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Malaria Journal

Ausgabe 1/2014

Inhalt (512 Artikel)

Open Access Commentary

Strategic roles for behaviour change communication in a changing malaria landscape

Hannah Koenker, Joseph Keating, Martin Alilio, Angela Acosta, Matthew Lynch, Fatoumata Nafo-Traore

Open Access Research

Reduced ADAMTS13 activity is associated with an ADAMTS13 SNP, fever and microparticles in a malaria-like model

Sirima Kraisin, Attakorn Palasuwan, Supaluk Popruk, Duangdao Nantakomol

Open Access Research

Population structure and spatio-temporal transmission dynamics of Plasmodium vivax after radical cure treatment in a rural village of the Peruvian Amazon

Christopher Delgado-Ratto, Veronica E Soto-Calle, Peter Van den Eede, Dionicia Gamboa, Angel Rosas, Emmanuel N Abatih, Hugo Rodriguez Ferrucci, Alejandro Llanos-Cuentas, Jean-Pierre Van Geertruyden, Annette Erhart, Umberto D’Alessandro

Open Access Research

Estimating malaria parasite density among pregnant women at central Sudan using actual and assumed white blood cell count

AbdElrahium D Haggaz, Leana M Elbashir, Gamal K Adam, Duria A Rayis, Ishag Adam

Open Access Research

Adherence to artemisinin-based combination therapy for the treatment of malaria: a systematic review of the evidence

Kristin Banek, Mirza Lalani, Sarah G Staedke, Daniel Chandramohan

Open Access Research

Spatial trend, environmental and socioeconomic factors associated with malaria prevalence in Chennai

Divya Subash Kumar, Ramachandran Andimuthu, Rupa Rajan, Mada Suresh Venkatesan

Open Access Methodology

Simple, sensitive and quantitative bioluminescence assay for determination of malaria pre-patent period

Vanessa Zuzarte-Luis, Joana Sales-Dias, Maria M Mota

Open Access Research

Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds

Sean R Marcsisin, Jason C Sousa, Gregory A Reichard, Diana Caridha, Qiang Zeng, Norma Roncal, Ronan McNulty, Julio Careagabarja, Richard J Sciotti, Jason W Bennett, Victor E Zottig, Gregory Deye, Qigui Li, Lisa Read, Mark Hickman, N P Dhammika Nanayakkara, Larry A Walker, Bryan Smith, Victor Melendez, Brandon S Pybus

Open Access Research

Assessing the optimal virulence of malaria‐targeting mosquito pathogens: a mathematical study of engineered Metarhizium anisopliae

Bernhard P Konrad, Michael Lindstrom, Anja Gumpinger, Jielin Zhu, Daniel Coombs

Open Access Research

Genetic diversity of Plasmodium vivax population in Anhui province of China

Bo Huang, Shiguang Huang, Xin-zhuan Su, Hong Guo, Yucheng Xu, Fei Xu, Xuchu Hu, Yaming Yang, Shanqing Wang, Fangli Lu

Open Access Research

Differential effects of inbreeding and selection on male reproductive phenotype associated with the colonization and laboratory maintenance of Anopheles gambiae

Rowida Baeshen, Nkiru E Ekechukwu, Mahamoudou Toure, Doug Paton, Mamadou Coulibaly, Sékou F Traoré, Frédéric Tripet

Open Access Research

Accuracy of Pf HRP2 versus Pf-pLDH antigen detection by malaria rapid diagnostic tests in hospitalized children in a seasonal hyperendemic malaria transmission area in Burkina Faso

Jessica Maltha, Issa Guiraud, Palpouguini Lompo, Bérenger Kaboré, Philippe Gillet, Chris Van Geet, Halidou Tinto, Jan Jacobs

Open Access Research

High prevalence of asymptomatic malaria in south-eastern Bangladesh

Peter Starzengruber, Hans-Peter Fuehrer, Benedikt Ley, Kamala Thriemer, Paul Swoboda, Verena Elisabeth Habler, Mariella Jung, Wolfgang Graninger, Wasif A Khan, Rashidul Haque, Harald Noedl

Open Access Research

Four years’ monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border

Papichaya Phompradit, Poonuch Muhamad, Raewadee Wisedpanichkij, Wanna Chaijaroenkul, Kesara Na-Bangchang

Open Access Research

Anti-malarial activity and HS-SPME-GC-MS chemical profiling of Plinia cerrocampanensis leaf essential oil

Armando A Durant, Candelario Rodríguez, Liuris Herrera, Alejandro Almanza, Ana I Santana, Carmenza Spadadora, Mahabir P Gupta

Open Access Research

Factors affecting uptake of optimal doses of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy in six districts of Tanzania

Amon Exavery, Godfrey Mbaruku, Selemani Mbuyita, Ahmed Makemba, Iddajovana P Kinyonge, Hadija Kweka

Open Access Research

A morphometric and histological study of placental malaria shows significant changes to villous architecture in both Plasmodium falciparum and Plasmodium vivax infection

Sethawud Chaikitgosiyakul, Marcus J Rijken, Atis Muehlenbachs, Sue J Lee, Urai Chaisri, Parnpen Viriyavejakul, Gareth D Turner, Emsri Pongponratn, Francois Nosten, Rose McGready

Open Access Research

Polymorphism of the merozoite surface protein-1 block 2 region in Plasmodium falciparum isolates from Mauritania

Mohamed Salem O Ahmedou Salem, Magatte Ndiaye, Mohamed OuldAbdallahi, Khadijetou M Lekweiry, Hervé Bogreau, Lassana Konaté, Babacar Faye, Oumar Gaye, Ousmane Faye, Ali O Mohamed Salem O Boukhary

Open Access Research

Entomological and parasitological impacts of indoor residual spraying with DDT, alphacypermethrin and deltamethrin in the western foothill area of Madagascar

Jocelyn Ratovonjato, Milijaona Randrianarivelojosia, Maroafy E Rakotondrainibe, Vaomalala Raharimanga, Lala Andrianaivolambo, Gilbert Le Goff, Christophe Rogier, Frédéric Ariey, Sébastien Boyer, Vincent Robert

Open Access Research

Early parasite clearance following artemisinin-based combination therapy among Ugandan children with uncomplicated Plasmodium falciparum malaria

Mary K Muhindo, Abel Kakuru, Prasanna Jagannathan, Ambrose Talisuna, Emmanuel Osilo, Francis Orukan, Emmanuel Arinaitwe, Jordan W Tappero, Frank Kaharuza, Moses R Kamya, Grant Dorsey

Open Access Case report

Idiopathic acute myocarditis during treatment for controlled human malaria infection: a case report

Maurits PA van Meer, Guido JH Bastiaens, Mohamed Boulaksil, Quirijn de Mast, Anusha Gunasekera, Stephen L Hoffman, Gheorghe Pop, André JAM van der Ven, Robert W Sauerwein

Open Access Research

Insecticide resistance mechanisms associated with different environments in the malaria vector Anopheles gambiae: a case study in Tanzania

Theresia E Nkya, Idir Akhouayri, Rodolphe Poupardin, Bernard Batengana, Franklin Mosha, Stephen Magesa, William Kisinza, Jean-Philippe David

Open Access Research

Analysis of pfhrp2 genetic diversity in Senegal and implications for use of rapid diagnostic tests

Awa B Deme, Daniel J Park, Amy K Bei, Ousmane Sarr, Aida Sadikh Badiane, Papa El Hadji Omar Gueye, Ambroise Ahouidi, Omar Ndir, Souleymane Mboup, Dyann F Wirth, Daouda Ndiaye, Sarah K Volkman

Open Access Obituary

Mario Coluzzi (1938–2012)

Jeffrey R Powell, Nora J Besansky, Alessandra della Torre, Vincenzo Petrarca

Open Access Research

Long-lasting control of Anopheles arabiensis by a single spray application of micro-encapsulated pirimiphos-methyl (Actellic® 300 CS)

Richard M Oxborough, Jovin Kitau, Rebecca Jones, Emmanuel Feston, Johnson Matowo, Franklin W Mosha, Mark W Rowland

Open Access Research

Parasite clearance following treatment with sulphadoxine-pyrimethamine for intermittent preventive treatment in Burkina-Faso and Mali: 42-day in vivo follow-up study

Sheick O Coulibaly, Kassoum Kayentao, Steve Taylor, Etienne A Guirou, Carole Khairallah, Nouhoun Guindo, Moussa Djimde, Richard Bationo, Alamissa Soulama, Edgar Dabira, Binta Barry, Moussa Niangaly, Hammadoun Diakite, Sidiki Konate, Mohamed Keita, Boubacar Traore, Steve R Meshnick, Pascal Magnussen, Ogobara K Doumbo, Feiko O ter Kuile

Open Access Research

Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children aged less than five years: results of an open-label, randomized, single-centre study

Bernhards R Ogutu, Kevin O Onyango, Nelly Koskei, Edgar K Omondi, John M Ongecha, Godfrey A Otieno, Charles Obonyo, Lucas Otieno, Fredrick Eyase, Jacob D Johnson, Raymond Omollo, Douglas J Perkins, Willis Akhwale, Elizabeth Juma

Open Access Research

A qualitative study to assess community barriers to malaria mass drug administration trials in the Gambia

Natalie J Dial, Serign J Ceesay, Roly D Gosling, Umberto D’Alessandro, Kimberly A Baltzell

Open Access Research

Eliminating malaria in Malaysia: the role of partnerships between the public and commercial sectors in Sabah

Kelly C Sanders, Christina Rundi, Jenarun Jelip, Yusof Rashman, Cara Smith Gueye, Roly D Gosling

Open Access Research

Field evaluation of the photo-induced electron transfer fluorogenic primers (PET) real-time PCR for the detection of Plasmodium falciparum in Tanzania

Eldin Talundzic, Mussa Maganga, Irene M Masanja, David S Peterson, Venkatachalam Udhayakumar, Naomi W Lucchi

Open Access Reviewer acknowledgement

Reviewer acknowledgement 2013

Marcel Hommel

Open Access Methodology

The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic studies in mice

Efrem T Abay, Jan H van der Westhuizen, Kenneth J Swart, Liezl Gibhard, Matshawandile Tukulula, Kelly Chibale, Lubbe Wiesner

Open Access Research

Malaria in overseas labourers returning to China: an analysis of imported malaria in Jiangsu Province, 2001–2011

Yaobao Liu, Michelle S Hsiang, Huayun Zhou, Weiming Wang, Yuanyuan Cao, Roly D Gosling, Jun Cao, Qi Gao

Open Access Research

Use of a three-band HRP2/pLDH combination rapid diagnostic test increases diagnostic specificity for falciparum malaria in Ugandan children

Michael Hawkes, Andrea L Conroy, Robert O Opoka, Sophie Namasopo, W Conrad Liles, Chandy C John, Kevin C Kain

Open Access Research

Malaria indicator survey 2009, South Sudan: baseline results at household level

Margaret B Eyobo, Adwok C Awur, Gregory Wani, Ahmed I Julla, Constantino D Remijo, Bakhit Sebit, Robert Azairwe, Othwonh Thabo, Edward Bepo, Richard L Lako, Lul Riek, Emmanuel Chanda

Open Access Research

Introducing the concept of a new pre-referral treatment for severely ill febrile children at community level: a sociological approach in Guinea-Bissau

Audrey Vermeersch, Anaëlle Libaud-Moal, Amabelia Rodrigues, Nicholas J White, Piero Olliaro, Melba Gomes, Elizabeth A Ashley, Pascal Millet

Open Access Research

Communicating the AMFm message: exploring the effect of communication and training interventions on private for-profit provider awareness and knowledge related to a multi-country anti-malarial subsidy intervention

Barbara A Willey, Sarah Tougher, Yazoume Ye, Andrea G Mann, Rebecca Thomson, Idrissa A Kourgueni, John H Amuasi, Ruilin Ren, Marilyn Wamukoya, Sergio Torres Rueda, Mark Taylor, Moctar Seydou, Samuel Blay Nguah, Salif Ndiaye, Blessing Mberu, Oumarou Malam, Admirabilis Kalolella, Elizabeth Juma, Boniface Johanes, Charles Festo, Graciela Diap, Didier Diallo, Katia Bruxvoort, Daniel Ansong, Abdinasir Amin, Catherine A Adegoke, Kara Hanson, Fred Arnold, Catherine Goodman

Open Access Research

Lessons learned from the use of HRP-2 based rapid diagnostic test in community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso

Alfred B Tiono, Alphonse Ouédraogo, Amidou Diarra, Sam Coulibaly, Issiaka Soulama, Amadou T Konaté, Aïssata Barry, Amitava Mukhopadhyay, Sodiomon B Sirima, Kamal Hamed

Open Access Research

Field study site selection, species abundance and monthly distribution of anopheline mosquitoes in the northern Kruger National Park, South Africa

Givemore Munhenga, Basil D Brooke, Belinda Spillings, Leyya Essop, Richard H Hunt, Stephen Midzi, Danny Govender, Leo Braack, Lizette L Koekemoer

Open Access Research

Integrating rapid risk mapping and mobile phone call record data for strategic malaria elimination planning

Andrew J Tatem, Zhuojie Huang, Clothilde Narib, Udayan Kumar, Deepika Kandula, Deepa K Pindolia, David L Smith, Justin M Cohen, Bonita Graupe, Petrina Uusiku, Christopher Lourenço

Open Access Review

Declining malaria in Africa: improving the measurement of progress

Peter W Gething, Katherine E Battle, Samir Bhatt, David L Smith, Thomas P Eisele, Richard E Cibulskis, Simon I Hay

Open Access Research

The bionomics of the malaria vector Anopheles farauti in Northern Guadalcanal, Solomon Islands: issues for successful vector control

Hugo Bugoro, Jeffery L Hii, Charles Butafa, Charlie Iro’ofa, Allen Apairamo, Robert D Cooper, Cheng-Chen Chen, Tanya L Russell

Open Access Research

Low genetic diversity and functional constraint in loci encoding Plasmodium vivax P12 and P38 proteins in the Colombian population

Johanna Forero-Rodríguez, Diego Garzón-Ospina, Manuel A Patarroyo

Open Access Research

Diversity and population structure of Plasmodium falciparum in Thailand based on the spatial and temporal haplotype patterns of the C-terminal 19-kDa domain of merozoite surface protein-1

Phumin Simpalipan, Sittiporn Pattaradilokrat, Napaporn Siripoon, Aree Seugorn, Morakot Kaewthamasorn, Robert DJ Butcher, Pongchai Harnyuttanakorn

Open Access Research

Evaluation of three rapid diagnostic tests for the detection of human infections with Plasmodium knowlesi

Deshka Foster, Janet Cox-Singh, Dayang SA Mohamad, Sanjeev Krishna, Pek P Chin, Balbir Singh

Open Access Review

Mass primaquine treatment to eliminate vivax malaria: lessons from the past

Anatoly Kondrashin, Alla M Baranova, Elizabeth A Ashley, Judith Recht, Nicholas J White, Vladimir P Sergiev

Open Access Research

Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections

Jacklin F Mosha, Hugh JW Sturrock, Brian Greenwood, Colin J Sutherland, Nahla B Gadalla, Sharan Atwal, Simon Hemelaar, Joelle M Brown, Chris Drakeley, Gibson Kibiki, Teun Bousema, Daniel Chandramohan, Roland D Gosling

Open Access Research

Patient-, health worker-, and health facility-level determinants of correct malaria case management at publicly funded health facilities in Malawi: results from a nationally representative health facility survey

Laura C Steinhardt, Jobiba Chinkhumba, Adam Wolkon, Madalitso Luka, Misheck Luhanga, John Sande, Jessica Oyugi, Doreen Ali, Don Mathanga, Jacek Skarbinski

Open Access Research

Behavioural divergence of sympatric Anopheles funestus populations in Burkina Faso

Wamdaogo M Guelbeogo, N’Fale Sagnon, Fang Liu, Nora J Besansky, Carlo Costantini

Open Access Case report

First case of a naturally acquired human infection with Plasmodium cynomolgi

Thuy H Ta, Shamilah Hisam, Marta Lanza, Adela I Jiram, NorParina Ismail, José M Rubio

Open Access Research

Clinical complications of G6PD deficiency in Latin American and Caribbean populations: systematic review and implications for malaria elimination programmes

Wuelton M Monteiro, Gabriel P Franca, Gisely C Melo, Amanda LM Queiroz, Marcelo Brito, Henry M Peixoto, Maria Regina F Oliveira, Gustavo AS Romero, Quique Bassat, Marcus VG Lacerda

Open Access Methodology

A rapid sensitive, flow cytometry-based method for the detection of Plasmodium vivax-infected blood cells

Wanlapa Roobsoong, Steven P Maher, Nattawan Rachaphaew, Samantha J Barnes, Kim C Williamson, Jetsumon Sattabongkot, John H Adams

Open Access Research

Genetic variation and recurrent parasitaemia in Peruvian Plasmodium vivax populations

Andrea M McCollum, Valeria Soberon, Carola J Salas, Meddly L Santolalla, Venkatachalam Udhayakumar, Ananias A Escalante, Paul CF Graf, Salomon Durand, Cesar Cabezas, David J Bacon

Open Access Review

On the road to eliminate malaria in Sri Lanka: lessons from history, challenges, gaps in knowledge and research needs

Nadira D Karunaweera, Gawrie NL Galappaththy, Dyann F Wirth

Open Access Research

SMS messages increase adherence to rapid diagnostic test results among malaria patients: results from a pilot study in Nigeria

Sepideh Modrek, Eric Schatzkin, Anna De La Cruz, Chinwoke Isiguzo, Ernest Nwokolo, Jennifer Anyanti, Chinazo Ujuju, Dominic Montagu, Jenny Liu

Open Access Research

Mefloquine safety and tolerability in pregnancy: a systematic literature review

Raquel González, Urban Hellgren, Brian Greenwood, Clara Menéndez

Open Access Commentary

Were medicine quality and pharmaceutical management contributing factors in diminishing artemisinin efficacy in Guyana and Suriname?

Victor S Pribluda, Lawrence Evans III, Edgar Barillas, John Marmion, Patrick Lukulay, Jaime Chang

Open Access Case report

Vivax malaria in an Amazonian child with dilated cardiomyopathy

Antonio C Martins, Jamille B Lins, Luana MN Santos, Licia N Fernandes, Rosely S Malafronte, Teresa C Maia, Melissa CV Ribera, Ricardo B Ribera, Monica da Silva-Nunes

Open Access Research

Evaluation of a universal long-lasting insecticidal net (LLIN) distribution campaign in Ghana: cost effectiveness of distribution and hang-up activities

Lucy Smith Paintain, Elizabeth Awini, Sheila Addei, Vida Kukula, Christian Nikoi, Doris Sarpong, Alfred Kwesi Manyei, Daniel Yayemain, Etienne Rusamira, Josephine Agborson, Aba Baffoe-Wilmot, Constance Bart-Plange, Anirban Chatterjee, Margaret Gyapong, Lindsay Mangham-Jefferies

Open Access Research

Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti-malarials and gene characterization in Rondônia, West Amazon, Brazil

Anna Caroline C Aguiar, Dhelio B Pereira, Nayra S Amaral, Luiz De Marco, Antoniana U Krettli

Open Access Methodology

Cytometric measurement of in vitro inhibition of Plasmodium falciparum field isolates by drugs: a new approach for re-invasion inhibition study

Marie Louise Varela, Romy Razakandrainibe, Delphine Aldebert, Jean Christophe Barale, Ronan Jambou

Open Access Research

Plasmodium falciparum clearance in clinical studies of artesunate-amodiaquine and comparator treatments in sub-Saharan Africa, 1999–2009

Julien Zwang, Grant Dorsey, Andreas Mårtensson, Umberto d’Alessandro, Jean-Louis Ndiaye, Corine Karema, Abdoulaye Djimde, Philippe Brasseur, Sodiomon B Sirima, Piero Olliaro

Open Access Research

Submicroscopic infection of placenta by Plasmodium produces Th1/Th2 cytokine imbalance, inflammation and hypoxia in women from north-west Colombia

Olga M Agudelo, Beatriz H Aristizabal, Stephanie K Yanow, Eliana Arango, Jaime Carmona-Fonseca, Amanda Maestre

Open Access Research

Information use and plasticity in the reproductive decisions of malaria parasites

Lucy M Carter, Petra Schneider, Sarah E Reece

Open Access Research

Impact of long-lasting, insecticidal nets on anaemia and prevalence of Plasmodium falciparum among children under five years in areas with highly resistant malaria vectors

Filémon T Tokponnon, Aurore Hounto Ogouyémi, Yolande Sissinto, Arthur Sovi, Virgile Gnanguenon, Sylvie Cornélie, Adicath Adéola Adéothy, Razaki Ossè, Abel Wakpo, Dina Gbénou, Mariam Oke, Dorothée Kinde-Gazard, Immo Kleinschmidt, Martin C Akogbeto, Achille Massougbodji

Open Access Research

“People will say that I am proud”: a qualitative study of barriers to bed net use away from home in four Ugandan districts

April Monroe, Steven A Harvey, Yukyan Lam, Denis Muhangi, Dana Loll, Asaph Turinde Kabali, Rachel Weber

Open Access Research

High prevalence of pfcrt-CVIET haplotype in isolates from asymptomatic and symptomatic patients in south-central Oromia, Ethiopia

Lemu Golassa, Nizar Enweji, Berhanu Erko, Abraham Aseffa, Göte Swedberg

Open Access Research

Biting by Anopheles funestus in broad daylight after use of long-lasting insecticidal nets: a new challenge to malaria elimination

Seynabou Sougoufara, Seynabou Mocote Diédhiou, Souleymane Doucouré, Nafissatou Diagne, Pape Mbacké Sembène, Myriam Harry, Jean-François Trape, Cheikh Sokhna, Mamadou Ousmane Ndiath

Open Access Case report

Mixed-species Plasmodium falciparum and Plasmodium ovale malaria in a paediatric returned traveller

Heather Senn, Nadia Alattas, Andrea K Boggild, Shaun K Morris

Open Access Research

Imported falciparum malaria among adults requiring intensive care: analysis of the literature

Michael Marks, Margaret Armstrong, David Walker, Tom Doherty

Open Access Review

The potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoids

Fidele Ntie-Kang, Pascal Amoa Onguéné, Lydia L Lifongo, Jean Claude Ndom, Wolfgang Sippl, Luc Meva’a Mbaze

Open Access Research

Dramatic declines in seropositivity as determined with crude extracts of Plasmodium falciparum schizonts between 2000 and 2010 in Dielmo and Ndiop, Senegal

Fode Diop, Vincent Richard, Babacar Diouf, Cheikh Sokhna, Nafissatou Diagne, Jean-François Trape, Michel Matar Faye, Adama Tall, Gora Diop, Aissatou Toure Balde

Open Access Research

Quality of life and the risk of contracting malaria by multivariate analysis in the Brazilian Amazon region

Sergio GL Junior, Vanessa MS Pamplona, Tereza CO Corvelo, Edson MLS Ramos

Open Access Research

Phenotypic characterization of Plasmodium berghei responsive CD8+ T cells after immunization with live sporozoites under chloroquine cover

Clara Brando, Jason H Richardson, Jittawadee Murphy, Christian F Ockenhouse, Edwin Kamau

Open Access Research

Relationship of regulatory T cells to Plasmodium falciparum malaria symptomatology in a hypoendemic region

Katherine J Torres, Elizabeth Villasis, Jorge Bendezú, José Chauca, Joseph M Vinetz, Dionicia Gamboa

Open Access Research

Modelling the effects of weather and climate on malaria distributions in West Africa

Ali Arab, Monica C Jackson, Cezar Kongoli

Open Access Research

Habitat discrimination by gravid Anopheles gambiae sensu lato – a push-pull system

Manuela Herrera-Varela, Jenny Lindh, Steven W Lindsay, Ulrike Fillinger

Open Access Research

Chloroquine efficacy studies confirm drug susceptibility of Plasmodium vivax in Chennai, India

Sneh Shalini, Saumyadripta Chaudhuri, Patrick L Sutton, Neelima Mishra, Nalini Srivastava, Joseph K David, K John Ravindran, Jane M Carlton, Alex Eapen

Open Access Research

Asymptomatic Plasmodium falciparum infection is associated with anaemia in pregnancy and can be more cost-effectively detected by rapid diagnostic test than by microscopy in Kinshasa, Democratic Republic of the Congo

Junior R Matangila, Jean Lufuluabo, Axel L Ibalanky, Raquel A Inocêncio da Luz, Pascal Lutumba, Jean-Pierre Van Geertruyden

Open Access Research

Plasma advanced oxidative protein products are associated with anti-oxidative stress pathway genes and malaria in a longitudinal cohort

Guicheng Zhang, Oleksii A Skorokhod, Siew-Kim Khoo, Ruth Aguilar, Selma Wiertsema, Augusto J Nhabomba, Tiziana Marrocco, Michelle McNamara-Smith, Maria Nelia Manaca, Arnoldo Barbosa, Llorenç Quintó, Catherine M Hayden, Jack Goldblatt, Caterina Guinovart, Pedro L Alonso, Carlota Dobaño, Evelin Schwarzer, Peter N LeSouëf

Open Access Research

Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum

Marije C Behet, Lander Foquet, Geert-Jan van Gemert, Else M Bijker, Philip Meuleman, Geert Leroux-Roels, Cornelus C Hermsen, Anja Scholzen, Robert W Sauerwein

Open Access Research

PCR targeting Plasmodium mitochondrial genome of DNA extracted from dried blood on filter paper compared to whole blood

Gro EA Strøm, Sabrina Moyo, Maulidi Fataki, Nina Langeland, Bjørn Blomberg

Open Access Research

Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections

Qigui Li, Michael O’Neil, Lisa Xie, Diana Caridha, Qiang Zeng, Jing Zhang, Brandon Pybus, Mark Hickman, Victor Melendez

Open Access Research

Repositioning: the fast track to new anti-malarial medicines?

Julie Lotharius, Francisco Javier Gamo-Benito, Iñigo Angulo-Barturen, Julie Clark, Michele Connelly, Santiago Ferrer-Bazaga, Tanya Parkinson, Pavithra Viswanath, Balachandra Bandodkar, Nikhil Rautela, Sowmya Bharath, Sandra Duffy, Vicky M Avery, Jörg J Möhrle, R Kiplin Guy, Timothy Wells

Open Access Research

Comparison of an assumed versus measured leucocyte count in parasite density calculations in Papua New Guinean children with uncomplicated malaria

Moses Laman, Brioni R Moore, John Benjamin, Nixon Padapu, Nandao Tarongka, Peter Siba, Inoni Betuela, Ivo Mueller, Leanne J Robinson, Timothy M E Davis

Open Access Methodology

Magnetic isolation of Plasmodium falciparum schizonts iRBCs to generate a high parasitaemia and synchronized in vitro culture

Lydia Mata-Cantero, Maria J Lafuente, Laura Sanz, Manuel S Rodriguez

Open Access Case study

The impact of clinical research activities on communities in rural Africa: the development of the Clinical Research Unit of Nanoro (CRUN) in Burkina Faso

Halidou Tinto, Innocent Valea, Hermann Sorgho, Marc Christian Tahita, Maminata Traore, Biébo Bihoun, Issa Guiraud, Hervé Kpoda, Jérémi Rouamba, Sayouba Ouédraogo, Palpouguini Lompo, Sandrine Yara, William Kabore, Jean-Bosco Ouédraogo, Robert Tinga Guiguemdé, Fred N Binka, Bernhards Ogutu

Open Access Research

Parasite densities modulate susceptibility of mice to cerebral malaria during co-infection with Schistosoma japonicum and Plasmodium berghei

Mei-lian Wang, Yong-hui Feng, Wei Pang, Zan-mei Qi, Ying Zhang, Ya-jun Guo, En-jie Luo, Ya-ming Cao

Open Access Research

Distribution of pfmdr1 polymorphisms in Plasmodium falciparum isolated from Southern Thailand

Mathirut Mungthin, Somchai Intanakom, Nantana Suwandittakul, Preeyaporn Suida, Sakultip Amsakul, Naruemon Sitthichot, Suwich Thammapalo, Saovanee Leelayoova

Open Access Research

Identification of heat shock factor binding protein in Plasmodium falciparum

Syed K Sayeed, Varun Shah, Shweta Chaubey, Meetali Singh, Shuba V Alampalli, Utpal S Tatu

Open Access Research

Impact of age of first exposure to Plasmodium falciparum on antibody responses to malaria in children: a randomized, controlled trial in Mozambique

Augusto J Nhabomba, Caterina Guinovart, Alfons Jiménez, Maria N Manaca, Llorenç Quintó, Pau Cisteró, Ruth Aguilar, Arnoldo Barbosa, Mauricio H Rodríguez, Quique Bassat, John J Aponte, Alfredo Mayor, Chetan E Chitnis, Pedro L Alonso, Carlota Dobaño

Open Access Research

Development of a colloidal gold-based lateral flow dipstick immunoassay for rapid qualitative and semi-quantitative analysis of artesunate and dihydroartemisinin

Lishan He, Tiegui Nan, Yongliang Cui, Suqin Guo, Wei Zhang, Rui Zhang, Guiyu Tan, Baomin Wang, Liwang Cui

Open Access Research

Monitoring, characterization and control of chronic, symptomatic malaria infections in rural Zambia through monthly household visits by paid community health workers

Busiku Hamainza, Hawela Moonga, Chadwick H Sikaala, Mulakwa Kamuliwo, Adam Bennett, Thomas P Eisele, John Miller, Aklilu Seyoum, Gerry F Killeen

Open Access Research

Early malaria resurgence in pre-elimination areas in Kokap Subdistrict, Kulon Progo, Indonesia

E Elsa Herdiana Murhandarwati, Anis Fuad, Mubarika DF Nugraheni, Sulistyawati, Mahardika A Wijayanti, Barandi S Widartono, Ting-Wu Chuang

Open Access Research

An experimental hut study to quantify the effect of DDT and airborne pyrethroids on entomological parameters of malaria transmission

Sheila B Ogoma, Lena M Lorenz, Hassan Ngonyani, Robert Sangusangu, Mohammed Kitumbukile, Masoudi Kilalangongono, Emmanuel T Simfukwe, Anton Mseka, Edgar Mbeyela, Deogratius Roman, Jason Moore, Katharina Kreppel, Marta F Maia, Sarah J Moore

Open Access Research

Mind the gaps - the epidemiology of poor-quality anti-malarials in the malarious world - analysis of the WorldWide Antimalarial Resistance Network database

Patricia Tabernero, Facundo M Fernández, Michael Green, Philippe J Guerin, Paul N Newton

Open Access Research

Using mobile phone text messaging for malaria surveillance in rural Kenya

Sophie Githinji, Samwel Kigen, Dorothy Memusi, Andrew Nyandigisi, Andrew Wamari, Alex Muturi, George Jagoe, René Ziegler, Robert W Snow, Dejan Zurovac

Open Access Research

Transmission of malaria in relation to distribution and coverage of long-lasting insecticidal nets in central Côte d’Ivoire

Allassane F Ouattara, Mamadou Dagnogo, Edi AV Constant, Moussa Koné, Giovanna Raso, Marcel Tanner, Piero L Olliaro, Jürg Utzinger, Benjamin G Koudou

Open Access Research

Geographical variation in Plasmodium vivax relapse

Katherine E Battle, Markku S Karhunen, Samir Bhatt, Peter W Gething, Rosalind E Howes, Nick Golding, Thomas P Van Boeckel, Jane P Messina, G Dennis Shanks, David L Smith, J Kevin Baird, Simon I Hay

Open Access Research

Limitations of haemozoin-based diagnosis of Plasmodium falciparum using dark-field microscopy

Charles Delahunt, Matthew P Horning, Benjamin K Wilson, Joshua L Proctor, Michael C Hegg

Open Access Research

The prevalence of glucose-6-phosphate dehydrogenase deficiency in Gambian school children

Joseph Okebe, Alfred Amambua-Ngwa, Jason Parr, Sei Nishimura, Melissa Daswani, Ebako N Takem, Muna Affara, Serign J Ceesay, Davis Nwakanma, Umberto D’Alessandro

Open Access Research

Molecular characterization of Plasmodium falciparum uracil-DNA glycosylase and its potential as a new anti-malarial drug target

Thidarat Suksangpleng, Ubolsree Leartsakulpanich, Saengduen Moonsom, Saranya Siribal, Usa Boonyuen, George E Wright, Porntip Chavalitshewinkoon-Petmitr

Open Access Research

Timelier notification and action with mobile phones–towards malaria elimination in South Africa

Vanessa Quan, Anette Hulth, Gerdalize Kok, Lucille Blumberg

Open Access Research

High levels of sulphadoxine-pyrimethamine resistance Pfdhfr-Pfdhps quintuple mutations: a cross sectional survey of six regions in Tanzania

Sungwa I Matondo, Godfrey S Temba, Adelaida A Kavishe, Julius S Kauki, Akili Kalinga, Marco van Zwetselaar, Hugh Reyburn, Reginald A Kavishe

Open Access Research

Evidence for significant influence of host immunity on changes in differential blood count during malaria

Nicole Berens-Riha, Inge Kroidl, Mirjam Schunk, Martin Alberer, Marcus Beissner, Michael Pritsch, Arne Kroidl, Günter Fröschl, Ingrid Hanus, Gisela Bretzel, Frank von Sonnenburg, Hans Dieter Nothdurft, Thomas Löscher, Karl-Heinz Herbinger

Open Access Methodology

Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda

Maxwell Kilama, David L Smith, Robert Hutchinson, Ruth Kigozi, Adoke Yeka, Geoff Lavoy, Moses R Kamya, Sarah G Staedke, Martin J Donnelly, Chris Drakeley, Bryan Greenhouse, Grant Dorsey, Steve W Lindsay

Open Access Research

Perceptions and recommendations by scientists for a potential release of genetically modified mosquitoes in Nigeria

Patricia N Okorie, John M Marshall, Onoja M Akpa, Olusegun G Ademowo

Open Access Case report

Oligohydramnios in a pregnant Pakistani woman with Plasmodium vivax malaria

Nicolò Binello, Enrico Brunetti, Federico Cattaneo, Raffaella Lissandrin, Antonello Malfitano

Open Access Research

Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum

Talita PC Chierrito, Anna CC Aguiar, Isabel M de Andrade, Isabela P Ceravolo, Regina AC Gonçalves, Arildo JB de Oliveira, Antoniana U Krettli

Open Access Research

Biochemical and functional characterization of Plasmodium falciparum GTP cyclohydrolase I

Krittikorn Kümpornsin, Namfon Kotanan, Pornpimol Chobson, Theerarat Kochakarn, Piyaporn Jirawatcharadech, Peera Jaru-ampornpan, Yongyuth Yuthavong, Thanat Chookajorn

Open Access Methodology

Use of a semi-field system to evaluate the efficacy of topical repellents under user conditions provides a disease exposure free technique comparable with field data

Onyango Sangoro, Dickson Lweitojera, Emmanuel Simfukwe, Hassan Ngonyani, Edgar Mbeyela, Daniel Lugiko, Japhet Kihonda, Marta Maia, Sarah Moore

Open Access Research

Effective autodissemination of pyriproxyfen to breeding sites by the exophilic malaria vector Anopheles arabiensis in semi-field settings in Tanzania

Dickson Lwetoijera, Caroline Harris, Samson Kiware, Stefan Dongus, Gregor J Devine, Philip J McCall, Silas Majambere

Open Access Research

Sensitivity of fever for diagnosis of clinical malaria in a Kenyan area of unstable, low malaria transmission

Albino L Mutanda, Priscah Cheruiyot, James S Hodges, George Ayodo, Wilson Odero, Chandy C John

Open Access Research

Community mobilization for malaria elimination: application of an open space methodology in Ruhuha sector, Rwanda

Chantal Marie Ingabire, Jane Alaii, Emmanuel Hakizimana, Fredrick Kateera, Daniel Muhimuzi, Ingmar Nieuwold, Karsten Bezooijen, Stephen Rulisa, Nadine Kaligirwa, Claude Muvunyi, Constantianus JM Koenraadt, Leon Mutesa, Michele Van Vugt, Bart Van Den Borne

Open Access Research

High burden of malaria following scale-up of control interventions in Nchelenge District, Luapula Province, Zambia

Victor M Mukonka, Emmanuel Chanda, Ubydul Haque, Mulakwa Kamuliwo, Gabriel Mushinge, Jackson Chileshe, Kennedy A Chibwe, Douglas E Norris, Modest Mulenga, Mike Chaponda, Mbanga Muleba, Gregory E Glass, William J Moss

Open Access Research

Socioeconomic factors, attitudes and practices associated with malaria prevention in the coastal plain of Chiapas, Mexico

Merit Mora-Ruiz, R Patricia Penilla, José G Ordóñez, Alma D López, Francisco Solis, José Luis Torres-Estrada, Américo D Rodríguez

Open Access Research

Knowledge, attitudes and practices of malaria in Colombia

David A Forero, Pablo E Chaparro, Andres F Vallejo, Yoldy Benavides, Juan B Gutiérrez, Myriam Arévalo-Herrera, Sócrates Herrera

Open Access Research

High proportion of knowlesi malaria in recent malaria cases in Malaysia

Ruhani Yusof, Yee Ling Lau, Rohela Mahmud, Mun Yik Fong, Jenarun Jelip, Hie Ung Ngian, Sahlawati Mustakim, Hani Mat Hussin, Noradilah Marzuki, Marlindawati Mohd Ali

Open Access Research

Screening for adulticidal activity against Anopheles arabiensis in ten plants used as mosquito repellent in South Africa

Edison J Mavundza, Rajendra Maharaj, Jude C Chukwujekwu, Jeffrey F Finnie, Johannes Van Staden

Open Access Research

Application of loop analysis for evaluation of malaria control interventions

Junko Yasuoka, Masamine Jimba, Richard Levins

Open Access Research

Antenatal care visit attendance, intermittent preventive treatment during pregnancy (IPTp) and malaria parasitaemia at delivery

Judith K Anchang-Kimbi, Eric A Achidi, Tobias O Apinjoh, Regina N Mugri, Hanesh Fru Chi, Rolland B Tata, Blaise Nkegoum, Joseph-Marie N Mendimi, Eva Sverremark-Ekström, Marita Troye-Blomberg

Open Access Research

Alterations in mosquito behaviour by malaria parasites: potential impact on force of infection

Lauren J Cator, Penelope A Lynch, Matthew B Thomas, Andrew F Read

Open Access Research

Molasses as a source of carbon dioxide for attracting the malaria mosquitoes Anopheles gambiae and Anopheles funestus

Collins K Mweresa, Philemon Omusula, Bruno Otieno, Joop JA van Loon, Willem Takken, Wolfgang R Mukabana

Open Access Research

Comparison of Giemsa microscopy with nested PCR for the diagnosis of malaria in North Gondar, north-west Ethiopia

Abebe Alemu, Hans-Peter Fuehrer, Gebeyaw Getnet, Afework Kassu, Sisay Getie, Harald Noedl

Open Access Research

Evaluating the feasibility of using insecticide quantification kits (IQK) for estimating cyanopyrethroid levels for indoor residual spraying in Vanuatu

Tanya L Russell, John C Morgan, Hanafy Ismail, Harparkash Kaur, Teunis Eggelte, Folasade Oladepo, James Amon, Janet Hemingway, Harry Iata, Mark JI Paine

Open Access Methodology

Air temperature suitability for Plasmodium falciparum malaria transmission in Africa 2000-2012: a high-resolution spatiotemporal prediction

Daniel J Weiss, Samir Bhatt, Bonnie Mappin, Thomas P Van Boeckel, David L Smith, Simon I Hay, Peter W Gething

Open Access Methodology

Nested PCR detection of malaria directly using blood filter paper samples from epidemiological surveys

Peipei Li, Zhenjun Zhao, Ying Wang, Hua Xing, Daniel M Parker, Zhaoqing Yang, Elizabeth Baum, Wenli Li, Jetsumon Sattabongkot, Jeeraphat Sirichaisinthop, Shuying Li, Guiyun Yan, Liwang Cui, Qi Fan

Open Access Research

Acceptance of a malaria vaccine by caregivers of sick children in Kenya

David I Ojakaa, Jordan D Jarvis, Mary I Matilu, Sylla Thiam

Open Access Research

Glomerular changes and alterations of zonula occludens-1 in the kidneys of Plasmodium falciparum malaria patients

Benjamas Wichapoon, Chuchard Punsawad, Urai Chaisri, Parnpen Viriyavejakul

Open Access Research

Magnetic resonance imaging of the brain in adults with severe falciparum malaria

Richard James Maude, Frederik Barkhof, Mahtab Uddin Hassan, Aniruddha Ghose, Amir Hossain, M Abul Faiz, Ehsan Choudhury, Rehnuma Rashid, Abdullah Abu Sayeed, Prakaykaew Charunwatthana, Katherine Plewes, Hugh Kingston, Rapeephan Rattanawongnara Maude, Kamolrat Silamut, Nicholas Philip John Day, Nicholas John White, Arjen Mattheus Dondorp

Open Access Methodology

Sample-ready multiplex qPCR assay for detection of malaria

Edwin Kamau, Saba Alemayehu, Karla C Feghali, Dennis W Juma, George M Blackstone, William R Marion, Peter Obare, Bernhards Ogutu, Christian F Ockenhouse

Open Access Research

Rapid diagnostic tests for malaria and health workers’ adherence to test results at health facilities in Zambia

Christine Manyando, Eric M Njunju, Justin Chileshe, Seter Siziya, Clive Shiff

Open Access Methodology

A lab-on-chip for malaria diagnosis and surveillance

Brian J Taylor, Anita Howell, Kimberly A Martin, Dammika P Manage, Walter Gordy, Stephanie D Campbell, Samantha Lam, Albert Jin, Spencer D Polley, Roshini A Samuel, Alexey Atrazhev, Alex J Stickel, Josephine Birungi, Anthony K Mbonye, Linda M Pilarski, Jason P Acker, Stephanie K Yanow

Open Access Research

The contribution of reduction in malaria as a cause of rapid decline of under-five mortality: evidence from the Rufiji Health and Demographic Surveillance System (HDSS) in rural Tanzania

Almamy M Kanté, Rose Nathan, Stéphane Helleringer, Mrema Sigilbert, Francis Levira, Honorati Masanja, Don de Savigny, Salim Abdulla, James F Phillips

Open Access Research

Decision-making on intra-household allocation of bed nets in Uganda: do households prioritize the most vulnerable members?

Yukyan Lam, Steven A Harvey, April Monroe, Denis Muhangi, Dana Loll, Asaph Turinde Kabali, Rachel Weber

Open Access Research

The challenge to avoid anti-malarial medicine stock-outs in an era of funding partners: the case of Tanzania

Inez Mikkelsen-Lopez, Winna Shango, Jim Barrington, Rene Ziegler, Tom Smith, Don deSavigny

Open Access Research

Molecular typing reveals substantial Plasmodium vivax infection in asymptomatic adults in a rural area of Cameroon

Jerome Fru-Cho, Violet V Bumah, Innocent Safeukui, Theresa Nkuo-Akenji, Vincent PK Titanji, Kasturi Haldar

Open Access Research

Characterization of drug resistance associated genetic polymorphisms among Plasmodium falciparum field isolates in Ujjain, Madhya Pradesh, India

Ashish Pathak, Andreas Mårtensson, Sudhir Gawariker, Jagdish Mandliya, Ashish Sharma, Vishal Diwan, Johan Ursing

Open Access Research

A kinetic fluorescence assay reveals unusual features of Ca++ uptake in Plasmodium falciparum-infected erythrocytes

Elizabeth M Zipprer, McKinzie Neggers, Ambuj Kushwaha, Kempaiah Rayavara, Sanjay A Desai

Open Access Research

Long-lasting insecticide-treated bed net ownership and use among children under five years of age following a targeted distribution in central Uganda

Humphrey Wanzira, Adoke Yeka, Ruth Kigozi, Denis Rubahika, Sussann Nasr, Asadu Sserwanga, Moses Kamya, Scott Filler, Grant Dorsey, Laura Steinhardt

Open Access Research

Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort

Dominic Mosha, Festo Mazuguni, Sigilbert Mrema, Esperanca Sevene, Salim Abdulla, Blaise Genton

Open Access Research

Designing and implementing interventions to change clinicians’ practice in the management of uncomplicated malaria: lessons from Cameroon

Olivia A Achonduh, Wilfred F Mbacham, Lindsay Mangham-Jefferies, Bonnie Cundill, Clare Chandler, Joelle Pamen-Ngako, Albertine K Lele, Ignatius C Ndong, Sarah N Ndive, Joel N Ambebila, Barnabas B Orang-Ojong, Theresia N Metoh, Mbuh Akindeh-Nji, Virginia Wiseman

Open Access Research

Analysis of trend of malaria prevalence in south-west Ethiopia: a retrospective comparative study

Lelisa D Sena, Wakgari A Deressa, Ahmed A Ali

Open Access Case report

Uncomplicated Plasmodium vivax malaria in pregnancy associated with mortality from acute respiratory distress syndrome

Rose McGready, Klanarong Wongsaen, Cindy S Chu, Nay Win Tun, Kesinee Chotivanich, Nicholas J White, François Nosten

Open Access Research

Mass distribution of free insecticide-treated nets do not interfere with continuous net distribution in Tanzania

Ikenna C Eze, Karen Kramer, Amina Msengwa, Renata Mandike, Christian Lengeler

Open Access Research

Importance of active case detection in a malaria elimination programme

Renu Wickremasinghe, Sumadhya Deepika Fernando, Janani Thillekaratne, Panduka Mahendra Wijeyaratne, Ananda Rajitha Wickremasinghe

Open Access Research

In vitro interaction of lumefantrine and piperaquine by atorvastatin against Plasmodium falciparum

Jérome Dormoi, Hélène Savini, Rémy Amalvict, Eric Baret, Bruno Pradines

Open Access Research

Frequency and tendency of malaria in Colombia, 1990 to 2011: a descriptive study

Alexandra Porras Ramirez, José Israel Galindo Buitrago, Juan P Pimentel González, Andres Herrera Moráles, Gabriel Carrasquilla

Open Access Research

The epidemiology of malaria and anaemia in the Bonikro mining area, central Côte d’Ivoire

Astrid M Knoblauch, Mirko S Winkler, Colleen Archer, Mark J Divall, Milka Owuor, Raoul M Yapo, Pokou A Yao, Jürg Utzinger

Open Access Research

Laboratory and field evaluation of the impact of washings on the effectiveness of LifeNet®, Olyset® and PermaNet® 2.0 in two areas, where there is a high level of resistance of Anopheles gambiae to pyrethroids, Benin, West Africa

Fiacre R Agossa, Gil G Padonou, Virgile Gnanguenon, Frédéric Oké-Agbo, Jacques Zola-Sahossi, Horace Dègnonvi, Albert Salako, Michel Sèzonlin, Martin C Akogbéto

Open Access Research

Ex vivo anti-malarial drugs sensitivity profile of Plasmodium falciparum field isolates from Burkina Faso five years after the national policy change

Halidou Tinto, Léa N Bonkian, Louis A Nana, Isidore Yerbanga, Moussa Lingani, Adama Kazienga, Innocent Valéa, Hermann Sorgho, Hervé Kpoda, Tinga Robert Guiguemdé, Jean Bosco Ouédraogo, Petronella F Mens, Henk Schallig, Umberto D’Alessandro

Open Access Research

Outcome of artemether-lumefantrine treatment for uncomplicated malaria in HIV-infected adult patients on anti-retroviral therapy

Betty A Maganda, Omary MS Minzi, Appolinary AR Kamuhabwa, Billy Ngasala, Philip G Sasi

Open Access Research

Assessment of the consistency of national-level policies and guidelines for malaria in pregnancy in five African countries

Patricia P Gomez, Julie Gutman, Elaine Roman, Aimee Dickerson, Zandra H Andre, Susan Youll, Erin Eckert, Mary J Hamel

Open Access Research

Effect of malarial infection on haematological parameters in population near Thailand-Myanmar border

Manas Kotepui, Bhukdee Phunphuech, Nuoil Phiwklam, Chaowanee Chupeerach, Suwit Duangmano

Open Access Research

Efficacy of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy, Mansa, Zambia

Kathrine R Tan, Bonnie L Katalenich, Kimberly E Mace, Michael Nambozi, Steve M Taylor, Steven R Meshnick, Ryan E Wiegand, Victor Chalwe, Scott J Filler, Mulakwa Kamuliwo, Allen S Craig

Open Access Research

A genome scan for Plasmodium falciparum malaria identifies quantitative trait loci on chromosomes 5q31, 6p21.3, 17p12, and 19p13

Audrey Brisebarre, Brice Kumulungui, Serge Sawadogo, Alexandre Atkinson, Séverine Garnier, Francis Fumoux, Pascal Rihet

Open Access Research

Participants’ perceptions and understanding of a malaria clinical trial in Bangladesh

Debashish Das, Phaik Yeong Cheah, Fateha Akter, Dulal Paul, Akhterul Islam, Abdullah A Sayeed, Rasheda Samad, Ridwanur Rahman, Amir Hossain, Arjen Dondorp, Nicholas P Day, Nicholas J White, Mahtabuddin Hasan, Aniruddha Ghose, Elizabeth A Ashley, Abul Faiz

Open Access Research

Education and knowledge helps combating malaria, but not degedege: a cross-sectional study in Rufiji, Tanzania

Astrid Onarheim Spjeldnæs, Andrew Y Kitua, Bjørn Blomberg

Open Access Research

Seasonal genetic partitioning in the neotropical malaria vector, Anopheles darlingi

Aline F Angêlla, Patrícia Salgueiro, Luiz HS Gil, José L Vicente, João Pinto, Paulo EM Ribolla

Open Access Research

Challenges in universal coverage and utilization of insecticide-treated bed nets in migrant plantation workers in Myanmar

Myat H Nyunt, Khin M Aye, Myat P Kyaw, Thar T Kyaw, Thaung Hlaing, Kyaw Oo, Ni N Zaw, Thin T Aye, Nechi A San

Open Access Research

Detection of Plasmodium falciparum and Plasmodium vivax subclinical infection in non-endemic region: implications for blood transfusion and malaria epidemiology

Luciana MF Maselli, Debora Levy, Gabriel Z Laporta, Aline M Monteiro, Linah A Fukuya, Maria F Ferreira-da-Cruz, Claudio T Daniel-Ribeiro, Pedro E Dorlhiac-Llacer, Maria Anice M Sallum, Sérgio P Bydlowski

Open Access Research

A cost-effective, community-based, mosquito-trapping scheme that captures spatial and temporal heterogeneities of malaria transmission in rural Zambia

Chadwick H Sikaala, Dingani Chinula, Javan Chanda, Busiku Hamainza, Mulenga Mwenda, Isabel Mukali, Mulakwa Kamuliwo, Neil F Lobo, Aklilu Seyoum, Gerry F Killeen

Open Access Research

Mirincamycin, an old candidate for malaria combination treatment and prophylaxis in the 21st century: in vitro interaction profiles with potential partner drugs in continuous culture and field isolates

Peter Starzengruber, Hans-Peter Fuehrer, Paul Swoboda, Deepa Ganesh, Rashidul Haque, Wasif A Khan, Wolfgang Graninger, Harald Noedl

Open Access Case report

Acute kidney injury associated with Plasmodium malariae infection

Aida S Badiane, Khadim Diongue, Seydou Diallo, Aliou A Ndongo, Cyrille K Diedhiou, Awa B Deme, Diallo Ma, Mouhamadou Ndiaye, Mame C Seck, Therese Dieng, Omar Ndir, Souleymane Mboup, Daouda Ndiaye

Open Access Research

Ultrastructure of the lung in a murine model of malaria-associated acute lung injury/acute respiratory distress syndrome

Elizabeth H Aitken, Elnara M Negri, Renato Barboza, Maria RI Lima, José M Álvarez, Claudio RF Marinho, Elia G Caldini, Sabrina Epiphanio

Open Access Research

Disease-associated QT-shortage versus quinine associated QT-prolongation: age dependent ECG-effects in Ghanaian children with severe malaria

Louise Roggelin, Daniel Pelletier, Josephine N Hill, Torsten Feldt, Steffi Hoffmann, Daniel Ansong, Justice Sylverken, Jürgen Burhenne, Johanna Fischer-Herr, Parisa Mehrfar, Christian Thiel, Gerd D Burchard, Samuel B Nguah, Jakob P Cramer

Open Access Research

Defining the malaria burden in Nchelenge District, northern Zambia using the World Health Organization malaria indicators survey

Michael Nambozi, Phidelis Malunga, Modest Mulenga, Jean-Pierre Van Geertruyden, Umberto D’Alessandro

Open Access Research

Placental infections with histologically confirmed Plasmodium falciparum are associated with adverse birth outcomes in India: a cross-sectional study

Rukhsana Ahmed, Neeru Singh, Feiko O ter Kuile, Praveen K Bharti, Pushpendra P Singh, Meghna Desai, Venkatachalam Udhayakumar, Dianne J Terlouw

Open Access Methodology

Limit of blank and limit of detection of Plasmodium falciparum thick blood smear microscopy in a routine setting in Central Africa

Fanny Joanny, Sascha JZ Löhr, Thomas Engleitner, Bertrand Lell, Benjamin Mordmüller

Open Access Methodology

Standardization of blood smears prepared in transparent acetate: an alternative method for the microscopic diagnosis of malaria

Marcia BC Mello, Francisco C Luz, Fabio A Leal-Santos, Eduardo R Alves Jr, Thamires M Gasquez, Cor JF Fontes

Open Access Research

Using infective mosquitoes to challenge monkeys with Plasmodium knowlesi in malaria vaccine studies

Jittawadee R Murphy, Walter R Weiss, David Fryauff, Megan Dowler, Tatyana Savransky, Cristina Stoyanov, Olga Muratova, Lynn Lambert, Sachy Orr-Gonzalez, Katie Lynn Zeleski, Jessica Hinderer, Michael P Fay, Gyan Joshi, Robert W Gwadz, Thomas L Richie, Eileen Franke Villasante, Jason H Richardson, Patrick E Duffy, Jingyang Chen

Open Access Research

Spatiotemporal clusters of malaria cases at village level, northwest Ethiopia

Kassahun Alemu, Alemayehu Worku, Yemane Berhane, Abera Kumie

Open Access Research

Molecular identification of the chitinase genes in Plasmodium relictum

Luz Garcia-Longoria, Olof Hellgren, Staffan Bensch

Open Access Research

The ears of the African elephant: unexpected high seroprevalence of Plasmodium ovale and Plasmodium malariae in healthy populations in Western Africa

Cécile Doderer-Lang, Pascal S Atchade, Lydia Meckert, Elodie Haar, Sylvie Perrotey, Denis Filisetti, Ahmed Aboubacar, Alexander W Pfaff, Julie Brunet, Nicodème W Chabi, Casimir D Akpovi, Ludovic Anani, André Bigot, Ambaliou Sanni, Ermanno Candolfi

Open Access Research

Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case–control study

Tobias O Apinjoh, Judith K Anchang-Kimbi, Clarisse Njua-Yafi, André N Ngwai, Regina N Mugri, Taane G Clark, Kirk A Rockett, Dominic P Kwiatkowski, Eric A Achidi

Open Access Research

Progress in mosquito net coverage in Papua New Guinea

Manuel W Hetzel, Adnan AK Choudhury, Justin Pulford, Yangta Ura, Maxine Whittaker, Peter M Siba, Ivo Mueller

Open Access Research

Remotely-sensed, nocturnal, dew point correlates with malaria transmission in Southern Province, Zambia: a time-series study

David Nygren, Cristina Stoyanov, Clemens Lewold, Fredrik Månsson, John Miller, Aniset Kamanga, Clive J Shiff

Open Access Research

Malaria control in Nepal 1963–2012: challenges on the path towards elimination

Meghnath Dhimal, Bodo Ahrens, Ulrich Kuch

Open Access Research

Drugs use pattern for uncomplicated malaria in medicine retail outlets in Enugu urban, southeast Nigeria: implications for malaria treatment policy

Charles C Ezenduka, Brian O Ogbonna, Obinna I Ekwunife, Mathew J Okonta, Charles O Esimone

Open Access Research

Patterns of malaria indices across three consecutive seasons in children in a highly endemic area of West Africa: a three times-repeated cross-sectional study

Denis-Luc Ardiet, Bertrand Graz, Thomas Szeless, Anne Mauris, Jacques Falquet, Ogobara K Doumbo, Amagana Dolo, Ousmane Guindo, Mahamadou S Sissoko, Moussa Konaré, Sandrine Motamed, André C Rougemont

Open Access Case study

Institutional evolution of a community-based programme for malaria control through larval source management in Dar es Salaam, United Republic of Tanzania

Prosper P Chaki, Khadija Kannady, Deo Mtasiwa, Marcel Tanner, Hassan Mshinda, Ann H Kelly, Gerry F Killeen

Open Access Research

Success or failure of critical steps in community case management of malaria with rapid diagnostic tests: a systematic review

Esmée Ruizendaal, Susan Dierickx, Koen Peeters Grietens, Henk DFH Schallig, Franco Pagnoni, Petra F Mens

Open Access Research

“We have become doctors for ourselves”: motives for malaria self-care among adults in southeastern Tanzania

Emmy Metta, Hinke Haisma, Flora Kessy, Inge Hutter, Ajay Bailey

Open Access Research

Testing a multi-malaria-model ensemble against 30 years of data in the Kenyan highlands

Daniel Ruiz, Cyrille Brun, Stephen J Connor, Judith A Omumbo, Bradfield Lyon, Madeleine C Thomson

Open Access Research

Use of proscribed chloroquine is associated with an increased risk of pfcrt T76 mutation in some parts of Ghana

Kwame K Asare, Johnson N Boampong, Richmond Afoakwah, Elvis O Ameyaw, Rakesh Sehgal, Neils B Quashie

Open Access Research

Self-medication with anti-malarials is a common practice in rural communities of Kilosa district in Tanzania despite the reported decline of malaria

Beatrice Chipwaza, Joseph P Mugasa, Iddy Mayumana, Mbaraka Amuri, Christina Makungu, Paul S Gwakisa

Open Access Research

Incidence of malaria-related fever and morbidity due to Plasmodium falciparum among HIV1-infected pregnant women: a prospective cohort study in South Benin

Alexandre Duvignaud, Lise Denoeud-Ndam, Jocelyn Akakpo, Komlan V Agossou, Aldric Afangnihoun, Didier G Komongui, Félix Atadokpédé, Lucien Dossou-Gbété, Pierre-Marie Girard, Djimon-Marcel Zannou, Michel Cot

Open Access Research

Trends in drug resistance codons in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Kenyan parasites from 2008 to 2012

Dennis W Juma, Angela A Omondi, Luiser Ingasia, Benjamin Opot, Agnes Cheruiyot, Redemptah Yeda, Charles Okudo, Jelagat Cheruiyot, Peninnah Muiruri, Bidii Ngalah, Lorna J Chebon, Fredrick Eyase, Jacob Johnson, Wallace D Bulimo, Hoseah M Akala, Ben Andagalu, Edwin Kamau

Open Access Research

Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum

Vicky M Avery, Sridevi Bashyam, Jeremy N Burrows, Sandra Duffy, George Papadatos, Shyni Puthukkuti, Yuvaraj Sambandan, Shivendra Singh, Thomas Spangenberg, David Waterson, Paul Willis

Open Access Research

Genetic diversity and population structure of Plasmodium vivax in Central China

Yaobao Liu, Sarah Auburn, Jun Cao, Hidayat Trimarsanto, Huayun Zhou, Karen-Ann Gray, Taane G Clark, Ric N Price, Qin Cheng, Rui Huang, Qi Gao

Open Access Research

Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania

Reginald A Kavishe, Petro Paulo, Robert D Kaaya, Akili Kalinga, Marco van Zwetselaar, Jaffu Chilongola, Cally Roper, Michael Alifrangis

Open Access Research

Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes

Kazutoyo Miura, Erik Jongert, Bingbing Deng, Luwen Zhou, John P Lusingu, Chris J Drakeley, Michael P Fay, Carole A Long, Johan Vekemans

Open Access Research

A comparison of five malaria transmission models: benchmark tests and implications for disease control

Dorothy I Wallace, Ben S Southworth, Xun Shi, Jonathan W Chipman, Andrew K Githeko

Open Access Research

Comparative performance of aldolase and lactate dehydrogenase rapid diagnostic tests in Plasmodium vivax detection

Emmanuel E Dzakah, Keren Kang, Chao Ni, Shixing Tang, Jihua Wang, Jufang Wang

Open Access Research

A phase III trial to evaluate the efficacy, fabric integrity and community acceptance of Netprotect® using a recommended long-lasting insecticidal net as positive control

Karel Van Roey, Siv Sovannaroth, Tho Sochantha, Mao Srey Touch, Olivier Pigeon, Vincent Sluydts, Lies Durnez, Marc Coosemans

Open Access Research

Development and optimization of the Suna trap as a tool for mosquito monitoring and control

Alexandra Hiscox, Bruno Otieno, Anthony Kibet, Collins K Mweresa, Philemon Omusula, Martin Geier, Andreas Rose, Wolfgang R Mukabana, Willem Takken

Open Access Methodology

Performance of coumarin-derived dendrimer-based fluorescence-linked immunosorbent assay (FLISA) to detect malaria antigen

Seon-Ju Yeo, Dinh Thi Huong, Jin-Hee Han, Jung-Yeon Kim, Won-Ja Lee, Ho-Joon Shin, Eun-Taek Han, Hyun Park

Open Access Research

Malaria outbreaks in China (1990–2013): a systematic review

Guangyu Lu, Shuisen Zhou, Olaf Horstick, Xu Wang, Yali Liu, Olaf Müller

Open Access Research

Thiamin supplementation does not reduce the frequency of adverse events after anti-malarial therapy among patients with falciparum malaria in southern Laos

Mayfong Mayxay, Maniphone Khanthavong, Lorna Cox, Odai Sichanthongthip, Mallika Imwong, Tiengkham Pongvongsa, Bouasy Hongvanthong, Samlane Phompida, Viengxay Vanisaveth, Nicholas J White, Paul N Newton

Open Access Research

Stated preferences for anti-malarial drug characteristics in Zomba, a malaria endemic area of Malawi

Antonieta Medina-Lara, Ruben E Mujica-Mota, Esthery D Kunkwenzu, David G Lalloo

Open Access Research

The development of loop-mediated isothermal amplification targeting alpha-tubulin DNA for the rapid detection of Plasmodium vivax

Sylvatrie-Danne Dinzouna-Boutamba, Hye-Won Yang, So-Young Joo, Sookwan Jeong, Byoung-Kuk Na, Noboru Inoue, Won-Ki Lee, Hyun-Hee Kong, Dong-Il Chung, Youn-Kyoung Goo, Yeonchul Hong

Open Access Research

Effectiveness of post-campaign, door-to-door, hang-up, and communication interventions to increase long-lasting, insecticidal bed net utilization in Togo (2011–2012): a cluster randomized, control trial

Rachelle E Desrochers, Kendra Siekmans, Peter R Berti, Karen Bramhill, Sarah AW Buchan, Guy K Battah, Dodji Gbetoglo, Kokou Vignikin, Alice Sabino

Open Access Research

Glucose-6-phosphate dehydrogenase polymorphisms and susceptibility to mild malaria in Dogon and Fulani, Mali

Bakary Maiga, Amagana Dolo, Susana Campino, Nuno Sepulveda, Patrick Corran, Kirk A Rockett, Marita Troye-Blomberg, Ogobara K Doumbo, Taane G Clark

Open Access Research

Submicroscopic malaria infection during pregnancy and the impact of intermittent preventive treatment

Lauren M Cohee, Linda Kalilani-Phiri, Sarah Boudova, Sudhaunshu Joshi, Rabia Mukadam, Karl B Seydel, Patricia Mawindo, Phillip Thesing, Steve Kamiza, Kingsley Makwakwa, Atis Muehlenbachs, Terrie E Taylor, Miriam K Laufer

Open Access Research

Evaluation of community-based systems for the surveillance of day three-positive Plasmodium falciparum cases in Western Cambodia

Jonathan Cox, Lek Dy Soley, Tol Bunkea, Siv Sovannaroth, Kheang Soy Ty, Song Ngak, Steven Bjorge, Pascal Ringwald, Steven Mellor, David Sintasath, Sylvia Meek

Open Access Research

Dihydroisoxazole inhibitors of Anopheles gambiae seminal transglutaminase AgTG3

Binh V Le, Cornelius Klöck, Alexandra Schatz, Jennifer B Nguyen, Evdoxia G Kakani, Flaminia Catteruccia, Chaitan Khosla, Richard HG Baxter

Open Access Research

Eliminating Plasmodium falciparum in Hainan, China: a study on the use of behavioural change communication intervention to promote malaria prevention in mountain worker populations

Chang-hua He, Xi-min Hu, Guang-ze Wang, Wei Zhao, Ding-wei Sun, Yu-chun Li, Chun-xiang Chen, Jian-wei Du, Shan-qing Wang

Open Access Research

DDX39B (BAT1), TNF and IL6 gene polymorphisms and association with clinical outcomes of patients with Plasmodium vivax malaria

Vitor RR Mendonça, Ligia CL Souza, Gabriela C Garcia, Belisa ML Magalhães, Marcus VG Lacerda, Bruno B Andrade, Marilda S Gonçalves, Manoel Barral-Netto

Open Access Research

Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study

Qigui Li, Shon Remich, Scott R Miller, Bernhards Ogutu, Walter Otieno, Victor Melendez, Paktiya Teja-Isavadharm, Peter J Weina, Mark R Hickman, Bryan Smith, Mark Polhemus

Open Access Research

Management of febrile children under five years in hospitals and health centres of rural Ghana

Jayne Webster, Frank Baiden, Justina Bawah, Jane Bruce, Mathilda Tivura, Rupert Delmini, Seeba Amenga-Etego, Daniel Chandramohan, Seth Owusu-Agyei

Open Access Review

Pregnancy-associated malaria and malaria in infants: an old problem with present consequences

Violeta Moya-Alvarez, Rosa Abellana, Michel Cot

Open Access Review

Magnetic resonance imaging during life: the key to unlock cerebral malaria pathogenesis?

Sanjib Mohanty, Terrie E Taylor, Sam Kampondeni, Mike J Potchen, Premanand Panda, Megharay Majhi, Saroj K Mishra, Samuel C Wassmer

Open Access Research

Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case–control study of African children

Laura K Erdman, Carlene Petes, Ziyue Lu, Aggrey Dhabangi, Charles Musoke, Christine M Cserti-Gazdewich, Chun Geun Lee, Wayne Conrad Liles, Jack A Elias, Kevin C Kain

Open Access Research

Imported malaria in a non-endemic area: the experience of the university of Campinas hospital in the Brazilian Southeast

João C K Dos-Santos, Rodrigo N Angerami, Catarina M S Castiñeiras, Stefanie C P Lopes, Letusa Albrecht, Márcia T Garcia, Carlos E Levy, Maria L Moretti, Marcus V G Lacerda, Fabio T M Costa

Open Access Review

Plasmodium falciparum parasites lacking histidine-rich protein 2 and 3: a review and recommendations for accurate reporting

Qin Cheng, Michelle L Gatton, John Barnwell, Peter Chiodini, James McCarthy, David Bell, Jane Cunningham

Open Access Methodology

Methaemoglobin and COHb in patients with malaria

Thomas Hänscheid, Tom Gresnigt, Sascha Löhr, Arnaud Flamen, Thomas Zoller, José Melo-Cristino, Martin P Grobusch

Open Access Research

Reports of long-lasting insecticidal bed nets catching on fire: a threat to bed net users and to successful malaria control?

Marc Egrot, Roch Houngnihin, Carine Baxerres, Georgia Damien, Armel Djènontin, Fabrice Chandre, Cédric Pennetier, Vincent Corbel, Franck Remoué

Open Access Research

Production and characterization of specific monoclonal antibodies binding the Plasmodium falciparum diagnostic biomarker, histidine-rich protein 2

Chiuan Herng Leow, Martina Jones, Qin Cheng, Stephen Mahler, James McCarthy

Open Access Research

Reduced prevalence of placental malaria in primiparae with blood group O

George Bedu-Addo, Prabhanjan P Gai, Stefanie Meese, Teunis A Eggelte, Kumarasamy Thangaraj, Frank P Mockenhaupt

Open Access Research

Exposure to disinfectants (soap or hydrogen peroxide) increases tolerance to permethrin in Anopheles gambiae populations from the city of Yaoundé, Cameroon

Christophe Antonio-Nkondjio, Marlene Youmsi-Goupeyou, Edmond Kopya, Billy Tene-Fossog, Flobert Njiokou, Carlo Costantini, Parfait Awono-Ambene

Open Access Commentary

The challenge of artemisinin resistance can only be met by eliminating Plasmodium falciparum malaria across the Greater Mekong subregion

Cara Smith Gueye, Gretchen Newby, Jimee Hwang, Allison A Phillips, Maxine Whittaker, John R MacArthur, Roly D Gosling, Richard GA Feachem

Open Access Research

Declining efficacy of artesunate plus sulphadoxine-pyrimethamine in northeastern India

Neelima Mishra, Kamlesh Kaitholia, Bina Srivastava, Naman K Shah, Jai Prakash Narayan, Vas Dev, Sobhan Phookan, Anupkumar R Anvikar, Roma Rana, Ram Suresh Bharti, Gagan Singh Sonal, Akshay Chand Dhariwal, Neena Valecha

Open Access Research

Measurement of parasitological data by quantitative real-time PCR from controlled human malaria infection trials at the Walter Reed Army Institute of Research

Edwin Kamau, Saba Alemayehu, Karla C Feghali, Jack Komisar, Jason Regules, Jessica Cowden, Christian F Ockenhouse

Open Access Research

Towards malaria elimination in Mpumalanga, South Africa: a population-level mathematical modelling approach

Sheetal P Silal, Francesca Little, Karen I Barnes, Lisa J White

Open Access Methodology

Modelling recurrent events: comparison of statistical models with continuous and discontinuous risk intervals on recurrent malaria episodes data

Issaka Sagara, Roch Giorgi, Ogobara K Doumbo, Renaud Piarroux, Jean Gaudart

Open Access Research

Risk factors for UK Plasmodium falciparum cases

Amy Pinsent, Jonathan M Read, Jamie T Griffin, Valerie Smith, Peter W Gething, Azra C Ghani, Geoffrey Pasvol, T Déirdre Hollingsworth

Open Access Research

In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated falciparum malaria in children: a multisite, open-label, two-cohort, clinical trial in Mozambique

Abel Nhama, Quique Bassat, Sónia Enosse, Arsenio Nhacolo, Rosália Mutemba, Eva Carvalho, Eva Naueia, Esperança Sevene, Caterina Guinovart, Marian Warsame, Sergi Sanz, Abdul Mussa, Graça Matsinhe, Pedro Alonso, Armindo Tiago, Eusebio Macete

Open Access Research

Prevalence of pfmdr1 alleles associated with artemether-lumefantrine tolerance/resistance in Maputo before and after the implementation of artemisinin-based combination therapy

Elsa Lobo, Bruno de Sousa, Soraia Rosa, Paula Figueiredo, Lis Lobo, Sara Pateira, Natercia Fernandes, Fatima Nogueira

Open Access Research

Malaria-related knowledge and prevention practices in four neighbourhoods in and around Mumbai, India: a cross-sectional study

Gaurav Dhawan, Nidhin Joseph, Penelope S Pekow, Christine A Rogers, Krishna C Poudel, Maria T Bulzacchelli

Open Access Research

Malaria diagnostic capacity in health facilities in Ethiopia

Tesfay Abreha, Bereket Alemayehu, Yehualashet Tadesse, Sintayehu Gebresillassie, Abebe Tadesse, Leykun Demeke, Fanuel Zewde, Meseret Habtamu, Mekonnen Tadesse, Damtew Yadeta, Dawit Teshome, Addis Mekasha, Kedir Gobena, Henock Bogale, Zenebe Melaku, Richard Reithinger, Hiwot Teka

Open Access Research

Rapid diagnostic test supply chain and consumption study in Cabo Delgado, Mozambique: estimating stock shortages and identifying drivers of stock-outs

Leah Hasselback, Jessica Crawford, Timoteo Chaluco, Sharanya Rajagopal, Wendy Prosser, Noel Watson

Open Access Research

Interaction between rifampicin, amodiaquine and artemether in mice infected with chloroquine resistant Plasmodium berghei

Joseph A Badejo, Oyindamola O Abiodun, Olugbenga Akinola, Christian T Happi, Akintunde Sowunmi, Grace O Gbotosho

Open Access Research

Severity in Plasmodium vivax malaria claiming global vigilance and exploration – a tertiary care centre-based cohort study

Kavitha Saravu, Kumar Rishikesh, Asha Kamath, Ananthakrishna B Shastry

Open Access Research

Factors influencing malaria control policy-making in Kenya, Uganda and Tanzania

Clifford M Mutero, Randall A Kramer, Christopher Paul, Adriane Lesser, Marie Lynn Miranda, Leonard EG Mboera, Rebecca Kiptui, Narcis Kabatereine, Birkinesh Ameneshewa

Open Access Research

A comparative case control study of the determinants of clinical malaria in The Gambia

Joseph Okebe, Julia Mwesigwa, Eugene L Kama, Serign J Ceesay, Fanta Njie, Simon Correa, Kalifa Bojang

Open Access Research

Towards seasonal forecasting of malaria in India

Jonathan M Lauderdale, Cyril Caminade, Andrew E Heath, Anne E Jones, David A MacLeod, Krushna C Gouda, Upadhyayula Suryanarayana Murty, Prashant Goswami, Srinivasa R Mutheneni, Andrew P Morse

Open Access Research

IFN-gamma and TNF associated with severe falciparum malaria infection in Saudi pregnant women

Amre Nasr, Gamal Allam, Osama Hamid, Abdelhamid Al-Ghamdi

Open Access Research

In vitro and in vivo anti-malarial activity of limonoids isolated from the residual seed biomass from Carapa guianensis (andiroba) oil production

Tiago B Pereira, Luiz F Rocha e Silva, Rodrigo CN Amorim, Márcia RS Melo, Rita C Zacardi de Souza, Marcos N Eberlin, Emerson S Lima, Marne C Vasconcellos, Adrian M Pohlit

Open Access Research

High plasma levels of HLA-G are associated with low birth weight and with an increased risk of malaria in infancy

Ibrahim Sadissou, Tania d’Almeida, Gilles Cottrell, Adrian Luty, Irène Krawice-Radanne, Achille Massougbodji, Philippe Moreau, Kabirou Moutairou, André Garcia, Benoit Favier, Nathalie Rouas-Freiss, David Courtin

Open Access Methodology

Comparison of three methods for detection of gametocytes in Melanesian children treated for uncomplicated malaria

Stephan Karl, Moses Laman, Tamarah Koleala, Clemencia Ibam, Bernadine Kasian, Nola N’Drewei, Anna Rosanas-Urgell, Brioni R Moore, Andreea Waltmann, Cristian Koepfli, Peter M Siba, Inoni Betuela, Robert C Woodward, Timothy G St Pierre, Ivo Mueller, Timothy ME Davis

Open Access Research

Detection of antibodies against the CB9 to ICB10 region of merozoite surface protein-1 of Plasmodium vivax among the inhabitants in epidemic areas

Tong-Soo Kim, Youngjoo Sohn, Jung-Yeon Kim, Won-Ja Lee, Byoung-kuk Na, Yoon-Joong Kang, Hyeong-Woo Lee

Open Access Research

Estimates of adherence to treatment of vivax malaria

Eduardo D Almeida, Luiz Carlos S Rodrigues, José Luiz F Vieira

Open Access Research

“You need to take care of it like you take care of your soul”: perceptions and behaviours related to mosquito net damage, care, and repair in Senegal

Dana K Loll, Sara Berthe, Sylvain L Faye, Issa Wone, Bethany Arnold, Hannah Koenker, Joan Schubert, Youssoufa Lo, Julie Thwing, Ousmane Faye, Rachel Weber

Open Access Research

Tumour necrosis factor, interleukin-6 and interleukin-10 are possibly involved in Plasmodium vivax-associated thrombocytopaenia in southern Pakistani population

Afsheen Raza, Muhammad Shahzeb Khan, Najia Karim Ghanchi, Ahmed Raheem, Mohammad A Beg

Open Access Research

Socio-economic determinants of ownership and use of treated bed nets in Nigeria: results from a cross-sectional study in Cross River and Bauchi States in 2011

Morwell Eteng, Steven Mitchell, Lawal Garba, Onebieni Ana, Mohammed Liman, Anne Cockcroft, Neil Andersson

Open Access Research

The effects of genetic manipulation, dieldrin treatment and irradiation on the mating competitiveness of male Anopheles arabiensis in field cages

Hanano Yamada, Marc JB Vreysen, Jeremie RL Gilles, Givemore Munhenga, David D Damiens

Open Access Research

Cost analysis of the development and implementation of a spatial decision support system for malaria elimination in Solomon Islands

Luke Marston, Gerard C Kelly, Erick Hale, Archie CA Clements, Andrew Hodge, Eliana Jimenez-Soto

Open Access Research

Performance of HRP2-based rapid test in children attending the health centre compared to asymptomatic children in the community

Gillon Ilombe, Vivi Maketa, Hypolite Muhindo Mavoko, Raquel Inocêncio da Luz, Pascal Lutumba, Jean-Pierre Van geertruyden

Open Access Research

“We are supposed to take care of it”: a qualitative examination of care and repair behaviour of long-lasting, insecticide-treated nets in Nasarawa State, Nigeria

Gabrielle C Hunter, Leah Scandurra, Angela Acosta, Hannah Koenker, Emmanuel Obi, Rachel Weber

Open Access Research

Proteomic analysis of the Plasmodium male gamete reveals the key role for glycolysis in flagellar motility

Arthur M Talman, Judith H Prieto, Sara Marques, Ceereena Ubaida-Mohien, Mara Lawniczak, Mark N Wass, Tao Xu, Roland Frank, Andrea Ecker, Rebecca S Stanway, Sanjeev Krishna, Michael JE Sternberg, Georges K Christophides, David R Graham, Rhoel R Dinglasan, John R Yates III, Robert E Sinden

Open Access Research

Increasing role of Anopheles funestus and Anopheles arabiensis in malaria transmission in the Kilombero Valley, Tanzania

Dickson W Lwetoijera, Caroline Harris, Samson S Kiware, Stefan Dongus, Gregor J Devine, Philip J McCall, Silas Majambere

Open Access Research

Cytoadherence phenotype of Plasmodium falciparum- infected erythrocytes is associated with specific pfemp-1 expression in parasites from children with cerebral malaria

Talleh Almelli, Nicaise T Ndam, Sem Ezimegnon, Maroufou J Alao, Charles Ahouansou, Gratien Sagbo, Annick Amoussou, Philippe Deloron, Rachida Tahar

Open Access Research

A malaria vaccine candidate based on an epitope of the Plasmodium falciparum RH5 protein

Rosalynn L Ord, Jerri C Caldeira, Marilis Rodriguez, Amy Noe, Bryce Chackerian, David S Peabody, Gabriel Gutierrez, Cheryl A Lobo

Open Access Research

In vitro antiplasmodial activity of cepharanthine

Camille Desgrouas, Charles Chapus, Jérôme Desplans, Christelle Travaille, Aurélie Pascual, Béatrice Baghdikian, Evelyne Ollivier, Daniel Parzy, Nicolas Taudon

Open Access Commentary

Finding connections in the unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: a fact in the Atlantic Forest

Maria Anice Mureb Sallum, Cláudio Tadeu Daniel-Ribeiro, Gabriel Zorello Laporta, Maria de Fátima Ferreira-da-Cruz, Luciana Morganti Ferreira Maselli, Débora Levy, Sérgio Paulo Bydlowski

Open Access Commentary

Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?

Alfredo Mendrone Jr, Crispim Cerutti Jr, José Eduardo Levi, Marcos Boulos, Maria Carmen Arroyo Sanchez, Rosely dos Santos Malafronte, Silvia Maria Di Santi, Vicente Odone Jr

Open Access Research

Micro-encapsulated pirimiphos-methyl shows high insecticidal efficacy and long residual activity against pyrethroid-resistant malaria vectors in central Côte d’Ivoire

Emile S Tchicaya, Christian Nsanzabana, Thomas A Smith, Jennifer Donzé, Maiti Laserna de Hipsl, Yao Tano, Pie Müller, Olivier JT Briët, Jürg Utzinger, Benjamin G Koudou

Open Access Research

Effects of the kdr resistance mutation on the susceptibility of wild Anopheles gambiae populations to Plasmodium falciparum: a hindrance for vector control

Mamadou Ousmane Ndiath, Aurélie Cailleau, Seynabou Mocote Diedhiou, Abdoulaye Gaye, Christian Boudin, Vincent Richard, Jean-François Trape

Open Access Research

Development and validation of climate and ecosystem-based early malaria epidemic prediction models in East Africa

Andrew K Githeko, Laban Ogallo, Martha Lemnge, Michael Okia, Ednah N Ototo

Open Access Review

Plasmodium falciparum malaria and invasive bacterial co-infection in young African children: the dysfunctional spleen hypothesis

Gloria P Gómez-Pérez, Robin van Bruggen, Martin P Grobusch, Carlota Dobaño

Open Access Case report

Severe Plasmodium falciparum infection mimicking acute myocardial infarction

Helmi Sulaiman, Muhammad Dzafir Ismail, Maisarah Jalalonmuhali, Nadia Atiya, Sasheela Ponnampalavanar

Open Access Research

Monitoring long-lasting insecticidal net (LLIN) durability to validate net serviceable life assumptions, in Rwanda

Emmanuel Hakizimana, Beatus Cyubahiro, Alphonse Rukundo, Allan Kabayiza, Alphonse Mutabazi, Raymond Beach, Roopal Patel, Jon E Tongren, Corine Karema

Open Access Research

Molecular surveillance of pvdhfr, pvdhps, and pvmdr-1 mutations in Plasmodium vivax isolates from Yunnan and Anhui provinces of China

Bo Huang, Shiguang Huang, Xin-zhuan Su, Xinxin Tong, Junping Yan, Hongbin Li, Fangli Lu

Open Access Research

Prevalence of asymptomatic malaria and bed net ownership and use in Bhutan, 2013: a country earmarked for malaria elimination

Kinley Wangdi, Michelle L Gatton, Gerard C Kelly, Archie CA Clements

Open Access Review

Recent progress in the development of anti-malarial quinolones

Richard M Beteck, Frans J Smit, Richard K Haynes, David D N’Da

Open Access Research

Environmental temperatures significantly change the impact of insecticides measured using WHOPES protocols

Katey D Glunt, Krijn P Paaijmans, Andrew F Read, Matthew B Thomas

Open Access Research

Evaluation of universal coverage of insecticide-treated nets in western Kenya: field surveys

Guofa Zhou, Jessica S Li, Ednah N Ototo, Harrysone E Atieli, Andrew K Githeko, Guiyun Yan

Open Access Research

Malaria treatment policy change in Uganda: what role did evidence play?

Juliet Nabyonga-Orem, Freddie Ssengooba, Jean Macq, Bart Criel

Open Access Research

Loss of Toll-like receptor 7 alters cytokine production and protects against experimental cerebral malaria

Alyssa Baccarella, Brian W Huang, Mary F Fontana, Charles C Kim

Open Access Research

PCR/RFLP-Based Analysis of Genetically Distinct Plasmodium vivax Population of Pvmsp-3α and Pvmsp-3β genes in Pakistan

Shahid Niaz Khan, Asif Khan, Sanaullah Khan, Sultan Ayaz, Sobia Attaullah, Jabbar Khan, Muhammad Asim Khan, Ijaz Ali, Abdul Haleem Shah

Open Access Methodology

Comparative assessment of diverse strategies for malaria vector population control based on measured rates at which mosquitoes utilize targeted resource subsets

Gerry F Killeen, Samson S Kiware, Aklilu Seyoum, John E Gimnig, George F Corliss, Jennifer Stevenson, Christopher J Drakeley, Nakul Chitnis

Open Access Research

Insecticide-treated nets ownership and utilization among under-five children following the 2010 mass distribution in Burkina Faso

Souleymane Diabaté, Thomas Druetz, Emmanuel Bonnet, Seni Kouanda, Valéry Ridde, Slim Haddad

Open Access Research

Impairment of executive function in Kenyan children exposed to severe falciparum malaria with neurological involvement

Symon M Kariuki, Amina Abubakar, Charles RJC Newton, Michael Kihara

Open Access Research

Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity

Sanna R Rijpma, Jeroen JMW van den Heuvel, Maarten van der Velden, Robert W Sauerwein, Frans GM Russel, Jan B Koenderink

Open Access Research

Age-specific malaria seroprevalence rates: a cross-sectional analysis of malaria transmission in the Ouest and Sud-Est departments of Haiti

Michael E von Fricken, Thomas A Weppelmann, Brandon Lam, Will T Eaton, Laura Schick, Roseline Masse, Madsen V Beau De Rochars, Alexandre Existe, Joseph Larkin III, Bernard A Okech

Open Access Research

Delayed anemia assessment in patients treated with oral artemisinin derivatives for uncomplicated malaria: a pooled analysis of clinical trials data from Mali

Issaka Sagara, Renaud Piarroux, Abdoulaye Djimde, Roch Giorgi, Kassoum Kayentao, Ogobara K Doumbo, Jean Gaudart

Open Access Research

A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria

George O Adjei, Bamenla Q Goka, Christabel C Enweronu-Laryea, Onike P Rodrigues, Lorna Renner, Abdul M Sulley, Michael Alifrangis, Insaf Khalil, Jorgen A Kurtzhals

Open Access Research

Novel approaches to risk stratification to support malaria elimination: an example from Cambodia

Jonathan Cox, Siv Sovannaroth, Lek Dy Soley, Pengby Ngor, Steven Mellor, Arantxa Roca-Feltrer

Open Access Research

Detection of Plasmodium knowlesi DNA in the urine and faeces of a Japanese macaque (Macaca fuscata) over the course of an experimentally induced infection

Satoru Kawai, Megumi Sato, Naoko Kato-Hayashi, Hisashi Kishi, Michael A Huffman, Yoshimasa Maeno, Richard Culleton, Shusuke Nakazawa

Open Access Research

Prevention measures and socio-economic development result in a decrease in malaria in Hainan, China

Shan-Qing Wang, Yu-Chun Li, Zhi-Ming Zhang, Guang-Ze Wang, Xi-Min Hu, Whitney A Qualls, Rui-De Xue

Open Access Research

Therapeutic efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in North-Eastern Tanzania

Alex Shayo, Celine I Mandara, Francis Shahada, Joram Buza, Martha M Lemnge, Deus S Ishengoma

Open Access Research

Analysis of polymorphisms in Plasmodium falciparum genes related to drug resistance: a survey over four decades under different treatment policies in Brazil

Juliana Inoue, Dinora Lopes, Virgílio do Rosário, Marta Machado, Angélica D Hristov, Giselle FMC Lima, Maria J Costa-Nascimento, Aluísio C Segurado, Silvia M Di Santi

Open Access Research

Monitoring Plasmodium vivax chloroquine sensitivity along China-Myanmar border of Yunnan Province, China during 2008–2013

Hui Liu, Heng-lin Yang, Lin-hua Tang, Xing-liang Li, Fang Huang, Jia-zhi Wang, Chun-fu Li, Heng-ye Wang, Ren-hua Nie, Xiang-rui Guo, Ying-xue Lin, Mei Li, Jian-Wei Xu

Open Access Research

Insecticide-treated net wall hangings for malaria vector control: an experimental hut study in north-eastern Tanzania

Corine Ngufor, Patrick Tungu, Robert Malima, Matthew Kirby, William Kisinza, Mark Rowland

Open Access Methodology

Label-free microfluidic enrichment of ring-stage Plasmodium falciparum-infected red blood cells using non-inertial hydrodynamic lift

Thomas M Geislinger, Sherwin Chan, Kirsten Moll, Achim Wixforth, Mats Wahlgren, Thomas Franke

Open Access Research

Stable malaria incidence despite scaling up control strategies in a malaria vaccine-testing site in Mali

Drissa Coulibaly, Mark A Travassos, Abdoulaye K Kone, Youssouf Tolo, Matthew B Laurens, Karim Traore, Issa Diarra, Amadou Niangaly, Modibo Daou, Ahmadou Dembele, Mody Sissoko, Bouréima Guindo, Raymond Douyon, Aldiouma Guindo, Bourema Kouriba, Mahamadou S Sissoko, Issaka Sagara, Christopher V Plowe, Ogobara K Doumbo, Mahamadou A Thera

Open Access Methodology

Development and application of an AllGlo probe-based qPCR assay for detecting knockdown resistance (kdr) mutations in Anopheles sinensis

Liang Bai, Guo-ding Zhu, Hua-yun Zhou, Jian-xia Tang, Ju-lin Li, Sui Xu, Mei-hua Zhang, Li-nong Yao, Guang-quan Huang, Yong-bin Wang, Hong-wei Zhang, Si-bao Wang, Jun Cao, Qi Gao

Open Access Research

Transcriptome sequencing and analysis of Plasmodium gallinaceum reveals polymorphisms and selection on the apical membrane antigen-1

Elvin J Lauron, Khouanchy S Oakgrove, Lisa A Tell, Kevin Biskar, Scott W Roy, Ravinder NM Sehgal

Open Access Research

Association between malaria control and paediatric blood transfusions in rural Zambia: an interrupted time-series analysis

Alison B Comfort, Janneke H van Dijk, Sungano Mharakurwa, Kathryn Stillman, Benjamin Johns, Payal Hathi, Sonali Korde, Allen S Craig, Nancy Nachbar, Yann Derriennic, Rose Gabert, Philip E Thuma

Open Access Research

Spatial clustering and risk factors of malaria infections in Ratanakiri Province, Cambodia

Vincent Sluydts, Somony Heng, Marc Coosemans, Karel Van Roey, Charlotte Gryseels, Lydie Canier, Saorin Kim, Nimol Khim, Sovannaroth Siv, Vanna Mean, Sambunny Uk, Koen Peeters Grietens, Sochantha Tho, Didier Menard, Lies Durnez

Open Access Research

Low genetic diversity in the locus encoding the Plasmodium vivax P41 protein in Colombia’s parasite population

Johanna Forero-Rodríguez, Diego Garzón-Ospina, Manuel A Patarroyo

Open Access Research

The diminishing returns of atovaquone-proguanil for elimination of Plasmodium falciparum malaria: modelling mass drug administration and treatment

Richard J Maude, Chea Nguon, Arjen M Dondorp, Lisa J White, Nicholas J White

Open Access Research

Prevalence and spectrum of illness among hospitalized adults with malaria in Blantyre, Malawi

Dalitso Segula, Anne P Frosch, Miguel SanJoaquin, Dalitso Taulo, Jacek Skarbinski, Don P Mathanga, Theresa J Allain, Malcolm Molyneux, Miriam K Laufer, Robert S Heyderman

Open Access Research

Antibody response against three Plasmodium falciparum merozoite antigens in Mamuju District, West Sulawesi Province, Indonesia

Nurhayana Sennang, Stephen Rogerson, Sitti Wahyuni, Irawan Yusuf, Din Syafruddin

Open Access Research

Mosquito magnet® liberty plus trap baited with octenol confirmed best candidate for Anopheles surveillance and proved promising in predicting risk of malaria transmission in French Guiana

Samuel B Vezenegho, Antoine Adde, Pascal Gaborit, Romuald Carinci, Jean Issaly, Vincent Pommier de Santi, Isabelle Dusfour, Sébastien Briolant, Romain Girod

Open Access Research

Changing epidemiology of malaria in Sabah, Malaysia: increasing incidence of Plasmodium knowlesi

Timothy William, Jenarun Jelip, Jayaram Menon, Fread Anderios, Rashidah Mohammad, Tajul A Awang Mohammad, Matthew J Grigg, Tsin W Yeo, Nicholas M Anstey, Bridget E Barber

Open Access Methodology

Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

Wathsala Wijayalath, Sai Majji, Eileen F Villasante, Teodor D Brumeanu, Thomas L Richie, Sofia Casares

Open Access Methodology

A nested real-time PCR assay for the quantification of Plasmodium falciparum DNA extracted from dried blood spots

Tuan M Tran, Amirali Aghili, Shanping Li, Aissata Ongoiba, Kassoum Kayentao, Safiatou Doumbo, Boubacar Traore, Peter D Crompton

Open Access Research

Fishing with bed nets on Lake Tanganyika: a randomized survey

Kate A McLean, Aisha Byanaku, Augustine Kubikonse, Vincent Tshowe, Said Katensi, Amy G Lehman

Open Access Research

Global and local genetic diversity at two microsatellite loci in Plasmodium vivax parasites from Asia, Africa and South America

Mette L Schousboe, Samir Ranjitkar, Rupika S Rajakaruna, Priyanie H Amerasinghe, Flemming Konradsen, Francisco Morales, Rosalynn Ord, Richard Pearce, Toby Leslie, Mark Rowland, Nahla Gadalla, Ib C Bygbjerg, Michael Alifrangis, Cally Roper

Open Access Research

Plasmodium prevalence and artemisinin-resistant falciparum malaria in Preah Vihear Province, Cambodia: a cross-sectional population-based study

Philippe Bosman, Jorgen Stassijns, Fabienne Nackers, Lydie Canier, Nimol Kim, Saorin Khim, Sweet C Alipon, Meng Chuor Char, Nguon Chea, Lek Dysoley, Rafael Van den Bergh, William Etienne, Martin De Smet, Didier Ménard, Jean-Marie Kindermans

Open Access Case report

Severe delayed autoimmune haemolytic anaemia following artesunate administration in severe malaria: a case report

Loic Raffray, Marie-Catherine Receveur, Mathilde Beguet, Pierre Lauroua, Thierry Pistone, Denis Malvy

Open Access Research

The performance evaluation of a urine malaria test (UMT) kit for the diagnosis of malaria in individuals with fever in south-east Nigeria: cross-sectional analytical study

Tagbo Oguonu, Elvis Shu, Bertilla U Ezeonwu, Bao Lige, Anne Derrick, Rich E Umeh, Eddy Agbo

Open Access Research

A descriptive study of 16 severe Plasmodium vivax cases from three municipalities of Colombia between 2009 and 2013

Anthony T O’Brien, Jesica F Ramírez, Sandra P Martínez

Open Access Research

Enantiomerically pure amino-alcohol quinolines: in vitro anti-malarial activity in combination with dihydroartemisinin, cytotoxicity and in vivo efficacy in a Plasmodium berghei mouse model

Catherine Mullié, Nicolas Taudon, Camille Degrouas, Alexia Jonet, Aurélie Pascual, Patrice Agnamey, Pascal Sonnet

Open Access Research

Anti-relapse activity of mirincamycin in the Plasmodium cynomolgi sporozoite-infected Rhesus monkey model

Susan Fracisco, Paktiya Teja-isavadharm, Montip Gettayacamin, Jonathan Berman, Qigui Li, Victor Melendez, David Saunders, Lisa Xie, Colin Ohrt

Open Access Research

Clinical malaria case definition and malaria attributable fraction in the highlands of western Kenya

Yaw A Afrane, Guofa Zhou, Andrew K Githeko, Guiyun Yan

Open Access Research

Stability profiling of anti-malarial drug piperaquine phosphate and impurities by HPLC-UV, TOF-MS, ESI-MS and NMR

Fang Yan, Jie Liu, Xuefang Zeng, Yuan Zhang, Taijun Hang

Open Access Research

Genetic mutations in pfcrt and pfmdr1 at the time of artemisinin combination therapy introduction in South Pacific islands of Vanuatu and Solomon Islands

Karryn J Gresty, Karen-Ann Gray, Albino Bobogare, George Taleo, Jeffrey Hii, Lyndes Wini, Qin Cheng, Norman C Waters

Open Access Research

Nationwide assessment of insecticide susceptibility in Anopheles gambiae populations from Zimbabwe

Nzira Lukwa, Shadreck Sande, Aramu Makuwaza, Tonderai Chiwade, Martin Netsa, Kwame Asamoa, Gonzalo Vazquez-Prokopec, Richard Reithinger, Jacob Williams

Open Access Research

Malaria parasite detection increases during pregnancy in wild chimpanzees

Hélène M De Nys, Sébastien Calvignac-Spencer, Christophe Boesch, Pierre Dorny, Roman M Wittig, Roger Mundry, Fabian H Leendertz

Open Access Research

Efficacy of intravenous methylene blue, intravenous artesunate, and their combination in preclinical models of malaria

Colin Ohrt, Qigui Li, Nicanor Obaldia, Rawiwan Im-erbsin, Lisa Xie, Jonathan Berman

Open Access Methodology

High-throughput tri-colour flow cytometry technique to assess Plasmodium falciparum parasitaemia in bioassays

Regis W Tiendrebeogo, Bright Adu, Susheel K Singh, Daniel Dodoo, Morten H Dziegiel, Benjamin Mordmüller, Issa Nébié, Sodiomon B Sirima, Michael Christiansen, Michael Theisen

Open Access Research

Cost of treating inpatient falciparum malaria on the Thai-Myanmar border

Shwe Sin Kyaw, Tom Drake, Ronatrai Ruangveerayuth, Wirongrong Chierakul, Nicholas J White, Paul N Newton, Yoel Lubell

Open Access Research

Comparative analysis of IgG responses to Plasmodium falciparum MSP1p19 and PF13-DBL1α1 using ELISA and a magnetic bead-based duplex assay (MAGPIX®-Luminex) in a Senegalese meso-endemic community

Ronald Perraut, Vincent Richard, Marie-Louise Varela, Jean-François Trape, Micheline Guillotte, Adama Tall, Aissatou Toure, Cheikh Sokhna, Inès Vigan-Womas, Odile Mercereau-Puijalon

Open Access Research

Evaluation of ivermectin mass drug administration for malaria transmission control across different West African environments

Haoues Alout, Benjamin J Krajacich, Jacob I Meyers, Nathan D Grubaugh, Doug E Brackney, Kevin C Kobylinski, Joseph W Diclaro II, Fatorma K Bolay, Lawrence S Fakoli, Abdoulaye Diabaté, Roch K Dabiré, Roland W Bougma, Brian D Foy

Open Access Research

Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations

Karol J Marwa, Theresa Schmidt, Maria Sjögren, Omary MS Minzi, Erasmus Kamugisha, Göte Swedberg

Open Access Case report

Severe Plasmodium knowlesi infection with multi-organ failure imported to Germany from Thailand/Myanmar

Michael Seilmaier, Wulf Hartmann, Marcus Beissner, Thomas Fenzl, Cathrine Haller, Wolfgang Guggemos, Jan Hesse, Adinda Harle, Gisela Bretzel, Stefan Sack, Clemens Wendtner, Thomas Löscher, Nicole Berens-Riha

Open Access Review

Primaquine: the risks and the benefits

Elizabeth A Ashley, Judith Recht, Nicholas J White

Open Access Research

Subclass responses and their half-lives for antibodies against EBA175 and PfRh2 in naturally acquired immunity against Plasmodium falciparum malaria

Hodan Ahmed Ismail, Muyideen K Tijani, Christine Langer, Linda Reiling, Michael T White, James G Beeson, Mats Wahlgren, Roseangela Nwuba, Kristina EM Persson

Open Access Research

Evaluation of a universal coverage bed net distribution campaign in four districts in Sofala Province, Mozambique

Mateusz M Plucinski, Silvia Chicuecue, Eusébio Macete, James Colborn, Steven S Yoon, S Patrick Kachur, Pedro Aide, Pedro Alonso, Caterina Guinovart, Juliette Morgan

Open Access Research

The epidemiology of Plasmodium vivax and Plasmodium falciparum malaria in China, 2004–2012: from intensified control to elimination

Qian Zhang, Shengjie Lai, Canjun Zheng, Honglong Zhang, Sheng Zhou, Wenbiao Hu, Archie CA Clements, Xiao-Nong Zhou, Weizhong Yang, Simon I Hay, Hongjie Yu, Zhongjie Li

Open Access Research

Plasmodium berghei circumsporozoite protein encapsulated in oligomannose-coated liposomes confers protection against sporozoite infection in mice

Mohamad Alaa Terkawi, Yasuhiro Kuroda, Shinya Fukumoto, Sachi Tanaka, Naoya Kojima, Yoshifumi Nishikawa

Open Access Research

An agent-based model of the population dynamics of Anopheles gambiae

SM Niaz Arifin, Ying Zhou, Gregory J Davis, James E Gentile, Gregory R Madey, Frank H Collins

Open Access Research

First report of an exophilic Anopheles arabiensis population in Bissau City, Guinea-Bissau: recent introduction or sampling bias?

Vasco Gordicho, José L Vicente, Carla A Sousa, Beniamino Caputo, Marco Pombi, João Dinis, Gonçalo Seixas, Katinka Palsson, David Weetman, Amabélia Rodrigues, Alessandra della Torre, João Pinto

Open Access Research

Mutations in Plasmodium falciparum K13 propeller gene from Bangladesh (2009–2013)

Abu Naser Mohon, Mohammad Shafiul Alam, Abebe Genetu Bayih, Asongna Folefoc, Dea Shahinas, Rashidul Haque, Dylan R Pillai

Open Access Research

The acceptability of intermittent screening and treatment versus intermittent preventive treatment during pregnancy: results from a qualitative study in Northern Ghana

Christopher Pell, Arantza Meñaca, Samuel Chatio, Abraham Hodgson, Harry Tagbor, Robert Pool

Open Access Research

Net use, care and repair practices following a universal distribution campaign in Mali

Lori Leonard, Samba Diop, Seydou Doumbia, Aboubacar Sadou, Jules Mihigo, Hannah Koenker, Sara Berthe, April Monroe, Kathryn Bertram, Rachel Weber

Open Access Research

In vitro growth of Plasmodium falciparum in neonatal blood

Ulrich Sauerzopf, Yabo J Honkpehedji, Ayôla A Adgenika, Elianne N Feugap, Ghyslain Mombo Ngoma, Jean-Rodolphe Mackanga, Felix Lötsch, Marguerite M Loembe, Peter G Kremsner, Benjamin Mordmüller, Michael Ramharter

Open Access Research

High-resolution melting analysis reveals low Plasmodium parasitaemia infections among microscopically negative febrile patients in western Kenya

Purity N Kipanga, David Omondi, Paul O Mireji, Patrick Sawa, Daniel K Masiga, Jandouwe Villinger

Open Access Research

Transmission patterns of Plasmodium falciparum by Anopheles gambiae in Benin

Virgile Gnanguenon, Renaud Govoetchan, Fiacre R Agossa, Razaki Ossè, Frédéric Oke-Agbo, Roseric Azondekon, Arthur Sovi, Roseline Attolou, Kefilath Badirou, Filémon T Tokponnon, Gil G Padonou, Martin C Akogbeto

Open Access Research

Are topical insect repellents effective against malaria in endemic populations? A systematic review and meta-analysis

Anne L Wilson, Vanessa Chen-Hussey, James G Logan, Steve W Lindsay

Open Access Research

Impact of a training course on the quality of malaria diagnosis by microscopy in Angola

Sofia Moura, Cláudia Fançony, Clara Mirante, Marcela Neves, Luís Bernardino, Filomeno Fortes, Maria do Rosário Sambo, Miguel Brito

Open Access Research

Trends in malaria admissions at the Mbakong Health Centre of the North West Region of Cameroon: a retrospective study

Ignatius C Ndong, Mari van Reenen, Daniel A Boakye, Wilfred F Mbacham, Anne F Grobler

Open Access Research

Glucose-6-phosphate dehydrogenase deficiency among malaria suspects attending Gambella hospital, southwest Ethiopia

Arega Tsegaye, Lemu Golassa, Hassen Mamo, Berhanu Erko

Open Access Research

Open-label, randomized, non-inferiority clinical trial of artesunate-amodiaquine versus artemether-lumefantrine fixed-dose combinations in children and adults with uncomplicated falciparum malaria in Côte d'Ivoire

Offianan A Toure, Serge B Assi, Tiacoh L N’Guessan, Gbessi E Adji, Aristide B Ako, Marie J Brou, Marie F Ehouman, Laeticia A Gnamien, M’Lanhoro AA Coulibaly, Baba Coulibaly, Sylvain Beourou, Issiaka Bassinka, Adama Soumahoro, Florence Kadjo, Mea A Tano

Open Access Case report

First imported relapse case of Plasmodium vivax malaria and analysis of its origin by CSP sequencing in Henan Province, China

Ying Liu, Hong-wei Zhang, Rui-min Zhou, Cheng-yun Yang, Dan Qian, Yu-ling Zhao, Bian-li Xu

Open Access Research

Identifying malaria hotspots in Keur Soce health and demographic surveillance site in context of low transmission

Mansour Ndiath, Babacar Faye, Badara Cisse, Jean Louis Ndiaye, Jules François Gomis, Anta Tal Dia, Oumar Gaye

Open Access Research

Anti-malarial activity of a polyherbal product (Nefang) during early and established Plasmodium infection in rodent models

Protus Arrey Tarkang, Faith A Okalebo, Lawrence S Ayong, Gabriel A Agbor, Anastasia N Guantai

Open Access Research

Characterization of the Anopheles gambiae octopamine receptor and discovery of potential agonists and antagonists using a combined computational-experimental approach

Kevin W Kastner, Douglas A Shoue, Guillermina L Estiu, Julia Wolford, Megan F Fuerst, Lowell D Markley, Jesús A Izaguirre, Mary Ann McDowell

Open Access Research

Patterns and predictors of malaria care-seeking, diagnostic testing, and artemisinin-based combination therapy for children under five with fever in Northern Nigeria: a cross-sectional study

Kathryn R Millar, Jennifer McCutcheon, Eugenie H Coakley, William Brieger, Mohammed A Ibrahim, Zainab Mohammed, Amos Bassi, William Sambisa

Open Access Research

Artemisinin resistance – modelling the potential human and economic costs

Yoel Lubell, Arjen Dondorp, Philippe J Guérin, Tom Drake, Sylvia Meek, Elizabeth Ashley, Nicholas PJ Day, Nicholas J White, Lisa J White

Open Access Research

A heavy legacy: offspring of malaria-infected mosquitoes show reduced disease resistance

Amélie Vantaux, Kounbobr Roch Dabiré, Anna Cohuet, Thierry Lefèvre

Open Access Research

The independent effect of living in malaria hotspots on future malaria infection: an observational study from Misungwi, Tanzania

Jacklin F Mosha, Hugh JW Sturrock, Joelle M Brown, Ramadhani Hashim, Gibson Kibiki, Daniel Chandramohan, Roland D Gosling

Open Access Research

Genetic polymorphism and amino acid sequence variation in Plasmodium falciparum GLURP R2 repeat region in Assam, India, at an interval of five years

Dinesh Kumar, Sunil Dhiman, Bipul Rabha, Diganta Goswami, Manab Deka, Lokendra Singh, Indra Baruah, Vijay Veer

Open Access Methodology

A reliable and rapid method for molecular detection of malarial parasites using microwave irradiation and loop mediated isothermal amplification

Julia R Port, Christian Nguetse, Selorme Adukpo, Thirumalaisamy P Velavan

Open Access Research

Spatio-temporal distribution of malaria and its association with climatic factors and vector-control interventions in two high-risk districts of Nepal

Meghnath Dhimal, Robert B O’Hara, Ramchandra Karki, Garib D Thakur, Ulrich Kuch, Bodo Ahrens

Open Access Research

Mating competitiveness of sterile male Anopheles coluzzii in large cages

Hamidou Maïga, David Damiens, Abdoulaye Niang, Simon P Sawadogo, Omnia Fatherhaman, Rosemary S Lees, Olivier Roux, Roch K Dabiré, Georges A Ouédraogo, Fréderic Tripet, Abdoulaye Diabaté, Jeremie RL Gilles

Open Access Research

What happens to lost nets: a multi-country analysis of reasons for LLIN attrition using 14 household surveys in four countries

Hannah Koenker, Albert Kilian, Celine Zegers de Beyl, Emmanuel O Onyefunafoa, Richmond A Selby, Tarekegn Abeku, Megan Fotheringham, Matthew Lynch

Open Access Research

Serological markers for monitoring historical changes in malaria transmission intensity in a highly endemic region of Western Kenya, 1994–2009

Jacklyn Wong, Mary J Hamel, Chris J Drakeley, Simon Kariuki, Ya Ping Shi, Altaf A Lal, Bernard L Nahlen, Peter B Bloland, Kim A Lindblade, Vincent Were, Kephas Otieno, Peter Otieno, Chris Odero, Laurence Slutsker, John M Vulule, John E Gimnig

Open Access Review

Efficacy and safety of artemisinin combination therapy (ACT) for non-falciparum malaria: a systematic review

Benjamin J Visser, Rosanne W Wieten, Daniëlle Kroon, Ingeborg M Nagel, Sabine Bélard, Michèle van Vugt, Martin P Grobusch

Open Access Research

The outcome of a test-treat package versus routine outpatient care for Ghanaian children with fever: a pragmatic randomized control trial

Emmanuel Ameyaw, Samuel B Nguah, Daniel Ansong, Iain Page, Martine Guillerm, Imelda Bates

Open Access Research

Antiplasmodial activity of chloroquine analogs against chloroquine-resistant parasites, docking studies and mechanisms of drug action

Nicolli B de Souza, Arturene ML Carmo, Adilson D da Silva, Tanos CC França, Antoniana U Krettli

Open Access Research

Mosquito Akirin as a potential antigen for malaria control

Mário da Costa, Renato Pinheiro-Silva, Sandra Antunes, Juan A Moreno-Cid, Ana Custódio, Margarita Villar, Henrique Silveira, José de la Fuente, Ana Domingos

Open Access Research

Operational research on malaria control and elimination: a review of projects published between 2008 and 2013

Shui-sen Zhou, Aafje EC Rietveld, Mar Velarde-Rodriguez, Andrew R Ramsay, Shao-sen Zhang, Xiao-nong Zhou, Richard E Cibulskis

Open Access Research

Feasibility of repellent use in a context of increasing outdoor transmission: a qualitative study in rural Tanzania

Onyango Sangoro, Ann H Kelly, Sarah Mtali, Sarah J Moore

Open Access Research

The effect of timing of iron supplementation on iron absorption and haemoglobin in post-malaria anaemia: a longitudinal stable isotope study in Malawian toddlers

Dominik Glinz, Moses Kamiyango, Kamija S Phiri, Francis Munthali, Christophe Zeder, Michael B Zimmermann, Richard F Hurrell, Rita Wegmüller

Open Access Research

Determinants of the use of insecticide-treated bed nets on islands of pre- and post-malaria elimination: an application of the health belief model in Vanuatu

Noriko Watanabe, Akira Kaneko, Sam Yamar, Hope Leodoro, George Taleo, Takeo Tanihata, J Koji Lum, Peter S Larson

Open Access Research

Does socio-economic status explain the differentials in malaria parasite prevalence? Evidence from The Gambia

Sheriff T Sonko, Malanding Jaiteh, James Jafali, Lamin BS Jarju, Umberto D’Alessandro, Abu Camara, Musu Komma-Bah, Alieu Saho

Open Access Research

Metal-chloroquine derivatives as possible anti-malarial drugs: evaluation of anti-malarial activity and mode of action

Maribel Navarro, William Castro, Marilyn Madamet, Rémy Amalvict, Nicolas Benoit, Bruno Pradines

Open Access Research

Limited polymorphisms in k13 gene in Plasmodium falciparum isolates from Dakar, Senegal in 2012–2013

Marylin Torrentino-Madamet, Bécaye Fall, Nicolas Benoit, Cheikhou Camara, Rémy Amalvict, Mansour Fall, Pierre Dionne, Kadidiatou Ba Fall, Aminata Nakoulima, Bakary Diatta, Yaya Diemé, Didier Ménard, Boubacar Wade, Bruno Pradines

Open Access Research

In vitro activity of immunosuppressive drugs against Plasmodium falciparum

Luzia Veletzky, Khalid Rehman, Tilman Lingscheid, Wolfgang Poeppl, Felix Loetsch, Heinz Burgmann, Michael Ramharter

Open Access Research

Epidemiology of malaria in a village in the Rufiji River Delta, Tanzania: declining transmission over 25 years revealed by different parasitological metrics

Anna Färnert, Victor Yman, Manijeh Vafa Homann, Grace Wandell, Leah Mhoja, Marita Johansson, Salome Jesaja, Johanna Sandlund, Kazuyuki Tanabe, Ulf Hammar, Matteo Bottai, Zulfiqarali G Premji, Anders Björkman, Ingegerd Rooth

Open Access Research

PET-PCR method for the molecular detection of malaria parasites in a national malaria surveillance study in Haiti, 2011

Naomi W Lucchi, Mara A Karell, Ito Journel, Eric Rogier, Ira Goldman, Dragan Ljolje, Curtis Huber, Kimberly E Mace, Samuel E Jean, Eniko E Akom, Roland Oscar, Josiane Buteau, Jacques Boncy, John W Barnwell, Venkatachalam Udhayakumar

Open Access Research

Diversity-oriented synthesis and activity evaluation of substituted bicyclic lactams as anti-malarial against Plasmodium falciparum

Vijeta Sharma, Shalini Agarwal, Sanjay M Madurkar, Gaurav Datta, Poonam Dangi, Ramu Dandugudumula, Subhabrata Sen, Shailja Singh

Open Access Research

Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development

Sabrina D Lamour, Ursula Straschil, Jasmina Saric, Michael J Delves

Open Access Research

The effect of intermittent preventive treatment on anti-malarial drug resistance spread in areas with population movement

Miranda I Teboh-Ewungkem, Jemal Mohammed-Awel, Frederick N Baliraine, Scott M Duke-Sylvester

Open Access Research

Therapeutic efficacy of artemether-lumefantrine on treatment of uncomplicated Plasmodium falciparum mono-infection in an area of high malaria transmission in Zambia

Busiku Hamainza, Freddie Masaninga, Hawela Moonga, Mulenga Mwenda, Pascalina Chanda-kapata, Victor Chalwe, Emmanuel Chanda, Mulakwa Kamuliwo, Olusegun Ayorinde Babaniyi

Open Access Research

Nationwide evaluation of malaria infections, morbidity, mortality, and coverage of malaria control interventions in Madagascar

Thomas Kesteman, Milijaona Randrianarivelojosia, Chiarella Mattern, Emma Raboanary, Dolorès Pourette, Florian Girond, Vaomalala Raharimanga, Laurence Randrianasolo, Patrice Piola, Christophe Rogier

Open Access Research

Insecticide-treated net use before and after mass distribution in a fishing community along Lake Victoria, Kenya: successes and unavoidable pitfalls

Peter S Larson, Noboru Minakawa, Gabriel O Dida, Sammy M Njenga, Edward L Ionides, Mark L Wilson

Open Access Research

Cost-effectiveness of larviciding for urban malaria control in Tanzania

Mathieu Maheu-Giroux, Marcia C Castro

Open Access Research

Circulating antibodies against Plasmodium falciparum histidine-rich proteins 2 interfere with antigen detection by rapid diagnostic tests

Mei-Fong Ho, Joanne Baker, Nelson Lee, Jennifer Luchavez, Frédéric Ariey, Sina Nhem, Wellington Oyibo, David Bell, Iveth González, Peter Chiodini, Michelle L Gatton, Qin Cheng, James S McCarthy

Open Access Research

PfRON3 is an erythrocyte-binding protein and a potential blood-stage vaccine candidate antigen

Xin Zhao, Zhiguang Chang, Zhiwei Tu, Shengchao Yu, Xiaoyan Wei, Jianhua Zhou, Huijun Lu, Ning Jiang, Qijun Chen

Open Access Research

Lambda-carrageenan treatment exacerbates the severity of cerebral malaria caused by Plasmodium berghei ANKA in BALB/c mice

Frances C Recuenco, Ryo Takano, Shiori Chiba, Tatsuki Sugi, Hitoshi Takemae, Fumi Murakoshi, Akiko Ishiwa, Atsuko Inomata, Taisuke Horimoto, Yoshiyasu Kobayashi, Noriyuki Horiuchi, Kentaro Kato

Open Access Research

Participation of irradiated Anopheles arabiensis males in swarms following field release in Sudan

Tellal B Ageep, David Damiens, Bashir Alsharif, Ayman Ahmed, Elwaleed HO Salih, Fayez TA Ahmed, Abdoulaye Diabaté, Rosemary S Lees, Jeremie RL Gilles, Badria B El Sayed

Open Access Review

Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria

Nicholas J White, Elizabeth A Ashley, Judith Recht, Michael J Delves, Andrea Ruecker, Frank M Smithuis, Alice C Eziefula, Teun Bousema, Chris Drakeley, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Jetsumon Prachumsri, Cindy Chu, Chiara Andolina, Germana Bancone, Tran T Hien, Mayfong Mayxay, Walter RJ Taylor, Lorenz von Seidlein, Ric N Price, Karen I Barnes, Abdoulaye Djimdé, Feiko ter Kuile, Roly Gosling, Ingrid Chen, Mehul J Dhorda, Kasia Stepniewska, Philippe Guérin, Charles J Woodrow, Arjen M Dondorp, Nicholas PJ Day, Francois H Nosten

Open Access Commentary

Fun with maths: exploring implications of mathematical models for malaria eradication

Philip A Eckhoff, Caitlin A Bever, Jaline Gerardin, Edward A Wenger

Open Access Case report

The clinical and public health problem of relapse despite primaquine therapy: case review of repeated relapses of Plasmodium vivax acquired in Papua New Guinea

R Joan H Ingram, Chelzie Crenna-Darusallam, Saraswati Soebianto, Rintis Noviyanti, J Kevin Baird

Open Access Research

Heterogeneous genetic diversity pattern in Plasmodium vivax genes encoding merozoite surface proteins (MSP) -7E, −7F and -7L

Diego Garzón-Ospina, Johanna Forero-Rodríguez, Manuel A Patarroyo

Open Access Commentary

Composite endpoints for malaria case-management: not simplifying the picture?

Matthew E Cairns, Baptiste Leurent, Paul J Milligan

Open Access Methodology

Evaluating the efficacy of biological and conventional insecticides with the new ‘MCD bottle’ bioassay

Eleanore D Sternberg, Jessica L Waite, Matthew B Thomas

Open Access Research

Strengthening malaria diagnosis and appropriate treatment in Namibia: a test of case management training interventions in Kavango Region

Christopher Lourenço, Deepika Kandula, Leena Haidula, Abigail Ward, Justin M Cohen

Open Access Research

“It is about how the net looks”: a qualitative study of perceptions and practices related to mosquito net care and repair in two districts in eastern Uganda

Leah Scandurra, Angela Acosta, Hannah Koenker, Daniel Musoke Kibuuka, Steven Harvey

Open Access Review

The duration of Plasmodium falciparum infections

Elizabeth A Ashley, Nicholas J White

Open Access Research

Pregnant women are a reservoir of malaria transmission in Blantyre, Malawi

Sarah Boudová, Lauren M Cohee, Linda Kalilani-Phiri, Phillip C Thesing, Steve Kamiza, Atis Muehlenbachs, Terrie E Taylor, Miriam K Laufer

Open Access Research

Enantioselective metabolism of primaquine by human CYP2D6

Pius S Fasinu, Babu L Tekwani, NP Dhammika Nanayakkara, Bharathi Avula, HMT Bandara Herath, Yan-Hong Wang, Vijender R Adelli, Mahmoud A Elsohly, Shabana I Khan, Ikhlas A Khan, Brandon S Pybus, Sean R Marcsisin, Gregory A Reichard, James D McChesney, Larry A Walker

Open Access Research

Pooled PCR testing strategy and prevalence estimation of submicroscopic infections using Bayesian latent class models in pregnant women receiving intermittent preventive treatment at Machinga District Hospital, Malawi, 2010

Zhiyong Zhou, Rebecca Mans Mitchell, Julie Gutman, Ryan E Wiegand, Dyson A Mwandama, Don P Mathanga, Jacek Skarbinski, Ya Ping Shi

Open Access Research

Efficacy of artesunate-amodiaquine for the treatment of acute uncomplicated falciparum malaria in southern Mauritania

Mohamed Ouldabdallahi, Ismail Alew, Mohamed Salem Ould Ahmedou Salem, Mamadou dit Dialaw Ba, Ali Ould Mohamed Salem Boukhary, Mohamed Lemine Ould Khairy, Mohamed Boubacar Abdel Aziz, Pascal Ringwald, Leonardo K Basco, Saidou Doro Niang, Sid Mohamed Lebatt

Open Access Research

Fixed dose artesunate amodiaquine – a phase IIb, randomized comparative trial with non-fixed artesunate amodiaquine

Bernhards Ogutu, Elizabeth Juma, Charles Obonyo, Vincent Jullien, Gwenaelle Carn, Michel Vaillant, Walter Robert John Taylor, Jean-René Kiechel

Open Access Research

Perceptions of malaria and acceptance of rapid diagnostic tests and related treatment practises among community members and health care providers in Greater Garissa, North Eastern Province, Kenya

Emma Diggle, Ramin Asgary, Georgia Gore-Langton, Erupe Nahashon, James Mungai, Rebecca Harrison, Abdullahi Abagira, Katie Eves, Zoya Grigoryan, David Soti, Elizabeth Juma, Richard Allan

Open Access Research

Harmonization of malaria rapid diagnostic tests: best practices in labelling including instructions for use

Jan Jacobs, Barbara Barbé, Philippe Gillet, Michael Aidoo, Elisa Serra-Casas, Jan Van Erps, Joelle Daviaud, Sandra Incardona, Jane Cunningham, Theodoor Visser

Open Access Research

A genotypically distinct, melanic variant of Anopheles arabiensi s in Sudan is associated with arid environments

Mariam Aboud, Abdelrafie Makhawi, Andrea Verardi, Fathi El Raba’a, Dia-Eldin Elnaiem, Harold Townson

Open Access Research

Microsatellite markers reveal low levels of population sub-structuring of Plasmodium falciparum in southwestern Nigeria

Muyiwa K Oyebola, Emmanuel T Idowu, Haddy Nyang, Yetunde A Olukosi, Olubunmi A Otubanjo, Davis C Nwakanma, Samson T Awolola, Alfred Amambua-Ngwa

Open Access Research

Natural variation in virulence of the entomopathogenic fungus Beauveria bassiana against malaria mosquitoes

Claudio A Valero-Jiménez, Alfons JM Debets, Jan AL van Kan, Sijmen E Schoustra, Willem Takken, Bas J Zwaan, Constantianus JM Koenraadt

Open Access Research

Application of principal component analysis to multispectral-multimodal optical image analysis for malaria diagnostics

Dickson L Omucheni, Kenneth A Kaduki, Wallace D Bulimo, Hudson K Angeyo

Open Access Research

Severe vivax malaria: a systematic review and meta-analysis of clinical studies since 1900

Bilal Ahmad Rahimi, Ammarin Thakkinstian, Nicholas J White, Chukiat Sirivichayakul, Arjen M Dondorp, Watcharee Chokejindachai

Open Access Research

Efficacy and safety of a combination of azithromycin and chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in two multi-country randomised clinical trials in African adults

Issaka Sagara, Abraham R Oduro, Modest Mulenga, Yemou Dieng, Bernhards Ogutu, Alfred B Tiono, Peter Mugyenyi, Ali Sie, Monique Wasunna, Kevin C Kain, Abdoulaye A Djimdé, Shirsendu Sarkar, Richa Chandra, Jeffery Robbins, Michael W Dunne

Open Access Research

Community knowledge and practices regarding malaria and long-lasting insecticidal nets during malaria elimination programme in an endemic area in Iran

Mussa Soleimani-Ahmadi, Hassan Vatandoost, Mehdi Zare, Ali Alizadeh, Mehrdad Salehi

Open Access Research

Plasmodium falciparum merozoite surface protein 2: epitope mapping and fine specificity of human antibody response against non-polymorphic domains

Saidou Balam, Sope Olugbile, Catherine Servis, Mahamadou Diakité, Alba D’Alessandro, Geraldine Frank, Remy Moret, Issa Nebie, Marcel Tanner, Ingrid Felger, Thomas Smith, Andrey V Kajava, François Spertini, Giampietro Corradin

Open Access Research

Comparing Leishman and Giemsa staining for the assessment of peripheral blood smear preparations in a malaria-endemic region in India

Sanghamitra Sathpathi, Akshaya K Mohanty, Parthasarathi Satpathi, Saroj K Mishra, Prativa K Behera, Goutam Patel, Arjen M Dondorp

Open Access Research

Efficacy of intranasal administration of artesunate in experimental cerebral malaria

Anne Marijon, Guillaume Bonnot, Anthony Fourier, Coralie Bringer, Adeline Lavoignat, Marie-Claude Gagnieu, Anne-Lise Bienvenu, Stéphane Picot

Open Access Research

Strengthening malaria service delivery through supportive supervision and community mobilization in an endemic Indian setting: an evaluation of nested delivery models

Ashis Das, Jed Friedman, Eeshani Kandpal, Gandham N V Ramana, Rudra Kumar Das Gupta, Madan M Pradhan, Ramesh Govindaraj

Open Access Research

Fine-scale malaria risk mapping from routine aggregated case data

Hugh JW Sturrock, Justin M Cohen, Petr Keil, Andrew J Tatem, Arnaud Le Menach, Nyasatu E Ntshalintshali, Michelle S Hsiang, Roland D Gosling

Open Access Research

Re-evaluation of microscopy confirmed Plasmodium falciparum and Plasmodium vivax malaria by nested PCR detection in southern Ethiopia

Seleshi Kebede Mekonnen, Abraham Aseffa, Girmay Medhin, Nega Berhe, Thirumalaisamy P Velavan

Open Access Research

In vitro studies on the sensitivity pattern of Plasmodium falciparum to anti-malarial drugs and local herbal extracts

Grace I Olasehinde, Olusola Ojurongbe, Adegboyega O Adeyeba, Obasola E Fagade, Neena Valecha, Isaac O Ayanda, Adesola A Ajayi, Louis O Egwari

Open Access Research

Estimation of insecticide persistence, biological activity and mosquito resistance to PermaNet® 2 long-lasting insecticidal nets over three to 32 months of use in Ethiopia

Gedeon Yohannes Anshebo, Patricia M Graves, Stephen C Smith, Aprielle B Wills, Mesele Damte, Tekola Endeshaw, Estifanos Biru Shargie, Teshome Gebre, Aryc W Mosher, Amy E Patterson, Paul M Emerson

Open Access Case report

Plasmodium ovale: a case of not-so-benign tertian malaria

Kathy-Anne Strydom, Farzana Ismail, John Frean

Open Access Research

Field evaluation of an automated RDT reader and data management device for Plasmodium falciparum/Plasmodium vivax malaria in endemic areas of Colombia

Sócrates Herrera, Andrés F Vallejo, Juan P Quintero, Myriam Arévalo-Herrera, Marcela Cancino, Santiago Ferro

Open Access Case study

A description of malaria sentinel surveillance: a case study in Oromia Regional State, Ethiopia

Joshua O Yukich, Jessica Butts, Melody Miles, Yemane Berhane, Honelgn Nahusenay, Joseph L Malone, Gunawardena Dissanayake, Richard Reithinger, Joseph Keating

Open Access Methodology

Pre-amplification methods for tracking low-grade Plasmodium falciparum populations during scaled-up interventions in Southern Zambia

Sungano Mharakurwa, Rachel Daniels, Alan Scott, Dyann F Wirth, Philip Thuma, Sarah K Volkman

Open Access Research

In vitro and in vivo combination of cepharanthine with anti-malarial drugs

Camille Desgrouas, Jérôme Dormoi, Charles Chapus, Evelyne Ollivier, Daniel Parzy, Nicolas Taudon

Open Access Methodology

Evaluating local vegetation cover as a risk factor for malaria transmission: a new analytical approach using ImageJ

Emily E Ricotta, Steven A Frese, Cornelius Choobwe, Thomas A Louis, Clive J Shiff

Open Access Methodology

Validation of the ligase detection reaction fluorescent microsphere assay for the detection of Plasmodium falciparum resistance mediating polymorphisms in Uganda

Sheila Nankoberanyi, George W Mbogo, Norbert P LeClair, Melissa D Conrad, Patrick Tumwebaze, Stephen Tukwasibwe, Moses R Kamya, Jordan Tappero, Samuel L Nsobya, Philip J Rosenthal

Open Access Research

Effects of modifying the World Health Organization standard operating procedures for malaria microscopy to improve surveillance in resource poor settings

Sumadhya D Fernando, Ratnasiri L Ihalamulla, Renu Wickremasinghe, Nipun L de Silva, Janani H Thilakarathne, Pandu Wijeyaratne, Risintha G Premaratne

Open Access Methodology

A flow cytometric assay to quantify invasion of red blood cells by rodent Plasmodium parasites in vivo

Patrick M Lelliott, Shelley Lampkin, Brendan J McMorran, Simon J Foote, Gaetan Burgio

Open Access Research

Paracheck® rapid diagnostic test for detecting malaria infection in under five children: a population-based survey in Burkina Faso

Sekou Samadoulougou, Fati Kirakoya-Samadoulougou, Sophie Sarrassat, Halidou Tinto, Fidèle Bakiono, Issa Nebié, Annie Robert

Open Access Research

Anti-sporozoite antibodies as alternative markers for malaria transmission intensity estimation

Kwadwo A Kusi, Samuel Bosomprah, Daniel Dodoo, Eric Kyei-Baafour, Emmanuel K Dickson, Daniel Mensah, Evelina Angov, Sheetij Dutta, Martha Sedegah, Kwadwo A Koram

Open Access Research

Liver changes in severe Plasmodium falciparum malaria: histopathology, apoptosis and nuclear factor kappa B expression

Parnpen Viriyavejakul, Vasant Khachonsaksumet, Chuchard Punsawad

Open Access Research

Quantifying cross-border movements and migrations for guiding the strategic planning of malaria control and elimination

Deepa K Pindolia, Andres J Garcia, Zhuojie Huang, Timothy Fik, David L Smith, Andrew J Tatem

Open Access Research

Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria

Katherine Plewes, Annick A Royakkers, Josh Hanson, Md Mahtab Uddin Hasan, Shamsul Alam, Aniruddha Ghose, Richard J Maude, Pauline M Stassen, Prakaykaew Charunwatthana, Sue J Lee, Gareth DH Turner, Arjen M Dondorp, Marcus J Schultz

Open Access Case report

Blackwater fever in an uncomplicated Plasmodium falciparum patient treated with dihydroartemisinin-piperaquine

Chanthap Lon, Michele Spring, Somethy Sok, Soklyda Chann, Rathvichet Bun, Mali Ittiverakul, Nillawan Buathong, Khengheng Thay, Nareth Kong, Yom You, Worachet Kuntawunginn, Charlotte A Lanteri, David L Saunders

Open Access Methodology

Rapid detection of Plasmodium falciparum with isothermal recombinase polymerase amplification and lateral flow analysis

Sebastian Kersting, Valentina Rausch, Frank Fabian Bier, Markus von Nickisch-Rosenegk

Open Access Methodology

Estimation of malaria haplotype and genotype frequencies: a statistical approach to overcome the challenge associated with multiclonal infections

Aimee R Taylor, Jennifer A Flegg, Samuel L Nsobya, Adoke Yeka, Moses R Kamya, Philip J Rosenthal, Grant Dorsey, Carol H Sibley, Philippe J Guerin, Chris C Holmes

Open Access Research

Polymorphic patterns of the merozoite surface protein-3β in Korean isolates of Plasmodium vivax

Jung-Mi Kang, Hye-Lim Ju, Pyo Yun Cho, Sung-Ung Moon, Seong Kyu Ahn, Woon-Mok Sohn, Hyeong-Woo Lee, Tong-Soo Kim, Byoung-Kuk Na

Open Access Research

Association of the endothelial protein C receptor (PROCR) rs867186-G allele with protection from severe malaria

Izumi Naka, Jintana Patarapotikul, Hathairad Hananantachai, Hiroo Imai, Jun Ohashi

Open Access Research

A push-pull system to reduce house entry of malaria mosquitoes

David J Menger, Bruno Otieno, Marjolein de Rijk, W Richard Mukabana, Joop JA van Loon, Willem Takken

Open Access Methodology

Optimizing the programmatic deployment of the anti-malarials artemether-lumefantrine and dihydroartemisinin-piperaquine using pharmacological modelling

Eva Maria Hodel, Katherine Kay, Daniel J Hayes, Dianne J Terlouw, Ian M Hastings

Open Access Review

Made-to-measure malaria vector control strategies: rational design based on insecticide properties and coverage of blood resources for mosquitoes

Gerry F Killeen, Aklilu Seyoum, John E Gimnig, Jennifer C Stevenson, Christopher J Drakeley, Nakul Chitnis

Open Access Research

Return of chloroquine-sensitive Plasmodium falciparum parasites and emergence of chloroquine-resistant Plasmodium vivax in Ethiopia

Seleshi Kebede Mekonnen, Abraham Aseffa, Nega Berhe, Tilahun Teklehaymanot, Ronald M Clouse, Tamirat Gebru, Girmay Medhin, Thirumalaisamy P Velavan

Open Access Erratum

Erratum to: Anti-malarial activity and HS-SPME-GC-MS chemical profiling of Plinia cerrocampanensis leaf essential oil

Armando A Durant, Candelario Rodríguez, Liuris Herrera, Alejandro Almanza, Ana I Santana, Carmenza Spadafora, Mahabir P Gupta

Open Access Research

Spatial and temporal epidemiology of clinical malaria in Cambodia 2004–2013

Richard J Maude, Chea Nguon, Po Ly, Tol Bunkea, Pengby Ngor, Sara E Canavati de la Torre, Nicholas J White, Arjen M Dondorp, Nicholas PJ Day, Lisa J White, Char Meng Chuor

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