Ausgabe 2/2014
Inhalt (32 Artikel)
Trastuzumab emtansine: mechanisms of action and drug resistance
Mark Barok, Heikki Joensuu, Jorma Isola
In silicoanalysis of microRNA-510 as a potential oncomir in human breast cancer
Pawel Gaj, Radoslaw Zagozdzon
Early but not late pregnancy induces lifelong reductions in the proportion of mammary progesterone sensing cells and epithelial Wnt signaling
Fabienne Meier-Abt, Heike Brinkhaus, Mohamed Bentires-Alj
Fibroblast growth factor receptor splice variants are stable markers of oncogenic transforming growth factor β1 signaling in metastatic breast cancers
Michael K Wendt, Molly A Taylor, Barbara J Schiemann, Khalid Sossey-Alaoui, William P Schiemann
Engagement of immune effector cells by trastuzumab induces HER2/ERBB2 downregulation in cancer cells through STAT1 activation
Yun Shi, Xuejun Fan, Weixu Meng, Hui Deng, Ningyan Zhang, Zhiqiang An
Biopsy confirmation of metastatic sites in breast cancer patients: clinical impact and future perspectives
Carmen Criscitiello, Fabrice André, Alastair M Thompson, Michele De Laurentiis, Angela Esposito, Lucia Gelao, Luca Fumagalli, Marzia Locatelli, Ida Minchella, Franco Orsi, Aron Goldhirsch, Giuseppe Curigliano
Sex hormone associations with breast cancer risk and the mediation of randomized trial postmenopausal hormone therapy effects
Shanshan Zhao, Rowan T Chlebowski, Garnet L Anderson, Lewis H Kuller, JoAnn E Manson, Margery Gass, Ruth Patterson, Thomas E Rohan, Dorothy S Lane, Shirley AA Beresford, Sayeh Lavasani, Jacques E Rossouw, Ross L Prentice
Outsmarting cancer: the power of hybrid genomic/proteomic biomarkers to predict drug response
Brent N Rexer, Carlos L Arteaga
N-myc downstream-regulated gene 2 expression is associated with glucose transport and correlated with prognosis in breast carcinoma
Ji Ma, Wenchao Liu, Hang Guo, Shaoqing Li, Wei Cao, Xilin Du, Shixiong Lei, Wugang Hou, Lize Xiong, Libo Yao, Nanlin Li, Yan Li
Malignant phyllodes tumors display mesenchymal stem cell features and aldehyde dehydrogenase/disialoganglioside identify their tumor stem cells
Jin-Jin Lin, Chiun-Sheng Huang, John Yu, Guo-Shiou Liao, Huang-Chun Lien, Jung-Tung Hung, Ruey-Jen Lin, Fen-Pi Chou, Kun-Tu Yeh, Alice L Yu
Phase 2 trial of everolimus and carboplatin combination in patients with triple negative metastatic breast cancer
Jasmeet Chadha Singh, Yelena Novik, Stacey Stein, Matthew Volm, Marlene Meyers, Julia Smith, Coral Omene, James Speyer, Robert Schneider, Komal Jhaveri, Silvia Formenti, Victoria Kyriakou, Benson Joseph, Judith D Goldberg, Xiaochun Li, Sylvia Adams, Amy Tiersten
A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissue
Arvydas Laurinavicius, Benoit Plancoulaine, Aida Laurinaviciene, Paulette Herlin, Raimundas Meskauskas, Indra Baltrusaityte, Justinas Besusparis, Darius Dasevicius, Nicolas Elie, Yasir Iqbal, Catherine Bor, Ian O Ellis
Post-diagnostic prescriptions for low-dose aspirin and breast cancer-specific survival: a nested case-control study in a breast cancer cohort from the UK Clinical Practice Research Datalink
Liam J Murray, Janine A Cooper, Carmel M Hughes, Des G Powe, Chris R Cardwell
Mammographic texture resemblance generalizes as an independent risk factor for breast cancer
Mads Nielsen, Celine M Vachon, Christopher G Scott, Konstantin Chernoff, Gopal Karemore, Nico Karssemeijer, Martin Lillholm, Morten A Karsdal
Effects of an exercise and hypocaloric healthy eating intervention on indices of psychological health status, hypothalamic-pituitary-adrenal axis regulation and immune function after early-stage breast cancer: a randomised controlled trial
John M Saxton, Emma J Scott, Amanda J Daley, M Nicola Woodroofe, Nanette Mutrie, Helen Crank, Hilary J Powers, Robert E Coleman
Maternal exposure to diethylstilbestrol during pregnancy and increased breast cancer risk in daughters
Leena Hilakivi-Clarke
Retinoblastoma tumor suppressor pathway in breast cancer: prognosis, precision medicine, and therapeutic interventions
Agnieszka K Witkiewicz, Erik S Knudsen
Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening
Sireesha V Garimella, Kristie Gehlhaus, Jennifer L Dine, Jason J Pitt, Magdalena Grandin, Sirisha Chakka, Marion M Nau, Natasha J Caplen, Stanley Lipkowitz
New insights into the role of ID proteins in breast cancer metastasis: a MET affair
Wee Siang Teo, Radhika Nair, Alexander Swarbrick
Combining the strength of genomics, nanoparticle technology, and direct intraductal delivery for breast cancer treatment
Wei Wen Teo, Saraswati Sukumar
Smoking at time of diagnosis and breast cancer-specific survival: new findings and systematic review with meta-analysis
Sylvie Bérubé, Julie Lemieux, Lynne Moore, Elizabeth Maunsell, Jacques Brisson
A BRCA1deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity
Ryan P McMullin, Ben S Wittner, Chuanwei Yang, Benjamin R Denton-Schneider, Daniel Hicks, Raj Singavarapu, Sharon Moulis, Jeongeun Lee, Mohammad R Akbari, Steven A Narod, Kenneth D Aldape, Patricia S Steeg, Sridhar Ramaswamy, Dennis C Sgroi
Heterogeneous atypical cell populations are present in blood of metastatic breast cancer patients
Maryam B Lustberg, Priya Balasubramanian, Brandon Miller, Alejandra Garcia-Villa, Clayton Deighan, Yongqi Wu, Sarah Carothers, Michael Berger, Bhuvaneswari Ramaswamy, Erin R Macrae, Robert Wesolowski, Rachel M Layman, Ewa Mrozek, Xueliang Pan, Thomas A Summers, Charles L Shapiro, Jeffrey J Chalmers
Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank
Ivanesa Pardo, Heather A Lillemoe, Rachel J Blosser, MiRan Choi, Candice A M Sauder, Diane K Doxey, Theresa Mathieson, Bradley A Hancock, Dadrie Baptiste, Rutuja Atale, Matthew Hickenbotham, Jin Zhu, Jarret Glasscock, Anna Maria V Storniolo, Faye Zheng, RW Doerge, Yunlong Liu, Sunil Badve, Milan Radovich, Susan E Clare
Receptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways
Stina M Singel, Kimberly Batten, Crystal Cornelius, Gaoxiang Jia, Gail Fasciani, Summer L Barron, Woodring E Wright, Jerry W Shay
Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling
Sonali Jindal, Dexiang Gao, Pat Bell, Grethe Albrektsen, Susan M Edgerton, Christine B Ambrosone, Ann D Thor, Virginia F Borges, Pepper Schedin
Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition
Haiyu Zhang, Adam L Cohen, Sujatha Krishnakumar, Irene L Wapnir, Selvaraju Veeriah, Glenn Deng, Marc A Coram, Caroline M Piskun, Teri A Longacre, Michael Herrler, Daniel O Frimannsson, Melinda L Telli, Frederick M Dirbas, AC Matin, Shanaz H Dairkee, Banafshe Larijani, Gennadi V Glinsky, Andrea H Bild, Stefanie S Jeffrey
Clinical validation of the EndoPredict test in node-positive, chemotherapy-treated ER+/HER2− breast cancer patients: results from the GEICAM 9906 trial
Miguel Martin, Jan C Brase, Lourdes Calvo, Kristin Krappmann, Manuel Ruiz-Borrego, Karin Fisch, Amparo Ruiz, Karsten E Weber, Blanca Munarriz, Christoph Petry, Cesar A Rodriguez, Ralf Kronenwett, Carmen Crespo, Emilio Alba, Eva Carrasco, Maribel Casas, Rosalia Caballero, Alvaro Rodriguez-Lescure
Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2
Sheng Tan, Keshuo Ding, Rui Li, Weijie Zhang, Gaopeng Li, Xiangjun Kong, Pengxu Qian, Peter E Lobie, Tao Zhu
International study on inter-reader variability for circulating tumor cells in breast cancer
Michail Ignatiadis, Sabine Riethdorf, François-Clement Bidard, Isabelle Vaucher, Mustapha Khazour, Françoise Rothé, Jessica Metallo, Ghizlane Rouas, Rachel E Payne, Raoul Charles Coombes, Ingrid Teufel, Ulrich Andergassen, Stella Apostolaki, Eleni Politaki, Dimitris Mavroudis, Silvia Bessi, Marta Pestrin, Angelo Di Leo, Michael Campion, Monica Reinholz, Edith Perez, Martine Piccart, Elin Borgen, Bjorn Naume, Jose Jimenez, Claudia Monica Aura, Laura Zorzino, Maria Cristina Cassatella, Maria Teresa Sandri, Bianca Mostert, Stefan Sleijfer, Jaco Kraan, Wolfgang Janni, Tanja Fehm, Brigitte Rack, Leon Terstappen, Madeline Repollet, Jean-Yves Pierga, Craig Miller, Christos Sotiriou, Stefan Michiels, Klaus Pantel
Status of adjuvant endocrine therapy for breast cancer
Gaia Schiavon, Ian E Smith
Changes in aldehyde dehydrogenase-1 expression during neoadjuvant chemotherapy predict outcome in locally advanced breast cancer
Muhammad Alamgeer, Vinod Ganju, Beena Kumar, Jane Fox, Stewart Hart, Michelle White, Marion Harris, John Stuckey, Zdenka Prodanovic, Michal Elisabeth Schneider-Kolsky, D Neil Watkins