Ausgabe 5/2019
Inhalt (15 Artikel)
T-cell recognition of non-mutated tumor antigens in healthy individuals: connecting endogenous immunity and tumor dormancy
Constantin N. Baxevanis
Natural T cell autoreactivity to melanoma antigens: clonally expanded melanoma-antigen specific CD8 + memory T cells can be detected in healthy humans
Anna Przybyla, Ting Zhang, Ruliang Li, Diana R. Roen, Andrzej Mackiewicz, Paul V. Lehmann
Imbalances in cellular immunological parameters in blood predetermine tumor onset in a natural mouse model of breast cancer
Dmitry A. Aronov, Viacheslav V. Zhukov, Svetlana G. Semushina, Ekaterina V. Moiseeva
Tumor infiltrating mast cells determine oncogenic HIF-2α-conferred immune evasion in clear cell renal cell carcinoma
Ying Xiong, Li Liu, Yu Xia, Yangyang Qi, Yifan Chen, Lingli Chen, Peipei Zhang, Yunyi Kong, Yang Qu, Zewei Wang, Zhiyuan Lin, Xiang Chen, Zhuoyi Xiang, Jiajun Wang, Qi Bai, Weijuan Zhang, Yuanfeng Yang, Jianming Guo, Jiejie Xu
Melanoma-associated antigen-A and programmed death-ligand 1 expression are associated with advanced urothelial carcinoma
Izak Faiena, Stephanie H. Astrow, David A. Elashoff, Rajul Jain, Adrian Bot, Karim Chamie, Arie S. Belldegrun, Allan J. Pantuck, Alexandra Drakaki
Expression of a soluble IL-10 receptor enhances the therapeutic effects of a papillomavirus-associated antitumor vaccine in a murine model
Jamile R. Silva, Natiely S. Sales, Mariângela O. Silva, Luana R. M. M. Aps, Ana C. R. Moreno, Elaine G. Rodrigues, Luís C. S. Ferreira, Mariana O. Diniz
First-line therapy-stratified survival in BRAF-mutant melanoma: a retrospective multicenter analysis
Bastian Schilling, Alexander Martens, Marnix H. Geukes Foppen, Christoffer Gebhardt, Jessica C. Hassel, Elisa A. Rozeman, Anja Gesierich, Ralf Gutzmer, Katharina C. Kähler, Elisabeth Livingstone, Panagiotis T. Diamantopoulos, Helen Gogas, Gabriele Madonna, Paolo A. Ascierto, Simone M. Goldinger, Johanna Mangana, Claus Garbe, Dirk Schadendorf, Christian Blank, Benjamin Weide
Phase II clinical trial of adoptive cell therapy for patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and low-dose interleukin-2
Linh T. Nguyen, Samuel D. Saibil, Valentin Sotov, Michael X. Le, Leila Khoja, Danny Ghazarian, Luisa Bonilla, Habeeb Majeed, David Hogg, Anthony M. Joshua, Michael Crump, Norman Franke, Anna Spreafico, Aaron Hansen, Ayman Al-Habeeb, Wey Leong, Alexandra Easson, Michael Reedijk, David P. Goldstein, David McCready, Kazuhiro Yasufuku, Thomas Waddell, Marcelo Cypel, Andrew Pierre, Bianzheng Zhang, Sarah Boross-Harmer, Jane Cipollone, Megan Nelles, Elizabeth Scheid, Michael Fyrsta, Charlotte S. Lo, Jessica Nie, Jennifer Y. Yam, Pei Hua Yen, Diana Gray, Vinicius Motta, Alisha R. Elford, Stephanie DeLuca, Lisa Wang, Stephanie Effendi, Ragitha Ellenchery, Naoto Hirano, Pamela S. Ohashi, Marcus O. Butler
Metronomic cyclophosphamide attenuates mTOR-mediated expansion of regulatory T cells, but does not impact clinical outcome in patients with metastatic renal cell cancer treated with everolimus
Inge M. Werter, Charlotte M. Huijts, Sinéad. M. Lougheed, Paul Hamberg, Marco B. Polee, Metin Tascilar, Maartje Los, John B. A. G. Haanen, Helgi H. Helgason, Henk M. Verheul, Tanja D. de Gruijl, Hans J. van der Vliet
A phase I/IIa study of the mRNA-based cancer immunotherapy CV9201 in patients with stage IIIB/IV non-small cell lung cancer
Martin Sebastian, Andreas Schröder, Birgit Scheel, Henoch S. Hong, Anke Muth, Lotta von Boehmer, Alfred Zippelius, Frank Mayer, Martin Reck, Djordje Atanackovic, Michael Thomas, Folker Schneller, Jan Stöhlmacher, Helga Bernhard, Andreas Gröschel, Thomas Lander, Jochen Probst, Tanja Strack, Volker Wiegand, Ulrike Gnad-Vogt, Karl-Josef Kallen, Ingmar Hoerr, Florian von der Muelbe, Mariola Fotin-Mleczek, Alexander Knuth, Sven D. Koch
Monitoring of patients with metastatic melanoma treated with immune checkpoint inhibitors using PET–CT
Antonia Dimitrakopoulou-Strauss
Opposing roles of eosinophils in cancer
Sonja C. S. Simon, Jochen Utikal, Viktor Umansky
Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism
Jingjing Zhu, Pierre-Florent Petit, Benoit J. Van den Eynde
An alphavirus-based therapeutic cancer vaccine: from design to clinical trial
Amrita Singh, Georgia Koutsoumpli, Stephanie van de Wall, Toos Daemen
Modulation of NK cells with checkpoint inhibitors in the context of cancer immunotherapy
Beatriz Sanchez-Correa, Nelson Lopez-Sejas, Esther Duran, Fernando Labella, Corona Alonso, Rafael Solana, Raquel Tarazona