Ausgabe 5/2014
Inhalt (37 Artikel)
Prognostic significance of FOXP3+ tumor-infiltrating lymphocytes in breast cancer depends on estrogen receptor and human epidermal growth factor receptor-2 expression status and concurrent cytotoxic T-cell infiltration
Shuzhen Liu, William D Foulkes, Samuel Leung, Dongxia Gao, Sherman Lau, Zuzana Kos, Torsten O Nielsen
Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen–urokinase plasminogen activator receptor system–regulated secretion during breast cancer progression
Agnes Csiszar, Betül Kutay, Silvia Wirth, Ulrike Schmidt, Sabine Macho-Maschler, Martin Schreiber, Memetcan Alacakaptan, Georg F Vogel, Karin Aumayr, Lukas A Huber, Hartmut Beug
Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways
Naveid A Ali, Jianmin Wu, Falko Hochgräfe, Howard Chan, Radhika Nair, Sunny Ye, Luxi Zhang, Ruth J Lyons, Mark Pinese, Hong Ching Lee, Nicola Armstrong, Christopher J Ormandy, Susan J Clark, Alexander Swarbrick, Roger J Daly
Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase
Xiaoyong Fu, Chad J Creighton, Nrusingh C Biswal, Vijetha Kumar, Martin Shea, Sabrina Herrera, Alejandro Contreras, Carolina Gutierrez, Tao Wang, Sarmistha Nanda, Mario Giuliano, Gladys Morrison, Agostina Nardone, Kristen L Karlin, Thomas F Westbrook, Laura M Heiser, Pavana Anur, Paul Spellman, Sylvie M Guichard, Paul D Smith, Barry R Davies, Teresa Klinowska, Adrian V Lee, Gordon B Mills, Mothaffar F Rimawi, Susan G Hilsenbeck, Joe W Gray, Amit Joshi, C Kent Osborne, Rachel Schiff
Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential
Hélène Pelicano, Wan Zhang, Jinyun Liu, Naima Hammoudi, Jiale Dai, Rui-Hua Xu, Lajos Pusztai, Peng Huang
The forkhead transcription factor FOXM1 promotes endocrine resistance and invasiveness in estrogen receptor-positive breast cancer by expansion of stem-like cancer cells
Anna Bergamaschi, Zeynep Madak-Erdogan, Yu Jin Kim, Yoon-La Choi, Hailing Lu, Benita S Katzenellenbogen
The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services
D Gareth R Evans, Julian Barwell, Diana M Eccles, Amanda Collins, Louise Izatt, Chris Jacobs, Alan Donaldson, Angela F Brady, Andrew Cuthbert, Rachel Harrison, Sue Thomas, Anthony Howell, Zosia Miedzybrodzka, Alex Murray
Circulating tumor cells as early predictors of metastatic spread in breast cancer patients with limited metastatic dissemination
Mario Giuliano, Antonio Giordano, Summer Jackson, Ugo De Giorgi, Michal Mego, Evan N Cohen, Hui Gao, Simone Anfossi, Beverly C Handy, Naoto T Ueno, Ricardo H Alvarez, Sabino De Placido, Vicente Valero, Gabriel N Hortobagyi, James M Reuben, Massimo Cristofanilli
miR-638 mediated regulation of BRCA1affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer
Xiaohui Tan, Jin Peng, Yebo Fu, Shejuan An, Katayoon Rezaei, Sana Tabbara, Christine B Teal, Yan-gao Man, Rachel F Brem, Sidney W Fu
Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A–dependent phospho-Akt inactivation in estrogen receptor–negative human breast cancer cells
Chun-Yu Liu, Man-Hsin Hung, Duen-Shian Wang, Pei-Yi Chu, Jung-Chen Su, Tsung-Han Teng, Chun-Teng Huang, Ting-Ting Chao, Cheng-Yi Wang, Chung-Wai Shiau, Ling-Ming Tseng, Kuen-Feng Chen
A novel role for ezrin in breast cancer angio/lymphangiogenesis
Abdi Ghaffari, Victoria Hoskin, Alvin Szeto, Maaike Hum, Navid Liaghati, Kanji Nakatsu, Yolanda Madarnas, Sandip Sengupta, Bruce E Elliott
Digital mammographic density and breast cancer risk: a case–control study of six alternative density assessment methods
Amanda Eng, Zoe Gallant, John Shepherd, Valerie McCormack, Jingmei Li, Mitch Dowsett, Sarah Vinnicombe, Steve Allen, Isabel dos-Santos-Silva
Integrin-mediated resistance to epidermal growth factor receptor-targeted therapy: an inflammatory situation
Wells S Brown, Michael K Wendt
Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation
Laura Barrio-Real, Lorena G Benedetti, Nora Engel, Yaping Tu, Soonweng Cho, Saraswati Sukumar, Marcelo G Kazanietz
Cas proteins: dodgy scaffolding in breast cancer
Giusy Tornillo, Paola Defilippi, Sara Cabodi
Significance of glioma-associated oncogene homolog 1 (GLI1)expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway
Sierra A Colavito, Mike R Zou, Qin Yan, Don X Nguyen, David F Stern
Risk determination and prevention of breast cancer
Anthony Howell, Annie S Anderson, Robert B Clarke, Stephen W Duffy, D Gareth Evans, Montserat Garcia-Closas, Andy J Gescher, Timothy J Key, John M Saxton, Michelle N Harvie
Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers
Yandong Zhang, Kathleen C Baysac, Lian-Fai Yee, Anthony J Saporita, Jason D Weber
Trefoil factor 3 promotes metastatic seeding and predicts poor survival outcome of patients with mammary carcinoma
Vijay Pandey, Zheng-Sheng Wu, Min Zhang, Rui Li, Jian Zhang, Tao Zhu, Peter E Lobie
Risk of contralateral second primary breast cancer according to hormone receptor status in Germany
Carsten Rusner, Katharina Wolf, Ulrike Bandemer-Greulich, Jutta Engel, Christa Stegmaier, Bernd Holleczek, Gabriele Schubert-Fritschle, Anett Tillack, Andreas Stang
Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis
Sergey V Novitskiy, Elizabeth Forrester, Michael W Pickup, Agnieszka E Gorska, Anna Chytil, Mary Aakre, Dina Polosukhina, Philip Owens, Dilyara R Yusupova, Zhiguo Zhao, Fei Ye, Yu Shyr, Harold L Moses
DNA methylation profiling in the Carolina Breast Cancer Study defines cancer subclasses differing in clinicopathologic characteristics and survival
Kathleen Conway, Sharon N Edmiston, Ryan May, Pei Fen Kuan, Haitao Chu, Christopher Bryant, Chiu-Kit Tse, Theresa Swift-Scanlan, Joseph Geradts, Melissa A Troester, Robert C Millikan
Mammographic breast density refines Tyrer-Cuzick estimates of breast cancer risk in high-risk women: findings from the placebo arm of the International Breast Cancer Intervention Study I
Jane Warwick, Hanna Birke, Jennifer Stone, Ruth ML Warren, Elizabeth Pinney, Adam R Brentnall, Stephen W Duffy, Anthony Howell, Jack Cuzick
TP53 mutations detected in circulating tumor cells present in the blood of metastatic triple negative breast cancer patients
Sandra V Fernandez, Catherine Bingham, Patricia Fittipaldi, Laura Austin, Juan Palazzo, Gary Palmer, Katherine Alpaugh, Massimo Cristofanilli
Functional variants at the 21q22.3 locus involved in breast cancer progression identified by screening of genome-wide estrogen response elements
Chia-Ni Hsiung, Hou-Wei Chu, Yuan-Ling Huang, Wen-Cheng Chou, Ling-Yueh Hu, Huan-Ming Hsu, Pei-Ei Wu, Ming-Feng Hou, Jyh-Cherng Yu, Chen-Yang Shen
RETRACTED ARTICLE: Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis
Jun-Tang Li, Li-Feng Wang, Ya-Li Zhao, Tao Yang, Wei Li, Jing Zhao, Feng Yu, Lei Wang, Yan-Ling Meng, Ning-Ning Liu, Xiao-Shan Zhu, Chun-Fang Gao, Lin-Tao Jia, An-Gang Yang
Anatomical localization of progenitor cells in human breast tissue reveals enrichment of uncommitted cells within immature lobules
Lisa M Arendt, Patricia J Keller, Adam Skibinski, Kevin Goncalves, Stephen P Naber, Rachel J Buchsbaum, Hannah Gilmore, Steven E Come, Charlotte Kuperwasser
Methylation profiling of ductal carcinoma in situand its relationship to histopathological features
Jia-Min B Pang, Siddhartha Deb, Elena A Takano, David J Byrne, Nicholas Jene, Alice Boulghourjian, Anne Holliday, Ewan Millar, C Soon Lee, Sandra A O’Toole, Alexander Dobrovic, Stephen B Fox
New concepts in breast cancer genomics and genetics
Rodrigo Goncalves, Wayne A Warner, Jingqin Luo, Matthew J Ellis
Transducin (β)-like 1 X-linked receptor 1 promotes proliferation and tumorigenicity in human breast cancer via activation of beta-catenin signaling
Xinghua Li, Weijiang Liang, Junling Liu, Chuyong Lin, Shu Wu, Libing Song, Zhongyu Yuan
Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway
Heba Alshaker, Jonathan Krell, Adam E Frampton, Jonathan Waxman, Oleg Blyuss, Alexey Zaikin, Mathias Winkler, Justin Stebbing, Ernesto Yagüe, Dmitri Pchejetski
Ubiquitin-specific proteases as therapeutic targets for the treatment of breast cancer
Anupama Pal, Nicholas J Donato
Pathologic response prediction to neoadjuvant chemotherapy utilizing pretreatment near-infrared imaging parameters and tumor pathologic criteria
Quing Zhu, Liqun Wang, Susan Tannenbaum, Andrew Ricci, Patricia DeFusco, Poornima Hegde
β1 and β4 integrins: from breast development to clinical practice
Paola Nisticò, Francesca Di Modugno, Sheila Spada, Mina J Bissell
Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3
Chu-An Wang, J Chuck Harrell, Ritsuko Iwanaga, Paul Jedlicka, Heide L Ford
Identification of chemokine receptors as potential modulators of endocrine resistance in oestrogen receptor–positive breast cancers
Ricardo Ribas, Zara Ghazoui, Qiong Gao, Sunil Pancholi, Aradhana Rani, Anita Dunbier, Mitch Dowsett, Lesley-Ann Martin
P2Y2receptor activation by nucleotides released from highly metastatic breast cancer cells increases tumor growth and invasion via crosstalk with endothelial cells
Hana Jin, So Young Eun, Jong Sil Lee, Sang Won Park, Jae Heun Lee, Ki Churl Chang, Hye Jung Kim