, Irene L Andrulis, Vessela N Kristensen, Fergus J Couch, Ute Hamann, Maartje J Hooning, Heli Nevanlinna, Ursula Eilber, Manjeet K Bolla, Joe Dennis, Qin Wang, Annika Lindblom, Arto Mannermaa, Diether Lambrechts, Montserrat García-Closas, Per Hall, Georgia Chenevix-Trench, Mitul Shah, Robert Luben, Lothar Haeberle, Arif B Ekici, Matthias W Beckmann, Julia A Knight, Gord Glendon, Sandrine Tchatchou, Grethe I Grenaker Alnæs, Anne-Lise Borresen-Dale, Silje Nord, Janet E Olson, Emily Hallberg, Celine Vachon, Diana Torres, Hans-Ulrich Ulmer, Thomas Rüdiger, Agnes Jager, Carolien HM van Deurzen, Madeleine MA Tilanus-Linthorst, Taru A Muranen, Kristiina Aittomäki, Carl Blomqvist, Sara Margolin, Veli-Matti Kosma, Jaana M Hartikainen, Vesa Kataja, Sigrid Hatse, Hans Wildiers, Ann Smeets, Jonine Figueroa, Stephen J Chanock, Jolanta Lissowska, Jingmei Li, Keith Humphreys, Kelly-Anne Phillips, Sabine Linn, Sten Cornelissen, Sandra Alexandra J van den Broek, Daehee Kang, Ji-Yeob Choi, Sue K Park, Keun-Young Yoo, Chia-Ni Hsiung, Pei-Ei Wu, Ming-Feng Hou, Chen-Yang Shen, Soo Hwang Teo, Nur Aishah Mohd Taib, Cheng Har Yip, Gwo Fuang Ho, Keitaro Matsuo, Hidemi Ito, Hiroji Iwata, Kazuo Tajima, Alison M Dunning, Javier Benitez, Kamila Czene, Lara E Sucheston, Tom Maishman, William J Tapper, Diana Eccles, Douglas F Easton, Marjanka K Schmidt, Jenny Chang-Claude
Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy
Betsy T Kren, Gretchen M Unger, Md J Abedin, Rachel I Vogel, Christine M Henzler, Khalil Ahmed, Janeen H Trembley
Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth
Xiu-Rong Ren, Jiangbo Wang, Takuya Osada, Robert A Mook Jr, Michael A Morse, Larry S Barak, Herbert Kim Lyerly, Wei Chen
Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management
Eleni van Schooneveld, Hans Wildiers, Ignace Vergote, Peter B Vermeulen, Luc Y Dirix, Steven J Van Laere
A case–control analysis of oral contraceptive use and breast cancer subtypes in the African American Breast Cancer Epidemiology and Risk Consortium
Traci N Bethea, Lynn Rosenberg, Chi-Chen Hong, Melissa A Troester, Kathryn L Lunetta, Elisa V Bandera, Pepper Schedin, Laurence N Kolonel, Andrew F Olshan, Christine B Ambrosone, Julie R Palmer
Prognostic stromal gene signatures in breast cancer
Sofia Winslow, Karin Leandersson, Anders Edsjö, Christer Larsson
RANK-ligand (RANKL) expression in young breast cancer patients and during pregnancy
Hatem A Azim Jr, Fedro A Peccatori, Sylvain Brohée, Daniel Branstetter, Sherene Loi, Giuseppe Viale, Martine Piccart, William C Dougall, Giancarlo Pruneri, Christos Sotiriou
Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer
Sergio Granados-Principal, Yi Liu, Maria L Guevara, Elvin Blanco, Dong Soon Choi, Wei Qian, Tejal Patel, Angel A Rodriguez, Joseph Cusimano, Heidi L Weiss, Hong Zhao, Melissa D Landis, Bhuvanesh Dave, Steven S Gross, Jenny C Chang
Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpression
Paromita Raha, Scott Thomas, K Ted Thurn, Jeenah Park, Pamela N Munster
In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α
Kriti Singh, Ravi Shashi Nayana Munuganti, Eric Leblanc, Yu Lun Lin, Euphemia Leung, Nada Lallous, Miriam Butler, Artem Cherkasov, Paul S Rennie
Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models
Yihao Li, Yvette Drabsch, Philippe Pujuguet, Jiang Ren, Theo van Laar, Long Zhang, Hans van Dam, Philippe Clément-Lacroix, Peter ten Dijke
Molecular subtyping for clinically defined breast cancer subgroups
Xi Zhao, Einar Andreas Rødland, Robert Tibshirani, Sylvia Plevritis
FOXF2 deficiency promotes epithelial-mesenchymal transition and metastasis of basal-like breast cancer
Qing-Shan Wang, Peng-Zhou Kong, Xiao-Qing Li, Fan Yang, Yu-Mei Feng
Mouse mammary stem cells express prognostic markers for triple-negative breast cancer
Kelly J Soady, Howard Kendrick, Qiong Gao, Andrew Tutt, Marketa Zvelebil, Liliana D Ordonez, Jelmar Quist, David Wei-Min Tan, Clare M Isacke, Anita Grigoriadis, Matthew J Smalley
Changes in insulin receptor signaling underlie neoadjuvant metformin administration in breast cancer: a prospective window of opportunity neoadjuvant study
Ryan JO Dowling, Saroj Niraula, Martin C Chang, Susan J Done, Marguerite Ennis, David R McCready, Wey L Leong, Jaime M Escallon, Michael Reedijk, Pamela J Goodwin, Vuk Stambolic
Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells
Ahrum Min, Seock-Ah Im, Debora Keunyoung Kim, Sang-Hyun Song, Hee-Jun Kim, Kyung-Hun Lee, Tae-Yong Kim, Sae-Won Han, Do-Youn Oh, Tae-You Kim, Mark J O’Connor, Yung-Jue Bang
Presence of circulating Her2-reactive CD8 + T-cells is associated with lower frequencies of myeloid-derived suppressor cells and regulatory T cells, and better survival in older breast cancer patients
Jithendra Kini Bailur, Brigitte Gueckel, Evelyna Derhovanessian, Graham Pawelec
Integrative analyses identify modulators of response to neoadjuvant aromatase inhibitors in patients with early breast cancer
Elena López-Knowles, Paul M Wilkerson, Ricardo Ribas, Helen Anderson, Alan Mackay, Zara Ghazoui, Aradhana Rani, Peter Osin, Ash Nerurkar, Lorna Renshaw, Alexey Larionov, William R Miller, J Michael Dixon, Jorge S Reis-Filho, Anita K Dunbier, Lesley-Ann Martin, Mitch Dowsett
Lectin RCA-I specifically binds to metastasis-associated cell surface glycans in triple-negative breast cancer
Shu-Min Zhou, Li Cheng, Shu-Juan Guo, Yang Wang, Daniel M Czajkowsky, Huafang Gao, Xiao-Fang Hu, Sheng-Ce Tao
Lobular breast cancer: incidence and genetic and non-genetic risk factors
Laure Dossus, Patrick R Benusiglio
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Julie Decock, Wouter Hendrickx, Sally Thirkettle, Ana Gutiérrez-Fernández, Stephen D Robinson, Dylan R Edwards
Estimated dietary dioxin exposure and breast cancer risk among women from the French E3N prospective cohort
Aurélie MN Danjou, Béatrice Fervers, Marie-Christine Boutron-Ruault, Thierry Philip, Françoise Clavel-Chapelon, Laure Dossus
Mechanisms of endocrine resistance in breast cancer: an overview of the proposed roles of noncoding RNA
Erin L Hayes, Joan S Lewis-Wambi
Quantitative measurement of HER2 expression in breast cancers: comparison with ‘real-world’ routine HER2 testing in a multicenter Collaborative Biomarker Study and correlation with overall survival
Denise A Yardley, Peter A Kaufman, Weidong Huang, Lea Krekow, Michael Savin, William E Lawler, Stephen Zrada, Alexander Starr, Harvey Einhorn, Lee S Schwartzberg, John W Adams, Yolanda Lie, Agnes C Paquet, Jeff Sperinde, Mojgan Haddad, Steve Anderson, Marlon Brigino, Rick Pesano, Michael P Bates, Jodi Weidler, Linda Bosserman
Mesenchymal stem cells mediate the clinical phenotype of inflammatory breast cancer in a preclinical model
Lara Lacerda, Bisrat G Debeb, Daniel Smith, Richard Larson, Travis Solley, Wei Xu, Savitri Krishnamurthy, Yun Gong, Lawrence B Levy, Thomas Buchholz, Naoto T Ueno, Ann Klopp, Wendy A Woodward
Gene-expression molecular subtyping of triple-negative breast cancer tumours: importance of immune response
Pascal Jézéquel, Delphine Loussouarn, Catherine Guérin-Charbonnel, Loïc Campion, Antoine Vanier, Wilfried Gouraud, Hamza Lasla, Catherine Guette, Isabelle Valo, Véronique Verrièle, Mario Campone
Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF
Mari Tinholt, Hans Kristian Moen Vollan, Kristine Kleivi Sahlberg, Sandra Jernström, Fatemeh Kaveh, Ole Christian Lingjærde, Rolf Kåresen, Torill Sauer, Vessela Kristensen, Anne-Lise Børresen-Dale, Per Morten Sandset, Nina Iversen
Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases
Sébastien Tabariès, Véronique Ouellet, Brian E Hsu, Matthew G Annis, April AN Rose, Liliane Meunier, Euridice Carmona, Christine E Tam, Anne-Marie Mes-Masson, Peter M Siegel
Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy
Kimberly A Snyder, Michael R Hughes, Bradley Hedberg, Jill Brandon, Diana Canals Hernaez, Peter Bergqvist, Frederic Cruz, Kelvin Po, Marcia L Graves, Michelle E Turvey, Julie S Nielsen, John A Wilkins, Shaun R McColl, John S Babcook, Calvin D Roskelley, Kelly M McNagny
FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth
Isabelle Tancioni, Nichol LG Miller, Sean Uryu, Christine Lawson, Christine Jean, Xiao Lei Chen, Elizabeth G Kleinschmidt, David D Schlaepfer
Enhanced anti-tumor immune responses and delay of tumor development in human epidermal growth factor receptor 2 mice immunized with an immunostimulatory peptide in poly(D,L-lactic-co-glycolic) acid nanoparticles
Diahnn F Campbell, Rebecca Saenz, Ila S Bharati, Daniel Seible, Liangfang Zhang, Sadik Esener, Bradley Messmer, Marie Larsson, Davorka Messmer
Circulating prolactin and in situ breast cancer risk in the European EPIC cohort: a case-control study
Kaja Tikk, Disorn Sookthai, Renée T Fortner, Theron Johnson, Sabina Rinaldi, Isabelle Romieu, Anne Tjønneland, Anja Olsen, Kim Overvad, Françoise Clavel-Chapelon, Laura Baglietto, Heiner Boeing, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Giovanna Masala, Vittorio Krogh, Rosario Tumino, Fulvio Ricceri, Amalia Mattiello, Antonio Agudo, Virginia Menéndez, María-José Sánchez, Pilar Amiano, Maria-Dolores Chirlaque, Aurelio Barricarte, HBas Bueno-de-Mesquita, Evelyn M Monninkhof, N Charlotte Onland-Moret, Anne Andresson, Malin Sund, Elisabete Weiderpass, Kay-Tee Khaw, Timothy J Key, Ruth C Travis, Melissa A Merritt, Elio Riboli, Laure Dossus, Rudolf Kaaks
Background risk of breast cancer and the association between physical activity and mammographic density
Thang Trinh, Mikael Eriksson, Hatef Darabi, Stephanie E Bonn, Judith S Brand, Jack Cuzick, Kamila Czene, Arvid Sjölander, Katarina Bälter, Per Hall
Targeting PTEN-defined breast cancers with a one-two punch
Leonard B Maggi Jr, Jason D Weber
The clinical and functional significance of c-Met in breast cancer: a review
Colan M Ho-Yen, J Louise Jones, Stephanie Kermorgant
Quantification of HER family receptors in breast cancer
Paolo Nuciforo, Nina Radosevic-Robin, Tony Ng, Maurizio Scaltriti
The E2F4 prognostic signature is also predictive of the pathological response of breast cancer to chemotherapy
François Bertucci, Pascal Finetti, Daniel Birnbaum
Long non-coding RNA expression profiles predict metastasis in lymph node-negative breast cancer independently of traditional prognostic markers
Kristina P Sørensen, Mads Thomassen, Qihua Tan, Martin Bak, Søren Cold, Mark Burton, Martin J Larsen, Torben A Kruse
Long-term hazard of recurrence in HER2+ breast cancer patients untreated with anti-HER2 therapy
Kathrin Strasser-Weippl, Nora Horick, Ian E Smith, Joyce O’Shaughnessy, Bent Ejlertsen, Frances Boyle, Aman U Buzdar, Pierre Fumoleau, William Gradishar, Miguel Martin, Beverly Moy, Martine Piccart-Gebhart, Kathleen I Pritchard, Deborah Lindquist, Erica Rappold, Dianne M Finkelstein, Paul E Goss
Adipose cells promote resistance of breast cancer cells to trastuzumab-mediated antibody-dependent cellular cytotoxicity
Minh Ngoc Duong, Aurore Cleret, Eva-Laure Matera, Kamel Chettab, Doriane Mathé, Sandrine Valsesia-Wittmann, Béatrice Clémenceau, Charles Dumontet
Common germline polymorphisms associated with breast cancer-specific survival
Ailith Pirie, Qi Guo, Peter Kraft, Sander Canisius, Diana M Eccles, Nazneen Rahman, Heli Nevanlinna, Constance Chen, Sofia Khan, Jonathan Tyrer, Manjeet K Bolla, Qin Wang, Joe Dennis, Kyriaki Michailidou, Michael Lush, Alison M Dunning, Mitul Shah, Kamila Czene, Hatef Darabi, Mikael Eriksson, Dieter Lambrechts, Caroline Weltens, Karin Leunen, Chantal van Ongeval, Børge G Nordestgaard, Sune F Nielsen, Henrik Flyger, Anja Rudolph, Petra Seibold, Dieter Flesch-Janys, Carl Blomqvist, Kristiina Aittomäki, Rainer Fagerholm, Taru A Muranen, Janet E Olsen, Emily Hallberg, Celine Vachon, Julia A Knight, Gord Glendon, Anna Marie Mulligan, Annegien Broeks, Sten Cornelissen, Christopher A Haiman, Brian E Henderson, Frederick Schumacher, Loic Le Marchand, John L Hopper, Helen Tsimiklis, Carmel Apicella, Melissa C Southey, Simon S Cross, Malcolm WR Reed, Graham G Giles, Roger L Milne, Catriona McLean, Robert Winqvist, Katri Pylkäs, Arja Jukkola-Vuorinen, Mervi Grip, Maartje J Hooning, Antoinette Hollestelle, John WM Martens, Ans MW van den Ouweland, Federick Marme, Andreas Schneeweiss, Rongxi Yang, Barbara Burwinkel, Jonine Figueroa, Stephen J Chanock, Jolanta Lissowska, Elinor J Sawyer, Ian Tomlinson, Michael J Kerin, Nicola Miller, Hermann Brenner, Katja Butterbach, Bernd Holleczek, Vesa Kataja, Veli-Matti Kosma, Jaana M Hartikainen, Jingmei Li, Judith S Brand, Keith Humphreys, Peter Devilee, Robert AEM Tollenaar, Caroline Seynaeve, Paolo Radice, Paolo Peterlongo, Siranoush Manoukian, Filomena Ficarazzi, Matthias W Beckmann, Alexander Hein, Arif B Ekici, Rosemary Balleine, Kelly-Anne Phillips, Javier Benitez, M Pilar Zamora, Jose Ignacio Arias Perez, Primitiva Menéndez, Anna Jakubowska, Jan Lubinski, Jacek Gronwald, Katarzyna Durda, Ute Hamann, Maria Kabisch, Hans Ulrich Ulmer, Thomas Rüdiger, Sara Margolin, Vessela Kristensen, Siljie Nord, D Gareth Evans, Jean Abraham, Helena Earl, Christopher J Poole, Louise Hiller, Janet A Dunn, Sarah Bowden, Rose Yang, Daniele Campa, W Ryan Diver, Susan M Gapstur, Mia M Gaudet, Susan Hankinson, Robert N Hoover, Anika Hüsing, Rudolf Kaaks, Mitchell J Machiela, Walter Willett, Myrto Barrdahl, Federico Canzian, Suet-Feung Chin, Carlos Caldas, David J Hunter, Sara Lindstrom, Montserrat Garcia-Closas, Fergus J Couch, Georgia Chenevix-Trench, Arto Mannermaa, Irene L Andrulis, Per Hall, Jenny Chang-Claude, Douglas F Easton, Stig E Bojesen, Angela Cox, Peter A Fasching, Paul DP Pharoah, Marjanka K Schmidt
Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents
Christy C Ong, Sarah Gierke, Cameron Pitt, Meredith Sagolla, Christine K Cheng, Wei Zhou, Adrian M Jubb, Laura Strickland, Maike Schmidt, Sergio G Duron, David A Campbell, Wei Zheng, Seameen Dehdashti, Min Shen, Nora Yang, Mark L Behnke, Wenwei Huang, John C McKew, Jonathan Chernoff, William F Forrest, Peter M Haverty, Suet-Feung Chin, Emad A Rakha, Andrew R Green, Ian O Ellis, Carlos Caldas, Thomas O’Brien, Lori S Friedman, Hartmut Koeppen, Joachim Rudolph, Klaus P Hoeflich
Molecular characterization and targeted therapeutic approaches in breast cancer
Angela Toss, Massimo Cristofanilli
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers
Sophie Blein, Claire Bardel, Vincent Danjean, Lesley McGuffog, Sue Healey, Daniel Barrowdale, Andrew Lee, Joe Dennis, Karoline B Kuchenbaecker, Penny Soucy, Mary Beth Terry, Wendy K Chung, David E Goldgar, Saundra S Buys, Ramunas Janavicius, Laima Tihomirova, Nadine Tung, Cecilia M Dorfling, Elizabeth J van Rensburg, Susan L Neuhausen, Yuan Chun Ding, Anne-Marie Gerdes, Bent Ejlertsen, Finn C Nielsen, Thomas VO Hansen, Ana Osorio, Javier Benitez, Raquel Andrés Conejero, Ena Segota, Jeffrey N Weitzel, Margo Thelander, Paolo Peterlongo, Paolo Radice, Valeria Pensotti, Riccardo Dolcetti, Bernardo Bonanni, Bernard Peissel, Daniela Zaffaroni, Giulietta Scuvera, Siranoush Manoukian, Liliana Varesco, Gabriele L Capone, Laura Papi, Laura Ottini, Drakoulis Yannoukakos, Irene Konstantopoulou, Judy Garber, Ute Hamann, Alan Donaldson, Angela Brady, Carole Brewer, Claire Foo, D Gareth Evans, Debra Frost, Diana Eccles, Fiona Douglas, Jackie Cook, Julian Adlard, Julian Barwell, Lisa Walker, Louise Izatt, Lucy E Side, M John Kennedy, Marc Tischkowitz, Mark T Rogers, Mary E Porteous, Patrick J Morrison, Radka Platte, Ros Eeles, Rosemarie Davidson, Shirley Hodgson, Trevor Cole, Andrew K Godwin, Claudine Isaacs, Kathleen Claes, Kim De Leeneer, Alfons Meindl, Andrea Gehrig, Barbara Wappenschmidt, Christian Sutter, Christoph Engel, Dieter Niederacher, Doris Steinemann, Hansjoerg Plendl, Karin Kast, Kerstin Rhiem, Nina Ditsch, Norbert Arnold, Raymonda Varon-Mateeva, Rita K Schmutzler, Sabine Preisler-Adams, Nadja Bogdanova Markov, Shan Wang-Gohrke, Antoine de Pauw, Cédrick Lefol, Christine Lasset, Dominique Leroux, Etienne Rouleau, Francesca Damiola, Hélène Dreyfus, Laure Barjhoux, Lisa Golmard, Nancy Uhrhammer, Valérie Bonadona, Valérie Sornin, Yves-Jean Bignon, Jonathan Carter, Linda Van Le, Marion Piedmonte, Paul A DiSilvestro, Miguel de la Hoya, Trinidad Caldes, Heli Nevanlinna, Kristiina Aittomäki, Agnes Jager, Ans MW van den Ouweland, Carolien M Kets, Cora M Aalfs, Flora E van Leeuwen, Frans BL Hogervorst, Hanne EJ Meijers-Heijboer, Jan C Oosterwijk, Kees EP van Roozendaal, Matti A Rookus, Peter Devilee, Rob B van der Luijt, Edith Olah, Orland Diez, Alex Teulé, Conxi Lazaro, Ignacio Blanco, Jesús Del Valle, Anna Jakubowska, Grzegorz Sukiennicki, Jacek Gronwald, Jan Lubinski, Katarzyna Durda, Katarzyna Jaworska-Bieniek, Bjarni A Agnarsson, Christine Maugard, Alberto Amadori, Marco Montagna, Manuel R Teixeira, Amanda B Spurdle, William Foulkes, Curtis Olswold, Noralane M Lindor, Vernon S Pankratz, Csilla I Szabo, Anne Lincoln, Lauren Jacobs, Marina Corines, Mark Robson, Joseph Vijai, Andreas Berger, Anneliese Fink-Retter, Christian F Singer, Christine Rappaport, Daphne Geschwantler Kaulich, Georg Pfeiler, Muy-Kheng Tea, Mark H Greene, Phuong L Mai, Gad Rennert, Evgeny N Imyanitov, Anna Marie Mulligan, Gord Glendon, Irene L Andrulis, Sandrine Tchatchou, Amanda Ewart Toland, Inge Sokilde Pedersen, Mads Thomassen, Torben A Kruse, Uffe Birk Jensen, Maria A Caligo, Eitan Friedman, Jamal Zidan, Yael Laitman, Annika Lindblom, Beatrice Melin, Brita Arver, Niklas Loman, Richard Rosenquist, Olufunmilayo I Olopade, Robert L Nussbaum, Susan J Ramus, Katherine L Nathanson, Susan M Domchek, Timothy R Rebbeck, Banu K Arun, Gillian Mitchell, Beth Y Karlan, Jenny Lester, Sandra Orsulic, Dominique Stoppa-Lyonnet, Gilles Thomas, Jacques Simard, Fergus J Couch, Kenneth Offit, Douglas F Easton, Georgia Chenevix-Trench, Antonis C Antoniou, Sylvie Mazoyer, Catherine M Phelan, Olga M Sinilnikova, David G Cox
Omega-3 fatty acids for breast cancer prevention and survivorship
Carol J Fabian, Bruce F Kimler, Stephen D Hursting
Benefits and harms of mammography screening
Magnus Løberg, Mette Lise Lousdal, Michael Bretthauer, Mette Kalager
Metformin increases survival in hormone receptor-positive, HER2-positive breast cancer patients with diabetes
Hee Jeong Kim, Hyunwook Kwon, Jong Won Lee, Hwa Jung Kim, Sae Byul Lee, Hee Sung Park, Guiyun Sohn, Yura Lee, Beom Seok Koh, Jong Han Yu, Byung Ho Son, Sei Hyun Ahn
Low ATM protein expression in malignant tumor as well as cancer-associated stroma are independent prognostic factors in a retrospective study of early-stage hormone-negative breast cancer
Xiaolan Feng, Haocheng Li, Michelle Dean, Holly E Wilson, Elizabeth Kornaga, Emeka K Enwere, Patricia Tang, Alexander Paterson, Susan P Lees-Miller, Anthony M Magliocco, Gwyn Bebb
Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery
Susanne Kossatz, Julia Grandke, Pierre Couleaud, Alfonso Latorre, Antonio Aires, Kieran Crosbie-Staunton, Robert Ludwig, Heidi Dähring, Volker Ettelt, Ana Lazaro-Carrillo, Macarena Calero, Maha Sader, José Courty, Yuri Volkov, Adriele Prina-Mello, Angeles Villanueva, Álvaro Somoza, Aitziber L Cortajarena, Rodolfo Miranda, Ingrid Hilger
Quantitative assessment of background parenchymal enhancement in breast MRI predicts response to risk-reducing salpingo-oophorectomy: preliminary evaluation in a cohort of BRCA1/2 mutation carriers
Shandong Wu, Susan P Weinstein, Michael J DeLeo III, Emily F Conant, Jinbo Chen, Susan M Domchek, Despina Kontos
Anti-CCL2: building a reservoir or opening the floodgates to metastasis?
Jessica R Hitchcock, Christine J Watson
Acquisition of epithelial-mesenchymal transition phenotype in the tamoxifen-resistant breast cancer cell: a new role for G protein-coupled estrogen receptor in mediating tamoxifen resistance through cancer-associated fibroblast-derived fibronectin and β1-integrin signaling pathway in tumor cells
Jie Yuan, Manran Liu, Li Yang, Gang Tu, Qing Zhu, Maoshan Chen, Hong Cheng, Haojun Luo, Weijie Fu, Zhenhua Li, Guanglun Yang
Interleukin-15 is required for immunosurveillance and immunoprevention of HER2/neu-driven mammary carcinogenesis
Stefania Croci, Patrizia Nanni, Arianna Palladini, Giordano Nicoletti, Valentina Grosso, Giorgia Benegiamo, Lorena Landuzzi, Alessia Lamolinara, Marianna L. Ianzano, Dario Ranieri, Massimiliano Dall’Ora, Manuela Iezzi, Carla De Giovanni, Pier-Luigi Lollini
Anti-HER2 CD4+ T-helper type 1 response is a novel immune correlate to pathologic response following neoadjuvant therapy in HER2-positive breast cancer
Jashodeep Datta, Erik Berk, Shuwen Xu, Elizabeth Fitzpatrick, Cinthia Rosemblit, Lea Lowenfeld, Noah Goodman, David A Lewis, Paul J Zhang, Carla Fisher, Robert E Roses, Angela DeMichele, Brian J Czerniecki
Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures
So Hyun Chung, Michael D. Feldman, Daniel Martinez, Helen Kim, Mary E. Putt, David R. Busch, Julia Tchou, Brian J. Czerniecki, Mitchell D. Schnall, Mark A. Rosen, Angela DeMichele, Arjun G. Yodh, Regine Choe
Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response
Mark Jesus M. Magbanua, Denise M. Wolf, Christina Yau, Sarah E. Davis, Julia Crothers, Alfred Au, Christopher M. Haqq, Chad Livasy, Hope S. Rugo, Laura Esserman, John W. Park, Laura J. van ’t Veer
The effect of weight change on changes in breast density measures over menopause in a breast cancer screening cohort
Johanna Olga Pauline Wanders, Marije Fokje Bakker, Wouter Bernard Veldhuis, Petra Huberdina Maria Peeters, Carla Henrica van Gils
Identification of two novel mammographic density loci at 6Q25.1
Judith S Brand, Jingmei Li, Keith Humphreys, Robert Karlsson, Mikael Eriksson, Emma Ivansson, Per Hall, Kamila Czene
Molecular drivers of lobular carcinoma in situ
Greg J. Logan, David J. Dabbs, Peter C. Lucas, Rachel C. Jankowitz, Daniel D. Brown, Beth Z. Clark, Steffi Oesterreich, Priscilla F. McAuliffe
Adolescent endogenous sex hormones and breast density in early adulthood
Seungyoun Jung, Brian L. Egleston, D. Walt Chandler, Linda Van Horn, Nola M. Hylton, Catherine C. Klifa, Norman L. Lasser, Erin S. LeBlanc, Kenneth Paris, John A. Shepherd, Linda G. Snetselaar, Frank Z. Stanczyk, Victor J. Stevens, Joanne F. Dorgan
CD24+ cells fuel rapid tumor growth and display high metastatic capacity
Ran Rostoker, Sagi Abelson, Inna Genkin, Sarit Ben-Shmuel, Ravi Sachidanandam, Eyal J. Scheinman, Keren Bitton-Worms, Zila Shen Orr, Avishay Caspi, Maty Tzukerman, Derek LeRoith
High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium
Cecilia W. Huo, Grace Chew, Prue Hill, Dexing Huang, Wendy Ingman, Leigh Hodson, Kristy A. Brown, Astrid Magenau, Amr H. Allam, Ewan McGhee, Paul Timpson, Michael A. Henderson, Erik W. Thompson, Kara Britt
Appraisal of the technologies and review of the genomic landscape of ductal carcinoma in situ of the breast
Jia-Min B. Pang, Kylie L. Gorringe, Stephen Q. Wong, Alexander Dobrovic, Ian G. Campbell, Stephen B. Fox
Genetic risk variants associated with in situ breast cancer
Daniele Campa, Myrto Barrdahl, Mia M. Gaudet, Amanda Black, Stephen J. Chanock, W. Ryan Diver, Susan M. Gapstur, Christopher Haiman, Susan Hankinson, Aditi Hazra, Brian Henderson, Robert N. Hoover, David J. Hunter, Amit D. Joshi, Peter Kraft, Loic Le Marchand, Sara Lindström, Walter Willett, Ruth C. Travis, Pilar Amiano, Afshan Siddiq, Dimitrios Trichopoulos, Malin Sund, Anne Tjønneland, Elisabete Weiderpass, Petra H. Peeters, Salvatore Panico, Laure Dossus, Regina G. Ziegler, Federico Canzian, Rudolf Kaaks
MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene
Yu Wei Phua, Akira Nguyen, Daniel L. Roden, Benjamin Elsworth, Niantao Deng, Iva Nikolic, Jessica Yang, Andrea Mcfarland, Roslin Russell, Warren Kaplan, Mark J. Cowley, Radhika Nair, Elena Zotenko, Sandra O’Toole, Shi-xiong Tan, David E. James, Susan J. Clark, Hosein Kouros-Mehr, Alexander Swarbrick
Can the breast screening appointment be used to provide risk assessment and prevention advice?
D. Gareth Evans, Anthony Howell
Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits
Bhupinder Pal, Yunshun Chen, Andrew Bert, Yifang Hu, Julie M. Sheridan, Tamara Beck, Wei Shi, Keith Satterley, Paul Jamieson, Gregory J. Goodall, Geoffrey J. Lindeman, Gordon K. Smyth, Jane E. Visvader
PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2+ breast cancer cells by inducing Bim
Sun Hee Park, Koichi Ito, William Olcott, Igor Katsyv, Gwyneth Halstead-Nussloch, Hanna Y. Irie
Erratum to: Elafin is downregulated during breast and ovarian tumorigenesis but its residual expression predicts recurrence
Joseph A Caruso, Cansu Karakas, Jing Zhang, Min Yi, Constance Albarracin, Aysegul Sahin, Melissa Bondy, Jinsong Liu, Kelly K. Hunt, Khandan Keyomarsi
Metformin in breast cancer - an evolving mystery
Laura Camacho, Atreyi Dasgupta, Sao Jiralerspong
Arthralgia among women taking aromatase inhibitors: is there a shared inflammatory mechanism with co-morbid fatigue and insomnia?
Joshua Bauml, Lu Chen, Jinbo Chen, Jean Boyer, Michael Kalos, Susan Q. Li, Angela DeMichele, Jun J. Mao
Reduced proliferation in breast cancer cells contacting the neighboring adipocytes in human breast cancer tissues
Han Suk Ryu, Han-Byoel Lee, Wonshik Han, Dong-Young Noh, Hyeong-Gon Moon
Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance
Shenduo Li, Sturgis Payne, Fang Wang, Peter Claus, Zuowei Su, Jeffrey Groth, Joseph Geradts, Gustaaf de Ridder, Rebeca Alvarez, Paul Kelly Marcom, Salvatore V. Pizzo, Robin E. Bachelder
Tipping the balance between good and evil: aberrant 14-3-3ζ expression drives oncogenic TGF-β signaling in metastatic breast cancers
Chevaun D. Morrison, William P. Schiemann
Mammographic density and breast cancer in women from high risk families
Teresa Ramón y Cajal, Isabel Chirivella, Josefa Miranda, Alexandre Teule, Ángel Izquierdo, Judith Balmaña, Ana Beatriz Sánchez-Heras, Gemma Llort, David Fisas, Virginia Lope, Elena Hernández-Agudo, María José Juan-Fita, Isabel Tena, Luis Robles, Carmen Guillén-Ponce, Pedro Pérez-Segura, Mari Sol Luque-Molina, Susana Hernando-Polo, Mónica Salinas, Joan Brunet, María Dolores Salas-Trejo, Agustí Barnadas, Marina Pollán
Body fatness during childhood and adolescence and breast density in young women: a prospective analysis
Kimberly A. Bertrand, Heather J. Baer, E. John Orav, Catherine Klifa, John A. Shepherd, Linda Van Horn, Linda Snetselaar, Victor J. Stevens, Nola M. Hylton, Joanne F. Dorgan
Erratum to: Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL
Luke Piggott, Nader Omidvar, Salvador Martí Pérez, Rhiannon French, Matthias Eberl, Richard WE Clarkson
Alternative signaling network activation through different insulin receptor family members caused by pro-mitogenic antidiabetic insulin analogues in human mammary epithelial cells
Bas ter Braak, Steven Wink, Esmee Koedoot, Chantal Pont, Christine Siezen, Jan Willem van der Laan, Bob van de Water
Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis
Panagiotis Papageorgis, Sait Ozturk, Arthur W. Lambert, Christiana M. Neophytou, Alexandros Tzatsos, Chen K. Wong, Sam Thiagalingam, Andreas I. Constantinou
Lobular breast cancer - the most common special subtype or a most special common subtype?
Ulrich Lehmann
Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence
Heleen K Bronsveld, Bas ter Braak, Øystein Karlstad, Peter Vestergaard, Jakob Starup-Linde, Marloes T Bazelier, Marie L De Bruin, Anthonius de Boer, Christine L E Siezen, Bob van de Water, Jan Willem van der Laan, Marjanka K Schmidt
Human breast cancer cells educate macrophages toward the M2 activation status
Sofia Sousa, Régis Brion, Minnamaija Lintunen, Pauliina Kronqvist, Jouko Sandholm, Jukka Mönkkönen, Pirkko-Liisa Kellokumpu-Lehtinen, Susanna Lauttia, Olli Tynninen, Heikki Joensuu, Dominique Heymann, Jorma A. Määttä
Contralateral breast cancer can represent a metastatic spread of the first primary tumor: determination of clonal relationship between contralateral breast cancers using next-generation whole genome sequencing
Sara Alkner, Man-Hung Eric Tang, Christian Brueffer, Malin Dahlgren, Yilun Chen, Eleonor Olsson, Christof Winter, Sara Baker, Anna Ehinger, Lisa Rydén, Lao H. Saal, Mårten Fernö, Sofia K. Gruvberger-Saal
Alcohol consumption, endogenous estrogen and mammographic density among premenopausal women
Hanne Frydenberg, Vidar G. Flote, Ine M. Larsson, Emily S. Barrett, Anne-Sofie Furberg, Giske Ursin, Tom Wilsgaard, Peter T. Ellison, Anne McTiernan, Anette Hjartåker, Grazyna Jasienska, Inger Thune
The molecular landscape of premenopausal breast cancer
Serena Liao, Ryan J. Hartmaier, Kandace P. McGuire, Shannon L. Puhalla, Soumya Luthra, Uma R. Chandran, Tianzhou Ma, Rohit Bhargava, Francesmary Modugno, Nancy E. Davidson, Steve Benz, Adrian V. Lee, George C. Tseng, Steffi Oesterreich
Micro-anatomical quantitative optical imaging: toward automated assessment of breast tissues
Jessica L. Dobbs, Jenna L. Mueller, Savitri Krishnamurthy, Dongsuk Shin, Henry Kuerer, Wei Yang, Nirmala Ramanujam, Rebecca Richards-Kortum
Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence
Beatriz Morancho, Águeda Martínez-Barriocanal, Josep Villanueva, Joaquín Arribas
Targeting lysyl oxidase for molecular imaging in breast cancer
Melinda Wuest, Manuela Kuchar, Sai Kiran Sharma, Susan Richter, Ingrit Hamann, Monica Wang, Larissa Vos, John R. Mackey, Frank Wuest, Reik Löser
Chromosomal copy number alterations for associations of ductal carcinoma in situ with invasive breast cancer
Anosheh Afghahi, Erna Forgó, Aya A. Mitani, Manisha Desai, Sushama Varma, Tina Seto, Joseph Rigdon, Kristin C. Jensen, Megan L. Troxell, Scarlett Lin Gomez, Amar K. Das, Andrew H. Beck, Allison W. Kurian, Robert B. West
Decoding breast cancer tissue–stroma interactions using species-specific sequencing
Indira V. Chivukula, Daniel Ramsköld, Helena Storvall, Charlotte Anderberg, Shaobo Jin, Veronika Mamaeva, Cecilia Sahlgren, Kristian Pietras, Rickard Sandberg, Urban Lendahl
A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density
Anja Rudolph, Peter A. Fasching, Sabine Behrens, Ursula Eilber, Manjeet K. Bolla, Qin Wang, Deborah Thompson, Kamila Czene, Judith S. Brand, Jingmei Li, Christopher Scott, V. Shane Pankratz, Kathleen Brandt, Emily Hallberg, Janet E. Olson, Adam Lee, Matthias W. Beckmann, Arif B. Ekici, Lothar Haeberle, Gertraud Maskarinec, Loic Le Marchand, Fredrick Schumacher, Roger L. Milne, Julia A. Knight, Carmel Apicella, Melissa C. Southey, Miroslav K. Kapuscinski, John L. Hopper, Irene L. Andrulis, Graham G. Giles, Christopher A. Haiman, Kay-Tee Khaw, Robert Luben, Per Hall, Paul D. P. Pharoah, Fergus J. Couch, Douglas F. Easton, Isabel dos-Santos-Silva, Celine Vachon, Jenny Chang-Claude
Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls
Ella R. Thompson, Kylie L. Gorringe, Simone M. Rowley, Michelle W. Wong-Brown, Simone McInerny, Na Li, Alison H. Trainer, Lisa Devereux, Maria A. Doyle, Jason Li, Richard Lupat, Martin B. Delatycki, Gillian Mitchell, Paul A. James, Rodney J. Scott, Ian G. Campbell
Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers
Amy L. Strong, Jason F. Ohlstein, Brandi A. Biagas, Lyndsay V. Rhodes, Dorothy T. Pei, H. Alan Tucker, Claire Llamas, Annie C. Bowles, Maria F. Dutreil, Shijia Zhang, Jeffrey M. Gimble, Matthew E. Burow, Bruce A. Bunnell
Expression of truncated human epidermal growth factor receptor 2 on circulating tumor cells of breast cancer patients
Galatea Kallergi, Sofia Agelaki, Maria A. Papadaki, Dimitris Nasias, Alexios Matikas, Dimitris Mavroudis, Vassilis Georgoulias
Assessing breast cancer cell lines as tumour models by comparison of mRNA expression profiles
Krista Marie Vincent, Scott D. Findlay, Lynne Marie Postovit
Lack of epidermal growth factor receptor (EGFR)-activating mutations in triple-negative breast cancer in China
Wen-Ming Cao, Yun Gao, Xiao-Jia Wang
Breast cancer tumour growth modelling for studying the association of body size with tumour growth rate and symptomatic detection using case-control data
Linda Abrahamsson, Kamila Czene, Per Hall, Keith Humphreys
Preliminary evaluation of the publicly available Laboratory for Breast Radiodensity Assessment (LIBRA) software tool: comparison of fully automated area and volumetric density measures in a case–control study with digital mammography
Brad M. Keller, Jinbo Chen, Dania Daye, Emily F. Conant, Despina Kontos
The seventh ENBDC workshop on methods in mammary gland development and cancer
Marina A. Glukhova, Nancy Hynes, Maria dM Vivanco, Renée van Amerongen, Robert B. Clarke, Mohamed Bentires-Alj
Effect of weight loss, with or without exercise, on body composition and sex hormones in postmenopausal women: the SHAPE-2 trial
Willemijn AM. van Gemert, Albertine J. Schuit, Job van der Palen, Anne M. May, Jolein A. Iestra, Harriet Wittink, Petra H. Peeters, Evelyn M. Monninkhof
Bisphosphonates as anticancer agents in early breast cancer: preclinical and clinical evidence
Daniele Santini, Luciano Stumbo, Chiara Spoto, Loretta D’Onofrio, Francesco Pantano, Michele Iuliani, Marco fioramonti, Alice Zoccoli, Giulia Ribelli, Vladimir Virzì, Bruno Vincenzi, Giuseppe Tonini
Prosaposin activates the androgen receptor and potentiates resistance to endocrine treatment in breast cancer
Azlena Ali, Laura Creevey, Yuan Hao, Damian McCartan, Peadar O’Gaora, Arnold Hill, Leonie Young, Marie McIlroy
Prognostic significance of tumor-infiltrating CD8+ and FOXP3+ lymphocytes in residual tumors and alterations in these parameters after neoadjuvant chemotherapy in triple-negative breast cancer: a retrospective multicenter study
Minoru Miyashita, Hironobu Sasano, Kentaro Tamaki, Hisashi Hirakawa, Yayoi Takahashi, Saki Nakagawa, Gou Watanabe, Hiroshi Tada, Akihiko Suzuki, Noriaki Ohuchi, Takanori Ishida
Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer
Melanie Spitzwieser, Elisabeth Holzweber, Georg Pfeiler, Stefan Hacker, Margit Cichna-Markl
Erratum to: Humanization of the mouse mammary gland by replacement of the luminal layer with genetically engineered preneoplastic human cells
Stephanie Verbeke, Elodie Richard, Elodie Monceau, Xenia Schmidt, Benoit Rousseau, Valerie Velasco, David Bernard, Herve Bonnefoi, Gaetan MacGrogan, Richard D Iggo
ALK alteration is a frequent event in aggressive breast cancers
Abdul K. Siraj, Shaham Beg, Zeenath Jehan, Sarita Prabhakaran, Maqbool Ahmed, Azhar R.Hussain, Fouad Al-Dayel, Asma Tulbah, Dahish Ajarim, Khawla S. Al-Kuraya
Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion
Hanan S. Elsarraj, Yan Hong, Kelli E. Valdez, Whitney Michaels, Marcus Hook, William P. Smith, Jeremy Chien, Jason I. Herschkowitz, Melissa A. Troester, Moriah Beck, Marc Inciardi, Jason Gatewood, Lisa May, Therese Cusick, Marilee McGinness, Lawrence Ricci, Fang Fan, Ossama Tawfik, Jeffrey R. Marks, Jennifer R. Knapp, Hung-Wen Yeh, Patricia Thomas, D. R. Carrasco, Timothy A. Fields, Andrew K. Godwin, Fariba Behbod
The influence of obesity on survival in early, high-risk breast cancer: results from the randomized SUCCESS A trial
Peter Widschwendter, Thomas WP Friedl, Lukas Schwentner, Nikolaus DeGregorio, Bernadette Jaeger, Amelie Schramm, Inga Bekes, Miriam Deniz, Krisztian Lato, Tobias Weissenbacher, Bernd Kost, Ulrich Andergassen, Julia Jueckstock, Julia Neugebauer, Elisabeth Trapp, Peter A. Fasching, Matthias W. Beckmann, Andreas Schneeweiss, Ines Schrader, Brigitte Rack, Wolfgang Janni, Christoph Scholz
Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer
Meliha Mehmeti, Roni Allaoui, Caroline Bergenfelz, Lao H. Saal, Stephen P. Ethier, Martin E. Johansson, Karin Jirström, Karin Leandersson
An ecological measure of immune-cancer colocalization as a prognostic factor for breast cancer
Carlo C. Maley, Konrad Koelble, Rachael Natrajan, Athena Aktipis, Yinyin Yuan
Transformation of enriched mammary cell populations with polyomavirus middle T antigen influences tumor subtype and metastatic potential
Daria Drobysheva, Brittni Alise Smith, Maria McDowell, Katrin P. Guillen, Huseyin Atakan Ekiz, Bryan E. Welm
The relationship between quantitative human epidermal growth factor receptor 2 gene expression by the 21-gene reverse transcriptase polymerase chain reaction assay and adjuvant trastuzumab benefit in Alliance N9831
Edith A. Perez, Frederick L. Baehner, Steven M. Butler, E. Aubrey Thompson, Amylou C. Dueck, Farid Jamshidian, Diana Cherbavaz, Carl Yoshizawa, Steven Shak, Peter A. Kaufman, Nancy E. Davidson, Julie Gralow, Yan W. Asmann, Karla V. Ballman
Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response
Esther H. Lips, Magali Michaut, Marlous Hoogstraat, Lennart Mulder, Nicolle JM Besselink, Marco J. Koudijs, Edwin Cuppen, Emile E. Voest, Rene Bernards, Petra M. Nederlof, Jelle Wesseling, Sjoerd Rodenhuis, Lodewyk FA Wessels
Tumor-induced inflammation alters neutrophil phenotype and disease progression
Charaf Benarafa
Multipotent luminal mammary cancer stem cells model tumor heterogeneity
Lei Bao, Robert D. Cardiff, Paul Steinbach, Karen S. Messer, Lesley G. Ellies
Puberty-specific promotion of mammary tumorigenesis by a high animal fat diet
Mark D. Aupperlee, Yong Zhao, Ying Siow Tan, Yirong Zhu, Ingeborg M. Langohr, Erin L. Kirk, Jason R. Pirone, Melissa A. Troester, Richard C. Schwartz, Sandra Z. Haslam
Effect of physical activity on sex hormones in women: a systematic review and meta-analysis of randomized controlled trials
Kaoutar Ennour-Idrissi, Elizabeth Maunsell, Caroline Diorio
The benefit of HER2-targeted therapies on overall survival of patients with metastatic HER2-positive breast cancer – a systematic review
Diogo Mendes, Carlos Alves, Noémia Afonso, Fátima Cardoso, José Luís Passos-Coelho, Luís Costa, Sofia Andrade, Francisco Batel-Marques
Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer
Xue B. Holdman, Thomas Welte, Kimal Rajapakshe, Adam Pond, Cristian Coarfa, Qianxing Mo, Shixia Huang, Susan G. Hilsenbeck, Dean P. Edwards, Xiang Zhang, Jeffrey M. Rosen
Mammographic density defined by higher than conventional brightness threshold better predicts breast cancer risk for full-field digital mammograms
Tuong Linh Nguyen, Ye Kyaw Aung, Christopher Francis Evans, Choi Yoon-Ho, Mark Anthony Jenkins, Joohon Sung, John Llewelyn Hopper, Yun-Mi Song
Longer term effects of the Angelina Jolie effect: increased risk-reducing mastectomy rates in BRCA carriers and other high-risk women
D. Gareth Evans, Julie Wisely, Tara Clancy, Fiona Lalloo, Mary Wilson, Richard Johnson, Jonathon Duncan, Lester Barr, Ashu Gandhi, Anthony Howell
Erratum to: Quantitative assessment of background parenchymal enhancement in breast MRI predicts response to risk-reducing salpingo-oophorectomy: preliminary evaluation in a cohort of BRCA1/2 mutation carriers
Shandong Wu, Susan P. Weinstein, Michael J. DeLeo, Emily F. Conant, Jinbo Chen, Susan M. Domchek, Despina Kontos
β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion
Sarah J. Creed, Caroline P. Le, Mona Hassan, Cindy K. Pon, Sabine Albold, Keefe T. Chan, Matthew E. Berginski, Zhendong Huang, James E. Bear, J. Robert Lane, Michelle L. Halls, Davide Ferrari, Cameron J. Nowell, Erica K. Sloan
The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features
Andrea Aloia, Evgeniya Petrova, Stefan Tomiuk, Ute Bissels, Olivier Déas, Massimo Saini, Franziska Maria Zickgraf, Steve Wagner, Saskia Spaich, Marc Sütterlin, Andreas Schneeweiss, Manuel Reitberger, Silvia Rüberg, Bernhard Gerstmayer, David Agorku, Sebastian Knöbel, Annalisa Terranegra, Monica Falleni, Laura Soldati, Martin Ronald Sprick, Andreas Trumpp, Jean-Gabriel Judde, Andreas Bosio, Stefano Cairo, Olaf Hardt
Mammographic density adds accuracy to both the Tyrer-Cuzick and Gail breast cancer risk models in a prospective UK screening cohort
Adam R. Brentnall, Elaine F. Harkness, Susan M. Astley, Louise S. Donnelly, Paula Stavrinos, Sarah Sampson, Lynne Fox, Jamie C. Sergeant, Michelle N. Harvie, Mary Wilson, Ursula Beetles, Soujanya Gadde, Yit Lim, Anil Jain, Sara Bundred, Nicola Barr, Valerie Reece, Anthony Howell, Jack Cuzick, D. Gareth R. Evans
Dual inhibition of Type I and Type III PI3 kinases increases tumor cell apoptosis in HER2+ breast cancers
Christian D. Young, Carlos L. Arteaga, Rebecca S. Cook
HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers
Preeti Putcha, Jiyang Yu, Ruth Rodriguez-Barrueco, Laura Saucedo-Cuevas, Patricia Villagrasa, Eva Murga-Penas, Steven N. Quayle, Min Yang, Veronica Castro, David Llobet-Navas, Daniel Birnbaum, Pascal Finetti, Wendy A. Woodward, François Bertucci, Mary L. Alpaugh, Andrea Califano, Jose Silva
“New” metastases are associated with a poorer prognosis than growth of pre-existing metastases in patients with metastatic breast cancer treated with chemotherapy
Christopher Twelves, Javier Cortes, Peter A. Kaufman, Louise Yelle, Ahmad Awada, Terri A. Binder, Martin Olivo, James Song, Joyce A. O’Shaughnessy, Maria Jove, Edith A. Perez