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Zeitschrift

Breast Cancer Research

Breast Cancer Research 1/2018

Ausgabe 1/2018

Inhaltsverzeichnis ( 155 Artikel )

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

SNPs related to vitamin D and breast cancer risk: a case-control study

Linnea Huss, Salma Tunå Butt, Peter Almgren, Signe Borgquist, Jasmine Brandt, Asta Försti, Olle Melander, Jonas Manjer

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model

Sreeraj G. Pillai, Shunqiang Li, Chidananda M. Siddappa, Matthew J Ellis, Mark A. Watson, Rebecca Aft

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs

Na Li, Simone M. Rowley, Ella R. Thompson, Simone McInerny, Lisa Devereux, Kaushalya C. Amarasinghe, Magnus Zethoven, Richard Lupat, David Goode, Jason Li, Alison H. Trainer, Kylie L. Gorringe, Paul A. James, Ian G. Campbell

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Selective serotonin reuptake inhibitor use and breast cancer survival: a population-based cohort study

John Busby, Ken Mills, Shu-Dong Zhang, Fabio Giuseppe Liberante, Chris R. Cardwell

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Body mass index at age 18 years and recent body mass index in relation to risk of breast cancer overall and ER/PR/HER2-defined subtypes in white women and African-American women: a pooled analysis

Huiyan Ma, Giske Ursin, Xinxin Xu, Eunjung Lee, Kayo Togawa, Kathleen E. Malone, Polly A. Marchbanks, Jill A. McDonald, Michael S. Simon, Suzanne G. Folger, Yani Lu, Jane Sullivan-Halley, Dennis M. Deapen, Michael F. Press, Leslie Bernstein

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Inherited factors contribute to an inverse association between preeclampsia and breast cancer

Haomin Yang, Wei He, Mikael Eriksson, Jingmei Li, Natalie Holowko, Flaminia Chiesa, Per Hall, Kamila Czene

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer

Nana Weber-Lassalle, Jan Hauke, Juliane Ramser, Lisa Richters, Eva Groß, Britta Blümcke, Andrea Gehrig, Anne-Karin Kahlert, Clemens R. Müller, Karl Hackmann, Ellen Honisch, Konstantin Weber-Lassalle, Dieter Niederacher, Julika Borde, Holger Thiele, Corinna Ernst, Janine Altmüller, Guido Neidhardt, Peter Nürnberg, Kristina Klaschik, Christopher Schroeder, Konrad Platzer, Alexander E. Volk, Shan Wang-Gohrke, Walter Just, Bernd Auber, Christian Kubisch, Gunnar Schmidt, Judit Horvath, Barbara Wappenschmidt, Christoph Engel, Norbert Arnold, Bernd Dworniczak, Kerstin Rhiem, Alfons Meindl, Rita K. Schmutzler, Eric Hahnen

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors

Anneleen Daemen, Gerard Manning

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion

Matthew G. Annis, Veronique Ouellet, Jonathan P. Rennhack, Sylvain L’Esperance, Claudine Rancourt, Anne-Marie Mes-Masson, Eran R. Andrechek, Peter M. Siegel

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

A comparison of five methods of measuring mammographic density: a case-control study

Susan M. Astley, Elaine F. Harkness, Jamie C. Sergeant, Jane Warwick, Paula Stavrinos, Ruth Warren, Mary Wilson, Ursula Beetles, Soujanya Gadde, Yit Lim, Anil Jain, Sara Bundred, Nicola Barr, Valerie Reece, Adam R. Brentnall, Jack Cuzick, Tony Howell, D. Gareth Evans

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

The significance of tumour microarchitectural features in breast cancer prognosis: a digital image analysis

I. Roxanis, R. Colling, C. Kartsonaki, A. R. Green, E A. Rakha

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Frequency of breast cancer subtypes among African American women in the AMBER consortium

Emma H. Allott, Joseph Geradts, Stephanie M. Cohen, Thaer Khoury, Gary R. Zirpoli, Wiam Bshara, Warren Davis, Angela Omilian, Priya Nair, Rochelle P. Ondracek, Ting-Yuan David Cheng, C. Ryan Miller, Helena Hwang, Leigh B. Thorne, Siobhan O’Connor, Traci N. Bethea, Mary E. Bell, Zhiyuan Hu, Yan Li, Erin L. Kirk, Xuezheng Sun, Edward A. Ruiz-Narvaez, Charles M. Perou, Julie R. Palmer, Andrew F. Olshan, Christine B. Ambrosone, Melissa A. Troester

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Not all false positive diagnoses are equal: On the prognostic implications of false-positive diagnoses made in breast MRI versus in mammography / digital tomosynthesis screening

Christiane K. Kuhl, Annika Keulers, Kevin Strobel, Hannah Schneider, Nadine Gaisa, Simone Schrading

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Affinity proteomic profiling of plasma for proteins associated to area-based mammographic breast density

Sanna Byström, Martin Eklund, Mun-Gwan Hong, Claudia Fredolini, Mikael Eriksson, Kamila Czene, Per Hall, Jochen M. Schwenk, Marike Gabrielson

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Prognostic impact of CD4-positive T cell subsets in early breast cancer: a study based on the FinHer trial patient population

Marcus Schmidt, Veronika Weyer-Elberich, Jan G. Hengstler, Anne-Sophie Heimes, Katrin Almstedt, Aslihan Gerhold-Ay, Antje Lebrecht, Marco J. Battista, Annette Hasenburg, Ugur Sahin, Konstantine T. Kalogeras, Pirkko-Liisa Kellokumpu-Lehtinen, George Fountzilas, Ralph M. Wirtz, Heikki Joensuu

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells

Hoon Kim, Qun Lin, Peter M. Glazer, Zhong Yun

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

The origins of breast cancer associated with mammographic density: a testable biological hypothesis

Norman Boyd, Hal Berman, Jie Zhu, Lisa J. Martin, Martin J. Yaffe, Sofia Chavez, Greg Stanisz, Greg Hislop, Anna M. Chiarelli, Salomon Minkin, Andrew D. Paterson

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Assessment of performance of the Gail model for predicting breast cancer risk: a systematic review and meta-analysis with trial sequential analysis

Xin Wang, Yubei Huang, Lian Li, Hongji Dai, Fengju Song, Kexin Chen

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Increased circulating resistin levels in early-onset breast cancer patients of normal body mass index correlate with lymph node negative involvement and longer disease free survival: a multi-center POSH cohort serum proteomics study

Bashar Zeidan, Antigoni Manousopoulou, Diana J. Garay-Baquero, Cory H. White, Samantha E. T. Larkin, Kathleen N. Potter, Theodoros I. Roumeliotis, Evangelia K. Papachristou, Ellen Copson, Ramsey I. Cutress, Stephen A. Beers, Diana Eccles, Paul A. Townsend, Spiros D. Garbis

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Murine breast cancer feed arteries are thin-walled with reduced α1A-adrenoceptor expression and attenuated sympathetic vasocontraction

Anne Sofie Froelunde, Marit Ohlenbusch, Kristoffer B. Hansen, Nicolai Jessen, Sukhan Kim, Ebbe Boedtkjer

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours

Rokaya El Ansari, Madeleine L. Craze, Islam Miligy, Maria Diez-Rodriguez, Christopher C. Nolan, Ian O. Ellis, Emad A. Rakha, Andrew R. Green

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer

Yew Chung Tang, Szu-Chi Ho, Elisabeth Tan, Alvin Wei Tian Ng, John R. McPherson, Germaine Yen Lin Goh, Bin Tean Teh, Frederic Bard, Steven G. Rozen

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

The association of mammographic density with risk of contralateral breast cancer and change in density with treatment in the WECARE study

Julia A. Knight, Kristina M. Blackmore, Jing Fan, Kathleen E. Malone, Esther M. John, Charles F. Lynch, Celine M. Vachon, Leslie Bernstein, Jennifer D. Brooks, Anne S. Reiner, Xiaolin Liang, Meghan Woods, Jonine L. Bernstein, WECARE Study Collaborative Group

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

A novel neuregulin – jagged1 paracrine loop in breast cancer transendothelial migration

Ramon M. Cabrera, Serena P. H. Mao, Chinmay R. Surve, John S. Condeelis, Jeffrey E. Segall

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Isocitrate dehydrogenase 1–snail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell invasion ability

Wen-Shan Liu, Shih-Hsuan Chan, Hong-Tai Chang, Guan-Cheng Li, Ya-Ting Tu, Hui-Hwa Tseng, Ting-Ying Fu, Hui-Yu Chang, Huei-Han Liou, Luo-Ping Ger, Kuo-Wang Tsai

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Practice patterns and outcomes for patients with node-negative hormone receptor-positive breast cancer and intermediate 21-gene Recurrence Scores

Jonathan Chen, Xian Wu, Paul J. Christos, Silvia Formenti, Himanshu Nagar

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Effect of neoadjuvant chemotherapy regimen on relapse-free survival among patients with breast cancer achieving a pathologic complete response: an early step in the de-escalation of neoadjuvant chemotherapy

Anna Weiss, Sami I. Bashour, Kenneth Hess, Alastair M. Thompson, Nuhad K. Ibrahim

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Morphology and genomic hallmarks of breast tumours developed by ATM deleterious variant carriers

Anne-Laure Renault, Noura Mebirouk, Laetitia Fuhrmann, Guillaume Bataillon, Eve Cavaciuti, Dorothée Le Gal, Elodie Girard, Tatiana Popova, Philippe La Rosa, Juana Beauvallet, Séverine Eon-Marchais, Marie-Gabrielle Dondon, Catherine Dubois d’Enghien, Anthony Laugé, Walid Chemlali, Virginie Raynal, Martine Labbé, Ivan Bièche, Sylvain Baulande, Jacques-Olivier Bay, Pascaline Berthet, Olivier Caron, Bruno Buecher, Laurence Faivre, Marc Fresnay, Marion Gauthier-Villars, Paul Gesta, Nicolas Janin, Sophie Lejeune, Christine Maugard, Sébastien Moutton, Laurence Venat-Bouvet, Hélène Zattara, Jean-Pierre Fricker, Laurence Gladieff, Isabelle Coupier, Georgia Chenevix-Trench, Janet Hall, Anne Vincent-Salomon, Dominique Stoppa-Lyonnet, Nadine Andrieu, Fabienne Lesueur, CoF-AT, GENESIS, kConFab

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Mitochondrial DNA copy number variation, leukocyte telomere length, and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Daniele Campa, Myrto Barrdahl, Aurelia Santoro, Gianluca Severi, Laura Baglietto, Hanane Omichessan, Rosario Tumino, H. B(as). Bueno-de-Mesquita, Petra H. Peeters, Elisabete Weiderpass, Maria-Dolores Chirlaque, Miguel Rodríguez-Barranco, Antonio Agudo, Marc Gunter, Laure Dossus, Vittorio Krogh, Giuseppe Matullo, Antonia Trichopoulou, Ruth C. Travis, Federico Canzian, Rudolf Kaaks

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Common genetic variation and novel loci associated with volumetric mammographic density

Judith S. Brand, Keith Humphreys, Jingmei Li, Robert Karlsson, Per Hall, Kamila Czene

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Long-term prognostic implications of risk factors associated with tumor size: a case study of women regularly attending screening

Fredrik Strand, Keith Humphreys, Johanna Holm, Mikael Eriksson, Sven Törnberg, Per Hall, Edward Azavedo, Kamila Czene

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

IMP1 regulates UCA1-mediated cell invasion through facilitating UCA1 decay and decreasing the sponge effect of UCA1 for miR-122-5p

Yanchun Zhou, Xiuhua Meng, Shaoying Chen, Wei Li, Delin Li, Robert Singer, Wei Gu

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

Comparison of methods to assess onset of breast development in the LEGACY Girls Study: methodological considerations for studies of breast cancer

Lauren C. Houghton, Julia A. Knight, Mary Jane De Souza, Mandy Goldberg, Melissa L. White, Karen O’Toole, Wendy K. Chung, Angela R. Bradbury, Mary B. Daly, Irene L. Andrulis, Esther M. John, Saundra S. Buys, Mary Beth Terry

01.12.2018 | Research Article | Ausgabe 1/2018 Open Access

MRI-based response patterns during neoadjuvant chemotherapy can predict pathological (complete) response in patients with breast cancer

Briete Goorts, Kelly M. A. Dreuning, Janneke B. Houwers, Loes F. S. Kooreman, Evert-Jan G. Boerma, Ritse M. Mann, Marc B. I. Lobbes, Marjolein L. Smidt

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis

Maria B. Padua, Poornima Bhat-Nakshatri, Manjushree Anjanappa, Mayuri S. Prasad, Yangyang Hao, Xi Rao, Sheng Liu, Jun Wan, Yunlong Liu, Kyle McElyea, Max Jacobsen, George Sandusky, Sandra Althouse, Susan Perkins, Harikrishna Nakshatri

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

The combined effect of mammographic texture and density on breast cancer risk: a cohort study

Johanna O. P. Wanders, Carla H. van Gils, Nico Karssemeijer, Katharina Holland, Michiel Kallenberg, Petra H. M. Peeters, Mads Nielsen, Martin Lillholm

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Real-world evidence analysis of palbociclib prescribing patterns for patients with advanced/metastatic breast cancer treated in community oncology practice in the USA one year post approval

J. K. Kish, M. A. Ward, D. Garofalo, H. V. Ahmed, L. McRoy, J. Laney, G. Zanotti, J. Braverman, H. Yu, B. A. Feinberg

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: a brain magnetic resonance imaging pilot study

Bihong T. Chen, Sean K. Sethi, Taihao Jin, Sunita K. Patel, Ningrong Ye, Can-Lan Sun, Russell C. Rockne, E. Mark Haacke, James C. Root, Andrew J. Saykin, Tim A. Ahles, Andrei I. Holodny, Neal Prakash, Joanne Mortimer, James Waisman, Yuan Yuan, George Somlo, Daneng Li, Richard Yang, Heidi Tan, Vani Katheria, Rachel Morrison, Arti Hurria

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Atypical ductal hyperplasia: update on diagnosis, management, and molecular landscape

Tanjina Kader, Prue Hill, Emad A. Rakha, Ian G. Campbell, Kylie L. Gorringe

01.12.2018 | Short report | Ausgabe 1/2018 Open Access

Circulating ESR1 mutations at the end of aromatase inhibitor adjuvant treatment and after relapse in breast cancer patients

Violette Allouchery, Ludivine Beaussire, Anne Perdrix, David Sefrioui, Laetitia Augusto, Cécile Guillemet, Nasrin Sarafan-Vasseur, Frédéric Di Fiore, Florian Clatot

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasis

Yan Zuo, Arzu Ulu, Jeffrey T. Chang, Jeffrey A. Frost

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions

A. N. Johnston, W. Bu, S. Hein, S. Garcia, L. Camacho, L. Xue, L. Qin, C. Nagi, S. G. Hilsenbeck, J. Kapali, K. Podsypanina, J. Nangia, Y. Li

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Proteolytic single hinge cleavage of pertuzumab impairs its Fc effector function and antitumor activity in vitro and in vivo

Hao-Ching Hsiao, Xuejun Fan, Robert E. Jordan, Ningyan Zhang, Zhiqiang An

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer

Ricardo Ribas, Sunil Pancholi, Aradhana Rani, Eugene Schuster, Stephanie K. Guest, Joanna Nikitorowicz-Buniak, Nikiana Simigdala, Allan Thornhill, Francesca Avogadri-Connors, Richard E. Cutler Jr, Alshad S. Lalani, Mitch Dowsett, Stephen R. Johnston, Lesley-Ann Martin

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women

Jeannette T. Bensen, Mariaelisa Graff, Kristin L. Young, Praveen Sethupathy, Joel Parker, Chad V. Pecot, Kevin Currin, Stephen A. Haddad, Edward A. Ruiz-Narváez, Christopher A. Haiman, Chi-Chen Hong, Lara E. Sucheston-Campbell, Qianqian Zhu, Song Liu, Song Yao, Elisa V. Bandera, Lynn Rosenberg, Kathryn L. Lunetta, Christine B. Ambrosone, Julie R. Palmer, Melissa A. Troester, Andrew F. Olshan

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Quantitative background parenchymal uptake on molecular breast imaging and breast cancer risk: a case-control study

Carrie B. Hruska, Jennifer R. Geske, Tiffinee N. Swanson, Alyssa N. Mammel, David S. Lake, Armando Manduca, Amy Lynn Conners, Dana H. Whaley, Christopher G. Scott, Rickey E. Carter, Deborah J. Rhodes, Michael K. O’Connor, Celine M. Vachon

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Identification of novel human RANK isoforms generated through alternative splicing. Implications in breast cancer cell survival and migration

Anastasios D. Papanastasiou, Chaido Sirinian, Haralabos P. Kalofonos

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Longitudinal enumeration and cluster evaluation of circulating tumor cells improve prognostication for patients with newly diagnosed metastatic breast cancer in a prospective observational trial

Anna-Maria Larsson, Sara Jansson, Pär-Ola Bendahl, Charlotte Levin Tykjaer Jörgensen, Niklas Loman, Cecilia Graffman, Lotta Lundgren, Kristina Aaltonen, Lisa Rydén

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Exploring the prediction performance for breast cancer risk based on volumetric mammographic density at different thresholds

Chao Wang, Adam R. Brentnall, Jack Cuzick, Elaine F. Harkness, D. Gareth Evans, Susan Astley

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

Erin D. Giles, Sonali Jindal, Elizabeth A. Wellberg, Troy Schedin, Steven M. Anderson, Ann D. Thor, Dean P. Edwards, Paul S. MacLean, Pepper Schedin

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Amide chemical exchange saturation transfer at 7 T: a possible biomarker for detecting early response to neoadjuvant chemotherapy in breast cancer patients

Erwin Krikken, Vitaliy Khlebnikov, Moritz Zaiss, Rajni A. Jibodh, Paul J. van Diest, Peter R. Luijten, Dennis W. J. Klomp, Hanneke W. M. van Laarhoven, Jannie P. Wijnen

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Generation of HER2-specific antibody immunity during trastuzumab adjuvant therapy associates with reduced relapse in resected HER2 breast cancer

Nadine Norton, Nicholas Fox, Christie-Ann McCarl, Kathleen S. Tenner, Karla Ballman, Courtney L. Erskine, Brian M. Necela, Donald Northfelt, Winston W. Tan, Carmen Calfa, Mark Pegram, Gerardo Colon-Otero, Edith A. Perez, Raphael Clynes, Keith L. Knutson

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung

Ken Tawara, Celeste Bolin, Jordan Koncinsky, Sujatha Kadaba, Hunter Covert, Caleb Sutherland, Laura Bond, Joseph Kronz, Joel R. Garbow, Cheryl L. Jorcyk

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

Kideok Jin, Niranjan B. Pandey, Aleksander S. Popel

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

NDRG1 regulates neutral lipid metabolism in breast cancer cells

Christopher J. Sevinsky, Faiza Khan, Leila Kokabee, Anza Darehshouri, Krishna Rao Maddipati, Douglas S. Conklin

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Identifying an early treatment window for predicting breast cancer response to neoadjuvant chemotherapy using immunohistopathology and hemoglobin parameters

Quing Zhu, Susan Tannenbaum, Scott H. Kurtzman, Patricia DeFusco, Andrew Ricci Jr, Hamed Vavadi, Feifei Zhou, Chen Xu, Alex Merkulov, Poornima Hegde, Mark Kane, Liqun Wang, Kert Sabbath

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis

Joan S. Lewis-Wambi, Helen R. Kim, Chris Wambi, Roshani Patel, Jennifer R. Pyle, Andres J. Klein-Szanto, V. Craig Jordan

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Can diffusion-weighted imaging predict tumor grade and expression of Ki-67 in breast cancer? A multicenter analysis

Alexey Surov, Paola Clauser, Yun-Woo Chang, Lihua Li, Laura Martincich, Savannah C. Partridge, Jin You Kim, Hans Jonas Meyer, Andreas Wienke

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages

Sara Donzelli, Elisa Milano, Magdalena Pruszko, Andrea Sacconi, Silvia Masciarelli, Ilaria Iosue, Elisa Melucci, Enzo Gallo, Irene Terrenato, Marcella Mottolese, Maciej Zylicz, Alicja Zylicz, Francesco Fazi, Giovanni Blandino, Giulia Fontemaggi

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer

Carla L. Alves, Daniel Elias, Maria B. Lyng, Martin Bak, Henrik J. Ditzel

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Nongenomic oestrogen signalling in oestrogen receptor negative breast cancer cells: a role for the angiotensin II receptor AT1

Kheng Tian Lim, Niamh Cosgrave, Arnold David Hill, Leonie S. Young

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Immune characterization of breast cancer metastases: prognostic implications

Maria Vittoria Dieci, Vassilena Tsvetkova, Enrico Orvieto, Federico Piacentini, Guido Ficarra, Gaia Griguolo, Federica Miglietta, Tommaso Giarratano, Claudia Omarini, Serena Bonaguro, Rocco Cappellesso, Camillo Aliberti, Grazia Vernaci, Carlo Alberto Giorgi, Giovanni Faggioni, Giulia Tasca, Pierfranco Conte, Valentina Guarneri

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer

Xin-Zhong Chang, Da-Qiang Li, Yi-Feng Hou, Jiong Wu, Jin-Song Lu, Gen-Hong Di, Wei Jin, Zhou-Luo Ou, Zhen-Zhou Shen, Zhi-Ming Shao

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Identification and validation of single-sample breast cancer radiosensitivity gene expression predictors

Martin Sjöström, Johan Staaf, Patrik Edén, Fredrik Wärnberg, Jonas Bergh, Per Malmström, Mårten Fernö, Emma Niméus, Irma Fredriksson

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis

Arantzazu Zubeldia-Plazaola, Leire Recalde-Percaz, Núria Moragas, Mireia Alcaraz, Xieng Chen, Mario Mancino, Patricia Fernández-Nogueira, Miquel Prats de Puig, Flavia Guzman, Aleix Noguera-Castells, Anna López-Plana, Estel Enreig, Neus Carbó, Vanessa Almendro, Pedro Gascón, Paloma Bragado, Gemma Fuster

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases

Colleen Chute, Xinhai Yang, Kristy Meyer, Ning Yang, Keelin O’Neil, Ildiko Kasza, Kevin Eliceiri, Caroline Alexander, Andreas Friedl

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Evaluation of α-tubulin, detyrosinated α-tubulin, and vimentin in CTCs: identification of the interaction between CTCs and blood cells through cytoskeletal elements

G. Kallergi, D. Aggouraki, N. Zacharopoulou, C. Stournaras, V. Georgoulias, S. S. Martin

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: The mTOR inhibitor rapamycin down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells

Ma’anit Shapira, Eli Kakiashvili, Tzur Rosenberg, Dan D. Hershko

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Intra-operative spectroscopic assessment of surgical margins during breast conserving surgery

Dustin W. Shipp, Emad A. Rakha, Alexey A. Koloydenko, R. Douglas Macmillan, Ian O. Ellis, Ioan Notingher

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Vitamin D, DNA methylation, and breast cancer

Katie M. O’Brien, Dale P. Sandler, Zongli Xu, H. Karimi Kinyamu, Jack A. Taylor, Clarice R. Weinberg

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers

Michael T. Barrett, Elizabeth Lenkiewicz, Smriti Malasi, Anamika Basu, Jennifer Holmes Yearley, Lakshmanan Annamalai, Ann E. McCullough, Heidi E. Kosiorek, Pooja Narang, Melissa A. Wilson Sayres, Meixuan Chen, Karen S. Anderson, Barbara A. Pockaj

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Circulating microRNAs in the early prediction of disease recurrence in primary breast cancer

Chara Papadaki, Michalis Stratigos, Georgios Markakis, Maria Spiliotaki, Georgios Mastrostamatis, Christoforos Nikolaou, Dimitrios Mavroudis, Sofia Agelaki

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Mandy Dumortier, Franck Ladam, Isabelle Damour, Sophie Vacher, Ivan Bièche, Nathalie Marchand, Yvan de Launoit, David Tulasne, Anne Chotteau-Lelièvre

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation and progression

Chuying Wang, Feng Bai, Li-han Zhang, Alexandria Scott, Enxiao Li, Xin-Hai Pei

01.12.2018 | Short report | Ausgabe 1/2018 Open Access

Intrinsic molecular subtypes of breast cancers categorized as HER2-positive using an alternative chromosome 17 probe assay

Neelam V. Desai, Vanda Torous, Joel Parker, James T. Auman, Gary B. Rosson, Cassandra Cruz, Charles M. Perou, Stuart J. Schnitt, Nadine Tung

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer

Aparna Shinde, Tomasz Wilmanski, Hao Chen, Dorothy Teegarden, Michael K. Wendt

01.12.2018 | Retraction Note | Ausgabe 1/2018 Open Access

Retraction Note: Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis

Jun-Tang Li, Li-Feng Wang, Ya-Li Zhao, Tao Yang, Wei Li, Jing Zhao, Feng Yu, Lei Wang, Yan-Ling Meng, Ning-Ning Liu, Xiao-Shan Zhu, Chun-Fang Gao, Lin-Tao Jia, An-Gang Yang

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Intracellular hypoxia measured by 18F-fluoromisonidazole positron emission tomography has prognostic impact in patients with estrogen receptor-positive breast cancer

Aya Asano, Shigeto Ueda, Ichiei Kuji, Tomohiko Yamane, Hideki Takeuchi, Eiko Hirokawa, Ikuko Sugitani, Hiroko Shimada, Takahiro Hasebe, Akihiko Osaki, Toshiaki Saeki

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer

Maj-Britt Jensen, Anne-Vibeke Lænkholm, Torsten O. Nielsen, Jens Ole Eriksen, Pernille Wehn, Tressa Hood, Namratha Ram, Wesley Buckingham, Sean Ferree, Bent Ejlertsen

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Association of invasion-promoting tenascin-C additional domains with breast cancers in young women

David S. Guttery, Rachael A. Hancox, Kellie T. Mulligan, Simon Hughes, Sinead M. Lambe, J. Howard Pringle, Rosemary A. Walker, J. Louise Jones, Jacqueline A. Shaw

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Effect of exercise and/or reduced calorie dietary interventions on breast cancer-related endogenous sex hormones in healthy postmenopausal women

Martijn de Roon, Anne M. May, Anne McTiernan, Rob J. P. M. Scholten, Petra H. M. Peeters, Christine M. Friedenreich, Evelyn M. Monninkhof

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer

Jennifer R. Diamond, S. G. Eckhardt, Todd M. Pitts, Adrie van Bokhoven, Dara Aisner, Daniel L. Gustafson, Anna Capasso, Sharon Sams, Peter Kabos, Kathryn Zolman, Tiffany Colvin, Anthony D. Elias, Anna M. Storniolo, Bryan P. Schneider, Dexiang Gao, John J. Tentler, Virginia F. Borges, Kathy D. Miller

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Tricho-rhino-phalangeal syndrome 1 protein functions as a scaffold required for ubiquitin-specific protease 4-directed histone deacetylase 2 de-ubiquitination and tumor growth

Yuzhi Wang, Jun Zhang, Lele Wu, Weiguang Liu, Guanyun Wei, Xue Gong, Yan Liu, Zhifang Ma, Fei Ma, Jean Paul Thiery, Liming Chen

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

The added value of mammography in different age-groups of women with and without BRCA mutation screened with breast MRI

Suzan Vreemann, Jan C. M. van Zelst, Margrethe Schlooz-Vries, Peter Bult, Nicoline Hoogerbrugge, Nico Karssemeijer, Albert Gubern-Mérida, Ritse M. Mann

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Can novel technologies improve breast conserving surgery?

Brian W. Pogue

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Nitric oxide deficiency and endothelial–mesenchymal transition of pulmonary endothelium in the progression of 4T1 metastatic breast cancer in mice

Marta Smeda, Anna Kieronska, Mateusz G. Adamski, Bartosz Proniewski, Magdalena Sternak, Tasnim Mohaissen, Kamil Przyborowski, Katarzyna Derszniak, Dawid Kaczor, Marta Stojak, Elzbieta Buczek, Agnieszka Jasztal, Joanna Wietrzyk, Stefan Chlopicki

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Breast cancer patients suggestive of Li-Fraumeni syndrome: mutational spectrum, candidate genes, and unexplained heredity

Judith Penkert, Gunnar Schmidt, Winfried Hofmann, Stephanie Schubert, Maximilian Schieck, Bernd Auber, Tim Ripperger, Karl Hackmann, Marc Sturm, Holger Prokisch, Ursula Hille-Betz, Dorothea Mark, Thomas Illig, Brigitte Schlegelberger, Doris Steinemann

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer

Xu Liang, Sophie Vacher, Anais Boulai, Virginie Bernard, Sylvain Baulande, Mylene Bohec, Ivan Bièche, Florence Lerebours, Céline Callens

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in luminal B breast cancer

Benjamin A. Katchman, I. Tolgay Ocal, Heather E. Cunliffe, Yu-Hui Chang, Galen Hostetter, Aprill Watanabe, Janine LoBello, Douglas F. Lake

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers

Takuya Osada, Zachary C. Hartman, Junping Wei, Gangjun Lei, Amy C. Hobeika, William R. Gwin, Marcio A. Diniz, Neil Spector, Timothy M. Clay, Wei Chen, Michael A. Morse, H. Kim Lyerly

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Breast fibroadenomas are not associated with increased breast cancer risk in an African American contemporary cohort of women with benign breast disease

Asra N. Shaik, Julie J. Ruterbusch, Eman Abdulfatah, Resha Shrestha, M. H. D. Fayez Daaboul, Visakha Pardeshi, Daniel W. Visscher, Sudeshna Bandyopadhyay, Rouba Ali-Fehmi, Michele L. Cote

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

High mammographic density in women is associated with protumor inflammation

Cecilia W. Huo, Prue Hill, Grace Chew, Paul J. Neeson, Heloise Halse, Elizabeth D. Williams, Michael A. Henderson, Erik W. Thompson, Kara L. Britt

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Long-term exposure to insulin and volumetric mammographic density: observational and genetic associations in the Karma study

Signe Borgquist, Ann H. Rosendahl, Kamila Czene, Nirmala Bhoo-Pathy, Mozhgan Dorkhan, Per Hall, Judith S. Brand

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Thyroid hormones and breast cancer association according to menopausal status and body mass index

Carolina Ortega-Olvera, Alfredo Ulloa-Aguirre, Angélica Ángeles-Llerenas, Fernando Enrique Mainero-Ratchelous, Claudia Elena González-Acevedo, Ma. de Lourdes Hernández-Blanco, Elad Ziv, Larissa Avilés-Santa, Edelmiro Pérez-Rodríguez, Gabriela Torres-Mejía

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Volumetric breast density and risk of advanced cancers after a negative screening episode: a cohort study

Donella Puliti, Marco Zappa, Paolo Giorgi Rossi, Elena Pierpaoli, Gianfranco Manneschi, Daniela Ambrogetti, Leonardo Ventura, Paola Mantellini, the DENSITY Working Group

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Clonal relatedness in tumour pairs of breast cancer patients

Jana Biermann, Toshima Z. Parris, Szilárd Nemes, Anna Danielsson, Hanna Engqvist, Elisabeth Werner Rönnerman, Eva Forssell-Aronsson, Anikó Kovács, Per Karlsson, Khalil Helou

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

TNFAIP3 is required for FGFR1 activation-promoted proliferation and tumorigenesis of premalignant DCIS.COM human mammary epithelial cells

Mao Yang, Xiaobin Yu, Xuesen Li, Bo Luo, Wenli Yang, Yan Lin, Dabing Li, Zhonglin Gan, Jianming Xu, Tao He

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Heregulin β1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells

Iain R. Hutcheson, Janice M. Knowlden, Steve E. Hiscox, Denise Barrow, Julia M. W. Gee, John F. Robertson, Ian O. Ellis, Robert I. Nicholson

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Paternal malnutrition programs breast cancer risk and tumor metabolism in offspring

Raquel Santana da Cruz, Elissa J. Carney, Johan Clarke, Hong Cao, M. Idalia Cruz, Carlos Benitez, Lu Jin, Yi Fu, Zuolin Cheng, Yue Wang, Sonia de Assis

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Epigenomics of mammary gland development

Holly Holliday, Laura A. Baker, Simon R. Junankar, Susan J. Clark, Alexander Swarbrick

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Magnetic resonance imaging and molecular features associated with tumor-infiltrating lymphocytes in breast cancer

Jia Wu, Xuejie Li, Xiaodong Teng, Daniel L. Rubin, Sandy Napel, Bruce L. Daniel, Ruijiang Li

01.12.2018 | Meeting report | Ausgabe 1/2018 Open Access

European Network of Breast Development and Cancer turned 10 years: a growing family of mammary gland researchers

Zuzana Koledova, Beatrice A. Howard, Johanna Englund, Karsten Bach, Mohammed Bentires-Alj, Eva Gonzalez-Suarez

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Novel 18-gene signature for predicting relapse in ER-positive, HER2-negative breast cancer

Richard Buus, Belinda Yeo, Adam R. Brentnall, Marie Klintman, Maggie Chon U. Cheang, Komel Khabra, Ivana Sestak, Qiong Gao, Jack Cuzick, Mitch Dowsett

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Obesity promotes the expansion of metastasis-initiating cells in breast cancer

Mélanie Bousquenaud, Flavia Fico, Giovanni Solinas, Curzio Rüegg, Albert Santamaria-Martínez

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

NOTCH3 expression is linked to breast cancer seeding and distant metastasis

Alexey A. Leontovich, Mohammad Jalalirad, Jeffrey L. Salisbury, Lisa Mills, Candace Haddox, Mark Schroeder, Ann Tuma, Maria E. Guicciardi, Luca Zammataro, Mario W. Gambino, Angela Amato, Aldo Di Leonardo, James McCubrey, Carol A. Lange, Minetta Liu, Tufia Haddad, Matthew Goetz, Judy Boughey, Jann Sarkaria, Liewei Wang, James N. Ingle, Evanthia Galanis, Antonino B. D’Assoro

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer

Tian Du, Matthew J. Sikora, Kevin M. Levine, Nilgun Tasdemir, Rebecca B. Riggins, Stacy G. Wendell, Bennett Van Houten, Steffi Oesterreich

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Intracellular hypoxia measured by F-18 fluoromisonidazole positron emission tomography has prognostic impact in patients with estrogen-receptor positive breast (BRCR-D17-00693)

Aya Asano, Shigeto Ueda, Ichiei Kuji, Tomohiko Yamane, Hideki Takeuchi, Eiko Hirokawa, Ikuko Sugitani, Hiroko Shimada, Takahiro Hasebe, Akihiko Osaki, Toshiaki Saeki

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Evaluation of anti-PD-1-based therapy against triple-negative breast cancer patient-derived xenograft tumors engrafted in humanized mouse models

Roberto R. Rosato, Daniel Dávila-González, Dong Soon Choi, Wei Qian, Wen Chen, Anthony J. Kozielski, Helen Wong, Bhuvanesh Dave, Jenny C. Chang

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer

Patrick Schöffski, Sara Cresta, Ingrid A. Mayer, Hans Wildiers, Silvia Damian, Steven Gendreau, Isabelle Rooney, Kari M. Morrissey, Jill M. Spoerke, Vivian W. Ng, Stina M. Singel, Eric Winer

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Maternal breast cancer risk in relation to birthweight and gestation of her offspring

Anthony J. Swerdlow, Lauren B. Wright, Minouk J. Schoemaker, Michael E. Jones

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Mucosal associated invariant T cells from human breast ducts mediate a Th17-skewed response to bacterially exposed breast carcinoma cells

Nicholas A. Zumwalde, Jill D. Haag, Michael N. Gould, Jenny E. Gumperz

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells

Pin Gao, Xiang Wang, Ying Jin, Wenquan Hu, Yajun Duan, Aiping Shi, Ye Du, Dong Song, Ming Yang, Sijie Li, Bing Han, Gang Zhao, Hongquan Zhang, Zhimin Fan, Qing Robert Miao

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Efficient and tumor-specific knockdown of MTDH gene attenuates paclitaxel resistance of breast cancer cells both in vivo and in vitro

Liu Yang, Yanhua Tian, Wei Sun Leong, Heng Song, Wei Yang, Meiqi Wang, Xinle Wang, Jing Kong, Baoen Shan, Zhengchuan Song

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Breast cancer risk factors, survival and recurrence, and tumor molecular subtype: analysis of 3012 women from an indigenous Asian population

Mustapha Abubakar, Hyuna Sung, Devi BCR, Jennifer Guida, Tieng Swee Tang, Ruth M. Pfeiffer, Xiaohong R. Yang

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment

Nathan A. Ungerleider, Sonia G. Rao, Ashkan Shahbandi, Douglas Yee, Tianhua Niu, Wesley D. Frey, James G. Jackson

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance

Hui Zhang, Tricia Fredericks, Gaofeng Xiong, Yifei Qi, Piotr G. Rychahou, Jia-Da Li, Taina Pihlajaniemi, Wei Xu, Ren Xu

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

BHLHE40 confers a pro-survival and pro-metastatic phenotype to breast cancer cells by modulating HBEGF secretion

Aarti Sethuraman, Martin Brown, Raya Krutilina, Zhao-Hui Wu, Tiffany N. Seagroves, Lawrence M. Pfeffer, Meiyun Fan

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Foxf2 plays a dual role during transforming growth factor beta-induced epithelial to mesenchymal transition by promoting apoptosis yet enabling cell junction dissolution and migration

Nathalie Meyer-Schaller, Chantal Heck, Stefanie Tiede, Mahmut Yilmaz, Gerhard Christofori

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Long-term exposure to road traffic noise and incidence of breast cancer: a cohort study

Zorana Jovanovic Andersen, Jeanette Therming Jørgensen, Lea Elsborg, Søren Nymand Lophaven, Claus Backalarz, Jens Elgaard Laursen, Torben Holm Pedersen, Mette Kildevæld Simonsen, Elvira Vaclavik Bräuner, Elsebeth Lynge

01.12.2018 | Short report | Ausgabe 1/2018 Open Access

NR2F1 stratifies dormant disseminated tumor cells in breast cancer patients

Elin Borgen, Maria C. Rypdal, Maria Soledad Sosa, Anne Renolen, Ellen Schlichting, Per E. Lønning, Marit Synnestvedt, Julio A. Aguirre-Ghiso, Bjørn Naume

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Serially transplantable mammary epithelial cells express the Thy-1 antigen

Neethan Amit Lobo, Maider Zabala, Dalong Qian, Michael F. Clarke

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Consistent and reproducible cultures of large-scale 3D mammary epithelial structures using an accessible bioprinting platform

John A. Reid, Peter A. Mollica, Robert D. Bruno, Patrick C. Sachs

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Ribociclib for the first-line treatment of advanced hormone receptor-positive breast cancer: a review of subgroup analyses from the MONALEESA-2 trial

Gabriel N. Hortobagyi

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Aerobic and resistance exercise improves physical fitness, bone health, and quality of life in overweight and obese breast cancer survivors: a randomized controlled trial

Christina M Dieli-Conwright, Kerry S Courneya, Wendy Demark-Wahnefried, Nathalie Sami, Kyuwan Lee, Frank C Sweeney, Christina Stewart, Thomas A Buchanan, Darcy Spicer, Debu Tripathy, Leslie Bernstein, Joanne E Mortimer

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Disrupted circadian clocks and altered tissue mechanics in primary human breast tumours

Eleanor Broadberry, James McConnell, Jack Williams, Nan Yang, Egor Zindy, Angela Leek, Rachel Waddington, Leena Joseph, Miles Howe, Qing-Jun Meng, Charles H Streuli

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Tumor-derived granulocyte colony-stimulating factor diminishes efficacy of breast tumor cell vaccines

Sruthi Ravindranathan, Khue G. Nguyen, Samantha L. Kurtz, Haven N. Frazier, Sean G. Smith, Bhanu prasanth Koppolu, Narasimhan Rajaram, David A. Zaharoff

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

Xuxiang Liu, Minghui Cao, Melanie Palomares, Xiwei Wu, Arthur Li, Wei Yan, Miranda Y. Fong, Wing-Chung Chan, Shizhen Emily Wang

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Integrin-Rac signalling for mammary epithelial stem cell self-renewal

Safiah Olabi, Ahmet Ucar, Keith Brennan, Charles H. Streuli

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Monitoring Src status after dasatinib treatment in HER2+ breast cancer with 89Zr-trastuzumab PET imaging

Brooke N. McKnight, Nerissa T. Viola-Villegas

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth

Serena P. H. Mao, Minji Park, Ramon M. Cabrera, John R. Christin, George S. Karagiannis, Maja H. Oktay, Dietmar M. W. Zaiss, Scott I. Abrams, Wenjun Guo, John S. Condeelis, Paraic A. Kenny, Jeffrey E. Segall

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Age-specific breast cancer risk by body mass index and familial risk: prospective family study cohort (ProF-SC)

John L. Hopper, Gillian S. Dite, Robert J. MacInnis, Yuyan Liao, Nur Zeinomar, Julia A. Knight, Melissa C. Southey, Roger L. Milne, Wendy K. Chung, Graham G. Giles, Jeanine M. Genkinger, Sue-Anne McLachlan, Michael L. Friedlander, Antonis C. Antoniou, Prue C. Weideman, Gord Glendon, Stephanie Nesci, Irene L. Andrulis, Saundra S. Buys, Mary B. Daly, Esther M. John, Kelly Anne Phillips, Mary Beth Terry, kConFab Investigators

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Sulfatide decreases the resistance to stress-induced apoptosis and increases P-selectin-mediated adhesion: a two-edged sword in breast cancer progression

Jaroslaw Suchanski, Jedrzej Grzegrzolka, Tomasz Owczarek, Pawel Pasikowski, Aleksandra Piotrowska, Bartlomiej Kocbach, Aleksandra Nowak, Piotr Dziegiel, Andrzej Wojnar, Maciej Ugorski

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Evaluation of osteopenia and osteoporosis in younger breast cancer survivors compared with cancer-free women: a prospective cohort study

Cody Ramin, Betty J. May, Richard B. S. Roden, Mikiaila M. Orellana, Brenna C. Hogan, Michelle S. McCullough, Dana Petry, Deborah K. Armstrong, Kala Visvanathan

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Inflammation markers and cognitive performance in breast cancer survivors 20 years after completion of chemotherapy: a cohort study

Kimberly D. van der Willik, Vincent Koppelmans, Michael Hauptmann, Annette Compter, M. Arfan Ikram, Sanne B. Schagen

01.12.2018 | Correction | Ausgabe 1/2018 Open Access

Correction to: Consistent and reproducible cultures of large-scale 3D mammary epithelial structures using an accessible bioprinting platform

John A. Reid, Peter A. Mollica, Robert D. Bruno, Patrick C. Sachs

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell expansion

Sara Rhost, Éamon Hughes, Hannah Harrison, Svanheidur Rafnsdottir, Hanna Jacobsson, Pernilla Gregersson, Ylva Magnusson, Paul Fitzpatrick, Daniel Andersson, Karoline Berger, Anders Ståhlberg, Göran Landberg

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment

Alison E. Obr, Sushil Kumar, Yun-Juan Chang, Joseph J. Bulatowicz, Betsy J. Barnes, Raymond B. Birge, Deborah A. Lazzarino, Emily Gallagher, Derek LeRoith, Teresa L. Wood

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

HER4 expression in estrogen receptor-positive breast cancer is associated with decreased sensitivity to tamoxifen treatment and reduced overall survival of postmenopausal women

Anja Kathrin Wege, Dominik Chittka, Stefan Buchholz, Monika Klinkhammer-Schalke, Simone Diermeier-Daucher, Florian Zeman, Olaf Ortmann, Gero Brockhoff

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings

Astrid O. Leech, Sri HariKrishna Vellanki, Emily J. Rutherford, Aoife Keogh, Hanne Jahns, Lance Hudson, Norma O’Donovan, Siham Sabri, Bassam Abdulkarim, Katherine M. Sheehan, Elaine W. Kay, Leonie S. Young, Arnold D. K. Hill, Yvonne E. Smith, Ann M. Hopkins

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer

Marcus Vetter, Julia Landin, Barbara Maria Szczerba, Francesc Castro-Giner, Sofia Gkountela, Cinzia Donato, Ilona Krol, Ramona Scherrer, Catharina Balmelli, Alexandra Malinovska, Alfred Zippelius, Christian Kurzeder, Viola Heinzelmann-Schwarz, Walter Paul Weber, Christoph Rochlitz, Nicola Aceto

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

No association between low-dose aspirin use and breast cancer outcomes overall: a Swedish population-based study

Gabriella Frisk, Sara Ekberg, Elisabet Lidbrink, Sandra Eloranta, Malin Sund, Irma Fredriksson, Mats Lambe, Karin E. Smedby

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Molecular patterns of cancer colonisation in lymph nodes of breast cancer patients

Gaurav Chatterjee, Trupti Pai, Thomas Hardiman, Kelly Avery-Kiejda, Rodney J. Scott, Jo Spencer, Sarah E. Pinder, Anita Grigoriadis

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Statin drugs to reduce breast cancer recurrence and mortality

Colin H. Beckwitt, Adam Brufsky, Zoltán N. Oltvai, Alan Wells

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer

Vanessa F. Merino, Soonweng Cho, Nguyen Nguyen, Helen Sadik, Athira Narayan, Conover Talbot Jr, Leslie Cope, Xian C. Zhou, Zhe Zhang, Balázs Győrffy, Saraswati Sukumar

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Associations between self-reported diet during treatment and chemotherapy-induced peripheral neuropathy in a cooperative group trial (S0221)

Jennifer M. Mongiovi, Gary R. Zirpoli, Rikki Cannioto, Lara E. Sucheston-Campbell, Dawn L. Hershman, Joseph M. Unger, Halle C. F. Moore, James A. Stewart, Claudine Isaacs, Timothy J. Hobday, Muhammad Salim, Gabriel N. Hortobagyi, Julie R. Gralow, G. Thomas Budd, Kathy S. Albain, Christine B. Ambrosone, Susan E. McCann

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Risk prediction for estrogen receptor-specific breast cancers in two large prospective cohorts

Kuanrong Li, Garnet Anderson, Vivian Viallon, Patrick Arveux, Marina Kvaskoff, Agnès Fournier, Vittorio Krogh, Rosario Tumino, Maria-Jose Sánchez, Eva Ardanaz, María-Dolores Chirlaque, Antonio Agudo, David C. Muller, Todd Smith, Ioanna Tzoulaki, Timothy J. Key, Bas Bueno-de-Mesquita, Antonia Trichopoulou, Christina Bamia, Philippos Orfanos, Rudolf Kaaks, Anika Hüsing, Renée T. Fortner, Anne Zeleniuch-Jacquotte, Malin Sund, Christina C. Dahm, Kim Overvad, Dagfinn Aune, Elisabete Weiderpass, Isabelle Romieu, Elio Riboli, Marc J. Gunter, Laure Dossus, Ross Prentice, Pietro Ferrari

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Alterations in arginine and energy metabolism, structural and signalling lipids in metastatic breast cancer in mice detected in plasma by targeted metabolomics and lipidomics

Kamil Kus, Agnieszka Kij, Agnieszka Zakrzewska, Agnieszka Jasztal, Marta Stojak, Maria Walczak, Stefan Chlopicki

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

CYP2D6 phenotype, tamoxifen, and risk of contralateral breast cancer in the WECARE Study

Jennifer D. Brooks, Elizabeth A. Comen, Anne S. Reiner, Irene Orlow, Siok F. Leong, Xiaolin Liang, Lene Mellemkjær, Julia A. Knight, Charles F. Lynch, Esther M. John, Leslie Bernstein, Meghan Woods, David R. Doody, Kathleen E. Malone, Jonine L. Bernstein, The WECARE Study collaborative group

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer

Anjana Bhardwaj, Harpreet Singh, Celestine Marie Trinidad, Constance T. Albarracin, Kelly K. Hunt, Isabelle Bedrosian

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

ErbB2-driven downregulation of the transcription factor Irf6 in breast epithelial cells is required for their 3D growth

Iman Aftab Khan, Byong Hoon Yoo, Michael McPhee, Olivier Masson, Alexi Surette, Kelly Dakin-Hache, Tallal Younis, Gillian Bethune, Kirill V. Rosen

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Predicting interval and screen-detected breast cancers from mammographic density defined by different brightness thresholds

Tuong L. Nguyen, Ye K. Aung, Shuai Li, Nhut Ho Trinh, Christopher F. Evans, Laura Baglietto, Kavitha Krishnan, Gillian S. Dite, Jennifer Stone, Dallas R. English, Yun-Mi Song, Joohon Sung, Mark A. Jenkins, Melissa C. Southey, Graham G. Giles, John L. Hopper

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Overdiagnosis in the population-based organized breast cancer screening program estimated by a non-homogeneous multi-state model: a cohort study using individual data with long-term follow-up

Wendy Yi-Ying Wu, Sven Törnberg, Klara Miriam Elfström, Xijia Liu, Lennarth Nyström, Håkan Jonsson

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

CD68, CD163, and matrix metalloproteinase 9 (MMP-9) co-localization in breast tumor microenvironment predicts survival differently in ER-positive and -negative cancers

Vasiliki Pelekanou, Franz Villarroel-Espindola, Kurt A. Schalper, Lajos Pusztai, David L. Rimm

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Prospective validation of the NCI Breast Cancer Risk Assessment Tool (Gail Model) on 40,000 Australian women

Carolyn Nickson, Pietro Procopio, Louiza S. Velentzis, Sarah Carr, Lisa Devereux, Gregory Bruce Mann, Paul James, Grant Lee, Cameron Wellard, Ian Campbell

01.12.2018 | Research article | Ausgabe 1/2018 Open Access

Adjusting for BMI in analyses of volumetric mammographic density and breast cancer risk

Sue Hudson, Kirsti Vik Hjerkind, Sarah Vinnicombe, Steve Allen, Cassia Trewin, Giske Ursin, Isabel dos-Santos-Silva, Bianca L. De Stavola

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