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Cancer Chemotherapy and Pharmacology

Ausgabe 1/2018

Inhalt (16 Artikel)

Open Access Original Article

Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer

A. A. van Zweeden, C. J. van Groeningen, R. J. Honeywell, E. Giovannetti, R. Ruijter, C. H. Smorenburg, G. Giaccone, H. M. W. Verheul, G. J. Peters, Hans J. van der Vliet

Original Article

Comparison of tumor size assessments in tumor growth inhibition-overall survival models with second-line colorectal cancer data from the VELOUR study

Laurent Claret, Christina Pentafragka, Sanja Karovic, Binsheng Zhao, Lawrence H. Schwartz, Michael L. Maitland, Rene Bruno

Original Article

Timing is everything: intraperitoneal chemotherapy after primary or interval debulking surgery for advanced ovarian cancer

Jessica Lee, John P. Curtin, Franco M. Muggia, Bhavana Pothuri, Leslie R. Boyd, Stephanie V. Blank

Original Article

Sunitinib does not acutely alter left ventricular systolic function, but induces diastolic dysfunction

Takeshi Wada, Kentaro Ando, Atsuhiko T. Naito, Yuji Nakamura, Ai Goto, Koki Chiba, Nur Jaharat Lubna, Xin Cao, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Yuji Nakazato, Atsushi Sugiyama

Original Article

Exposure–response relationship for ramucirumab from the randomized, double-blind, phase 3 REVEL trial (docetaxel versus docetaxel plus ramucirumab) in second-line treatment of metastatic non-small cell lung cancer

Egbert F. Smit, Edward B. Garon, Martin Reck, Federico Cappuzzo, Paolo Bidoli, Roger B. Cohen, Ling Gao, Lisa M. O’Brien, Pablo Lee, Annamaria Zimmermann, David R. Ferry, Allen S. Melemed, Maurice Pérol

Original Article

UGT1A polymorphisms associated with worse outcome in colorectal cancer patients treated with irinotecan-based chemotherapy

Qianqian Yu, Tao Zhang, Conghua Xie, Hong Qiu, Bo Liu, Liu Huang, Ping Peng, Jueping Feng, Jigui Chen, Aihua Zang, Xianglin Yuan

Original Article

Expression of M2 macrophage markers YKL-39 and CCL18 in breast cancer is associated with the effect of neoadjuvant chemotherapy

Nikolai Litviakov, Matvey Tsyganov, Irina Larionova, Marina Ibragimova, Irina Deryusheva, Polina Kazantseva, Elena Slonimskaya, Irina Frolova, Eugeniy Choinzonov, Nadezhda Cherdyntseva, Julia Kzhyshkowska

Original Article

Phase II trial of induction chemotherapy of pemetrexed plus split-dose cisplatin followed by pemetrexed maintenance for untreated non-squamous non-small-cell lung cancer

Taro Koba, Seigo Minami, Yu Nishijima-Futami, Kentaro Masuhiro, Hiromi Kimura, Shinji Futami, Moto Yaga, Masahide Mori, Hiroyuki Kagawa, Takeshi Uenami, Satoshi Kohmo, Tomoyuki Otsuka, Suguru Yamamoto, Kiyoshi Komuta, Takashi Kijima

Original Article

Efficacy and safety of cytotoxic drug chemotherapy after first-line EGFR–TKI treatment in elderly patients with non-small-cell lung cancer harboring sensitive EGFR mutations

Hisao Imai, Hiroyuki Minemura, Tomohide Sugiyama, Yutaka Yamada, Kyoichi Kaira, Kenya Kanazawa, Takashi Kasai, Takayuki Kaburagi, Koichi Minato

Open Access Original Article

Exposure–response analysis of alectinib in crizotinib-resistant ALK-positive non-small cell lung cancer

Peter N. Morcos, Eveline Nueesch, Felix Jaminion, Elena Guerini, Joy C. Hsu, Walter Bordogna, Bogdana Balas, Francois Mercier

Original Article

LAPTM4B gene copy number gain is associated with inferior response to anthracycline-based chemotherapy in hormone receptor negative breast carcinomas

Orsolya Rusz, Orsolya Papp, Laura Vízkeleti, Béla Ákos Molnár, Kristóf Csaba Bende, Gábor Lotz, Balázs Ács, Zsuzsanna Kahán, Tamás Székely, Ágnes Báthori, Csilla Szundi, Janina Kulka, Zoltán Szállási, Anna-Mária Tőkés

Original Article

Possible association of CAG repeat polymorphism in KCNN3 encoding the potassium channel SK3 with oxaliplatin-induced neurotoxicity

Benjamin Anon, Bérenger Largeau, Alban Girault, Aurélie Chantome, Morgane Caulet, Clémence Perray, Driffa Moussata, Christophe Vandier, Chantal Barin-Le Guellec, Thierry Lecomte

Clinical Trial Report

Bioequivalence study of single-dose lenalidomide capsule vs. Revlimid® capsule in healthy Chinese males

Jin Wang, Lu Qi, Zejuan Wang, Gang Chen, Chen Liu, Ying Liu, Xiaona Liu, Yu Wang, Chunpu Lei, Xinghe Wang

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