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Breast Cancer Research and Treatment

Ausgabe 2/2013

Inhalt (31 Artikel)

Review

A systematic review on topoisomerase 1 inhibition in the treatment of metastatic breast cancer

Iben Kümler, Nils Brünner, Jan Stenvang, Eva Balslev, Dorte L. Nielsen

Preclinical Study

Are symptomatic guidelines for chemotherapy appropriate to ER-positive screen-detected breast cancer (SDBC)?

Nigel J. Bundred, Ramachandran Prasad, Julie Morris, W. Fiona Knox, Ged Byrne, Shan Cheung, Mary Wilson, Gill Lawrence

Open Access Preclinical study

PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy

Seth A. Wander, Dekuang Zhao, Alexandra H. Besser, Feng Hong, Jianqin Wei, Tan A. Ince, Clara Milikowski, Nanette H. Bishopric, Andy J. Minn, Chad J. Creighton, Joyce M. Slingerland

Preclinical study

TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells

Yu-Peng Liu, Hui-Ling Chen, Cherng-Chyi Tzeng, Pei-Jung Lu, Cheng-Wei Lo, Yu-Cheng Lee, Chih-Hua Tseng, Yeh-Long Chen, Chia-Ning Yang

Preclinical Study

The protective effect of intermittent calorie restriction on mammary tumorigenesis is not compromised by consumption of a high fat diet during refeeding

Olga P. Rogozina, Katai J. Nkhata, Emily J. Nagle, Joseph P. Grande, Margot P. Cleary

Preclinical Study

Tumor STAT3 tyrosine phosphorylation status, as a predictor of benefit from adjuvant chemotherapy for breast cancer

Amir Sonnenblick, Beatrice Uziely, Hovav Nechushtan, Luna Kadouri, Eithan Galun, Jonathan H. Axelrod, Daniela Katz, Hagit Daum, Tamar Hamburger, Bela Maly, Tanir M. Allweis, Tamar Peretz

Open Access Preclinical study

RC0639: phase II study of paclitaxel, trastuzumab, and lapatinib as adjuvant therapy for early stage HER2-positive breast cancer

Alvaro Moreno-Aspitia, Amylou C. Dueck, Ismael Ghanem-Cañete, Tejal Patel, Shaker Dakhil, David Johnson, Sandra Franco, Stephen Kahanic, Gerardo Colon-Otero, Kathleen S. Tenner, Richard Rodeheffer, Ann E. McCullough, Robert B. Jenkins, Frances M. Palmieri, Donald Northfelt, Edith A. Perez

Preclinical Study

Isogenic human mammary epithelial cell lines: novel tools for target identification and validation

Ulrike Ulbricht, Anette Sommer, Georg Beckmann, Manuel Lutzenberger, Henrik Seidel, Bertolt Kreft, Luisella Toschi

Open Access Clinical Trial

PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer

Miguel Martín, Aleix Prat, Álvaro Rodríguez-Lescure, Rosalía Caballero, Mark T. W. Ebbert, Blanca Munárriz, Manuel Ruiz-Borrego, Roy R. L. Bastien, Carmen Crespo, Carole Davis, César A. Rodríguez, José M. López-Vega, Vicente Furió, Ana M. García, Maribel Casas, Matthew J. Ellis, Donald A. Berry, Brandelyn N. Pitcher, Lyndsay Harris, Amparo Ruiz, Eric Winer, Clifford Hudis, Inge J. Stijleman, David P. Tuck, Eva Carrasco, Charles M. Perou, Philip S. Bernard

Clinical Trial

Effects of adjuvant tamoxifen therapy on cardiac disease: results from a randomized trial with long-term follow-up

Johan Rosell, Bo Nordenskjöld, Nils-Olof Bengtsson, Tommy Fornander, Thomas Hatschek, Henrik Lindman, Per-Olof Malmström, Arne Wallgren, Olle Stål, John Carstensen

Clinical Trial

Impact of local surgical treatment on survival in young women with T1 breast cancer: long-term results of a population-based cohort

Ye Won Jeon, Jung Eun Choi, Heung Kyu Park, Ku Sang Kim, Jee Yeon Lee, Young Jin Suh

Clinical trial

Disseminated tumour cells in the bone marrow in early breast cancer: morphological categories of immunocytochemically positive cells have different impact on clinical outcome

M. Synnestvedt, E. Borgen, E. Schlichting, C. B. Schirmer, A. Renolen, K. E. Giercksky, J. M. Nesland, B. Naume

Clinical Trial

Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial

Olöf Bjarnadottir, Quinci Romero, Pär-Ola Bendahl, Karin Jirström, Lisa Rydén, Niklas Loman, Mathias Uhlén, Henrik Johannesson, Carsten Rose, Dorthe Grabau, Signe Borgquist

Clinical Trial

The HER2 status of disseminated tumor cells in the bone marrow of early breast cancer patients is independent from primary tumor and predicts higher risk of relapse

A. D. Hartkopf, M. Banys, F. Meier-Stiegen, M. Hahn, C. Röhm, J. Hoffmann, G. Helms, F. A. Taran, M. Wallwiener, C. Walter, H. Neubauer, D. Wallwiener, T. Fehm

Epidemiology

Variation in tumor natural history contributes to racial disparities in breast cancer stage at diagnosis

Nataliya G. Batina, Amy Trentham-Dietz, Ronald E. Gangnon, Brian L. Sprague, Marjorie A. Rosenberg, Natasha K. Stout, Dennis G. Fryback, Oguzhan Alagoz

Epidemiology

A genome-wide association study to identify genetic susceptibility loci that modify ductal and lobular postmenopausal breast cancer risk associated with menopausal hormone therapy use: a two-stage design with replication

Rebecca Hein, Dieter Flesch-Janys, Norbert Dahmen, Lars Beckmann, Sara Lindström, Nils Schoof, Kamila Czene, Kirstin Mittelstraß, Thomas Illig, Petra Seibold, Sabine Behrens, Keith Humphreys, Jingmei Li, Jianjun Liu, Janet E. Olson, Xianshu Wang, Susan E. Hankinson, Thérèse Truong, Florence Menegaux, Isabel dos Santos Silva, Nichola Johnson, Shou-Tung Chen, Jyh-Cherng Yu, Argyrios Ziogas, Vesa Kataja, Veli-Matti Kosma, Arto Mannermaa, Hoda Anton-Culver, Chen-Yang Shen, Hiltrud Brauch, Julian Peto, Pascal Guénel, Peter Kraft, Fergus J. Couch, Douglas F. Easton, Per Hall, Jenny Chang-Claude

Epidemiology

Confirmation of the reduction of hormone replacement therapy-related breast cancer risk for carriers of the HSD17B1_937_G variant

Ofure Obazee, Christina Justenhoven, Stefan Winter, Jenny Chang-Claude, Anja Rudolph, Petra Seibold, Dieter Flesch-Janys, Ulf Hannelius, Jingmei Li, Keith Humphreys, Per Hall, Graham Giles, Gianluca Severi, Laura Baglietto, Melissa Southey, Sylvia Rabstein, Volker Harth, Anne Lotz, Beate Pesch, Thomas Brüning, Christian Baisch, Yon-Dschun Ko, Ute Hamann, Hiltrud Brauch

Open Access Epidemiology

Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer

Eryn B. Callihan, Dexiang Gao, Sonali Jindal, Traci R. Lyons, Elizabeth Manthey, Susan Edgerton, Alexander Urquhart, Pepper Schedin, Virginia F. Borges

Epidemiology

Postoperative complications and survival of elderly breast cancer patients: a FOCUS study analysis

N. A. de Glas, M. Kiderlen, E. Bastiaannet, A. J. M. de Craen, W. van de Water, C. J. H. van de Velde, G. J. Liefers

Epidemiology

Plasma IGF-1 and IGFBP-3 may be imprecise surrogates for breast concentrations: an analysis of healthy women

Adana A. Llanos, Theodore M. Brasky, Ramona G. Dumitrescu, Catalin Marian, Kepher H. Makambi, Bhaskar V. S. Kallakury, Scott L. Spear, David J. Perry, Rafael J. Convit, Mary E. Platek, Lucile L. Adams-Campbell, Jo L. Freudenheim, Peter G. Shields

Epidemiology

Can we select individuals with low risk ductal carcinoma in situ (DCIS)? A population-based outcomes analysis

Eileen Rakovitch, Sharon Nofech-Mozes, Steven A. Narod, Wedad Hanna, Deva Thiruchelvam, Refik Saskin, Carole Taylor, Alan Tuck, Sandip Sengupta, Leela Elavathil, Prashant A. Jani, Susan J. Done, Naomi Miller, Bruce Youngson, Iwa Kong, Lawrence Paszat

Epidemiology

The prognostic impact of age in patients with triple-negative breast cancer

Cornelia Liedtke, K. R. Hess, T. Karn, A. Rody, L. Kiesel, G. N. Hortobagyi, L. Pusztai, A. M. Gonzalez-Angulo

Epidemiology

Body size throughout the life course and mammographic density in Mexican women

Megan S. Rice, Kimberly A. Bertrand, Martin Lajous, Rulla M. Tamimi, Gabriela Torres-Mejía, Carine Biessy, Ruy López-Ridaura, Isabelle Romieu

Epidemiology

Chronic comorbid conditions associated with risk of febrile neutropenia in breast cancer patients treated with chemotherapy

Victoria M. Chia, John H. Page, Roberto Rodriguez, Su-Jau Yang, Julie Huynh, Chun Chao

Letter to the Editor

Too many statistical errors for meaningful interpretation

A. Stang, E. Kantelhardt

Letter to the Editor

Earwax type and osmidrosis: prognostic factor for breast cancer?

Yang Sun, Jianhong Long

Update Onkologie

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