Ausgabe 4/2012
Inhalt (36 Artikel)
Battle over CCL2 for control of the metastatic niche: neutrophils versus monocytes
Jonathan B Mitchem, David G DeNardo
ER and PR signaling nodes during mammary gland development
Tamara Tanos, Lucia Jimenez Rojo, Pablo Echeverria, Cathrin Brisken
New methods in mammary gland development and cancer: proteomics, epigenetics, symmetric division and metastasis
Mohamed Bentires-Alj, Marina Glukhova, Nancy Hynes, Maria dM Vivanco
Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk
Lauren A Matise, Trenis D Palmer, William J Ashby, Abudi Nashabi, Anna Chytil, Mary Aakre, Michael W Pickup, Agnieszka E Gorska, Andries Zijlstra, Harold L Moses
Promoter hypermethylation in male breast cancer: analysis by multiplex ligation-dependent probe amplification
Robert Kornegoor, Cathy B Moelans, Anoek HJ Verschuur-Maes, Marieke CH Hogenes, Peter C de Bruin, Joost J Oudejans, Paul J van Diest
Breast density change as a predictive surrogate for response to adjuvant endocrine therapy in hormone receptor positive breast cancer
Jisun Kim, Wonshik Han, Hyeong-Gon Moon, Soo Kyung Ahn, Hee-Chul Shin, Jee-Man You, Sae-Won Han, Seock-Ah Im, Tae-You Kim, Hye Ryoung Koo, Jung Min Chang, Nariya Cho, Woo Kyung Moon, Dong-Young Noh
Mammographic density as a mediator for breast cancer risk: analytic approaches
Tyler J VanderWeele, Hans-Olov Adami, Rulla M Tamimi
Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways
Ritsuko Iwanaga, Chu-An Wang, Douglas S Micalizzi, J Chuck Harrell, Paul Jedlicka, Carol A Sartorius, Peter Kabos, Susan M Farabaugh, Andrew P Bradford, Heide L Ford
Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met
Kelly L Mueller, Julie M Madden, Gina L Zoratti, Charlotte Kuperwasser, Karin List, Julie L Boerner
Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions
Victor P Andrade, Irina Ostrovnaya, Venkatraman E Seshan, Mary Morrogh, Dilip Giri, Narciso Olvera, Marina De Brot, Monica Morrow, Colin B Begg, Tari A King
CD44 rs13347 C>T polymorphism predicts breast cancer risk and prognosis in Chinese populations
Lan Jiang, Jieqiong Deng, Xun Zhu, Jian Zheng, Yonghe You, Na Li, Hongchun Wu, Jiachun Lu, Yifeng Zhou
Hippo inactivation feeds tumor-initiating cells
Stephan Duss, Adrian Britschgi, Mohamed Bentires-Alj
Human pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells
Jhen-Wei Ruan, Yi-Chu Liao, Ingrid Lua, Ming-Hsun Li, Chih-Yi Hsu, Ji-Hshiung Chen
Prolactin-induced protein mediates cell invasion and regulates integrin signaling in estrogen receptor-negative breast cancer
Ali Naderi, Michelle Meyer
Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer
Valerie Cortez, Monica Mann, Seshidhar Tekmal, Takayoshi Suzuki, Naoki Miyata, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Anil K Sood, Ratna K Vadlamudi
Identification of novel human receptor activator of nuclear factor-kB isoforms generated through alternative splicing: implications in breast cancer cell survival and migration
Anastasios D Papanastasiou, Chaido Sirinian, Haralabos P Kalofonos
Variation in breast cancer risk associated with factors related to pregnancies according to truncating mutation location, in the French National BRCA1 and BRCA2 mutations carrier cohort (GENEPSO)
Julie Lecarpentier, Catherine Noguès, Emmanuelle Mouret-Fourme, Marion Gauthier-Villars, Christine Lasset, Jean-Pierre Fricker, Olivier Caron, Dominique Stoppa-Lyonnet, Pascaline Berthet, Laurence Faivre, Valérie Bonadona, Bruno Buecher, Isabelle Coupier, Laurence Gladieff, Paul Gesta, François Eisinger, Marc Frénay, Elisabeth Luporsi, Alain Lortholary, Chrystelle Colas, Catherine Dugast, Michel Longy, Pascal Pujol, Julie Tinat, Rosette Lidereau, Nadine Andrieu
Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer
Christina N Bennett, Christine C Tomlinson, Aleksandra M Michalowski, Isabel M Chu, Dror Luger, Lara R Mittereder, Olga Aprelikova, James Shou, Helen Piwinica-Worms, Natasha J Caplen, Melinda G Hollingshead, Jeffrey E Green
The gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition
Erik Fredlund, Johan Staaf, Juha K Rantala, Olli Kallioniemi, Åke Borg, Markus Ringnér
Height, adiposity and body fat distribution and breast density in young women
Joanne F Dorgan, Catherine Klifa, John A Shepherd, Brian L Egleston, Peter O Kwiterovich Jr, John H Himes, Kelley Pettee Gabriel, Linda Van Horn, Linda G Snetselaar, Victor J Stevens, Bruce A Barton, Alan M Robson, Norman L Lasser, Snehal Deshmukh, Nola M Hylton
Results of a phase II open-label, non-randomized trial of cisplatin chemotherapy in patients with BRCA1-positive metastatic breast cancer
Tomasz Byrski, Rebecca Dent, Pawel Blecharz, Malgorzata Foszczynska-Kloda, Jacek Gronwald, Tomasz Huzarski, Cezary Cybulski, Elzbieta Marczyk, Robert Chrzan, Andrea Eisen, Jan Lubinski, Steven A Narod
The interaction between ER and NFκB in resistance to endocrine therapy
Leen Sas, Filip Lardon, Peter B Vermeulen, Jan Hauspy, Peter Van Dam, Patrick Pauwels, Luc Y Dirix, Steven J Van Laere
Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival
Randi R Mathiesen, Elin Borgen, Anne Renolen, Erik Løkkevik, Jahn M Nesland, Gun Anker, Bjørn Østenstad, Steinar Lundgren, Terje Risberg, Ingvil Mjaaland, Gunnar Kvalheim, Per Eystein Lønning, Bjørn Naume
High-throughput mammographic-density measurement: a tool for risk prediction of breast cancer
Jingmei Li, Laszlo Szekely, Louise Eriksson, Boel Heddson, Ann Sundbom, Kamila Czene, Per Hall, Keith Humphreys
FGFR1 is amplified during the progression of in situto invasive breast carcinoma
Min Hye Jang, Eun Joo Kim, Yoomi Choi, Hee Eun Lee, Yu Jung Kim, Jee Hyun Kim, Eunyoung Kang, Sung-Won Kim, In Ah Kim, So Yeon Park
Reversal by RARα agonist Am580 of c-Myc-induced imbalance in RARα/RARγ expression during MMTV-Myc tumorigenesis
Almudena Bosch, Silvina P Bertran, Yongke Lu, Avalon Garcia, Alexis M Jones, Marcia I Dawson, Eduardo F Farias
Tumour morphology of early-onset breast cancers predicts breast cancer risk for first-degree relatives: the Australian Breast Cancer Family Registry
Gillian S Dite, Enes Makalic, Daniel F Schmidt, Graham G Giles, John L Hopper, Melissa C Southey
A single proteolytic cleavage within the lower hinge of trastuzumab reduces immune effector function and in vivo efficacy
Xuejun Fan, Randall J Brezski, Ming Fa, Hui Deng, Allison Oberholtzer, Anneliese Gonzalez, William P Dubinsky, William R Strohl, Robert E Jordan, Ningyan Zhang, Zhiqiang An
Prognostic impact of circulating tumor cells assessed with the CellSearch System™ and AdnaTest Breast™ in metastatic breast cancer patients: the DETECT study
Volkmar Müller, Sabine Riethdorf, Brigitte Rack, Wolfgang Janni, Peter A Fasching, Erich Solomayer, Bahriye Aktas, Sabine Kasimir-Bauer, Klaus Pantel, Tanja Fehm
Conversion of epidermal growth factor receptor 2 and hormone receptor expression in breast cancer metastases to the brain
Renata Duchnowska, Rafał Dziadziuszko, Tomasz Trojanowski, Tomasz Mandat, Waldemar Och, Bogumiła Czartoryska-Arłukowicz, Barbara Radecka, Wojciech Olszewski, Franciszek Szubstarski, Wojciech Kozłowski, Bożena Jarosz, Wojciech Rogowski, Anna Kowalczyk, Janusz Limon, Wojciech Biernat, Jacek Jassem
Gene-expression profiling of microdissected breast cancer microvasculature identifies distinct tumor vascular subtypes
François Pepin, Nicholas Bertos, Julie Laferrière, Svetlana Sadekova, Margarita Souleimanova, Hong Zhao, Greg Finak, Sarkis Meterissian, Michael T Hallett, Morag Park