Diabetologia

Up front

Digital health technology and mobile devices for the management of diabetes mellitus: state of the art

Rongzi Shan, Sudipa Sarkar, Seth S. Martin

NAD+ metabolism as a target for metabolic health: have we found the silver bullet?

Niels J. Connell, Riekelt H. Houtkooper, Patrick Schrauwen

Canagliflozin should be prescribed with caution to individuals with type 2 diabetes and high risk of amputation

Matilde Monteiro-Soares, Inês Ribeiro-Vaz, Edward J. Boyko

Gestational diabetes and the risk of cardiovascular disease in women: a systematic review and meta-analysis

Caroline K. Kramer, Sara Campbell, Ravi Retnakaran

A reduction in sedentary behaviour in obese women during pregnancy reduces neonatal adiposity: the DALI randomised controlled trial

Mireille N. M. van Poppel, David Simmons, Roland Devlieger, F. Andre van Assche, Goele Jans, Sander Galjaard, Rosa Corcoy, Juan M. Adelantado, Fidelma Dunne, Jürgen Harreiter, Alexandra Kautzky-Willer, Peter Damm, Elisabeth R. Mathiesen, Dorte M. Jensen, Lise-Lotte Andersen, Mette Tanvig, Annunziata Lapolla, Maria G. Dalfra, Alessandra Bertolotto, Ewa Wender-Ozegowska, Agnieszka Zawiejska, David Hill, Frank J. Snoek, Judith G. M. Jelsma, Gernot Desoye

Effects of canagliflozin on amputation risk in type 2 diabetes: the CANVAS Program

David R. Matthews, Qiang Li, Vlado Perkovic, Kenneth W. Mahaffey, Dick de Zeeuw, Greg Fulcher, Mehul Desai, William R. Hiatt, Mark Nehler, Elisa Fabbrini, Mary Kavalam, Mary Lee, Bruce Neal

Lower limb events in individuals with type 2 diabetes: evidence for an increased risk associated with diuretic use

Louis Potier, Ronan Roussel, Gilberto Velho, Pierre-Jean Saulnier, Anisoara Bumbu, Odette Matar, Fabrice Schneider, Stéphanie Ragot, Michel Marre, Kamel Mohammedi, Samy Hadjadj

Efficacy and safety of evolocumab in individuals with type 2 diabetes mellitus: primary results of the randomised controlled BANTING study

Robert S. Rosenson, Martha L. Daviglus, Yehuda Handelsman, Paolo Pozzilli, Harold Bays, Maria Laura Monsalvo, Mary Elliott-Davey, Ransi Somaratne, Peter Reaven

Pre-diagnostic plasma enterolactone concentrations are associated with lower mortality among individuals with type 2 diabetes: a case-cohort study in the Danish Diet, Cancer and Health cohort

Anne K. Eriksen, Cecilie Kyrø, Natalja P. Nørskov, Kirsten Frederiksen, Knud-Erik Bach Knudsen, Kim Overvad, Rikard Landberg, Anne Tjønneland, Anja Olsen

Eighteen-year alcohol consumption trajectories and their association with risk of type 2 diabetes and its related factors: the China Health and Nutrition Survey

Tianshu Han, Shuang Zhang, Wei Duan, Xinhui Ren, Chunbo Wei, Changhao Sun, Ying Li

Apolipoprotein C-III and its defined lipoprotein subspecies in relation to incident diabetes: the Multi-Ethnic Study of Atherosclerosis

Sarah A. Aroner, Jeremy D. Furtado, Frank M. Sacks, Michael Y. Tsai, Kenneth J. Mukamal, Robyn L. McClelland, Majken K. Jensen

Macrophage alterations in islets of obese mice linked to beta cell disruption in diabetes

Jeng Yie Chan, Kailun Lee, Emma L. Maxwell, Cassandra Liang, D. Ross Laybutt

Pregnancy in human IAPP transgenic mice recapitulates beta cell stress in type 2 diabetes

Tatyana Gurlo, Sarah Kim, Alexandra E. Butler, Chang Liu, Lina Pei, Madeline Rosenberger, Peter C. Butler

No direct effect of SGLT2 activity on glucagon secretion

Rune E. Kuhre, Seyed M. Ghiasi, Alice E. Adriaenssens, Nicolai J. Wewer Albrechtsen, Daniel B. Andersen, Alexander Aivazidis, Lihua Chen, Thomas Mandrup-Poulsen, Cathrine Ørskov, Fiona M. Gribble, Frank Reimann, Nils Wierup, Björn Tyrberg, Jens J. Holst

Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

Thomas Bryrup, Cæcilie W. Thomsen, Timo Kern, Kristine H. Allin, Ivan Brandslund, Niklas R. Jørgensen, Henrik Vestergaard, Torben Hansen, Tue H. Hansen, Oluf Pedersen, Trine Nielsen

Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue

Boone M. Prentice, Nathaniel J. Hart, Neil Phillips, Rachana Haliyur, Audra Judd, Radhika Armandala, Jeffrey M. Spraggins, Cindy L. Lowe, Kelli L. Boyd, Roland W. Stein, Christopher V. Wright, Jeremy L. Norris, Alvin C. Powers, Marcela Brissova, Richard M. Caprioli

Effects of long-term exercise on plasma adipokine levels and inflammation-related gene expression in subcutaneous adipose tissue in sedentary dysglycaemic, overweight men and sedentary normoglycaemic men of healthy weight

Sindre Lee, Frode Norheim, Torgrim M. Langleite, Hanne L. Gulseth, Kåre I. Birkeland, Christian A. Drevon

Elevated brain glutamate levels in type 1 diabetes: correlations with glycaemic control and age of disease onset but not with hypoglycaemia awareness status

Evita C. Wiegers, Hanne M. Rooijackers, Jack J.A. van Asten, Cees J. Tack, Arend Heerschap, Bastiaan E. de Galan, Marinette van der Graaf

Pancreatic kallikrein protects against diabetic retinopathy in KK Cg-Ay/J and high-fat diet/streptozotocin-induced mouse models of type 2 diabetes

Ying Cheng, Xiaochen Yu, Jie Zhang, Yunpeng Chang, Mei Xue, Xiaoyu Li, Yunhong Lu, Ting Li, Ziyu Meng, Long Su, Bei Sun, Liming Chen

Impaired whole-body heat loss in type 1 diabetes during exercise in the heat: a cause for concern?

Sean R. Notley, Martin P. Poirier, Jane E. Yardley, Ronald J. Sigal, Glen P. Kenny

Molecular regulation of the renin–angiotensin system by sodium–glucose cotransporter 2 inhibition in type 1 diabetes mellitus

Chantal Kopecky, Yuliya Lytvyn, Oliver Domenig, Marlies Antlanger, Johannes J. Kovarik, Christopher C. Kaltenecker, Marko Poglitsch, Bruce A. Perkins, Kerry-Anne Rye, David Z. I. Cherney, Marcus D. Säemann

Underpowered or negative? A crucial distinction

Ole L. Dollerup, Jonas T. Treebak, Niels Jessen

Underpowered or negative? A crucial distinction. Reply to Dollerup OL, Treebak JT, Jessen N [letter]

Niels J. Connell, Riekelt H. Houtkooper, Patrick Schrauwen

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence

Oskar Skog, Karin Klingel, Merja Roivainen, Olle Korsgren

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence. Reply to Skog O, Klingel K, Roivainen M et al [letter]

Jessica L. Dunne, Sarah J. Richardson, Mark A. Atkinson, Maria E. Craig, Knut Dahl-Jørgensen, Malin Flodström-Tullberg, Heikki Hyöty, Richard E. Lloyd, Noel G. Morgan, Alberto Pugliese