Ausgabe 1/2015
Inhalt (77 Artikel)
Transcriptional response in normal mouse tissues after i.v. 211At administration - response related to absorbed dose, dose rate, and time
Britta Langen, Nils Rudqvist, Toshima Z Parris, Emil Schüler, Johan Spetz, Khalil Helou, Eva Forssell-Aronsson
Molecular imaging of angiogenesis after myocardial infarction by 111In-DTPA-cNGR and 99mTc-sestamibi dual-isotope myocardial SPECT
Geert Hendrikx, Marijke De Saint-Hubert, Ingrid Dijkgraaf, Matthias Bauwens, Kim Douma, Roel Wierts, Ivo Pooters, Nynke MS Van den Akker, Tilman M Hackeng, Mark J Post, Felix M Mottaghy
Role of CD8-positive cells in radioimmunotherapy utilizing 177Lu-mAbs in an immunocompetent rat colon carcinoma model
Erika Elgström, Sophie E Eriksson, Tomas G Ohlsson, Rune Nilsson, Jan Tennvall
Identifying erlotinib-sensitive non-small cell lung carcinoma tumors in mice using [11C]erlotinib PET
Galith Abourbeh, Batel Itamar, Olga Salnikov, Sergey Beltsov, Eyal Mishani
The ultimate radiochemical nightmare: upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule
Janneke IM van Uhm, Gerard WM Visser, Marcel J van der Schans, Albert A Geldof, Eric JH Meuleman, Jakko A Nieuwenhuijzen
An assessment of the characteristics and quality of diagnostic accuracy studies for positron emission tomography conducted in Japan: a systematic review
Shuhei Nomura, Akinori Hisashige, Daisuke Yoneoka, Mikiko Kanda, Karin Miyamoto, Miwako Segawa, Erika Ota, Kenji Shibuya
Comparison of 4′-[methyl-11C]thiothymidine (11C-4DST) and 3′-deoxy-3′-[18F]fluorothymidine (18F-FLT) PET/CT in human brain glioma imaging
Yasunori Toyota, Keisuke Miyake, Nobuyuki Kawai, Tetsuhiro Hatakeyama, Yuka Yamamoto, Jun Toyohara, Yoshihiro Nishiyama, Takashi Tamiya
64Cu-DOTA-trastuzumab PET imaging and HER2 specificity of brain metastases in HER2-positive breast cancer patients
Hiroaki Kurihara, Akinobu Hamada, Masayuki Yoshida, Schuichi Shimma, Jun Hashimoto, Kan Yonemori, Hitomi Tani, Yasuji Miyakita, Yousuke Kanayama, Yasuhiro Wada, Makoto Kodaira, Mayu Yunokawa, Harukaze Yamamoto, Chikako Shimizu, Kazuhiro Takahashi, Yasuyoshi Watanabe, Yasuhiro Fujiwara, Kenji Tamura
SPECT imaging of glioma with radioiodinated CLINDE: evidence from a mouse GL26 glioma model
Stergios Tsartsalis, Noé Dumas, Benjamin B Tournier, Tien Pham, Marcelle Moulin-Sallanon, Marie-Claude Grégoire, Yves Charnay, Philippe Millet
Heterogeneity of intratumoral 111In-ibritumomab tiuxetan and 18F-FDG distribution in association with therapeutic response in radioimmunotherapy for B-cell non-Hodgkin’s lymphoma
Kohei Hanaoka, Makoto Hosono, Yoichi Tatsumi, Kazunari Ishii, Sung-Woon Im, Norio Tsuchiya, Kenta Sakaguchi, Itaru Matsumura
The effect of radiation exposure on multidrug resistance: in vitro and in vivo studies using non-small lung cancer cells
Shohei Kanno, Keita Utsunomiya, Yumiko Kono, Noboru Tanigawa, Satoshi Sawada
The diagnostic accuracy of dopamine transporter SPECT imaging to detect nigrostriatal cell loss in patients with Parkinson’s disease or clinically uncertain parkinsonism: a systematic review
Sven R Suwijn, Caroline JM van Boheemen, Rob J de Haan, Gerrit Tissingh, Jan Booij, Rob MA de Bie
[18F]FDG-6-P as a novel in vivo tool for imaging staphylococcal infections
Bethany Mills, Ramla O Awais, Jeni Luckett, Dave Turton, Paul Williams, Alan C Perkins, Philip J Hill
A comparative PET imaging study with the reversible and irreversible EGFR tyrosine kinase inhibitors [11C]erlotinib and [18F]afatinib in lung cancer-bearing mice
Paul Slobbe, Albert D Windhorst, Marijke Stigter-van Walsum, Egbert F Smit, Heiko G Niessen, Flavio Solca, Gerd Stehle, Guus A M S van Dongen, Alex J Poot
Evaluation of elastix-based propagated align algorithm for VOI- and voxel-based analysis of longitudinal 18F-FDG PET/CT data from patients with non-small cell lung cancer (NSCLC)
Gerald SMA Kerner, Alexander Fischer, Michel JB Koole, Jan Pruim, Harry JM Groen
Optimisation of quantitative lung SPECT applied to mild COPD: a software phantom simulation study
Pernilla Norberg, Anna Olsson, Gudrun Alm Carlsson, Michael Sandborg, Agnetha Gustafsson
Neurotensin receptors in pancreatic ductal carcinomas
Meike Körner, Beatrice Waser, Oliver Strobel, Markus Büchler, Jean Claude Reubi
Fluorescence-guided development of a tricistronic vector encoding bimodal optical and nuclear genetic reporters for in vivo cellular imaging
Adam Badar, Louise Kiru, Tammy L Kalber, Amit Jathoul, Karin Straathof, Erik Årstad, Mark F Lythgoe, Martin Pule
Novel 89Zr cell labeling approach for PET-based cell trafficking studies
Aditya Bansal, Mukesh K Pandey, Yunus E Demirhan, Jonathan J Nesbitt, Ruben J Crespo-Diaz, Andre Terzic, Atta Behfar, Timothy R DeGrado
FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice
Behrooz H Yousefi, Boris von Reutern, Daniela Scherübl, André Manook, Markus Schwaiger, Timo Grimmer, Gjermund Henriksen, Stefan Förster, Alexander Drzezga, Hans-Jürgen Wester
Effect of postconditioning on dynamic expression of tenascin-C and left ventricular remodeling after myocardial ischemia and reperfusion
Junichi Taki, Anri Inaki, Hiroshi Wakabayashi, Ichiro Matsunari, Kyoko Imanaka-Yoshida, Kazuma Ogawa, Michiaki Hiroe, Kazuhiro Shiba, Toshimichi Yoshida, Seigo Kinuya
Twins in spirit - episode I: comparative preclinical evaluation of [68Ga]DOTATATE and [68Ga]HA-DOTATATE
Margret Schottelius, Jakub Šimeček, Frauke Hoffmann, Marina Willibald, Markus Schwaiger, Hans-Jürgen Wester
Evaluation of the specificity of [18F]fludarabine PET/CT in a xenograft model of follicular lymphoma: comparison with [18F]FDG and impact of rituximab therapy
Narinée Hovhannisyan, Stéphane Guillouet, Fabien Fillesoye, Martine Dhilly, Delphine Patin, Françoise Galateau, Michel Leporrier, Louisa Barré
Whole-body organ-level and kidney micro-dosimetric evaluations of 64Cu-loaded HER2/ErbB2-targeted liposomal doxorubicin (64Cu-MM-302) in rodents and primates
Daniel F Gaddy, Helen Lee, Jinzi Zheng, David A Jaffray, Thomas J Wickham, Bart S Hendriks
Somatostatin receptor subtype 2 in high-grade gliomas: PET/CT with 68Ga-DOTA-peptides, correlation to prognostic markers, and implications for targeted radiotherapy
Aida Kiviniemi, Maria Gardberg, Janek Frantzén, Marko Pesola, Ville Vuorinen, Riitta Parkkola, Tuula Tolvanen, Sami Suilamo, Jarkko Johansson, Pauliina Luoto, Jukka Kemppainen, Anne Roivainen, Heikki Minn
Metabolically active tumour volume segmentation from dynamic [18F]FLT PET studies in non-small cell lung cancer
Lieke L Hoyng, Virginie Frings, Otto S Hoekstra, Laura M Kenny, Eric O Aboagye, Ronald Boellaard
GMP-compliant 68Ga radiolabelling in a conventional small-scale radiopharmacy: a feasible approach for routine clinical use
Roeland Vis, Jules Lavalaye, Ewoudt MW van de Garde
Indium 111-labeled J591 anti-PSMA antibody for vascular targeted imaging in progressive solid tumors
Neeta Pandit-Taskar, Joseph A O’Donoghue, Chaitanya R Divgi, Eze A Wills, Lawrence Schwartz, Mithat Gönen, Peter Smith-Jones, Neil H Bander, Howard I Scher, Steven M Larson, Michael J Morris
Differentiation of malignant tumours from granulomas by using dynamic [18F]-fluoro-L-α-methyltyrosine positron emission tomography
Aiko Yamaguchi, Hirofumi Hanaoka, Yutaka Fujisawa, Songji Zhao, Kazutomo Suzue, Akihiro Morita, Hideyuki Tominaga, Tetsuya Higuchi, Hajime Hisaeda, Yoshito Tsushima, Yuji Kuge, Yasuhiko Iida
Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer
Azeem Saleem, Graham E Searle, Laura M Kenny, Mickael Huiban, Kasia Kozlowski, Adam D Waldman, Laura Woodley, Carlo Palmieri, Charles Lowdell, Tomomi Kaneko, Philip S Murphy, Mike R Lau, Eric O Aboagye, Raoul C Coombes
The association of tumor-to-background ratios and SUVmax deviations related to point spread function and time-of-flight F18-FDG-PET/CT reconstruction in colorectal liver metastases
Julian MM Rogasch, Ingo G Steffen, Frank Hofheinz, Oliver S Großer, Christian Furth, Konrad Mohnike, Peter Hass, Mathias Walke, Ivayla Apostolova, Holger Amthauer
Metabolic liver function measured in vivo by dynamic 18F-FDGal PET/CT without arterial blood sampling
Jacob Horsager, Ole Lajord Munk, Michael Sørensen
Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer’s disease
Guruswami SM Sundaram, Dhruva Dhavale, Julie L Prior, Jothilingam Sivapackiam, Richard Laforest, Paul Kotzbauer, Vijay Sharma
Radiosynthesis and first preclinical evaluation of the novel norepinephrine transporter pet-ligand [11C]ME@HAPTHI
Christina Rami-Mark, Neydher Berroterán-Infante, Cecile Philippe, Stefanie Foltin, Chrysoula Vraka, Alexander Hoepping, Rupert Lanzenberger, Marcus Hacker, Markus Mitterhauser, Wolfgang Wadsak
A new compartmental method for the analysis of liver FDG kinetics in small animal models
Sara Garbarino, Valentina Vivaldi, Fabrice Delbary, Giacomo Caviglia, Michele Piana, Cecilia Marini, Selene Capitanio, Iolanda Calamia, Ambra Buschiazzo, Gianmario Sambuceti
Early side effects and first results of radioligand therapy with 177Lu-DKFZ-617 PSMA of castrate-resistant metastatic prostate cancer: a two-centre study
Hojjat Ahmadzadehfar, Kambiz Rahbar, Stefan Kürpig, Martin Bögemann, Michael Claesener, Elisabeth Eppard, Florian Gärtner, Sebastian Rogenhofer, Michael Schäfers, Markus Essler
Imaging of reactive oxygen species in focal ischemic mouse brain using a radical trapping tracer [3H]hydromethidine
Kohji Abe, Misato Tonomura, Miwa Ito, Nozomi Takai, Natsumi Imamoto, Takemi Rokugawa, Sotaro Momosaki, Kazumi Fukumoto, Kenji Morimoto, Osamu Inoue
Imaging of reactive oxygen species using [3H]hydromethidine in mice with cisplatin-induced nephrotoxicity
Nozomi Takai, Kohji Abe, Misato Tonomura, Natsumi Imamoto, Kazumi Fukumoto, Miwa Ito, Sotaro Momosaki, Kae Fujisawa, Kenji Morimoto, Nobuo Takasu, Osamu Inoue
Clinical value of measurement of pulmonary radioaerosol mucociliary clearance in the work up of primary ciliary dyskinesia
Mathias Munkholm, Kim Gjerum Nielsen, Jann Mortensen
Absorption, distribution and excretion of intravenously injected 68Ge/68Ga generator eluate in healthy rats, and estimation of human radiation dosimetry
Anu Autio, Helena Virtanen, Tuula Tolvanen, Heidi Liljenbäck, Vesa Oikonen, Tiina Saanijoki, Riikka Siitonen, Meeri Käkelä, Andrea Schüssele, Mika Teräs, Anne Roivainen
Synthesis and evaluation in rats of homologous series of [18F]-labeled dopamine D2/3 receptor agonists based on the 2-aminomethylchroman scaffold as potential PET tracers
Vladimir Shalgunov, Jan-Peter van Wieringen, Henk M. Janssen, P. Michel Fransen, Rudi A.J.O. Dierckx, Martin C. Michel, Jan Booij, Philip H. Elsinga
Perfusion vector—a new method to quantify myocardial perfusion scintigraphy images: a simulation study with validation in patients
David Minarik, Martin Senneby, Per Wollmer, Alva Mansten, Karl Sjöstrand, Lars Edenbrandt, Elin Trägårdh
Development of a clickable bimodal fluorescent/PET probe for in vivo imaging
Andreas Paulus, Pooja Desai, Brandon Carney, Giuseppe Carlucci, Thomas Reiner, Christian Brand, Wolfgang A Weber
Non-invasive imaging of implanted peritoneal carcinomatosis in mice using PET and bioluminescence imaging
J. Stollfuss, N. Landvogt, M. Abenstein, S. Ziegler, M. Schwaiger, R. Senekowitsch-Schmidtke, H. Wieder
A novel 11C-labeled thymidine analog, [11C]AZT, for tumor imaging by positron emission tomography
Tsuyoshi Tahara, Zhouen Zhang, Masahiro Ohno, Yukako Hirao, Nami Hosaka, Hisashi Doi, Masaaki Suzuki, Hirotaka Onoe
Radioiodinated PARP1 tracers for glioblastoma imaging
Beatriz Salinas, Christopher P. Irwin, Susanne Kossatz, Alexander Bolaender, Gabriela Chiosis, Nagavarakishore Pillarsetty, Wolfgang A. Weber, Thomas Reiner
Evaluation of immune cell markers in tumor tissue treated with radioimmunotherapy in an immunocompetent rat colon carcinoma model
Erika Elgström, Sophie E. Eriksson, Otto Ljungberg, Pär-Ola Bendahl, Tomas G. Ohlsson, Rune Nilsson, Jan Tennvall
Reduced acquisition times in whole body bone scintigraphy using a noise-reducing Pixon®-algorithm—a qualitative evaluation study
Oscar Ardenfors, Ulrika Svanholm, Hans Jacobsson, Patricia Sandqvist, Per Grybäck, Cathrine Jonsson
Further validation to support clinical translation of [18F]FTC-146 for imaging sigma-1 receptors
Bin Shen, Michelle L. James, Lauren Andrews, Christopher Lau, Stephanie Chen, Mikael Palner, Zheng Miao, Natasha C. Arksey, Adam J. Shuhendler, Shawn Scatliffe, Kota Kaneshige, Stanley M. Parsons, Christopher R. McCurdy, Ahmad Salehi, Sanjiv S. Gambhir, Frederick T. Chin
A phase II clinical trial to investigate the effect of pioglitazone on 18F-FDG uptake in malignant lesions
Yeon-Hee Han, Seong Young Kwon, Jeonghun Kim, Chang Ju Na, Sehun Choi, Jung-Joon Min, Hee-Seung Bom, Young-Chul Kim, In-Jae Oh, Han-Jung Chae, Seok Tae Lim, Myung-Hee Sohn, Hwan-Jeong Jeong
Inhomogeneous myocardial stress perfusion in SPECT studies predicts future allograft dysfunction in heart transplant recipients
Christian Wenning, Alexis Vrachimis, Angelo Dell´Aquila, Alvyda Penning, Jörg Stypmann, Michael Schäfers
Rapid kit-based 68Ga-labelling and PET imaging with THP-Tyr3-octreotate: a preliminary comparison with DOTA-Tyr3-octreotate
Michelle T. Ma, Carleen Cullinane, Kelly Waldeck, Peter Roselt, Rodney J. Hicks, Philip J. Blower
Somatostatin receptor PET/CT in restaging of typical and atypical lung carcinoids
Vikas Prasad, Ingo G. Steffen, Marianne Pavel, Timm Denecke, Elisabeth Tischer, Konstantina Apostolopoulou, Andreas Pascher, Ruza Arsenic, Winfried Brenner
Evaluation of the delivered activity of yttrium-90 resin microspheres using sterile water and 5 % glucose during administration
Hojjat Ahmadzadehfar, Carsten Meyer, Claus Christian Pieper, Ralph Bundschuh, Marianne Muckle, Florian Gärtner, Hans Heinz Schild, Markus Essler
(18F)FDG-PET brain imaging during the micturition cycle in rats detects regions involved in bladder afferent signalling
Yves Deruyver, Roma Rietjens, Jan Franken, Silvia Pinto, Ann Van Santvoort, Cindy Casteels, Thomas Voets, Dirk De Ridder
Imaging cerebral tryptophan metabolism in brain tumor-associated depression
Edit Bosnyák, David O. Kamson, Michael E. Behen, Geoffrey R. Barger, Sandeep Mittal, Csaba Juhász
Longitudinal tumor hypoxia imaging with [18F]FAZA-PET provides early prediction of nanoliposomal irinotecan (nal-IRI) treatment activity
Jinzi Zheng, Stephan G. Klinz, Raquel De Souza, Jonathan Fitzgerald, David A. Jaffray
Optimal definition of biological tumor volume using positron emission tomography in an animal model
Ingrid Wu, Hao Wang, David Huso, Richard L. Wahl
Gene expression signature in mouse thyroid tissue after 131I and 211At exposure
Nils Rudqvist, Johan Spetz, Emil Schüler, Britta Langen, Toshima Z. Parris, Khalil Helou, Eva Forssell-Aronsson
Hybrid PET/optical imaging of integrin αVβ3 receptor expression using a 64Cu-labeled streptavidin/biotin-based dimeric RGD peptide
Choong Mo Kang, Hyun-Jung Koo, Gwang Il An, Yearn Seong Choe, Joon Young Choi, Kyung-Han Lee, Byung-Tae Kim
Quantifying and correcting for tail vein extravasation in small animal PET scans in cancer research: is there an impact on therapy assessment?
Charline Lasnon, Audrey Emmanuelle Dugué, Mélanie Briand, Soizic Dutoit, Nicolas Aide
Optimization of combined temozolomide and peptide receptor radionuclide therapy (PRRT) in mice after multimodality molecular imaging studies
Sander M. Bison, Joost C. Haeck, K. Bol, S. J. Koelewijn, H. C. Groen, M. Melis, J. F. Veenland, M. R. Bernsen, M. de Jong
99mTc-MDP bone scintigraphy of the hand: comparing the use of novel cadmium zinc telluride (CZT) and routine NaI(Tl) detectors
Victoria Koulikov, Hedva Lerman, Mikhail Kesler, Einat Even-Sapir
A method for accurate spatial registration of PET images and histopathology slices
Tanuj Puri, Anastasia Chalkidou, Rhonda Henley-Smith, Arunabha Roy, Paul R. Barber, Teresa Guerrero-Urbano, Richard Oakley, Ricard Simo, Jean-Pierre Jeannon, Mark McGurk, Edward W. Odell, Michael J. O’Doherty, Paul K. Marsden
Modeling [18F]-FDG lymphoid tissue kinetics to characterize nonhuman primate immune response to Middle East respiratory syndrome-coronavirus aerosol challenge
Svetlana Chefer, David Thomasson, Jurgen Seidel, Richard C. Reba, J. Kyle Bohannon, Mathew G. Lackemeyer, Chris Bartos, Philip J. Sayre, Laura Bollinger, Lisa E. Hensley, Peter B. Jahrling, Reed F. Johnson
Alterations in androgen deprivation enhanced prostate-specific membrane antigen (PSMA) expression in prostate cancer cells as a target for diagnostics and therapy
B. Meller, F. Bremmer, C. O. Sahlmann, S. Hijazi, C. Bouter, L. Trojan, J. Meller, P. Thelen
Statistical and radiobiological analysis of the so-called thyroid stunning
Stephan Walrand, Michel Hesse, François Jamar
[111In]PSMA-I&T: expanding the spectrum of PSMA-I&T applications towards SPECT and radioguided surgery
Margret Schottelius, Martina Wirtz, Matthias Eiber, Tobias Maurer, Hans-Jürgen Wester
Non-invasive molecular imaging of inflammatory macrophages in allograft rejection
Alexander S. G. O’Neill, Samantha Y. A. Terry, Kathryn Brown, Lucy Meader, Andrew M. S. Wong, Jonathan D. Cooper, Paul R. Crocker, Wilson Wong, Gregory E. D. Mullen
Radiation dosimetry and biodistribution in non-human primates of the sodium/iodide PET ligand [18F]-tetrafluoroborate
J. M. Marti-Climent, M. Collantes, M. Jauregui-Osoro, G. Quincoces, E. Prieto, I. Bilbao, M. Ecay, J. A. Richter, I. Peñuelas
Targeting activated hepatic stellate cells (aHSCs) for liver fibrosis imaging
Dan Li, Li He, Huizhuang Guo, Hanwei Chen, Hong Shan
Correlation between apoptosis and left ventricular remodeling in subacute phase of myocardial ischemia and reperfusion
Hiroshi Wakabayashi, Junichi Taki, Anri Inaki, Kazuhiro Shiba, Ichiro Matsunari, Seigo Kinuya
Radiation dosimetry of [18F]VAT in nonhuman primates
Morvarid Karimi, Zhude Tu, Xuyi Yue, Xiang Zhang, Hongjun Jin, Joel S. Perlmutter, Richard Laforest
Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue
Joachim Pfister, Dominik Summer, Christine Rangger, Milos Petrik, Elisabeth von Guggenberg, Paolo Minazzi, Giovanni B. Giovenzana, Luigi Aloj, Clemens Decristoforo
Circadian rhythm influences genome-wide transcriptional responses to 131I in a tissue-specific manner in mice
Britta Langen, Nils Rudqvist, Toshima Z. Parris, Khalil Helou, Eva Forssell-Aronsson
18F-FDG PET scanning of abdominal aortic aneurysms and correlation with molecular characteristics: a systematic review
U. T. Timur, J. A. van Herwaarden, D. Mihajlovic, P. De Jong, W. Mali, F. L. Moll
The dog prostate cancer (DPC-1) model: a reliable tool for molecular imaging of prostate tumors and metastases
Simone Chevalier, Serge Moffett, Eric Turcotte, Murillo Luz, Lyne Chauvette, Vilma Derbekyan, Eleonora Scarlata, Fatima Zouanat, Armen G. Aprikian, Maurice Anidjar