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Gastric Cancer

Ausgabe 6/2019

Inhalt (26 Artikel)

Original Article

Genetic variations associated with telomere length confer risk of gastric cardia adenocarcinoma

Nasha Zhang, Yan Zheng, Jie Liu, Tiansui Lei, Yeyang Xu, Ming Yang

Original Article

The role of FBXW7, a cell-cycle regulator, as a predictive marker of recurrence of gastrointestinal stromal tumors

Yuki Koga, Masaaki Iwatsuki, Kohei Yamashita, Yuki Kiyozumi, Junji Kurashige, Toshiro Masuda, Kojiro Eto, Shiro Iwagami, Kazuto Harada, Takatsugu Ishimoto, Yoshifumi Baba, Naoya Yoshida, Nobutomo Miyanari, Hiroshi Takamori, Jaffer A. Ajani, Hideo Baba

Original Article

DNA methylation genome-wide analysis in remnant and primary gastric cancers

Kiichi Sugimoto, Tomoaki Ito, Alicia Hulbert, Chen Chen, Hajime Orita, Masahiro Maeda, Hiroshi Moro, Takeo Fukagawa, Toshikazu Ushijima, Hitoshi Katai, Ryo Wada, Koichi Sato, Kazuhiro Sakamoto, Wayne Yu, Michael Considine, Leslie Cope, Malcolm V. Brock

Original Article

A polymorphism within the mismatch repair gene predicts prognosis and adjuvant chemotherapy benefit in gastric cancer

Xiaohui Zhao, Dongfang Dai, Xiaoqin Li, Bo Shen, Xiaofeng Chen, Yongqian Shu, Deqiang Wang

Open Access Original Article

The expression of the insulin receptor in gastric cancer correlates with the HER2 status and may have putative therapeutic implications

Steffen M. Heckl, Viva Wiesener, Hans-Michael Behrens, Dita Ulase, Sandra Krüger, Christoph Röcken

Original Article

The levels of SYT13 and CEA mRNAs in peritoneal lavages predict the peritoneal recurrence of gastric cancer

Koki Nakanishi, Mitsuro Kanda, Shinichi Umeda, Chie Tanaka, Daisuke Kobayashi, Masamichi Hayashi, Suguru Yamada, Yasuhiro Kodera

Original Article

Inhibiting casein kinase 2 overcomes paclitaxel resistance in gastric cancer

Minkyu Jung, Kyu Hyun Park, Hyun Myong Kim, Tae Soo Kim, Xianglan Zhang, Sun-Mi Park, Seung-Hoon Beom, Hyo Song Kim, Jae-Ho Cheong, Hyun Cheol Chung, John Soong, Shu-chuan Lin, Sun Young Rha

Original Article

Differences in immune contextures among different molecular subtypes of gastric cancer and their prognostic impact

Joo Yeon Kim, Woo Gyeong Kim, Chae Hwa Kwon, Do Youn Park

Original Article

Risk stratification for lymph node metastasis using Epstein–Barr virus status in submucosal invasive (pT1) gastric cancer without lymphovascular invasion: a multicenter observational study

Hiroki Osumi, Hiroshi Kawachi, Katsuyuki Murai, Kimihide Kusafuka, Shuntaro Inoue, Masaki Kitamura, Toshiyuki Yoshio, Naomi Kakusima, Ryu Ishihara, Hiroyuki Ono, Noriko Yamamoto, Takashi Sugino, Shinichi Nakatsuka, Satoshi Ida, Souya Nunobe, Etsuro Bando, Takeshi Omori, Kengo Takeuchi, Junko Fujisaki

Open Access Original Article

Hepatoid adenocarcinoma of the stomach: a unique subgroup with distinct clinicopathological and molecular features

Yakun Wang, Li Sun, Zhongwu Li, Jing Gao, Sai Ge, Cheng Zhang, Jiajia Yuan, Xicheng Wang, Jian Li, Zhihao Lu, Jifang Gong, Ming Lu, Jun Zhou, Zhi Peng, Lin Shen, Xiaotian Zhang

Open Access Original Article

KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study

Lindsay C. Hewitt, Yuichi Saito, Tan Wang, Yoko Matsuda, Jan Oosting, Arnaldo N. S. Silva, Hayley L. Slaney, Veerle Melotte, Gordon Hutchins, Patrick Tan, Takaki Yoshikawa, Tomio Arai, Heike I. Grabsch

Correction

Correction to: KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study

Lindsay C. Hewitt, Yuichi Saito, Tan Wang, Yoko Matsuda, Jan Oosting, Arnaldo N. S. Silva, Hayley L. Slaney, Veerle Melotte, Gordon Hutchins, Patrick Tan, Takaki Yoshikawa, Tomio Arai, Heike I. Grabsch

Original Article

A phase I/II study of poziotinib combined with paclitaxel and trastuzumab in patients with HER2-positive advanced gastric cancer

Tae-Yong Kim, Hye Sook Han, Keun-Wook Lee, Dae Young Zang, Sun Young Rha, Young Iee Park, Jin-Soo Kim, Kyung-Hun Lee, Se Hoon Park, Eun-Kee Song, Soo-A Jung, NaMi Lee, Yeul Hong Kim, Jae Yong Cho, Yung-Jue Bang

Original Article

Delay in initiation of postoperative adjuvant chemotherapy with S-1 monotherapy and prognosis for gastric cancer patients: analysis of a multi-institutional dataset

Koki Nakanishi, Mitsuro Kanda, Seiji Ito, Yoshinari Mochizuki, Hitoshi Teramoto, Kiyoshi Ishigure, Toshifumi Murai, Takahiro Asada, Akiharu Ishiyama, Hidenobu Matsushita, Chie Tanaka, Daisuke Kobayashi, Michitaka Fujiwara, Kenta Murotani, Yasuhiro Kodera

Original Article

The efficacy of treatment options for patients with gastric cancer and peritoneal metastasis

Beate Rau, Andreas Brandl, Peter Thuss-Patience, Fabian Bergner, Wieland Raue, Alexander Arnold, David Horst, Johann Pratschke, Matthias Biebl

Original Article

Multicenter phase II study of trastuzumab with S-1 plus oxaliplatin for chemotherapy-naïve, HER2-positive advanced gastric cancer

Daisuke Takahari, Keisho Chin, Naoki Ishizuka, Atsuo Takashima, Keiko Minashi, Shigenori Kadowaki, Tomohiro Nishina, Takako Eguchi Nakajima, Kenji Amagai, Nozomu Machida, Masahiro Goto, Keisei Taku, Takeru Wakatsuki, Hirokazu Shoji, Shuichi Hironaka, Narikazu Boku, Kensei Yamaguchi

Original Article

Should pylorus-preserving gastrectomy be performed for overweight/obese patients with gastric cancer?

Masahiro Tsujiura, Naoki Hiki, Manabu Ohashi, Souya Nunobe, Koshi Kumagai, Satoshi Ida, Takuma Ohashi, Takeshi Sano, Toshiharu Yamaguchi

Original Article

Timing and site-specific trends of recurrence in patients with pathological stage II or III gastric cancer after curative gastrectomy followed by adjuvant S-1 monotherapy

Ryo Takahashi, Manabu Ohashi, Yosuke Kano, Satoshi Ida, Koshi Kumagai, Souya Nunobe, Keisho Chin, Kensei Yamaguchi, Masato Nagino, Takeshi Sano, Naoki Hiki

Open Access Original Article

Recurrence after preoperative chemotherapy and surgery for gastric adenocarcinoma: a multicenter study

I. Mokadem, W. P. M. Dijksterhuis, M. van Putten, L. Heuthorst, J. M. de Vos-Geelen, N. Haj Mohammad, G. A. P. Nieuwenhuijzen, H. W. M. van Laarhoven, R. H. A. Verhoeven

Original Article

Does neoadjuvant chemotherapy cancel out the negative survival impact induced by surgical complications after gastrectomy?

Masato Hayashi, Takaki Yoshikawa, Masahiro Yura, Sho Otsuki, Yukinori Yamagata, Shinji Morita, Hitoshi Katai, Toshirou Nishida

Original Article

Conversion gastrectomy for stage IV unresectable gastric cancer: a GIRCG retrospective cohort study

Leonardo Solaini, Silvia Ministrini, Maria Bencivenga, Alessia D’Ignazio, Elisabetta Marino, Chiara Cipollari, Beatrice Molteni, Gianni Mura, Daniele Marrelli, Luigina Graziosi, Franco Roviello, Giovanni De Manzoni, Guido A. M. Tiberio, Paolo Morgagni

Case Report

Different phenotypes of gastric fundic gland polyposis and cancer in patients with familial adenomatous polyposis depending on Helicobacter pylori infection

Yasuhiro Mitsui, Ayaka Miyoshi, Koichi Okamoto, Naoki Muguruma, Jinsei Miyoshi, Kumiko Tanaka, Shinji Kitamura, Hiroshi Miyamoto, Yasushi Sato, Yoshimi Bando, Joji Shunto, Hidetaka Eguchi, Yasushi Okazaki, Hideyuki Ishida, Tetsuji Takayama

Short Communication

An integrated analysis of two phase II trials (JCOG0001 and JCOG0405) of preoperative chemotherapy followed by D3 gastrectomy for gastric cancer with extensive lymph node metastasis

Hiroshi Katayama, Akira Tsuburaya, Junki Mizusawa, Kenichi Nakamura, Hitoshi Katai, Hiroshi Imamura, Atsushi Nashimoto, Norimasa Fukushima, Takeshi Sano, Mitsuru Sasako

Letter to the Editor

Always randomize as late as possible

Erik van Werkhoven, Parvin Tajik, Patrick M. Bossuyt

Letter to the Editor

Report about the present condition of Billroth’s stomach specimens

Hiroshi Sato, Hirokazu Noshiro

Update Chirurgie

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S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.