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Zeitschrift

Journal of Neuroinflammation

Journal of Neuroinflammation 1/2017

Ausgabe 1/2017

Inhaltsverzeichnis ( 262 Artikel )

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

Charbel Moussa, Michaeline Hebron, Xu Huang, Jaeil Ahn, Robert A. Rissman, Paul S. Aisen, R. Scott Turner

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

E. Soemirien Kasanmoentalib, Mercedes Valls Seron, Bart Ferwerda, Michael W. Tanck, Aeilko H. Zwinderman, Frank Baas, Arie van der Ende, Matthijs C. Brouwer, Diederik van de Beek

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide

Ester Bonfill-Teixidor, Amaia Otxoa-de-Amezaga, Miriam Font-Nieves, M. Glòria Sans-Fons, Anna M. Planas

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator

Sven Micklisch, Yuchen Lin, Saskia Jacob, Marcus Karlstetter, Katharina Dannhausen, Prasad Dasari, Monika von der Heide, Hans-Martin Dahse, Lisa Schmölz, Felix Grassmann, Medhanie Alene, Sascha Fauser, Harald Neumann, Stefan Lorkowski, Diana Pauly, Bernhard H. Weber, Antonia M. Joussen, Thomas Langmann, Peter F. Zipfel, Christine Skerka

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Resolvin RvD2 reduces hypothalamic inflammation and rescues mice from diet-induced obesity

Livia B. Pascoal, Bruna Bombassaro, Albina F. Ramalho, Andressa Coope, Rodrigo F. Moura, Felipe Correa-da-Silva, Leticia Ignacio-Souza, Daniela Razolli, Diogo de Oliveira, Rodrigo Catharino, Licio A. Velloso

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Enhanced neuroinflammation mediated by DNA methylation of the glucocorticoid receptor triggers cognitive dysfunction after sevoflurane anesthesia in adult rats subjected to maternal separation during the neonatal period

Yangzi Zhu, Yu Wang, Rui Yao, Ting Hao, Junli Cao, He Huang, Liwei Wang, Yuqing Wu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism

Mikiei Tanaka, Sean Moran, Jie Wen, Kwame Affram, Tinghua Chen, Aviva J. Symes, Yumin Zhang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microglial activation in Parkinson’s disease using [18F]-FEPPA

Christine Ghadery, Yuko Koshimori, Sarah Coakeley, Madeleine Harris, Pablo Rusjan, Jinhee Kim, Sylvain Houle, Antonio P. Strafella

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Absence of system xc − on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis

Ellen Merckx, Giulia Albertini, Magdalena Paterka, Cathy Jensen, Philipp Albrecht, Michael Dietrich, Joeri Van Liefferinge, Eduard Bentea, Lise Verbruggen, Thomas Demuyser, Lauren Deneyer, Jan Lewerenz, Geert van Loo, Jacques De Keyser, Hideyo Sato, Pamela Maher, Axel Methner, Ann Massie

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Inflammation in epileptogenesis after traumatic brain injury

Kyria M. Webster, Mujun Sun, Peter Crack, Terence J. O’Brien, Sandy R. Shultz, Bridgette D. Semple

01.12.2017 | Research | Ausgabe 1/2017 Open Access

BAFF Index and CXCL13 levels in the cerebrospinal fluid associate respectively with intrathecal IgG synthesis and cortical atrophy in multiple sclerosis at clinical onset

M. Puthenparampil, L. Federle, S. Miante, A. Zito, E. Toffanin, S. Ruggero, M. Ermani, S. Pravato, D. Poggiali, P. Perini, F. Rinaldi, P. Gallo

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Genetic effect of interleukin-1 beta (C-511T) polymorphism on the structural covariance network and white matter integrity in Alzheimer’s disease

Chi-Wei Huang, Shih-Wei Hsu, Shih-Jen Tsai, Nai-Ching Chen, Mu-En Liu, Chen-Chang Lee, Shu-Hua Huang, Weng-Neng Chang, Ya-Ting Chang, Wan-Chen Tsai, Chiung-Chih Chang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Activation of human B cells negatively regulates TGF-β1 production

Nicolas Molnarfi, Kristbjörg Bjarnadóttir, Mahdia Benkhoucha, Catherine Juillard, Patrice H. Lalive

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration

Lei Zhao, Jun Li, Yingmei Fu, Mengxue Zhang, Bowen Wang, Jonathan Ouellette, Pawan K. Shahi, Bikash R. Pattnaik, Jyoti J. Watters, Wai T. Wong, Lian-Wang Guo

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Everolimus is better than rapamycin in attenuating neuroinflammation in kainic acid-induced seizures

Ming-Tao Yang, Yi-Chin Lin, Whae-Hong Ho, Chao-Lin Liu, Wang-Tso Lee

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Interleukin-1 as a mediator of fatigue in disease: a narrative review

Megan E. Roerink, Marieke E. van der Schaaf, Charles A. Dinarello, Hans Knoop, Jos W. M. van der Meer

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Acetaminophen attenuates lipopolysaccharide-induced cognitive impairment through antioxidant activity

Wei-Xing Zhao, Jun-Han Zhang, Jiang-Bei Cao, Wei Wang, Dong-Xin Wang, Xiao-Ying Zhang, Jun Yu, Yong-Yi Zhang, You-Zhi Zhang, Wei-Dong Mi

01.12.2017 | Short report | Ausgabe 1/2017 Open Access

Blocking of platelet glycoprotein receptor Ib reduces “thrombo-inflammation” in mice with acute ischemic stroke

Michael K. Schuhmann, Josua Guthmann, Guido Stoll, Bernhard Nieswandt, Peter Kraft, Christoph Kleinschnitz

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Rab32 connects ER stress to mitochondrial defects in multiple sclerosis

Yohannes Haile, Xiaodan Deng, Carolina Ortiz-Sandoval, Nasser Tahbaz, Aleksandra Janowicz, Jian-Qiang Lu, Bradley J. Kerr, Nicholas J. Gutowski, Janet E. Holley, Paul Eggleton, Fabrizio Giuliani, Thomas Simmen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Th17-skewed immune response and cluster of differentiation 40 ligand expression in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis

Jessica Freundt-Revilla, Arianna Maiolini, Regina Carlson, Martin Beyerbach, Kai Rentmeister, Thomas Flegel, Andrea Fischer, Andrea Tipold

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Cerebral ischemic damage in diabetes: an inflammatory perspective

Vibha Shukla, Akhalesh Kumar Shakya, Miguel A. Perez-Pinzon, Kunjan R. Dave

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7

Leon G. Coleman Jr, Jian Zou, Fulton T. Crews

01.12.2017 | Research | Ausgabe 1/2017 Open Access

HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis

Jadwiga Nitkiewicz, Alejandra Borjabad, Susan Morgello, Jacinta Murray, Wei Chao, Luni Emdad, Paul B. Fisher, Mary Jane Potash, David J. Volsky

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Aging and amyloid β oligomers enhance TLR4 expression, LPS-induced Ca2+ responses, and neuron cell death in cultured rat hippocampal neurons

María Calvo-Rodríguez, Carmen de la Fuente, Mónica García-Durillo, Carmen García-Rodríguez, Carlos Villalobos, Lucía Núñez

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid

Soraya Wilke Saliba, Erica Leandro Marciano Vieira, Rebeca Priscila de Melo Santos, Eduardo Candelario-Jalil, Bernd L. Fiebich, Luciene Bruno Vieira, Antonio Lucio Teixeira, Antonio Carlos Pinheiro de Oliveira

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin

Fernando Bartolome, Desiree Antequera, Eva Tavares, Consuelo Pascual, Rosario Maldonado, Antoni Camins, Eva Carro

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Intrathecal Th17- and B cell-associated cytokine and chemokine responses in relation to clinical outcome in Lyme neuroborreliosis: a large retrospective study

Paula Gyllemark, Pia Forsberg, Jan Ernerudh, Anna J. Henningsson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effects of dexamethasone and meloxicam on Borrelia burgdorferi-induced inflammation in glial and neuronal cells of the central nervous system

Geeta Ramesh, Alejandra N. Martinez, Dale S. Martin, Mario T. Philipp

01.12.2017 | Research | Ausgabe 1/2017 Open Access

IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking

Anthony J. Carlos, Liqi Tong, G. Aleph Prieto, Carl W. Cotman

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Cytotoxic T cells modulate inflammation and endogenous opioid analgesia in chronic arthritis

Uta Baddack-Werncke, Melanie Busch-Dienstfertig, Sara González-Rodríguez, Santhosh Chandar Maddila, Jenny Grobe, Martin Lipp, Christoph Stein, Gerd Müller

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis

Catherine W. M. Ong, Przemyslaw J. Pabisiak, Sara Brilha, Poonam Singh, Federico Roncaroli, Paul T. Elkington, Jon S. Friedland

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Combined effect of BCG vaccination and enriched environment promote neurogenesis and spatial cognition via a shift in meningeal macrophage M2 polarization

Fangfang Qi, Zejie Zuo, Junhua Yang, Saisai Hu, Yang Yang, Qunfang Yuan, Juntao Zou, Kaihua Guo, Zhibin Yao

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Regulatory role of cytosolic phospholipase A2 alpha in the induction of CD40 in microglia

Yafa Fetfet Malada-Edelstein, Nurit Hadad, Rachel Levy

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia

Joanna Jaworska, Malgorzata Ziemka-Nalecz, Joanna Sypecka, Teresa Zalewska

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: SDF1 in the dorsal corticospinal tract promotes CXCR4+ cell migration after spinal cord injury

Vicki M. Tysseling, Divakar S. Mithal, Vibhu Sahni, Derin Birch, Hosung Jung, Richard J. Miller, John A. Kessler

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype

Jie Wu, Liang Sun, Haiying Li, Haitao Shen, Weiwei Zhai, Zhengquan Yu, Gang Chen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Aprepitant limits in vivo neuroinflammatory responses in a rhesus model of Lyme neuroborreliosis

Alejandra N. Martinez, Amanda R. Burmeister, Geeta Ramesh, Lara Doyle-Meyers, Ian Marriott, Mario T. Philipp

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microglia P2Y6 receptor is related to Parkinson’s disease through neuroinflammatory process

Xiaodong Yang, Yue Lou, Guidong Liu, Xueping Wang, Yiwei Qian, Jianqing Ding, Shengdi Chen, Qin Xiao

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

Sarah Hopp, Marc W. Nolte, Christian Stetter, Christoph Kleinschnitz, Anna-Leena Sirén, Christiane Albert-Weissenberger

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study

Gabriele Farina, Roberta Magliozzi, Marco Pitteri, Richard Reynolds, Stefania Rossi, Alberto Gajofatto, Maria Donata Benedetti, Francesco Facchiano, Salvatore Monaco, Massimiliano Calabrese

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Fingolimod additionally acts as immunomodulator focused on the innate immune system beyond its prominent effects on lymphocyte recirculation

Katja Thomas, Tony Sehr, Undine Proschmann, Francisco Alejandro Rodriguez-Leal, Rocco Haase, Tjalf Ziemssen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Peripheral blood mononuclear cells from neovascular age-related macular degeneration patients produce higher levels of chemokines CCL2 (MCP-1) and CXCL8 (IL-8)

Judith Lechner, Mei Chen, Ruth E. Hogg, Levente Toth, Giuliana Silvestri, Usha Chakravarthy, Heping Xu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Zika virus infection of cellular components of the blood-retinal barriers: implications for viral associated congenital ocular disease

Tracoyia Roach, Donald J. Alcendor

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Systemic pro-inflammatory cytokine status following therapeutic hypothermia in a piglet hypoxia-ischemia model

Eridan Rocha-Ferreira, Dorottya Kelen, Stuart Faulkner, Kevin D. Broad, Manigandan Chandrasekaran, Áron Kerenyi, Takenori Kato, Alan Bainbridge, Xavier Golay, Mark Sullivan, Boris W. Kramer, Nicola J. Robertson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Molecular imaging of nestin in neuroinflammatory conditions reveals marked signal induction in activated microglia

Senthil Krishnasamy, Yuan-Cheng Weng, Sai Sampath Thammisetty, Daniel Phaneuf, Melanie Lalancette-Hebert, Jasna Kriz

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Pleiotrophin regulates microglia-mediated neuroinflammation

Rosalía Fernández-Calle, Marta Vicente-Rodríguez, Esther Gramage, Jimena Pita, Carmen Pérez-García, Marcel Ferrer-Alcón, María Uribarri, María P. Ramos, Gonzalo Herradón

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury

Alok Kumar, Bogdan A. Stoica, David J. Loane, Ming Yang, Gelareh Abulwerdi, Niaz Khan, Asit Kumar, Stephen R. Thom, Alan I. Faden

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain

Maria I. Fonseca, Shu-Hui Chu, Michael X. Hernandez, Melody J. Fang, Lila Modarresi, Pooja Selvan, Grant R. MacGregor, Andrea J. Tenner

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Astrocyte-specific overexpressed gene signatures in response to methamphetamine exposure in vitro

Nikki Bortell, Liana Basova, Svetlana Semenova, Howard S. Fox, Timothy Ravasi, Maria Cecilia G. Marcondes

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Enhanced susceptibility of triple transgenic Alzheimer’s disease (3xTg-AD) mice to acute infection

Rebecca Montacute, Kerry Foley, Ruth Forman, Kathryn Jane Else, Sheena Margaret Cruickshank, Stuart McRae Allan

01.12.2017 | Short report | Ausgabe 1/2017 Open Access

Teriflunomide and monomethylfumarate target HIV-induced neuroinflammation and neurotoxicity

Björn Ambrosius, Simon Faissner, Kirsten Guse, Marec von Lehe, Thomas Grunwald, Ralf Gold, Bastian Grewe, Andrew Chan

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microglia-derived IL-1β contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats

Qianpeng Han, Qiongyu Lin, Peixian Huang, Mengmeng Chen, Xin Hu, Hui Fu, Shaoru He, Fengcai Shen, Hongke Zeng, Yiyu Deng

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Macrophage and nerve interaction in endometriosis

Jinjie Wu, Hongyu Xie, Shuzhong Yao, Yanchun Liang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis

Marta Pulido-Salgado, Jose M. Vidal-Taboada, Gerardo Garcia Diaz-Barriga, Joan Serratosa, Tony Valente, Paola Castillo, Jonathan Matalonga, Marco Straccia, Josep M. Canals, Annabel Valledor, Carme Solà, Josep Saura

01.12.2017 | Research | Ausgabe 1/2017 Open Access

MicroRNA-142 regulates inflammation and T cell differentiation in an animal model of multiple sclerosis

Farideh Talebi, Samira Ghorbani, Wing Fuk Chan, Roobina Boghozian, Farimah Masoumi, Sedigheh Ghasemi, Mohammed Vojgani, Christopher Power, Farshid Noorbakhsh

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation

Katherine Conant, Stefano Daniele, P. Lorenzo Bozzelli, Tsion Abdi, Amanda Edwards, Arek Szklarczyk, India Olchefske, David Ottenheimer, Kathleen Maguire-Zeiss

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis

Shailender Singh, Tobias Dallenga, Anne Winkler, Shanu Roemer, Brigitte Maruschak, Heike Siebert, Wolfgang Brück, Christine Stadelmann

01.12.2017 | Short report | Ausgabe 1/2017 Open Access

Regulatory T cell frequency, but not plasma IL-33 levels, represents potential immunological biomarker to predict clinical response to intravenous immunoglobulin therapy

Mohan S. Maddur, Emmanuel Stephen-Victor, Mrinmoy Das, Praveen Prakhar, Varun K. Sharma, Vikas Singh, Magalie Rabin, Jamma Trinath, Kithiganahalli N. Balaji, Francis Bolgert, Jean-Michel Vallat, Laurent Magy, Srini V. Kaveri, Jagadeesh Bayry

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The Alzheimer’s disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway

Charlotte Jendresen, Vibeke Årskog, Michael R. Daws, Lars N. G. Nilsson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Analysis of monocyte infiltration in MPTP mice reveals that microglial CX3CR1 protects against neurotoxic over-induction of monocyte-attracting CCL2 by astrocytes

Vincent R. Parillaud, Guillaume Lornet, Yann Monnet, Anne-Laure Privat, Andrei T. Haddad, Vanessa Brochard, Amaury Bekaert, Camille Baudesson de Chanville, Etienne C. Hirsch, Christophe Combadière, Stéphane Hunot, Christian S. Lobsiger

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Development of a model of Saint Louis encephalitis infection and disease in mice

Rafael Elias Marques, Juliana L. Del Sarto, Rebeca P. F. Rocha, Giovanni F. Gomes, Allysson Cramer, Milene A. Rachid, Danielle G. Souza, Maurício L. Nogueira, Mauro M. Teixeira

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Lymphocytes have a role in protection, but not in pathogenesis, during La Crosse Virus infection in mice

Clayton W. Winkler, Lara M. Myers, Tyson A. Woods, Aaron B. Carmody, Katherine G. Taylor, Karin E. Peterson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Polysaccharides from Ganoderma lucidum attenuate microglia-mediated neuroinflammation and modulate microglial phagocytosis and behavioural response

Qing Cai, Yuanyuan Li, Gang Pei

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model

Simone Vodret, Giulia Bortolussi, Jana Jašprová, Libor Vitek, Andrés F. Muro

01.12.2017 | Research | Ausgabe 1/2017 Open Access

NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury

James P. Barrett, Rebecca J. Henry, Sonia Villapol, Bogdan A. Stoica, Alok Kumar, Mark P. Burns, Alan I. Faden, David J. Loane

01.12.2017 | Short report | Ausgabe 1/2017 Open Access

Activation of FXR pathway does not alter glial cell function

Stefanie Albrecht, Ann-Katrin Fleck, Ina Kirchberg, Stephanie Hucke, Marie Liebmann, Luisa Klotz, Tanja Kuhlmann

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo

Dan Li, Nan Liu, Hai-Hua Zhao, Xu Zhang, Hitoshi Kawano, Lu Liu, Liang Zhao, Hong-Peng Li

01.12.2017 | Short report | Ausgabe 1/2017 Open Access

Amelioration of experimental autoimmune encephalomyelitis by clozapine is not associated with defective CD4 T cell responses

Pirooz Zareie, Bronwen Connor, Anne Camille La Flamme

01.12.2017 | Research | Ausgabe 1/2017 Open Access

In vivo TSPO and cannabinoid receptor type 2 availability early in post-stroke neuroinflammation in rats: a positron emission tomography study

Teruyo Hosoya, Dai Fukumoto, Takeharu Kakiuchi, Shingo Nishiyama, Shigeyuki Yamamoto, Hiroyuki Ohba, Hideo Tsukada, Takatoshi Ueki, Kohji Sato, Yasuomi Ouchi

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat

Fan Liu, Zhiyao Wang, Yue Qiu, Min Wei, Chunyan Li, Yikuan Xie, Le Shen, Yuguang Huang, Chao Ma

01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Atypical periodic alternating nystagmus responding to high-dose intravenous immunoglobulins: a case report

Herminia Argente-Escrig, Luis Bataller, Claudio Krstulovic Roa, Vanesa Pérez Guillén, Herminio Perez Garrigues, Bonaventura Casanova Estruch

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Cerebrospinal fluid cell-free mitochondrial DNA is associated with HIV replication, iron transport, and mild HIV-associated neurocognitive impairment

Sanjay R. Mehta, Josué Pérez-Santiago, Todd Hulgan, Tyler R. C. Day, Jill Barnholtz-Sloan, Haley Gittleman, Scott Letendre, Ronald Ellis, Robert Heaton, Stephanie Patton, Jesse D. Suben, Donald Franklin, Debralee Rosario, David B. Clifford, Ann C. Collier, Christina M. Marra, Benjamin B. Gelman, Justin McArthur, Allen McCutchan, Susan Morgello, David Simpson, James Connor, Igor Grant, Asha Kallianpur

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Cytokine cascades induced by mechanical trauma injury alter voltage-gated sodium channel activity in intact cortical neurons

Weiqiang Chen, Jiangtao Sheng, Jingfang Guo, Guoyi Peng, Jinfang Hong, Bingbing Li, Xiaoxuan Chen, Kangsheng Li, Shousen Wang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression

Hai-Jiao Liu, Xiu-Xiu Pan, Bing-Qian Liu, Xuan Gui, Liang Hu, Chun-Yi Jiang, Yuan Han, Yi-Xin Fan, Yu-Lin Tang, Wen-Tao Liu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes

Zhengqiu Zhou, Adam D. Bachstetter, Claudia B. Späni, Saktimayee M. Roy, D. Martin Watterson, Linda J. Van Eldik

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microglia activation is essential for BMP7-mediated retinal reactive gliosis

Subramanian Dharmarajan, Debra L. Fisk, Christine M. Sorenson, Nader Sheibani, Teri L. Belecky-Adams

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

E. Soemirien Kasanmoentalib, Mercedes Valls Seron, Bart Ferwerda, Michael W. Tanck, Aeilko H. Zwinderman, Frank Baas, Arie van der Ende, William J. Schwaeble, Matthijs C. Brouwer, Diederik van de Beek

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Diffusion MRI quantifies early axonal loss in the presence of nerve swelling

Tsen-Hsuan Lin, Chia-Wen Chiang, Carlos J. Perez-Torres, Peng Sun, Michael Wallendorf, Robert E. Schmidt, Anne H. Cross, Sheng-Kwei Song

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The involvement of mast cells in the irinotecan-induced enteric neurons loss and reactive gliosis

Ludmila T. Nogueira, Deiziane V. S. Costa, Antoniella S. Gomes, Conceição S. Martins, Angeline M. H. P. Silva, Juliana M. Coelho-Aguiar, Patrícia Castelucci, Roberto C. P. Lima-Júnior, Renata F. C. Leitão, Vivaldo Moura-Neto, Gerly A. C. Brito

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring

Billy Vuong, Gary Odero, Stephanie Rozbacher, Mackenzie Stevenson, Stephanie M. Kereliuk, Troy J. Pereira, Vernon W. Dolinsky, Tiina M. Kauppinen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion

Yoshiki Hase, Lucinda Craggs, Mai Hase, William Stevenson, Janet Slade, Dianne Lopez, Rubin Mehta, Aiqing Chen, Di Liang, Arthur Oakley, Masafumi Ihara, Karen Horsburgh, Raj N. Kalaria

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The PD-1: PD-L1 pathway promotes development of brain-resident memory T cells following acute viral encephalitis

Sujata Prasad, Shuxian Hu, Wen S. Sheng, Priyanka Chauhan, Amar Singh, James R. Lokensgard

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Mu-opioid receptor and delta-opioid receptor differentially regulate microglial inflammatory response to control proopiomelanocortin neuronal apoptosis in the hypothalamus: effects of neonatal alcohol

Pallavi Shrivastava, Miguel A. Cabrera, Lucy G. Chastain, Nadka I. Boyadjieva, Shaima Jabbar, Tina Franklin, Dipak K. Sarkar

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo

Nicholas C. Woodward, Morgan C. Levine, Amin Haghani, Farimah Shirmohammadi, Arian Saffari, Constantinos Sioutas, Todd E. Morgan, Caleb E. Finch

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Adiponectin levels in the serum and cerebrospinal fluid of amyotrophic lateral sclerosis patients: possible influence on neuroinflammation?

Patrizia Bossolasco, Raffaella Cancello, Alberto Doretti, Claudia Morelli, Vincenzo Silani, Lidia Cova

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microglial depletion alters the brain neuroimmune response to acute binge ethanol withdrawal

T. Jordan Walter, Fulton T. Crews

01.12.2017 | Research | Ausgabe 1/2017 Open Access

TNF-α promotes extracellular vesicle release in mouse astrocytes through glutaminase

Kaizhe Wang, Ling Ye, Hongfang Lu, Huili Chen, Yanyan Zhang, Yunlong Huang, Jialin C. Zheng

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress

Simone Mori, Shuei Sugama, William Nguyen, Tatiana Michel, M. Germana Sanna, Manuel Sanchez-Alavez, Rigo Cintron-Colon, Gianluca Moroncini, Yoshihiko Kakinuma, Pamela Maher, Bruno Conti

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Early strong intrathecal inflammation in cerebellar type multiple system atrophy by cerebrospinal fluid cytokine/chemokine profiles: a case control study

Ryo Yamasaki, Hiroo Yamaguchi, Takuya Matsushita, Takayuki Fujii, Akio Hiwatashi, Jun-ichi Kira

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Exercise attenuates neurological deficits by stimulating a critical HSP70/NF-κB/IL-6/synapsin I axis in traumatic brain injury rats

Chung-Ching Chio, Hung-Jung Lin, Yu-Feng Tian, Yu-Chieh Chen, Mao-Tsun Lin, Cheng-Hsien Lin, Ching-Ping Chang, Chien-Chin Hsu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

Nathalia R. V. Dragano, Carina Solon, Albina F. Ramalho, Rodrigo F. de Moura, Daniela S. Razolli, Elisabeth Christiansen, Carlos Azevedo, Trond Ulven, Licio A. Velloso

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Fingolimod attenuates experimental autoimmune neuritis and contributes to Schwann cell-mediated axonal protection

Björn Ambrosius, Kalliopi Pitarokoili, Lisa Schrewe, Xiomara Pedreiturria, Jeremias Motte, Ralf Gold

01.12.2017 | Research | Ausgabe 1/2017 Open Access

GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma

Pete A. Williams, Catherine E. Braine, Nicole E. Foxworth, Kelly E. Cochran, Simon W. M. John

01.12.2017 | Research | Ausgabe 1/2017 Open Access

YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by β-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2

Zheng-Yi Li, Yoon Hee Chung, Eun-Joo Shin, Duy-Khanh Dang, Ji Hoon Jeong, Sung Kwon Ko, Seung-Yeol Nah, Tae Gon Baik, Jin Hyeong Jhoo, Wei-Yi Ong, Toshitaka Nabeshima, Hyoung-Chun Kim

01.12.2017 | Retraction Note | Ausgabe 1/2017 Open Access

Retraction Note to: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic rats

Jagadeesh Sridhara Rao, Hyung-Wook Kim, Matthew Kellom, Dede Greenstein, Mei Chen, Andrew David Kraft, Gaylia Jean Harry, Stanley Isaac Rapoport, Mireille Basselin

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Proteomic analysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response

Antwoine Flowers, Harris Bell-Temin, Ahmad Jalloh, Stanley M. Stevens Jr., Paula C. Bickford

01.12.2017 | Research | Ausgabe 1/2017 Open Access

HSYA alleviates secondary neuronal death through attenuating oxidative stress, inflammatory response, and neural apoptosis in SD rat spinal cord compression injury

Jun-peng Pei, Li-hong Fan, Kai Nan, Jia Li, Xiao-qian Dang, Kun-zheng Wang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Kososan, a Kampo medicine, prevents a social avoidance behavior and attenuates neuroinflammation in socially defeated mice

Naoki Ito, Eiji Hirose, Tatsuya Ishida, Atsushi Hori, Takayuki Nagai, Yoshinori Kobayashi, Hiroaki Kiyohara, Tetsuro Oikawa, Toshihiko Hanawa, Hiroshi Odaguchi

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity

Kelly S. Kirkley, Katriana A. Popichak, Maryam F. Afzali, Marie E. Legare, Ronald B. Tjalkens

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Sex-dependent treatment of chronic EAE with partial MHC class II constructs

Gil Benedek, Priya Chaudhary, Roberto Meza-Romero, Evan Calkins, Gail Kent, Halina Offner, Dennis Bourdette, Arthur A. Vandenbark

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Characteristics of primary rat microglia isolated from mixed cultures using two different methods

Li Lin, Rakhi Desai, Xiaoying Wang, Eng H. Lo, Changhong Xing

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors

Na Yue, Huijie Huang, Xiaocang Zhu, Qiuqin Han, Yalin Wang, Bing Li, Qiong Liu, Gencheng Wu, Yuqiu Zhang, Jin Yu

01.12.2017 | Short report | Ausgabe 1/2017 Open Access

A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis

Euan R. O. Allan, Rhiannon I. Campden, Benjamin W. Ewanchuk, Pankaj Tailor, Dale R. Balce, Neil T. McKenna, Catherine J. Greene, Amy L. Warren, Thomas Reinheckel, Robin M. Yates

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage

Qing Zhao, Xudong Che, Hongxia Zhang, Pianpian Fan, Guanping Tan, Liu Liu, Dengzhi Jiang, Jun Zhao, Xiang Xiang, Yidan Liang, Xiaochuan Sun, Zhaohui He

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation

Suzanne A. B. M. Aarts, Tom T. P. Seijkens, Pascal J. H. Kusters, Susanne M. A. van der Pol, Barbara Zarzycka, Priscilla D. A. M. Heijnen, Linda Beckers, Myrthe den Toom, Marion J. J. Gijbels, Louis Boon, Christian Weber, Helga E. de Vries, Gerry A. F. Nicolaes, Christine D. Dijkstra, Gijs Kooij, Esther Lutgens

01.12.2017 | Research | Ausgabe 1/2017 Open Access

LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface

Ø. Salvesen, M. R. Reiten, A. Espenes, M. K. Bakkebø, M. A. Tranulis, C. Ersdal

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice

Wenhui Qu, Andrea Johnson, Joo Hyun Kim, Abigail Lukowicz, Daniel Svedberg, Marija Cvetanovic

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy

Ellie Edlmann, Susan Giorgi-Coll, Peter C. Whitfield, Keri L. H. Carpenter, Peter J. Hutchinson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

MicroRNA-101a regulates microglial morphology and inflammation

Reiko Saika, Hiroshi Sakuma, Daisuke Noto, Shuhei Yamaguchi, Takashi Yamamura, Sachiko Miyake

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Receptor tyrosine kinases play a significant role in human oligodendrocyte inflammation and cell death associated with the Lyme disease bacterium Borrelia burgdorferi

Geetha Parthasarathy, Mario T. Philipp

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes

Stephanie S. Dusaban, Jerold Chun, Hugh Rosen, Nicole H. Purcell, Joan Heller Brown

01.12.2017 | Short Report | Ausgabe 1/2017 Open Access

B cells do not have a major pathophysiologic role in acute ischemic stroke in mice

Michael K. Schuhmann, Friederike Langhauser, Peter Kraft, Christoph Kleinschnitz

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Serum thyroid-stimulating hormone and interleukin-8 levels in boys with autism spectrum disorder

Sarika Singh, Umar Yazdani, Bharathi Gadad, Sayed Zaman, Linda S. Hynan, Nichole Roatch, Claire Schutte, C. Nathan Marti, Laura Hewitson, Dwight C. German

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effects of phosphodiesterase 3A modulation on murine cerebral microhemorrhages

Rachita K. Sumbria, Vitaly Vasilevko, Mher Mahoney Grigoryan, Annlia Paganini-Hill, Ronald Kim, David H. Cribbs, Mark J. Fisher

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune system

Nádia Pereira Gonçalves, João Moreira, Diana Martins, Paulo Vieira, Laura Obici, Giampaolo Merlini, Margarida Saraiva, Maria João Saraiva

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Acute neuroinflammation induces AIS structural plasticity in a NOX2-dependent manner

S. D. Benusa, N. M. George, B. A. Sword, G. H. DeVries, J. L. Dupree

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Regulatory T cells in multiple sclerosis and myasthenia gravis

K. M. Danikowski, S. Jayaraman, B. S. Prabhakar

01.12.2017 | Research | Ausgabe 1/2017 Open Access

YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer’s disease and other tauopathies

Marta Querol-Vilaseca, Martí Colom-Cadena, Jordi Pegueroles, Carla San Martín-Paniello, Jordi Clarimon, Olivia Belbin, Juan Fortea, Alberto Lleó

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway

Jun Zeng, Yizhao Chen, Rui Ding, Liang Feng, Zhenghao Fu, Shuo Yang, Xinqing Deng, Zhichong Xie, Shizhong Zheng

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement

Aarti Narang, Fei Qiao, Carl Atkinson, Hong Zhu, Xiaofeng Yang, Liudmila Kulik, V. Michael Holers, Stephen Tomlinson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130

Xinlei Wang, Eric B. Miller, Mayank Goswami, Pengfei Zhang, Kaitryn E. Ronning, Sarah J. Karlen, Robert J. Zawadzki, Edward N. Pugh Jr., Marie E. Burns

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Sac-1004, a vascular leakage blocker, reduces cerebral ischemia—reperfusion injury by suppressing blood–brain barrier disruption and inflammation

Haiying Zhang, Joon Ha Park, Sony Maharjan, Jeong Ae Park, Kyu-Sung Choi, Hyojin Park, Yoonjeong Jeong, Ji Hyeon Ahn, In Hye Kim, Jae-Chul Lee, Jeong Hwi Cho, In-Kyu Lee, Choong Hyun Lee, In Koo Hwang, Young-Myeong Kim, Young-Ger Suh, Moo-Ho Won, Young-Guen Kwon

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Identification of the flotillin-1/2 heterocomplex as a target of autoantibodies in bona fide multiple sclerosis

S. Hahn, G. Trendelenburg, M. Scharf, Y. Denno, S. Brakopp, B. Teegen, C. Probst, K. P. Wandinger, M. Buttmann, A. Haarmann, F. Szabados, M. vom Dahl, T. Kümpfel, P. Eichhorn, H. Gold, F. Paul, S. Jarius, N. Melzer, W. Stöcker, L. Komorowski

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Herpes simplex virus-1 infects the olfactory bulb shortly following ocular infection and exhibits a long-term inflammatory profile in the form of effector and HSV-1-specific T cells

Chandra M. Menendez, Daniel J. J. Carr

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Interleukin-1 receptor type 1 is overexpressed in neurons but not in glial cells within the rat superficial spinal dorsal horn in complete Freund adjuvant-induced inflammatory pain

Krisztina Holló, László Ducza, Zoltán Hegyi, Klaudia Dócs, Krisztina Hegedűs, Erzsébet Bakk, Ildikó Papp, Gréta Kis, Zoltán Mészár, Zsuzsanna Bardóczi, Miklós Antal

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The increased concentration of macrophage migration inhibitory factor in serum and cerebrospinal fluid of patients with tick-borne encephalitis

Sambor Grygorczuk, Miłosz Parczewski, Renata Świerzbińska, Piotr Czupryna, Anna Moniuszko, Justyna Dunaj, Maciej Kondrusik, Sławomir Pancewicz

01.12.2017 | Short Report | Ausgabe 1/2017 Open Access

Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination

Carsten Tue Berg, Reza Khorooshi, Nasrin Asgari, Trevor Owens

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation

Srikant Rangaraju, Syed Ali Raza, Andrea Pennati, Qiudong Deng, Eric B. Dammer, Duc Duong, Michael W. Pennington, Malu G. Tansey, James J. Lah, Ranjita Betarbet, Nicholas T. Seyfried, Allan I. Levey

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Evidence for an early innate immune response in the motor cortex of ALS

Javier H. Jara, Barış Genç, Macdonell J. Stanford, Peter Pytel, Raymond P. Roos, Sandra Weintraub, M. Marsel Mesulam, Eileen H. Bigio, Richard J. Miller, P. Hande Özdinler

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The Carbon monoxide releasing molecule ALF-186 mediates anti-inflammatory and neuroprotective effects via the soluble guanylate cyclase ß1 in rats’ retinal ganglion cells after ischemia and reperfusion injury

Felix Ulbrich, Claus Hagmann, Hartmut Buerkle, Carlos C. Romao, Nils Schallner, Ulrich Goebel, Julia Biermann

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Protease-activated receptor-1 activation by granzyme B causes neurotoxicity that is augmented by interleukin-1β

Paul R. Lee, Tory P. Johnson, Sharmilee Gnanapavan, Gavin Giovannoni, Tongguang Wang, Joseph P. Steiner, Marie Medynets, Mark J. Vaal, Valerie Gartner, Avindra Nath

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF-κB target gene expression in human microglia

Min Yin, Zhiying Chen, Yetong Ouyang, Huiyan Zhang, Zhigang Wan, Han Wang, Wei Wu, Xiaoping Yin

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Amplification and propagation of interleukin-1β signaling by murine brain endothelial and glial cells

Stephanie M. Krasnow, J. Gabriel Knoll, Santhosh Chakkaramakkil Verghese, Peter R. Levasseur, Daniel L. Marks

01.12.2017 | Research | Ausgabe 1/2017 Open Access

CXCL11 production in cerebrospinal fluid distinguishes herpes simplex meningitis from herpes simplex encephalitis

Liza Lind, Marie Studahl, Linn Persson Berg, Kristina Eriksson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The role of microglial P2X7: modulation of cell death and cytokine release

Yingbo He, Natalie Taylor, Lawrence Fourgeaud, Anindya Bhattacharya

01.12.2017 | Research | Ausgabe 1/2017 Open Access

MHC class II expression and potential antigen-presenting cells in the retina during experimental autoimmune uveitis

Deborah A. Lipski, Rémi Dewispelaere, Vincent Foucart, Laure E. Caspers, Matthieu Defrance, Catherine Bruyns, François Willermain

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats

Benjarat Changyaleket, Zhao Zhong Chong, Randal O. Dull, Danop Nanegrungsunk, Haoliang Xu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Activation of cannabinoid receptor type 2 attenuates surgery-induced cognitive impairment in mice through anti-inflammatory activity

Lingling Sun, Rui Dong, Xin Xu, Xi Yang, Mian Peng

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Chronic glucocorticoid exposure activates BK-NLRP1 signal involving in hippocampal neuron damage

Biqiong Zhang, Yaodong Zhang, Wenning Wu, Tanzhen Xu, Yanyan Yin, Junyan Zhang, Dake Huang, Weizu Li

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Ischaemic stroke and the recanalization drug tissue plasminogen activator interfere with antibacterial phagocyte function

Antje Vogelgesang, Claudia Lange, Lara Blümke, Georg Laage, Sarah Rümpel, Sönke Langner, Barbara M. Bröker, Alexander Dressel, Johanna Ruhnau

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

Colleen A. Mangold, Benjamin Wronowski, Mei Du, Dustin R. Masser, Niran Hadad, Georgina V. Bixler, Robert M. Brucklacher, Matthew M. Ford, William E. Sonntag, Willard M. Freeman

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease

Shinji Yamamoto, Kota Yamashina, Masaki Ishikawa, Mari Gotoh, Sosuke Yagishita, Kensuke Iwasa, Kei Maruyama, Kimiko Murakami-Murofushi, Keisuke Yoshikawa

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury

Xiangrong Chen, Shukai Wu, Chunnuan Chen, Baoyuan Xie, Zhongning Fang, Weipeng Hu, Junyan Chen, Huangde Fu, Hefan He

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Increased interleukin-27 cytokine expression in the central nervous system of multiple sclerosis patients

Patrice H. Lalive, Mario Kreutzfeldt, Odile Devergne, Imke Metz, Wolfgang Bruck, Doron Merkler, Caroline Pot

01.12.2017 | Research | Ausgabe 1/2017 Open Access

TLR4 response mediates ethanol-induced neurodevelopment alterations in a model of fetal alcohol spectrum disorders

María Pascual, Jorge Montesinos, Sandra Montagud-Romero, Jerónimo Forteza, Marta Rodríguez-Arias, José Miñarro, Consuelo Guerri

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: The role of PPAR activation during the systemic response to brain injury

Patrick Losey, Emma Ladds, Maud Laprais, Borna Guevel, Laura Burns, Regis Bordet, Daniel C. Anthony

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury

Raffaela Cipriani, Juan Carlos Chara, Alfredo Rodríguez-Antigüedad, Carlos Matute

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis

Kathrin Bail, Quirin Notz, Damiano M. Rovituso, Andrea Schampel, Marie Wunsch, Tobias Koeniger, Verena Schropp, Richa Bharti, Claus-Juergen Scholz, Konrad U. Foerstner, Christoph Kleinschnitz, Stefanie Kuerten

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Adaptive lymphocyte profiles correlate to brain Aβ burden in patients with mild cognitive impairment

Ann M. Stowe, Sara J. Ireland, Sterling B. Ortega, Ding Chen, Ryan M. Huebinger, Takashi Tarumi, Thomas S. Harris, C. Munro Cullum, Roger Rosenberg, Nancy L. Monson, Rong Zhang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Sensitization of ASIC3 by proteinase-activated receptor 2 signaling contributes to acidosis-induced nociception

Jing Wu, Ting-Ting Liu, Yi-Mei Zhou, Chun-Yu Qiu, Ping Ren, Ming Jiao, Wang-Ping Hu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

A translocator protein 18 kDa agonist protects against cerebral ischemia/reperfusion injury

Han-Dong Li, Minshu Li, Elaine Shi, Wei-Na Jin, Kristofer Wood, Rayna Gonzales, Qiang Liu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis

Leonie Stolz, Amin Derouiche, Kavi Devraj, Frank Weber, Robert Brunkhorst, Christian Foerch

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Choroid plexus-cerebrospinal fluid route for monocyte-derived macrophages after stroke

Ruimin Ge, Daniel Tornero, Masao Hirota, Emanuela Monni, Cecilia Laterza, Olle Lindvall, Zaal Kokaia

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation

Sylvia Torres-Odio, Jana Key, Hans-Hermann Hoepken, Júlia Canet-Pons, Lucie Valek, Bastian Roller, Michael Walter, Blas Morales-Gordo, David Meierhofer, Patrick N. Harter, Michel Mittelbronn, Irmgard Tegeder, Suzana Gispert, Georg Auburger

01.12.2017 | Research | Ausgabe 1/2017 Open Access

microRNA dysregulation in polyglutamine toxicity of TATA-box binding protein is mediated through STAT1 in mouse neuronal cells

Reema Roshan, Ashwani Choudhary, Aksheev Bhambri, Bhawani Bakshi, Tanay Ghosh, Beena Pillai

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental Streptococcus pneumoniae meningitis

Danfeng Xu, Di Lian, Jing Wu, Ying Liu, Mingjie Zhu, Jiaming Sun, Dake He, Ling Li

01.12.2017 | Erratum | Ausgabe 1/2017 Open Access

Erratum to: VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage

Catalina Abad, Bhavaani Jayaram, Laurine Becquet, Yuqi Wang, M. Sue O’Dorisio, James A. Waschek, Yossan-Var Tan

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Regulation of inflammation in Japanese encephalitis

Nils Lannes, Artur Summerfield, Luis Filgueira

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The chemokine fractalkine (CX3CL1) attenuates H2O2-induced demyelination in cerebellar slices

Sinead A. O’Sullivan, Kumlesh K. Dev

01.12.2017 | Letter to the Editor | Ausgabe 1/2017 Open Access

Bioinformatics analysis of glial inflammatory responses to air pollution

Chenyu Li, Wei Jiang, Nina Tang, Yan Xu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Age exacerbates microglial activation, oxidative stress, inflammatory and NOX2 gene expression, and delays functional recovery in a middle-aged rodent model of spinal cord injury

Ramona E. von Leden, Guzal Khayrullina, Kasey E. Moritz, Kimberly R. Byrnes

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inflammatory demyelination alters subcortical visual circuits

Sheila Espírito Santo Araújo, Henrique Rocha Mendonça, Natalie A. Wheeler, Paula Campello-Costa, Kimberle M. Jacobs, Flávia C. A. Gomes, Michael A. Fox, Babette Fuss

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Endogenous hydrogen sulphide attenuates NLRP3 inflammasome-mediated neuroinflammation by suppressing the P2X7 receptor after intracerebral haemorrhage in rats

Hengli Zhao, Pengyu Pan, Yang Yang, Hongfei Ge, Weixiang Chen, Jie Qu, Jiantao Shi, Gaoyu Cui, Xin Liu, Hua Feng, Yujie Chen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease

Lori N. Eidson, George T. Kannarkat, Christopher J. Barnum, Jianjun Chang, Jaegwon Chung, Chelsea Caspell-Garcia, Peggy Taylor, Brit Mollenhauer, Michael G. Schlossmacher, Larry Ereshefsky, Mark Yen, Catherine Kopil, Mark Frasier, Kenneth Marek, Vicki S. Hertzberg, Malú G. Tansey

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Retinopathy of prematurity: inflammation, choroidal degeneration, and novel promising therapeutic strategies

José Carlos Rivera, Mari Holm, Dordi Austeng, Tora Sund Morken, Tianwei (Ellen) Zhou, Alexandra Beaudry-Richard, Estefania Marin Sierra, Olaf Dammann, Sylvain Chemtob

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Responses of rat and mouse primary microglia to pro- and anti-inflammatory stimuli: molecular profiles, K+ channels and migration

Doris Lam, Starlee Lively, Lyanne C. Schlichter

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Anti-inflammatory and immunomodulatory mechanisms of atorvastatin in a murine model of traumatic brain injury

Xin Xu, Weiwei Gao, Shiqi Cheng, Dongpei Yin, Fei Li, Yingang Wu, Dongdong Sun, Shuai Zhou, Dong Wang, Yongqiang Zhang, Rongcai Jiang, Jianning Zhang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Prophylactic inhibition of neutrophil elastase prevents the development of chronic neuropathic pain in osteoarthritic mice

Milind M. Muley, Eugene Krustev, Allison R. Reid, Jason J. McDougall

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Neuroinflammation contributes to autophagy flux blockage in the neurons of rostral ventrolateral medulla in stress-induced hypertension rats

Dongshu Du, Li Hu, Jiaxiang Wu, Qin Wu, Wenjing Cheng, Yuhong Guo, Ruijuan Guan, Yahui Wang, Xingxin Chen, Xanxia Yan, Danian Zhu, Jijiang Wang, Shutian Zhang, Yanfang Guo, Chunmei Xia

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Docosahexaenoic acid-containing choline phospholipid modulates LPS-induced neuroinflammation in vivo and in microglia in vitro

Célia Fourrier, Julie Remus-Borel, Andrew D. Greenhalgh, Michel Guichardant, Nathalie Bernoud-Hubac, Michel Lagarde, Corinne Joffre, Sophie Layé

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Pattern II and pattern III MS are entities distinct from pattern I MS: evidence from cerebrospinal fluid analysis

S. Jarius, F.B. König, I. Metz, K. Ruprecht, F. Paul, W. Brück, B. Wildemann

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Safety and in vivo immune assessment of escalating doses of oral laquinimod in patients with RRMS

Tjalf Ziemssen, Hayrettin Tumani, Tony Sehr, Katja Thomas, Friedemann Paul, Nils Richter, Emil Samara, Ofer Spiegelstein, Ella Sorani, Oren Bar-Ilan, Dorit Mimrod, Liat Hayardeny

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Cerebrospinal fluid CXCL13 as a diagnostic marker of neuroborreliosis in children: a retrospective case-control study

M. M. Remy, N. Schöbi, L. Kottanattu, S. Pfister, A. Duppenthaler, F. Suter-Riniker

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Selective suppression of the JNK-MMP2/9 signal pathway by tetramethylpyrazine attenuates neuropathic pain in rats

Lai Jiang, Cai-Long Pan, Chao-Yu Wang, Bing-Qian Liu, Yuan Han, Liang Hu, Lei Liu, Yang Yang, Jun-Wei Qu, Wen-Tao Liu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Brain ureido degenerative protein modifications are associated with neuroinflammation and proteinopathy in Alzheimer’s disease with cerebrovascular disease

Xavier Gallart-Palau, Aida Serra, Benjamin Sian Teck Lee, Xue Guo, Siu Kwan Sze

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Arginine vasopressin altered the expression of monocarboxylate transporters in cultured astrocytes isolated from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats

Kazuo Yamagata, Natsumi Takahashi, Nozomi Akita, Toru Nabika

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis

Volodymyr Gerzanich, Tapas K. Makar, Poornachander Reddy Guda, Min Seong Kwon, Jesse A. Stokum, Seung Kyoon Woo, Svetlana Ivanova, Alexander Ivanov, Rupal I. Mehta, Alexandra Brooke Morris, Joseph Bryan, Christopher T. Bever, J. Marc Simard

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype

Milena Fioravante, Bruna Bombassaro, Albina F. Ramalho, Nathalia R. Dragano, Joseane Morari, Carina Solon, Natalia Tobar, Celso D. Ramos, Licio A. Velloso

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers - pre-clinical and clinical investigations

Joana Prata, Susana G. Santos, Maria Inês Almeida, Rui Coelho, Mário A. Barbosa

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Functional changes in hippocampal synaptic signaling in offspring survivors of a mouse model of intrauterine inflammation

Melissa H. Kelley, Wendy W. Wu, Jun Lei, Michael McLane, Han Xie, Kyle D. Hart, Leonardo Pereira, Irina Burd, James Maylie

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina

José Carlos Rivera, Baraa Noueihed, Ankush Madaan, Isabelle Lahaie, Jingyi Pan, Jaques Belik, Sylvain Chemtob

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Priming astrocytes with TNF enhances their susceptibility to Trypanosoma cruzi infection and creates a self-sustaining inflammatory milieu

Andrea Alice Silva, Rafael Rodrigues Silva, Daniel Gibaldi, Rafael Meyer Mariante, Jessica Brandão dos Santos, Isabela Resende Pereira, Otacílio Cruz Moreira, Joseli Lannes-Vieira

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Peroxisome proliferator-activated receptor-gamma: potential molecular therapeutic target for HIV-1-associated brain inflammation

Amila Omeragic, Md Tozammel Hoque, U-yeong Choi, Reina Bendayan

01.12.2017 | Short Report | Ausgabe 1/2017 Open Access

Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation

Anna Hammer, Anne Schliep, Stefanie Jörg, Aiden Haghikia, Ralf Gold, Markus Kleinewietfeld, Dominik N. Müller, Ralf A. Linker

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats

Juan Niu, Dujuan Huang, Rui Zhou, MingXia Yue, Tao Xu, Junna Yang, Li He, Hong Tian, XiaoHong Liu, Junwei Zeng

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Fluoxetine-enhanced autophagy ameliorates early brain injury via inhibition of NLRP3 inflammasome activation following subarachnoid hemorrhage in rats

Jian-ru Li, Hang-zhe Xu, Sheng Nie, Yu-cong Peng, Lin-Feng Fan, Zhi-jiang Wang, Cheng Wu, Feng Yan, Jing-yin Chen, Chi Gu, Chun Wang, Jing-sen Chen, Lin Wang, Gao Chen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke

Shuang Chen, Zhiping Dong, Man Cheng, Yaqian Zhao, Mengying Wang, Na Sai, Xuan Wang, Huan Liu, Guowei Huang, Xumei Zhang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Using blood cytokine measures to define high inflammatory biotype of schizophrenia and schizoaffective disorder

Danny Boerrigter, Thomas W. Weickert, Rhoshel Lenroot, Maryanne O’Donnell, Cherrie Galletly, Dennis Liu, Martin Burgess, Roxanne Cadiz, Isabella Jacomb, Vibeke S. Catts, Stu G. Fillman, Cynthia Shannon Weickert

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Primary cilia modulate TLR4-mediated inflammatory responses in hippocampal neurons

Hyunjung Baek, Hyo Jung Shin, Jwa-Jin Kim, Nara Shin, Sena Kim, Min-Hee Yi, Enji Zhang, Jinpyo Hong, Joon Won Kang, Yonghyun Kim, Cuk-Seong Kim, Dong Woon Kim

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice

Mengmeng Li, Chenli Li, Hanjie Yu, Xiongxiong Cai, Xinbei Shen, Xin Sun, Jinting Wang, Yanhua Zhang, Chuang Wang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Increased frequency of IL-6-producing non-classical monocytes in neuromyelitis optica spectrum disorder

Byung Soo Kong, Yeseul Kim, Ga Young Kim, Jae-Won Hyun, Su-Hyun Kim, Aeran Jeong, Ho Jin Kim

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Anti-inflammatory effects of astroglial α7 nicotinic acetylcholine receptors are mediated by inhibition of the NF-κB pathway and activation of the Nrf2 pathway

Hiral Patel, Jessica McIntire, Sarah Ryan, Anthone Dunah, Ralph Loring

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer’s disease, and neuronal injury in humans: a cohort study

Andreas Pikwer, Markus Castegren, Sijal Namdar, Kaj Blennow, Henrik Zetterberg, Niklas Mattsson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

αVβ3 Integrin regulates astrocyte reactivity

Raúl Lagos-Cabré, Alvaro Alvarez, Milene Kong, Francesca Burgos-Bravo, Areli Cárdenas, Edgardo Rojas-Mancilla, Ramón Pérez-Nuñez, Rodrigo Herrera-Molina, Fabiola Rojas, Pascal Schneider, Mario Herrera-Marschitz, Andrew F. G. Quest, Brigitte van Zundert, Lisette Leyton

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Acute maternal oxidant exposure causes susceptibility of the fetal brain to inflammation and oxidative stress

Feroz Akhtar, Christopher A. Rouse, Gabriel Catano, Marcus Montalvo, Sarah L. Ullevig, Reto Asmis, Kusum Kharbanda, Shivani K. Maffi

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The contribution of the acute phase response to the pathogenesis of relapse in chronic-relapsing experimental autoimmune encephalitis models of multiple sclerosis

Silvy Mardiguian, Emma Ladds, Roberta Turner, Hazel Shepherd, Sandra J. Campbell, Daniel C. Anthony

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats

Hidetsugu Maekawa, Yoshiteru Tada, Kenji Yagi, Takeshi Miyamoto, Keiko T. Kitazato, Masaaki Korai, Junichiro Satomi, Tomoki Hashimoto, Shinji Nagahiro

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Agonists for G-protein-coupled receptor 84 (GPR84) alter cellular morphology and motility but do not induce pro-inflammatory responses in microglia

Li Wei, Kyohei Tokizane, Hiroyuki Konishi, Hua-Rong Yu, Hiroshi Kiyama

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Role of microglial amylin receptors in mediating beta amyloid (Aβ)-induced inflammation

Wen Fu, Vlatka Vukojevic, Aarti Patel, Rania Soudy, David MacTavish, David Westaway, Kamaljit Kaur, Valeri Goncharuk, Jack Jhamandas

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Analysis of plasma multiplex cytokines and increased level of IL-10 and IL-1Ra cytokines in febrile seizures

Kyungmin Kim, Byung Ok Kwak, Aram Kwon, Jongseok Ha, Soo-Jin Kim, Sun Whan Bae, Jae Sung Son, Soo-Nyung Kim, Ran Lee

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Withania somnifera as a potential candidate to ameliorate high fat diet-induced anxiety and neuroinflammation

Taranjeet Kaur, Gurcharan Kaur

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Erythropoietin reduces experimental autoimmune encephalomyelitis severity via neuroprotective mechanisms

M. Moransard, M. Bednar, K. Frei, M. Gassmann, O. O. Ogunshola

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The potassium channel KCa3.1 constitutes a pharmacological target for astrogliosis associated with ischemia stroke

Mengni Yi, Tianjiao Wei, Yanxia Wang, Qin Lu, Gaoxian Chen, Xiaoling Gao, Herbert M. Geller, Hongzhuan Chen, Zhihua Yu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

Chittappen K. Prajeeth, Julius Kronisch, Reza Khorooshi, Benjamin Knier, Henrik Toft-Hansen, Viktoria Gudi, Stefan Floess, Jochen Huehn, Trevor Owens, Thomas Korn, Martin Stangel

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Elevated microRNA-129-5p level ameliorates neuroinflammation and blood-spinal cord barrier damage after ischemia-reperfusion by inhibiting HMGB1 and the TLR3-cytokine pathway

Xiao-Qian Li, Feng-Shou Chen, Wen-Fei Tan, Bo Fang, Zai-Li Zhang, Hong Ma

01.12.2017 | Correction | Ausgabe 1/2017 Open Access

Correction to: the disruption of mitochondrial axonal transport is an early event in neuroinflammation

Oihana Errea, Beatriz Moreno, Alba Gonzalez-Franquesa, Pablo M. Garcia-Roves, Pablo Villoslada

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice

Wu Jiang, Maoqiang Li, Fan He, Shaobo Zhou, Liulong Zhu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination

Patrick Peschl, Kathrin Schanda, Bleranda Zeka, Katherine Given, Denise Böhm, Klemens Ruprecht, Albert Saiz, Andreas Lutterotti, Kevin Rostásy, Romana Höftberger, Thomas Berger, Wendy Macklin, Hans Lassmann, Monika Bradl, Jeffrey L. Bennett, Markus Reindl

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain

Pierre J. Doyen, Maxime Vergouts, Amandine Pochet, Nathalie Desmet, Sabien van Neerven, Gary Brook, Emmanuel Hermans

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance

Wen-Jun Su, Wei Peng, Hong Gong, Yun-Zi Liu, Yi Zhang, Yong-Jie Lian, Zhi-Yong Cao, Ran Wu, Lin-Lin Liu, Bo Wang, Yun-Xia Wang, Chun-Lei Jiang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Lidocaine alleviates morphine tolerance via AMPK-SOCS3-dependent neuroinflammation suppression in the spinal cord

Yan Zhang, Gao-Jian Tao, Liang Hu, Jie Qu, Yuan Han, Guangqin Zhang, Yanning Qian, Chun-Yi Jiang, Wen-Tao Liu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala

Elaine O’Loughlin, Janelle M. P. Pakan, Deniz Yilmazer-Hanke, Kieran W. McDermott

01.12.2017 | Research | Ausgabe 1/2017 Open Access

The analgesic effects of triptolide in the bone cancer pain rats via inhibiting the upregulation of HDACs in spinal glial cells

Xiao-Fan Hu, Xiao-Tao He, Kai-Xiang Zhou, Chen Zhang, Wen-Jun Zhao, Ting Zhang, Jin-Lian Li, Jian-Ping Deng, Yu-Lin Dong

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inhibition of DAMP signaling as an effective adjunctive treatment strategy in pneumococcal meningitis

Ilias Masouris, Matthias Klein, Susanne Dyckhoff, Barbara Angele, H. W. Pfister, Uwe Koedel

01.12.2017 | Research | Ausgabe 1/2017 Open Access

DHCR24 exerts neuroprotection upon inflammation-induced neuronal death

Henna Martiskainen, Kaisa M. A. Paldanius, Teemu Natunen, Mari Takalo, Mikael Marttinen, Stina Leskelä, Nadine Huber, Petra Mäkinen, Enni Bertling, Hiramani Dhungana, Mikko Huuskonen, Paavo Honkakoski, Pirta Hotulainen, Kirsi Rilla, Jari Koistinaho, Hilkka Soininen, Tarja Malm, Annakaisa Haapasalo, Mikko Hiltunen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Chronic cerebral hypoperfusion induces post-stroke dementia following acute ischemic stroke in rats

Dong Bin Back, Kyoung Ja Kwon, Dong-Hee Choi, Chan Young Shin, Jongmin Lee, Seol-Heui Han, Hahn Young Kim

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Endothelial α6β4 integrin protects during experimental autoimmune encephalomyelitis-induced neuroinflammation by maintaining vascular integrity and tight junction protein expression

Jennifer V. Welser, Sebok K. Halder, Ravi Kant, Amin Boroujerdi, Richard Milner

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Microglial dynamics after axotomy-induced retinal ganglion cell death

Francisco M. Nadal-Nicolás, Manuel Jiménez-López, Manuel Salinas-Navarro, Paloma Sobrado-Calvo, Manuel Vidal-Sanz, Marta Agudo-Barriuso

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Interleukin-1β signaling in fenestrated capillaries is sufficient to trigger sickness responses in mice

J. Gabriel Knoll, Stephanie M. Krasnow, Daniel L. Marks

01.12.2017 | Research | Ausgabe 1/2017 Open Access

EZH2 suppression in glioblastoma shifts microglia toward M1 phenotype in tumor microenvironment

Yatao Yin, Shuwei Qiu, Xiangpen Li, Bo Huang, Yun Xu, Ying Peng

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Hypertonic saline for prevention of delirium in geriatric patients who underwent hip surgery

Xi Xin, Fei Xin, Xuguang Chen, Qi Zhang, Yanan Li, Shuping Huo, Chongfu Chang, Qiujun Wang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation

Meetu Wadhwa, Amit Prabhakar, Koushik Ray, Koustav Roy, Punita Kumari, Prabhash Kumar Jha, Krishna Kishore, Sanjeev Kumar, Usha Panjwani

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Peripheral immune tolerance alleviates the intracranial lipopolysaccharide injection-induced neuroinflammation and protects the dopaminergic neurons from neuroinflammation-related neurotoxicity

Yang Liu, Xin Xie, Li-Ping Xia, Hong Lv, Fan Lou, Yan Ren, Zhi-Yi He, Xiao-Guang Luo

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Anti-NF155 chronic inflammatory demyelinating polyradiculoneuropathy strongly associates to HLA-DRB15

Laura Martinez-Martinez, Ma. Cinta Lleixà, Gemma Boera-Carnicero, Andrea Cortese, Jérôme Devaux, Ana Siles, Yusuf Rajabally, Alicia Martinez-Piñeiro, Alejandra Carvajal, Julio Pardo, Emilien Delmont, Shahram Attarian, Jordi Diaz-Manera, Ilaria Callegari, Enrico Marchioni, Diego Franciotta, Luana Benedetti, Guiseppe Lauria, Oscar de la Calle Martin, Cándido Juárez, Isabel Illa, Luis Querol

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Selective depletion of microglial progranulin in mice is not sufficient to cause neuronal ceroid lipofuscinosis or neuroinflammation

Terri L. Petkau, Natalia Kosior, Kathleen de Asis, Colúm Connolly, Blair R. Leavitt

01.12.2017 | Correction | Ausgabe 1/2017 Open Access

Correction to: Analysis of plasma multiplex cytokines and increased level of IL-10 and IL-1Ra cytokines in febrile seizures

Kyungmin Kim, Byung Ok Kwak, Aram Kwon, Jongseok Ha, Soo-Jin Kim, Sun Whan Bae, Jae Sung Son, Soo-Nyung Kim, Ran Lee

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Humoral response in experimental autoimmune encephalomyelitis targets neural precursor cells in the central nervous system of naive rodents

Evangelia Kesidou, Olga Touloumi, Roza Lagoudaki, Evangelia Nousiopoulou, Paschalis Theotokis, Kyriaki-Nepheli Poulatsidou, Marina Boziki, Evangelia Kofidou, Nickoleta Delivanoglou, Fani Minti, Georgios Hadjigeorgiou, Nikolaos Grigoriadis, Constantina Simeonidou

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Blocking ATP-sensitive potassium channel alleviates morphine tolerance by inhibiting HSP70-TLR4-NLRP3-mediated neuroinflammation

Jie Qu, Xue-You Tao, Peng Teng, Yan Zhang, Ci-Liang Guo, Liang Hu, Yan-Ning Qian, Chun-Yi Jiang, Wen-Tao Liu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

MicroRNA expression changes in association with changes in interleukin-1ß/interleukin10 ratios produced by monocytes in autism spectrum disorders: their association with neuropsychiatric symptoms and comorbid conditions (observational study)

Harumi Jyonouchi, Lee Geng, Deanna L. Streck, James J. Dermody, Gokce A. Toruner

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage

Chun-Hu Wu, Song-Kun Shyue, Tai-Ho Hung, Shin Wen, Chao-Chang Lin, Che-Feng Chang, Szu-Fu Chen

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-κB signaling in an IL-6-dependent manner

Lin Sun, Man Li, Xun Ma, Haoyu Feng, Junlai Song, Cong Lv, Yajun He

01.12.2017 | Review | Ausgabe 1/2017 Open Access

Novel pathomechanisms in inflammatory neuropathies

David Schafflick, Bernd C. Kieseier, Heinz Wiendl, Gerd Meyer zu Horste

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Mild endoplasmic reticulum stress ameliorates lipopolysaccharide-induced neuroinflammation and cognitive impairment via regulation of microglial polarization

Yi-wei Wang, Qin Zhou, Xiang Zhang, Qing-qing Qian, Jia-wen Xu, Peng-fei Ni, Yan-ning Qian

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress

Dan Zhao, Xulin Xu, Linna Pan, Wei Zhu, Xiaopei Fu, Lianjun Guo, Qing Lu, Jian Wang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Regulator of oligodendrocyte maturation, miR-219, a potential biomarker for MS

Ilona B. Bruinsma, Marie van Dijk, Claire Bridel, Timothy van de Lisdonk, Sanne Q. Haverkort, Tessel F. Runia, Lawrence Steinman, Rogier Q. Hintzen, Joep Killestein, Marcel M. Verbeek, Charlotte E. Teunissen, Brigit A. de Jong

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Selective proliferative response of microglia to alternative polarization signals

Giovanna Pepe, Marcella De Maglie, Lucia Minoli, Alessandro Villa, Adriana Maggi, Elisabetta Vegeto

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation

Hiramani Dhungana, Mikko T. Huuskonen, Merja Jaronen, Sighild Lemarchant, Humair Ali, Velta Keksa-Goldsteine, Gundars Goldsteins, Katja M. Kanninen, Jari Koistinaho, Tarja Malm

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Neuronal CCL2 expression drives inflammatory monocyte infiltration into the brain during acute virus infection

Charles L. Howe, Reghann G. LaFrance-Corey, Emma N. Goddery, Renee K. Johnson, Kanish Mirchia

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome

Pei Jiang, Yujin Guo, Ruili Dang, Mengqi Yang, Dehua Liao, Huande Li, Zhen Sun, Qingyan Feng, Pengfei Xu

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway

Ji-Hyun Park, Young Ho Seo, Jung-Hee Jang, Chul-Ho Jeong, Sooyeun Lee, Byoungduck Park

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes

Gabriel Gustafsson, Veronica Lindström, Jinar Rostami, Eva Nordström, Lars Lannfelt, Joakim Bergström, Martin Ingelsson, Anna Erlandsson

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Contrasting effect of the latency-reversing agents bryostatin-1 and JQ1 on astrocyte-mediated neuroinflammation and brain neutrophil invasion

Alizé Proust, Corinne Barat, Mathieu Leboeuf, Jean Drouin, Michel J. Tremblay

01.12.2017 | Research | Ausgabe 1/2017 Open Access

DNA repair protein APE1 is involved in host response during pneumococcal meningitis and its expression can be modulated by vitamin B6

Leonam G. Coutinho, Ana Helena Sales de Oliveira, Matthias Witwer, Stephen L. Leib, Lucymara F. Agnez-Lima

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Distinct cytokine patterns may regulate the severity of neonatal asphyxia—an observational study

Anna Bajnok, László Berta, Csaba Orbán, Gábor Veres, Dénes Zádori, Hajnalka Barta, Ünőke Méder, László Vécsei, Tivadar Tulassay, Miklós Szabó, Gergely Toldi

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Human microglia and astrocytes constitutively express the neurokinin-1 receptor and functionally respond to substance P

Amanda R. Burmeister, M. Brittany Johnson, Vinita S. Chauhan, Megan J. Moerdyk-Schauwecker, Ada D. Young, Ian D. Cooley, Alejandra N. Martinez, Geeta Ramesh, Mario T. Philipp, Ian Marriott

01.12.2017 | Research | Ausgabe 1/2017 Open Access

AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity

Soraya Wilke Saliba, Ariel R. Marcotegui, Ellen Fortwängler, Johannes Ditrich, Juan Carlos Perazzo, Eduardo Muñoz, Antônio Carlos Pinheiro de Oliveira, Bernd L. Fiebich

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Dimethylarginines in patients with intracerebral hemorrhage: association with outcome, hematoma enlargement, and edema

Hans Worthmann, Na Li, Jens Martens-Lobenhoffer, Meike Dirks, Ramona Schuppner, Ralf Lichtinghagen, Jan T. Kielstein, Peter Raab, Heinrich Lanfermann, Stefanie M. Bode-Böger, Karin Weissenborn

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Infiltration and persistence of lymphocytes during late-stage cerebral ischemia in middle cerebral artery occlusion and photothrombotic stroke models

Yan Feng, Shiwei Liao, Changjuan Wei, Dongmei Jia, Kristofer Wood, Qiang Liu, Xiaoying Wang, Fu-Dong Shi, Wei-Na Jin

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Macrophages in trigeminal ganglion contribute to ectopic mechanical hypersensitivity following inferior alveolar nerve injury in rats

Dulguun Batbold, Masamichi Shinoda, Kuniya Honda, Akihiko Furukawa, Momoko Koizumi, Ryuta Akasaka, Satoshi Yamaguchi, Koichi Iwata

01.12.2017 | Research | Ausgabe 1/2017 Open Access

EBI2 receptor regulates myelin development and inhibits LPC-induced demyelination

Aleksandra Rutkowska, Andreas W. Sailer, Kumlesh K. Dev

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia

Pooja-Shree Mishra, K. Vijayalakshmi, A. Nalini, T. N. Sathyaprabha, B. W. Kramer, Phalguni Anand Alladi, T. R. Raju

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome

Elizabeth Nance, Siva P. Kambhampati, Elizabeth S. Smith, Zhi Zhang, Fan Zhang, Sarabdeep Singh, Michael V. Johnston, Rangaramanujam M. Kannan, Mary E. Blue, Sujatha Kannan

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype

I. Plastira, E. Bernhart, M. Goeritzer, T. DeVaney, H. Reicher, A. Hammer, B. Lohberger, A. Wintersperger, B. Zucol, W. F. Graier, D. Kratky, E. Malle, W. Sattler

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Prenatal alcohol exposure is a risk factor for adult neuropathic pain via aberrant neuroimmune function

Joshua J. Sanchez, Shahani Noor, Suzy Davies, Daniel Savage, Erin D. Milligan

01.12.2017 | Research | Ausgabe 1/2017 Open Access

γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in mice

Xiaoli Zhang, Eridan Rocha-Ferreira, Tao Li, Regina Vontell, Darakhshan Jabin, Sha Hua, Kai Zhou, Arshed Nazmi, Anna-Maj Albertsson, Kristina Sobotka, Joakim Ek, Claire Thornton, Henrik Hagberg, Carina Mallard, Jianmei W. Leavenworth, Changlian Zhu, Xiaoyang Wang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Tenuigenin protects dopaminergic neurons from inflammation via suppressing NLRP3 inflammasome activation in microglia

Zheng Fan, Zhigang Liang, Hui Yang, Yuting Pan, Yan Zheng, Xiaomin Wang

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Monocyte-derived tissue transglutaminase in multiple sclerosis patients: reflecting an anti-inflammatory status and function of the cells?

Claudia Sestito, John J. P. Brevé, Marja C. J. A. van Eggermond, Joep Killestein, Charlotte E. Teunissen, Joram van Rossum, Micha M. M. Wilhelmus, Benjamin Drukarch, Peter J. van den Elsen, Anne-Marie van Dam

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Donepezil suppresses intracellular Ca2+ mobilization through the PI3K pathway in rodent microglia

Yoshinori Haraguchi, Yoshito Mizoguchi, Masahiro Ohgidani, Yoshiomi Imamura, Toru Murakawa-Hirachi, Hiromi Nabeta, Hiroshi Tateishi, Takahiro A. Kato, Akira Monji

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis

Wissam Beaino, Bieneke Janssen, Gijs Kooij, Susanne M. A. van der Pol, B. van Het Hof, Jack van Horssen, Albert D. Windhorst, Helga E. de Vries

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures

Nathaly Espitia Pinzón, John J. P. Brevé, John G. J. M. Bol, Benjamin Drukarch, Wia Baron, Anne-Marie van Dam

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Inflammatory dysregulation of monocytes in pediatric patients with obsessive-compulsive disorder

Natalia Rodríguez, Astrid Morer, E. Azucena González-Navarro, Carles Serra-Pages, Daniel Boloc, Teresa Torres, Susana García-Cerro, Sergi Mas, Patricia Gassó, Luisa Lázaro

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Reciprocal interactions between prostaglandin E2- and estradiol-dependent signaling pathways in the injured zebra finch brain

Alyssa L. Pedersen, Colin J. Saldanha

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  • 2016 | Buch

    Komplikationen in der Neurologie

    Das Buch schildert Ereignisse im Rahmen der Neuromedizin, die während der Diagnostik und Therapie neurologischer Erkrankungen und Symptome auftreten können. Die Fallbeispiele sensibilisieren Sie für mögliche Risikofaktoren, um das Auftreten solcher Komplikationen zu vermeiden.

    Herausgeber:
    Frank Block
  • 2017 | Buch

    Facharztwissen Psychiatrie, Psychosomatik und Psychotherapie

    Leitsymptome, Untersuchungsmethoden, Krankheitsbilder, Notfälle & Co. – mit der Neuauflage des "Facharztwissens" sind Sie auf die Facharztprüfung in Psychiatrie und Psychotherapie optimal vorbereitet. In dieser 2. Auflage sind die Kapitel zu psychosomatischen Störungen deutlich ausgebaut.

    Herausgeber:
    Prof. Dr. Dr. Frank Schneider
  • 2019 | Buch

    Kompendium der Psychotherapie

    Für Ärzte und Psychologen

    Dieses Werk wendet sich an Ärzte und Psychologen, die an psychiatrischen und psychosomatischen Kliniken oder an Psychotherapeutischen Ausbildungsinstituten arbeiten und in den vorhandenen Lehrbüchern der Psychotherapie den Brückenschlag zur …

    Herausgeber:
    Tilo Kircher
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