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Breast Cancer Research and Treatment

Ausgabe 1/2014

Inhalt (26 Artikel)

Review

Breast cancer and aging: results of the U13 conference breast cancer panel

M. F. Barginear, H. Muss, G. Kimmick, C. Owusu, E. Mrozek, A. Shahrokni, K. Ballman, A. Hurria

Review

A retrospective study evaluating a fixed low dose capecitabine monotherapy in women with HER-2 negative metastatic breast cancer

Tadeu Ambros, Simon B. Zeichner, John Zaravinos, Alberto J. Montero, Eugene Ahn, Mani Aruna, Lori Kronish, Reshma L. Mahtani, Charles L. Vogel

Preclinical study

Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer

S. Muenst, A. R. Schaerli, F. Gao, S. Däster, E. Trella, R. A. Droeser, M. G. Muraro, P. Zajac, R. Zanetti, W. E. Gillanders, W. P. Weber, S. D. Soysal

Preclinical study

Hypomethylation of the MMP7 promoter and increased expression of MMP7 distinguishes the basal-like breast cancer subtype from other triple-negative tumors

Steven T. Sizemore, Gina M. Sizemore, Christine N. Booth, Cheryl L. Thompson, Paula Silverman, Gurkan Bebek, Fadi W. Abdul-Karim, Stefanie Avril, Ruth A. Keri

Preclinical study

The metastatic potential of triple-negative breast cancer is decreased via caloric restriction-mediated reduction of the miR-17~92 cluster

Lianjin Jin, Meng Lim, Shuping Zhao, Yuri Sano, Brittany A. Simone, Jason E. Savage, Eric Wickstrom, Kevin Camphausen, Richard G. Pestell, Nicole L. Simone

Preclinical study

Cholesterol biosynthesis inhibitors as potent novel anti-cancer agents: suppression of hormone-dependent breast cancer by the oxidosqualene cyclase inhibitor RO 48-8071

Yayun Liang, Cynthia Besch-Williford, Johannes D. Aebi, Benford Mafuvadze, Matthew T. Cook, Xiaoqin Zou, Salman M. Hyder

Preclinical study

A multi-institutional study on the association between BRCA1/BRCA2 mutational status and triple-negative breast cancer in familial breast cancer patients

Moon-Woo Seong, Kyu Hyung Kim, Il Yong Chung, Eunyoung Kang, Jong Won Lee, Sue K. Park, Min Hyuk Lee, Jeong Eon Lee, Dong-Young Noh, Byung Ho Son, Hai-Lin Park, Sung Im Cho, Sung Sup Park, Sung-Won Kim

Preclinical study

Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells

Chun-Yu Liu, Jung-Chen Su, Mei-Huei Ni, Ling-Ming Tseng, Pei-Yi Chu, Duen-Shian Wang, Wei-Tien Tai, Yuan-Ping Kao, Man-Hsin Hung, Chung-Wai Shiau, Kuen-Feng Chen

Preclinical study

HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer

Manoj M. Pillai, Austin E. Gillen, Tomomi M. Yamamoto, Enos Kline, Joseph Brown, Kale Flory, Jay R. Hesselberth, Peter Kabos

Preclinical study

Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells

Tiffany A. Katz, Shauna N. Vasilatos, Emily Harrington, Steffi Oesterreich, Nancy E. Davidson, Yi Huang

Clinical Trial

A prospective assessment of musculoskeletal toxicity and loss of grip strength in breast cancer patients receiving adjuvant aromatase inhibitors and tamoxifen, and relation with BMI

A. Lintermans, K. Van Asten, H. Wildiers, A. Laenen, R. Paridaens, C. Weltens, J. Verhaeghe, D. Vanderschueren, A. Smeets, E. Van Limbergen, K. Leunen, M. R. Christiaens, P. Neven

Clinical Trial

Early myocardial deformation abnormalities in breast cancer survivors

Ben F. Bulten, Annelies M. C. Mavinkurve-Groothuis, Lioe-Fee de Geus-Oei, Anton F. J. de Haan, Chris L. de Korte, Louise Bellersen, Hanneke W. M. van Laarhoven, Livia Kapusta

Clinical Trial

Use of dried blood spots for the determination of serum concentrations of tamoxifen and endoxifen

N. G. L. Jager, H. Rosing, J. H. M. Schellens, J. H. Beijnen, S. C. Linn

Clinical trial

A phase I-II study of the histone deacetylase inhibitor vorinostat plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in locally advanced breast cancer

Yifan Tu, Dawn L. Hershman, Kapil Bhalla, Warren Fiskus, Christine M. Pellegrino, Eleni Andreopoulou, Della Makower, Kevin Kalinsky, Karen Fehn, Susan Fineberg, Abdissa Negassa, Leslie L. Montgomery, Lisa S. Wiechmann, R. Katherine Alpaugh, Min Huang, Joseph A. Sparano

Clinical trial

Randomised, phase II, placebo-controlled, trial of fulvestrant plus vandetanib in postmenopausal women with bone only or bone predominant, hormone-receptor-positive metastatic breast cancer (MBC): the OCOG ZAMBONEY study

Mark J. Clemons, Brandy Cochrane, Gregory R. Pond, Nadia Califaretti, Stephen K. L. Chia, Rebecca Alexandra Dent, Xinni Song, Andre Robidoux, Sameer Parpia, David Warr, Daniel Rayson, Kathleen I. Pritchard, Mark N. Levine

Epidemiology

Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis

Dharanija Madhavan, Markus Wallwiener, Karin Bents, Manuela Zucknick, Juliane Nees, Sarah Schott, Katarina Cuk, Sabine Riethdorf, Andreas Trumpp, Klaus Pantel, Christof Sohn, Andreas Schneeweiss, Harald Surowy, Barbara Burwinkel

Epidemiology

Outcome of triple negative breast cancer: comparison of sporadic and BRCA1-associated cancers

Nadine Tung, Elizabeth Gaughan, Michele R. Hacker, Larissa J. Lee, Brian Alexander, Emily Poles, Stuart J. Schnitt, Judy E. Garber

Epidemiology

Overweight and obesity as poor prognostic factors in locally advanced breast cancer patients

C. Arce-Salinas, J. L. Aguilar-Ponce, C. Villarreal-Garza, F. U. Lara-Medina, D. Olvera-Caraza, A. Alvarado Miranda, D. Flores-Díaz, A. Mohar

Epidemiology

Body mass index, diabetes, and triple-negative breast cancer prognosis

Sarah Tait, Jose M. Pacheco, Feng Gao, Caroline Bumb, Matthew James Ellis, Cynthia X. Ma

Epidemiology

The influence of diabetes severity on receipt of guideline-concordant treatment for breast cancer

Susan A. Sabatino, Trevor D. Thompson, Xiao-Cheng Wu, Steven T. Fleming, Gretchen G. Kimmick, Amy Trentham-Dietz, Rosemary Cress, Roger T. Anderson

Open Access Brief Report

Somatic mutation load of estrogen receptor-positive breast tumors predicts overall survival: an analysis of genome sequence data

Svasti Haricharan, Matthew N. Bainbridge, Paul Scheet, Powel H. Brown

Rebuttal Letter

Determining axillary concordance rate for different injection locations in sentinel node mapping of breast cancer: how ambitious can we get?

Ramin Sadeghi, Mehdi Asadi, Giorgio Treglia, Seyed Rasoul Zakavi, Asiehsadat Fattahi, David N. Krag

Update Onkologie

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