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Zeitschrift

Investigational New Drugs

Investigational New Drugs 1/2009

Ausgabe 1/2009

Inhaltsverzeichnis ( 11 Artikel )

01.02.2009 | PRECLINICAL STUDIES | Ausgabe 1/2009

Antitumor activity of a novel EGFR tyrosine kinase inhibitor against human lung carcinoma in vitro and in vivo

Xishan Xiong, Lili Fu, Li Wang, Houan Cai, Lin Li, Hualiang Jiang, Wenhu Duan, Changlin Mei

01.02.2009 | PRECLINICAL STUDIES | Ausgabe 1/2009

Brazilian marine sponge Polymastia janeirensis induces apoptotic cell death in human U138MG glioma cell line, but not in a normal cell culture

Mario Luiz Conte da Frota Jr, Elizandra Braganhol, Andrés Delgado Canedo, Fabio Klamt, Miriam Anders Apel, Beatriz Mothes, Cléa Lerner, Ana Maria Oliveira Battastini, Amélia Teresinha Henriques, José Cláudio Fonseca Moreira

01.02.2009 | PRECLINICAL STUDIES | Ausgabe 1/2009

Effect of morin on tissue lipid peroxidation and antioxidant status in 1, 2-dimethylhydrazine induced experimental colon carcinogenesis

Vennila Sreedharan, Karthik Kumar Venkatachalam, Nalini Namasivayam

01.02.2009 | PRECLINICAL STUDIES | Ausgabe 1/2009

The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib

Roos L. Oostendorp, Tessa Buckle, Jos H. Beijnen, Olaf van Tellingen, Jan H. M. Schellens

01.02.2009 | PRECLINICAL STUDIES | Ausgabe 1/2009

Development of water soluble derivatives of cis-3, 4′, 5-trimethoxy-3′-aminostilbene for optimization and use in cancer therapy

David E. Durrant, Joanna Richards, Ashutosh Tripathi, Glen E. Kellogg, Paolo Marchetti, Marco Eleopra, Giuseppina Grisolia, Daniele Simoni, Ray M. Lee

01.02.2009 | PHASE I STUDIES | Ausgabe 1/2009

A phase I study of bortezomib, etoposide and carboplatin in patients with advanced solid tumors refractory to standard therapy

Christopher Lieu, Laura Chow, A. Scott Pierson, S. Gail Eckhardt, Cindy L. O’Bryant, Mark Morrow, Zung Vu Tran, John J. Wright, Lia Gore

01.02.2009 | PHASE I STUDIES | Ausgabe 1/2009

A phase I trial of PTK787/ZK222584 in combination with pemetrexed and cisplatin in patients with advanced solid tumors

Sunil Sharma, Burgess Freeman, Jeanette Turner, James Symanowski, Phillip Manno, William Berg, Nicholas Vogelzang

01.02.2009 | PHASE II STUDIES | Ausgabe 1/2009

Docetaxel and epirubicin salvage regimen in relapsed anthracycline-sensitive metastatic breast cancer patients after anthracycline-containing adjuvant therapy

Jae Hong Seo, Hwa Jung Sung, Kyong Hwa Park, In Keun Choi, Sang Cheul Oh, Sang Won Shin, Yeul Hong Kim, Jun Suk Kim, Ae-Ree Kim, Jae-Bok Lee, Bum Hwan Koo

01.02.2009 | PHASE II STUDIES | Ausgabe 1/2009

A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer

Hedy Lee Kindler, Howard A. Burris III, Alan B. Sandler, Ira Anton Oliff

01.02.2009 | SHORT REPORT | Ausgabe 1/2009

Colonic pneumatosis and intestinal perforations with sunitinib treatment for renal cell carcinoma

Thomas W. Flaig, Fernando J. Kim, Francisco G. La Rosa, Kathryn Breaker, Jonathan Schoen, Paul D. Russ

01.02.2009 | SHORT REPORT | Ausgabe 1/2009

Inhibition of protein synthesis by imexon reduces HIF-1α expression in normoxic and hypoxic pancreatic cancer cells

Betty K. Samulitis, Terry H. Landowski, Robert T. Dorr

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