Skip to main content

Breast Cancer Research and Treatment

Ausgabe 1/2015

Inhalt (36 Artikel)

Review

HER2-family signalling mechanisms, clinical implications and targeting in breast cancer

N. Elster, D. M. Collins, S. Toomey, J. Crown, A. J. Eustace, B. T. Hennessy

Preclinical study

Stearidonic acid-enriched flax oil reduces the growth of human breast cancer in vitro and in vivo

K. Subedi, H.-M. Yu, M. Newell, R. J. Weselake, D. Meesapyodsuk, X. Qiu, S. Shah, C. J. Field

Open Access Preclinical study

Inherited predisposition to breast cancer among African American women

Jane E. Churpek, Tom Walsh, Yonglan Zheng, Zakiya Moton, Anne M. Thornton, Ming K. Lee, Silvia Casadei, Amanda Watts, Barbara Neistadt, Matthew M. Churpek, Dezheng Huo, Cecilia Zvosec, Fang Liu, Qun Niu, Rafael Marquez, Jing Zhang, James Fackenthal, Mary-Claire King, Olufunmilayo I. Olopade

Preclinical study

A genetic variant at 12p11 significantly modifies breast cancer risk in a genetically homogenous island population

Terri Patricia McVeigh, Una Mary McVeigh, Karl J. Sweeney, Michael J. Kerin, Nicola Miller

Preclinical study

Obesity-associated systemic interleukin-6 promotes pre-adipocyte aromatase expression via increased breast cancer cell prostaglandin E2 production

Laura W. Bowers, Andrew J. Brenner, Stephen D. Hursting, Rajeshwar R. Tekmal, Linda A. deGraffenried

Preclinical Study

Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer

Heba Alshaker, Qi Wang, Adam E. Frampton, Jonathan Krell, Jonathan Waxman, Mathias Winkler, Justin Stebbing, Colin Cooper, Ernesto Yagüe, Dmitri Pchejetski

Preclinical study

The PI3K/mTOR dual inhibitor P7170 demonstrates potent activity against endocrine-sensitive and endocrine-resistant ER+ breast cancer

Jennifer R. Bean, Sarah R. Hosford, Lynn K. Symonds, Philip Owens, Lloye M. Dillon, Wei Yang, Kevin Shee, Gary N. Schwartz, Jonathan D. Marotti, Kristen E. Muller, Kari M. Rosenkranz, Richard J. Barth, Vivian S. Chen, Veena R. Agarwal, Todd W. Miller

Preclinical study

HDAC inhibition does not induce estrogen receptor in human triple-negative breast cancer cell lines and patient-derived xenografts

Patricia de Cremoux, Mathieu Dalvai, Olivia N’Doye, Fatima Moutahir, Gaëlle Rolland, Olfa Chouchane-Mlik, Franck Assayag, Jacqueline Lehmann-Che, Laurence Kraus-Berthie, André Nicolas, Brian Paul Lockhart, Elisabetta Marangoni, Hugues de Thé, Stéphane Depil, Kerstin Bystricky, Didier Decaudin

Open Access Preclinical Study

Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors

Elizabeth S. Yeh, Melissa A. Abt, Elizabeth G. Hill

Preclinical study

In vivo anti-metastatic effects of uPAR retargeted measles virus in syngeneic and xenograft models of mammary cancer

Yuqi Jing, Marcela Toro Bejarano, Julia Zaias, Jaime R. Merchan

Clinical trial

Effects of the BEAT Cancer physical activity behavior change intervention on physical activity, aerobic fitness, and quality of life in breast cancer survivors: a multicenter randomized controlled trial

Laura Q. Rogers, Kerry S. Courneya, Philip M. Anton, Patricia Hopkins-Price, Steven Verhulst, Sandra K. Vicari, Randall S. Robbs, Robert Mocharnuk, Edward McAuley

Clinical trial

Expression profiling of circulating tumor cells in metastatic breast cancer

Julie E. Lang, Janet H. Scott, Denise M. Wolf, Petr Novak, Vasu Punj, Mark Jesus M. Magbanua, Weizhu Zhu, Neal Mineyev, Christopher M. Haqq, Julia R. Crothers, Laura J. Esserman, Debasish Tripathy, Laura van ’t Veer, John W. Park

Clinical trial

Clinicopathologic characteristics and prognosis of primary squamous cell carcinoma of the breast

Jing Liu, Yang Yu, Jing-yan Sun, Shan-shan He, Xin Wang, Jian Yin, Xu-chen Cao

Clinical Trial

Phase III study on efficacy of taxanes plus bevacizumab with or without capecitabine as first-line chemotherapy in metastatic breast cancer

Hans-Joachim Lück, Kristina Lübbe, Mattea Reinisch, Nicolai Maass, Gabriele Feisel-Schwickardi, Oliver Tomé, Wolfgang Janni, Mustafa Aydogdu, Tanja Neunhöffer, Angelika Ober, Bahriye Aktas, Tjoung-Won Park-Simon, Claudia Schumacher, Heinz-Gert Höffkes, Thomas Illmer, Harald Wagner, Keyur Mehta, Gunter von Minckwitz, Valentina Nekljudova, Sibylle Loibl

Clinical Trial

Phase I/II study of pilaralisib (SAR245408) in combination with trastuzumab or trastuzumab plus paclitaxel in trastuzumab-refractory HER2-positive metastatic breast cancer

Sara Tolaney, Howard Burris, Elaina Gartner, Ingrid A. Mayer, Cristina Saura, Matthew Maurer, Eva Ciruelos, Agustin A. Garcia, Frank Campana, Bin Wu, Yi Xu, Jason Jiang, Eric Winer, Ian Krop

Clinical trial

Weekly paclitaxel and concurrent pazopanib following doxorubicin and cyclophosphamide as neoadjuvant therapy for HER-negative locally advanced breast cancer: NSABP Foundation FB-6, a phase II study

A. R. Tan, H. Johannes, P. Rastogi, S. A. Jacobs, A. Robidoux, P. J. Flynn, M. P. Thirlwell, L. Fehrenbacher, P. J. Stella, R. Goel, T. B. Julian, L. Provencher, M. J. Bury, K. Bhatt, C. E. Geyer Jr., S. M. Swain, E. P. Mamounas, N. Wolmark

Open Access Clinical trial

Phase II, multicenter, open-label, randomized study of YM155 plus docetaxel as first-line treatment in patients with HER2-negative metastatic breast cancer

Michael R. Clemens, Oleg A. Gladkov, Elaina Gartner, Vladimir Vladimirov, John Crown, Joyce Steinberg, Fei Jie, Anne Keating

Epidemiology

Single-nucleotide polymorphisms in DNA bypass polymerase genes and association with breast cancer and breast cancer subtypes among African Americans and Whites

Leila Family, Jeannette T. Bensen, Melissa A. Troester, Michael C. Wu, Carey K. Anders, Andrew F. Olshan

Epidemiology

Incidence of breast cancer in a cohort of 5,135 transgender veterans

George R. Brown, Kenneth T. Jones

Epidemiology

Incidence of BRCA1 and BRCA2 non-founder mutations in patients of Ashkenazi Jewish ancestry

Eric Rosenthal, Kelsey Moyes, Christopher Arnell, Brent Evans, Richard J. Wenstrup

Epidemiology

Reduced risk of axillary lymphatic spread in triple-negative breast cancer

Emil Villiam Holm-Rasmussen, Maj-Britt Jensen, Eva Balslev, Niels Kroman, Tove Filtenborg Tvedskov

Open Access Epidemiology

Breast cancer risk after diagnosis by screening mammography of nonproliferative or proliferative benign breast disease: a study from a population-based screening program

Xavier Castells, Laia Domingo, Josep María Corominas, Isabel Torá-Rocamora, María Jesús Quintana, Marisa Baré, Carmen Vidal, Carmen Natal, Mar Sánchez, Francina Saladié, Joana Ferrer, Mar Vernet, Sonia Servitja, Ana Rodríguez-Arana, Marta Roman, Josep Alfons Espinàs, María Sala

Epidemiology

Immunoassay and Nb2 lymphoma bioassay prolactin levels and mammographic density in premenopausal and postmenopausal women the Nurses’ Health Studies

Megan S. Rice, Shelley S. Tworoger, Kimberly A. Bertrand, Susan E. Hankinson, Bernard A. Rosner, Yvonne B. Feeney, Charles V. Clevenger, Rulla M. Tamimi

Epidemiology

Pregnancy-associated breast cancer in women from Shanghai: risk and prognosis

Kathrin Strasser-Weippl, Ritesh Ramchandani, Lei Fan, Junjie Li, Marc Hurlbert, Dianne Finkelstein, Zhi-Ming Shao, Paul E. Goss

Epidemiology

No effect of scalp cooling on survival among women with breast cancer

J. Lemieux, L. Provencher, L. Perron, J. Brisson, C. Amireault, C. Blanchette, E. Maunsell

Epidemiology

Fulvestrant and male breast cancer: a pooled analysis

Flora Zagouri, Theodoros N. Sergentanis, Dimosthenis Chrysikos, Meletios-Athanasios Dimopoulos, Theodora Psaltopoulou

Epidemiology

Prognostic factors of HER2-positive breast cancer patients who develop brain metastasis: a multicenter retrospective analysis

Naoki Hayashi, Naoki Niikura, Norikazu Masuda, Seiki Takashima, Rikiya Nakamura, Ken-ichi Watanabe, Chizuko Kanbayashi, Mayumi Ishida, Yasuo Hozumi, Michiko Tsuneizumi, Naoto Kondo, Yoichi Naito, Yayoi Honda, Akira Matsui, Tomomi Fujisawa, Risa Oshitanai, Hiroyuki Yasojima, Hideko Yamauchi, Shigehira Saji, Hiroji Iwata

Epidemiology

Greater absolute risk for all subtypes of breast cancer in the US than Malaysia

Hisani N. Horne, C. R. Beena Devi, Hyuna Sung, Tieng Swee Tang, Philip S. Rosenberg, Stephen M. Hewitt, Mark E. Sherman, William F. Anderson, Xiaohong R. Yang

Epidemiology

Thyroid hormone receptor α in breast cancer: prognostic and therapeutic implications

Katarzyna J. Jerzak, Jessica Cockburn, Gregory R. Pond, Kathleen I. Pritchard, Steven A. Narod, Sukhbinder K. Dhesy-Thind, Anita Bane

Open Access Brief Report

Confocal fluorescence microscopy for rapid evaluation of invasive tumor cellularity of inflammatory breast carcinoma core needle biopsies

Jessica Dobbs, Savitri Krishnamurthy, Matthew Kyrish, Ana Paula Benveniste, Wei Yang, Rebecca Richards-Kortum

Erratum

Erratum to: Differences in expression of proliferation-associated genes and RANKL across the menstrual cycle in estrogen receptor-positive primary breast cancer

Ben P. Haynes, Giuseppe Viale, Viviana Galimberti, Nicole Rotmensz, Bianca Gibelli, Ian E. Smith, Mitch Dowsett

Erratum

Erratum to: Efficacy of eribulin in women with metastatic breast cancer: a pooled analysis of two phase 3 studies

Chris Twelves, Javier Cortes, Linda Vahdat, Martin Olivo, Yi He, Peter A. Kaufman, Ahmad Awada

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.