Ausgabe 7/2016
Inhalt (36 Artikel)
Up front
SGLT2 Inhibition and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms?
Naveed Sattar, James McLaren, Søren L. Kristensen, David Preiss, John J. McMurray
In vivo imaging of beta cells with radiotracers: state of the art, prospects and recommendations for development and use
Olof Eriksson, Maren Laughlin, Maarten Brom, Pirjo Nuutila, Michael Roden, Albert Hwa, Riccardo Bonadonna, Martin Gotthardt
Islet-intrinsic effects of CFTR mutation
Fiona N. Manderson Koivula, Neville H. McClenaghan, Alan G. S. Harper, Catriona Kelly
Serotonin competence of mouse beta cells during pregnancy
Lotte Goyvaerts, Anica Schraenen, Frans Schuit
Glucagon is the key factor in the development of diabetes
Young H. Lee, May-Yun Wang, Xin-Xin Yu, Roger H. Unger
Risk factors for gestational diabetes: is prevention possible?
Cuilin Zhang, Shristi Rawal, Yap Seng Chong
Gestational diabetes mellitus and long-term consequences for mother and offspring: a view from Denmark
Peter Damm, Azadeh Houshmand-Oeregaard, Louise Kelstrup, Jeannet Lauenborg, Elisabeth R. Mathiesen, Tine D. Clausen
Quantification of the type 2 diabetes risk in women with gestational diabetes: a systematic review and meta-analysis of 95,750 women
Girish Rayanagoudar, Amal A. Hashi, Javier Zamora, Khalid S. Khan, Graham A. Hitman, Shakila Thangaratinam
Acute renal effects of the GLP-1 receptor agonist exenatide in overweight type 2 diabetes patients: a randomised, double-blind, placebo-controlled trial
Lennart Tonneijck, Mark M. Smits, Marcel H. A. Muskiet, Trynke Hoekstra, Mark H. H. Kramer, A. H. Jan Danser, Michaela Diamant, Jaap A. Joles, Daniël H. van Raalte
Higher body fat percentage is associated with enhanced temperature perception in NAFLD: results from the randomised Wessex Evaluation of fatty Liver and Cardiovascular markers in NAFLD with OMacor thErapy trial (WELCOME) trial
Geraldine F. Clough, Keith G. McCormick, Eleonora Scorletti, Lokpal Bhatia, Philip C. Calder, Michael J. Griffin, Christopher D. Byrne
Neonatal diabetes caused by a homozygous KCNJ11 mutation demonstrates that tiny changes in ATP sensitivity markedly affect diabetes risk
Natascia Vedovato, Edward Cliff, Peter Proks, Varadarajan Poovazhagi, Sarah E. Flanagan, Sian Ellard, Andrew T. Hattersley, Frances M. Ashcroft
Burden of diabetes in Australia: life expectancy and disability-free life expectancy in adults with diabetes
Lili Huo, Jonathan E. Shaw, Evelyn Wong, Jessica L. Harding, Anna Peeters, Dianna J. Magliano
Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank
Wei Gan, Robin G. Walters, Michael V. Holmes, Fiona Bragg, Iona Y. Millwood, Karina Banasik, Yiping Chen, Huaidong Du, Andri Iona, Anubha Mahajan, Ling Yang, Zheng Bian, Yu Guo, Robert J. Clarke, Liming Li, Mark I. McCarthy, Zhengming Chen
Impaired pancreatic beta cell compensatory function is the main cause of type 2 diabetes in individuals with high genetic risk: a 9 year prospective cohort study in the Chinese population
Jing Yan, Danfeng Peng, Feng Jiang, Rong Zhang, Miao Chen, Tao Wang, Dandan Yan, Shiyun Wang, Xuhong Hou, Yuqian Bao, Cheng Hu, Weiping Jia
Differential regulation of serum microRNA expression by HNF1β and HNF1α transcription factors
Wojciech Fendler, Joanna Madzio, Kamil Kozinski, Kashyap Patel, Justyna Janikiewicz, Magdalena Szopa, Adam Tracz, Maciej Borowiec, Przemyslawa Jarosz-Chobot, Malgorzata Mysliwiec, Agnieszka Szadkowska, Andrew T. Hattersley, Sian Ellard, Maciej T. Malecki, Agnieszka Dobrzyn, Wojciech Mlynarski
The zinc finger transcription factor PW1/PEG3 restrains murine beta cell cycling
Mozhdeh Sojoodi, Leslie Stradiot, Karo Tanaka, Yves Heremans, Gunter Leuckx, Vanessa Besson, Willem Staels, Mark Van de Casteele, Giovanna Marazzi, David Sassoon, Harry Heimberg, Paola Bonfanti
Autophagy is a major regulator of beta cell insulin homeostasis
Yael Riahi, Jakob D. Wikstrom, Etty Bachar-Wikstrom, Nava Polin, Hava Zucker, Myung-Shik Lee, Wenying Quan, Leena Haataja, Ming Liu, Peter Arvan, Erol Cerasi, Gil Leibowitz
Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells
Mohammed Bensellam, Emma L. Maxwell, Jeng Yie Chan, Jude Luzuriaga, Phillip K. West, Jean-Christophe Jonas, Jenny E. Gunton, D. Ross Laybutt
Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice
Samira Alliouachene, Benoit Bilanges, Claire Chaussade, Wayne Pearce, Lazaros C. Foukas, Cheryl L. Scudamore, Larissa S. Moniz, Bart Vanhaesebroeck
Neuronal human BACE1 knockin induces systemic diabetes in mice
Kaja Plucińska, Ruta Dekeryte, David Koss, Kirsty Shearer, Nimesh Mody, Phillip D. Whitfield, Mary K. Doherty, Marco Mingarelli, Andy Welch, Gernot Riedel, Mirela Delibegovic, Bettina Platt
A decrease in hepatic microRNA-9 expression impairs gluconeogenesis by targeting FOXO1 in obese mice
Caifeng Yan, Jinfeng Chen, Min Li, Wenying Xuan, Dongming Su, Hui You, Yujie Huang, Nuoqi Chen, Xiubin Liang
Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin
Atsushi Iida, Yusuke Seino, Ayako Fukami, Ryuya Maekawa, Daisuke Yabe, Shinobu Shimizu, Keita Kinoshita, Yusuke Takagi, Takako Izumoto, Hidetada Ogata, Kota Ishikawa, Nobuaki Ozaki, Shin Tsunekawa, Yoji Hamada, Yutaka Oiso, Hiroshi Arima, Yoshitaka Hayashi
Prospective study on microangiopathy in type 2 diabetic foot ulcer
Fabio Fiordaliso, Giacomo Clerici, Serena Maggioni, Maurizio Caminiti, Cinzia Bisighini, Deborah Novelli, Daniela Minnella, Alessandro Corbelli, Riccardo Morisi, Alberto De Iaco, Ezio Faglia
Urinary biomarkers are associated with incident cardiovascular disease, all-cause mortality and deterioration of kidney function in type 2 diabetic patients with microalbuminuria
Bernt Johan von Scholten, Henrik Reinhard, Tine W. Hansen, Jens Oellgaard, Hans-Henrik Parving, Peter K. Jacobsen, Peter Rossing
C66 ameliorates diabetic nephropathy in mice by both upregulating NRF2 function via increase in miR-200a and inhibiting miR-21
Hao Wu, Lili Kong, Yi Tan, Paul N. Epstein, Jun Zeng, Junlian Gu, Guang Liang, Maiying Kong, Xiangmei Chen, Lining Miao, Lu Cai
The intriguing relationship between epilepsy and type 1 diabetes mellitus
Josemir W. Sander, Jan Novy, Mark R. Keezer
The intriguing relationship between epilepsy and type 1 diabetes mellitus. Reply to Sander JW, Novy J, Keezer MR [letter]
I-Ching Chou, Chia-Hung Kao
Erratum to: SGLT2 Inhibition and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms?
Naveed Sattar, James McLaren, Søren L. Kristensen, David Preiss, John J. McMurray
Erratum to: Autophagy is a major regulator of beta cell insulin homeostasis
Yael Riahi, Jakob D. Wikstrom, Etty Bachar-Wikstrom, Nava Polin, Hava Zucker, Myung-Shik Lee, Wenying Quan, Leena Haataja, Ming Liu, Peter Arvan, Erol Cerasi, Gil Leibowitz