Ausgabe 3/2019
Inhalt (24 Artikel)
Prophylactic effect of scopolamine butylbromide, a competitive antagonist of muscarinic acetylcholine receptor, on irinotecan-related cholinergic syndrome
Hirotoshi Iihara, Hironori Fujii, Chiaki Yoshimi, Ryo Kobayashi, Nobuhisa Matsuhashi, Takao Takahashi, Kazuhiro Yoshida, Akio Suzuki
Self-targeted knockdown of CD44 improves cisplatin sensitivity of chemoresistant non-small cell lung cancer cells
Yu Hua Quan, Ji-Young Lim, Byeong Hyeon Choi, Yeonho Choi, Young Ho Choi, Ji-Ho Park, Hyun Koo Kim
A phase II trial of the effect of perindopril on hand–foot skin reaction (HFSR) incidence and severity in patients receiving regorafenib for refractory mCRC
Barbara L. Melosky, Howard John Lim, Janine Marie Davies, Sharlene Gill, Christian K. Kollmannsberger, Maria Yi Ho, Solomon A. Vandt, Daniel John Renouf
Randomized phase II trial of the prophylactic use of celecoxib for the prevention of oxaliplatin-related peripheral vascular pain in Capeox (YCOG1205)
Yusuke Suwa, Jun Watanabe, Mitsuyoshi Ota, Shinsuke Suzuki, Hirokazu Suwa, Kazuteru Watanabe, Shuji Saito, Koutaro Nagamine, Masashi Momiyama, Atsushi Ishibe, Yusuke Saigusa, Takeharu Yamanaka, Itaru Endo
Severe hypersensitivity reactions to platinum compounds post-pressurized intraperitoneal aerosol chemotherapy (PIPAC): first literature report
Matthieu Siebert, Mohammad Alyami, Frederic Mercier, Colin Gallice, Laurent Villeneuve, Frédéric Bérard, Olivier Glehen, Naoual Bakrin, Vahan Kepenekian
Dose-dense paclitaxel/carboplatin as neo-adjuvant chemotherapy followed by radical surgery in locally advanced cervical cancer: a prospective phase II study
Gabriella Ferrandina, Giacomo Corrado, Giuseppe Vitrano, Valerio Gallotta, Eleonora Palluzzi, Mariagrazia Distefano, Giovanni Scambia
Low dosage of apatinib monotherapy as rescue treatment in advanced lung squamous cell carcinoma
Da-xiong Zeng, Wei Lei, Chang-guo Wang, Jian-an Huang, Jun-hong Jiang
A retrospective study of the CHOP, CHOPE, and CHOPE/G regimens as the first-line treatment of peripheral T-cell lymphomas
Xuyan Liu, Mingzi Yang, Meng Wu, Wen Zheng, Yan Xie, Jun Zhu, Yuqin Song, Weiping Liu
Targeted disruption of PI3K/Akt/mTOR signaling pathway, via PI3K inhibitors, promotes growth inhibitory effects in oral cancer cells
Sadhna Aggarwal, Sarah John, Leena Sapra, Suresh C. Sharma, Satya N. Das
Evaluation of the effects of formulation, food, or a proton-pump inhibitor on the pharmacokinetics of glasdegib (PF-04449913) in healthy volunteers: a randomized phase I study
Naveed Shaik, Brian Hee, Hua Wei, Robert R. LaBadie
A window-of-opportunity clinical trial of dasatinib in women with newly diagnosed endometrial cancer
Linda R. Duska, Gina R. Petroni, Heather Lothamer, William Faust Jr., Jan H. Beumer, Susan M. Christner, Anne M. Mills, Paula M. Fracasso, Sarah J. Parsons
Evaluation of the effects of an oral notch inhibitor, crenigacestat (LY3039478), on QT interval, and bioavailability studies conducted in healthy subjects
Eunice Yuen, Maria Posada, Claire Smith, Katharine Thorn, Dale Greenwood, Michelle Burgess, Karim A. Benhadji, Demetrio Ortega, Louise Chinchen, Jeffrey Suico
Clinical outcomes of oral metronomic vinorelbine in advanced non-small cell lung cancer: correlations with pharmacokinetics and MDR1 polymorphisms
Milena Gusella, Felice Pasini, Donatella Caruso, Carmen Barile, Yasmina Modena, Anna Paola Fraccon, Laura Bertolaso, Daniela Menon, Giorgio Crepaldi, Antonio Bononi, Roberto Spezzano, Giorgia Anna Telatin, Giuseppe Corona, Roberto Padrini
Safety and efficacy of trastuzumab administered as a 30-min infusion in patients with HER2-positive advanced gastric cancer
Sung Yong Oh, Suee Lee, Seok Jae Huh, Jeeyun Lee, Seung Tae Kim, Se Hoon Park, Ho Yeong Lim, Won Ki Kang, Byung Woog Kang, Jong Gwang Kim, Hyo Jin Lee, Jung Hoon Kim, Jung Hun Kang, HoUng Kim
Pharmacokinetics and bioequivalence of generic and branded abiraterone acetate tablet: a single-dose, open-label, and replicate designed study in healthy Chinese male volunteers
Chunhua Wang, Chaoying Hu, Dan Gao, Zirun Zhao, Xiaoping Chen, Xiao Hu, Shili Gong, Lin Li, Lan Zhang
Anti-liver cancer effect and the mechanism of arsenic sulfide in vitro and in vivo
Shudan Wang, Chao Zhang, Yumei Li, Ping Li, Dafang Zhang, Chaoying Li
Targeting neratinib-induced diarrhea with budesonide and colesevelam in a rat model
Kate R. Secombe, Imogen A. Ball, Joseph Shirren, Anthony D. Wignall, John Finnie, Dorothy Keefe, Francesca Avogadri-Connors, Elizabeth Olek, David Martin, Susan Moran, Joanne M. Bowen
Increase in cetuximab-induced skin rash and hypomagnesemia in patients receiving concomitant treatment with proton pump inhibitors (PPIs): a possible drug interaction?
Mahmoud Abu-Amna, Gil Bar-Sela
Phase 1b trial of nintedanib in combination with bevacizumab in patients with advanced solid tumors
Ravi Paluri, Ankit Madan, Peng Li, Benjamin Jones, Mansoor Saleh, Mary Jerome, Deborah Miley, Jennifer Keef, Francisco Robert
The value of serum cystatin C in early evaluation of renal insufficiency in patients undergoing chemotherapy: a systematic review and meta-analysis
Liyun He, Jine Li, Jinfeng Zhan, Fengming Yi, Xiude Fan, Yiping Wei, Wenxiong Zhang
A successful compartmental approach for the treatment of breast cancer brain metastases
Thuy T. Nguyen, Eurydice Angeli, François Darrouzain, Quang T. Nguyen, Céline Desvignes, Marthe Rigal, Osman Nevine, Patrick Nicolas, Quang V. Le, Sabine Winterman, Marie-Christine Pailler, Laurent Zelek, Gilles Paintaud, Anne Janin, Guilhem Bousquet
Neoadjuvant chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF-RT) for locally advanced esophageal squamous cell carcinoma
Ken Sasaki, Yasuto Uchikado, Itaru Omoto, Takaaki Arigami, Yusaku Osako, Masahiro Noda, Hiroshi Okumura, Kosei Maemura, Ryutaro Higashi, Takashi Yoshiura, Shoji Natsugoe
A phase I trial of intraperitoneal nab-paclitaxel in the treatment of advanced malignancies primarily confined to the peritoneal cavity
Mihaela C. Cristea, Paul Frankel, Timothy Synold, Saul Rivkin, Dean Lim, Vincent Chung, Joseph Chao, Mark Wakabayashi, Benjamin Paz, Ernest Han, Paul Lin, Lucille Leong, Amy Hakim, Mary Carroll, Neal Prakash, Thanh Dellinger, Min Park, Robert J. Morgan
Inflammatory bowel disease associated with the combination treatment of nivolumab and metformin: data from the FDA adverse event reporting system
Huaqiang Zhou, Jiaqing Liu, Yaxiong Zhang, Li Zhang