Ausgabe 1/2022
Inhalt (103 Artikel)
Hypoxia increases expression of selected blood–brain barrier transporters GLUT-1, P-gp, SLC7A5 and TFRC, while maintaining barrier integrity, in brain capillary endothelial monolayers
Burak Ozgür, Hans Christian Cederberg Helms, Erica Tornabene, Birger Brodin
Intercompartmental communication between the cerebrospinal and adjacent spaces during intrathecal infusions in an acute ovine in-vivo model
Anthony Podgoršak, Nina Eva Trimmel, Markus Florian Oertel, Sara Qvarlander, Margarete Arras, Anders Eklund, Miriam Weisskopf, Marianne Schmid Daners
Facilitating drug delivery in the central nervous system by opening the blood-cerebrospinal fluid barrier with a single low energy shockwave pulse
Yi Kung, Kuan-Yu Chen, Wei-Hao Liao, Yi-Hua Hsu, Chueh-Hung Wu, Ming-Yen Hsiao, Abel P.-H. Huang, Wen-Shiang Chen
The timed up and go test in idiopathic normal pressure hydrocephalus: a Nationwide Study of 1300 patients
Nina Sundström, Johanna Rydja, Johan Virhammar, Lena Kollén, Fredrik Lundin, Mats Tullberg
Chronic effects of blast injury on the microvasculature in a transgenic mouse model of Alzheimer’s disease related Aβ amyloidosis
Alexander T. Clark, Eric E. Abrahamson, Matthew M. Harper, Milos D. Ikonomovic
Pericyte, but not astrocyte, hypoxia inducible factor-1 (HIF-1) drives hypoxia-induced vascular permeability in vivo
Julia Baumann, Chih-Chieh Tsao, Shalmali Patkar, Sheng-Fu Huang, Simona Francia, Synnøve Norvoll Magnussen, Max Gassmann, Johannes Vogel, Christina Köster-Hegmann, Omolara O. Ogunshola
Met-RANTES preserves the blood–brain barrier through inhibiting CCR1/SRC/Rac1 pathway after intracerebral hemorrhage in mice
Jun Yan, Weilin Xu, Cameron Lenahan, Lei Huang, Umut Ocak, Jing Wen, Gaigai Li, Wei He, Chensheng Le, John H. Zhang, Ligen Mo, Jiping Tang
Human in silico trials for parametric computational fluid dynamics investigation of cerebrospinal fluid drug delivery: impact of injection location, injection protocol, and physiology
Mohammadreza Khani, Goutham Kumar Reddy Burla, Lucas R. Sass, Ostin N. Arters, Tao Xing, Haiming Wu, Bryn A. Martin
The glymphatic hypothesis: the theory and the evidence
Stephen B. Hladky, Margery A. Barrand
Prolonged culturing of iPSC-derived brain endothelial-like cells is associated with quiescence, downregulation of glycolysis, and resistance to disruption by an Alzheimer’s brain milieu
Lindsey M. Williams, Takashi Fujimoto, Riley R. Weaver, Aric F. Logsdon, Kira M. Evitts, Jessica E. Young, William A. Banks, Michelle A. Erickson
Cerebrospinal fluid biomarkers that reflect clinical symptoms in idiopathic normal pressure hydrocephalus patients
Heikki Lukkarinen, Anna Jeppsson, Carsten Wikkelsö, Kaj Blennow, Henrik Zetterberg, Radu Constantinescu, Anne M. Remes, Sanna-Kaisa Herukka, Mikko Hiltunen, Tuomas Rauramaa, Katarina Nägga, Ville Leinonen, Mats Tullberg
k-Shape clustering for extracting macro-patterns in intracranial pressure signals
Isabel Martinez-Tejada, Casper Schwartz Riedel, Marianne Juhler, Morten Andresen, Jens E. Wilhjelm
CNS endothelial derived extracellular vesicles are biomarkers of active disease in multiple sclerosis
Michael Mazzucco, William Mannheim, Samantha V. Shetty, Jennifer R. Linden
Changes in intrathoracic pressure, not arterial pulsations, exert the greatest effect on tracer influx in the spinal cord
Shinuo Liu, Lynne E. Bilston, Neftali Flores Rodriguez, Courtney Wright, Simon McMullan, Robert Lloyd, Marcus A. Stoodley, Sarah J. Hemley
Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus
Madelene Braun, Caroline Bjurnemark, Woosung Seo, Eva Freyhult, Dag Nyholm, Valter Niemelä, Kaj Blennow, Henrik Zetterberg, David Fällmar, Kim Kultima, Johan Virhammar
Blood–brain barrier dysfunction in l-ornithine induced acute pancreatitis in rats and the direct effect of l-ornithine on cultured brain endothelial cells
Fruzsina R. Walter, András Harazin, Andrea E. Tóth, Szilvia Veszelka, Ana R. Santa-Maria, Lilla Barna, András Kincses, György Biczó, Zsolt Balla, Balázs Kui, József Maléth, László Cervenak, Vilmos Tubak, Ágnes Kittel, Zoltán Rakonczay Jr, Mária A. Deli
Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter
Maria Garcia-Bonilla, Leandro Castaneyra-Ruiz, Sarah Zwick, Michael Talcott, Ayodamola Otun, Albert M. Isaacs, Diego M. Morales, David D. Limbrick Jr., James P. McAllister II
The neurovascular unit in leukodystrophies: towards solving the puzzle
Parand Zarekiani, Henrique Nogueira Pinto, Elly M. Hol, Marianna Bugiani, Helga E. de Vries
Brain barriers virtual: an interim solution or future opportunity?
Brianna M. Holder, Shaina E. Tolan, Kaleb K. Heinrich, Kaitlin C. Miller, Natalie Hudson, Geetika Nehra, Michelle E. Pizzo, Steffen E. Storck, William F. Elmquist, Britta Engelhardt, Irena Loryan, Michal Toborek, Bjoern Bauer, Anika M. S. Hartz, Brandon J. Kim
Sustained glymphatic transport and impaired drainage to the nasal cavity observed in multiciliated cell ciliopathies with hydrocephalus
Yuechuan Xue, Zachary Gursky, Brittany Monte, Sunil Koundal, Xiaodan Liu, Hedok Lee, Tatyana V. Michurina, Kennelia A. Mellanson, Lucy Zhao, Alice Nemajerova, Kristopher T. Kahle, Ken-Ichi Takemaru, Grigori Enikolopov, Natalia I. Peunova, Helene Benveniste
Decreased CSF clearance and increased brain amyloid in Alzheimer’s disease
Yi Li, Henry Rusinek, Tracy Butler, Lidia Glodzik, Elizabeth Pirraglia, John Babich, P. David Mozley, Sadek Nehmeh, Silky Pahlajani, Xiuyuan Wang, Emily B. Tanzi, Liangdong Zhou, Sara Strauss, Roxana O. Carare, Neil Theise, Nobuyuki Okamura, Mony J. de Leon
Dual effect of TAT functionalized DHAH lipid nanoparticles with neurotrophic factors in human BBB and microglia cultures
Sara Hernando, Polyxeni Nikolakopoulou, Dimitrios Voulgaris, Rosa Maria Hernandez, Manoli Igartua, Anna Herland
Parasagittal dural space and cerebrospinal fluid (CSF) flow across the lifespan in healthy adults
Kilian Hett, Colin D. McKnight, Jarrod J. Eisma, Jason Elenberger, Jennifer S. Lindsey, Ciaran M. Considine, Daniel O. Claassen, Manus J. Donahue
Exploring ITM2A as a new potential target for brain delivery
Céline Cegarra, C. Chaves, C. Déon, T. M. Do, B. Dumas, A. Frenzel, P. Kuhn, V. Roudieres, J. C. Guillemot, D. Lesuisse
Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited
Nanna MacAulay, Richard F. Keep, Thomas Zeuthen
Non-coding RNAs in the regulation of blood–brain barrier functions in central nervous system disorders
Ping Sun, Milton H. Hamblin, Ke-Jie Yin
Mechanisms of neuroinflammation in hydrocephalus after intraventricular hemorrhage: a review
Katherine G. Holste, Fan Xia, Fenghui Ye, Richard F. Keep, Guohua Xi
The blood–brain barrier and the neurovascular unit in subarachnoid hemorrhage: molecular events and potential treatments
Peter Solár, Alemeh Zamani, Klaudia Lakatosová, Marek Joukal
Theoretical analysis of wake/sleep changes in brain solute transport suggests a flow of interstitial fluid
John H. Thomas
A novel chronic dural port platform for continuous collection of cerebrospinal fluid and intrathecal drug delivery in free-moving mice
Tsuneo Nakajima, Shuko Takeda, Yuki Ito, Akane Oyama, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto, Hideo Shimizu, Munehisa Shimamura, Hiromi Rakugi, Ryuichi Morishita
Diagnostic biomarker kinetics: how brain-derived biomarkers distribute through the human body, and how this affects their diagnostic significance: the case of S100B
Robert Murcko, Nicola Marchi, Damian Bailey, Damir Janigro
Effects of acute and chronic oxidative stress on the blood–brain barrier in 2D and 3D in vitro models
Tracy D. Chung, Raleigh M. Linville, Zhaobin Guo, Robert Ye, Ria Jha, Gabrielle N. Grifno, Peter C. Searson
Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model
Ravi Teja Kedarasetti, Patrick J. Drew, Francesco Costanzo
White matter changes should not exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery
Carl Snöbohm, Filip Malmberg, Eva Freyhult, Kim Kultima, David Fällmar, Johan Virhammar
Experimental approaches for manipulating choroid plexus epithelial cells
Ahram Jang, Maria K. Lehtinen
Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers
Parvez Alam, Mikkel R. Holst, Line Lauritsen, Janni Nielsen, Simone S. E. Nielsen, Poul Henning Jensen, Jonathan R. Brewer, Daniel E. Otzen, Morten S. Nielsen
Application of blood brain barrier models in pre-clinical assessment of glioblastoma-targeting CAR-T based immunotherapies
Jez Huang, Ying Betty Li, Claudie Charlebois, Tina Nguyen, Ziying Liu, Darin Bloemberg, Ahmed Zafer, Ewa Baumann, Caroline Sodja, Sonia Leclerc, Gwen Fewell, Qing Liu, Balabhaskar Prabhakarpandian, Scott McComb, Danica B. Stanimirovic, Anna Jezierski
Ptpn20 deletion in H-Tx rats enhances phosphorylation of the NKCC1 cotransporter in the choroid plexus: an evidence of genetic risk for hydrocephalus in an experimental study
Hanbing Xu, Masakazu Miyajima, Madoka Nakajima, Ikuko Ogino, Kaito Kawamura, Chihiro Akiba, Chihiro Kamohara, Koichiro Sakamoto, Kostadin Karagiozov, Eri Nakamura, Nobuhiro Tada, Hajime Arai, Akihide Kondo
Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier
Yanyu Li, Chunchun Wang, Liang Zhang, Bing Chen, Yuqian Mo, Jingjing Zhang
Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses
Nina Choublier, Meryam Taghi, Marie-Claude Menet, Morgane Le Gall, Johanna Bruce, Philippe Chafey, François Guillonneau, Amélie Moreau, Claire Denizot, Yannick Parmentier, Samir Nakib, Didier Borderie, Haniaa Bouzinba-Segard, Pierre-Olivier Couraud, Sandrine Bourdoulous, Xavier Declèves
Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF
Ryuta Jomura, Shin-ichi Akanuma, Yoshiyuki Kubo, Masanori Tachikawa, Ken-ichi Hosoya
Effects of fasudil on blood–brain barrier integrity
Kei Sato, Shinsuke Nakagawa, Yoichi Morofuji, Yuki Matsunaga, Takashi Fujimoto, Daisuke Watanabe, Tsuyoshi Izumo, Masami Niwa, Fruzsina R. Walter, Judit P. Vigh, Ana Raquel Santa-Maria, Maria A. Deli, Takayuki Matsuo
Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus
Søren N. Andreassen, Trine L. Toft-Bertelsen, Jonathan H. Wardman, René Villadsen, Nanna MacAulay
Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors
Daniel Dahlberg, Jutta Rummel, Sonia Distante, Gustavo Antonio De Souza, Maria Ekman Stensland, Espen Mariussen, Helge Rootwelt, Øyvind Voie, Bjørnar Hassel
Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping
Yong Zhang, Sabrina Rahman Archie, Yashwardhan Ghanwatkar, Sejal Sharma, Saeideh Nozohouri, Elizabeth Burks, Alexander Mdzinarishvili, Zijuan Liu, Thomas J. Abbruscato
Vascular network expansion, integrity of blood–brain interfaces, and cerebrospinal fluid cytokine concentration during postnatal development in the normal and jaundiced rat
Sandrine Blondel, Nathalie Strazielle, Amel Amara, Rainui Guy, Christine Bain, Alix Rose, Laurent Guibaud, Claudio Tiribelli, Silvia Gazzin, Jean-François Ghersi-Egea
Advances in brain barriers and brain fluids research in 2021: great progress in a time of adversity
Richard F. Keep, Hazel C. Jones, Lester R. Drewes
Regulation of brain iron uptake by apo- and holo-transferrin is dependent on sex and delivery protein
Stephanie L. Baringer, Elizabeth B. Neely, Kondaiah Palsa, Ian A. Simpson, James R. Connor
The impact of genetic manipulation of laminin and integrins at the blood–brain barrier
Sebok K. Halder, Arjun Sapkota, Richard Milner
Gait apraxia evaluation in normal pressure hydrocephalus using inertial sensors. Clinical correlates, ventriculoperitoneal shunt outcomes, and tap-test predictive capacity
Alberto Ferrari, David Milletti, Pierpaolo Palumbo, Giulia Giannini, Sabina Cevoli, Elena Magelli, Luca Albini-Riccioli, Paolo Mantovani, Pietro Cortelli, Lorenzo Chiari, Giorgio Palandri
Cerebrospinal fluid osmolality cannot predict development or surgical outcome of idiopathic normal pressure hydrocephalus
Eva Kjer Oernbo, Annette Buur Steffensen, Hanne Gredal, Helle Harding Poulsen, Nina Rostgaard, Cecilie Holm Rasmussen, Marlene Møller-Nissen, Anja Hviid Simonsen, Steen Gregers Hasselbalch, Marianne Juhler, Nanna MacAulay
Acetazolamide modulates intracranial pressure directly by its action on the cerebrospinal fluid secretion apparatus
Dagne Barbuskaite, Eva K. Oernbo, Jonathan H. Wardman, Trine L. Toft-Bertelsen, Eller Conti, Søren N. Andreassen, Niklas J. Gerkau, Christine R. Rose, Nanna MacAulay
Brain microvascular endothelial cell dysfunction in an isogenic juvenile iPSC model of Huntington’s disease
Raleigh M. Linville, Renée F. Nerenberg, Gabrielle Grifno, Diego Arevalo, Zhaobin Guo, Peter C. Searson
Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders
Markus Herberg Hovd, Espen Mariussen, Hilde Uggerud, Aslan Lashkarivand, Hege Christensen, Geir Ringstad, Per Kristian Eide
Proteomics-based investigation of cerebrovascular molecular mechanisms in cerebral amyloid angiopathy by the FFPE-LMD-PCT-SWATH method
Takumi Handa, Hayate Sasaki, Masaki Takao, Mitsutoshi Tano, Yasuo Uchida
Selective sphingosine-1-phosphate receptor 1 modulator attenuates blood–brain barrier disruption following traumatic brain injury by inhibiting vesicular transcytosis
Yuan Zhang, Lin Wang, Qiuling Pan, Xiaomin Yang, Yunchuan Cao, Jin Yan, Yingwen Wang, Yihao Tao, Runjin Fan, Xiaochuan Sun, Lin Li
Glioblastoma disrupts the ependymal wall and extracellular matrix structures of the subventricular zone
Emily S. Norton, Lauren A. Whaley, María José Ulloa-Navas, Patricia García-Tárraga, Kayleah M. Meneses, Montserrat Lara-Velazquez, Natanael Zarco, Anna Carrano, Alfredo Quiñones-Hinojosa, José Manuel García-Verdugo, Hugo Guerrero-Cázares
Ventricular volume in relation to lumbar CSF levels of amyloid-β 1–42, tau and phosphorylated tau in iNPH, is there a dilution effect?
Simon Lidén, Dan Farahmand, Katarina Laurell
Extracellular vesicles through the blood–brain barrier: a review
Héctor M. Ramos-Zaldívar, Iva Polakovicova, Edison Salas-Huenuleo, Alejandro H. Corvalán, Marcelo J. Kogan, Claudia P. Yefi, Marcelo E. Andia
Antibody indices of infectious pathogens from serum and cerebrospinal fluid in patients with schizophrenia spectrum disorders
Kimon Runge, Agnes Balla, Bernd L. Fiebich, Simon J. Maier, Benjamin Pankratz, Andrea Schlump, Kathrin Nickel, Rick Dersch, Katharina Domschke, Ludger Tebartz van Elst, Dominique Endres
Posthemorrhagic hydrocephalus associates with elevated inflammation and CSF hypersecretion via activation of choroidal transporters
Sara Diana Lolansen, Nina Rostgaard, Dagne Barbuskaite, Tenna Capion, Markus Harboe Olsen, Nicolas H. Norager, Frederik Vilhardt, Søren Norge Andreassen, Trine L. Toft-Bertelsen, Fenghui Ye, Marianne Juhler, Richard F. Keep, Nanna MacAulay
Role of aging in Blood–Brain Barrier dysfunction and susceptibility to SARS-CoV-2 infection: impacts on neurological symptoms of COVID-19
Daniel Adesse, Luis Gladulich, Liandra Alvarez-Rosa, Michele Siqueira, Anne Caroline Marcos, Marialice Heider, Caroline Soares Motta, Silvia Torices, Michal Toborek, Joice Stipursky
A transcriptomic analysis of cerebral microvessels reveals the involvement of Notch1 signaling in endothelial mitochondrial-dysfunction-dependent BBB disruption
Min Joung Lee, Jiebo Zhu, Jong Hun An, Seong Eun Lee, Tae Yeon Kim, Eungseok Oh, Yea Eun Kang, Woosuk Chung, Jun Young Heo
Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure
Eva K. Oernbo, Annette B. Steffensen, Pooya Razzaghi Khamesi, Trine L. Toft-Bertelsen, Dagne Barbuskaite, Frederik Vilhardt, Niklas J. Gerkau, Katerina Tritsaris, Anja H. Simonsen, Sara D. Lolansen, Søren N. Andreassen, Steen G. Hasselbalch, Thomas Zeuthen, Christine R. Rose, Vartan Kurtcuoglu, Nanna MacAulay
Distinct volumetric features of cerebrospinal fluid distribution in idiopathic normal-pressure hydrocephalus and Alzheimer’s disease
Jaehwan Han, Myoung Nam Kim, Ho-Won Lee, Shin Young Jeong, Sang-Woo Lee, Uicheul Yoon, Kyunghun Kang
Mathematical modelling of the CSF system: effects of microstructures and posture on optic nerve subarachnoid space dynamics
Petter Holmlund, Karen-Helene Støverud, Anders Eklund
Microglia-derived CCL2 has a prime role in neocortex neuroinflammation
Mariella Errede, Tiziana Annese, Valentina Petrosino, Giovanna Longo, Francesco Girolamo, Ignazio de Trizio, Antonio d’Amati, Antonio Uccelli, Nicole Kerlero de Rosbo, Daniela Virgintino
Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1
Trine L. Toft-Bertelsen, Dagne Barbuskaite, Eva Kjer Heerfordt, Sara Diana Lolansen, Søren Norge Andreassen, Nina Rostgaard, Markus Harboe Olsen, Nicolas H. Norager, Tenna Capion, Martin Fredensborg Rath, Marianne Juhler, Nanna MacAulay
Activation of NMDA receptors in brain endothelial cells increases transcellular permeability
Kyu-Sung Kim, Min Tae Jeon, Eun Seon Kim, Chan Hee Lee, Do-Geun Kim
In vivo assessment of Lewy body and beta-amyloid copathologies in idiopathic normal pressure hydrocephalus: prevalence and associations with clinical features and surgery outcome
Giulia Giannini, Simone Baiardi, Sofia Dellavalle, Corrado Zenesini, Sabina Cevoli, Nils Danner, Henna-Kaisa Jyrkkänen, Marcello Rossi, Barbara Polischi, Corinne Quadalti, Camilla Stefanini, Pietro Cortelli, David Milletti, Sanna-Kaisa Herukka, Giorgio Palandri, Ville Leinonen, Piero Parchi
Characterization of passive permeability after low intensity focused ultrasound mediated blood–brain barrier disruption in a preclinical model
Tasneem A. Arsiwala, Samuel A. Sprowls, Kathryn E. Blethen, Ross A. Fladeland, Cullen P. Wolford, Brooke N. Kielkowski, Morgan J. Glass, Peng Wang, Olivia Wilson, Jeffrey S. Carpenter, Manish Ranjan, Victor Finomore, Ali Rezai, Paul R. Lockman
ROS attenuates TET2-dependent ZO-1 epigenetic expression in cerebral vascular endothelial cells
Lan Wang, Bei Mao, Keyang Fan, Renqiang Sun, Jialong Zhang, Huazheng Liang, Ying Liu
Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome
Ali Ehsan Sifat, Sabrina Rahman Archie, Saeideh Nozohouri, Heidi Villalba, Yong Zhang, Sejal Sharma, Yashwardhan Ghanwatkar, Bhuvaneshwar Vaidya, David Mara, Luca Cucullo, Thomas J. Abbruscato
The choroid plexus and its role in the pathogenesis of neurological infections
Derick Thompson, Catherine A. Brissette, John A. Watt
Mucopolysaccharidoses and the blood–brain barrier
Onur Sahin, Hannah P. Thompson, Grant W. Goodman, Jun Li, Akihiko Urayama
Nuclear receptor ligand screening in an iPSC-derived in vitro blood–brain barrier model identifies new contributors to leptin transport
Yajuan Shi, Hyosung Kim, Catherine A. Hamann, Elizabeth M. Rhea, Jonathan M. Brunger, Ethan S. Lippmann
The effect of A1 and A2 reactive astrocyte expression on hydrocephalus shunt failure
Fatemeh Khodadadei, Rooshan Arshad, Diego M. Morales, Jacob Gluski, Neena I. Marupudi, James P. McAllister II, David D. Limbrick Jr., Carolyn A. Harris
VHHs as tools for therapeutic protein delivery to the central nervous system
Yessica Wouters, Tom Jaspers, Laura Rué, Lutgarde Serneels, Bart De Strooper, Maarten Dewilde
The choroid plexus: a door between the blood and the brain for tissue-type plasminogen activator
Vincent Zuba, Jonathane Furon, Mathys Bellemain-Sagnard, Sara Martinez de Lizarrondo, Laurent Lebouvier, Marina Rubio, Yannick Hommet, Maxime Gauberti, Denis Vivien, Carine Ali
Development of a multicellular in vitro model of the meningeal blood-CSF barrier to study Neisseria meningitidis infection
Leo M. Endres, Marvin Jungblut, Mustafa Divyapicigil, Markus Sauer, Christian Stigloher, Myron Christodoulides, Brandon J. Kim, Alexandra Schubert-Unkmeir
Impact of age on the cerebrospinal fluid spaces: high-convexity and medial subarachnoid spaces decrease with age
Yosuke Hidaka, Mamoru Hashimoto, Takashi Suehiro, Ryuji Fukuhara, Tomohisa Ishikawa, Naoko Tsunoda, Asuka Koyama, Kazuki Honda, Yusuke Miyagawa, Kazuhiro Yoshiura, Shuken Boku, Kazunari Ishii, Manabu Ikeda, Minoru Takebayashi
Correction to: The choroid plexus: A door between the blood and the brain for tissue-type plasminogen activator
Vincent Zuba, Jonathane Furon, Mathys Bellemain-Sagnard, Sara Martinez de Lazarrondo, Laurent Lebouvier, Marina Rubio, Yannick Hommet, Maxime Gauberti, Denis Vivien, Carine Ali
Human intracranial pulsatility during the cardiac cycle: a computational modelling framework
Marius Causemann, Vegard Vinje, Marie E. Rognes
Evaluation of diurnal and postural intracranial pressure employing telemetric monitoring in idiopathic intracranial hypertension
James L Mitchell, Rebecca Buckham, Hannah Lyons, Jessica K Walker, Andreas Yiangou, Matilde Sassani, Mark Thaller, Olivia Grech, Zerin Alimajstorovic, Marianne Julher, Georgios Tsermoulas, Kristian Brock, Susan P Mollan, Alexandra J Sinclair
Transgenic animal models to explore and modulate the blood brain and blood retinal barriers of the CNS
Andreia Goncalves, David A. Antonetti
Three-dimensional microenvironment regulates gene expression, function, and tight junction dynamics of iPSC-derived blood–brain barrier microvessels
Raleigh M. Linville, Matthew B. Sklar, Gabrielle N. Grifno, Renée F. Nerenberg, Justin Zhou, Robert Ye, Jackson G. DeStefano, Zhaobin Guo, Ria Jha, John J. Jamieson, Nan Zhao, Peter C. Searson
Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer´s disease and type two diabetes
Maria Vargas-Soria, Juan Jose Ramos-Rodriguez, Angel del Marco, Carmen Hierro-Bujalance, Maria Jose Carranza-Naval, Maria Calvo-Rodriguez, Susanne J. van Veluw, Alan W. Stitt, Rafael Simó, Brian J. Bacskai, Carmen Infante-Garcia, Monica Garcia-Alloza
The effect of shunt surgery on corticospinal excitability in idiopathic normal pressure hydrocephalus: a transcranial magnetic stimulation study
Jani Sirkka, Laura Säisänen, Petro Julkunen, Mervi Könönen, Elisa Kallioniemi, Ville Leinonen, Nils Danner
Age dependent contribution of entry via the CSF to the overall brain entry of small and large hydrophilic markers
Fiona Qiu, Yifan Huang, Norman R. Saunders, Mark D. Habgood, Katarzyna M. Dziegielewska
Correction: Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping
Yong Zhang, Sabrina Rahman Archie, Yashwardhan Ghanwatkar, Sejal Sharma, Saeideh Nozohouri, Elizabeth Burks, Alexander Mdzinarishvili, Zijuan Liu, Thomas J. Abbruscato
Novel localization of folate transport systems in the murine central nervous system
Vishal Sangha, Md. Tozammel Hoque, Jeffrey T. Henderson, Reina Bendayan
Evaluation of CSF albumin quotient in neuronal surface antibody-associated autoimmune encephalitis
Qi-Lun Lai, Meng-Ting Cai, Yang Zheng, Gao-Li Fang, Bing-Qing Du, Chun-Hong Shen, Jia-Jia Wang, Qin-Jie Weng, Yin-Xi Zhang
Transcriptomic analysis of a 3D blood–brain barrier model exposed to disturbed fluid flow
Nesrine Bouhrira, Brandon J. DeOre, Kiet A. Tran, Peter A. Galie
Modulation of striatal glutamatergic, dopaminergic and cholinergic neurotransmission pathways concomitant with motor disturbance in rats with kaolin-induced hydrocephalus
Li-Jin Chen, Jeng-Rung Chen, Guo-Fang Tseng
Is plasma amyloid-β 1–42/1–40 a better biomarker for Alzheimer’s disease than AβX–42/X–40?
Hans-Wolfgang Klafki, Barbara Morgado, Oliver Wirths, Olaf Jahn, Chris Bauer, Hermann Esselmann, Johannes Schuchhardt, Jens Wiltfang
Exogenous laminin exhibits a unique vascular pattern in the brain via binding to dystroglycan and integrins
Jingsong Ruan, Karen K. McKee, Peter D. Yurchenco, Yao Yao
Induced pluripotent stem cell-derived cells model brain microvascular endothelial cell glucose metabolism
Callie M. Weber, Bilal Moiz, Sophia M. Zic, Viviana Alpízar Vargas, Andrew Li, Alisa Morss Clyne
Brain pharmacokinetics of mono- and bispecific amyloid-β antibodies in wild-type and Alzheimer’s disease mice measured by high cut-off microdialysis
Ulrika Julku, Mengfei Xiong, Elin Wik, Sahar Roshanbin, Dag Sehlin, Stina Syvänen
Blood and cerebrospinal fluid flow oscillations measured with real-time phase-contrast MRI: breathing mode matters
Maria Marcella Laganà, Sonia Di Tella, Francesca Ferrari, Laura Pelizzari, Marta Cazzoli, Noam Alperin, Ning Jin, Domenico Zacà, Giuseppe Baselli, Francesca Baglio
Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies
Guojun Liu, Antonio Ladrón-de-Guevara, Yara Izhiman, Maiken Nedergaard, Ting Du
Bacterial ribosomal RNA detection in cerebrospinal fluid using a viromics approach
Cormac M. Kinsella, Arthur W. D. Edridge, Ingeborg E. van Zeggeren, Martin Deijs, Diederik van de Beek, Matthijs C. Brouwer, Lia van der Hoek
The new insight into the inflammatory response following focused ultrasound-mediated blood–brain barrier disruption
Hyo Jin Choi, Mun Han, Hyeon Seo, Chan Yuk Park, Eun-Hee Lee, Juyoung Park