Ausgabe 1/2019
Inhalt (150 Artikel)
A method of producing genetically manipulated mouse mammary gland
Hiroaki Tagaya, Kosuke Ishikawa, Yoshito Hosokawa, Shun Kobayashi, Yukino Ueoka, Mayuna Shimada, Yasuko Ohashi, Hirofumi Mikami, Mizuki Yamamoto, Tatsuya Ihara, Kentaro Kumazawa, Kosuke Sugihara, Naoki Goshima, Shinya Watanabe, Kentaro Semba
Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours
Cigdem Selli, Arran K. Turnbull, Dominic A. Pearce, Ang Li, Anu Fernando, Jimi Wills, Lorna Renshaw, Jeremy S. Thomas, J. Michael Dixon, Andrew H. Sims
Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas
Joshua Hoffman, Laura Fejerman, Donglei Hu, Scott Huntsman, Min Li, Esther M. John, Gabriela Torres-Mejia, Larry Kushi, Yuan Chun Ding, Jeffrey Weitzel, Susan L. Neuhausen, Paul Lott, Magdalena Echeverry, Luis Carvajal-Carmona, Esteban Burchard, Celeste Eng, Jirong Long, Wei Zheng, Olufunmilayo Olopade, Dezheng Huo, Christopher Haiman, Elad Ziv
Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain
Magdalena Kijewska, Carmen Viski, Frances Turrell, Amanda Fitzpatrick, Antoinette van Weverwijk, Qiong Gao, Marjan Iravani, Clare M. Isacke
Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells
Chong Gao, Gu Xiao, Alessandra Piersigilli, Jiangtao Gou, Olorunseun Ogunwobi, Jill Bargonetti
Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3β activities
Hye Yeon Choi, Gwang-Mo Yang, Ahmed Abdal Dayem, Subbroto Kumar Saha, Kyeongseok Kim, Youngbum Yoo, Kwonho Hong, Jin-Hoi Kim, Cassian Yee, Kyung-Mi Lee, Ssang-Goo Cho
Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP)
Camille Lehuédé, Xia Li, Stéphanie Dauvillier, Charlotte Vaysse, Camille Franchet, Emily Clement, David Esteve, Mélanie Longué, Léonor Chaltiel, Sophie Le Gonidec, Ikrame Lazar, Aline Geneste, Charles Dumontet, Philippe Valet, Laurence Nieto, Frédérique Fallone, Catherine Muller
Localized mammographic density is associated with interval cancer and large breast cancer: a nested case-control study
Fredrik Strand, Edward Azavedo, Roxanna Hellgren, Keith Humphreys, Mikael Eriksson, John Shepherd, Per Hall, Kamila Czene
Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model
Ketil A. Camilio, Meng-Yu Wang, Brynjar Mauseth, Stein Waagene, Gunnar Kvalheim, Øystein Rekdal, Baldur Sveinbjørnsson, Gunhild M. Mælandsmo
HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer
Edward J. Jarman, Carol Ward, Arran K. Turnbull, Carlos Martinez-Perez, James Meehan, Chrysi Xintaropoulou, Andrew H. Sims, Simon P. Langdon
Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer
Marie-Julie Nokin, Justine Bellier, Florence Durieux, Olivier Peulen, Gilles Rademaker, Maude Gabriel, Christine Monseur, Benoit Charloteaux, Lieven Verbeke, Steven van Laere, Patrick Roncarati, Michael Herfs, Charles Lambert, Jean Scheijen, Casper Schalkwijk, Alain Colige, Jo Caers, Philippe Delvenne, Andrei Turtoi, Vincent Castronovo, Akeila Bellahcène
Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer
Abdi Ghaffari, Victoria Hoskin, Gulisa Turashvili, Sonal Varma, Jeff Mewburn, Graeme Mullins, Peter A. Greer, Friedemann Kiefer, Andrew G. Day, Yolanda Madarnas, Sandip SenGupta, Bruce E. Elliott
p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling
Aurélie Chiche, Amandine Di-Cicco, Laura Sesma-Sanz, Laura Bresson, Pierre de la Grange, Marina A. Glukhova, Marisa M. Faraldo, Marie-Ange Deugnier
Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier
Youdinghuan Chen, Yue Wang, Lucas A. Salas, Todd W. Miller, Kenneth Mark, Jonathan D. Marotti, Arminja N. Kettenbach, Chao Cheng, Brock C. Christensen
Letter to the Editor: A response to Hruska’s case study on molecular breast imaging and the need for true tissue quantification
Richard M. Fleming, Matthew R. Fleming, Tapan K. Chaudhuri, William C. Dooley, Andrew McKusick
Associations between dietary patterns and the risk of breast cancer: a systematic review and meta-analysis of observational studies
Yunjun Xiao, Junjie Xia, Liping Li, Yuebin Ke, Jinquan Cheng, Yaojie Xie, Winnie Chu, Polly Cheung, Jean Hee Kim, Graham A. Colditz, Rulla M. Tamimi, Xuefen Su
Serum erythropoietin levels, breast cancer and breast cancer-initiating cells
Kruttika Bhat, Kiri Sandler, Sara Duhachek-Muggy, Claudia Alli, Fei Cheng, Neda A. Moatamed, Clara E. Magyar, Lin Du, Gang Li, Susan McCloskey, Erina Vlashi, Frank Pajonk
A subgroup of microRNAs defines PTEN-deficient, triple-negative breast cancer patients with poorest prognosis and alterations in RB1, MYC, and Wnt signaling
Dong-Yu Wang, Deena M. A. Gendoo, Yaacov Ben-David, James R. Woodgett, Eldad Zacksenhaus
Radiologic complete response (rCR) in contrast-enhanced magnetic resonance imaging (CE-MRI) after neoadjuvant chemotherapy for early breast cancer predicts recurrence-free survival but not pathologic complete response (pCR)
Simon Peter Gampenrieder, Andreas Peer, Christian Weismann, Matthias Meissnitzer, Gabriel Rinnerthaler, Johanna Webhofer, Theresa Westphal, Marina Riedmann, Thomas Meissnitzer, Heike Egger, Frederike Klaassen Federspiel, Roland Reitsamer, Cornelia Hauser-Kronberger, Katharina Stering, Klaus Hergan, Brigitte Mlineritsch, Richard Greil
MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors
Daniela Schwarzenbacher, Christiane Klec, Barbara Pasculli, Stefanie Cerk, Beate Rinner, Michael Karbiener, Cristina Ivan, Raffaela Barbano, Hui Ling, Annika Wulf-Goldenberg, Stefanie Stanzer, Gabriel Rinnerthaler, Herbert Stoeger, Thomas Bauernhofer, Johannes Haybaeck, Gerald Hoefler, Stephan Wenzel Jahn, Paola Parrella, George Adrian Calin, Martin Pichler
Exosomal miRNA profile as complementary tool in the diagnostic and prediction of treatment response in localized breast cancer under neoadjuvant chemotherapy
Alba Rodríguez-Martínez, Diego de Miguel-Pérez, Francisco Gabriel Ortega, José Luis García-Puche, Inmaculada Robles-Fernández, José Exposito, Jordi Martorell-Marugan, Pedro Carmona-Sáez, María del Carmen Garrido-Navas, Christian Rolfo, Hugh Ilyine, José Antonio Lorente, Marta Legueren, María José Serrano
Targeted mutation detection in breast cancer using MammaSeq™
Nicholas G. Smith, Rekha Gyanchandani, Osama S. Shah, Grzegorz T. Gurda, Peter C. Lucas, Ryan J. Hartmaier, Adam M. Brufsky, Shannon Puhalla, Amir Bahreini, Karthik Kota, Abigail I. Wald, Yuri E. Nikiforov, Marina N. Nikiforova, Steffi Oesterreich, Adrian V. Lee
CXCL17-derived CD11b+Gr-1+ myeloid-derived suppressor cells contribute to lung metastasis of breast cancer through platelet-derived growth factor-BB
Ya-Ling Hsu, Meng-Chi Yen, Wei-An Chang, Pei-Hsun Tsai, Yi-Chung Pan, Ssu-Hui Liao, Po-Lin Kuo
Airborne metals and polycyclic aromatic hydrocarbons in relation to mammographic breast density
Alexandra J. White, Clarice R. Weinberg, Ellen S. O’Meara, Dale P. Sandler, Brian L. Sprague
Imprint of parity and age at first pregnancy on the genomic landscape of subsequent breast cancer
Bastien Nguyen, David Venet, Matteo Lambertini, Christine Desmedt, Roberto Salgado, Hugo Mark Horlings, Françoise Rothé, Christos Sotiriou
Correction to: Targeted therapy against Bcl-2-related proteins in breast cancer cells
Manabu Emi, Ryungsa Kim, Kazuaki Tanabe, Yoko Uchida, Tetsuya Toge
MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer
Yoshimi Endo Greer, Samuel F. Gilbert, Brunilde Gril, Rajesh Narwal, Danielle L. Peacock Brooks, David A. Tice, Patricia S. Steeg, Stanley Lipkowitz
Infiltrating stromal immune cells in inflammatory breast cancer are associated with an improved outcome and increased PD-L1 expression
C. Van Berckelaer, C. Rypens, P. van Dam, L. Pouillon, M. Parizel, K. A. Schats, M. Kockx, W. A. A. Tjalma, P. Vermeulen, S. van Laere, F. Bertucci, C. Colpaert, L. Dirix
AMP-activated protein kinase: a potential therapeutic target for triple-negative breast cancer
Wei Cao, Jieqing Li, Qiongyu Hao, Jaydutt V Vadgama, Yong Wu
Prognostic and predictive value of androgen receptor expression in postmenopausal women with estrogen receptor-positive breast cancer: results from the Breast International Group Trial 1–98
Kevin H. Kensler, Meredith M. Regan, Yujing J. Heng, Gabrielle M. Baker, Michael E. Pyle, Stuart J. Schnitt, Aditi Hazra, Roswitha Kammler, Beat Thürlimann, Marco Colleoni, Giuseppe Viale, Myles Brown, Rulla M. Tamimi
Osteoblasts are “educated” by crosstalk with metastatic breast cancer cells in the bone tumor microenvironment
Alexus D. Kolb, Alison B. Shupp, Dimpi Mukhopadhyay, Frank C. Marini, Karen M. Bussard
Patterns of occurrence and implications of neratinib-associated diarrhea in patients with HER2-positive breast cancer: analyses from the randomized phase III ExteNET trial
Joanne Mortimer, Jack Di Palma, Kendra Schmid, Yining Ye, Mohammad Jahanzeb
The distribution and determinants of mammographic density measures in Western Australian aboriginal women
Kirsty McLean, Ellie Darcey, Gemma Cadby, Helen Lund, Leanne Pilkington, Andrew Redfern, Sandra Thompson, Christobel Saunders, Elizabeth Wylie, Jennifer Stone
The long-term prognostic and predictive capacity of cyclin D1 gene amplification in 2305 breast tumours
Arian Lundberg, Linda S. Lindström, Jingmei Li, J. Chuck Harrell, Eva Darai-Ramqvist, Emmanouil G. Sifakis, Theodoros Foukakis, Charles M. Perou, Kamila Czene, Jonas Bergh, Nicholas P. Tobin
Updating the role of obesity and cholesterol in breast cancer
Laura Garcia-Estevez, Gema Moreno-Bueno
Separation of breast cancer and organ microenvironment transcriptomes in metastases
Mohammad A. Alzubi, Tia H. Turner, Amy L. Olex, Sahib S. Sohal, Nicholas P. Tobin, Susana G. Recio, Jonas Bergh, Thomas Hatschek, Joel S. Parker, Carol A. Sartorius, Charles M. Perou, Mikhail G. Dozmorov, J. Chuck Harrell
GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer
Geraldine Vidhya Vijay, Na Zhao, Petra Den Hollander, Mike J. Toneff, Robiya Joseph, Mika Pietila, Joseph H. Taube, Tapasree R. Sarkar, Esmeralda Ramirez-Pena, Steven J. Werden, Maryam Shariati, Ruli Gao, Mary Sobieski, Clifford C. Stephan, Nathalie Sphyris, Noayuki Miura, Peter Davies, Jeffrey T. Chang, Rama Soundararajan, Jeffrey M. Rosen, Sendurai A. Mani
Impact of short-term low-dose tamoxifen on molecular breast imaging background parenchymal uptake: a pilot study
Carrie B. Hruska, Katie N. Hunt, Amy Lynn Conners, Jennifer R. Geske, Kathleen R. Brandt, Amy C. Degnim, Celine M. Vachon, Michael K. O’Connor, Deborah J. Rhodes
PIK3CA alterations and benefit with neratinib: analysis from the randomized, double-blind, placebo-controlled, phase III ExteNET trial
Stephen K. L. Chia, Miguel Martin, Frankie A. Holmes, Bent Ejlertsen, Suzette Delaloge, Beverly Moy, Hiroji Iwata, Gunter von Minckwitz, Janine Mansi, Carlos H. Barrios, Michael Gnant, Zorica Tomašević, Neelima Denduluri, Robert Šeparović, Sung-Bae Kim, Erik Hugger Jakobsen, Vernon Harvey, Nicholas Robert, John Smith II, Graydon Harker, Bo Zhang, Lisa D. Eli, Yining Ye, Alshad S. Lalani, Marc Buyse, Arlene Chan
Parity, breastfeeding, and breast cancer risk by hormone receptor status and molecular phenotype: results from the Nurses’ Health Studies
Renée T. Fortner, Julia Sisti, Boyang Chai, Laura C. Collins, Bernard Rosner, Susan E. Hankinson, Rulla M. Tamimi, A. Heather Eliassen
Impact of obesity on breast cancer recurrence and minimal residual disease
Brett L. Ecker, Jun Y. Lee, Christopher J. Sterner, Aaron C. Solomon, Dhruv K. Pant, Fei Shen, Javier Peraza, Lauren Vaught, Samyukta Mahendra, George K. Belka, Tien-chi Pan, Kathryn H. Schmitz, Lewis A. Chodosh
Breast cancer risk prediction in women aged 35–50 years: impact of including sex hormone concentrations in the Gail model
Tess V. Clendenen, Wenzhen Ge, Karen L. Koenig, Yelena Afanasyeva, Claudia Agnoli, Louise A. Brinton, Farbod Darvishian, Joanne F. Dorgan, A. Heather Eliassen, Roni T. Falk, Göran Hallmans, Susan E. Hankinson, Judith Hoffman-Bolton, Timothy J. Key, Vittorio Krogh, Hazel B. Nichols, Dale P. Sandler, Minouk J. Schoemaker, Patrick M. Sluss, Malin Sund, Anthony J. Swerdlow, Kala Visvanathan, Anne Zeleniuch-Jacquotte, Mengling Liu
Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer
Sean P. Kennedy, Jeremy Z. R. Han, Neil Portman, Max Nobis, Jordan F. Hastings, Kendelle J. Murphy, Sharissa L. Latham, Antonia L. Cadell, Dushan Miladinovic, Gabriella R. Marriott, Yolande E. I. O’Donnell, Robert F. Shearer, James T. Williams, Amaya Garcia Munoz, Thomas R. Cox, D. Neil Watkins, Darren N. Saunders, Paul Timpson, Elgene Lim, Walter Kolch, David R. Croucher
Hypothyroidism and the risk of breast cancer recurrence and all-cause mortality - a Danish population-based study
Anne Mette Falstie-Jensen, Anders Kjærsgaard, Ebbe Laugaard Lorenzen, Jeanette Dupont Jensen, Kristin Valborg Reinertsen, Olaf M. Dekkers, Marianne Ewertz, Deirdre P. Cronin-Fenton
Correction to: ECM1 regulates cell proliferation and trastuzumab resistance through activation of EGF-signaling
Kyung-min Lee, Keesoo Nam, Sunhwa Oh, Juyeon Lim, Young-Pil Kim, Jong Won Lee, Jong-Han Yu, Sei-Hyun Ahn, Sung-Bae Kim, Dong-Young Noh, Taehoon Lee, Incheol Shin
Genomic signature of parity in the breast of premenopausal women
Julia Santucci-Pereira, Anne Zeleniuch-Jacquotte, Yelena Afanasyeva, Hua Zhong, Michael Slifker, Suraj Peri, Eric A. Ross, Ricardo López de Cicco, Yubo Zhai, Theresa Nguyen, Fathima Sheriff, Irma H. Russo, Yanrong Su, Alan A. Arslan, Pal Bordas, Per Lenner, Janet Åhman, Anna Stina Landström Eriksson, Robert Johansson, Göran Hallmans, Paolo Toniolo, Jose Russo
The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1
Junmei Cairns, James N. Ingle, Krishna R. Kalari, Lois E. Shepherd, Michiaki Kubo, Matthew P. Goetz, Richard M. Weinshilboum, Liewei Wang
Body mass index, mammographic density, and breast cancer risk by estrogen receptor subtype
Yiwey Shieh, Christopher G. Scott, Matthew R. Jensen, Aaron D. Norman, Kimberly A. Bertrand, V. Shane Pankratz, Kathleen R. Brandt, Daniel W. Visscher, John A. Shepherd, Rulla M. Tamimi, Celine M. Vachon, Karla Kerlikowske
CD68, CD163, and matrix metalloproteinase 9 (MMP-9) in breast tumor microenvironment to predict breast cancer survival: are they enough?
Sara Bravaccini, Roberta Maltoni
Association between prediagnostic leukocyte telomere length and breast cancer risk: the Singapore Chinese Health Study
Hamed Samavat, Xiaoshuang Xun, Aizhen Jin, Renwei Wang, Woon-Puay Koh, Jian-Min Yuan
BRCA1 mutations attenuate super-enhancer function and chromatin looping in haploinsufficient human breast epithelial cells
Xiaowen Zhang, Yao Wang, Huai-Chin Chiang, Yuan-Pang Hsieh, Chang Lu, Ben Ho Park, Ismail Jatoi, Victor X. Jin, Yanfen Hu, Rong Li
Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study
Rebecca D. Kehm, John L. Hopper, Esther M. John, Kelly-Anne Phillips, Robert J. MacInnis, Gillian S. Dite, Roger L. Milne, Yuyan Liao, Nur Zeinomar, Julia A. Knight, Melissa C. Southey, Linda Vahdat, Naomi Kornhauser, Tessa Cigler, Wendy K. Chung, Graham G. Giles, Sue-Anne McLachlan, Michael L. Friedlander, Prue C. Weideman, Gord Glendon, Stephanie Nesci, Irene L. Andrulis, Saundra S. Buys, Mary B. Daly, Mary Beth Terry
The pro- and anti-tumor roles of mesenchymal stem cells toward BRCA1-IRIS-overexpressing TNBC cells
Daniel Ryan, Bibbin T. Paul, Jim Koziol, Wael M. ElShamy
The opposing effects of interferon-beta and oncostatin-M as regulators of cancer stem cell plasticity in triple-negative breast cancer
Mary R. Doherty, Jenny G. Parvani, Ilaria Tamagno, Damian J. Junk, Benjamin L. Bryson, Hyeon Joo Cheon, George R. Stark, Mark W. Jackson
Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer
Nana Weber-Lassalle, Julika Borde, Konstantin Weber-Lassalle, Judit Horváth, Dieter Niederacher, Norbert Arnold, Silke Kaulfuß, Corinna Ernst, Victoria G. Paul, Ellen Honisch, Kristina Klaschik, Alexander E. Volk, Christian Kubisch, Steffen Rapp, Nadine Lichey, Janine Altmüller, Louisa Lepkes, Esther Pohl-Rescigno, Holger Thiele, Peter Nürnberg, Mirjam Larsen, Lisa Richters, Kerstin Rhiem, Barbara Wappenschmidt, Christoph Engel, Alfons Meindl, Rita K. Schmutzler, Eric Hahnen, Jan Hauke
Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2
Elizabeth Slocum, Amanda Craig, Augusto Villanueva, Doris Germain
Distant metastasis dynamics following subsequent surgeries after primary breast cancer removal
Romano Demicheli, Hanna Dillekås, Oddbjørn Straume, Elia Biganzoli
Frequency of pathogenic germline variants in BRCA1, BRCA2, PALB2, CHEK2 and TP53 in ductal carcinoma in situ diagnosed in women under the age of 50 years
Christos Petridis, Iteeka Arora, Vandna Shah, Anargyros Megalios, Charlotte Moss, Anca Mera, Angela Clifford, Cheryl Gillett, Sarah E. Pinder, Ian Tomlinson, Rebecca Roylance, Michael A. Simpson, Elinor J. Sawyer
Deciphering the role of interferon alpha signaling and microenvironment crosstalk in inflammatory breast cancer
Olivia K. Provance, Joan Lewis-Wambi
Development of central nervous system metastases as a first site of metastatic disease in breast cancer patients treated in the neoadjuvant trials GeparQuinto and GeparSixto
Elena Laakmann, Isabell Witzel, Peter A. Fasching, Mahdi Rezai, Christian Schem, Christine Solbach, Hans Tesch, Peter Klare, Andreas Schneeweiss, Christoph Salat, Dirk-Michael Zahm, Jens-Uwe Blohmer, Barbara Ingold-Heppner, Jens Huober, Claus Hanusch, Christian Jackisch, Mattea Reinisch, Michael Untch, Gunter von Minckwitz, Valentina Nekljudova, Volkmar Müller, Sibylle Loibl
Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer
Maria T. Grinde, Bylgja Hilmarsdottir, Hanna Maja Tunset, Ida Marie Henriksen, Jana Kim, Mads H. Haugen, Morten Beck Rye, Gunhild M. Mælandsmo, Siver A. Moestue
Blood DNA methylation and breast cancer risk: a meta-analysis of four prospective cohort studies
Clara Bodelon, Srikant Ambatipudi, Pierre-Antoine Dugué, Annelie Johansson, Joshua N. Sampson, Belynda Hicks, Eric Karlins, Amy Hutchinson, Cyrille Cuenin, Veronique Chajès, Melissa C. Southey, Isabelle Romieu, Graham G. Giles, Dallas English, Silvia Polidoro, Manuela Assumma, Laura Baglietto, Paolo Vineis, Gianluca Severi, Zdenko Herceg, James M. Flanagan, Roger L. Milne, Montserrat Garcia-Closas
Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo
Veronika Ramovs, Pablo Secades, Ji-Ying Song, Bram Thijssen, Maaike Kreft, Arnoud Sonnenberg
Nicotinamide N-methyltransferase enhances chemoresistance in breast cancer through SIRT1 protein stabilization
Yanzhong Wang, Jin Zeng, Weiping Wu, Shuduo Xie, Haitao Yu, Guoli Li, Tao Zhu, Fengying Li, Jie Lu, Gavin Y. Wang, Xinyou Xie, Jun Zhang
Identification of three subtypes of triple-negative breast cancer with potential therapeutic implications
Pascal Jézéquel, Olivier Kerdraon, Hubert Hondermarck, Catherine Guérin-Charbonnel, Hamza Lasla, Wilfried Gouraud, Jean-Luc Canon, Andrea Gombos, Florence Dalenc, Suzette Delaloge, Jérôme Lemonnier, Delphine Loussouarn, Véronique Verrièle, Mario Campone
Rack1 mediates tyrosine phosphorylation of Anxa2 by Src and promotes invasion and metastasis in drug-resistant breast cancer cells
Yanling Fan, Weiyao Si, Wei Ji, Zhiyong Wang, Zicong Gao, Ran Tian, Weijie Song, He Zhang, Ruifang Niu, Fei Zhang
Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models
Rachel A. Sabol, Annie C. Bowles, Alex Côté, Rachel Wise, Benjamen O’Donnell, Margarite D. Matossian, Fokhrul M. Hossain, Hope E. Burks, Luis Del Valle, Lucio Miele, Bridgette M. Collins-Burow, Matthew E. Burow, Bruce A. Bunnell
Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk
Celine M. Vachon, Christopher G. Scott, Rulla M. Tamimi, Deborah J. Thompson, Peter A. Fasching, Jennifer Stone, Melissa C. Southey, Stacey Winham, Sara Lindström, Jenna Lilyquist, Graham G. Giles, Roger L. Milne, Robert J. MacInnis, Laura Baglietto, Jingmei Li, Kamila Czene, Manjeet K. Bolla, Qin Wang, Joe Dennis, Lothar Haeberle, Mikael Eriksson, Peter Kraft, Robert Luben, Nick Wareham, Janet E. Olson, Aaron Norman, Eric C. Polley, Gertraud Maskarinec, Loic Le Marchand, Christopher A. Haiman, John L. Hopper, Fergus J. Couch, Douglas F. Easton, Per Hall, Nilanjan Chatterjee, Montse Garcia-Closas
Nintedanib plus letrozole in early breast cancer: a phase 0/I pharmacodynamic, pharmacokinetic, and safety clinical trial of combined FGFR1 and aromatase inhibition
Miguel Quintela-Fandino, Juan V. Apala, Diego Malon, Silvana Mouron, Javier Hornedo, Lucia Gonzalez-Cortijo, Ramon Colomer, Juan Guerra
Association between C-reactive protein and radiotherapy-related pain in a tri-racial/ethnic population of breast cancer patients: a prospective cohort study
Eunkyung Lee, Omar L. Nelson, Carolina Puyana, Cristiane Takita, Jean L. Wright, Wei Zhao, Isildinha M. Reis, Rick Y. Lin, WayWay M. Hlaing, Johnna L. Bakalar, George R. Yang, Jennifer J. Hu
Clinical outcomes after palbociclib with or without endocrine therapy in postmenopausal women with hormone receptor positive and HER2-negative metastatic breast cancer enrolled in the TREnd trial
Lorenzo Rossi, Chiara Biagioni, Amelia McCartney, Ilenia Migliaccio, Giuseppe Curigliano, Giuseppina Sanna, Erica Moretti, Alessandro M. Minisini, Saverio Cinieri, Carlo Tondini, Grazia Arpino, Antonio Bernardo, Angelo Martignetti, Emanuela Risi, Marta Pestrin, Luca Boni, Matteo Benelli, Laura Biganzoli, Angelo Di Leo, Luca Malorni
Reanalysis of the NCCN PD-L1 companion diagnostic assay study for lung cancer in the context of PD-L1 expression findings in triple-negative breast cancer
David L. Rimm, Gang Han, Janis M. Taube, Eunhee S. Yi, Julia A. Bridge, Douglas B. Flieder, Robert Homer, Anja C. Roden, Fred R. Hirsch, Ignacio I. Wistuba, Lajos Pusztai
On-treatment biomarkers can improve prediction of response to neoadjuvant chemotherapy in breast cancer
Richard J. Bownes, Arran K. Turnbull, Carlos Martinez-Perez, David A. Cameron, Andrew H. Sims, Olga Oikonomidou
The p52 isoform of SHC1 is a key driver of breast cancer initiation
Kevin D. Wright, Bradley S. Miller, Sarah El-Meanawy, Shirng-Wern Tsaih, Anjishnu Banerjee, Aron M. Geurts, Yuri Sheinin, Yunguang Sun, Balaraman Kalyanaraman, Hallgeir Rui, Michael J. Flister, Andrey Sorokin
Machine learning techniques for personalized breast cancer risk prediction: comparison with the BCRAT and BOADICEA models
Chang Ming, Valeria Viassolo, Nicole Probst-Hensch, Pierre O. Chappuis, Ivo D. Dinov, Maria C. Katapodi
Gene expression signature of atypical breast hyperplasia and regulation by SFRP1
Kelly J. Gregory, Amy L. Roberts, Erin M. Conlon, Jacob A. Mayfield, Mary J. Hagen, Giovanna M. Crisi, Brooke A. Bentley, Jeffrey J. Kane, Grace Makari-Judson, Holly S. Mason, Jun Yu, Lihua Julie Zhu, Karl Simin, Jacob P. S. Johnson, Ashraf Khan, Ben R. Schneider, Sallie S. Schneider, D. Joseph Jerry
A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy
Ronan P. McLaughlin, Jichao He, Vera E. van der Noord, Jevin Redel, John A. Foekens, John W. M. Martens, Marcel Smid, Yinghui Zhang, Bob van de Water
Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation
Yan Xing, Nancy U. Lin, Matthew A. Maurer, Huiqin Chen, Armeen Mahvash, Aysegul Sahin, Argun Akcakanat, Yisheng Li, Vandana Abramson, Jennifer Litton, Mariana Chavez-MacGregor, Vicente Valero, Sarina A. Piha-Paul, David Hong, Kim-Anh Do, Emily Tarco, Dianna Riall, Agda Karina Eterovic, Gerburg M. Wulf, Lewis C. Cantley, Gordon B. Mills, L. Austin Doyle, Eric Winer, Gabriel N. Hortobagyi, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam
Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer
Sònia Palomeras, Ángel Diaz-Lagares, Gemma Viñas, Fernando Setien, Humberto J. Ferreira, Glòria Oliveras, Ana B. Crujeiras, Alejandro Hernández, David H. Lum, Alana L. Welm, Manel Esteller, Teresa Puig
Abrupt involution induces inflammation, estrogenic signaling, and hyperplasia linking lack of breastfeeding with increased risk of breast cancer
Mustafa M. Basree, Neelam Shinde, Christopher Koivisto, Maria Cuitino, Raleigh Kladney, Jianying Zhang, Julie Stephens, Marilly Palettas, Allen Zhang, Hee Kyung Kim, Santiago Acero-Bedoya, Anthony Trimboli, Daniel G. Stover, Thomas Ludwig, Ramesh Ganju, Daniel Weng, Peter Shields, Jo Freudenheim, Gustavo W. Leone, Gina M. Sizemore, Sarmila Majumder, Bhuvaneswari Ramaswamy
Relationship of circulating insulin-like growth factor-I and binding proteins 1–7 with mammographic density among women undergoing image-guided diagnostic breast biopsy
Manila Hada, Hannah Oh, Ruth M. Pfeiffer, Roni T. Falk, Shaoqi Fan, Maeve Mullooly, Michael Pollak, Berta Geller, Pamela M. Vacek, Donald Weaver, John Shepherd, Jeff Wang, Bo Fan, Amir Pasha Mahmoudzadeh, Serghei Malkov, Sally Herschorn, Louise A. Brinton, Mark E. Sherman, Gretchen L. Gierach
Glucocorticoid receptor modulation decreases ER-positive breast cancer cell proliferation and suppresses wild-type and mutant ER chromatin association
Eva Tonsing-Carter, Kyle M. Hernandez, Caroline R. Kim, Ryan V. Harkless, Alyce Oh, Kathleen R. Bowie, Diana C. West-Szymanski, Mayra A. Betancourt-Ponce, Bradley D. Green, Ricardo R. Lastra, Gini F. Fleming, Sarat Chandarlapaty, Suzanne D. Conzen
A whole slide image-based machine learning approach to predict ductal carcinoma in situ (DCIS) recurrence risk
Sergey Klimov, Islam M. Miligy, Arkadiusz Gertych, Yi Jiang, Michael S. Toss, Padmashree Rida, Ian O. Ellis, Andrew Green, Uma Krishnamurti, Emad A. Rakha, Ritu Aneja
Vitamin D receptor expression in invasive breast tumors and breast cancer survival
Linnea Huss, Salma Tunå Butt, Signe Borgquist, Karin Elebro, Malte Sandsveden, Ann Rosendahl, Jonas Manjer
Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers
Christian Fougner, Helga Bergholtz, Raoul Kuiper, Jens Henrik Norum, Therese Sørlie
The prognostic value of JUNB-positive CTCs in metastatic breast cancer: from bioinformatics to phenotypic characterization
Galatea Kallergi, Vasileia Tsintari, Stelios Sfakianakis, Ekaterini Bei, Eleni Lagoudaki, Anastasios Koutsopoulos, Nefeli Zacharopoulou, Saad Alkahtani, Saud Alarifi, Christos Stournaras, Michalis Zervakis, Vassilis Georgoulias
Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers
Bradley A. Hancock, Yu-Hsiang Chen, Jeffrey P. Solzak, Mufti N. Ahmad, David C. Wedge, Dumitru Brinza, Charles Scafe, James Veitch, Rajesh Gottimukkala, Walt Short, Rutuja V. Atale, Mircea Ivan, Sunil S. Badve, Bryan P. Schneider, Xiongbin Lu, Kathy D. Miller, Milan Radovich
Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer
Ami Hori, Masafumi Shimoda, Yasuto Naoi, Naofumi Kagara, Tomonori Tanei, Tomohiro Miyake, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
Dynamically decreased miR-671-5p expression is associated with oncogenic transformation and radiochemoresistance in breast cancer
Xiaohui Tan, Zhongwu Li, Shuchang Ren, Katayoon Rezaei, Qing Pan, Andrew T. Goldstein, Charles J. Macri, Dengfeng Cao, Rachel F. Brem, Sidney W. Fu
Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes
Marcelo Sobral-Leite, Izhar Salomon, Mark Opdam, Dinja T. Kruger, Karin J. Beelen, Vincent van der Noort, Ronald L. P. van Vlierberghe, Erik J. Blok, Daniele Giardiello, Joyce Sanders, Koen Van de Vijver, Hugo M. Horlings, Peter J. K. Kuppen, Sabine C. Linn, Marjanka K. Schmidt, Marleen Kok
Investigating the feasibility of stratified breast cancer screening using a masking risk predictor
Olivier Alonzo-Proulx, James G. Mainprize, Jennifer A. Harvey, Martin J. Yaffe
Development of a prediction model for breast cancer based on the national cancer registry in Taiwan
Ching-Chieh Huang, Soa-Yu Chan, Wen-Chung Lee, Chun-Ju Chiang, Tzu-Pin Lu, Skye Hung-Chun Cheng
Inequities in breast cancer treatment in sub-Saharan Africa: findings from a prospective multi-country observational study
Milena Foerster, Benjamin O. Anderson, Fiona McKenzie, Moses Galukande, Angelica Anele, Charles Adisa, Annelle Zietsman, Joachim Schuz, Isabel dos Santos Silva, Valerie McCormack
Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2+ve breast cancer metastasis
Aadya Nagpal, Richard P. Redvers, Xiawei Ling, Scott Ayton, Miriam Fuentes, Elnaz Tavancheh, Irmina Diala, Alshad Lalani, Sherene Loi, Steven David, Robin L. Anderson, Yvonne Smith, Delphine Merino, Delphine Denoyer, Normand Pouliot
Disease trajectories and mortality among women diagnosed with breast cancer
Haomin Yang, Yudi Pawitan, Wei He, Louise Eriksson, Natalie Holowko, Per Hall, Kamila Czene
Environmental exposures during windows of susceptibility for breast cancer: a framework for prevention research
Mary Beth Terry, Karin B. Michels, Julia Green Brody, Celia Byrne, Shiuan Chen, D. Joseph Jerry, Kristen M. C. Malecki, Mary Beth Martin, Rachel L. Miller, Susan L. Neuhausen, Kami Silk, Amy Trentham-Dietz, Jasmine McDonald, Sabine Oskar, Julia Knight, Rosario Toro-Campos, Xiaomei Cai, Camella J. Rising, Dasha Afanaseva, Michaela Devyn Mullis, Mary Pat Berry, Jennifer Bird, Christopher Bradfield, Ronald Gangnon, Michael Gould, John Hampton, Sara Lindberg, Sarah Luongo, Kristen Malecki, Betsy Rolland, James Shull, Mia Gaudet, Mark Thornquist, Mark D. Aupperlee, Sandra Z. Haslam, Reyhane Hoshyar, Anastasia Kariagina, Juliana R. Lopes, Karen J. Miller, Olena Morozova, Cathy J. Newkirk, Richard C. Schwartz, Brandon Thomas, Daniel Totzkay, Fang Xie, Kami J. Silk, Frank M. Biro, Cecily S. Fassler, Courtney M. Giannini, Susan Pinney, Melissa A. Troester, Kimberly Burke, Julie Herbstman, Rebecca Kehm, Logthar Lilge, Rachel Miller, Frederica Perera, Debeshish Sahay, Parisa Tehranifar, Mary Beth Terry, Desiree Walker, Nur Zeinomar, Milagros de Hoz, Peggy Shepard, Alexandra Binder, Karin Michels, Vincent Bessonneau, Julia Brody, Vanessa De La Rosa, Jennifer Ohayon, Ruthann Rudel, Camila Corvalan, Ana Pereira, Julia Pereira, Jose Russo, Su Yanrong, John Shepherd, Lucile Adams-Campbell, Chiranjeev Dash, Bassem Haddad, Rhonda Hamilton, Mary Beth Martin, Brenda Richardson, Celia Byrne, Hristina Denic-Roberts, Gregory Chang, Shiuan Chen, Yuan Chun Ding, Noriko Kanaya, Susan Neuhausen, Michele Rakoff, Kohei Saeki, Mayra Serrano, Peggy Reynolds, Karen Dunphy, Joseph Jerry, Anna Symington, Laura Vandenberg, Sallie Schneider, Swann Arp Adams, Heather M. Brandt, Daniela Friedman, Jamie R. Lead, Gary Kreps, Kevin Wright, Amelia Burke-Garcia, Carla Fisher
Addition of zoledronic acid to neoadjuvant chemotherapy is not beneficial in patients with HER2-negative stage II/III breast cancer: 5-year survival analysis of the NEOZOTAC trial (BOOG 2010-01)
Stefanie de Groot, Hanno Pijl, Ayoub Charehbili, Saskia van de Ven, Vincent T. H. B. M. Smit, Elma Meershoek-Klein Kranenbarg, Joan B. Heijns, Laurence J. C. van Warmerdam, Lonneke W. Kessels, M. Wouter Dercksen, Manon J. A. E. Pepels, Hanneke W. M. van Laarhoven, Birgit E. P. J. Vriens, Hein Putter, Marta Fiocco, Gerrit-Jan Liefers, Jacobus J. M. van der Hoeven, Johan W. R. Nortier, Judith R. Kroep
Investigating circulating tumor cells and distant metastases in patient-derived orthotopic xenograft models of triple-negative breast cancer
Vishnu C. Ramani, Clementine A. Lemaire, Melanie Triboulet, Kerriann M. Casey, Kyra Heirich, Corinne Renier, José G. Vilches-Moure, Rakhi Gupta, Aryana M. Razmara, Haiyu Zhang, George W. Sledge, Elodie Sollier, Stefanie S. Jeffrey
Calcium-sensing stromal interaction molecule 2 upregulates nuclear factor of activated T cells 1 and transforming growth factor-β signaling to promote breast cancer metastasis
Yutian Miao, Qiang Shen, Siheng Zhang, Hehai Huang, Xiaojing Meng, Xianchong Zheng, Zhuocheng Yao, Zhanxin He, Sitong Lu, Chunqing Cai, Fei Zou
A randomized, controlled phase II trial of neoadjuvant ado-trastuzumab emtansine, lapatinib, and nab-paclitaxel versus trastuzumab, pertuzumab, and paclitaxel in HER2-positive breast cancer (TEAL study)
Tejal A. Patel, Joe E. Ensor, Sarah L. Creamer, Toniva Boone, Angel A. Rodriguez, Poly A. Niravath, Jorge G. Darcourt, Jane L. Meisel, Xiaoxian Li, Jing Zhao, John G. Kuhn, Roberto R. Rosato, Wei Qian, Anna Belcheva, Mary R. Schwartz, Virginia G. Kaklamani, Jenny C. Chang
Clonality of circulating tumor cells in breast cancer brain metastasis patients
Carlotta Riebensahm, Simon A. Joosse, Malte Mohme, Annkathrin Hanssen, Jakob Matschke, Yvonne Goy, Isabell Witzel, Katrin Lamszus, Jolanthe Kropidlowski, Cordula Petersen, Anja Kolb-Kokocinski, Sascha Sauer, Kerstin Borgmann, Markus Glatzel, Volkmar Müller, Manfred Westphal, Sabine Riethdorf, Klaus Pantel, Harriet Wikman
Diffusion tensor imaging for characterizing tumor microstructure and improving diagnostic performance on breast MRI: a prospective observational study
Jing Luo, Daniel S. Hippe, Habib Rahbar, Sana Parsian, Mara H. Rendi, Savannah C. Partridge
Targeting myeloid-derived suppressor cells in combination with primary mammary tumor resection reduces metastatic growth in the lungs
Momir Bosiljcic, Rachel A. Cederberg, Melisa J. Hamilton, Nancy E. LePard, Bryant T. Harbourne, Jenna L. Collier, Elizabeth C. Halvorsen, Rocky Shi, S. Elizabeth Franks, Ada Y. Kim, Judit P. Banáth, Mark Hamer, Fabio M. Rossi, Kevin L. Bennewith
Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells
Chinnadurai Mani, Shirisha Jonnalagadda, Jojireddy Lingareddy, Sanjay Awasthi, William H. Gmeiner, Komaraiah Palle
A functional role for the cancer disparity-linked genes, CRYβB2 and CRYβB2P1, in the promotion of breast cancer
Maya A. Barrow, Megan E. Martin, Alisha Coffey, Portia L. Andrews, Gieira S. Jones, Denise K. Reaves, Joel S. Parker, Melissa A. Troester, Jodie M. Fleming
Radiomic signatures with contrast-enhanced magnetic resonance imaging for the assessment of breast cancer receptor status and molecular subtypes: initial results
Doris Leithner, Joao V. Horvat, Maria Adele Marino, Blanca Bernard-Davila, Maxine S. Jochelson, R. Elena Ochoa-Albiztegui, Danny F. Martinez, Elizabeth A. Morris, Sunitha Thakur, Katja Pinker
Li-Fraumeni syndrome: not a straightforward diagnosis anymore—the interpretation of pathogenic variants of low allele frequency and the differences between germline PVs, mosaicism, and clonal hematopoiesis
Felipe Batalini, Ellie G. Peacock, Lindsey Stobie, Alison Robertson, Judy Garber, Jeffrey N. Weitzel, Nadine M. Tung
Oral metronomic vinorelbine combined with endocrine therapy in hormone receptor-positive HER2-negative breast cancer: SOLTI-1501 VENTANA window of opportunity trial
Barbara Adamo, Meritxell Bellet, Laia Paré, Tomás Pascual, Maria Vidal, José A. Pérez Fidalgo, Salvador Blanch, Noelia Martinez, Laura Murillo, Patricia Gómez-Pardo, Ana López-González, Kepa Amillano, Jordi Canes, Patricia Galván, Blanca González-Farré, Xavier González, Patricia Villagrasa, Eva Ciruelos, Aleix Prat
Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression
Jiang Ren, Marcel Smid, Josephine Iaria, Daniela C. F. Salvatori, Hans van Dam, Hong Jian Zhu, John W. M. Martens, Peter ten Dijke
Adjuvant chemotherapy and survival among patients 70 years of age and younger with node-negative breast cancer and the 21-gene recurrence score of 26–30
Seho Park, Yunan Han, Ying Liu, Adetunji T. Toriola, Lindsay L. Peterson, Graham A. Colditz, Seung Il Kim, Young Up Cho, Byeong-Woo Park, Yikyung Park
Sensitivity of screening mammography by density and texture: a cohort study from a population-based screening program in Denmark
My von Euler-Chelpin, Martin Lillholm, Ilse Vejborg, Mads Nielsen, Elsebeth Lynge
Tumour heterogeneity revealed by unsupervised decomposition of dynamic contrast-enhanced magnetic resonance imaging is associated with underlying gene expression patterns and poor survival in breast cancer patients
Ming Fan, Pingping Xia, Bin Liu, Lin Zhang, Yue Wang, Xin Gao, Lihua Li
Metastatic behavior and overall survival according to breast cancer subtypes in stage IV inflammatory breast cancer
D. J. P. van Uden, M. C. van Maaren, L. J. A. Strobbe, P. Bult, J. J. van der Hoeven, S. Siesling, J. H. W. de Wilt, C. F. J. M. Blanken-Peeters
Quantitative nuclear histomorphometric features are predictive of Oncotype DX risk categories in ductal carcinoma in situ: preliminary findings
Haojia Li, Jon Whitney, Kaustav Bera, Hannah Gilmore, Mangesh A. Thorat, Sunil Badve, Anant Madabhushi
Metformin overcomes resistance to cisplatin in triple-negative breast cancer (TNBC) cells by targeting RAD51
Jung Ok Lee, Min Ju Kang, Won Seok Byun, Shin Ae Kim, Il Hyeok Seo, Jeong Ah. Han, Ji Wook Moon, Ji Hae Kim, Su Jin Kim, Eun Jung Lee, Serk In Park, Sun Hwa Park, Hyeon Soo Kim
Targeting of prostate-specific membrane antigen for radio-ligand therapy of triple-negative breast cancer
Agnieszka Morgenroth, Ebru Tinkir, Andreas T. J. Vogg, Ramya Ambur Sankaranarayanan, Fatima Baazaoui, Felix M. Mottaghy
Pre- to postdiagnosis leisure-time physical activity and prognosis in postmenopausal breast cancer survivors
Audrey Y. Jung, Sabine Behrens, Martina Schmidt, Kathrin Thoene, Nadia Obi, Anika Hüsing, Axel Benner, Karen Steindorf, Jenny Chang-Claude
Automated volumetric breast density measures: differential change between breasts in women with and without breast cancer
Kathleen R. Brandt, Christopher G. Scott, Diana L. Miglioretti, Matthew R. Jensen, Amir P. Mahmoudzadeh, Carrie Hruska, Lin Ma, Fang Fang Wu, Steven R. Cummings, Aaron D. Norman, Natalie J. Engmann, John A. Shepherd, Stacey J. Winham, Karla Kerlikowske, Celine M. Vachon
Phase I clinical trial of the combination of eribulin and everolimus in patients with metastatic triple-negative breast cancer
Jin Sun Lee, Susan E. Yost, Suzette Blanchard, Daniel Schmolze, Hongwei Holly Yin, Raju Pillai, Kim Robinson, Aileen Tang, Norma Martinez, Jana Portnow, Wei Wen, John H. Yim, Heather Ann Brauer, Yuqi Ren, Thehang Luu, Joanne Mortimer, Yuan Yuan
Associations of race and ethnicity with risk of developing invasive breast cancer after lobular carcinoma in situ
Vanessa Dania, Ying Liu, Foluso Ademuyiwa, Jason D. Weber, Graham A. Colditz
Actionability of HER2-amplified circulating tumor cells in HER2-negative metastatic breast cancer: the CirCe T-DM1 trial
William Jacot, Paul Cottu, Frederique Berger, Coraline Dubot, Laurence Venat-Bouvet, Alain Lortholary, Hugues Bourgeois, Marc Bollet, Veronique Servent, Elisabeth Luporsi, Marc Espié, Severine Guiu, Veronique D’Hondt, Veronique Dieras, Marie-Paule Sablin, Etienne Brain, Souhir Neffati, Jean-Yves Pierga, Francois-Clement Bidard
Pubertal timing and breast density in young women: a prospective cohort study
Lauren C. Houghton, Seungyoun Jung, Rebecca Troisi, Erin S. LeBlanc, Linda G. Snetselaar, Nola M. Hylton, Catherine Klifa, Linda Van Horn, Kenneth Paris, John A. Shepherd, Robert N. Hoover, Joanne F. Dorgan
WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells
Simona Punzi, Chiara Balestrieri, Carolina D’Alesio, Daniela Bossi, Gaetano Ivan Dellino, Elena Gatti, Giancarlo Pruneri, Carmen Criscitiello, Giulia Lovati, Marine Meliksetyan, Alessandro Carugo, Giuseppe Curigliano, Gioacchino Natoli, Pier Giuseppe Pelicci, Luisa Lanfrancone
BRCA1 mutation influences progesterone response in human benign mammary organoids
Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E. Clare, Seema A. Khan, J. Julie Kim
Loss of SIM2s inhibits RAD51 binding and leads to unresolved replication stress
Scott J. Pearson, Jessica Elswood, Rola Barhoumi, Brittini Ming-Whitfield, Monique Rijnkels, Weston W. Porter
High expression of NR1D1 is associated with good prognosis in triple-negative breast cancer patients treated with chemotherapy
Hyelin Na, Jinil Han, Na-Lee Ka, Min-Ho Lee, Yoon-La Choi, Young Kee Shin, Mi-Ock Lee
Alcohol consumption, cigarette smoking, and familial breast cancer risk: findings from the Prospective Family Study Cohort (ProF-SC)
Nur Zeinomar, Julia A. Knight, Jeanine M. Genkinger, Kelly-Anne Phillips, Mary B. Daly, Roger L. Milne, Gillian S. Dite, Rebecca D. Kehm, Yuyan Liao, Melissa C. Southey, Wendy K. Chung, Graham G. Giles, Sue-Anne McLachlan, Michael L. Friedlander, Prue C. Weideman, Gord Glendon, Stephanie Nesci, Irene L. Andrulis, Saundra S. Buys, Esther M. John, Robert J. MacInnis, John L. Hopper, Mary Beth Terry
Ductal tree ablation by local delivery of ethanol prevents tumor formation in an aggressive mouse model of breast cancer
Elizabeth Kenyon, Jennifer J. Westerhuis, Maximilian Volk, Jeremy Hix, Shatadru Chakravarty, Ethan Claucherty, Erin Zaluzec, Lisa Ramsey, Zach Madaj, Galen Hostetter, Bryn Eagleson, Erik Shapiro, Anna Moore, Lorenzo F. Sempere
Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts
Diane Lefley, Faith Howard, Fawaz Arshad, Steven Bradbury, Hannah Brown, Claudia Tulotta, Rachel Eyre, Denis Alférez, J. Mark Wilkinson, Ingunn Holen, Robert B. Clarke, Penelope Ottewell
Cross-talk between SIM2s and NFκB regulates cyclooxygenase 2 expression in breast cancer
Garhett L. Wyatt, Lyndsey S. Crump, Chloe M. Young, Veronica M. Wessells, Cole M. McQueen, Steven W. Wall, Tanya L. Gustafson, Yang-Yi Fan, Robert S. Chapkin, Weston W. Porter, Traci R. Lyons
Combining RANK/RANKL and ERBB-2 targeting as a novel strategy in ERBB-2-positive breast carcinomas
Ilianna Zoi, Michalis V. Karamouzis, Evangelia Xingi, Panagiotis Sarantis, Dimitra Thomaidou, Panayiotis Lembessis, Stamatios Theocharis, Athanasios G. Papavassiliou
NSABP FB-7: a phase II randomized neoadjuvant trial with paclitaxel + trastuzumab and/or neratinib followed by chemotherapy and postoperative trastuzumab in HER2+ breast cancer
Samuel A. Jacobs, André Robidoux, Jame Abraham, José Manuel Pérez-Garcia, Nicla La Verde, James M. Orcutt, Marina E. Cazzaniga, Fanny Piette, Silvia Antolín, Elena Aguirre, Javier Cortes, Antonio Llombart-Cussac, Serena Di Cosimo, Rim S. Kim, Huichen Feng, Corey Lipchik, Peter C. Lucas, Ashok Srinivasan, Ying Wang, Nan Song, Patrick G. Gavin, April D. Balousek, Soonmyung Paik, Carmen J. Allegra, Norman Wolmark, Katherine L. Pogue-Geile
CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer
Yu-Ju Lee, Shiuh-Rong Ho, Joshua D. Graves, Yang Xiao, Shixia Huang, Weei-Chin Lin
Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer
Sunil Pancholi, Mariana Ferreira Leal, Ricardo Ribas, Nikiana Simigdala, Eugene Schuster, Sophie Chateau-Joubert, Lila Zabaglo, Margaret Hills, Andrew Dodson, Qiong Gao, Stephen R. Johnston, Mitch Dowsett, Sabina C. Cosulich, Elisabetta Maragoni, Lesley-Ann Martin
Limited role of DWI with apparent diffusion coefficient mapping in breast lesions presenting as non-mass enhancement on dynamic contrast-enhanced MRI
Daly Avendano, Maria Adele Marino, Doris Leithner, Sunitha Thakur, Blanca Bernard-Davila, Danny F. Martinez, Thomas H. Helbich, Elizabeth A. Morris, Maxine S. Jochelson, Pascal A. T. Baltzer, Paola Clauser, Panagiotis Kapetas, Katja Pinker
Association of a novel circulating tumor DNA next-generating sequencing platform with circulating tumor cells (CTCs) and CTC clusters in metastatic breast cancer
Andrew A. Davis, Qiang Zhang, Lorenzo Gerratana, Ami N. Shah, Youbin Zhan, Wenan Qiang, Brian S. Finkelman, Lisa Flaum, Amir Behdad, William J. Gradishar, Leonidas C. Platanias, Massimo Cristofanilli
Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells
Monica M. Montano, I-Ju Yeh, Yinghua Chen, Chris Hernandez, Janna G. Kiselar, Maria de la Fuente, Adriane M. Lawes, Marvin T. Nieman, Philip D. Kiser, James Jacobberger, Agata A. Exner, Matthew C. Lawes
Psychiatric disorders and cardiovascular diseases during the diagnostic workup of potential breast cancer: a population-based cohort study in Skåne, Sweden
Qing Shen, Anna Jöud, Maria E. C. Schelin, Arvid Sjölander, Yang Cao, Pär Sparén, Katja Fall, Kamila Czene, Unnur Valdimarsdóttir, Fang Fang
The atypical cyclin-like protein Spy1 overrides p53-mediated tumour suppression and promotes susceptibility to breast tumourigenesis
Bre-Anne Fifield, Ingrid Qemo, Evie Kirou, Robert D. Cardiff, Lisa Ann Porter
Characterization of organoid cultured human breast cancer
Nadine Goldhammer, Jiyoung Kim, Vera Timmermans-Wielenga, Ole William Petersen
Human leucocyte antigen class I in hormone receptor-positive, HER2-negative breast cancer: association with response and survival after neoadjuvant chemotherapy
Bruno Valentin Sinn, Karsten E. Weber, Wolfgang Daniel Schmitt, Peter A. Fasching, William Fraser Symmans, Jens-Uwe Blohmer, Thomas Karn, Eliane Tabea Taube, Frederick Klauschen, Frederik Marmé, Christian Schem, Elmar Stickeler, Beyhan Ataseven, Jens Huober, Gunter von Minckwitz, Barbara Seliger, Carsten Denkert, Sibylle Loibl
Current treatment landscape for patients with locally recurrent inoperable or metastatic triple-negative breast cancer: a systematic literature review
Claire H. Li, Vassiliki Karantza, Gursel Aktan, Mallika Lala
Prediction and clinical utility of a contralateral breast cancer risk model
Daniele Giardiello, Ewout W. Steyerberg, Michael Hauptmann, Muriel A. Adank, Delal Akdeniz, Carl Blomqvist, Stig E. Bojesen, Manjeet K. Bolla, Mariël Brinkhuis, Jenny Chang-Claude, Kamila Czene, Peter Devilee, Alison M. Dunning, Douglas F. Easton, Diana M. Eccles, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Montserrat García-Closas, Lothar Haeberle, Christopher A. Haiman, Per Hall, Ute Hamann, John L. Hopper, Agnes Jager, Anna Jakubowska, Audrey Jung, Renske Keeman, Iris Kramer, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Jan Lubiński, Mehdi Manoochehri, Luigi Mariani, Heli Nevanlinna, Hester S. A. Oldenburg, Saskia Pelders, Paul D. P. Pharoah, Mitul Shah, Sabine Siesling, Vincent T. H. B. M. Smit, Melissa C. Southey, William J. Tapper, Rob A. E. M. Tollenaar, Alexandra J. van den Broek, Carolien H. M. van Deurzen, Flora E. van Leeuwen, Chantal van Ongeval, Laura J. Van’t Veer, Qin Wang, Camilla Wendt, Pieter J. Westenend, Maartje J. Hooning, Marjanka K. Schmidt
Neutrophil extracellular traps in breast cancer and beyond: current perspectives on NET stimuli, thrombosis and metastasis, and clinical utility for diagnosis and treatment
Hunter T. Snoderly, Brian A. Boone, Margaret F. Bennewitz
Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors
Hitisha K. Patel, Nianjun Tao, Kyung-Min Lee, Mariela Huerta, Heike Arlt, Tara Mullarkey, Steven Troy, Carlos L. Arteaga, Teeru Bihani
Immune gene expression profiling reveals heterogeneity in luminal breast tumors
Bin Zhu, Lap Ah Tse, Difei Wang, Hela Koka, Tongwu Zhang, Mustapha Abubakar, Priscilla Lee, Feng Wang, Cherry Wu, Koon Ho Tsang, Wing-cheong Chan, Sze Hong Law, Mengjie Li, Wentao Li, Suyang Wu, Zhiguang Liu, Bixia Huang, Han Zhang, Eric Tang, Zhengyan Kan, Soohyeon Lee, Yeon Hee Park, Seok Jin Nam, Mingyi Wang, Xuezheng Sun, Kristine Jones, Bin Zhu, Amy Hutchinson, Belynda Hicks, Ludmila Prokunina-Olsson, Jianxin Shi, Montserrat Garcia-Closas, Stephen Chanock, Xiaohong R. Yang
Plasma cell-free DNA (cfDNA) as a predictive and prognostic marker in patients with metastatic breast cancer
Daniel Fernandez-Garcia, Allison Hills, Karen Page, Robert K. Hastings, Bradley Toghill, Kate S. Goddard, Charlotte Ion, Olivia Ogle, Anna Rita Boydell, Kelly Gleason, Mark Rutherford, Adrian Lim, David S. Guttery, R. Charles Coombes, Jacqueline A. Shaw
Estrogen receptor coregulator binding modulator (ERX-11) enhances the activity of CDK4/6 inhibitors against estrogen receptor-positive breast cancers
Suryavathi Viswanadhapalli, Shihong Ma, Gangadhara Reddy Sareddy, Tae-Kyung Lee, Mengxing Li, Collin Gilbreath, Xihui Liu, Yiliao Luo, Uday P. Pratap, Mei Zhou, Eliot B. Blatt, Kara Kassees, Carlos Arteaga, Prasanna Alluri, Manjeet Rao, Susan T. Weintraub, Rajeshwar Rao Tekmal, Jung-Mo Ahn, Ganesh V. Raj, Ratna K. Vadlamudi
Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer
Iris Nederlof, Davide De Bortoli, Yacine Bareche, Bastien Nguyen, Michiel de Maaker, Gerrit K. J. Hooijer, Laurence Buisseret, Marleen Kok, Marcel Smid, Gert G. G. M. Van den Eynden, Arie B. Brinkman, Jan Hudecek, Jan Koster, Christos Sotiriou, Denis Larsimont, John W. M. Martens, Marc J. van de Vijver, Hugo M. Horlings, Roberto Salgado, Elia Biganzoli, Christine Desmedt
Endocrine-responsive lobular carcinoma of the breast: features associated with risk of late distant recurrence
Fabio Conforti, Laura Pala, Eleonora Pagan, Giuseppe Viale, Vincenzo Bagnardi, Giulia Peruzzotti, Tommaso De Pas, Nadia Bianco, Rossella Graffeo, Elena Guerini Rocco, Andrea Vingiani, Richard D. Gelber, Alan S. Coates, Marco Colleoni, Aron Goldhirsch