Ausgabe 1/2019
Inhalt (405 Artikel)
Improvement in the survival rates of extracorporeal membrane oxygenation-supported respiratory failure patients: a multicenter retrospective study in Korean patients
Moon Seong Baek, Sang-Min Lee, Chi Ryang Chung, Woo Hyun Cho, Young-Jae Cho, Sunghoon Park, So-My Koo, Jae-Seung Jung, Seung Yong Park, Youjin Chang, Byung Ju Kang, Jung-Hyun Kim, Jin Young Oh, So Hee Park, Jung-Wan Yoo, Yun Su Sim, Sang-Bum Hong
Neurally adjusted ventilatory assist (NAVA) versus pressure support ventilation: patient-ventilator interaction during invasive ventilation delivered by tracheostomy
Olivier Lamouret, Laure Crognier, Fanny Vardon Bounes, Jean-Marie Conil, Caroline Dilasser, Thibaut Raimondi, Stephanie Ruiz, Antoine Rouget, Clément Delmas, Thierry Seguin, Vincent Minville, Bernard Georges
Enteral versus intravenous approach for the sedation of critically ill patients: a randomized and controlled trial
Giovanni Mistraletti, Michele Umbrello, Silvia Salini, Paolo Cadringher, Paolo Formenti, Davide Chiumello, Cristina Villa, Riccarda Russo, Silvia Francesconi, Federico Valdambrini, Giacomo Bellani, Alessandra Palo, Francesca Riccardi, Enrica Ferretti, Maurilio Festa, Anna Maria Gado, Martina Taverna, Cristina Pinna, Alessandro Barbiero, Pier Alda Ferrari, Gaetano Iapichino, Gaetano Iapichino, Alberto Morabito, Martin Langer, Franco Valenza, Roberto Malacrida, Marco Rambaldi, Giovanni Mistraletti, Davide Chiumello, Michele Umbrello, Paolo Formenti, Paolo Spanu, Stefania Anania, Elisa Andrighi, Alessandra Di Carlo, Federica Martinetti, Serena Barello, Andrea Noto, Gianfranco Capello, Bruno Sabatelli, Giovanni Brenna, Morena Astori, Pietro Placido, Luciano Gattinoni, Alessandro Protti, Paolo Cadringher, Riccarda Russo, Francesca Pagan, Virna Berto, Paola Roselli, Giulio Ronzoni, Eduardo Beck, Silvia Francesconi, Maurizio Gaiotto, Danilo Radrizzani, Luca Ferla, Federico Valdambrini, Riccardo Giudici, Laura Merlini, Antonio Pesenti, Giacomo Bellani, Alessia La Bruna, Emanuele Rezoagli, Alberto Lucchini, Antonio Braschi, Alessandra Palo, Thekla Niebel, Marina Selvini, Sergio Cortesi, Attilio Quaini, Giorgio Iotti, Francesca Riccardi, Enrico Contri, Antonella Sacchi, Sergio Livigni, Giuseppe Naretto, Enrica Ferretti, Alessandro Deprado, Virna Venturi degli Esposti, Pietro Caironi, Giulio Radeschi, Maurilio Festa, Lorenzo Odetto, Daniele Ferrero, Stefano Cognolato, Roberto Penso, Roberta Vacchelli, Silvano Cardellino, Edda Bosco, Anna Maria Gado, Anna Bresciani, Ivana Pozzo, Annachiara Alessio, Vanessa Clarindo Rodrigues, Edna Biase, Nicoletta Vivaldi, Martina Taverna, Antonella Nava, Cristina Pinna, Francesco Ponzetta, Lucilla Bavutti, Paola Martina, Beatriz Palacios, Giancarla Bergonzini
Optimal pressing strength and time for capillary refilling time
Rui Kawaguchi, Taka-aki Nakada, Taku Oshima, Masayoshi Shinozaki, Toshiya Nakaguchi, Hideaki Haneishi, Shigeto Oda
Dosing adjuvant vitamin C in critically ill patients undergoing continuous renal replacement therapy: We are not there yet!
Patrick M. Honore, David De Bels, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen
Intact cerebrovascular autoregulation in patients with refractory status epilepticus due to sufficient anesthetic treatment on a neurointensive care unit: a prospective cohort study
Marco Meyer, Martin Juenemann, Tobias Braun, Ingo Schirotzek, Patrick Schramm
Artificial intelligence in the intensive care unit
Christopher A. Lovejoy, Varun Buch, Mahiben Maruthappu
Early diuretic use and mortality in critically ill patients with vasopressor support: a propensity score-matching analysis
Yanfei Shen, Weimin Zhang, Yong Shen
Hyperchloremia-associated acute chronic kidney injury: beware of confounders!
Patrick M. Honore, David De Bels, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen
Predicting mortality in patients undergoing VA-ECMO after coronary artery bypass grafting: the REMEMBER score
Liangshan Wang, Feng Yang, Xiaomeng Wang, Haixiu Xie, Eddy Fan, Mark Ogino, Daniel Brodie, Hong Wang, Xiaotong Hou
Outcomes used in randomised controlled trials of nutrition in the critically ill: a systematic review
Garry Taverny, Thomas Lescot, Emmanuel Pardo, Frederique Thonon, Manar Maarouf, Corinne Alberti
Increased dosing regimens of piperacillin-tazobactam are needed to avoid subtherapeutic exposure in critically ill patients with augmented renal clearance
Thibaud Besnard, Cédric Carrié, Laurent Petit, Matthieu Biais
To remove and replace—a role for plasma exchange in counterbalancing the host response in sepsis
S. David, K. Stahl
Vancomycin pharmacokinetics in critically ill obese patients: can the clinician sit back and relax?
Patrick M. Honore, David De Bels, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen
The glycocalyx: a novel diagnostic and therapeutic target in sepsis
Ryo Uchimido, Eric P. Schmidt, Nathan I. Shapiro
Potential confounders for the effect of high-flow nasal cannula oxygen therapy
Satoshi Yamaga, Shinichiro Ohshimo, Nobuaki Shime
Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury
Wen-Kuang Yu, J. Brennan McNeil, Nancy E. Wickersham, Ciara M. Shaver, Julie A. Bastarache, Lorraine B. Ware
The effects of passive leg raising may be detected by the plethysmographic oxygen saturation signal in critically ill patients
Alexandra Beurton, Jean-Louis Teboul, Francesco Gavelli, Filipe Andre Gonzalez, Valentina Girotto, Laura Galarza, Nadia Anguel, Christian Richard, Xavier Monnet
How to understand real net ultrafiltration and its association with low blood pressure in critically ill patients with renal replacement therapy
Wei Li, Jinsong Zhang, Xufeng Chen
Cerebrospinal fluid procalcitonin predicts Gram-negative bacterial meningitis in patients with empiric antibiotic pretreatment
Wen Li, Fang Yuan, Xiaolong Sun, Zhihan Zhao, Yaoyao Zhang, Wen Jiang
Safety and efficacy of regional citrate anticoagulation for continuous renal replacement therapy in liver failure patients: a systematic review and meta-analysis
Wei Zhang, Ming Bai, Yan Yu, Lu Li, Lijuan Zhao, Shiren Sun, Xiangmei Chen
Bronchoalveolar lavage fluid dilution in ICU patients: what we should know and what we should do
Yuetian Yu, Chunyan Liu, Zhongheng Zhang, Hui Shen, Yujie Li, Liangjing Lu, Yuan Gao
The aftermath of acute kidney injury: a narrative review of long-term mortality and renal function
Gijs Fortrie, Hilde R. H. de Geus, Michiel G. H. Betjes
A smartphone comes to the rescue during tracheostomy
Animesh Ray, Bharath, Sanjeev Sinha, Saurav Sekhar Paul
Host genetic variants in sepsis risk: a field synopsis and meta-analysis
Hongxiang Lu, Dalin Wen, Xu Wang, Lebin Gan, Juan Du, Jianhui Sun, Ling Zeng, Jianxin Jiang, Anqiang Zhang
Comparison of extracorporeal and conventional cardiopulmonary resuscitation: a retrospective propensity score matched study
Daniel Patricio, Lorenzo Peluso, Alexandre Brasseur, Olivier Lheureux, Mirko Belliato, Jean-Louis Vincent, Jacques Creteur, Fabio Silvio Taccone
The effect of diabetes on burn patients: a retrospective cohort study
Reinhard Dolp, Sarah Rehou, Ruxandra Pinto, Rachel Trister, Marc G. Jeschke
The adrenal-vitamin C axis: from fish to guinea pigs and primates
Michael H. Hooper, Anitra Carr, Paul E. Marik
Associations between partial pressure of oxygen and neurological outcome in out-of-hospital cardiac arrest patients: an explorative analysis of a randomized trial
Florian Ebner, Susann Ullén, Anders Åneman, Tobias Cronberg, Niklas Mattsson, Hans Friberg, Christian Hassager, Jesper Kjærgaard, Michael Kuiper, Paolo Pelosi, Johan Undén, Matt P. Wise, Jørn Wetterslev, Niklas Nielsen
Sigh maneuver to enhance assessment of fluid responsiveness during pressure support ventilation
Antonio Messina, Davide Colombo, Federico Lorenzo Barra, Gianmaria Cammarota, Giacomo De Mattei, Federico Longhini, Stefano Romagnoli, Francesco DellaCorte, Daniel De Backer, Maurizio Cecconi, Paolo Navalesi
Humanizing the intensive care unit
Michael E. Wilson, Sarah Beesley, Amanda Grow, Eileen Rubin, Ramona O. Hopkins, Negin Hajizadeh, Samuel M. Brown
Electrophysiological investigations of peripheral nerves and muscles: a method for looking at cell dysfunction in the critically ill patients
Nicola Latronico, Oliver Friedrich
Organizational factors associated with target sedation on the first 48 h of mechanical ventilation: an analysis of checklist-ICU database
Antonio Paulo Nassar Jr, Fernando G. Zampieri, Jorge I. Salluh, Fernando A. Bozza, Flávia Ribeiro Machado, Helio Penna Guimarães, Lucas P. Damiani, Alexandre Biasi Cavalcanti
Is fluid resuscitation the “Keyser Soze” of acute kidney injury in trauma patients?
Matthieu Jamme, Omar Ben Hadj Salem
The ELSO Maastricht Treaty for ECLS Nomenclature: abbreviations for cannulation configuration in extracorporeal life support - a position paper of the Extracorporeal Life Support Organization
Lars Mikael Broman, Fabio Silvio Taccone, Roberto Lorusso, Maximilian Valentin Malfertheiner, Federico Pappalardo, Matteo Di Nardo, Mirko Belliato, Melania M. Bembea, Ryan P. Barbaro, Rodrigo Diaz, Lorenzo Grazioli, Vincent Pellegrino, Malaika H. Mendonca, Daniel Brodie, Eddy Fan, Robert H. Bartlett, Michael M. McMullan, Steven A. Conrad
Passive leg cycling and electrical stimulation cannot preserve strength in sepsis
Pierre-François Laterre, Cheryl Hickmann, Diego Castanares-Zapatero
Letter on “Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis”
Venu M. Velagapudi, Dennis A. Tighe
Impact of post-traumatic stress symptoms on the health-related quality of life in a cohort study with chronically critically ill patients and their partners: age matters
Gloria-Beatrice Wintermann, Katja Petrowski, Kerstin Weidner, Bernhard Strauß, Jenny Rosendahl
The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study
Kordo Saeed, Darius Cameron Wilson, Frank Bloos, Philipp Schuetz, Yuri van der Does, Olle Melander, Pierre Hausfater, Jacopo M. Legramante, Yann-Erick Claessens, Deveendra Amin, Mari Rosenqvist, Graham White, Beat Mueller, Maarten Limper, Carlota Clemente Callejo, Antonella Brandi, Marc-Alexis Macchi, Nicholas Cortes, Alexander Kutz, Peter Patka, María Cecilia Yañez, Sergio Bernardini, Nathalie Beau, Matthew Dryden, Eric C. M. van Gorp, Marilena Minieri, Louisa Chan, Pleunie P. M. Rood, Juan Gonzalez del Castillo
Low-dose atrial natriuretic peptide for prevention or treatment of acute kidney injury: a systematic review and meta-analysis
Hiroyuki Yamada, Kent Doi, Tatsuo Tsukamoto, Hideyasu Kiyomoto, Kazuto Yamashita, Motoko Yanagita, Yoshio Terada, Kiyoshi Mori
Thromboxane–prostaglandin receptor antagonist, terutroban, prevents neurovascular events after subarachnoid haemorrhage: a nanoSPECT study in rats
David Lagier, David Tonon, Philippe Garrigue, Benjamin Guillet, Laura Giacomino, Jean-Charles Martin, Marie-Christine Alessi, Nicolas Bruder, Lionel J. Velly
Lung fluid biomarkers for acute respiratory distress syndrome: a systematic review and meta-analysis
Yishan Wang, Huijuan Wang, Chunfang Zhang, Chao Zhang, Huqin Yang, Ruiyue Gao, Zhaohui Tong
Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury
Yue Zhou, Pengfei Li, Andrew J. Goodwin, James A. Cook, Perry V. Halushka, Eugene Chang, Basilia Zingarelli, Hongkuan Fan
Cerebral metabolism is not affected by moderate hyperventilation in patients with traumatic brain injury
Giovanna Brandi, Nino Stocchetti, Alberto Pagnamenta, Federica Stretti, Peter Steiger, Stephanie Klinzing
Predicting clinical outcome in patients undergoing VA-ECMO
Antoine Kimmoun, Bruno Levy
NephroCheck: should we consider urine osmolality?
Alberto Noto, Andrea Cortegiani, Antonio David
Assessment of intestinal perfusion by a new balloon-tipped transpyloric probe
Samir G. Sakka
Association of preadmission metformin use and mortality in patients with sepsis and diabetes mellitus: a systematic review and meta-analysis of cohort studies
Huoyan Liang, Xianfei Ding, Lifeng Li, Tian Wang, Quancheng Kan, Lexin Wang, Tongwen Sun
Invasive and non-invasive diagnostic approaches for microbiological diagnosis of hospital-acquired pneumonia
Otavio T. Ranzani, Tarek Senussi, Francesco Idone, Adrian Ceccato, Gianluigi Li Bassi, Miquel Ferrer, Antoni Torres
The clinical impacts and risk factors for non-central line-associated bloodstream infection in 5046 intensive care unit patients: an observational study based on electronic medical records
Shichao Zhu, Yan Kang, Wen Wang, Lin Cai, Xin Sun, Zhiyong Zong
Designing nutrition-based interventional trials for the future: addressing the known knowns
Danielle E. Bear, Zudin A. Puthucheary
The role of impaired brain perfusion in septic encephalopathy
Lucia Rivera-Lara
Impact of acute renal failure on plasmatic levels of cleaved endocan
Alexandre Gaudet, Erika Parmentier, Nathalie De Freitas Caires, Lucie Portier, Sylvain Dubucquoi, Julien Poissy, Thibault Duburcq, Maxence Hureau, Philippe Lassalle, Daniel Mathieu
Letter on “Synbiotics modulate gut microbiota and reduce enteritis and ventilator-associated pneumonia in patients with sepsis: a randomized controlled trial”
Alexander Reisinger, Vanessa Stadlbauer
Soluble vascular endothelial cadherin: a promising marker of critical illness?
Ruyuan Zhang, Ranran Li, Yaoqing Tang
Authors’ response to letter “Prediction of acute kidney injury in intensive care unit patients”
Hiroyuki Naruse, Hiroshi Takahashi, Junnichi Ishii
Response to “Are fluids resuscitation the “Keyser Soze” of acute kidney injury in trauma patients?”
Anatole Harrois, Benjamin Soyer, Tobias Gauss, Sophie Hamada, Mathieu Raux, Jacques Duranteau, Catherine Paugam-Burtz, Romain Pirracchio, Anne Godier, Sylvain Ausset, Eric Meaudre, Thomas Geeraerts, Nathalie Delhaye, Bernard Vigué
Prognostic accuracy of the Hamilton Early Warning Score (HEWS) and the National Early Warning Score 2 (NEWS2) among hospitalized patients assessed by a rapid response team
Shannon M. Fernando, Alison E. Fox-Robichaud, Bram Rochwerg, Pierre Cardinal, Andrew J. E. Seely, Jeffrey J. Perry, Daniel I. McIsaac, Alexandre Tran, Steven Skitch, Benjamin Tam, Michael Hickey, Peter M. Reardon, Peter Tanuseputro, Kwadwo Kyeremanteng
Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest: an analysis of the TTH48 trial
Chiara De Fazio, Markus B. Skrifvars, Eldar Søreide, Jacques Creteur, Anders M. Grejs, Jesper Kjærgaard, Timo Laitio, Jens Nee, Hans Kirkegaard, Fabio Silvio Taccone
Diagnostic and therapeutic approach in adult patients with traumatic brain injury receiving oral anticoagulant therapy: an Austrian interdisciplinary consensus statement
Marion Wiegele, Herbert Schöchl, Alexander Haushofer, Martin Ortler, Johannes Leitgeb, Oskar Kwasny, Ronny Beer, Cihan Ay, Eva Schaden
Acute neuropathological consequences of short-term mechanical ventilation in wild-type and Alzheimer’s disease mice
Shouri Lahiri, Giovanna C. Regis, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Elizabeth H. Kim, Mitra Mastali, Jennifer E. Van Eyk, Padmesh S. Rajput, Patrick D. Lyden, Keith L. Black, E. Wesley Ely, Heather D. Jones, Maya Koronyo-Hamaoui
Emergency department triage prediction of clinical outcomes using machine learning models
Yoshihiko Raita, Tadahiro Goto, Mohammad Kamal Faridi, David F. M. Brown, Carlos A. Camargo Jr., Kohei Hasegawa
The prognostic value of optic nerve sheath diameter in patients with subarachnoid hemorrhage
Sangkil Lee, Yong Oh Kim, Ji Sun Baek, Jeong-Am Ryu
The chemical, biological, radiological and nuclear (CBRN) chain of survival: a new pragmatic and didactic tool used by Paris Fire Brigade
Franck Calamai, Clément Derkenne, Daniel Jost, Stéphane Travers, Isabelle Klein, Kilian Bertho, Frédéric Dorandeu, Michel Bignand, Bertrand Prunet
Association of extracerebral organ failure with 1-year survival and healthcare-associated costs after cardiac arrest: an observational database study
Pirkka T. Pekkarinen, Minna Bäcklund, Ilmar Efendijev, Rahul Raj, Daniel Folger, Erik Litonius, Ruut Laitio, Stepani Bendel, Sanna Hoppu, Tero Ala-Kokko, Matti Reinikainen, Markus B. Skrifvars
Early nasal high-flow versus Venturi mask oxygen therapy after lung resection: a randomized trial
Mariano Alberto Pennisi, Giuseppe Bello, Maria Teresa Congedo, Luca Montini, Dania Nachira, Gian Maria Ferretti, Elisa Meacci, Elisabetta Gualtieri, Gennaro De Pascale, Domenico Luca Grieco, Stefano Margaritora, Massimo Antonelli
Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: a multicentre randomized clinical pilot trial
Mark J. Peters, Kerry Woolfall, Imran Khan, Elisabeth Deja, Paul R. Mouncey, Jerome Wulff, Alexina Mason, Rachel S. Agbeko, Elizabeth S. Draper, Blaise Fenn, Doug W. Gould, Abby Koelewyn, Nigel Klein, Christine Mackerness, Sian Martin, Lauran O’Neill, Samiran Ray, Padmanabhan Ramnarayan, Shane Tibby, Kentigern Thorburn, Lyvonne Tume, Jason Watkins, Paul Wellman, David A. Harrison, Kathryn M. Rowan
Subjective right ventricle assessment by echo qualified intensive care specialists: assessing agreement with objective measures
Sam Orde, Michel Slama, Konstantin Yastrebov, Anthony Mclean, Stephen Huang, Andras Nyikovics, Deirdre Murphy, Geoff Gordon, Lewis Campbell, Li Tan, Mate Rudas, Michael Farqharson, Nicola Stanley, Pierre Janin, Russell Laver, Soumya Ray, Vinodh Nanjayya, Ramsy D’Souza, Paul Healey, Bradley Wibrow, Florian Pracher, Kyle Brooks, David Clancy, Thomas Hamp, Sebastian Knudsen, Joe McCaffrey, Godfrey Lo, Sutrisno Gunawan, Arvind Rajamani, Marek Nalos, Ian Seppelt, Alison Main, Yang Yang, Andrew Hilton, Pranesh Jogia, Jude Bhathan, John Evans, Priya Nair, Lyndal Russel, Mani Gopal, Matthew Anstey, Josh Ihle, Alvin Teo, Ben Cheung, Matt Brian, Richard Strickland, Cartan Costello, Peter McCanny, Siew Wai, Irma Bilgram
Important methodological flaws in the recently published clinical prediction model the REMEMBER score
Anders Granholm, Anders Perner, Aksel Karl Georg Jensen, Morten Hylander Møller
Recruitment Maneuvers and Higher PEEP, the So-Called Open Lung Concept, in Patients with ARDS
Philip van der Zee, Diederik Gommers
ARDS in Obese Patients: Specificities and Management
Audrey De Jong, Daniel Verzilli, Samir Jaber
Physiological and Technical Considerations of Extracorporeal CO2 Removal
Christian Karagiannidis, Felix Hesselmann, Eddy Fan
Mechanical Circulatory Support Devices for Cardiogenic Shock: State of the Art
Ludhmila Abrahao Hajjar, Jean-Louis Teboul
Resuscitation Fluid Choices to Preserve the Endothelial Glycocalyx
Elissa M. Milford, Michael C. Reade
Uncovering Consciousness in Unresponsive ICU Patients: Technical, Medical and Ethical Considerations
Benjamin Rohaut, Andrey Eliseyev, Jan Claassen
Multidrug Resistant Gram-Negative Bacteria in Community-Acquired Pneumonia
Catia Cillóniz, Cristina Dominedò, Antoni Torres
Heterogeneity in sepsis: new biological evidence with clinical applications
Aleksandra Leligdowicz, Michael A. Matthay
Iron Metabolism: An Emerging Therapeutic Target in Critical Illness
Edward Litton, Jolene Lim
Sleep and Circadian Rhythm in Critical Illness
Irene Telias, Mary Elizabeth Wilcox
Organ system network analysis and biological stability in critically ill patients
Toshifumi Asada, Kent Doi, Ryota Inokuchi, Naoki Hayase, Miyuki Yamamoto, Naoto Morimura
Validity of the relationship between mobility group box-1 protein and poor post–cardiac arrest neurological outcome during renal replacement therapy
Patrick M. Honore, David De Bels, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen
Incidence of hypotension according to the discontinuation order of vasopressors: a matter of pharmacokinetics
Ross Freebairn, Brigitte Hollander
The complex kinetics of blood endocan during the time course of sepsis and acute respiratory distress syndrome
Alexandre Gaudet, Erika Parmentier, Sylvain Dubucquoi, Julien Poissy, Thibault Duburcq, Lucie Portier, Philippe Lassalle, Nathalie De Freitas Caires, Daniel Mathieu
Response to “Weaning order of vasoactive drugs”
Kyeongman Jeon, Jae-Uk Song, Gee Young Suh
The pharmacokinetic challenge of voriconazole therapy for cerebral aspergillosis in patients treated with ibrutinib
Rémy Nyga, Laura Simon, Taieb Chouaki, Caroline Delette, Youssef Bennis, Cedric Joseph, Jean-Pierre Marolleau, Michel Slama, Elie Zogheib, Julien Maizel
Transfusion requirements after head trauma: a randomized feasibility controlled trial
André L. N. Gobatto, Milena A. Link, Davi J. Solla, Estevão Bassi, Paulo F. Tierno, Wellingson Paiva, Fabio S. Taccone, Luiz M. Malbouisson
The effects and safety of vasopressin receptor agonists in patients with septic shock: a meta-analysis and trial sequential analysis
Libing Jiang, Yi Sheng, Xia Feng, Jing Wu
State-level hospital compliance with and performance in the Centers for Medicaid & Medicare Services’ Early Management Severe Sepsis and Septic Shock Bundle
Jordan A. Kempker, Michael R. Kramer, Lance A. Waller, Henry E. Wang, Greg S. Martin
The association between autoimmune disease and 30-day mortality among sepsis ICU patients: a cohort study
Mallory Sheth, Corey M. Benedum, Leo Anthony Celi, Roger G. Mark, Natasha Markuzon
Is cortical perfusion a reliable marker for predicting septic acute kidney injury?
Patrick M. Honore, David De Bels, Andrea Gallerani, Rachid Attou, Sebastien Redant, Leonel Barreto Gutierrez, Willem Boer
Development of a quality indicator set to measure and improve quality of ICU care for patients with traumatic brain injury
Jilske A. Huijben, Eveline J. A. Wiegers, Nicolette F. de Keizer, Andrew I. R. Maas, David Menon, Ari Ercole, Giuseppe Citerio, Fiona Lecky, Lindsay Wilson, Maryse C. Cnossen, Suzanne Polinder, Ewout W. Steyerberg, Mathieu van der Jagt, Hester F. Lingsma, Marcel Aries, Rafael Badenes, Albertus Beishuizen, Federico Bilotta, Arturo Chieregato, Emiliano Cingolani, Giuseppe Citerio, Maryse Cnossen, Mark Coburn, Jonathan P. Coles, Mark Delargy, Bart Depreitere, Ari Ercole, Hans Flaatten, Volodymyr Golyk, Erik Grauwmeijer, Iain Haitsma, Raimund Helbok, Cornelia Hoedemaekers, Bram Jacobs, Korné Jellema, Lars-Owe D. Koskinen, Andrew I. R. Maas, Marc Maegele, Maria Cruz Martin Delgado, David Menon, Kirsten Møller, Rui Moreno, David Nelson, Annemarie W. Oldenbeuving, Jean-Francois Payen, Suzanne Polinder, Jasmina Pejakovic, Gerard M. Ribbbers, Rolf Rossaint, Guus Geurt Schoonman, Luzius A. Steiner, Nino Stocchetti, Fabio Silvio Taccone, Riikka Takala, Olli Tenovuo, Eglis Valeinis, Walter M. van den Bergh, Mathieu van der Jagt, Thomas van Essen, Nikki van Leeuwen, Michael H. J. Verhofstad, Pieter E. Vos, Lindsay Wilson
Some questions about preadmission metformin use and mortality in patients with sepsis and diabetes mellitus
Jiarong Ye, Qianrong Liang, Xiaotu Xi
Pediatric ARDS biomarkers: missing the random forest for the trees
Nadir Yehya
The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition
Donat R. Spahn, Bertil Bouillon, Vladimir Cerny, Jacques Duranteau, Daniela Filipescu, Beverley J. Hunt, Radko Komadina, Marc Maegele, Giuseppe Nardi, Louis Riddez, Charles-Marc Samama, Jean-Louis Vincent, Rolf Rossaint
The effect of corticosteroids on mortality of patients with influenza pneumonia: a systematic review and meta-analysis
Yue-Nan Ni, Guo Chen, Jiankui Sun, Bin-Miao Liang, Zong-An Liang
A meta-analysis of the resuscitative effects of mechanical and manual chest compression in out-of-hospital cardiac arrest patients
Ni Zhu, Qi Chen, Zhixia Jiang, Futuan Liao, Bujin Kou, Hui Tang, Manhong Zhou
Time to epinephrine treatment is associated with the risk of mortality in children who achieve sustained ROSC after traumatic out-of-hospital cardiac arrest
Yan-Ren Lin, Meng-Huan Wu, Tren-Yi Chen, Yuan-Jhen Syue, Mei-Chueh Yang, Tsung-Han Lee, Chih-Ming Lin, Chu-Chung Chou, Chin-Fu Chang, Chao-Jui Li
PO2 oscillations induce lung injury and inflammation
Stefan Boehme, Erik K. Hartmann, Thomas Tripp, Serge C. Thal, Matthias David, Dietmar Abraham, James E. Baumgardner, Klaus Markstaller, Klaus U. Klein
Dysphagia in the intensive care unit: epidemiology, mechanisms, and clinical management
Patrick Zuercher, Céline S. Moret, Rainer Dziewas, Joerg C. Schefold
Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique—SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d’Anesthésie et Réanimation—SFAR)
Romain Guilhaumou, Sihem Benaboud, Youssef Bennis, Claire Dahyot-Fizelier, Eric Dailly, Peggy Gandia, Sylvain Goutelle, Sandrine Lefeuvre, Nicolas Mongardon, Claire Roger, Julien Scala-Bertola, Florian Lemaitre, Marc Garnier
Safety and efficacy of volume-based feeding in critically ill, mechanically ventilated adults using the ‘Protein & Energy Requirements Fed for Every Critically ill patient every Time’ (PERFECT) protocol: a before-and-after study
Sue Brierley-Hobson, Graham Clarke, Vincent O’Keeffe
Flagellin attenuates experimental sepsis in a macrophage-dependent manner
Xiaoliang Yang, Yibing Yin, Xingxing Yan, Zebo Yu, Yi Liu, Ju Cao
Death after awakening from post-anoxic coma: the “Best CPC” project
Fabio Silvio Taccone, Janneke Horn, Christian Storm, Alain Cariou, Claudio Sandroni, Hans Friberg, Cornelia Astrid Hoedemaekers, Mauro Oddo
Cytokine clearance with CytoSorb® during cardiac surgery: a pilot randomized controlled trial
Elettra C Poli, Lorenzo Alberio, Anna Bauer-Doerries, Carlo Marcucci, Aurélien Roumy, Matthias Kirsch, Eleonora De Stefano, Lucas Liaudet, Antoine G Schneider
Is intravenous vitamin C contraindicated in patients with G6PD deficiency?
Paul E. Marik
Sequential organ failure assessment score is an excellent operationalization of disease severity of adult patients with hospitalized community acquired pneumonia – results from the prospective observational PROGRESS study
Peter Ahnert, Petra Creutz, Katrin Horn, Fabian Schwarzenberger, Michael Kiehntopf, Hamid Hossain, Michael Bauer, Frank Martin Brunkhorst, Konrad Reinhart, Uwe Völker, Trinad Chakraborty, Martin Witzenrath, Markus Löffler, Norbert Suttorp, Markus Scholz, Stefan Angermair, Christoph Arntzen, Lorenz Balke, Robert Bals, Michael Benzke, Ayhan Berber, Frank Bloos, Martin Buchenroth, Lea Deterding, Nicolas Dickgreber, Oleg Dmitriev, Hermann Druckmiller, Holger Flick, Ulrike Föllmer, Julia Freise, Carmen Garcia, Sven Gläser, Christian Grah, Simone Hamberger, Karsten Hartung, Barabara Hauptmeier, Matthias Held, Frederik Hempel, Iris Hering, Carola Hobler, Andreas Hocke, Ursula Hoffmann, Henning Kahnert, Oliver Kanwar, Lena Kappauf, Charlotte Keller, Nils Keller, Walter Knüppel, Eva Koch, Martin Kolditz, Christine Krollmann, Cornelia Kropf-Sanchen, Josefa Lehmke, Christian Lensch, Andreas Liebrich, Achim Lies, Katrin Ludewig, Lena-Maria Makowski, Phillippr Mayer, Brigitte Mayer, Agata Mikolajewska, Anne Moeser, Thomas Müller, Michaela Niebank, Markus Niesen, Tim Oqueka, Wulf Pankow, Judith Pannier, Claus Peckelsen, Mathias Plauth, Mathias Pletz, Jan Pluta, Kalina Popkirova, Jessicar Rademache, Mirja Ramke, Felix Rosenow, Stefan Rüdiger, Bernhard Ruf, Jan Rupp, Bernhard Schaaf, Tom Schaberg, Marianne Schelle, Patrick Schmidt-Schridde, Galina Schott, Barbara Schröder, Tetyana Shchetynska-Marinova, Michael Simpfendörfer, Thomas Spinner, Norbert Suttorp, Dorina Thiemig, Daniel Thomas-Rüddel, Markus Unnewehr, Barbara Wagener, Gudrun Wakonigg, Deborah Wehde, Hubert Wirtz, Charite ICU-Teams
Impact of nutrition route on microaspiration in critically ill patients with shock: a planned ancillary study of the NUTRIREA-2 trial
Saad Nseir, Amélie Le Gouge, Jean-Baptiste Lascarrou, Jean-Claude Lacherade, Emmanuelle Jaillette, Jean-Paul Mira, Emmanuelle Mercier, Pierre-Louis Declercq, Michel Sirodot, Gaël Piton, François Tinturier, Elisabeth Coupez, Stéphane Gaudry, Michel Djibré, Didier Thevenin, Jeremy Pasco, Malika Balduyck, Farid Zerimech, Jean Reignier
Machine learning for the prediction of volume responsiveness in patients with oliguric acute kidney injury in critical care
Zhongheng Zhang, Kwok M. Ho, Yucai Hong
Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis
David F. Colón, Carlos W. Wanderley, Marcelo Franchin, Camila M. Silva, Carlos H. Hiroki, Fernanda V. S. Castanheira, Paula B. Donate, Alexandre H. Lopes, Leila C. Volpon, Silvia K. Kavaguti, Vanessa F. Borges, Cesar A. Speck-Hernandez, Fernando Ramalho, Ana P. Carlotti, Fabio Carmona, Jose C. Alves-Filho, Foo Y. Liew, Fernando Q. Cunha
Lack of relationship between fasting plasma citrulline and glucose absorption: do not underestimate the role of the failing kidney!
Patrick M. Honore, David De Bels, Andrea Gallerani, Rachid Attou, Willem Boer
What is the lowest change in cardiac output that transthoracic echocardiography can detect?
Mathieu Jozwiak, Pablo Mercado, Jean-Louis Teboul, Anouar Benmalek, Julia Gimenez, François Dépret, Christian Richard, Xavier Monnet
Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels
Nicole A. M. Dekker, Anoek L. I. van Leeuwen, Willem W. J. van Strien, Jisca Majolée, Robert Szulcek, Alexander B. A. Vonk, Peter L. Hordijk, Christa Boer, Charissa E. van den Brom
Cardiovascular determinants of resuscitation from sepsis and septic shock
Fabio Guarracino, Pietro Bertini, Michael R. Pinsky
Heterogeneity of regional inflection points from pressure-volume curves assessed by electrical impedance tomography
Gaetano Scaramuzzo, Savino Spadaro, Andreas D. Waldmann, Stephan H. Böhm, Riccardo Ragazzi, Elisabetta Marangoni, Valentina Alvisi, Elena Spinelli, Tommaso Mauri, Carlo Alberto Volta
Neurally adjusted ventilatory assist decreases work of breathing during non-invasive ventilation in infants with severe bronchiolitis
Florent Baudin, Guillaume Emeriaud, Sandrine Essouri, Jennifer Beck, Etienne Javouhey, Claude Guerin
Comment on the article: “Microvascular effects of intravenous esmolol in patients with normal cardiac function undergoing postoperative atrial fibrillation: a prospective pilot study in cardiothoracic surgery”
Ye Ying Zheng, Fei Guo, Bin Lu, Qiang Li
Mechanical ventilation causes diaphragm dysfunction in newborn lambs
Feng Liang, Guillaume Emeriaud, Dilson E. Rassier, Dong Shang, Ekaterina Gusev, Sabah N. A. Hussain, Michael Sage, Benjamin Crulli, Etienne Fortin-Pellerin, Jean-Paul Praud, Basil J. Petrof
Broad spectrum vasopressors: a new approach to the initial management of septic shock?
Lakhmir S. Chawla, Marlies Ostermann, Lui Forni, George F. Tidmarsh
A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome
Heidi Flori, Anil Sapru, Michael W. Quasney, Ginny Gildengorin, Martha A. Q. Curley, Michael A. Matthay, Mary K. Dahmer, Scot T. Bateman, M. D. Berg, Santiago Borasino, G. Kris Bysani, Allison S. Cowl, Cindy Darnell Bowens, E. Vincent S. Faustino, Lori D. Fineman, A. J. Godshall, Ellie Hirshberg, Aileen L. Kirby, Gwenn E. McLaughlin, Shivanand Medar, Phineas P. Oren, James B. Schneider, Adam J. Schwarz, Thomas P. Shanley, Lauren R. Sorce, Edward J. Truemper, Michele A. Vander Heyden, Kim Wittmayer, Athena Zuppa, David Wypij
Application of MR-ProADM to predict prevention of hospitalisation, derived from a multi-centre study
Milo Cullinan, Sara Graziadio, David Ashley Price
Sedation practices and clinical outcomes in mechanically ventilated patients in a prospective multicenter cohort
Romina E. Aragón, Alvaro Proaño, Nicole Mongilardi, Aldo de Ferrari, Phabiola Herrera, Rollin Roldan, Enrique Paz, Amador A. Jaymez, Eduardo Chirinos, Jose Portugal, Rocio Quispe, Roy G. Brower, William Checkley
TCR activation mimics CD127lowPD-1high phenotype and functional alterations of T lymphocytes from septic shock patients
Julie Mouillaux, Camille Allam, Morgane Gossez, Thomas Uberti, Benjamin Delwarde, Jack Hayman, Thomas Rimmelé, Julien Textoris, Guillaume Monneret, Estelle Peronnet, Fabienne Venet
Liberal versus conservative oxygen therapy in critically ill patients: using the fragility index to determine robust results
Maria Vargas, Giuseppe Servillo
vvECMO can be avoided by a transpulmonary pressure guided open lung concept in patients with severe ARDS
Philip van der Zee, Dinis Dos Reis Miranda, Han Meeder, Henrik Endeman, Diederik Gommers
Control of respiratory drive by extracorporeal CO2 removal in acute exacerbation of COPD breathing on non-invasive NAVA
Christian Karagiannidis, Stephan Strassmann, Sarah Schwarz, Michaela Merten, Eddy Fan, Jennifer Beck, Christer Sinderby, Wolfram Windisch
Intelligently learning from data
Edward Palmer, Roman Klapaukh, Steve Harris, Mervyn Singer, Tim Bonnici, Ahmed Al-Hindawi, Tom Keen
Response to “Incidence of hypotension according to the discontinuation order of vasopressors: a matter of pharmacokinetics”
Kyeongman Jeon, Jae-Uk Song, Gee Young Suh
Trial sequential analysis suggested the potential overestimated effect of carbonic anhydrase inhibitor for respiratory failure and metabolic alkalosis
Meng-Si Luo, Hui-Zi Li, Guan-Jiang Huang, Lun Wu
Composed endotypes to guide antibiotic discontinuation in sepsis
Jesus F. Bermejo-Martin, David Andaluz-Ojeda, Marta Martin-Fernandez, Cesar Aldecoa, Raquel Almansa
Biomarkers to guide antibiotic timing and administration in infected patients presenting to the emergency department
Mari Rosenqvist, Darius Cameron Wilson, Lena Tegnér, Maria Bengtsson-Toni, Marjaneh Peyman, Juan Gonzalez del Castillo, Kordo Saeed, Olle Melander
Correction to: Early versus late initiation of renal replacement therapy impacts mortality in patients with acute kidney injury post cardiac surgery: a meta-analysis
Honghong Zou, Qianwen Hong, Gaosi XU
Epidemiology of infective endocarditis in French intensive care units over the 1997–2014 period—from CUB-Réa Network
Jérémie Joffre, Guillaume Dumas, Philippe Aegerter, Vincent Dubée, Naike Bigé, Gabriel Preda, Jean-Luc Baudel, Eric Maury, Bertrand Guidet, Hafid Ait-Oufella, P. Trouiller, J.-P. Bedos, A. Vieillard-Baron, Y. Cohen, C. Richard, J. F. Timsit, G. Chevrel, J.-P. Mira, D. Da Silva, J.-L. Diehl, P. Ho, A. Mekontso-Dessap, F. Blot, G. Dhonneur, D. Dreyfuss, B. Megarbane, Goldgran Toledano Dany, V. Das, D. Samuel, A. Demoule, A. Combes, F. Bolgert, H. Outin, F. Santoli, D. Annane, B. Guidet, C. Bruel, E. Azoulay, A. Mebazaa, M. Fartoukh, F. Bonnet, H. Mentec
Angiotensin II in ECMO patients: a word of caution
Elio Antonucci, Fabio Silvio Taccone
Optimizing ceftolozane-tazobactam dosage in critically ill patients during continuous venovenous hemodiafiltration
Gerardo Aguilar, Rafael Ferriols, Sara Martínez-Castro, Carlos Ezquer, Ernesto Pastor, José A. Carbonell, Manuel Alós, David Navarro
Quality and quantity of sample size is crucial in clinical studies to exclude association: antimicrobial exposure and the risk of delirium in critically ill patients
Rashid Nadeem, Zainab Ameer Obeida, Sahish Kamat, Ahmed Nazir Elsousi
Renin-angiotensin-aldosterone system blockers after KDIGO stage 3 acute kidney injury: use and impact on 2-year mortality in the AKIKI trial
Mathilde Scarton, Anne Oppenheimer, Khalil Chaïbi, Didier Dreyfuss, Stéphane Gaudry
The global challenge of Candida auris in the intensive care unit
Andrea Cortegiani, Giovanni Misseri, Antonino Giarratano, Matteo Bassetti, David Eyre
Procalcitonin is an essential biomarker for hydrocortisone, ascorbic acid, and thiamine (HAT) therapy in patients with sepsis
Paul E. Marik
Influenza and associated co-infections in critically ill immunosuppressed patients
Ignacio Martin-Loeches, Virginie Lemiale, Pierce Geoghegan, Mary Aisling McMahon, Peter Pickkers, Marcio Soares, Anders Perner, Tine Sylvest Meyhoff, Ramin Brandt Bukan, Jordi Rello, Philippe R. Bauer, Andry van de Louw, Fabio Silvio Taccone, Jorge Salluh, Pleun Hemelaar, Peter Schellongowski, Katerina Rusinova, Nicolas Terzi, Sangeeta Mehta, Massimo Antonelli, Achille Kouatchet, Pål Klepstad, Miia Valkonen, Precious Pearl Landburg, Andreas Barratt-Due, Fabrice Bruneel, Frédéric Pène, Victoria Metaxa, Anne Sophie Moreau, Virginie Souppart, Gaston Burghi, Christophe Girault, Ulysses V. A. Silva, Luca Montini, Francois Barbier, Lene B. Nielsen, Benjamin Gaborit, Djamel Mokart, Sylvie Chevret, Elie Azoulay
Social and economic problems of ICU survivors identified by a structured social welfare consultation
J. M. McPeake, P. Henderson, G. Darroch, T. J. Iwashyna, P. MacTavish, C. Robinson, T. Quasim
When circulatory death does not come in time in potential organ donors
Angela Kotsopoulos, Nichon Jansen, Wilson Farid Abdo
Quantitative pupillometry for the monitoring of intracranial hypertension in patients with severe traumatic brain injury
Fritz-Patrick Jahns, John Paul Miroz, Mahmoud Messerer, Roy T. Daniel, Fabio Silvio Taccone, Philippe Eckert, Mauro Oddo
Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials
Shalini Santhakumaran, Anthony Gordon, A. Toby Prevost, Cecilia O’Kane, Daniel F. McAuley, Manu Shankar-Hari
Does training level affect the accuracy of visual assessment of capillary refill time?
Koichiro Shinozaki, Lee S. Jacobson, Kota Saeki, Naoki Kobayashi, Steve Weisner, Julianne M. Falotico, Timmy Li, Junhwan Kim, Joshua W. Lampe, Lance B. Becker
Retrospective cohort study of hospital variation in airway management during in-hospital cardiac arrest and the association with patient survival: insights from Get With The Guidelines-Resuscitation
Steven M. Bradley, Yunshu Zhou, Satya Krishna Ramachandran, Milo Engoren, Michael Donnino, Saket Girotra
Fluid management in patients undergoing cardiac surgery: effects of an acetate- versus lactate-buffered balanced infusion solution on hemodynamic stability (HEMACETAT)
Carmen A. Pfortmueller, Livia Faeh, Martin Müller, Balthasar Eberle, Hansjörg Jenni, Björn Zante, Josef Prazak, Lars Englberger, Jukka Takala, Stephan M. Jakob
How I monitor cerebral autoregulation
Samuel P. Klein, Bart Depreitere, Geert Meyfroidt
The effect of adhesive tape versus endotracheal tube fastener in critically ill adults: the endotracheal tube securement (ETTS) randomized controlled trial
Janna S. Landsperger, Jesse M. Byram, Bradley D. Lloyd, Todd W. Rice, David R. Janz
Pyroglutamic acidosis by glutathione regeneration blockage in critical patients with septic shock
Yenifer Gamarra, Felipe C. Santiago, Jorge Molina-López, José Castaño, Lourdes Herrera-Quintana, Álvaro Domínguez, Elena Planells
Renal function after out-of-hospital cardiac arrest; the influence of temperature management and coronary angiography, a post hoc study of the target temperature management trial
Malin Rundgren, Susann Ullén, Matt P. G. Morgan, Guy Glover, Julius Cranshaw, Nawaf Al-Subaie, Andrew Walden, Michael Joannidis, Marlies Ostermann, Josef Dankiewicz, Niklas Nielsen, Matthew P. Wise
Hypothermia after decompressive hemicraniectomy in treatment of malignant middle cerebral artery stroke: comment on the randomized clinical trial
N. Engrand, M. Mazighi, V. Dinkelacker
Adding an orange to the banana bag: vitamin C deficiency is common in alcohol use disorders
Paul E. Marik, Amanda Liggett
Inducible metabolic pathway for citrate metabolism in case of major liver dysfunction: fact or fiction?
Patrick M. Honore, David De Bels, Sebastien Redant, Rachid Attou, Luc Kugener, Willem Boer
Letter in response to “Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury”
Richard W Pierce
Comparative efficacy of vasoactive medications in patients with septic shock: a network meta-analysis of randomized controlled trials
Lu Cheng, Jing Yan, Shutang Han, Qiuhua Chen, Mingqi Chen, Hua Jiang, Jun Lu
Nuclear magnetic resonance-based serum metabolomic analysis reveals different disease evolution profiles between septic shock survivors and non-survivors
Zhicheng Liu, Mohamed N. Triba, Roland Amathieu, Xiangping Lin, Nadia Bouchemal, Edith Hantz, Laurence Le Moyec, Philippe Savarin
Is systematic fecal carriage screening of extended-spectrum beta-lactamase-producing Enterobacteriaceae still useful in intensive care unit: a systematic review
Renaud Prevel, Alexandre Boyer, Fatima M’Zali, Agnès Lasheras, Jean-Ralph Zahar, Anne-Marie Rogues, Didier Gruson
Near-infrared spectroscopy after out-of-hospital cardiac arrest
Pekka Jakkula, Johanna Hästbacka, Matti Reinikainen, Ville Pettilä, Pekka Loisa, Marjaana Tiainen, Erika Wilkman, Stepani Bendel, Thomas Birkelund, Anni Pulkkinen, Minna Bäcklund, Sirkku Heino, Sari Karlsson, Hiski Kopponen, Markus B. Skrifvars
Temporal change in characteristics and outcomes of acute kidney injury on renal replacement therapy in intensive care units: analysis of a nationwide administrative database in Japan, 2007–2016
Yoshihisa Miyamoto, Masao Iwagami, Shotaro Aso, Hideo Yasunaga, Hiroki Matsui, Kiyohide Fushimi, Yoshifumi Hamasaki, Masaomi Nangaku, Kent Doi
The challenge of removal of sepsis markers by continuous hemofiltration
Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Kianoush Kashani
Should ECMO be used in cardiogenic shock?
Orhan Gokalp, Koksal Donmez, Hasan Iner, Gamze Gokalp, Yuksel Besir, Nihan Karakas Yesilkaya, Levent Yilik, Ali Gurbuz
Patterns of utilization and effects of hospital-specific factors on physical, occupational, and speech therapy for critically ill patients with acute respiratory failure in the USA: results of a 5-year sample
Clare C. Prohaska, Peter D. Sottile, Amy Nordon-Craft, Matt D. Gallagher, Ellen L. Burnham, Brendan J. Clark, Michael Ho, Tyree H. Kiser, R. William Vandivier, Wenhui Liu, Margaret Schenkman, Marc Moss
How I manage a difficult intubation
Jonathan D. Casey, Matthew W. Semler, Kevin High, Wesley H. Self
Are we really preventing lung collapse with APRV?
Ryota Sato, Natsumi Hamahata, Ehab G. Daoud
Time course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study
Claire Roger, Laurent Zieleskiewicz, Christophe Demattei, Karim Lakhal, Gael Piton, Benjamin Louart, Jean-Michel Constantin, Russell Chabanne, Jean-Sébastien Faure, Yazine Mahjoub, Isabelle Desmeulles, Hervé Quintard, Jean-Yves Lefrant, Laurent Muller, Claire Roger, Laurent Zieleskiewicz, Karim Lakhal, Benjamin Louart, Jean-Michel Constantin, Russell Chabanne, Jean-Sébastien Faure, Yazine Mahjoub, Hervé Quintard, Jean-Yves Lefrant, Laurent Muller
High-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients after planned extubation: a systematic review and meta-analysis
Youfeng Zhu, Haiyan Yin, Rui Zhang, Xiaoling Ye, Jianrui Wei
An overview of positive cultures and clinical outcomes in septic patients: a sub-analysis of the Prehospital Antibiotics Against Sepsis (PHANTASi) trial
Rishi S. Nannan Panday, Eline M. J. Lammers, Nadia Alam, Prabath W. B. Nanayakkara
How to treat combined respiratory and metabolic acidosis after extracorporeal cardiopulmonary resuscitation?
Xavier Bemtgen, Florentine Schroth, Tobias Wengenmayer, Paul M. Biever, Daniel Duerschmied, Christoph Benk, Christoph Bode, Dawid L. Staudacher
Endocan removal during continuous renal replacement therapy: does it affect the reliability of this biomarker?
Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Andrea Gallerani, Kianoush Kashani
Clinically relevant pharmacokinetic knowledge on antibiotic dosing among intensive care professionals is insufficient: a cross-sectional study
Lucas M. Fleuren, Luca F. Roggeveen, Tingjie Guo, Petr Waldauf, Peter H. J. van der Voort, Rob J. Bosman, Eleonora L. Swart, Armand R. J. Girbes, Paul W. G. Elbers
Describing organ dysfunction in the intensive care unit: a cohort study of 20,000 patients
Andrea Soo, Danny J. Zuege, Gordon H. Fick, Daniel J. Niven, Luc R. Berthiaume, Henry T. Stelfox, Christopher J. Doig
Identifying patients’ support needs following critical illness: a scoping review of the qualitative literature
J. King, B. O’Neill, P. Ramsay, M. A. Linden, A. Darweish Medniuk, J. Outtrim, B. Blackwood
Letter on “Sigh maneuver to enhance assessment of fluid responsiveness during pressure support ventilation”
Khaoula Meddeb, Mohamed Boussarsar
Red blood cell transfusion may be more detrimental than anemia for the clinical outcome of patients with severe traumatic brain injury
Santiago R. Leal-Noval, María D. Rincón-Ferrari, Manuel Múñoz-Gómez
Procalcitonin levels in candidemia versus bacteremia: a systematic review
Andrea Cortegiani, Giovanni Misseri, Mariachiara Ippolito, Matteo Bassetti, Antonino Giarratano, Ignacio Martin-Loeches, Sharon Einav
Albumin infusion rate and plasma volume expansion: a randomized clinical trial in postoperative patients after major surgery
Svajunas Statkevicius, Johan Bonnevier, Jane Fisher, Björn P. Bark, Erik Larsson, Carl M. Öberg, Päivi Kannisto, Bobby Tingstedt, Peter Bentzer
Continuous monitoring of intrinsic PEEP based on expired CO2 kinetics: an experimental validation study
Sarah Heili-Frades, Fernando Suarez-Sipmann, Arnoldo Santos, Maria Pilar Carballosa, Alba Naya-Prieto, Carlos Castilla-Reparaz, Maria Jesús Rodriguez-Nieto, Nicolás González-Mangado, German Peces -Barba
Acute kidney injury after cardiac arrest: the role of coronary angiography and temperature management
Angélique M. E. Spoelstra-de Man, Heleen M. Oudemans-van Straaten
Automated continuous noninvasive ward monitoring: future directions and challenges
Ashish K. Khanna, Phillip Hoppe, Bernd Saugel
Dysbiosis of the intestinal microbiota in neurocritically ill patients and the risk for death
Ruoting Xu, Chuhong Tan, Jiajia Zhu, Xiuli Zeng, Xuxuan Gao, Qiheng Wu, Qiong Chen, Huidi Wang, Hongwei Zhou, Yan He, Suyue Pan, Jia Yin
Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis
Jean-Louis Vincent, Gabriel Jones, Sholto David, Elena Olariu, Kevin K. Cadwell
Post-stroke treatment with argon attenuated brain injury, reduced brain inflammation and enhanced M2 microglia/macrophage polarization: a randomized controlled animal study
Jingjin Liu, Kay Nolte, Gary Brook, Lisa Liebenstund, Agnieszka Weinandy, Anke Höllig, Michael Veldeman, Antje Willuweit, Karl-Josef Langen, Rolf Rossaint, Mark Coburn
Short-term assist devices in postcardiotomy cardiogenic shock
Hasan Iner, Nihan Karakas Yesilkaya, Yuksel Besir, Gamze Gokalp, Orhan Gokalp, Levent Yilik, Ali Gurbuz
Trying to identify who may benefit most from future vitamin D intervention trials: a post hoc analysis from the VITDAL-ICU study excluding the early deaths
Gennaro Martucci, Dayre McNally, Dhruv Parekh, Paul Zajic, Fabio Tuzzolino, Antonio Arcadipane, Kenneth B. Christopher, Harald Dobnig, Karin Amrein
Effect of high-flow nasal therapy on dyspnea, comfort, and respiratory rate
Andrea Cortegiani, Claudia Crimi, Alberto Noto, Yigal Helviz, Antonino Giarratano, Cesare Gregoretti, Sharon Einav
In-hospital mortality associated with the misdiagnosis or unidentified site of infection at admission
Toshikazu Abe, Yasuharu Tokuda, Atsushi Shiraishi, Seitaro Fujishima, Toshihiko Mayumi, Takehiro Sugiyama, Gautam A. Deshpande, Yasukazu Shiino, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Akiyoshi Hagiwara, Kazuma Yamakawa, Naoshi Takeyama, Satoshi Gando, Satoshi Gando, Toshikazu Abe, Kohji Okamoto, Seitaro Fujishima, Junichi Sasaki, Yasukazu Shiino, Yasuhiro Otomo, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Toru Hifumi, Kazuma Yamakawa, Toshihiko Mayumi, Atsushi Shiraishi, Akiyoshi Hagiwara, Takashi Muroya, Kaoru Koike, Hideaki Anan, Manabu Sugita, Yasuo Miki, Hisashi Yamashita, Hirotada Kittaka, Junichi Maehara, Sho Nachi, Kazuma Morino, Atsumi Hoshino, Hiroyuki Yamaguchi, Masahiro Harada, Hiroyasu Ishikura, Masato Kawakami, Yoshizumi Deguchi, Hideaki Yoshihara, Yoshihiro Hanaki, Kunihiko Okada, Tadashi Kaneko, Kazuya Kiyota, Yoshihiro Shimizu
ELS (Ethical Life Support): a new teaching tool for medical ethics
Marco Vergano, Giuseppe Naretto, Fabrizio Elia, Enrico Gandolfo, Chiara Nebris Calliera, Giuseppe R. Gristina
Population pharmacokinetics of total and unbound concentrations of intravenous posaconazole in adult critically ill patients
Fekade B. Sime, Catherine J. Byrne, Suzanne Parker, Janine Stuart, Jenie Butler, Therese Starr, Saurabh Pandey, Steven C. Wallis, Jeffrey Lipman, Jason A. Roberts
Reversal of oral anticoagulation in patients with acute intracerebral hemorrhage
Joji B. Kuramatsu, Jochen A. Sembill, Hagen B. Huttner
Examining the weekend effect across ICU performance metrics
Louis Faust, Keith Feldman, Nitesh V. Chawla
The ecological effects of selective decontamination of the digestive tract (SDD) on antimicrobial resistance: a 21-year longitudinal single-centre study
Sophie Buitinck, Rogier Jansen, Saskia Rijkenberg, Jos P. J. Wester, Rob J. Bosman, Nardo J. M. van der Meer, Peter H. J. van der Voort
Decompressive craniectomy for acute ischemic stroke
Thomas Beez, Christopher Munoz-Bendix, Hans-Jakob Steiger, Kerim Beseoglu
Interventions to improve cardiopulmonary resuscitation: a review of meta-analyses and future agenda
Athanasios Chalkias, John P. A. Ioannidis
Mottling score is a strong predictor of 14-day mortality in septic patients whatever vasopressor doses and other tissue perfusion parameters
Guillaume Dumas, Jean-Rémi Lavillegrand, Jérémie Joffre, Naïke Bigé, Edmilson Bastos de-Moura, Jean-Luc Baudel, Sylvie Chevret, Bertrand Guidet, Eric Maury, Fabio Amorim, Hafid Ait-Oufella
Aetiology and outcomes of sepsis in adults in sub-Saharan Africa: a systematic review and meta-analysis
Joseph M. Lewis, Nicholas A. Feasey, Jamie Rylance
Prevalence of post-traumatic stress disorder symptoms in adult critical care survivors: a systematic review and meta-analysis
Cássia Righy, Regis Goulart Rosa, Rodrigo Teixeira Amancio da Silva, Renata Kochhann, Celina Borges Migliavaca, Caroline Cabral Robinson, Stefania Pigatto Teche, Cassiano Teixeira, Fernando Augusto Bozza, Maicon Falavigna
Influenza virus-related critical illness: prevention, diagnosis, treatment
Eric J. Chow, Joshua D. Doyle, Timothy M. Uyeki
Influence of pathogen and focus of infection on procalcitonin values in sepsis: are there additional confounding factors?
Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Andrea Gallerani, Kianoush Kashani
How to achieve nutrition goals by actual nutrition guidelines
Christian Stoppe, Jean-Charles Preiser, Daren Heyland
Detailed measurements of oesophageal pressure during mechanical ventilation with an advanced high-resolution manometry catheter
Per Persson, Rebecca Ahlstrand, Magni Gudmundsson, Alex de Leon, Stefan Lundin
Benefits of red blood cell transfusion in patients with traumatic brain injury
Weimin Zhang, Kailei Du, Xuping Chen
Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project
Matteo Bassetti, Daniele R. Giacobbe, Antonio Vena, Cecilia Trucchi, Filippo Ansaldi, Massimo Antonelli, Vaclava Adamkova, Cristiano Alicino, Maria-Panagiota Almyroudi, Enora Atchade, Anna M. Azzini, Novella Carannante, Alessia Carnelutti, Silvia Corcione, Andrea Cortegiani, George Dimopoulos, Simon Dubler, José L. García-Garmendia, Massimo Girardis, Oliver A. Cornely, Stefano Ianniruberto, Bart Jan Kullberg, Katrien Lagrou, Clement Le Bihan, Roberto Luzzati, Manu L. N. G. Malbrain, Maria Merelli, Ana J. Marques, Ignacio Martin-Loeches, Alessio Mesini, José-Artur Paiva, Maddalena Peghin, Santi Maurizio Raineri, Riina Rautemaa-Richardson, Jeroen Schouten, Pierluigi Brugnaro, Herbert Spapen, Polychronis Tasioudis, Jean-François Timsit, Valentino Tisa, Mario Tumbarello, Charlotte H. S. B. van den Berg, Benoit Veber, Mario Venditti, Guillaume Voiriot, Joost Wauters, Philippe Montravers
Impact of weekly case-based tele-education on quality of care in a limited resource medical intensive care unit
Pedja Kovacevic, Sasa Dragic, Tijana Kovacevic, Danica Momcicevic, Emir Festic, Rahul Kashyap, Alexander S. Niven, Yue Dong, Ognjen Gajic
Videolaryngoscopy in critically ill patients
Samir Jaber, Audrey De Jong, Paolo Pelosi, Luca Cabrini, Jean Reignier, Jean Baptiste Lascarrou
The association between nutritional adequacy and 28-day mortality in the critically ill is not modified by their baseline nutritional status and disease severity
Charles Chin Han Lew, Gabriel Jun Yung Wong, Ka Po Cheung, Robert J. L. Fraser, Ai Ping Chua, Mary Foong Fong Chong, Michelle Miller
Adopting a smart toothbrush with artificial intelligence may improve oral care in patients admitted to the intensive care unit
Tommaso Scquizzato, Arianna Gazzato
Beyond dichotomy: patterns and amplitudes of SSEPs and neurological outcomes after cardiac arrest
Sang Hoon Oh, Kyu Nam Park, Seung Pill Choi, Joo Suk Oh, Han Joon Kim, Chun Song Youn, Soo Hyun Kim, Kiyuk Chang, Seong Hoon Kim
Clinical use of [TIMP-2]•[IGFBP7] biomarker testing to assess risk of acute kidney injury in critical care: guidance from an expert panel
Louis M. Guzzi, Tobias Bergler, Brian Binnall, Daniel T. Engelman, Lui Forni, Michael J. Germain, Eric Gluck, Ivan Göcze, Michael Joannidis, Jay L. Koyner, V. Seenu Reddy, Thomas Rimmelé, Claudio Ronco, Julien Textoris, Alexander Zarbock, John A. Kellum
Matrix metalloproteinase-8: a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission?
Fabrice Uhel, Brendon P. Scicluna, Lonneke A. van Vught, Olaf L. Cremer, Marc J. Bonten, Marcus J. Schultz, Tom van der Poll
Interventions aimed at healthcare professionals to increase the number of organ donors: a systematic review
Marloes Witjes, Nichon E. Jansen, Johannes G. van der Hoeven, Wilson F. Abdo
Attainment of therapeutic vancomycin level within the first 24 h
Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Andrea Gallerani, Kianoush Kashani
New-onset QT prolongation is a novel predictor of mortality in critically ill patients
Yonghe Ding, Ryounghoon Jeon, Linyu Ran, Wenzhi Pan, Feilong Wang, Qiang Li
Prognostic value of NT-proBNP levels in the acute phase of sepsis on lower long-term physical function and muscle strength in sepsis survivors
Carlo Custodero, Quran Wu, Gabriela L. Ghita, Stephen D. Anton, Scott C. Brakenridge, Babette A. Brumback, Philip A. Efron, Anna K. Gardner, Christiaan Leeuwenburgh, Lyle L. Moldawer, John W. Petersen, Frederick A. Moore, Robert T. Mankowski
Individualized recombinant human thrombomodulin (ART-123) administration in sepsis patients based on predicted phenotypes
Daisuke Hasegawa, Osamu Nishida
Hemodynamic goal-directed therapy and postoperative kidney injury: an updated meta-analysis with trial sequential analysis
Mariateresa Giglio, Lidia Dalfino, Filomena Puntillo, Nicola Brienza
Is interleukin-8 a true predictor of pediatric acute respiratory distress syndrome outcomes? Beware of potential confounders
Sébastien Redant, François Angoulvant, Oceane Barbance, David De Bels, Andrea Gallerani, Rachid Attou, Kianoush Kashani, Patrick M. Honore
Alterations of the iNKT cell compartment in brain-injured patients
Allan Patinec, Jézabel Rocher, Mickael Vourc’h, Antoine Roquilly, Karim Asehnoune, Jacques Le Pendu
Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study
Michael G. S. Shashaty, John P. Reilly, Hilary E. Faust, Caitlin M. Forker, Caroline A. G. Ittner, Peggy X. Zhang, Meghan J. Hotz, David Fitzgerald, Wei Yang, Brian J. Anderson, Daniel N. Holena, Paul N. Lanken, Jason D. Christie, Nuala J. Meyer, Nilam S. Mangalmurti
Adipose tissue protects against sepsis-induced muscle weakness in mice: from lipolysis to ketones
Chloë Goossens, Ruben Weckx, Sarah Derde, Thomas Dufour, Sarah Vander Perre, Lies Pauwels, Steven E. Thiessen, Paul P. Van Veldhoven, Greet Van den Berghe, Lies Langouche
Pre-hospital plasma transfusion: a valuable coagulation support or an expensive fluid therapy?
Christian Fenger-Eriksen, Dietmar Fries, Jean-Stephane David, Pierre Bouzat, Marcus Daniel Lance, Oliver Grottke, Donat R. Spahn, Herbert Schoechl, Marc Maegele
The hospital frailty risk score is of limited value in intensive care unit patients
Raphael Romano Bruno, Bernhard Wernly, Hans Flaatten, Fabian Schölzel, Malte Kelm, Christian Jung
Adsorption and caspofungin dosing during continuous renal replacement therapy
Patrick M. Honore, David De Bels, Rachid Attou, Sebastien Redant, Andrea Gallerani, Kianoush Kashani
Trends in sepsis mortality over time in randomised sepsis trials: a systematic literature review and meta-analysis of mortality in the control arm, 2002–2016
Robert Luhr, Yang Cao, Bo Söderquist, Sara Cajander
Need for expanded Candida Score for empiric antifungal use in medically critically ill patients?
Melanie E. Laine, Alexander H. Flannery, Breanna Moody, Melissa L. Thompson Bastin
ECCCOing the call for emergency and critical care training in low middle-income countries
B. Jason Brotherton, Pete Halestrap, Evelyn Mbugua, Hannah Gitura, David Aliba, Jonathan E. Matson, Burton W. Lee
Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients
Candelaria de Haro, Rudys Magrans, Josefina López-Aguilar, Jaume Montanyà, Enrico Lena, Carles Subirà, Sol Fernandez-Gonzalo, Gemma Gomà, Rafael Fernández, Guillermo M. Albaiceta, Yoanna Skrobik, Umberto Lucangelo, Gastón Murias, Ana Ochagavia, Robert M. Kacmarek, Montserrat Rue, Lluís Blanch, Candelaria de Haro, Josefina López-Aguilar, Rudys Magrans, Sol Fernández-Gonzalo, Gemma Gomà, Encarna Chacón, Anna Estruga, Ana Ochagavia, Lluís Blanch, Jaume Montanya, Bernat Sales, Enrico Lena, Umberto Lucangelo, Rafael Fernández, Carles Subirà, Guillermo M. Albaiceta, Enrique Fernández-Mondejar, Gastón Murias, Robert M. Kacmarek
Neurological prognostication after cardiac arrest: how the “Best CPC” project would overcome selection biases
Marine Paul, Stéphane Legriel
Multimorbidity states associated with higher mortality rates in organ dysfunction and sepsis: a data-driven analysis in critical care
Zsolt Zador, Alexander Landry, Michael D. Cusimano, Nophar Geifman
Population pharmacokinetics of intravenous sufentanil in critically ill patients supported with extracorporeal membrane oxygenation therapy
Jongsung Hahn, Seungwon Yang, Kyoung Lok Min, Dasohm Kim, Byung Hak Jin, Changhun Park, Min Soo Park, Jin Wi, Min Jung Chang
Influence of contrast media on renal function and outcomes in patients with sepsis-associated acute kidney injury: a propensity-matched cohort study
Yuya Goto, Kansuke Koyama, Shinshu Katayama, Ken Tonai, Jun Shima, Toshitaka Koinuma, Shin Nunomiya
Health inequities in the diagnosis and outcome of sepsis in Argentina: a prospective cohort study
Elisa Estenssoro, Cecilia I. Loudet, Vanina S. K. Edul, Javier Osatnik, Fernando G. Ríos, Daniela N. Vásquez, Mario O. Pozo, Bernardo Lattanzio, Fernando Pálizas, Francisco Klein, Damián Piezny, Paolo N. Rubatto Birri, Graciela Tuhay, Anatilde Díaz, Analía Santamaría, Graciela Zakalik, Arnaldo Dubin, Carolina Enrico, Mariel Romitelli, Mariel A. García, José Celia, Leandro Machuca, Fernando Pálizas Jr, Mario Pozo, Bernardo Latanzio, Emanuel Valgolio, Mario Kenar, Carlos Sosa, Sergio Sarquis, Graciela Tuhay, Francisco Klein, Ariel Sosa, Daniel Ivulich, Luciana Bianchi, Enrique Correger, Carla Groer, Victoria Arrosagaray, Graciela Cueto, Carlos Cozzani, Gustavo Badariotti, Bernardo de Diego, Daniela N. Vazquez, Gustavo Plotnikov, Analía Santa-María, Mariana Bertes, Alejandro Gomez, María S. Santagiuliana, Margarita Tavela, Pierina Bachetti, Célica Irrazabal, Alejandro Risso-Vazquez, Paolo N. Rubatto-Birri, Gabriel Olarte, Veronica M. Cannatelli, Anatilde Díaz, Analía García, Estefanía Minoldo, Cayetano Galletti, Esteban Payer, Marcelo Avilez, Silvio E. Lazzeri, Luis A. Huespe, Lorena A. Parra, Fernando Kurban, Carlos A. Pellegrini, Adrian A. Martin, Graciela Zakalik, Magalí Sanchez, Natalia Barreto, Alfredo E. Carreras, Joahana Bastias, Julián Ivacachi, María L. Campassi, Fabio G. Repetto, María G. Saenz, Cecilia Marchena, María R. Marino, Gerardo Ezcurra, Sebastián Caravaggio, María A. García, Ana M. Mazzola, Analía Piernatei, Estela Molinas, Mauro Iadanza, Mario A. Traba, Leda F. Bacci, Adriana Fernandez, Damián Piezny, Constanza Arias, Gustavo Chaparro, Graciela C. Lopez, Agustín Fernández, Catalina Reyes-Najera, Adriana Baldiviezo, Alejandra Flores, Alejandro Risso-Vazquez, Irma Moyano, Mónica Quinteros, Laura Budrovich, Lilen Corzo, Sebastián A. Amieva, Melisa Ré, Nicolás Rocchetti, Juan C. Pendino, Lisandro Bettini, Lionel Talamonti, Gustavo Izaguirre, German Schmukler, Ignacio Sabbag, Tomas F. Diez, Laura Bergallo, Cecilia González, Carlos Lovezio, Daniel Duarte, Romina Nicastro, Fernando Bertoletti, Esteban Milioto
Comparative efficacy of linezolid and vancomycin for endotracheal tube MRSA biofilms from ICU patients
Laia Fernández-Barat, Ana Motos, Mauro Panigada, Francisco Álvarez-Lerma, Lucía Viña, Ruben Lopez-Aladid, Adrian Ceccato, Gianluigi Li Bassi, David P. Nicolau, Yuli Lopez, Laura Muñoz, Laura Guerrero, Dolors Soy, Trinidad Israel, Pedro Castro, Antoni Torres
Decrease of the plasmatic endocan cleavage ratio is associated with the hyperinflammatory phenotype of acute respiratory distress syndrome
Alexandre Gaudet, Erika Parmentier, Nathalie De Freitas Caires, Lucie Portier, Sylvain Dubucquoi, Julien Poissy, Thibault Duburcq, Maxence Hureau, Philippe Lassalle, Daniel Mathieu
Lack of clinically relevant correlation between subjective and objective cognitive function in ICU survivors: a prospective 12-month follow-up study
Emily Brück, Jacob W. Larsson, Julie Lasselin, Matteo Bottai, Tatja Hirvikoski, Eva Sundman, Michael Eberhardson, Peter Sackey, Peder S. Olofsson
Interaction between low tidal volume ventilation strategy and severity of acute respiratory distress syndrome: a retrospective cohort study
Yanfei Shen, Guolong Cai, Shijin Gong, Lei Dong, Jing Yan, Wanru Cai
Correction to: The early identification of disease progression in patients with suspected infection presenting to the emergency department: a multi-centre derivation and validation study
Kordo Saeed, Darius Cameron Wilson, Frank Bloos, Philipp Schuetz, Yuri van der Does, Olle Melander, Pierre Hausfater, Jacopo M. Legramante, Yann-Erick Claessens, Deveendra Amin, Mari Rosenqvist, Graham White, Beat Mueller, Maarten Limper, Carlota Clemente Callejo, Antonella Brandi, Marc-Alexis Macchi, Nicholas Cortes, Alexander Kutz, Peter Patka, María Cecilia Yañez, Sergio Bernardini, Nathalie Beau, Matthew Dryden, Eric C. M. van Gorp, Marilena Minieri, Louisa Chan, Pleunie P. M. Rood, Juan Gonzalez del Castillo
Recovery from acute kidney injury as a potent predictor of survival and good neurological outcome at discharge after out-of-hospital cardiac arrest
Yoo Seok Park, Yoon Hee Choi, Je Hyeok Oh, In Soo Cho, Kyoung-Chul Cha, Byung-Sun Choi, Je Sung You
Feasibility of myocardial perfusion assessment with contrast echocardiography: can it improve recognition of significant coronary artery disease in the ICU?
Sam Orde, Michel Slama, Faraz Pathan, Stephen Huang, Anthony Mclean
Influenza virus-related critical illness: pathophysiology and epidemiology
Andre C. Kalil, Paul G. Thomas
Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation
Joseph A. Hippensteel, Ryo Uchimido, Patrick D. Tyler, Ryan C. Burke, Xiaorui Han, Fuming Zhang, Sarah A. McMurtry, James F. Colbert, Christopher J. Lindsell, Derek C. Angus, John A. Kellum, Donald M. Yealy, Robert J. Linhardt, Nathan I. Shapiro, Eric P. Schmidt
Association of sublingual microcirculation parameters and endothelial glycocalyx dimensions in resuscitated sepsis
Alexandros Rovas, Laura Mareen Seidel, Hans Vink, Timo Pohlkötter, Hermann Pavenstädt, Christian Ertmer, Michael Hessler, Philipp Kümpers
Abdominal functional electrical stimulation to assist ventilator weaning in critical illness: a double-blinded, randomised, sham-controlled pilot study
Euan J. McCaughey, Annemijn H. Jonkman, Claire L. Boswell-Ruys, Rachel A. McBain, Elizabeth A. Bye, Anna L. Hudson, David W. Collins, Leo M. A. Heunks, Angus J. McLachlan, Simon C. Gandevia, Jane E. Butler
Liberal versus restrictive red blood cell transfusion strategy in sepsis or septic shock: a systematic review and meta-analysis of randomized trials
Yohei Hirano, Yukari Miyoshi, Yutaka Kondo, Ken Okamoto, Hiroshi Tanaka
Sex-specific differences in survival after out-of-hospital cardiac arrest: a nationwide, population-based observational study
Yoshikazu Goto, Akira Funada, Tetsuo Maeda, Hirofumi Okada, Yumiko Goto
Functional hemodynamic tests: a systematic review and a metanalysis on the reliability of the end-expiratory occlusion test and of the mini-fluid challenge in predicting fluid responsiveness
Antonio Messina, Antonio Dell’Anna, Marta Baggiani, Flavia Torrini, Gian Marco Maresca, Victoria Bennett, Laura Saderi, Giovanni Sotgiu, Massimo Antonelli, Maurizio Cecconi
Vitamin C administration in the critically ill: a summary of recent meta-analyses
Anitra C. Carr
Limb ischemia in peripheral veno-arterial extracorporeal membrane oxygenation: a narrative review of incidence, prevention, monitoring, and treatment
Eleonora Bonicolini, Gennaro Martucci, Jorik Simons, Giuseppe M. Raffa, Cristina Spina, Valeria Lo Coco, Antonio Arcadipane, Michele Pilato, Roberto Lorusso
Vitamin A deficiency in critically ill children with sepsis
Xuepeng Zhang, Kaiying Yang, Linwen Chen, Xuelian Liao, Liping Deng, Siyuan Chen, Yi Ji
Mottling reduction in the early phases of profound septic shock
Daniel Taylor, Duncan Wyncoll
Functions and regulation of lipocalin-2 in gut-origin sepsis: a narrative review
Fanglin Lu, Kei Inoue, Jungo Kato, Shizuka Minamishima, Hiroshi Morisaki
The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT
Greet De Vlieger, Ilse Vanhorebeek, Pieter J. Wouters, Inge Derese, Michael P. Casaer, Yves Debaveye, Greet Hermans, Philippe Meersseman, Holger J. Møller, Greet Van den Berghe, Catherine Ingels
Combined assessment of ΔPCT and ΔCRP could increase the ability to differentiate candidemia from bacteremia
Qin Wu, Hao Yang, Yan Kang
Is this patient really “(un)stable”? How to describe cardiovascular dynamics in critically ill patients
Jean-Louis Vincent, Maurizio Cecconi, Bernd Saugel
Harmful effects of mechanical ventilation on neurocognitive functions
Federico Bilotta, Giovanni Giordano, Paola Giuseppina Sergi, Francesco Pugliese
The end-expiratory occlusion test: please, let me hold your breath!
Francesco Gavelli, Jean-Louis Teboul, Xavier Monnet
Veno-venous ECMO indications: more than respiratory support
Aaron Blandino Ortiz, David Cabestrero Alonso, Raúl De Pablo Sánchez
Screening for posttraumatic stress disorder in ARDS survivors: validation of the Impact of Event Scale-6 (IES-6)
Megan M. Hosey, Jeannie-Marie S. Leoutsakos, Ximin Li, Victor D. Dinglas, O. Joseph Bienvenu, Ann M. Parker, Ramona O. Hopkins, Dale M. Needham, Karin J. Neufeld
Interventions to prevent iatrogenic anemia: a Laboratory Medicine Best Practices systematic review
Nedra S. Whitehead, Laurina O. Williams, Sreelatha Meleth, Sara M. Kennedy, Nneka Ubaka-Blackmoore, Sharon M. Geaghan, James H. Nichols, Patrick Carroll, Michael T. McEvoy, Julie Gayken, Dennis J. Ernst, Christine Litwin, Paul Epner, Jennifer Taylor, Mark L. Graber
A deep learning model for real-time mortality prediction in critically ill children
Soo Yeon Kim, Saehoon Kim, Joongbum Cho, Young Suh Kim, In Suk Sol, Youngchul Sung, Inhyeok Cho, Minseop Park, Haerin Jang, Yoon Hee Kim, Kyung Won Kim, Myung Hyun Sohn
Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential
Takashi Ito, Jecko Thachil, Hidesaku Asakura, Jerrold H. Levy, Toshiaki Iba
Capillary refill time variation induced by passive leg raising predicts capillary refill time response to volume expansion
Matthias Jacquet-Lagrèze, Nourredine Bouhamri, Philippe Portran, Rémi Schweizer, Florent Baudin, Marc Lilot, William Fornier, Jean-Luc Fellahi
Machine learning versus physicians’ prediction of acute kidney injury in critically ill adults: a prospective evaluation of the AKIpredictor
Marine Flechet, Stefano Falini, Claudia Bonetti, Fabian Güiza, Miet Schetz, Greet Van den Berghe, Geert Meyfroidt
Biomarker profiles of coagulopathy and alveolar epithelial injury in acute respiratory distress syndrome with idiopathic/immune-related disease or common direct risk factors
Kansuke Koyama, Shinshu Katayama, Ken Tonai, Jun Shima, Toshitaka Koinuma, Shin Nunomiya
Use of machine learning to analyse routinely collected intensive care unit data: a systematic review
Duncan Shillan, Jonathan A. C. Sterne, Alan Champneys, Ben Gibbison
Effect of different methods of cooling for targeted temperature management on outcome after cardiac arrest: a systematic review and meta-analysis
Lorenzo Calabró, Wulfran Bougouin, Alain Cariou, Chiara De Fazio, Markus Skrifvars, Eldar Soreide, Jacques Creteur, Hans Kirkegaard, Stéphane Legriel, Jean-Baptiste Lascarrou, Bruno Megarbane, Nicolas Deye, Fabio Silvio Taccone
Outcomes of hospitalized hematologic oncology patients receiving rapid response system activation for acute deterioration
Benjamin Gershkovich, Shannon M. Fernando, Brent Herritt, Lana A. Castellucci, Bram Rochwerg, Laveena Munshi, Sangeeta Mehta, Andrew J. E. Seely, Daniel I. McIsaac, Alexandre Tran, Peter M. Reardon, Peter Tanuseputro, Kwadwo Kyeremanteng
Quantitative lung ultrasonography: a putative new algorithm for automatic detection and quantification of B-lines
Claudia Brusasco, Gregorio Santori, Elisa Bruzzo, Rosella Trò, Chiara Robba, Guido Tavazzi, Fabio Guarracino, Francesco Forfori, Patrizia Boccacci, Francesco Corradi
Icatibant, another piece of the therapeutic puzzle regarding hemodynamic side effects of angiotensin-converting enzyme inhibitors
Patrick M. Honore, David De Bels, Leonel Barreto Gutierrez, Sebastien Redant, Andrea Gallerani, Willem Boer
Interleukin-26 is overexpressed in human sepsis and contributes to inflammation, organ injury, and mortality in murine sepsis
Hongmei Tu, Xiaofei Lai, Jiaxi Li, Lili Huang, Yi Liu, Ju Cao
Effect of dementia on the incidence, short-term outcomes, and resource utilization of invasive mechanical ventilation in the elderly: a nationwide population-based study
Carmen Bouza, Gonzalo Martínez-Alés, Teresa López-Cuadrado
Exploring the microvascular impact of red blood cell transfusion in intensive care unit patients
Geoffroy Hariri, Simon Bourcier, Zora Marjanovic, Jérémie Joffre, Jérémie Lemarié, Jean-Rémi Lavillegrand, Dominique Charue, Thomas Duflot, Naïke Bigé, Jean-Luc Baudel, Eric Maury, Mohamad Mohty, Bertrand Guidet, Jeremy Bellien, Olivier Blanc-Brude, Hafid Ait-Oufella
Impact of post-sepsis cardiovascular complications on mortality in sepsis survivors: a population-based study
Meng-Huan Wu, Po-Yang Tsou, Yu-Hsun Wang, Meng-tse Gabriel Lee, Christin Chih Ting Chao, Wan-Chien Lee, Si-Huei Lee, Jiun-Ruey Hu, Jiunn-Yih Wu, Shy-Shin Chang, Chien-Chang Lee
Confounding factors for the effect of misdiagnosis of site of infection on in-hospital mortality
Kei Suzuki, Shinichiro Ohshimo, Nobuaki Shime
Feedback function for capillary refilling time measurement device
Masayoshi Shinozaki, Taka-aki Nakada, Rui Kawaguchi, Yuichiro Yoshimura, Toshiya Nakaguchi, Hideaki Haneishi, Shigeto Oda
Endocan is a reliable biomarker during continuous renal replacement therapy
Maxence Hureau, Alexandre Gaudet, Nathalie De Freitas Caires, Erika Parmentier, Julien Poissy, Thibault Duburcq, Philippe Lassalle, Daniel Mathieu
Endotoxin removal by polymyxin B: is it a question of dose or duration or both?
Patrick M. Honore, David De Bels, Leonel Barreto Gutierrez, Sebastien Redant, Andrea Gallerani, Willem Boer
The association between premorbid beta blocker exposure and mortality in sepsis—a systematic review
Kaiquan Tan, Martin Harazim, Benjamin Tang, Anthony Mclean, Marek Nalos
Time-based capnography detects ineffective triggering in mechanically ventilated children
Robert G. T. Blokpoel, Alette A. Koopman, Jefta van Dijk, Frans H. C. de Jongh, Johannes G. M. Burgerhof, Martin C. J. Kneyber
A multicenter RCT of noninvasive ventilation in pneumonia-induced early mild acute respiratory distress syndrome
Hangyong He, Bing Sun, Lirong Liang, Yanming Li, He Wang, Luqing Wei, Guofeng Li, Shuliang Guo, Jun Duan, Yuping Li, Ying Zhou, Yusheng Chen, Hongru Li, Jingping Yang, Xiyuan Xu, Liqiang Song, Jie Chen, Yong Bao, Feng Chen, Ping Wang, Lixi Ji, Yongxiang Zhang, Yanyan Ding, Liangan Chen, Ying Wang, Lan Yang, Tian Yang, Heng Weng, Hongyan Li, Daoxin Wang, Jin Tong, Yongchang Sun, Ran Li, Faguang Jin, Chunmei Li, Bei He, Lina Sun, Changzheng Wang, Mingdong Hu, Xiaohong Yang, Qin Luo, Jin Zhang, Hai Tan, Chen Wang, Hangyong He, Bing Sun, Lirong Liang, Yanming Li, He Wang, Luqing Wei, Guofeng Li, Bin Liu, Shuliang Guo, Jun Duan, Yuping Li, Ying Zhou, Yusheng Chen, Hongru Li, Rujun Hong, Xiujuan Yao, Fengfeng Lu, Jingping Yang, Xiyuan Xu, Hui Wang, Ling Wang, Hongjun Tian, Liqiang Song, Jie Chen, Yunfu Wu, Yong Bao, Feng Chen, Ping Wang, Lixi Ji, Xiaofang Huang, Min Sun, Yongxiang Zhang, Yanyan Ding, Liangan Chen, Ying Wang, Zhixin Liang, Lan Yang, Tian Yang, Heng Weng, Hongyan Li, Xu Lin, Daoxin Wang, Jin Tong, Wang Deng, Yongchang Sun, Ran Li, Jie Xu, Faguang Jin, Yandong Nan, Chunmei Li, Bei He, Ning Shen, Lina Sun, Changzheng Wang, Mingdong Hu, Xiaohong Yang, Qin Luo, Mei Li, Jin Zhang, Hai Tan, Chen Wang
Co-administration of iloprost and eptifibatide in septic shock (CO-ILEPSS)—a randomised, controlled, double-blind investigator-initiated trial investigating safety and efficacy
Rasmus Ehrenfried Berthelsen, Sisse Rye Ostrowski, Morten Heiberg Bestle, Per Ingemar Johansson
Recombinant human soluble thrombomodulin in patients with sepsis-associated coagulopathy (SCARLET): an updated meta-analysis
Kazuma Yamakawa, Jerrold H. Levy, Toshiaki Iba
Host susceptibility to severe influenza A virus infection
Sara Clohisey, John Kenneth Baillie
Sevoflurane and nephrogenic diabetes insipidus on the rise: copeptin to the rescue?
Patrick M. Honore, David De Bels, Leonel Barreto Gutierrez, Sebastien Redant, Andrea Gallerani, Willem Boer
Neuromuscular blocking agents for acute respiratory distress syndrome: how did we get conflicting results?
Heather Torbic, Sudhir Krishnan, Abhijit Duggal
Center effect in intubation risk in critically ill immunocompromised patients with acute hypoxemic respiratory failure
Guillaume Dumas, Alexandre Demoule, Djamel Mokart, Virginie Lemiale, Saad Nseir, Laurent Argaud, Frédéric Pène, Loay Kontar, Fabrice Bruneel, Kada Klouche, François Barbier, Jean Reignier, Annabelle Stoclin, Guillaume Louis, Jean-Michel Constantin, Florent Wallet, Achille Kouatchet, Vincent Peigne, Pierre Perez, Christophe Girault, Samir Jaber, Yves Cohen, Martine Nyunga, Nicolas Terzi, Lila Bouadma, Christine Lebert, Alexandre Lautrette, Naike Bigé, Jean-Herlé Raphalen, Laurent Papazian, Dominique Benoit, Michael Darmon, Sylvie Chevret, Elie Azoulay
Impact of species and antibiotic therapy of enterococcal peritonitis on 30-day mortality in critical care—an analysis of the OUTCOMEREA database
Anne-Cécile Morvan, Baptiste Hengy, Maïté Garrouste-Orgeas, Stéphane Ruckly, Jean-Marie Forel, Laurent Argaud, Thomas Rimmelé, Jean-Pierre Bedos, Elie Azoulay, Claire Dupuis, Bruno Mourvillier, Carole Schwebel, Jean-François Timsit, Jean-François Timsit, Elie Azoulay, Maïté Garrouste-Orgeas, Jean-Ralph Zahar, Bruno Mourvillier, Michael Darmon, Christophe Clec’h, Corinne Alberti, Stephane Ruckly, Sébastien Bailly, Aurélien Vannieuwenhuyze, Romain Hernu, Christophe Adrie, Carole Agasse, Bernard Allaouchiche, Olivier Andremont, Pascal Andreu, Laurent Argaud, Claire Ara-Somohano, Elie Azoulay, Francois Barbier, Déborah Boyer, Jean-Pierre Bedos, Thomas Baudry, Jérome Bedel, Julien Bohé, Lila Bouadma, Jeremy Bourenne, Noel Brule, Cédric Brétonnière, Frank Chemouni, Christine Cheval, Julien Carvelli, Elisabeth Coupez, Martin Cour, Claire Dupuis, Etienne de Montmollin, Loa Dopeux, Anne-Sylvie Dumenil, Jean-Marc Forel, Marc Gainnier, Charlotte Garret, Dany Goldgran-Tonedano, Steven Grangé, Antoine Gros, Hédia Hammed, Akim Haouache, Romain Hernu, Tarik Hissem, Vivien Hong Tuan Ha, Sébastien Jochmans, Jean-Baptiste Joffredo, Hatem Kallel, Guillaume Lacave, Virgine Laurent, Alexandre Lautrette, Clément Le bihan Eric Magalhaes, Virgine Lemiale, Guillaume Marcotte, Jordane Lebut, Maxime Lugosi, Sibylle Merceron, Benoît Misset, Mathild Neuville, Laurent Nicolet, Johanna Oziel, Laurent Papazian, Juliette Patrier, Benjamin Planquette, Aguila Radjou, Marie Simon, Romain Sonneville, Jean Reignier, Bertrand Souweine, Carole Schwebel, Shidasp Siami, Romain Sonneville, Nicolas Terzi, Gilles Troché, Marie Thuong, Guillaume Thierry, Marion Venot, Sondes Yaacoubi, Olivier Zambon, Julien Fournier, Stéphanie Bagur, Mireille Adda, Vanessa Vindrieux, Sylvie de la Salle, Pauline Enguerrand, Vincent Gobert, Stéphane Guessens, Helene Merle, Nadira Kaddour, Boris Berthe, Samir Bekkhouche, Kaouttar Mellouk, Mélaine Lebrazic, Carole Ouisse, Diane Maugars, Christelle Aparicio, Igor Theodose, Manal Nouacer, Veronique Deiler, Fariza Lamara, Myriam Moussa, Atika Mouaci, Nassima Viguier
Differential contractile response of critically ill patients to neuromuscular electrical stimulation
Julius J. Grunow, Moritz Goll, Niklas M. Carbon, Max E. Liebl, Steffen Weber-Carstens, Tobias Wollersheim
Transfusion practice in the non-bleeding critically ill: an international online survey—the TRACE survey
Sanne de Bruin, Thomas W. L. Scheeren, Jan Bakker, Robin van Bruggen, Alexander P. J. Vlaar, Massimo Antonelli, Cecile Aubron, Maurizio Cecconi, Joanna C. Dionne, Jacques Duranteau, Nicole P. Juffermans, Dirk de Korte, Jens Meier, Gavin Murphy, Simon Oczkowski, Anders Perner, Timothy Walsh
SEA-mulation: training for technical treatment related to emergency situations in maritime environment
Brice Loddé, Gael-Emgan Querellou, Alexandre Morel, Erwan L’Her
Relationship of mottling score, skin microcirculatory perfusion indices and biomarkers of endothelial dysfunction in patients with septic shock: an observational study
Sigita Kazune, Anastasija Caica, Karina Volceka, Olegs Suba, Uldis Rubins, Andris Grabovskis
Comparison of echocardiographic indices of right ventricular systolic function and ejection fraction obtained with continuous thermodilution in critically ill patients
Romain Barthélémy, Xavier Roy, Tujia Javanainen, Alexandre Mebazaa, Benjamin Glenn Chousterman
What is the best core measure after critical illness when the IES-R is no longer accessible for new researchers?
Reba Umberger
Candida bloodstream infection under veno-arterial ECMO therapy
Quentin de Roux, Françoise Botterel, Raphaël Lepeule, Fabio Silvio Taccone, Olivier Langeron, Nicolas Mongardon
Letter by Neugebauer et al. regarding article “Hypothermia after decompressive hemicraniectomy in treatment of malignant middle cerebral artery stroke: comment on the randomized clinical trial”
Hermann Neugebauer, Hauke Schneider, Rainer Kollmar
How I wean patients from veno-venous extra-corporeal membrane oxygenation
Francesco Vasques, Federica Romitti, Luciano Gattinoni, Luigi Camporota
Hemoadsorption with CytoSorb shows a decreased observed versus expected 28-day all-cause mortality in ICU patients with septic shock: a propensity-score-weighted retrospective study
Willem Pieter Brouwer, Servet Duran, Martijn Kuijper, Can Ince
Metabolic support in the critically ill: a consensus of 19
Jan Wernerman, Kenneth B. Christopher, Djillali Annane, Michael P. Casaer, Craig M. Coopersmith, Adam M. Deane, Elisabeth De Waele, Gunnar Elke, Carole Ichai, Constantine J. Karvellas, Stephen A. McClave, Heleen M. Oudemans-van Straaten, Olav Rooyackers, Renee D. Stapleton, Jukka Takala, Arthur R. H. van Zanten, Paul E. Wischmeyer, Jean-Charles Preiser, Jean-Louis Vincent
Preoxygenation before intubation in adult patients with acute hypoxemic respiratory failure: a network meta-analysis of randomized trials
Ka Man Fong, Shek Yin Au, George Wing Yiu Ng
Epinephrine, inodilator, or no inotrope in venoarterial extracorporeal membrane oxygenation implantation: a single-center experience
Viviane Zotzmann, Jonathan Rilinger, Corinna N. Lang, Klaus Kaier, Christoph Benk, Daniel Duerschmied, Paul M. Biever, Christoph Bode, Tobias Wengenmayer, Dawid L. Staudacher
Myocardial ischemia during ventilator weaning: a prospective multicenter cohort study
Alexandre Bedet, Françoise Tomberli, Gwenael Prat, Pierre Bailly, Achille Kouatchet, Sater Mortaza, Emmanuel Vivier, Sylvene Rosselli, Larissa Lipskaia, Guillaume Carteaux, Keyvan Razazi, Armand Mekontso Dessap
Correction to: Procalcitonin levels in candidemia versus bacteremia: a systematic review
Andrea Cortegiani, Giovanni Misseri, Mariachiara Ippolito, Matteo Bassetti, Antonino Giarratano, Ignacio Martin-Loeches, Sharon Einav
Early prognostication of neurological outcome by heart rate variability in adult patients with out-of-hospital sudden cardiac arrest
Hiroshi Endoh, Natuo Kamimura, Hiroyuki Honda, Masakazu Nitta
Rescue fecal microbiota transplantation for antibiotic-associated diarrhea in critically ill patients
Min Dai, Yafei Liu, Wei Chen, Heena Buch, Yi Shan, Liuhui Chang, Yong Bai, Chen Shen, Xiaoyin Zhang, Yufeng Huo, Dian Huang, Zhou Yang, Zhihang Hu, Xuwei He, Junyu Pan, Lili Hu, Xinfang Pan, Xiangtao Wu, Bin Deng, Zhifeng Li, Bota Cui, Faming Zhang
Correction to: Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials
Luca Cabrini, Giovanni Landoni, Martina Baiardo Redaelli, Omar Saleh, Carmine D. Votta, Evgeny Fominskiy, Alessandro Putzu, Cézar Daniel Snak de Souza, Massimo Antonelli, Rinaldo Bellomo, Paolo Pelosi, Alberto Zangrillo
SSEP retains its value as predictor of poor outcome following cardiac arrest in the era of therapeutic hypothermia
Ted L. Rothstein
Obesity inducing acute respiratory distress syndrome: we should choose the right population!
Patrick M. Honore, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani, David De Bels
The interactive effects of input and output on managing fluid balance in patients with acute kidney injury requiring continuous renal replacement therapy
Jong Hyun Jhee, Hye Ah Lee, Seonmi Kim, Youn Kyung Kee, Ji Eun Lee, Shina Lee, Seung-Jung Kim, Duk-Hee Kang, Kyu Bok Choi, Hyung Jung Oh, Dong-Ryeol Ryu
Clinical significance of lymphocytopenia in patients hospitalized with pneumonia caused by influenza virus
Valeria Bellelli, Gabriella d’Ettorre, Luigi Celani, Cristian Borrazzo, Giancarlo Ceccarelli, Mario Venditti
How levosimendan can improve renal function?
Patrick M. Honore, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani, David De Bels
Positive cultures and clinical outcomes in septic patients: be aware of the influence from patient selection and the in-hospital confounders
Romain Jouffroy, Benoît Vivien
Prognostic performance of age-adapted SOFA and qSOFA in septic children
Xuepeng Zhang, Xiying Gui, Kaiying Yang, Siyuan Chen, Yi Ji
Correlation between end-tidal carbon dioxide and the degree of compression of heart cavities measured by transthoracic echocardiography during cardiopulmonary resuscitation for out-of-hospital cardiac arrest
Roman Skulec, Petr Vojtisek, Vladimir Cerny
Biomarkers and clinical scores to identify patient populations at risk of delayed antibiotic administration or intensive care admission
Juan Gonzalez del Castillo, Darius Cameron Wilson, Carlota Clemente-Callejo, Francisco Román, Ignasi Bardés-Robles, Inmaculada Jiménez, Eva Orviz, Macarena Dastis-Arias, Begoña Espinosa, Fernando Tornero-Romero, Jordi Giol-Amich, Veronica González, Ferran Llopis-Roca, Joan Ramon Pérez-Mas, Elena Fuentes-González, Concepción Martínez-Muñoz, Elena Martínez-Beloqui, Francisco Javier Martín-Sánchez, Paula Mostaza Gallar, Luis Picazo García, Alejandro Malo de Molina Herrera
Comment upon “Time to epinephrine treatment is associated with the risk of mortality in children who achieve sustained ROSC after traumatic out-of-hospital cardiac arrest”
Benjamin Post, Dominic Peter Douglas Nielsen, Anil Visram
Preparing intensive care for the next pandemic influenza
Taylor Kain, Robert Fowler
Adaptive mechanical ventilation with automated minimization of mechanical power—a pilot randomized cross-over study
Tobias Becher, Anna Adelmeier, Inéz Frerichs, Norbert Weiler, Dirk Schädler
What should be the best dialysis catheter lock in critically ill patients?
Patrick M. Honore, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani, David De Bels
The place of dexmedetomidine light sedation in patients with acute brain injury
Simone Carelli, Gennaro De Pascale, Nicoletta Filetici, Maria Grazia Bocci, Gian Marco Maresca, Salvatore Lucio Cutuli, Cecilia Maria Pizzo, Giuseppe Bello, Luca Montini, Anselmo Caricato, Giorgio Conti, Massimo Antonelli
NT-proBNP levels might predict outcomes in severe sepsis, but renal function cannot be ignored
Jiarong Ye, Qianrong Liang, Xiaotu Xi
Hemoadsorption efficacy for uncomplicated high-risk cardiac surgery
Sébastien Redant, Matthieu Legrand, Yael Langman, Alejandra Garcia Aguilar, François Angoulvant, Keitiane Kaefer, David De Bels, Rachid Attou, Kianoush Kashani, Patrick M. Honore
High-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients after planned extubation
Meng-Si Luo, Guan-Jiang Huang, Lun Wu
Caution should be taken when using electronic health record database
Lina Wang, Xiaoming Wu
A novel non-invasive method to detect excessively high respiratory effort and dynamic transpulmonary driving pressure during mechanical ventilation
Michele Bertoni, Irene Telias, Martin Urner, Michael Long, Lorenzo Del Sorbo, Eddy Fan, Christer Sinderby, Jennifer Beck, Ling Liu, Haibo Qiu, Jenna Wong, Arthur S. Slutsky, Niall D. Ferguson, Laurent J. Brochard, Ewan C. Goligher
Effect of tranexamic acid on mortality in patients with haemoptysis: a nationwide study
Takahiro Kinoshita, Hiroyuki Ohbe, Hiroki Matsui, Kiyohide Fushimi, Hiroshi Ogura, Hideo Yasunaga
Low-flow assessment of current ECMO/ECCO2R rotary blood pumps and the potential effect on hemocompatibility
Sascha Gross-Hardt, Felix Hesselmann, Jutta Arens, Ulrich Steinseifer, Leen Vercaemst, Wolfram Windisch, Daniel Brodie, Christian Karagiannidis
Effects of a swallowing and oral care intervention for patients following endotracheal extubation: a pre- and post-intervention study
Chung-Pei Wu, Yu-Juan Xu, Tyng-Guey Wang, Shih-Chi Ku, Ding-Cheng Chan, Jang-Jaer Lee, Yu-Chung Wei, Tzu-Yu Hsiao, Cheryl Chia-Hui Chen
Early lactate measurement is associated with better outcomes in septic patients with an elevated serum lactate level
Hui Chen, Chenyan Zhao, Yao Wei, Jun Jin
Long-term cognitive impairment after acute respiratory distress syndrome: a review of clinical impact and pathophysiological mechanisms
Cina Sasannejad, E. Wesley Ely, Shouri Lahiri
Exogenous vasopressin dose-dependently modulates gastric microcirculatory oxygenation in dogs via V1A receptor
Richard Truse, Steven Grewe, Anna Herminghaus, Jan Schulz, Andreas P. M. Weber, Tabea Mettler-Altmann, Inge Bauer, Olaf Picker, Christian Vollmer
Attainment of therapeutic vancomycin level within the first 24 h: Authors' response
João Pedro Baptista, Jason A. Roberts, Eduardo Sousa, Ricardo Freitas, Nuno Devesa, Jorge Pimentel
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis
McKenzie K. Hollen, Julie A. Stortz, Dijoia Darden, Marvin L. Dirain, Dina C. Nacionales, Russell B. Hawkins, Michael C. Cox, Maria-Cecilia Lopez, Jaimar C. Rincon, Ricardo Ungaro, Zhongkai Wang, Quran Wu, Babette Brumback, Marie-Pierre L. Gauthier, Michael Kladde, Christiaan Leeuwenburgh, Mark Segal, Azra Bihorac, Scott Brakenridge, Frederick A. Moore, Henry V. Baker, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron
Extracorporeal membrane oxygenation in Pneumocystis jirovecii pneumonia: outcome in HIV and non-HIV patients
Jonathan Rilinger, Dawid L. Staudacher, Siegbert Rieg, Daniel Duerschmied, Christoph Bode, Tobias Wengenmayer
Left ventricular wall findings in non-electrocardiography-gated contrast-enhanced computed tomography after extracorporeal cardiopulmonary resuscitation
Kazuhiro Sugiyama, Masamichi Takahashi, Kazuki Miyazaki, Takuto Ishida, Mioko Kobayashi, Yuichi Hamabe
Noninvasive ventilation in patients with acute respiratory distress syndrome
Kailei Du
A significant p value is not equivalent to the superiority of one test index over another
Qiaoying Ji, Weimin Li
Implementation of earlier antibiotic administration in patients with severe sepsis and septic shock in Japan: a descriptive analysis of a prospective observational study
Toshikazu Abe, Shigeki Kushimoto, Yasuharu Tokuda, Gary S. Phillips, Andrew Rhodes, Takehiro Sugiyama, Akira Komori, Hiroki Iriyama, Hiroshi Ogura, Seitaro Fujishima, Atsushi Shiraishi, Daizoh Saitoh, Toshihiko Mayumi, Toshio Naito, Kiyotsugu Takuma, Taka-aki Nakada, Yasukazu Shiino, Takehiko Tarui, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Yutaka Umemura, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-ichiro Shiraishi, Ryosuke Tsuruta, Akiyoshi Hagiwara, Kazuma Yamakawa, Tomohiko Masuno, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Masashi Ueyama, Satoshi Gando, Osamu Tasaki, Yasumitsu Mizobata, Hiraku Funakoshi, Toshiro Okuyama, Iwao Yamashita, Toshio Kanai, Yasuo Yamada, Mayuki Aibiki, Keiji Sato, Susumu Yamashita, Kenichi Yoshida, Shunji Kasaoka, Akihide Kon, Hiroshi Rinka, Hiroshi Kato, Hiroshi Okudera, Eichi Narimatsu, Toshifumi Fujiwara, Manabu Sugita, Yasuo Shichinohe, Hajime Nakae, Ryouji Iiduka, Mitsunobu Nakamura, Yuji Murata, Yoshitake Sato, Hiroyasu Ishikura, Yasuhiro Myojo, Yasuyuki Tsujita, Kosaku Kinoshita, Hiroyuki Yamaguchi, Toshihiro Sakurai, Satoru Miyatake, Takao Saotome, Susumu Yasuda, Toshikazu Abe, Hiroshi Ogura, Yutaka Umemura, Atsushi Shiraishi, Shigeki Kushimoto, Daizoh Saitoh, Seitaro Fujishima, Junichi Sasaki, Toshihiko Mayumi, Yasukazu Shiino, Taka-aki Nakada, Takehiko Tarui, Toru Hifumi, Yasuhiro Otomo, Joji Kotani, Yuichiro Sakamoto, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Kazuma Yamakawa, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Yasuaki Mizushima, Satoshi Gando
Translational medicine between human and veterinary emergency and critical care medicine: a story meant to have a happy ending
Nuno M. Félix, K. Gommeren, S. Boysen
The IES-R remains a core outcome measure for PTSD in critical illness survivorship research
Megan M. Hosey, O. Joseph Bienvenu, Victor D. Dinglas, Alison E. Turnbull, Ann M. Parker, Ramona O. Hopkins, Karin J. Neufeld, Dale M. Needham
Beneficial effects of early empirical administration of appropriate antimicrobials on survival and defervescence in adults with community-onset bacteremia
Ching-Chi Lee, Chung-Hsun Lee, Chao-Yung Yang, Chih-Chia Hsieh, Hung-Jen Tang, Wen-Chien Ko
Continual measurement of arterial dP/dtmax enables minimally invasive monitoring of left ventricular contractility in patients with acute heart failure
Petr Ostadal, Dagmar Vondrakova, Andreas Krüger, Marek Janotka, Jan Naar
Derivation and validation of an easy-to-compute trauma score that improves prognostication of mortality or the Trauma Rating Index in Age, Glasgow Coma Scale, Respiratory rate and Systolic blood pressure (TRIAGES) score
Atsushi Shiraishi, Yasuhiro Otomo, Shunsuke Yoshikawa, Koji Morishita, Ian Roberts, Hiroki Matsui
Why physiology will continue to guide the choice between balanced crystalloids and normal saline: a systematic review and meta-analysis
Charlotte L. Zwager, Pieter Roel Tuinman, Harm-Jan de Grooth, Jos Kooter, Hans Ket, Lucas M. Fleuren, Paul W. G. Elbers
Association between hospital mortality and inspiratory airway pressures in mechanically ventilated patients without acute respiratory distress syndrome: a prospective cohort study
Sarina K. Sahetya, Christopher Mallow, Jonathan E. Sevransky, Greg S. Martin, Timothy D. Girard, Roy G. Brower, William Checkley
Nutrition therapy and critical illness: practical guidance for the ICU, post-ICU, and long-term convalescence phases
Arthur Raymond Hubert van Zanten, Elisabeth De Waele, Paul Edmund Wischmeyer
Effects of inspiratory flow on lung stress, pendelluft, and ventilation heterogeneity in ARDS: a physiological study
Alessandro Santini, Tommaso Mauri, Francesca Dalla Corte, Elena Spinelli, Antonio Pesenti
Respective contribution of intensive care unit-acquired limb muscle and severe diaphragm weakness on weaning outcome and mortality: a post hoc analysis of two cohorts
Martin Dres, Boris Jung, Nicolas Molinari, Federico Manna, Bruno-Pierre Dubé, Gerald Chanques, Thomas Similowski, Samir Jaber, Alexandre Demoule
Outcomes of Stenotrophomonas maltophilia hospital-acquired pneumonia in intensive care unit: a nationwide retrospective study
Philippe Guerci, Hugo Bellut, Mokhtar Mokhtari, Julie Gaudefroy, Nicolas Mongardon, Claire Charpentier, Guillaume Louis, Parvine Tashk, Clément Dubost, Stanislas Ledochowski, Antoine Kimmoun, Thomas Godet, Julien Pottecher, Jean-Marc Lalot, Emmanuel Novy, David Hajage, Adrien Bouglé, Jean-Michel Constantin, Thomas Godet, Philippe Guerci, Sebastien Perbet, Stanislas Ledochowski
Value of respiratory variation of aortic peak velocity in predicting children receiving mechanical ventilation: a systematic review and meta-analysis
Xiaoying Wang, Lulu Jiang, Shuai Liu, Yali Ge, Ju Gao
In-line filtration of intravenous infusion may reduce organ dysfunction of adult critical patients
Elke Schmitt, Patrick Meybohm, Eva Herrmann, Karin Ammersbach, Raphaela Endres, Simone Lindau, Philipp Helmer, Kai Zacharowski, Holger Neb
The SOFA score—development, utility and challenges of accurate assessment in clinical trials
Simon Lambden, Pierre Francois Laterre, Mitchell M. Levy, Bruno Francois
Dynamic hyperinflation and intrinsic positive end-expiratory pressure in ARDS patients
Silvia Coppola, Alessio Caccioppola, Sara Froio, Erica Ferrari, Miriam Gotti, Paolo Formenti, Davide Chiumello
Early vs. late coronary angiography in cardiac arrest improves survival and preserves renal function: some confounding factors to consider
Sébastien Redant, Yael Langman, Xavier Beretta-Piccoli, David De Bels, Rachid Attou, Patrick M. Honore
Mortality risk over time after early fluid resuscitation in African children
Elizabeth C. George, Sarah Kiguli, Peter Olupot Olupot, Robert O. Opoka, Charles Engoru, Samuel O. Akech, Richard Nyeko, George Mtove, Ayub Mpoya, Margaret J. Thomason, Jane Crawley, Jennifer A. Evans, Diana M. Gibb, Abdel G. Babiker, Kathryn Maitland, A. Sarah Walker
Predictive value of transabdominal intestinal sonography in critically ill patients: a prospective observational study
Tao Gao, Min-Hua Cheng, Feng-Chan Xi, Yan Chen, Chun Cao, Ting Su, Wei-Qin Li, Wen-Kui Yu
Increased β-Lactams dosing regimens improve clinical outcome in critically ill patients with augmented renal clearance treated for a first episode of hospital or ventilator-acquired pneumonia: a before and after study
Cédric Carrié, Grégoire Chadefaux, Noémie Sauvage, Hugues de Courson, Laurent Petit, Karine Nouette-Gaulain, Bruno Pereira, Matthieu Biais
A comparison of clinical paediatric guidelines for hypotension with population-based lower centiles: a systematic review
Nienke N. Hagedoorn, Joany M. Zachariasse, Henriette A. Moll
Variability in intensive care unit admission among pregnant and postpartum women in Canada: a nationwide population-based observational study
Kazuyoshi Aoyama, Ruxandra Pinto, Joel G. Ray, Andrea D. Hill, Damon C. Scales, Stephen E. Lapinsky, Michelle Hladunewich, Gareth R. Seaward, Robert A. Fowler
Oral mucositis as a pathway for fatal outcome among critically ill patients exposed to chlorhexidine: post hoc analysis of a randomized clinical trial
Wanessa Teixeira Bellissimo-Rodrigues, Mayra Gonçalves Menegueti, Leandro Dorigan de Macedo, Anibal Basile-Filho, Roberto Martinez, Fernando Bellissimo-Rodrigues
Colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia (Magic Bullet study): an investigator-driven, open-label, randomized, noninferiority controlled trial
José M. Cisneros, Clara María Rosso-Fernández, Cristina Roca-Oporto, Gennaro De Pascale, Silvia Jiménez-Jorge, Esteban Fernández-Hinojosa, Dimitrios K. Matthaiou, Paula Ramírez, Ramón Ortiz Díaz-Miguel, Angel Estella, Massimo Antonelli, George Dimopoulos, José Garnacho-Montero, V. Di Gravio, G. Bello, V. González, R. Leal, A. Puppo, J. A. Lepe, A. Gutiérrez-Pizarraya, E. Villarreal, M. C. Espinosa, M. J. Polanco, M. D. López, M. E. Herrera-Gutiérrez, G. Seller, S. Zakinthinos, S. Malachias, A. Komnos, T. Zafeiridis, R. Sierra, A. González, E. Zakynthinos, L. Alvárez-Rocha, M. Victoria de la Torre, P. J. Domínguez, M. Bitsan, A. Koutsoukou, R. Zaragoza, E. De Roberts, J. M. Allegue, J. Carlos Pozo, G. Nakos, R. Ferrer, I. Pneumatikos, P. Vidal, José M. Cisneros, Clara María Rosso-Fernández, Cristina Roca-Oporto, Gennaro De Pascale, Silvia Jiménez-Jorge, Esteban Fernández-Hinojosa, Dimitrios K. Matthaiou, Paula Ramírez, Ramón Ortiz Díaz-Miguel, Angel Estella, Massimo Antonelli, George Dimopoulos, José Garnacho-Montero
Murine sepsis phenotypes and differential treatment effects in a randomized trial of prompt antibiotics and fluids
Christopher W. Seymour, Samantha J. Kerti, Anthony J. Lewis, Jason Kennedy, Emily Brant, John E. Griepentrog, Xianghong Zhang, Derek C. Angus, Chung-Chou H. Chang, Matthew R. Rosengart
Levosimendan in the light of the results of the recent randomized controlled trials: an expert opinion paper
Bernard Cholley, Bruno Levy, Jean-Luc Fellahi, Dan Longrois, Julien Amour, Alexandre Ouattara, Alexandre Mebazaa
The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort
Eleni Karakike, Evdoxia Kyriazopoulou, Iraklis Tsangaris, Christina Routsi, Jean-Louis Vincent, Evangelos J. Giamarellos-Bourboulis
Mechanical ventilation in patients with acute ischaemic stroke: from pathophysiology to clinical practice
Chiara Robba, Giulia Bonatti, Denise Battaglini, Patricia R. M. Rocco, Paolo Pelosi
Ultrasound-based clinical profiles for predicting the risk of intradialytic hypotension in critically ill patients on intermittent dialysis: a prospective observational study
Rogerio da Hora Passos, Juliana Caldas, Joao Gabriel Rosa Ramos, Erica Batista dos Santos Galvão de Melo, Michel Por Deus Ribeiro, Maria Fernanda Coelho Alves, Paulo Benigno Pena Batista, Octavio Henrique Coelho Messeder, Augusto Manoel de Carvalho de Farias, Etienne Macedo, Jean Jacques Rouby
The prognostic value of serum procalcitonin measurements in critically injured patients: a systematic review
Aziza N. AlRawahi, Fatma A. AlHinai, Christopher J. Doig, Chad G. Ball, Elijah Dixon, Zhengwen Xiao, Andrew W. Kirkpatrick
Temporal trends in the use of targeted temperature management after cardiac arrest and association with outcome: insights from the Paris Sudden Death Expertise Centre
Jean-Baptiste Lascarrou, Florence Dumas, Wulfran Bougouin, Richard Chocron, Frankie Beganton, Stephane Legriel, Nadia Aissaoui, Nicolas Deye, Lionel Lamhaut, Daniel Jost, Antoine Vieillard-Baron, Eloi Marijon, Xavier Jouven, Alain Cariou, F. Adnet, J. M. Agostinucci, N. Aissaoui-Balanant, V. Algalarrondo, F. Alla, C. Alonso, W. Amara, D. Annane, C. Antoine, P. Aubry, E. Azoulay, F. Beganton, D. Benhamou, C. Billon, W. Bougouin, J. Boutet, C. Bruel, P. Bruneval, A. Cariou, P. Carli, E. Casalino, C. Cerf, A. Chaib, B. Cholley, Y. Cohen, A. Combes, M. Crahes, D. Da Silva, V. Das, A. Demoule, I. Denjoy, N. Deye, G. Dhonneur, J. L. Diehl, S. Dinanian, L. Domanski, D. Dreyfuss, D. Duboc, J. L. Dubois-Rande, F. Dumas, J. P. Empana, F. Extramiana, M. Fartoukh, F. Fieux, M. Gabbas, E. Gandjbakhch, G. Geri, B. Guidet, F. Halimi, P. Henry, F. Hidden Lucet, P. Jabre, L. Jacob, L. Joseph, D. Jost, X. Jouven, N. Karam, H. Kassim, J. Lacotte, K. Lahlou-Laforet, L. Lamhaut, A. Lanceleur, O. Langeron, T. Lavergne, E. Lecarpentier, A. Leenhardt, N. Lellouche, V. Lemiale, F. Lemoine, F. Linval, T. Loeb, B. Ludes, C. E. Luyt, A. Maltret, N. Mansencal, N. Mansouri, E. Marijon, J. Marty, E. Maury, V. Maxime, B. Megarbane, A. Mekontso-Dessap, H. Mentec, J. P. Mira, X. Monnet, K. Narayanan, N. Ngoyi, M. C. Perier, O. Piot, R. Pirracchio, P. Plaisance, I. Plu, M. Raux, F. Revaux, J. D. Ricard, C. Richard, B. Riou, F. Roussin, F. Santoli, F. Schortgen, A. Sharifzadehgan, G. Sideris, C. Spaulding, J. L. Teboul, J. F. Timsit, J. P. Tourtier, P. Tuppin, C. Ursat, O. Varenne, A. Vieillard-Baron, S. Voicu, K. Wahbi, V. Waldmann
Cumulative fluid accumulation is associated with the development of acute kidney injury and non-recovery of renal function: a retrospective analysis
Jing Zhang, Siobhan Crichton, Alison Dixon, Nina Seylanova, Zhiyong Y. Peng, Marlies Ostermann
Epidemiology and prognosis of anti-infective therapy in the ICU setting during acute pancreatitis: a cohort study
Philippe Montravers, Elie Kantor, Jean-Michel Constantin, Jean-Yves Lefrant, Thomas Lescot, Nicolas Nesseler, Catherine Paugam, Matthieu Jabaudon, Hervé Dupont
Cortisol total/CRP ratio for the prediction of hospital-acquired pneumonia and initiation of corticosteroid therapy in traumatic brain-injured patients
Marwan Bouras, Antoine Roquilly, Pierre-Joachim Mahé, Raphaël Cinotti, Mickaël Vourc’h, Bastien Perrot, Kalyane Bach-Ngohou, Damien Masson, Karim Asehnoune
Expiratory flow limitation in intensive care: prevalence and risk factors
Carlo Alberto Volta, Francesca Dalla Corte, Riccardo Ragazzi, Elisabetta Marangoni, Alberto Fogagnolo, Gaetano Scaramuzzo, Domenico Luca Grieco, Valentina Alvisi, Chiara Rizzuto, Savino Spadaro
A meta-analysis of the effects of therapeutic hypothermia in adult patients with traumatic brain injury
Hanbing Chen, Fei Wu, Penglei Yang, Jun Shao, Qihong Chen, Ruiqiang Zheng
Interleukin-26 is a promising biomarker of sepsis but is it always reliable?
Patrick M. Honore, Aude Mugisha, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani, David De Bels
Risk factors for the development of acute respiratory distress syndrome in mechanically ventilated adults in Peru: a multicenter observational study
Ena Gupta, Shakir Hossen, Matthew R. Grigsby, Phabiola Herrera, Rollin Roldan, Enrique Paz, Amador A. Jaymez, Eduardo E. Chirinos, Jose Portugal, Rocio Quispe, Roy G. Brower, William Checkley, Roy G. Brower, Francesca Capanni, Maria A. Caravedo, Jorge Cerna, William Checkley, Eduardo E. Chirinos, Long Davalos, Aldo De Ferrari, Joshua A. Denney, Augusto Dulanto, Phabiola Herrera, Amador A. Jaymez, Nicole Mongilardi, Carmen Paredes, Enrique Paz, Maria Alejandra Pereda, Jose Portugal, Rocio Quispe, Rollin Roldan, Navid Shams
Initial therapy affects duration of diarrhoea in critically ill patients with Clostridioides difficile infection (CDI)
Carolin F. Manthey, Darja Dranova, Martin Christner, Andreas Drolz, Stefan Kluge, Ansgar W. Lohse, Valentin Fuhrmann
Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study
Brian J. Anderson, Carolyn S. Calfee, Kathleen D. Liu, John P. Reilly, Kirsten N. Kangelaris, Michael G. S. Shashaty, Aili L. Lazaar, Andrew I. Bayliffe, Robert J. Gallop, Todd A. Miano, Thomas G. Dunn, Erik Johansson, Jason Abbott, Alejandra Jauregui, Thomas Deiss, Kathryn Vessel, Annika Belzer, Hanjing Zhuo, Michael A. Matthay, Nuala J. Meyer, Jason D. Christie
Predicting outcome in patients with moderate to severe traumatic brain injury using electroencephalography
Marjolein E. Haveman, Michel J. A. M. Van Putten, Harold W. Hom, Carin J. Eertman-Meyer, Albertus Beishuizen, Marleen C. Tjepkema-Cloostermans
The effect of dexmedetomidine and clonidine on the inflammatory response in critical illness: a systematic review of animal and human studies
Charles A. Flanders, Alistair S. Rocke, Stuart A. Edwardson, J. Kenneth Baillie, Timothy S. Walsh
Dysbiosis of the microbiota in neurocritically ill patients associated with coma and death: ammonia as a potential missing link
Patrick M. Honore, Aude Mugisha, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani, David De Bels
Optimizing ceftolozane-tazobactam dosage during continuous renal replacement therapy: additional insights
Patrick M. Honore, Aude Mugisha, Leonel Barreto Gutierrez, Sebastien Redant, Keitiane Kaefer, Andrea Gallerani, David De Bels
Predicting the clinical trajectory in critically ill patients with sepsis: a cohort study
Peter M. C. Klein Klouwenberg, Cristian Spitoni, Tom van der Poll, Marc J. Bonten, Olaf L. Cremer, Jos F. Frencken, Kirsten van de Groep, Marlies E. Koster-Brouwer, David S. Y. Ong, Diana Verboom, Friso M. de Beer, Lieuwe D. J. Bos, Gerie J. Glas, Roosmarijn T. M. van Hooijdonk, Laura R. A. Schouten, Marleen Straat, Esther Witteveen, Luuk Wieske, Arie J. Hoogendijk, Mischa A. Huson, Lonneke A. van Vught
Improving identification of pulmonary embolism-related out-of-hospital cardiac arrest to optimize thrombolytic therapy during resuscitation
François Javaudin, Jean-Baptiste Lascarrou, Hyacinthe Esquina, Valentine Baert, Hervé Hubert, Brice Leclère, François Javaudin, Jean-Baptiste Lascarrou, Hyacinthe Esquina, Valentine Baert, Hervé Hubert, Brice Leclère
Development of a biomarker mortality risk model in acute respiratory distress syndrome
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The impact of intensive care unit diaries on patients’ and relatives’ outcomes: a systematic review and meta-analysis
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A longitudinal study highlights shared aspects of the transcriptomic response to cardiogenic and septic shock
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Outcomes of hospitalized hematologic oncology patients receiving rapid response system activation for acute deterioration: another time, another way
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Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study
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Dynamic hyperinflation and intrinsic PEEP in ARDS patients: who, when, and how needs more focus?
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Driving pressure is not associated with mortality in mechanically ventilated patients without ARDS
Michael J. Lanspa, Ithan D. Peltan, Jason R. Jacobs, Jeffrey S. Sorensen, Lori Carpenter, Jeffrey P. Ferraro, Samuel M. Brown, Jay G. Berry, Raj Srivastava, Colin K. Grissom
Non-pulsatile blood flow is associated with enhanced cerebrovascular carbon dioxide reactivity and an attenuated relationship between cerebral blood flow and regional brain oxygenation
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Lasting s-ketamine block of spreading depolarizations in subarachnoid hemorrhage: a retrospective cohort study
Edgar Santos, Arturo Olivares-Rivera, Sebastian Major, Renán Sánchez-Porras, Lorenz Uhlmann, Kevin Kunzmann, Roland Zerelles, Modar Kentar, Vasilis Kola, Adrian Hernández Aguilera, Mildred Gutierrez Herrera, Coline L. Lemale, Johannes Woitzik, Jed A. Hartings, Oliver W. Sakowitz, Andreas W. Unterberg, Jens P. Dreier
Prophylactic use of levosimendan in pediatric patients undergoing cardiac surgery: a prospective randomized controlled trial
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Defining benefit threshold for extracorporeal membrane oxygenation in children with sepsis—a binational multicenter cohort study
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