Ausgabe 11/2017
Inhalt (12 Artikel)
Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Chronic Lymphocytic Leukemia: Ibrutinib, Idelalisib, and Venetoclax
Madeline Waldron, Allison Winter, Brian T. Hill
Levetiracetam Clinical Pharmacokinetic Monitoring in Pediatric Patients with Epilepsy
Jason Tan, Vanessa Paquette, Marc Levine, Mary H. H. Ensom
A Review of the Clinical Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Vedolizumab
Maria Rosario, Nathanael L. Dirks, Catherine Milch, Asit Parikh, Michael Bargfrede, Tim Wyant, Eric Fedyk, Irving Fox
Gestation-Specific Changes in the Anatomy and Physiology of Healthy Pregnant Women: An Extended Repository of Model Parameters for Physiologically Based Pharmacokinetic Modeling in Pregnancy
André Dallmann, Ibrahim Ince, Michaela Meyer, Stefan Willmann, Thomas Eissing, Georg Hempel
Population Pharmacokinetic Modeling of JNJ-53718678, a Novel Fusion Inhibitor for the Treatment of Respiratory Syncytial Virus: Results from a Phase I, Double-Blind, Randomized, Placebo-Controlled First-in-Human Study in Healthy Adult Subjects
Dymphy R. H. Huntjens, Sivi Ouwerkerk-Mahadevan, Anne Brochot, Sarah Rusch, Marita Stevens, Rene Verloes
Development of a Pediatric Physiologically-Based Pharmacokinetic Model of Clindamycin Using Opportunistic Pharmacokinetic Data
Christoph P. Hornik, Huali Wu, Andrea N. Edginton, Kevin Watt, Michael Cohen-Wolkowiez, Daniel Gonzalez
Population Pharmacokinetic Analysis of Ixazomib, an Oral Proteasome Inhibitor, Including Data from the Phase III TOURMALINE-MM1 Study to Inform Labelling
Neeraj Gupta, Paul M. Diderichsen, Michael J. Hanley, Deborah Berg, Helgi van de Velde, R. Donald Harvey, Karthik Venkatakrishnan
A Bayesian Approach for Population Pharmacokinetic Modeling of Pegylated Interferon α-2a in Hepatitis C Patients
Mohammad I. Saleh
Pharmacokinetics and Tolerability of a Single Dose of Semaglutide, a Human Glucagon-Like Peptide-1 Analog, in Subjects With and Without Renal Impairment
Thomas C. Marbury, Anne Flint, Jacob B. Jacobsen, Julie Derving Karsbøl, Kenneth Lasseter
Effect of Semaglutide on the Pharmacokinetics of Metformin, Warfarin, Atorvastatin and Digoxin in Healthy Subjects
Helene Hausner, Julie Derving Karsbøl, Anders G. Holst, Jacob B. Jacobsen, Frank-Dietrich Wagner, Georg Golor, Thomas W. Anderson
Time-to-Seizure Modeling of Lacosamide Used in Monotherapy in Patients with Newly Diagnosed Epilepsy
Andreas Lindauer, Christian Laveille, Armel Stockis
No Dose Adjustment is Recommended for Digoxin, Warfarin, Atorvastatin or a Combination Oral Contraceptive When Coadministered with Dulaglutide
Amparo de la Peña, Xuewei Cui, Jeanne Geiser, Corina Loghin