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Malaria Journal

Ausgabe 1/2016

Inhalt (598 Artikel)

Open Access Research

Spatially variable risk factors for malaria in a geographically heterogeneous landscape, western Kenya: an explorative study

Tobias Homan, Nicolas Maire, Alexandra Hiscox, Aurelio Di Pasquale, Ibrahim Kiche, Kelvin Onoka, Collins Mweresa, Wolfgang R. Mukabana, Amanda Ross, Thomas A. Smith, Willem Takken

Open Access Research

Strategies and approaches to vector control in nine malaria-eliminating countries: a cross-case study analysis

Cara Smith Gueye, Gretchen Newby, Roland D. Gosling, Maxine A. Whittaker, Daniel Chandramohan, Laurence Slutsker, Marcel Tanner

Open Access Methodology

Plasmodium berghei bio-burden correlates with parasite lactate dehydrogenase: application to murine Plasmodium diagnostics

Sai Lata De, Danielle I. Stanisic, Fabian Rivera, Michael R. Batzloff, Christian Engwerda, Michael F. Good

Open Access Research

Status of the use and compliance with malaria rapid diagnostic tests in formal private health facilities in Nigeria

Olugbenga A. Mokuolu, Godwin N. Ntadom, Olufemi O. Ajumobi, Roberts A. Alero, Robinson D. Wammanda, Olanrewaju T. Adedoyin, Henrietta U. Okafor, Adekunle D. Alabi, Friday A. Odey, Chimere O. Agomo, Kate U. Edozieh, Tolulope O. Fagbemi, Ahmad M. Njidda, Seye Babatunde, Emmanuel C. Agbo, Nnamdi B. Nwaneri, Emmanuel D. Shekarau, Temitope O. Obasa, Nnenna M. Ezeigwe

Open Access Commentary

The Cambodia Research Consortium: expediting research for malaria elimination with the emergency response to artemisinin resistance framework

Sara E. Canavati, Harriet L. S. Lawford, Bayo S. Fatunmbi, Dysoley Lek, Rithea Leang, Narann Top Samphor, Arjen M. Dondorp, Rekol Huy, Walter M. Kazadi

Open Access Research

Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine combinations in the treatment of uncomplicated malaria in two ecological zones in Ghana

Benjamin Abuaku, Nancy Duah, Lydia Quaye, Neils Quashie, Keziah Malm, Constance Bart-Plange, Kwadwo Koram

Open Access Research

Pharmacokinetics of mefloquine and its effect on sulfamethoxazole and trimethoprim steady-state blood levels in intermittent preventive treatment (IPTp) of pregnant HIV-infected women in Kenya

Michael Green, Kephas Otieno, Abraham Katana, Laurence Slutsker, Simon Kariuki, Peter Ouma, Raquel González, Clara Menendez, Feiko ter Kuile, Meghna Desai

Open Access Case Report

Diagnosis of an imported Plasmodium ovale wallikeri infection in Malaysia

Jonathan Wee Kent Liew, Rohela Mahmud, Lian Huat Tan, Yee Ling Lau

Open Access Research

Assessing the potential impact of artemisinin and partner drug resistance in sub-Saharan Africa

Hannah C. Slater, Jamie T. Griffin, Azra C. Ghani, Lucy C. Okell

Open Access Research

Epidemiology of malaria in the Taabo health and demographic surveillance system, south-central Côte d’Ivoire

Fidèle K. Bassa, Mamadou Ouattara, Kigbafori D. Silué, Lukas G. Adiossan, Nahoua Baikoro, Siaka Koné, Moussan N’Cho, Mahamadou Traoré, Bassirou Bonfoh, Jürg Utzinger, Eliézer K. N’Goran

Open Access Case Study

Targeting indoor residual spraying for malaria using epidemiological data: a case study of the Zambia experience

Jessie Pinchoff, David A. Larsen, Silvia Renn, Derek Pollard, Christen Fornadel, Mark Maire, Chadwick Sikaala, Chomba Sinyangwe, Benjamin Winters, Daniel J. Bridges, Anna M. Winters

Open Access Research

A common TLR1 polymorphism is associated with higher parasitaemia in a Southeast Asian population with Plasmodium falciparum malaria

William O. Hahn, Susanna Harju-Baker, Laura K. Erdman, Srivicha Krudsood, Kevin C. Kain, Mark M. Wurfel, Wayne C. Liles

Open Access Research

Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria

Shivang S. Shah, Kirk A. Rockett, Muminatou Jallow, Fatou Sisay-Joof, Kalifa A. Bojang, Margaret Pinder, Anna Jeffreys, Rachel Craik, Christina Hubbart, Thomas E. Wellems, Dominic P. Kwiatkowski

Open Access Research

The role of gender on malaria preventive behaviour among rural households in Kenya

Gracious M. Diiro, Hippolyte D. Affognon, Beatrice W. Muriithi, Sarah Kingori Wanja, Charles Mbogo, Clifford Mutero

Open Access Research

Alterations of blood coagulation in controlled human malaria infection

Julia Riedl, Benjamin Mordmüller, Silvia Koder, Ingrid Pabinger, Peter G. Kremsner, Stephen L. Hoffman, Michael Ramharter, Cihan Ay

Open Access Research

Malaria burden and anti-malarial drug efficacy in Owando, northern Congo

Brice P. Singana, Hervé Bogreau, Brunelle D. Matondo, Louis R. Dossou-Yovo, Prisca N. Casimiro, Rigobert Mbouka, Kim Yen Ha Nguyen, Bruno Pradines, Leonardo K. Basco, Mathieu Ndounga

Open Access Research

Antibody profiles to plasmodium merozoite surface protein-1 in Cambodian adults during an active surveillance cohort with nested treatment study

Michele D. Spring, Sathit Pichyangkul, Chanthap Lon, Panita Gosi, Kosol Yongvanichit, Utaiwan Srichairatanakul, Amporn Limsalakpeth, Chaiyaporn Chaisatit, Soklyda Chann, Sabaithip Sriwichai, Montida Auayapon, Suwanna Chaorattanakawee, Sheetij Dutta, Satharath Prom, Char Meng Chour, Douglas S. Walsh, Evelina Angov, David L. Saunders

Open Access Research

Feasibility and acceptability of injectable artesunate for the treatment of severe malaria in the Democratic Republic of Congo

Henry M. T. Ntuku, Gianfrancesco Ferrari, Christian Burri, Antoinette K. Tshefu, Didier M. Kalemwa, Christian Lengeler

Open Access Research

Treatment-seeking rates in malaria endemic countries

Katherine E. Battle, Donal Bisanzio, Harry S. Gibson, Samir Bhatt, Ewan Cameron, Daniel J. Weiss, Bonnie Mappin, Ursula Dalrymple, Rosalind E. Howes, Simon I. Hay, Peter W. Gething

Open Access Research

A yeast strain associated to Anopheles mosquitoes produces a toxin able to kill malaria parasites

Matteo Valzano, Valentina Cecarini, Alessia Cappelli, Aida Capone, Jovana Bozic, Massimiliano Cuccioloni, Sara Epis, Dezemona Petrelli, Mauro Angeletti, Anna Maria Eleuteri, Guido Favia, Irene Ricci

Open Access Erratum

Erratum to: Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding

Sofia Nunes-Silva, Sébastien Dechavanne, Azizath Moussiliou, Natalia Pstrąg, Jean-Philippe Semblat, Stéphane Gangnard, Nicaise Tuikue-Ndam, Philippe Deloron, Arnaud Chêne, Benoît Gamain

Open Access Research

Why do health workers give anti-malarials to patients with negative rapid test results? A qualitative study at rural health facilities in western Uganda

Robin Altaras, Anthony Nuwa, Bosco Agaba, Elizabeth Streat, James K. Tibenderana, Clare E. Strachan

Open Access Research

Malaria transmission dynamics surrounding the first nationwide long-lasting insecticidal net distribution in Papua New Guinea

Lisa J. Reimer, Edward K. Thomsen, Gussy Koimbu, John B. Keven, Ivo Mueller, Peter M. Siba, James W. Kazura, Manuel W. Hetzel, Peter A. Zimmerman

Open Access Research

Sickle haemoglobin, haemoglobin C and malaria mortality feedbacks

Bronner P. Gonçalves, Sunetra Gupta, Bridget S. Penman

Open Access Research

A malaria risk map of Kinshasa, Democratic Republic of Congo

Giovanfrancesco Ferrari, Henry M. Ntuku, Sandro Schmidlin, Eric Diboulo, Antoinette K. Tshefu, Christian Lengeler

Open Access Research

Functional analysis of monoclonal antibodies against the Plasmodium falciparum PfEMP1-VarO adhesin

Micheline Guillotte, Farida Nato, Alexandre Juillerat, Audrey Hessel, Françoise Marchand, Anita Lewit-Bentley, Graham A. Bentley, Inès Vigan-Womas, Odile Mercereau-Puijalon

Open Access Research

Distribution of FcγR gene polymorphisms among two sympatric populations in Mali: differing allele frequencies, associations with malariometric indices and implications for genetic susceptibility to malaria

Mariama Cherif, Daniel Amoako-Sakyi, Amagana Dolo, Jan-Olov Pearson, Ben Gyan, Dorcas Obiri-Yeboah, Issa Nebie, Sodiomon B. Sirima, Ogobara Doumbo, Marita Troye-Blomberg, Maiga Bakary

Open Access Research

UTR introns, antisense RNA and differentially spliced transcripts between Plasmodium yoelii subspecies

Jian Li, Baowei Cai, Yanwei Qi, Wenting Zhao, Jianwen Liu, Ruixue Xu, Qin Pang, Zhiyong Tao, Lingxian Hong, Shengfa Liu, Maarten Leerkes, Mariam Quiñones, Xin-zhuan Su

Open Access Research

Field evaluation of the 22 rapid diagnostic tests for community management of malaria with artemisinin combination therapy in Cameroon

Innocent M. Ali, Jude D. Bigoga, Dorothy A. Forsah, Fidelis Cho-Ngwa, Vivian Tchinda, Vicky Ama Moor, Josephine Fogako, Philomena Nyongalema, Theresa Nkoa, Albert Same-Ekobo, Joseph Mbede, Etienne Fondjo, Wilfred F. Mbacham, Rose G. F. Leke

Open Access Research

Localization and interactions of Plasmodium falciparum SWIB/MDM2 homologues

Warren Antonio Vieira, Thérèsa L. Coetzer

Open Access Research

In vitro adaptation of Plasmodium falciparum reveal variations in cultivability

John White III, Anjali Mascarenhas, Ligia Pereira, Rashmi Dash, Jayashri T. Walke, Pooja Gawas, Ambika Sharma, Suresh Kumar Manoharan, Jennifer L. Guler, Jennifer N. Maki, Ashwani Kumar, Jagadish Mahanta, Neena Valecha, Nagesh Dubhashi, Marina Vaz, Edwin Gomes, Laura Chery, Pradipsinh K. Rathod

Open Access Research

Malaria case detection using rapid diagnostic test at the community level in Ghana: consumer perception and practitioners’ experiences

Daniel A. Danquah, Kwame O. Buabeng, Kwaku P. Asante, Emmanuel Mahama, Constance Bart-Plange, Ellis Owusu-Dabo

Open Access Research

Epidemiological and entomological studies of a malaria outbreak among French armed forces deployed at illegal gold mining sites reveal new aspects of the disease’s transmission in French Guiana

Vincent Pommier de Santi, Romain Girod, Marie Mura, Aissata Dia, Sébastien Briolant, Félix Djossou, Isabelle Dusfour, Alexandre Mendibil, Fabrice Simon, Xavier Deparis, Frédéric Pagès

Open Access Research

Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children

Julian Muwanguzi, Gisela Henriques, Patrick Sawa, Teun Bousema, Colin J. Sutherland, Khalid B. Beshir

Open Access Research

Therapeutic efficacy of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Benin

Aurore Ogouyèmi-Hounto, Christian Azandossessi, Souliatou Lawani, Georgia Damien, Yolande Sissinto Savi de Tove, Franck Remoue, Dorothée Kinde Gazard

Open Access Research

Characteristics of asymptomatic Plasmodium spp. parasitaemia in Kwahu-Mpraeso, a malaria endemic mountainous district in Ghana, West Africa

Ewurama D. A. Owusu, Vincent Buabeng, Samuel Dadzie, Charles A. Brown, Martin P. Grobusch, Petra Mens

Open Access Research

Trends of imported malaria in China 2010–2014: analysis of surveillance data

Sheng Zhou, Zhongjie Li, Chris Cotter, Canjun Zheng, Qian Zhang, Huazhong Li, Shuisen Zhou, Xiaonong Zhou, Hongjie Yu, Weizhong Yang

Open Access Research

Malaria community health workers in Myanmar: a cost analysis

Shwe Sin Kyaw, Tom Drake, Aung Thi, Myat Phone Kyaw, Thaung Hlaing, Frank M. Smithuis, Lisa J. White, Yoel Lubell

Open Access Research

Comparison of the safety and efficacy of fixed-dose combination of arterolane maleate and piperaquine phosphate with chloroquine in acute, uncomplicated Plasmodium vivax malaria: a phase III, multicentric, open-label study

Neena Valecha, Deepali Savargaonkar, Bina Srivastava, B. H. Krishnamoorthy Rao, Santanu K. Tripathi, Nithya Gogtay, Sanjay Kumar Kochar, Nalli Babu Vijaya Kumar, Girish Chandra Rajadhyaksha, Jitendra D. Lakhani, Bhagirath B. Solanki, Rajinder K. Jalali, Sudershan Arora, Arjun Roy, Nilanjan Saha, Sunil S. Iyer, Pradeep Sharma, Anupkumar R. Anvikar

Open Access Research

Treatment outcomes in a safety observational study of dihydroartemisinin/piperaquine (Eurartesim®) in the treatment of uncomplicated malaria at public health facilities in four African countries

Alexander Adjei, Solomon Narh-Bana, Alberta Amu, Vida Kukula, Richard Afedi Nagai, Seth Owusu-Agyei, Abraham Oduro, Eusebio Macete, Salim Abdulla, Tinto Halidou, Ali Sie, Isaac Osei, Esperance Sevene, Kwaku-Poku Asante, Abdunoor Mulokozi, Guillaume Compaore, Innocent Valea, Martin Adjuik, Rita Baiden, Bernhards Ogutu, Fred Binka, Margaret Gyapong

Open Access Research

What drives the consistent use of long-lasting insecticidal nets over time? A multi-method qualitative study in mid-western Uganda

Clare E. Strachan, Anthony Nuwa, Denis Muhangi, Albert P. Okui, Michelle E. H. Helinski, James K. Tibenderana

Open Access Research

The risk of malaria in Ghanaian infants born to women managed in pregnancy with intermittent screening and treatment for malaria or intermittent preventive treatment with sulfadoxine/pyrimethamine

Timothy Awine, Mark M. Belko, Abraham R. Oduro, Sunny Oyakhirome, Harry Tagbor, Daniel Chandramohan, Paul Milligan, Matthew Cairns, Brian Greenwood, John E. Williams

Open Access Research

Concurrent malaria and arbovirus infections in Kedougou, southeastern Senegal

Abdourahmane Sow, Cheikh Loucoubar, Diawo Diallo, Oumar Faye, Youssoupha Ndiaye, Cheikh Saadibou Senghor, Anta Tal Dia, Ousmane Faye, Scott C. Weaver, Mawlouth Diallo, Denis Malvy, Amadou Alpha Sall

Open Access Research

Plasmodium vivax gametocyte infectivity in sub-microscopic infections

Andrés F. Vallejo, Jhon García, Andrés B. Amado-Garavito, Myriam Arévalo-Herrera, Sócrates Herrera

Open Access Research

Field evaluation of a PfHRP-2/pLDH rapid diagnostic test and light microscopy for diagnosis and screening of falciparum malaria during the peak seasonal transmission in an endemic area in Yemen

Lina M. Q. Alareqi, Mohammed A. K. Mahdy, Yee-Ling Lau, Mun-Yik Fong, Rashad Abdul-Ghani, Arwa A. Ali, Fei-Wen Cheong, Rehab Tawfek, Rohela Mahmud

Open Access Research

Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites

Patrath Ponsuwanna, Theerarat Kochakarn, Duangkamon Bunditvorapoom, Krittikorn Kümpornsin, Thomas D. Otto, Chase Ridenour, Kesinee Chotivanich, Prapon Wilairat, Nicholas J. White, Olivo Miotto, Thanat Chookajorn

Open Access Research

Performance and user acceptance of the Bhutan febrile and malaria information system: report from a pilot study

Tashi Tobgay, Pema Samdrup, Thinley Jamtsho, Kylie Mannion, Leonard Ortega, Amnat Khamsiriwatchara, Ric N. Price, Kamala Thriemer, Jaranit Kaewkungwal

Open Access Research

Non-falciparum malaria infections in pregnant women in West Africa

John Williams, Fanta Njie, Matthew Cairns, Kalifa Bojang, Sheick Oumar Coulibaly, Kassoum Kayentao, Ismaela Abubakar, Francis Akor, Khalifa Mohammed, Richard Bationo, Edgar Dabira, Alamissa Soulama, Moussa Djimdé, Etienne Guirou, Timothy Awine, Stephen L. Quaye, Jaume Ordi, Ogobara Doumbo, Abraham Hodgson, Abraham Oduro, Pascal Magnussen, Feiko O. ter Kuile, Arouna Woukeu, Paul Milligan, Harry Tagbor, Brian Greenwood, Daniel Chandramohan

Open Access Research

Increased adhesion of Plasmodium falciparum infected erythrocytes to ICAM-1 in children with acute intestinal injury

James A. Church, Lydia Nyamako, Peter Olupot-Olupot, Kathryn Maitland, Britta C. Urban

Open Access Research

Measurement of ex vivo ELISpot interferon-gamma recall responses to Plasmodium falciparum AMA1 and CSP in Ghanaian adults with natural exposure to malaria

Harini Ganeshan, Kwadwo A. Kusi, Dorothy Anum, Michael R. Hollingdale, Bjoern Peters, Yohan Kim, John K. A. Tetteh, Michael F. Ofori, Ben A. Gyan, Kwadwo A. Koram, Jun Huang, Maria Belmonte, Jo Glenna Banania, Daniel Dodoo, Eileen Villasante, Martha Sedegah

Open Access Research

Endothelial activation, haemostasis and thrombosis biomarkers in Ugandan children with severe malaria participating in a clinical trial

Susan M. Graham, Junmei Chen, Dominic W. Chung, Kevin R. Barker, Andrea L. Conroy, Michael T. Hawkes, Sophie Namasopo, Kevin C. Kain, José A. López, W. Conrad Liles

Open Access Research

Multiple causes of an unexpected malaria outbreak in a high-transmission area in Madagascar

Thomas Kesteman, Solofoniaina A. Rafalimanantsoa, Harimahefa Razafimandimby, Heriniaina H. Rasamimanana, Vaomalala Raharimanga, Benjamin Ramarosandratana, Arsene Ratsimbasoa, Jocelyn Ratovonjato, Nohal Elissa, Laurence Randrianasolo, Alyssa Finlay, Christophe Rogier, Milijaona Randrianarivelojosia

Open Access Research

Multi-country comparison of delivery strategies for mass campaigns to achieve universal coverage with insecticide-treated nets: what works best?

Celine Zegers de Beyl, Hannah Koenker, Angela Acosta, Emmanuel Obi Onyefunafoa, Emmanuel Adegbe, Anna McCartney-Melstad, Richmond Ato Selby, Albert Kilian

Open Access Erratum

Erratum to: Therapeutic assessment of chloroquine–primaquine combined regimen in adult cohort of Plasmodium vivax malaria from a tertiary care hospital in southwestern India

Kumar Rishikesh, Asha Kamath, Manjunatha H. Hande, Sudha Vidyasagar, Raviraja V. Acharya, Vasudeva Acharya, Jayaprakash Belle, Ananthakrishna B. Shastry, Kavitha Saravu

Open Access Research

Partitioning the contributions of alternative malaria vector species

Anne Deredec, Samantha M. O’Loughlin, Tin-Yu J. Hui, Austin Burt

Open Access Research

Application of mosquito repellent coils and associated self-reported health issues in Ghana

Jonathan N. Hogarh, Philip Antwi-Agyei, Kwasi Obiri-Danso

Open Access Research

Mutations of pvdhfr and pvdhps genes in vivax endemic-malaria areas in Kota Marudu and Kalabakan, Sabah

Umi Rubiah Sastu, Noor Rain Abdullah, Nor Azrina Norahmad, Muhammad Nor Farhan Saat, Prem Kumar Muniandy, Jenarun Jelip, Moizin Tikuson, Norsalleh Yusof, Hasidah Mohd Sidek

Open Access Research

The complexities of simple technologies: re-imagining the role of rapid diagnostic tests in malaria control efforts

Uli Beisel, René Umlauf, Eleanor Hutchinson, Clare I. R. Chandler

Open Access Research

Acquired immune responses to three malaria vaccine candidates and their relationship to invasion inhibition in two populations naturally exposed to malaria

Otchere Addai-Mensah, Melanie Seidel, Nafiu Amidu, Dominika J. Maskus, Stephanie Kapelski, Gudrun Breuer, Carmen Franken, Ellis Owusu-Dabo, Margaret Frempong, Raphaël Rakotozandrindrainy, Helga Schinkel, Andreas Reimann, Torsten Klockenbring, Stefan Barth, Rainer Fischer, Rolf Fendel

Open Access Research

Malaria in pregnancy: a passive surveillance study of pregnant women in low transmission areas of Colombia, Latin America

Mary Lopez-Perez, M. Andreína Pacheco, Lucía Buriticá, Ananias A. Escalante, Sócrates Herrera, Myriam Arévalo-Herrera

Open Access Research

What is the value of reactive case detection in malaria control? A case-study in India and a systematic review

Anna Maria van Eijk, Lalitha Ramanathapuram, Patrick L. Sutton, Deena Kanagaraj, G. Sri Lakshmi Priya, Sangamithra Ravishankaran, Aswin Asokan, Nikunj Tandel, Ankita Patel, Nisha Desai, Ranvir Singh, Steven A. Sullivan, Jane M. Carlton, H. C. Srivastava, Alex Eapen

Open Access Research

Economic costs of fever to households in the middle belt of Ghana

Theresa Tawiah, Kwaku Poku Asante, Rebecca Akua Dwommoh, Anthony Kwarteng, Stephaney Gyaase, Emmanuel Mahama, Livesy Abokyi, Seeba Amenga-Etego, Kristian Hansen, Patricia Akweongo, Seth Owusu-Agyei

Open Access Research

Malaria, helminths, co-infection and anaemia in a cohort of children from Mutengene, south western Cameroon

Clarisse Njua-Yafi, Eric A. Achidi, Judith K. Anchang-Kimbi, Tobias O. Apinjoh, Regina N. Mugri, Hanesh F. Chi, Rolland B. Tata, Charles Njumkeng, Emmanuel N. Nkock, Theresa Nkuo-Akenji

Open Access Research

Consistent prevalence of asymptomatic infections in malaria endemic populations in Colombia over time

Juan M. Vásquez-Jiménez, Myriam Arévalo-Herrera, Juliana Henao-Giraldo, Karen Molina-Gómez, María Arce-Plata, Andrés F. Vallejo, Sócrates Herrera

Open Access Research

Community perceptions of mass screening and treatment for malaria in Siaya County, western Kenya

Kathryn Shuford, Florence Were, Norbert Awino, Aaron Samuels, Peter Ouma, Simon Kariuki, Meghna Desai, Denise Roth Allen

Open Access Research

Large-scale Anopheles arabiensis egg quantification methods for mass-rearing operations

Hamidou Maïga, David Damiens, Abdoulaye Diabaté, Roch K. Dabiré, Georges A. Ouédraogo, Rosemary S. Lees, Jeremie R. L. Gilles

Open Access Research

Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum

Phuong N. Tran, Simon H. J. Brown, Melanie Rug, Melanie C. Ridgway, Todd W. Mitchell, Alexander G. Maier

Open Access Review

Plasmodium falciparum drug resistance in Angola

Cláudia Fançony, Miguel Brito, Jose Pedro Gil

Open Access Research

Genetic diversity among Plasmodium vivax isolates along the Thai–Myanmar border of Thailand

Sarunya Maneerattanasak, Panita Gosi, Srivicha Krudsood, Jarinee Tongshoob, Charlotte A. Lanteri, Georges Snounou, Srisin Khusmith

Open Access Research

Malaria vectors and their blood-meal sources in an area of high bed net ownership in the western Kenya highlands

Bryson A. Ndenga, Nicholas L. Mulaya, Sandra K. Musaki, Joan N. Shiroko, Stefan Dongus, Ulrike Fillinger

Open Access Research

Longitudinal household surveillance for malaria in Rakai, Uganda

Kevin Newell, Valerian Kiggundu, Joseph Ouma, Enos Baghendage, Noah Kiwanuka, Ronald Gray, David Serwadda, Charlotte V. Hobbs, Sara A. Healy, Thomas C. Quinn, Steven J. Reynolds

Open Access Research

Evolution of the levels of human leukocyte antigen G (HLA-G) in Beninese infant during the first year of life in a malaria endemic area: using latent class analysis

Tania C. d’Almeida, Ibrahim Sadissou, Gilles Cottrell, Rachida Tahar, Philippe Moreau, Benoit Favier, Kabirou Moutairou, Eduardo A. Donadi, Achille Massougbodji, Nathalie Rouass-Freiss, David Courtin, André Garcia

Open Access Methodology

Estimating malaria transmission intensity from Plasmodium falciparum serological data using antibody density models

Emilie Pothin, Neil M. Ferguson, Chris J. Drakeley, Azra C. Ghani

Open Access Research

Widespread distribution of Plasmodium vivax malaria in Mauritania on the interface of the Maghreb and West Africa

Hampâté Ba, Craig W. Duffy, Ambroise D. Ahouidi, Yacine Boubou Deh, Mamadou Yero Diallo, Abderahmane Tandia, David J. Conway

Open Access Research

Malaria in children of Tshimbulu (Western Kasai, Democratic Republic of the Congo): epidemiological data and accuracy of diagnostic assays applied in a limited resource setting

Simona Gabrielli, Livia Bellina, Giovanni Luigi Milardi, Boniface Kabasele Katende, Valentina Totino, Valerio Fullin, Gabriella Cancrini

Open Access Research

Cost-effectiveness analysis of rapid diagnostic tests for G6PD deficiency in patients with Plasmodium vivax malaria in the Brazilian Amazon

Henry M. Peixoto, Marcelo A. M. Brito, Gustavo A. S. Romero, Wuelton M. Monteiro, Marcus V. G. de Lacerda, Maria R. F. de Oliveira

Open Access Research

Effectiveness of malaria control interventions in Madagascar: a nationwide case–control survey

Thomas Kesteman, Milijaona Randrianarivelojosia, Vaomalala Raharimanga, Laurence Randrianasolo, Patrice Piola, Christophe Rogier

Open Access Research

Spatial heterogeneity of malaria in Ghana: a cross-sectional study on the association between urbanicity and the acquisition of immunity

Clemens Frank, Ralf Krumkamp, Nimako Sarpong, Peter Sothmann, Julius N Fobil, Geoffrey Foli, Anna Jaeger, Lutz Ehlkes, Ellis Owusu-Dabo, Yaw Adu-Sarkodie, Florian Marks, Ralf R. Schumann, Jürgen May, Benno Kreuels

Open Access Review

Macrolides and associated antibiotics based on similar mechanism of action like lincosamides in malaria

Tiphaine Gaillard, Jérôme Dormoi, Marylin Madamet, Bruno Pradines

Open Access Meeting report

Fake anti-malarials: start with the facts

Harparkash Kaur, Siȃn Clarke, Mirza Lalani, Souly Phanouvong, Philippe Guérin, Andrew McLoughlin, Benjamin K. Wilson, Michael Deats, Aline Plançon, Heidi Hopkins, Debora Miranda, David Schellenberg

Open Access Research

Identification of blood meal sources in the main African malaria mosquito vector by MALDI-TOF MS

Sirama Niare, Jean-Michel Berenger, Constentin Dieme, Ogobara Doumbo, Didier Raoult, Philippe Parola, Lionel Almeras

Open Access Research

Synergistic anti-malarial action of cryptolepine and artemisinins

Arnold D. Forkuo, Charles Ansah, Kwesi M. Boadu, Johnson N. Boampong, Elvis O. Ameyaw, Ben A. Gyan, Andrea T. Arku, Michael F. Ofori

Open Access Research

Population pharmacokinetic properties of artemisinin in healthy male Vietnamese volunteers

Sofia Birgersson, Pham Van Toi, Nguyen Thanh Truong, Nguyen Thi Dung, Michael Ashton, Tran Tinh Hien, Angela Abelö, Joel Tarning

Open Access Research

Positive deviance as a novel tool in malaria control and elimination: methodology, qualitative assessment and future potential

Muhammad Shafique, Hannah M. Edwards, Celine Zegers De Beyl, Bou Kheng Thavrin, Myo Min, Arantxa Roca-Feltrer

Open Access Research

Timing of malaria in pregnancy and impact on infant growth and morbidity: a cohort study in Uganda

Pierre De Beaudrap, Eleanor Turyakira, Carolyn Nabasumba, Benon Tumwebaze, Patrice Piola, Yap Boum II, Rose McGready

Open Access Research

Survey of Plasmodium in the golden-headed lion tamarin (Leontopithecus chrysomelas) living in urban Atlantic forest in Rio de Janeiro, Brazil

Elizabeth Helen Aitken, Marina Galvão Bueno, Luana dos Santos Ortolan, José M. Alvaréz, Alcides Pissinatti, Maria Cecília Martins Kierulff, José Luiz Catão-Dias, Sabrina Epiphanio

Open Access Methodology

Alternative methods for the Plasmodium falciparum artemisinin ring-stage survival assay with increased simplicity and parasite stage-specificity

Whitney A. Kite, Viviana A. Melendez-Muniz, Roberto R. Moraes Barros, Thomas E. Wellems, Juliana M. Sá

Open Access Review

Transmission-blocking strategies: the roadmap from laboratory bench to the community

Daniel Gonçalves, Patrick Hunziker

Open Access Research

Plasmodium vivax mdr1 genotypes in isolates from successfully cured patients living in endemic and non-endemic Brazilian areas

Larissa Rodrigues Gomes, Natália Ketrin Almeida-de-Oliveira, Aline Rosa de Lavigne, Suelen Rezende Félix de Lima, Anielle de Pina-Costa, Patrícia Brasil, Cláudio Tadeu Daniel-Ribeiro, Didier Ménard, Maria de Fatima Ferreira-da-Cruz

Open Access Research

Tafenoquine treatment of Plasmodium vivax malaria: suggestive evidence that CYP2D6 reduced metabolism is not associated with relapse in the Phase 2b DETECTIVE trial

Pamela L. St Jean, Zhengyu Xue, Nick Carter, Gavin C. K. W. Koh, Stephan Duparc, Maxine Taylor, Claire Beaumont, Alejandro Llanos-Cuentas, Ronnatrai Rueangweerayut, Srivicha Krudsood, Justin A. Green, Justin P. Rubio

Open Access Research

Status of insecticide resistance in high-risk malaria provinces in Afghanistan

Mushtaq Ahmad, Cyril Buhler, Patricia Pignatelli, Hilary Ranson, Sami Mohammad Nahzat, Mohammad Naseem, Muhammad Farooq Sabawoon, Abdul Majeed Siddiqi, Martijn Vink

Open Access Review

The influence of pregnancy on the pharmacokinetic properties of artemisinin combination therapy (ACT): a systematic review

Renée J. Burger, Benjamin J. Visser, Martin P. Grobusch, Michèle van Vugt

Open Access Research

Incremental impact upon malaria transmission of supplementing pyrethroid-impregnated long-lasting insecticidal nets with indoor residual spraying using pyrethroids or the organophosphate, pirimiphos methyl

Busiku Hamainza, Chadwick H. Sikaala, Hawela B. Moonga, Javan Chanda, Dingani Chinula, Mulenga Mwenda, Mulakwa Kamuliwo, Adam Bennett, Aklilu Seyoum, Gerry F. Killeen

Open Access Research

Effectiveness of insecticidal nets on uncomplicated clinical malaria: a case–control study for operational evaluation

Georgia Barikissou Damien, Armel Djènontin, Evelyne Chaffa, Sandra Yamadjako, Papa Makhtar Drame, Emmanuel Elanga Ndille, Marie-Claire Henry, Vincent Corbel, Franck Remoué, Christophe Rogier

Open Access Research

An external sensing system in Plasmodium falciparum-infected erythrocytes

Yang Wu, Laura N. Cruz, Tadge Szestak, Gavin Laing, Gemma R. Molyneux, Celia R. S. Garcia, Alister G. Craig

Open Access Case Report

Imported Plasmodium vivax malaria with severe thrombocytopaenia: can it be severe malaria or not?

Spinello Antinori, Alberto Corona, Anna Lisa Ridolfo, Laura Galimberti, Davide Ricaboni, Laura Milazzo, Mario Corbellino

Open Access Research

A longitudinal study of the durability of long-lasting insecticidal nets in Zambia

Kathrine R. Tan, Jane Coleman, Barbara Smith, Busiku Hamainza, Cecilia Katebe-Sakala, Casey Kean, Ashley Kowal, Jodi Vanden Eng, Tiffany K. Parris, Carla T. Mapp, Stephen C. Smith, Robert Wirtz, Mulakwa Kamuliwo, Allen S. Craig

Open Access Research

Seeking treatment for uncomplicated malaria: experiences from the Kintampo districts of Ghana

Lawrence G. Febir, Kwaku Poku Asante, Samuel Afari-Asiedu, Livesy N. Abokyi, Anthony Kwarteng, Bernhards Ogutu, Margaret Gyapong, Seth Owusu-Agyei

Open Access Methodology

Simultaneous quantification of artesunate and mefloquine in fixed-dose combination tablets by multivariate calibration with middle infrared spectroscopy and partial least squares regression

Breno Maurício Marson, Raquel de Oliveira Vilhena, Camilla Regina de Souza Madeira, Flávia Lada Degaut Pontes, Mário Sérgio Piantavini, Roberto Pontarolo

Open Access Research

K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar

Aye A. Win, Mallika Imwong, Myat P. Kyaw, Charles J. Woodrow, Kesinee Chotivanich, Borimas Hanboonkunupakarn, Sasithon Pukrittayakamee

Open Access Research

Plasmodium falciparum ookinete expression of plasmepsin VII and plasmepsin X

Fengwu Li, Viengngeun Bounkeua, Kenneth Pettersen, Joseph M. Vinetz

Open Access Research

Application of magnetic cytosmear for the estimation of Plasmodium falciparum gametocyte density and detection of asexual stages in asymptomatic children

Deborah Sumari, Brian T. Grimberg, D’Arbra Blankenship, Joseph Mugasa, Kefas Mugittu, Lee Moore, Paul Gwakisa, Maciej Zborowski

Open Access Research

Small-scale land-use variability affects Anopheles spp. distribution and concomitant Plasmodium infection in humans and mosquito vectors in southeastern Madagascar

Sarah Zohdy, Kristin Derfus, Emily G. Headrick, Mbolatiana Tovo Andrianjafy, Patricia C. Wright, Thomas R. Gillespie

Open Access Research

Genotyping of Plasmodium vivax by minisatellite marker and its application in differentiating relapse and new infection

Ram Das, Ramesh C. Dhiman, Deepali Savargaonkar, Anupkumar R. Anvikar, Neena Valecha

Open Access Research

Biochemical and functional characterization of Plasmodium falciparum DNA polymerase δ

Jitlada Vasuvat, Atcha Montree, Sangduen Moonsom, Ubolsree Leartsakulpanich, Songsak Petmitr, Federico Focher, George E. Wright, Porntip Chavalitshewinkoon-Petmitr

Open Access Research

Assessment of the effectiveness of the CD3+ tool to detect counterfeit and substandard anti-malarials

JaCinta S. Batson, Daniel K. Bempong, Patrick H. Lukulay, Nicola Ranieri, R. Duane Satzger, Leigh Verbois

Open Access Meeting report

Establishing research priorities for malaria elimination in the context of the emergency response to artemisinin resistance framework-the Cambodian approach

Sara E. Canavati, Harriet L. S. Lawford, Bayo S. Fatunmbi, Dysoley Lek, Narann Top-Samphor, Rithea Leang, Arjen M. Dondorp, Rekol Huy, Walter M. Kazadi

Open Access Research

Clinical trials of artesunate plus sulfadoxine-pyrimethamine for Plasmodium falciparum malaria in Afghanistan: maintained efficacy a decade after introduction

Ghulam Rahim Awab, Mallika Imwong, Sasithon Pukrittayakamee, Fazel Alim, Warunee Hanpithakpong, Joel Tarning, Arjen M. Dondorp, Nicholas P. J. Day, Nicholas J. White, Charles J. Woodrow

Open Access Research

Exploring the spatiotemporal drivers of malaria elimination in Europe

Xia Zhao, David L. Smith, Andrew J. Tatem

Open Access Research

Antibody levels against GLURP R2, MSP1 block 2 hybrid and AS202.11 and the risk of malaria in children living in hyperendemic (Burkina Faso) and hypo-endemic (Ghana) areas

Bright Adu, Mariama K. Cherif, Samuel Bosomprah, Amidou Diarra, Fareed K. N. Arthur, Emmanuel K. Dickson, Giampietro Corradin, David R. Cavanagh, Michael Theisen, Sodiomon B. Sirima, Issa Nebie, Daniel Dodoo

Open Access Research

Anopheles subpictus carry human malaria parasites in an urban area of Western India and may facilitate perennial malaria transmission

Ashwani Kumar, Rajeshwari Hosmani, Shivaji Jadhav, Trelita de Sousa, Ajeet Mohanty, Milind Naik, Adarsh Shettigar, Satyajit Kale, Neena Valecha, Laura Chery, Pradipsinh K. Rathod

Open Access Research

Factors influencing adverse events reporting within the health care system: the case of artemisinin-based combination treatments in northern Ghana

Samuel Chatio, Raymond Aborigo, Philip Baba Adongo, Thomas Anyorigiya, Philip Ayizem Dalinjong, Patricia Akweongo, Abraham Oduro

Open Access Research

Challenges with implementing malaria rapid diagnostic tests at primary care facilities in a Ghanaian district: a qualitative study

Nana Yaa Boadu, John Amuasi, Daniel Ansong, Edna Einsiedel, Devidas Menon, Stephanie K. Yanow

Open Access Research

Bed net use among school-aged children after a universal bed net campaign in Malawi

Andrea G. Buchwald, Jenny A. Walldorf, Lauren M. Cohee, Jenna E. Coalson, Nelson Chimbiya, Andy Bauleni, Kondwani Nkanaunena, Andrew Ngwira, Atupele Kapito-Tembo, Don P. Mathanga, Terrie E. Taylor, Miriam K. Laufer

Open Access Methodology

Human malaria diagnosis using a single-step direct-PCR based on the Plasmodium cytochrome oxidase III gene

Diego F. Echeverry, Nicholas A. Deason, Jenna Davidson, Victoria Makuru, Honglin Xiao, Julie Niedbalski, Marcia Kern, Tanya L. Russell, Thomas R. Burkot, Frank H. Collins, Neil F. Lobo

Open Access Research

Population pharmacokinetics of a three-day chloroquine treatment in patients with Plasmodium vivax infection on the Thai-Myanmar border

Richard Höglund, Younis Moussavi, Ronnatrai Ruengweerayut, Anurak Cheomung, Angela Äbelö, Kesara Na-Bangchang

Open Access Research

Entomological aspects and the role of human behaviour in malaria transmission in a highland region of the Republic of Yemen

Samira M. A. Al-Eryani, Louise Kelly-Hope, Ralph E. Harbach, Andrew G. Briscoe, Guy Barnish, Ahmed Azazy, Philip J. McCall

Open Access Research

Operational challenges to continuous LLIN distribution: a qualitative rapid assessment in four countries

Katherine Theiss-Nyland, Waqo Ejersa, Corine Karema, Diakalia Koné, Hannah Koenker, Yves Cyaka, Matthew Lynch, Jayne Webster, Jo Lines

Open Access Research

Reactive case-detection of malaria in Pailin Province, Western Cambodia: lessons from a year-long evaluation in a pre-elimination setting

John Hustedt, Sara E. Canavati, Chandary Rang, Ruth A. Ashton, Nimol Khim, Laura Berne, Saorin Kim, Siv Sovannaroth, Po Ly, Didier Ménard, Jonathan Cox, Sylvia Meek, Arantxa Roca-Feltrer

Open Access Methodology

Multi-year optimization of malaria intervention: a mathematical model

Harry J. Dudley, Abhishek Goenka, Cesar J. Orellana, Susan E. Martonosi

Open Access Methodology

Development of insulated isothermal PCR for rapid on-site malaria detection

Kek Heng Chua, Ping Chin Lee, Hwa Chia Chai

Open Access Research

Spatially aggregated clusters and scattered smaller loci of elevated malaria vector density and human infection prevalence in urban Dar es Salaam, Tanzania

Victoria M. Mwakalinga, Benn K. D. Sartorius, Yeromin P. Mlacha, Daniel F. Msellemu, Alex J. Limwagu, Zawadi D. Mageni, John M. Paliga, Nicodem J. Govella, Maureen Coetzee, Gerry F. Killeen, Stefan Dongus

Open Access Research

Re-imagining adherence to treatment from the “other side”: local interpretations of adverse anti-malarial drug reactions in the Peruvian Amazon

Joan Muela Ribera, Susanna Hausmann-Muela, Charlotte Gryseels, Koen Peeters Grietens

Open Access Research

Analysis of ex vivo drug response data of Plasmodium clinical isolates: the pros and cons of different computer programs and online platforms

Grennady Wirjanata, Irene Handayuni, Sophie G. Zaloumis, Ferryanto Chalfein, Pak Prayoga, Enny Kenangalem, Jeanne Rini Poespoprodjo, Rintis Noviyanti, Julie A. Simpson, Ric N. Price, Jutta Marfurt

Open Access Research

Predicting factors for malaria re-introduction: an applied model in an elimination setting to prevent malaria outbreaks

Mansour Ranjbar, Alireza Shoghli, Goodarz Kolifarhood, Seyed Mehdi Tabatabaei, Morteza Amlashi, Mahdi Mohammadi

Open Access Research

B cell sub-types following acute malaria and associations with clinical immunity

Richard T. Sullivan, Isaac Ssewanyana, Samuel Wamala, Felistas Nankya, Prasanna Jagannathan, Jordan W. Tappero, Harriet Mayanja-Kizza, Mary K. Muhindo, Emmanuel Arinaitwe, Moses Kamya, Grant Dorsey, Margaret E. Feeney, Eleanor M. Riley, Chris J. Drakeley, Bryan Greenhouse

Open Access Research

Community point distribution of insecticide-treated bed nets and community health worker hang-up visits in rural Zambia: a decision-focused evaluation

Paul Wang, Alison L. Connor, Ammar S. Joudeh, Jeffrey Steinberg, Ketty Ndhlovu, Musanda Siyolwe, Bristol Ntebeka, Benjamin Chibuye, Busiku Hamainza

Open Access Research

Epidemiologic features of overseas imported malaria in the People's Republic of China

Zhongjie Li, Qian Zhang, Canjun Zheng, Sheng Zhou, Junling Sun, Zike Zhang, Qibin Geng, Honglong Zhang, Liping Wang, Shengjie Lai, Wenbiao Hu, Archie C. A. Clements, Xiao-Nong Zhou, Weizhong Yang

Open Access Research

Modelling the relative abundance of the primary African vectors of malaria before and after the implementation of indoor, insecticide-based vector control

Marianne E. Sinka, Nick Golding, N. Claire Massey, Antoinette Wiebe, Zhi Huang, Simon I. Hay, Catherine L. Moyes

Open Access Case study

Policy analysis for deciding on a malaria vaccine RTS,S in Tanzania

Idda Romore, Ritha J. A. Njau, Innocent Semali, Aziza Mwisongo, Antoinette Ba Nguz, Hassan Mshinda, Marcel Tanner, Salim Abdulla

Open Access Research

The risk of imported malaria in security forces personnel returning from overseas missions in the context of prevention of re-introduction of malaria to Sri Lanka

Sumadhya Deepika Fernando, Priyani Dharmawardana, Saveen Semege, Geetha Epasinghe, Niroshana Senanayake, Chaturaka Rodrigo, Risintha Premaratne

Open Access Research

Malaria incidence and entomological findings in an area targeted for a cluster-randomized controlled trial to prevent malaria in Ethiopia: results from a pilot study

Taye Gari, Oljira Kenea, Eskindir Loha, Wakgari Deressa, Alemayehu Hailu, Meshesha Balkew, Teshome Gebre-Michael, Bjarne Robberstad, Hans J. Overgaard, Bernt Lindtjørn

Open Access Methodology

New molecular settings to support in vivo anti-malarial assays

Noemí Bahamontes-Rosa, Ane Rodriguez Alejandre, Vanesa Gomez, Sara Viera, María G. Gomez-Lorenzo, Laura María Sanz-Alonso, Alfonso Mendoza-Losana

Open Access Research

Operational strategies of anti-malarial drug campaigns for malaria elimination in Zambia’s southern province: a simulation study

Erin M. Stuckey, John M. Miller, Megan Littrell, Nakul Chitnis, Rick Steketee

Open Access Review

Plasmodium falciparum: multifaceted resistance to artemisinins

Lucie Paloque, Arba P. Ramadani, Odile Mercereau-Puijalon, Jean-Michel Augereau, Françoise Benoit-Vical

Open Access Research

Expression of complement and toll-like receptor pathway genes is associated with malaria severity in Mali: a pilot case control study

Rafal S. Sobota, Antoine Dara, Jessica E. Manning, Amadou Niangaly, Jason A. Bailey, Abdoulaye K. Kone, Mahamadou A. Thera, Abdoulaye A. Djimdé, Guy Vernet, Philippe Leissner, Scott M. Williams, Christopher V. Plowe, Ogobara K. Doumbo

Open Access Research

Anopheles farauti is a homogeneous population that blood feeds early and outdoors in the Solomon Islands

Tanya L. Russell, Nigel W. Beebe, Hugo Bugoro, Allan Apairamo, Frank H. Collins, Robert D. Cooper, Neil F. Lobo, Thomas R. Burkot

Open Access Research

Determinants of host feeding success by Anopheles farauti

Tanya L. Russell, Nigel W. Beebe, Hugo Bugoro, Allan Apairamo, Robert D. Cooper, Frank H. Collins, Neil F. Lobo, Thomas R. Burkot

Open Access Research

Endogenously-expressed NH2-terminus of circumsporozoite protein interferes with sporozoite invasion of mosquito salivary glands

Bianca B. Kojin, André Luis Costa-da-Silva, Ceres Maciel, Dayane Alves Henriques, Danilo O. Carvalho, Kelcie Martin, Osvaldo Marinotti, Anthony A. James, Myrna C. Bonaldo, Margareth Lara Capurro

Open Access Methodology

A method to preserve low parasitaemia Plasmodium-infected avian blood for host and vector infectivity assays

Jenny S. Carlson, Federico Giannitti, Gediminas Valkiūnas, Lisa A. Tell, Joy Snipes, Stan Wright, Anthony J. Cornel

Open Access Research

Genetic diversity of Plasmodium falciparum isolates from concurrent malaria and arbovirus co-infections in Kedougou, southeastern Senegal

Makhtar Niang, Cheikh Loucoubar, Abdourahmane Sow, Moussa Moise Diagne, Oumar Faye, Ousmane Faye, Mawlouth Diallo, Aissatou Toure-Balde, Amadou A. Sall

Open Access Research

Frequent blood feeding enables insecticide-treated nets to reduce transmission by mosquitoes that bite predominately outdoors

Tanya L. Russell, Nigel W. Beebe, Hugo Bugoro, Allan Apairamo, Weng K. Chow, Robert D. Cooper, Frank H. Collins, Neil F. Lobo, Thomas R. Burkot

Open Access Research

Plasmodium falciparum parasitaemia and clinical malaria among school children living in a high transmission setting in western Kenya

Stella Kepha, Birgit Nikolay, Fred Nuwaha, Charles S. Mwandawiro, Joaniter Nankabirwa, Juliet Ndibazza, Jorge Cano, Damaris Matoke-Muhia, Rachel L. Pullan, Elizabeth Allen, Katherine E. Halliday, Simon J. Brooker

Open Access Research

“There is no free here, you have to pay”: actual and perceived costs as barriers to intermittent preventive treatment of malaria in pregnancy in Mali

Meredith C. Klein, Steven A. Harvey, Hawa Diarra, Emily A. Hurley, Namratha Rao, Samba Diop, Seydou Doumbia

Open Access Research

Immunogenicity of a chimeric Plasmodium falciparum merozoite surface protein vaccine in Aotus monkeys

James M. Burns Jr., Kazutoyo Miura, JoAnn Sullivan, Carole A. Long, John W. Barnwell

Open Access Research

The diagnostic accuracy of the hand-held Raman spectrometer for the identification of anti-malarial drugs

Benjamin J. Visser, Sophia G. de Vries, Emmanuel B. Bache, Janneke Meerveld-Gerrits, Daniëlle Kroon, Jimmy Boersma, Selidji T. Agnandji, Michèle van Vugt, Martin P. Grobusch

Open Access Research

Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA

Paola Favuzza, Simon Blaser, Anita M. Dreyer, Guy Riccio, Marco Tamborrini, Ralf Thoma, Hugues Matile, Gerd Pluschke

Open Access Research

Effect of mild medical hypothermia on in vitro growth of Plasmodium falciparum and the activity of anti-malarial drugs

Khalid Rehman, Ulrich Sauerzopf, Luzia Veletzky, Felix Lötsch, Mirjam Groger, Michael Ramharter

Open Access Research

Health workers’ compliance to rapid diagnostic tests (RDTs) to guide malaria treatment: a systematic review and meta-analysis

Alinune N. Kabaghe, Benjamin J. Visser, Rene Spijker, Kamija S. Phiri, Martin P. Grobusch, Michèle van Vugt

Open Access Research

Larval habitats of the Anopheles farauti and Anopheles lungae complexes in the Solomon Islands

Tanya L. Russell, Thomas R. Burkot, Hugo Bugoro, Allan Apairamo, Nigel W. Beebe, Weng K. Chow, Robert D. Cooper, Frank H. Collins, Neil F. Lobo

Open Access Methodology

Comparative performance of three experimental hut designs for measuring malaria vector responses to insecticides in Tanzania

Dennis J. Massue, William N. Kisinza, Bernard B. Malongo, Charles S. Mgaya, John Bradley, Jason D. Moore, Filemoni F. Tenu, Sarah J. Moore

Open Access Research

Does insecticide resistance contribute to heterogeneities in malaria transmission in The Gambia?

Kevin Ochieng’ Opondo, David Weetman, Musa Jawara, Mathurin Diatta, Amfaal Fofana, Florence Crombe, Julia Mwesigwa, Umberto D’Alessandro, Martin James Donnelly

Open Access Review

Tying malaria and microRNAs: from the biology to future diagnostic perspectives

Mercedes Rubio, Quique Bassat, Xavier Estivill, Alfredo Mayor

Open Access Research

Construction site workers’ malaria knowledge and treatment-seeking pattern in a highly endemic urban area of India

Siddharudha Shivalli, Sudarshan Pai, Kibballi Madhukeshwar Akshaya, Neevan D’Souza

Open Access Research

Reusing larval rearing water and its effect on development and quality of Anopheles arabiensis mosquitoes

Wadaka Mamai, Rosemary Susan Lees, Hamidou Maiga, Jeremie R. L. Gilles

Open Access Erratum

Erratum to: Imported malaria including HIV and pregnant woman risk groups: overview of the case of a Spanish city 2004–2014

María Fernández López, Jose Manuel Ruiz Giardín, Juan Víctor San Martín López, Jerónimo Jaquetti, Isabel García Arata, Carolina Jiménez Navarro, Noemi Cabello Clotet

Open Access Erratum

Erratum to: Synergistic anti-malarial action of cryptolepine and artemisinins

Arnold D. Forkuo, Charles Ansah, Kwesi M. Boadu, Johnson N. Boampong, Elvis O. Ameyaw, Ben A. Gyan, Andrea T. Arku, Michael F. Ofori

Open Access Research

Identification of Plasmodium falciparum specific translation inhibitors from the MMV Malaria Box using a high throughput in vitro translation screen

Vida Ahyong, Christine M. Sheridan, Kristoffer E. Leon, Jessica N. Witchley, Jonathan Diep, Joseph L. DeRisi

Open Access Research

Factors associated with malaria chemoprophylaxis compliance among French service members deployed in Central African Republic

Marie-Aude Créach, Guillaume Velut, Franck de Laval, Sébastien Briolant, Luc Aigle, Catherine Marimoutou, Xavier Deparis, Jean-Baptiste Meynard, Bruno Pradines, Fabrice Simon, Rémy Michel, Aurélie Mayet

Open Access Research

Low prevalence of Plasmodium and absence of malaria transmission in Conakry, Guinea: prospects for elimination

Bernard L. Kouassi, Dziedzom K. de Souza, Andre Goepogui, Siradiou M. Balde, Lamia Diakité, Arsène Sagno, Georgina I. Djameh, Frédérique Chammartin, Penelope Vounatsou, Moses J. Bockarie, Jürg Utzinger, Benjamin G. Koudou

Open Access Research

Durability of Olyset campaign nets distributed between 2009 and 2011 in eight districts of Tanzania

Dennis J. Massue, Sarah J. Moore, Zawadi D. Mageni, Jason D. Moore, John Bradley, Olivier Pigeon, Erasto J. Maziba, Renata Mandike, Karen Kramer, William N. Kisinza, Hans J. Overgaard, Lena M. Lorenz

Open Access Research

Feasibility, acceptability and impact of integrating malaria rapid diagnostic tests and pre-referral rectal artesunate into the integrated community case management programme. A pilot study in Mchinji district, Malawi

Themba B. Phiri, Blessings N. Kaunda-Khangamwa, Andrew Bauleni, Tiyese Chimuna, David Melody, Humphreys Kalengamaliro, John H. Sande, Humphreys Kampira Nsona, Don P. Mathanga

Open Access Research

Discovering the cost of care: consumer, provider, and retailer surveys shed light on the determinants of malaria health-seeking behaviours

Amruta Dixit, Ming-Chieh Lee, Brittany Goettsch, Yaw Afrane, Andrew K. Githeko, Guiyun Yan

Open Access Research

Development and evaluation of a spatial decision support system for malaria elimination in Bhutan

Kinley Wangdi, Cathy Banwell, Michelle L. Gatton, Gerard C. Kelly, Rinzin Namgay, Archie CA Clements

Open Access Research

Persistent Plasmodium falciparum and Plasmodium vivax infections in a western Cambodian population: implications for prevention, treatment and elimination strategies

Rupam Tripura, Thomas J. Peto, Jeremy Chalk, Sue J. Lee, Pasathorn Sirithiranont, Chea Nguon, Mehul Dhorda, Lorenz von Seidlein, Richard J. Maude, Nicholas P. J. Day, Mallika Imwong, Nicholas J. White, Arjen M. Dondorp

Open Access Research

Genomic signatures of population decline in the malaria mosquito Anopheles gambiae

Samantha M. O’Loughlin, Stephen M. Magesa, Charles Mbogo, Franklin Mosha, Janet Midega, Austin Burt

Open Access Reviewer Acknowledgement

Reviewer acknowledgement 2015

Marcel Hommel

Open Access Research

Cerebral malaria is associated with long-term mental health disorders: a cross sectional survey of a long-term cohort

Richard Idro, Angelina Kakooza-Mwesige, Benjamin Asea, Keron Ssebyala, Paul Bangirana, Robert O. Opoka, Samson K. Lubowa, Margaret Semrud-Clikeman, Chandy C. John, Joyce Nalugya

Open Access Research

Parasite clearance rates in Upper Myanmar indicate a distinctive artemisinin resistance phenotype: a therapeutic efficacy study

Kyaw Myo Tun, Atthanee Jeeyapant, Mallika Imwong, Min Thein, Sai Soe Moe Aung, Tin Maung Hlaing, Prayoon Yuentrakul, Cholrawee Promnarate, Mehul Dhorda, Charles J. Woodrow, Arjen M. Dondorp, Elizabeth A. Ashley, Frank M. Smithuis, Nicholas J. White, Nicholas P. J. Day

Open Access Research

Plasmodium falciparum chloroquine resistance transporter (PfCRT) isoforms PH1 and PH2 perturb vacuolar physiology

Paul S. Callaghan, Amila Siriwardana, Matthew R. Hassett, Paul D. Roepe

Open Access Research

Determinants of delay in malaria care-seeking behaviour for children 15 years and under in Bata district, Equatorial Guinea

Maria Romay-Barja, Jorge Cano, Policarpo Ncogo, Gloria Nseng, Maria A. Santana-Morales, Basilio Valladares, Matilde Riloha, Agustin Benito

Open Access Erratum

Erratum to: B cell sub-types following acute malaria and associations with clinical immunity

Richard T. Sullivan, Isaac Ssewanyana, Samuel Wamala, Felistas Nankya, Prasanna Jagannathan, Jordan W. Tappero, Harriet Mayanja-Kizza, Mary K. Muhindo, Emmanuel Arinaitwe, Moses Kamya, Grant Dorsey, Margaret E. Feeney, Eleanor M. Riley, Chris J. Drakeley, Bryan Greenhouse

Open Access Research

Stakeholders’ opinions and questions regarding the anticipated malaria vaccine in Tanzania

Sally Mtenga, Angela Kimweri, Idda Romore, Ali Ali, Amon Exavery, Elisa Sicuri, Marcel Tanner, Salim Abdulla, John Lusingu, Shubi Kafuruki

Open Access Research

Malaria vector populations across ecological zones in Guinea Conakry and Mali, West Africa

Boubacar Coulibaly, Raymond Kone, Mamadou S. Barry, Becky Emerson, Mamadou B. Coulibaly, Oumou Niare, Abdoul H. Beavogui, Sekou F. Traore, Kenneth D. Vernick, Michelle M. Riehle

Open Access Research

Behaviour and molecular identification of Anopheles malaria vectors in Jayapura district, Papua province, Indonesia

Brandy St. Laurent, Sukowati Supratman, Puji Budi Setia Asih, David Bretz, John Mueller, Helen Catherine Miller, Amirullah Baharuddin, Shinta, Asik Surya, Michelle Ngai, Ferdinand Laihad, Din Syafruddin, William A. Hawley, Frank H. Collins, Neil F. Lobo

Open Access Research

High heterogeneity of malaria transmission and a large sub-patent and diverse reservoir of infection in Wusab As Safil district, Republic of Yemen

Jackie Cook, Lynn Grignard, Samira Al-Eryani, Mustafa Al-Selwei, Abraham Mnzava, Hafed Al-Yarie, Alison Rand, Immo Kleinschmidt, Chris Drakeley

Open Access Research

Evidence of successful malaria case management policy implementation in Cambodia: results from national ACTwatch outlet surveys

Joe Novotny, Amandeep Singh, Lek Dysoley, Siv Sovannaroth, Huy Rekol

Open Access Research

‘Some anti-malarials are too strong for your body, they will harm you.’ Socio-cultural factors influencing pregnant women’s adherence to anti-malarial treatment in rural Gambia

Fatou Jaiteh, Susan Dierickx, Charlotte Gryseels, Sarah O’Neill, Umberto D’Alessandro, Susana Scott, Julie Balen, Koen Peeters Grietens

Open Access Research

Factors associated with the use of mosquito bed nets: results from two cross-sectional household surveys in Zambézia Province, Mozambique

Troy D. Moon, Caleb B. Hayes, Meridith Blevins, Melanie L. Lopez, Ann F. Green, Lazaro González-Calvo, Omo Olupona

Open Access Research

It could be viral but you don’t know, you have not diagnosed it: health worker challenges in managing non-malaria paediatric fevers in the low transmission area of Mbarara District, Uganda

Emily White Johansson, Freddy Eric Kitutu, Chrispus Mayora, Phyllis Awor, Stefan Swartling Peterson, Henry Wamani, Helena Hildenwall

Open Access Research

Early prediction of cerebral malaria by 1H NMR based metabolomics

Soumita Ghosh, Arjun Sengupta, Shobhona Sharma, Haripalsingh M. Sonawat

Open Access Research

Correlations between household occupancy and malaria vector biting risk in rural Tanzanian villages: implications for high-resolution spatial targeting of control interventions

Emmanuel W. Kaindoa, Gustav Mkandawile, Godfrey Ligamba, Louise A. Kelly-Hope, Fredros O. Okumu

Open Access Research

Key traveller groups of relevance to spatial malaria transmission: a survey of movement patterns in four sub-Saharan African countries

John M. Marshall, Mahamoudou Touré, André Lin Ouédraogo, Micky Ndhlovu, Samson S. Kiware, Ashley Rezai, Emmy Nkhama, Jamie T. Griffin, T. Deirdre Hollingsworth, Seydou Doumbia, Nicodem J. Govella, Neil M. Ferguson, Azra C. Ghani

Open Access Research

A highly infectious Plasmodium yoelii parasite, bearing Plasmodium falciparum circumsporozoite protein

Min Zhang, Izumi Kaneko, Tiffany Tsao, Robert Mitchell, Elizabeth H. Nardin, Shiroh Iwanaga, Masao Yuda, Moriya Tsuji

Open Access Research

Global genetic diversity of the Plasmodium vivax transmission-blocking vaccine candidate Pvs48/45

Andres F. Vallejo, Nora L. Martinez, Alejandra Tobon, Jackeline Alger, Marcus V. Lacerda, Andrey V. Kajava, Myriam Arévalo-Herrera, Sócrates Herrera

Open Access Research

Malaria in three epidemiological strata in Mauritania

Mohamed Ouldabdallahi Moukah, Ousmane Ba, Hampaté Ba, Mohamed Lemine Ould Khairy, Ousmane Faye, Hervé Bogreau, Frédéric Simard, Leonardo K. Basco

Open Access Research

Evidence of new species for malaria vector Anopheles nuneztovari sensu lato in the Brazilian Amazon region

Vera Margarete Scarpassa, Antonio Saulo Cunha-Machado, José Ferreira Saraiva

Open Access Research

Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes

Johann Beghain, Anne-Claire Langlois, Eric Legrand, Laura Grange, Nimol Khim, Benoit Witkowski, Valentine Duru, Laurence Ma, Christiane Bouchier, Didier Ménard, Richard E. Paul, Frédéric Ariey

Open Access Research

Identification of different malaria patterns due to Plasmodium falciparum and Plasmodium vivax in Ethiopian children: a prospective cohort study

Dinberu Seyoum, Yehenew Getachew Kifle, Virginie Rondeau, Delenasaw Yewhalaw, Luc Duchateau, Angel Rosas-Aguirre, Niko Speybroeck

Open Access Research

Assessment of the impact of the malaria elimination programme on the burden of disease morbidity in endemic areas of Iran

Khodadad Sheikhzadeh, Ali Akbar Haghdoost, Abbas Bahrampour, Farzaneh Zolala, Ahmad Raeisi

Open Access Research

Malaria illness mediated by anaemia lessens cognitive development in younger Ugandan children

Michael J. Boivin, Alla Sikorskii, Itziar Familiar-Lopez, Horacio Ruiseñor-Escudero, Mary Muhindo, James Kapisi, Victor Bigira, Judy K. Bass, Robert O. Opoka, Noeline Nakasujja, Moses Kamya, Grant Dorsey

Open Access Research

Perceptions and practices for preventing malaria in pregnancy in a peri-urban setting in south-western Uganda

Anthony K. Mbonye, Said M. Mohamud, James Bagonza

Open Access Research

Treatment and prevention of malaria in pregnancy in the private health sector in Uganda: implications for patient safety

Anthony K. Mbonye, Esther Buregyeya, Elizeus Rutebemberwa, Siân E. Clarke, Sham Lal, Kristian S. Hansen, Pascal Magnussen, Philip LaRussa

Open Access Research

Malaria hotspots defined by clinical malaria, asymptomatic carriage, PCR and vector numbers in a low transmission area on the Kenyan Coast

David Tiga Kangoye, Abdisalan Noor, Janet Midega, Joyce Mwongeli, Dora Mkabili, Polycarp Mogeni, Christine Kerubo, Pauline Akoo, Joseph Mwangangi, Chris Drakeley, Kevin Marsh, Philip Bejon, Patricia Njuguna

Open Access Case Study

Consolidating tactical planning and implementation frameworks for integrated vector management in Uganda

Michael Okia, Peter Okui, Myers Lugemwa, John M. Govere, Vincent Katamba, John B. Rwakimari, Betty Mpeka, Emmanuel Chanda

Open Access Methodology

Use of thin-layer chromatography to detect counterfeit sulfadoxine/pyrimethamine tablets with the wrong active ingredient in Malawi

Felix Khuluza, Stephen Kigera, Richard W. O. Jähnke, Lutz Heide

Open Access Research

The role of red blood cell exchange for severe imported malaria in the artesunate era: a retrospective cohort study in a referral centre

Antonia Calvo-Cano, Joan Gómez-Junyent, Miguel Lozano, Pedro Castro, Joan Cid, Jose María Nicolás, Llorenç Quintó, Maite Martin, Jose Muñoz, Joaquim Gascon

Open Access Research

Comparing ownership and use of bed nets at two sites with differential malaria transmission in western Kenya

Kacey C. Ernst, Mary H. Hayden, Heather Olsen, Jamie L. Cavanaugh, Irene Ruberto, Maurice Agawo, Stephen Munga

Open Access Case report

A zoonotic human infection with simian malaria, Plasmodium knowlesi, in Central Kalimantan, Indonesia

Wuryantari Setiadi, Herawati Sudoyo, Hidayat Trimarsanto, Boy Adventus Sihite, Riahdo Juliarman Saragih, Rita Juliawaty, Suradi Wangsamuda, Puji Budi Setia Asih, Din Syafruddin

Open Access Research

Seasonality and shift in age-specific malaria prevalence and incidence in Binko and Carrière villages close to the lake in Selingué, Mali

Mahamoudou Touré, Daouda Sanogo, Soumaila Dembele, Sory Ibrahima Diawara, Karen Oppfeldt, Karin L. Schiøler, Dade Ben Haidara, Sékou F. Traoré, Michael Alifrangis, Flemming Konradsen, Seydou Doumbia

Open Access Research

Ecological influences on the behaviour and fertility of malaria parasites

Lucy M. Carter, Laura C. Pollitt, Laurence G. Wilson, Sarah E. Reece

Open Access Research

Effectiveness of the delivery of interventions to prevent malaria in pregnancy in Kenya

Stephanie Dellicour, Jenny Hill, Jane Bruce, Peter Ouma, Doris Marwanga, Peter Otieno, Meghna Desai, Mary J. Hamel, Simon Kariuki, Jayne Webster

Open Access Methodology

ARAM: an automated image analysis software to determine rosetting parameters and parasitaemia in Plasmodium samples

Patrick Wolfgang Kudella, Kirsten Moll, Mats Wahlgren, Achim Wixforth, Christoph Westerhausen

Open Access Research

Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes

Pius S. Fasinu, Bharathi Avula, Babu L. Tekwani, N. P. Dhammika Nanayakkara, Yan-Hong Wang, H. M. T. Bandara Herath, James D. McChesney, Gregory A. Reichard, Sean R. Marcsisin, Mahmoud A. Elsohly, Shabana I. Khan, Ikhlas A. Khan, Larry A. Walker

Open Access Research

Most outdoor malaria transmission by behaviourally-resistant Anopheles arabiensis is mediated by mosquitoes that have previously been inside houses

Gerry F. Killeen, Nicodem J. Govella, Dickson W. Lwetoijera, Fredros O. Okumu

Open Access Research

Pre-infection administration of asiatic acid retards parasitaemia induction in Plasmodium berghei murine malaria infected Sprague-Dawley rats

Greanious Alfred Mavondo, Blessing Nkazimulo Mkhwananzi, Musa Vuyisile Mabandla

Open Access Research

Determinants of prompt and adequate care among presumed malaria cases in a community in eastern Rwanda: a cross sectional study

Chantal Marie Ingabire, Fredrick Kateera, Emmanuel Hakizimana, Alexis Rulisa, Claude Muvunyi, Petra Mens, Constantianus J. M. Koenraadt, Leon Mutesa, Michele Van Vugt, Bart Van Den Borne, Jane Alaii

Open Access Research

Genomic variation in two gametocyte non-producing Plasmodium falciparum clonal lines

Susana Campino, Ernest Diez Benavente, Samuel Assefa, Eloise Thompson, Laura G. Drought, Catherine J. Taylor, Zaria Gorvett, Celine K. Carret, Christian Flueck, Al C. Ivens, Dominic P. Kwiatkowski, Pietro Alano, David A. Baker, Taane G. Clark

Open Access Research

Chronic malaria and hyper-reactive malarial splenomegaly: a retrospective study on the largest series observed in a non-endemic country

Zeno Bisoffi, Stefania Leoni, Andrea Angheben, Anna Beltrame, Franklyn Esoka Eseme, Federico Gobbi, Claudia Lodesani, Stefania Marocco, Dora Buonfrate

Open Access Research

Enhanced transmission of malaria parasites to mosquitoes in a murine model of type 2 diabetes

Nazzy Pakpour, Kong Wai Cheung, Shirley Luckhart

Open Access Methodology

An ultrasensitive NanoLuc-based luminescence system for monitoring Plasmodium berghei throughout its life cycle

Mariana De Niz, Rebecca R. Stanway, Rahel Wacker, Derya Keller, Volker T. Heussler

Open Access Research

Visualization of house-entry behaviour of malaria mosquitoes

Jeroen Spitzen, Teun Koelewijn, W. Richard Mukabana, Willem Takken

Open Access Research

In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated Plasmodium falciparum malaria in Malawi, 2014

Magdalena Paczkowski, Dyson Mwandama, Daniel Marthey, Madalitso Luka, Georgina Makuta, John Sande, Doreen Ali, Peter Troell, Don P. Mathanga, Julie Gutman

Open Access Research

Malaria case clinical profiles and Plasmodium falciparum parasite genetic diversity: a cross sectional survey at two sites of different malaria transmission intensities in Rwanda

Fredrick Kateera, Sam L. Nsobya, Stephen Tukwasibwe, Petra F. Mens, Emmanuel Hakizimana, Martin P. Grobusch, Leon Mutesa, Nirbhay Kumar, Michele van Vugt

Open Access Research

Defining rules of CD8+ T cell expansion against pre-erythrocytic Plasmodium antigens in sporozoite-immunized mice

Zachary P. Billman, Arnold Kas, Brad C. Stone, Sean C. Murphy

Open Access Research

Increasing outdoor host-seeking in Anopheles gambiae over 6 years of vector control on Bioko Island

Jacob I. Meyers, Sharmila Pathikonda, Zachary R. Popkin-Hall, Matthew C. Medeiros, Godwin Fuseini, Abrahan Matias, Guillermo Garcia, Hans J. Overgaard, Vani Kulkarni, Vamsi P. Reddy, Christopher Schwabe, Jo Lines, Immo Kleinschmidt, Michel A. Slotman

Open Access Research

History of malaria treatment as a predictor of subsequent subclinical parasitaemia: a cross-sectional survey and malaria case records from three villages in Pailin, western Cambodia

Thomas J. Peto, Sabine E. Kloprogge, Rupam Tripura, Chea Nguon, Nou Sanann, Sovann Yok, Chhouen Heng, Cholrawee Promnarate, Jeremy Chalk, Ngak Song, Sue J. Lee, Yoel Lubell, Mehul Dhorda, Mallika Imwong, Nicholas J. White, Lorenz von Seidlein, Arjen Dondorp

Open Access Research

Determination of the foraging behaviour and blood meal source of malaria vector mosquitoes in Trincomalee District of Sri Lanka using a multiplex real time polymerase chain reaction assay

Nayana Gunathilaka, Thanuja Denipitiya, Menaka Hapugoda, Wimaladharma Abeyewickreme, Rajitha Wickremasinghe

Open Access Research

How important is the angle of tilt in the WHO cone bioassay?

Henry F. Owusu, Pie Müller

Open Access Research

Pharmacokinetic properties of intramuscular versus oral syrup paracetamol in Plasmodium falciparum malaria

Thanaporn Wattanakul, Pramote Teerapong, Katherine Plewes, Paul N. Newton, Wirongrong Chierakul, Kamolrat Silamut, Kesinee Chotivanich, Ronnatrai Ruengweerayut, Nicholas J. White, Arjen M. Dondorp, Joel Tarning

Open Access Research

Heterogeneous malaria transmission in long-term Afghan refugee populations: a cross-sectional study in five refugee camps in northern Pakistan

Sobia Wahid, Gillian H. Stresman, Syed Sajid Kamal, Nuno Sepulveda, Immo Kleinschmidt, Teun Bousema, Chris Drakeley

Open Access Research

Risk factors of malaria in children under the age of five years old in Uganda

Danielle Roberts, Glenda Matthews

Open Access Research

Monitoring iCCM referral systems: Bugoye Integrated Community Case Management Initiative (BIMI) in Uganda

Lacey English, James S. Miller, Rapheal Mbusa, Michael Matte, Jessica Kenney, Shem Bwambale, Moses Ntaro, Palka Patel, Edgar Mulogo, Geren S. Stone

Open Access Research

Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparum

Kossiwa Bandje, Bernina Naissant, Pascal Bigey, Murielle Lohezic, Marlène Vayssières, Magali Blaud, Laetitia Kermasson, José-Juan Lopez-Rubio, Gordon Langsley, Catherine Lavazec, Philippe Deloron, Anaïs Merckx

Open Access Research

Evaluation of intensified behaviour change communication strategies in an artemisinin resistance setting

Sara E. Canavati, Celine Zegers de Beyl, Po Ly, Muhammad Shafique, Thavrin Boukheng, Chandary Rang, Maxine Anne Whittaker, Arantxa Roca-Feltrer, David Sintasath

Open Access Research

Analysis of asymptomatic and clinical malaria in urban and suburban settings of southwestern Ethiopia in the context of sustaining malaria control and approaching elimination

Guofa Zhou, Delenasaw Yewhalaw, Eugenia Lo, Daibin Zhong, Xiaoming Wang, Teshome Degefa, Endalew Zemene, Ming-chieh Lee, Estifanos Kebede, Kora Tushune, Guiyun Yan

Open Access Research

Development of a Plasmodium berghei transgenic parasite expressing the full-length Plasmodium vivax circumsporozoite VK247 protein for testing vaccine efficacy in a murine model

Masanori Mizutani, Shinya Fukumoto, Adam Patrice Soubeiga, Akira Soga, Mitsuhiro Iyori, Shigeto Yoshida

Open Access Research

The importance of accounting for larval detectability in mosquito habitat-association studies

Matthew Low, Admasu Tassew Tsegaye, Rickard Ignell, Sharon Hill, Rasmus Elleby, Vilhelm Feltelius, Richard Hopkins

Open Access Research

Plasmodium falciparum malaria parasitaemia among indigenous Batwa and non-indigenous communities of Kanungu district, Uganda

Blánaid Donnelly, Lea Berrang-Ford, Jolène Labbé, Sabastian Twesigomwe, Shuaib Lwasa, Didacus B. Namanya, Sherilee L. Harper, Manisha Kulkarni, Nancy A. Ross, Pascal Michel

Open Access Research

Mortality and pathology in birds due to Plasmodium (Giovannolaia) homocircumflexum infection, with emphasis on the exoerythrocytic development of avian malaria parasites

Mikas Ilgūnas, Dovilė Bukauskaitė, Vaidas Palinauskas, Tatjana A. Iezhova, Nora Dinhopl, Nora Nedorost, Christiane Weissenbacher-Lang, Herbert Weissenböck, Gediminas Valkiūnas

Open Access Research

Assessing the effects of mosquito nets on malaria mortality using a space time model: a case study of Rufiji and Ifakara Health and Demographic Surveillance System sites in rural Tanzania

Majige Selemani, Amina S. Msengwa, Sigilbert Mrema, Amri Shamte, Michael J. Mahande, Karen Yeates, Maurice C. Y. Mbago, Angelina M. Lutambi

Open Access Research

Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria

Michael F. Duffy, Rintis Noviyanti, Takafumi Tsuboi, Zhi-Ping Feng, Leily Trianty, Boni F. Sebayang, Eizo Takashima, Fransisca Sumardy, Daniel A. Lampah, Louise Turner, Thomas Lavstsen, Freya J. I. Fowkes, Peter Siba, Stephen J. Rogerson, Thor G. Theander, Jutta Marfurt, Ric N. Price, Nicholas M. Anstey, Graham V. Brown, Anthony T. Papenfuss

Open Access Research

Distribution of malaria vectors and incidence of vivax malaria at Korean army installations near the demilitarized zone, Republic of Korea

Kyu Sik Chang, Dae-Hyun Yoo, Young Ran Ju, Wook Gyo Lee, Jong Yul Roh, Heung-Chul Kim, Terry A. Klein, E-Hyun Shin

Open Access Research

Cysteamine broadly improves the anti-plasmodial activity of artemisinins against murine blood stage and cerebral malaria

Neda Moradin, Sabrina Torre, Susan Gauthier, Mifong Tam, Jalal Hawari, Kirsten Vandercruyssen, Bart De Spiegeleer, Anny Fortin, Mary M. Stevenson, Philippe Gros

Open Access Research

Comparison of allele frequencies of Plasmodium falciparum merozoite antigens in malaria infections sampled in different years in a Kenyan population

Lynette Isabella Ochola-Oyier, John Okombo, Njoroge Wagatua, Jacob Ochieng, Kevin K. Tetteh, Greg Fegan, Philip Bejon, Kevin Marsh

Open Access Methodology

Benchmarking vector arthropod culture: an example using the African malaria mosquito, Anopheles gambiae (Diptera: Culicidae)

Laura Valerio, C. Matilda Collins, Rosemary Susan Lees, Mark Q. Benedict

Open Access Research

Insights into the Affordable Medicines Facility-malaria in Ghana: the role of caregivers and licensed chemical sellers in four regions

Andrew A. Adjei, Peter Winch, Amos Laar, David J. Sullivan Jr., Kwame S. Sakyi, Judith K. Stephens, George O. Adjei, Isaac A. Boateng, Vivian N. Ama Aubyn, Chrysantus Kubio, Julliette Tuakli, Linda Vanotoo, Bernard B. Bortei, Maame Amo-Addae, Felix Sorvor, Nathaniel Coleman, Sarah Dalglish, Richmond Owusu, Tsega Gebreyesus, Edward Essuman, Rebecca Greene, Ezekiel Ankomah, Kiely Houston, Constance Bart-Plange, Samuel Salamat, Ebenezer A. Addison, Isabella A. Quakyi

Open Access Research

Delayed acquisition of Plasmodium falciparum antigen-specific CD4+ T cell responses in HIV-exposed uninfected Malawian children receiving daily cotrimoxazole prophylaxis

Herbert Longwe, Kamija S. Phiri, Nyanyiwe M. Mbeye, Thandile Gondwe, Wilson L. Mandala, Kondwani C. Jambo

Open Access Research

Molecular mutation profile of pfcrt in Plasmodium falciparum isolates imported from Africa in Henan province

Rui-min Zhou, Hong-wei Zhang, Cheng-yun Yang, Ying Liu, Yu-ling Zhao, Su-hua Li, Dan Qian, Bian-li Xu

Open Access Research

Declining malaria transmission in rural Amazon: changing epidemiology and challenges to achieve elimination

Sheila Vitor-Silva, André Machado Siqueira, Vanderson de Souza Sampaio, Caterina Guinovart, Roberto Carlos Reyes-Lecca, Gisely Cardoso de Melo, Wuelton Marcelo Monteiro, Hernando A. del Portillo, Pedro Alonso, Quique Bassat, Marcus Vinícius Guimarães Lacerda

Open Access Research

Seroepidemiology of Plasmodium species infections in Zimbabwean population

Seth A. Amanfo, Takafira Mduluza, Nicholas Midzi, David R. Cavanagh, Francisca Mutapi

Open Access Research

Species composition and population dynamics of malaria vectors in three previously ignored aquatic systems in Sri Lanka

Achini W. Fernando, Sevvandi Jayakody, Hiranya K. Wijenayake, Gawrie N. L. Galappaththy, Mangala Yatawara, Jeevanie Harishchandra

Open Access Research

Clinical and epidemiological aspects of complicated malaria in Colombia, 2007–2013

Pablo E. Chaparro-Narváez, Mary Lopez-Perez, Lina Marcela Rengifo, Julio Padilla, Sócrates Herrera, Myriam Arévalo-Herrera

Open Access Research

Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum

Jin Zhang, John J. Bowling, David Smithson, Julie Clark, Melissa R. Jacob, Shabana I. Khan, Babu L. Tekwani, Michele Connelly, Vladimir Samoylenko, Mohamed A. Ibrahim, Mohamed A. Zaki, Mei Wang, John P. Hester, Ying Tu, Cynthia Jeffries, Nathaniel Twarog, Anang A. Shelat, Larry A. Walker, Ilias Muhammad, R. Kiplin Guy

Open Access Research

Targeting populations at higher risk for malaria: a survey of national malaria elimination programmes in the Asia Pacific

Shawn Wen, Kelly E. Harvard, Cara Smith Gueye, Sara E. Canavati, Arna Chancellor, Be-Nazir Ahmed, John Leaburi, Dysoley Lek, Rinzin Namgay, Asik Surya, Garib D. Thakur, Maxine Anne Whittaker, Roly D. Gosling

Open Access Research

Diagnosis of placental malaria in poorly fixed and processed placental tissue

Yunhao Liu, Jennifer B. Griffin, Atis Muehlenbachs, Stephen J. Rogerson, Anya J. Bailis, Rajni Sharma, David J. Sullivan, Antoinette K. Tshefu, Sarah H. Landis, Jean-Marie M. Kabongo, Steve M. Taylor, Steven R. Meshnick

Open Access Research

Census-derived migration data as a tool for informing malaria elimination policy

Nick W. Ruktanonchai, Darlene Bhavnani, Alessandro Sorichetta, Linus Bengtsson, Keith H. Carter, Roberto C. Córdoba, Arnaud Le Menach, Xin Lu, Erik Wetter, Elisabeth zu Erbach-Schoenberg, Andrew J. Tatem

Open Access Research

Overhead tank is the potential breeding habitat of Anopheles stephensi in an urban transmission setting of Chennai, India

Shalu Thomas, Sangamithra Ravishankaran, Johnson A. Justin, Aswin Asokan, Manu T. Mathai, Neena Valecha, Matthew B. Thomas, Alex Eapen

Open Access Research

Microsatellite genotyping and genome-wide single nucleotide polymorphism-based indices of Plasmodium falciparum diversity within clinical infections

Lee Murray, Victor A. Mobegi, Craig W. Duffy, Samuel A. Assefa, Dominic P. Kwiatkowski, Eugene Laman, Kovana M. Loua, David J. Conway

Open Access Research

Gravid Anopheles gambiae sensu stricto avoid ovipositing in Bermuda grass hay infusion and it’s volatiles in two choice egg-count bioassays

Lynda K. Eneh, Michael N. Okal, Anna-Karin Borg-Karlson, Ulrike Fillinger, Jenny M. Lindh

Open Access Research

Where chloroquine still works: the genetic make-up and susceptibility of Plasmodium vivax to chloroquine plus primaquine in Bhutan

Sonam Wangchuk, Tobgyel Drukpa, Kinley Penjor, Tashi Peldon, Yeshey Dorjey, Kunzang Dorji, Vishal Chhetri, Hidayat Trimarsanto, Sheren To, Amanda Murphy, Lorenz von Seidlein, Ric N. Price, Kamala Thriemer, Sarah Auburn

Open Access Research

Malaria prevalence, severity and treatment outcome in relation to day 7 lumefantrine plasma concentration in pregnant women

Ritah F. Mutagonda, Appolinary A. R. Kamuhabwa, Omary M. S. Minzi, Siriel N. Massawe, Betty A. Maganda, Eleni Aklillu

Open Access Research

Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail

Alexander Boes, Holger Spiegel, Robin Kastilan, Susanne Bethke, Nadja Voepel, Ivana Chudobová, Judith M. Bolscher, Koen J. Dechering, Rolf Fendel, Johannes F. Buyel, Andreas Reimann, Stefan Schillberg, Rainer Fischer

Open Access Research

Pre-clinical evaluation of CYP 2D6 dependent drug–drug interactions between primaquine and SSRI/SNRI antidepressants

Xiannu Jin, Brittney Potter, Thu-lan Luong, Jennifer Nelson, Chau Vuong, Corttney Potter, Lisa Xie, Jing Zhang, Ping Zhang, Jason Sousa, Qigui Li, Brandon S. Pybus, Mara Kreishman-Deitrick, Mark Hickman, Philip L. Smith, Robert Paris, Gregory Reichard, Sean R. Marcsisin

Open Access Research

Village malaria worker performance key to the elimination of artemisinin-resistant malaria: a Western Cambodia health system assessment

Sara E. Canavati, Saranath Lawpoolsri, Cesia E. Quintero, Chea Nguon, Po Ly, Sasithon Pukrittayakamee, David Sintasath, Pratap Singhasivanon, Koen Peeters Grietens, Maxine Anne Whittaker

Open Access Review

Challenges for malaria elimination in Brazil

Marcelo U. Ferreira, Marcia C. Castro

Open Access Research

High efficacy of artemether-lumefantrine and declining efficacy of artesunate + sulfadoxine-pyrimethamine against Plasmodium falciparum in Sudan (2010–2015): evidence from in vivo and molecular marker studies

Ahmed A. Adeel, Fahad Awad Ali Elnour, Khalid Abdalmutalab Elmardi, Mona B. Abd-Elmajid, Mai Mahmoud Elhelo, Mousab S. Ali, Mariam A. Adam, Hoda Atta, Ghasem Zamani, Marian Warsame, Amy Barrette, Hanan El Mohammady, Rania A. Nada

Open Access Research

Oral artemisinin monotherapy removal from the private sector in Eastern Myanmar between 2012 and 2014

Hnin Su Su Khin, Tin Aung, Aung Thi, Chris White

Open Access Research

The epidemiology of residual Plasmodium falciparum malaria transmission and infection burden in an African city with high coverage of multiple vector control measures

Daniel Msellemu, Hagai I. Namango, Victoria M. Mwakalinga, Alex J. Ntamatungiro, Yeromin Mlacha, Zacharia J. Mtema, Samson Kiware, Neil F. Lobo, Silas Majambere, Stefan Dongus, Christopher J. Drakeley, Nicodem J. Govella, Prosper P. Chaki, Gerry F. Killeen

Open Access Research

A significant association between deltamethrin resistance, Plasmodium falciparum infection and the Vgsc-1014S resistance mutation in Anopheles gambiae highlights the epidemiological importance of resistance markers

Bilali Kabula, Patrick Tungu, Emily J. Rippon, Keith Steen, William Kisinza, Stephen Magesa, Franklin Mosha, Martin James Donnelly

Open Access Research

Factors influencing choice of care-seeking for acute fever comparing private chemical shops with health centres and hospitals in Ghana: a study using case–control methodology

Evelyn K. Ansah, Margaret Gyapong, Solomon Narh-Bana, Constance Bart-Plange, Christopher J. M. Whitty

Open Access Research

Glucose-6-phosphate dehydrogenase deficiency prevalence and genetic variants in malaria endemic areas of Colombia

Sócrates Herrera Valencia, Iván Darío Ocampo, María Isabel Arce-Plata, Judith Recht, Myriam Arévalo-Herrera

Open Access Methodology

Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria

Caroline Pehrson, Line Mathiesen, Kristine K. Heno, Ali Salanti, Mafalda Resende, Ron Dzikowski, Peter Damm, Stefan R. Hansson, Christopher L. King, Henning Schneider, Christian W. Wang, Thomas Lavstsen, Thor G. Theander, Lisbeth E. Knudsen, Morten A. Nielsen

Open Access Research

First evaluation of bendiocarb in experimental huts using different substrates in Madagascar

Sanjiarizaha Randriamaherijaona, Thiery Nepomichene, Jade Assoukpa, Yoann Madec, Sébastien Boyer

Open Access Research

Malaria and other febrile diseases among travellers: the experience of a reference centre located outside the Brazilian Amazon Region

Andréa Beltrami Dotrário, Lucas José Bazzo Menon, Valdes Roberto Bollela, Roberto Martinez, Daniel Cardoso de Almeida e Araújo, Benedito Antônio Lopes da Fonseca, Rodrigo de C. Santana

Open Access Research

Sustained efficacy of artesunate-sulfadoxine-pyrimethamine against Plasmodium falciparum in Yemen and a renewed call for an adjunct single dose primaquine to clear gametocytes

Wahib M. Atroosh, Hesham M. Al-Mekhlafi, Georges Snounou, Adel Al-Jasari, Hany Sady, Nabil A. Nasr, Yee-Ling Lau, Johari Surin

Open Access Research

Asymptomatic Plasmodium infections in 18 villages of southern Savannakhet Province, Lao PDR (Laos)

Koukeo Phommasone, Bipin Adhikari, Gisela Henriques, Tiengkham Pongvongsa, Panom Phongmany, Lorenz von Seidlein, Nicholas J. White, Nicholas P. J. Day, Arjen M. Dondorp, Paul N. Newton, Mallika Imwong, Mayfong Mayxay

Open Access Erratum

Erratum to: K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar

Aye A. Win, Mallika Imwong, Myat P. Kyaw, Charles J. Woodrow, Kesinee Chotivanich, Borimas Hanboonkunupakarn, Sasithon Pukrittayakamee

Open Access Research

Encouraging impact following 2.5 years of reinforced malaria control interventions in a hyperendemic region of the Republic of Guinea

Amanda Tiffany, Faya Pascal Moundekeno, Alexis Traoré, Melat Haile, Esther Sterk, Timothée Guilavogui, Blaise Genton, Micaela Serafini, Rebecca F. Grais

Open Access Research

Detection of Plasmodium using filter paper and nested PCR for patients with malaria in Sanliurfa, in Turkey

Nebiye Yentur Doni, Fadile Yildiz Zeyrek, Adnan Seyrek

Open Access Case study

Strengthening individual capacity in monitoring and evaluation of malaria control programmes to streamline M&E systems and enhance information use in malaria endemic countries

Ashley Garley, Erin Eckert, Ali Sie, Maurice Ye, Keziah Malm, Edwin A. Afari, Mamadou Sawadogo, Samantha Herrera, Elizabeth Ivanovich, Yazoume Ye

Open Access Research

The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity

Sidhartha Chaudhury, Christian F. Ockenhouse, Jason A. Regules, Sheetij Dutta, Anders Wallqvist, Erik Jongert, Norman C. Waters, Franck Lemiale, Elke Bergmann-Leitner

Open Access Review

Combating poor-quality anti-malarial medicines: a call to action

Quique Bassat, Marcel Tanner, Philippe J. Guerin, Kirstin Stricker, Kamal Hamed

Open Access Commentary

World Malaria Day 2016 in the Kingdom of Cambodia: high-level governmental support embodies the WHO call for “political will to end malaria”

Sara E. Canavati, Cesia E. Quintero, Thavrin Bou, Virak Khieu, Rithea Leang, Dysoley Lek, Po Ly, Sinuon Muth, Kim Seng Lim, Luciano Tuseo, Sovann Yok, Kunthearith Yung, Jack S. Richards, Huy Rekol

Open Access Research

Severe anaemia associated with Plasmodium falciparum infection in children: consequences for additional blood sampling for research

Laura Maria Francisca Kuijpers, Jessica Maltha, Issa Guiraud, Bérenger Kaboré, Palpouguini Lompo, Hugo Devlieger, Chris Van Geet, Halidou Tinto, Jan Jacobs

Open Access Research

Mass testing and treatment for malaria in low transmission areas in Amhara Region, Ethiopia

Callie A. Scott, Asnakew K. Yeshiwondim, Belendia Serda, Caterina Guinovart, Berhane H. Tesfay, Adem Agmas, Melkamu T. Zeleke, Girma S. Guesses, Asmamaw L. Ayenew, Worku M. Workie, Richard W. Steketee, Duncan Earle, Belay Bezabih, Asefaw Getachew

Open Access Research

Immunogenetic markers associated with a naturally acquired humoral immune response against an N-terminal antigen of Plasmodium vivax merozoite surface protein 1 (PvMSP-1)

Gustavo Capatti Cassiano, Adriana A. C. Furini, Marcela P. Capobianco, Luciane M. Storti-Melo, Maria E. Almeida, Danielle R. L. Barbosa, Marinete M. Póvoa, Paulo A. Nogueira, Ricardo L. D. Machado

Open Access Research

Factors associated with high heterogeneity of malaria at fine spatial scale in the Western Kenyan highlands

Amrish Y. Baidjoe, Jennifer Stevenson, Philip Knight, William Stone, Gillian Stresman, Victor Osoti, Euniah Makori, Chrispin Owaga, Wycliffe Odongo, Pauline China, Shehu Shagari, Simon Kariuki, Chris Drakeley, Jonathan Cox, Teun Bousema

Open Access Research

Challenges encountered by local health volunteers in early diagnosis and prompt treatment of malaria in Myanmar artemisinin resistance containment zones

Myat Htut Nyunt, Khin Myo Aye, Khin Thiri Kyaw, Soe Soe Han, Thin Thin Aye, Khin Thet Wai, Myat Phone Kyaw

Open Access Research

Low-grade sulfadoxine–pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola

Elsa P. S. Kaingona-Daniel, Larissa Rodrigues Gomes, Bianca E. Gama, Natália K. Almeida-de-Oliveira, Filomeno Fortes, Didier Ménard, Cláudio Tadeu Daniel-Ribeiro, Maria de Fátima Ferreira-da-Cruz

Open Access Research

Sub-Saharan red cell antigen phenotypes and glucose-6-phosphate dehydrogenase deficiency variants in French Guiana

Florence Petit, Pascal Bailly, Jacques Chiaroni, Stéphane Mazières

Open Access Research

Experiences of households using integrated malaria prevention in two rural communities in Wakiso district, Uganda: a qualitative study

David Musoke, George Karani, Rawlance Ndejjo, Peter Okui, Miph Boses Musoke

Open Access Research

Ecology of urban malaria vectors in Niamey, Republic of Niger

Rabiou Labbo, Thierry Fandeur, Isabelle Jeanne, Cyril Czeher, Earle Williams, Ibrahim Arzika, Amadou Soumana, Ramatoulaye Lazoumar, Jean-Bernard Duchemin

Open Access Research

Prevalence of Plasmodium spp. in illegal gold miners in French Guiana in 2015: a hidden but critical malaria reservoir

Maylis Douine, Lise Musset, Florine Corlin, Stéphane Pelleau, Jérémie Pasquier, Louise Mutricy, Antoine Adenis, Felix Djossou, Paul Brousse, Frédérique Perotti, Helene Hiwat, Stephen Vreden, Magalie Demar, Mathieu Nacher

Open Access Research

Safety of a single low-dose of primaquine in addition to standard artemether-lumefantrine regimen for treatment of acute uncomplicated Plasmodium falciparum malaria in Tanzania

Richard Mwaiswelo, Billy E. Ngasala, Irina Jovel, Roland Gosling, Zul Premji, Eugenie Poirot, Bruno P. Mmbando, Anders Björkman, Andreas Mårtensson

Open Access Methodology

Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance

Daniela Kömpf, Jana Held, Stefani F. Müller, Hartmut R. Drechsel, Serena C. Tschan, Hinnak Northoff, Benjamin Mordmüller, Frank K. Gehring

Open Access Erratum

Erratum to: Epidemiologic features of overseas imported malaria in the People’s Republic of China

Zhongjie Li, Qian Zhang, Canjun Zheng, Sheng Zhou, Junling Sun, Zike Zhang, Qibin Geng, Honglong Zhang, Liping Wang, Shengjie Lai, Wenbiao Hu, Archie C. A. Clements, Xiao-Nong Zhou, Weizhong Yang

Open Access Research

Plasmodium falciparum parasite population structure and gene flow associated to anti-malarial drugs resistance in Cambodia

Ankit Dwivedi, Nimol Khim, Christelle Reynes, Patrice Ravel, Laurence Ma, Magali Tichit, Christiane Bourchier, Saorin Kim, Dany Dourng, Chanra Khean, Pheaktra Chim, Sovannaroth Siv, Roger Frutos, Dysoley Lek, Odile Mercereau-Puijalon, Frédéric Ariey, Didier Menard, Emmanuel Cornillot

Open Access Commentary

Building malaria out: improving health in the home

Lucy S. Tusting, Barbara Willey, Jo Lines

Open Access Research

Plasmodium vivax infection: a major determinant of severe anaemia in infancy

Enny Kenangalem, Muhammad Karyana, Lenny Burdarm, Shunmay Yeung, Julie A. Simpson, Emiliana Tjitra, Nicholas M. Anstey, Jeanne Rini Poespoprodjo, Ric N. Price, Nicholas M. Douglas

Open Access Research

Post-deployment effectiveness of malaria control interventions on Plasmodium infections in Madagascar: a comprehensive phase IV assessment

Thomas Kesteman, Milijaona Randrianarivelojosia, Patrice Piola, Christophe Rogier

Open Access Research

Plasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N-acylated adenylate kinase 2

Kazuo Ebine, Makoto Hirai, Miako Sakaguchi, Kazuhide Yahata, Osamu Kaneko, Yumiko Saito-Nakano

Open Access Research

Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions

Saul Lozano-Fuentes, Rebekah C. Kading, Daniel A. Hartman, Edward Okoth, Naftaly Githaka, Vishvanath Nene, Richard M. Poché

Open Access Research

Sharp increase of imported Plasmodium vivax malaria seen in migrants from Eritrea in Hamburg, Germany

Louise Roggelin, Dennis Tappe, Bernd Noack, Marylyn M. Addo, Egbert Tannich, Camilla Rothe

Open Access Research

Malaria prevention practices and delivery outcome: a cross sectional study of pregnant women attending a tertiary hospital in northeastern Nigeria

Hamzat U. Muhammad, Fatima J. Giwa, Adebola T. Olayinka, Shakir M. Balogun, IkeOluwapo Ajayi, Olufemi Ajumobi, Patrick Nguku

Open Access Research

Glucose-6-phosphate dehydrogenase deficiency among Yemeni children residing in malaria-endemic areas of Hodeidah governorate and evaluation of a rapid diagnostic test for its detection

Rashad Abdul-Ghani, Mohammed A. K. Mahdy, Reyadh Saif-Ali, Sameer A. Alkubati, Abdulhabib R. Alqubaty, Abdullah A. Al-Mikhlafy, Samira M. Al-Eryani, Abdusalam M. Al-Mekhlafi, Ali Alhaj

Open Access Research

Characterization of blood dendritic and regulatory T cells in asymptomatic adults with sub-microscopic Plasmodium falciparum or Plasmodium vivax infection

Steven Kho, Jutta Marfurt, Irene Handayuni, Zuleima Pava, Rintis Noviyanti, Andreas Kusuma, Kim A. Piera, Faustina H. Burdam, Enny Kenangalem, Daniel A. Lampah, Christian R. Engwerda, Jeanne R. Poespoprodjo, Ric N. Price, Nicholas M. Anstey, Gabriela Minigo, Tonia Woodberry

Open Access Research

Spatio-temporal variation and socio-demographic characters of malaria in Chimoio municipality, Mozambique

João Luís Ferrão, Jorge M. Mendes, Marco Painho, Sara Z. João

Open Access Research

Therapeutic efficacy trial of artemisinin-based combination therapy for the treatment of uncomplicated malaria and investigation of mutations in k13 propeller domain in Togo, 2012–2013

Améyo M. Dorkenoo, Degninou Yehadji, Yao M. Agbo, Yao Layibo, Foli Agbeko, Poukpessi Adjeloh, Kossi Yakpa, Efoe Sossou, Fantchè Awokou, Pascal Ringwald

Open Access Research

Common asymptomatic and submicroscopic malaria infections in Western Thailand revealed in longitudinal molecular and serological studies: a challenge to malaria elimination

Elisabeth Baum, Jetsumon Sattabongkot, Jeeraphat Sirichaisinthop, Kirakorn Kiattibutr, Aarti Jain, Omid Taghavian, Ming-Chieh Lee, D. Huw Davies, Liwang Cui, Philip L. Felgner, Guiyun Yan

Open Access Research

Who continues to stock oral artemisinin monotherapy? Results of a provider survey in Myanmar

Si Thu Thein, May Sudhinaraset, Hnin Su Su Khin, Willi McFarland, Tin Aung

Open Access Research

Molecular monitoring of Plasmodium falciparum super-resistance to sulfadoxine–pyrimethamine in Tanzania

Reginald A. Kavishe, Robert D. Kaaya, Sidsel Nag, Camilla Krogsgaard, Jakob Ginsbak Notland, Adellaida A. Kavishe, Deus Ishengoma, Cally Roper, Michael Alifrangis

Open Access Research

Mothers’ perception of recovery and satisfaction with patent medicine dealers’ treatment of childhood febrile conditions in rural communities

Georgian Chiaka Ibeneme, Ada Caroline Nwaneri, Sam Chidi Ibeneme, Pauline Ezenduka, Vanessa Strüver, Gehard Fortwengel, Ifeoma Joy Okoye

Open Access Research

Plasma levels of eight different mediators and their potential as biomarkers of various clinical malaria conditions in African children

Rachida Tahar, Catarina Albergaria, Neil Zeghidour, Vincent Foumane Ngane, Leonardo K. Basco, Christian Roussilhon

Open Access Research

Impact of using artemisinin-based combination therapy (ACT) in the treatment of uncomplicated malaria from Plasmodium falciparum in a non-endemic zone

Joaquín Pousibet-Puerto, Joaquín Salas-Coronas, Alicia Sánchez-Crespo, M. Angustias Molina-Arrebola, Manuel J. Soriano-Pérez, M. José Giménez-López, José Vázquez-Villegas, M. Teresa Cabezas-Fernández

Open Access Research

Integrated community case management and community-based health planning and services: a cross sectional study on the effectiveness of the national implementation for the treatment of malaria, diarrhoea and pneumonia

Blanca Escribano Ferrer, Jayne Webster, Jane Bruce, Solomon A. Narh- Bana, Clement T. Narh, Naa-KorKor Allotey, Roland Glover, Constance Bart-Plange, Isabella Sagoe-Moses, Keziah Malm, Margaret Gyapong

Open Access Research

Assessing supply-side barriers to uptake of intermittent preventive treatment for malaria in pregnancy: a qualitative study and document and record review in two regions of Uganda

Christian Rassi, Kirstie Graham, Patrobas Mufubenga, Rebecca King, Joslyn Meier, Sam Siduda Gudoi

Open Access Research

Factors associated with use of malaria control interventions by pregnant women in Buwunga subcounty, Bugiri District

Elizabeth Muhumuza, Noel Namuhani, Bonny Enock Balugaba, Jessica Namata, Elizabeth Ekirapa Kiracho

Open Access Erratum

Erratum to: Monitoring iCCM referral systems: Bugoye Integrated Community Case Management Initiative (BIMI) in Uganda

Lacey English, James S. Miller, Rapheal Mbusa, Michael Matte, Jessica Kenney, Shem Bwambale, Moses Ntaro, Palka Patel, Edgar Mulogo, Geren S. Stone

Open Access Research

OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimens

Ghaith Aljayyoussi, Katherine Kay, Stephen A. Ward, Giancarlo A. Biagini

Open Access Research

Spatial distribution estimation of malaria in northern China and its scenarios in 2020, 2030, 2040 and 2050

Yongze Song, Yong Ge, Jinfeng Wang, Zhoupeng Ren, Yilan Liao, Junhuan Peng

Open Access Research

Glucose-6-phosphate dehydrogenase deficiency and reduced haemoglobin levels in African children with severe malaria

Christian N. Nguetse, Christian G. Meyer, Ayola Akim Adegnika, Tsiri Agbenyega, Bernhards R. Ogutu, Peter G. Kremsner, Thirumalaisamy P. Velavan

Open Access Research

Prevalence of anti-malarial resistance genes in Dakar, Senegal from 2013 to 2014

Agathe Boussaroque, Bécaye Fall, Marylin Madamet, Khalifa Ababacar Wade, Mansour Fall, Aminata Nakoulima, Khadidiatou Ba Fall, Pierre Dionne, Nicolas Benoit, Bakary Diatta, Yaya Diemé, Boubacar Wade, Bruno Pradines

Open Access Erratum

Erratum to: Glucose-6-phosphate dehydrogenase deficiency prevalence and genetic variants in malaria endemic areas of Colombia

Sócrates Herrera Valencia, Iván Darío Ocampo, María Isabel Arce-Plata, Judith Recht, Myriam Arévalo-Herrera

Open Access Research

Geo-spatial factors associated with infection risk among young children in rural Ghana: a secondary spatial analysis

Ashley M. Aimone, Patrick E. Brown, Stanley H. Zlotkin, Donald C. Cole, Seth Owusu-Agyei

Open Access Research

Low prevalence of Plasmodium malariae and Plasmodium ovale mono-infections among children in the Democratic Republic of the Congo: a population-based, cross-sectional study

Stephanie M. Doctor, Yunhao Liu, Olivia G. Anderson, Amy N. Whitesell, Melchior Kashamuka Mwandagalirwa, Jérémie Muwonga, Corinna Keeler, Michael Emch, Joris L. Likwela, Antoinette Tshefu, Steven R. Meshnick

Open Access Research

Is Nigeria winning the battle against malaria? Prevalence, risk factors and KAP assessment among Hausa communities in Kano State

Salwa Dawaki, Hesham M. Al-Mekhlafi, Init Ithoi, Jamaiah Ibrahim, Wahib M. Atroosh, Awatif M. Abdulsalam, Hany Sady, Fatin Nur Elyana, Ado U. Adamu, Saadatu I. Yelwa, Abdulhamid Ahmed, Mona A. Al-Areeqi, Lahvanya R. Subramaniam, Nabil A. Nasr, Yee-Ling Lau

Open Access Research

Improved malaria case management in formal private sector through public private partnership in Ethiopia: retrospective descriptive study

Mesele D. Argaw, Asfawesen GY. Woldegiorgis, Derebe T. Abate, Mesfin E. Abebe

Open Access Research

Genetic diversity of Plasmodium falciparum in human malaria cases in Mali

Cécile Nabet, Safiatou Doumbo, Fakhri Jeddi, Salimata Konaté, Tommaso Manciulli, Bakary Fofana, Coralie L’Ollivier, Aminata Camara, Sandra Moore, Stéphane Ranque, Mahamadou A. Théra, Ogobara K. Doumbo, Renaud Piarroux

Open Access Research

Chicken volatiles repel host-seeking malaria mosquitoes

Kassahun T. Jaleta, Sharon Rose Hill, Göran Birgersson, Habte Tekie, Rickard Ignell

Open Access Research

Factors associated with the non-use of insecticide-treated nets in Rwandan children

Monique Murindahabi Ruyange, Jeanine Condo, Corine Karema, Agnes Binagwaho, Alphonse Rukundo, Yvette Muyirukazi

Open Access Research

‘Nature or nurture’: survival rate, oviposition interval, and possible gonotrophic discordance among South East Asian anophelines

J. Derek Charlwood, Somalay Nenhep, Siv Sovannaroth, John C. Morgan, Janet Hemingway, Nakul Chitnis, Olivier J. T. Briët

Open Access Case report

Transfusion-transmitted severe Plasmodium knowlesi malaria in a splenectomized patient with beta-thalassaemia major in Sabah, Malaysia: a case report

Elspeth M. Bird, Uma Parameswaran, Timothy William, Tien Meng Khoo, Matthew J. Grigg, Ammar Aziz, Jutta Marfurt, Tsin W. Yeo, Sarah Auburn, Nicholas M. Anstey, Bridget E. Barber

Open Access Review

The development of malaria diagnostic techniques: a review of the approaches with focus on dielectrophoretic and magnetophoretic methods

Surasak Kasetsirikul, Jirayut Buranapong, Werayut Srituravanich, Morakot Kaewthamasorn, Alongkorn Pimpin

Open Access Research

A cross-sectional study of the availability and price of anti-malarial medicines and malaria rapid diagnostic tests in private sector retail drug outlets in rural Western Kenya, 2013

Urbanus Kioko, Christina Riley, Stephanie Dellicour, Vincent Were, Peter Ouma, Julie Gutman, Simon Kariuki, Ahmeddin Omar, Meghna Desai, Ann M. Buff

Open Access Review

A review of new challenges and prospects for malaria elimination in Mutare and Mutasa Districts, Zimbabwe

Shadreck Sande, Moses Zimba, Peter Chinwada, Hieronymo Takundwa Masendu, Joseph Mberikunshe, Aramu Makuwaza

Open Access Research

Longitudinal effect of CD4 by cotrimoxazole use on malaria incidence among HIV-infected Ugandan adults on antiretroviral therapy: a randomized controlled study

Ronnie Kasirye, Heiner Grosskurth, Paula Munderi, Jonathan Levin, Zacchaeus Anywaine, Andrew Nunn, Anatoli Kamali, Kathy Baisley

Open Access Research

Identifying risk factors for Plasmodium infection and anaemia in Kinshasa, Democratic Republic of Congo

Giovanfrancesco Ferrari, Henry M. T. Ntuku, Amanda Ross, Sandro Schmidlin, Didier M. Kalemwa, Antoinette K. Tshefu, Christian Lengeler

Open Access Research

Modelling the influence of temperature and rainfall on the population dynamics of Anopheles arabiensis

Gbenga J. Abiodun, Rajendra Maharaj, Peter Witbooi, Kazeem O. Okosun

Open Access Review

The role of early detection and treatment in malaria elimination

Jordi Landier, Daniel M. Parker, Aung Myint Thu, Verena I. Carrara, Khin Maung Lwin, Craig A. Bonnington, Sasithon Pukrittayakamee, Gilles Delmas, François H. Nosten

Open Access Research

The production and exportation of artemisinin-derived drugs in China: current status and existing challenges

Yangmu Huang, Hui Li, Danlu Peng, Yu Wang, Qiaomeng Ren, Yan Guo

Open Access Research

Equity in long-lasting insecticidal nets and indoor residual spraying for malaria prevention in a rural South Central Ethiopia

Alemayehu Hailu, Bernt Lindtjørn, Wakgari Deressa, Taye Gari, Eskindir Loha, Bjarne Robberstad

Open Access Research

Cost-effectiveness of seasonal malaria chemoprevention in upper west region of Ghana

Justice Nonvignon, Genevieve Cecilia Aryeetey, Shamwill Issah, Patrick Ansah, Keziah L. Malm, Winfred Ofosu, Titus Tagoe, Samuel Agyei Agyemang, Moses Aikins

Open Access Research

Adherence to national guidelines for the diagnosis and management of severe malaria: a nationwide, cross-sectional survey in Malawi, 2012

Monica P. Shah, Melissa Briggs-Hagen, Jobiba Chinkhumba, Andy Bauleni, Alfred Chalira, Dubulao Moyo, Wilfred Dodoli, Misheck Luhanga, John Sande, Doreen Ali, Julie Gutman, Don P. Mathanga, Kim A. Lindblade

Open Access Research

Vertical stratification of adult mosquitoes (Diptera: Culicidae) within a tropical rainforest in Sabah, Malaysia

Hayley L. Brant, Robert M. Ewers, Indra Vythilingam, Chris Drakeley, Suzan Benedick, John D. Mumford

Open Access Research

Evaluation of the paediatric dose of chloroquine in the treatment of Plasmodium vivax malaria

Arletta Añez, Manuel Moscoso, Cecilia Garnica, Carlos Ascaso

Open Access Research

Determinants of public malaria awareness during the national malaria elimination programme: a cross-sectional study in rural China

Shangfeng Tang, Lu Ji, Tao Hu, Ghose Bishwajit, Da Feng, Hui Ming, Yue Xian, Qian Fu, Zhifei He, Hang Fu, Ruoxi Wang, Zhanchun Feng

Open Access Research

Public awareness of malaria in the middle stage of national malaria elimination programme. A cross-sectional survey in rural areas of malaria-endemic counties, China

Shangfeng Tang, Lu Ji, Tao Hu, Ruoxi Wang, Hang Fu, Tian Shao, Chunyan Liu, Piaopiao Shao, Zhe He, Gang Li, Zhanchun Feng

Open Access Research

Cytokine gene polymorphisms are not associated with anti-PvDBP, anti-PvAMA-1 or anti-PvMSP-119 IgG antibody levels in a malaria-endemic area of the Brazilian Amazon

Adriana A. C. Furini, Marcela P. Capobianco, Luciane M. Storti-Melo, Maristela G. Cunha, Gustavo C. Cassiano, Ricardo Luiz D. Machado

Open Access Research

An experimental hut evaluation of Olyset Plus, a long-lasting insecticidal net treated with a mixture of permethrin and piperonyl butoxide, against Anopheles fluviatilis in Odisha State, India

Kasinathan Gunasekaran, Sudhansu Sekhar Sahu, Tharmalingam Vijayakumar, Swaminathan Subramanian, Rajpal Singh Yadav, Olivier Pigeon, Purushothaman Jambulingam

Open Access Review

Malaria vector research and control in Haiti: a systematic review

Joseph Frederick, Yvan Saint Jean, Jean Frantz Lemoine, Ellen M. Dotson, Kimberly E. Mace, Michelle Chang, Laurence Slutsker, Arnaud Le Menach, John C. Beier, Thomas P. Eisele, Bernard A. Okech, Valery Madsen Beau de Rochars, Keith H. Carter, Joseph Keating, Daniel E. Impoinvil

Open Access Research

Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity

Bradley W. Hickey, Joanne M. Lumsden, Sharina Reyes, Martha Sedegah, Michael R. Hollingdale, Daniel A. Freilich, Thomas C. Luke, Yupin Charoenvit, Lucy M. Goh, Mara P. Berzins, Lolita Bebris, John B. Sacci Jr., Patricia De La Vega, Ruobing Wang, Harini Ganeshan, Esteban N. Abot, Daniel J. Carucci, Denise L. Doolan, Gary T. Brice, Anita Kumar, Joao Aguiar, Thomas B. Nutman, Susan F. Leitman, Stephen L. Hoffman, Judith E. Epstein, Thomas L. Richie

Open Access Research

A cluster randomized trial comparing deltamethrin and bendiocarb as insecticides for indoor residual spraying to control malaria on Bioko Island, Equatorial Guinea

John Bradley, Dianna Hergott, Guillermo Garcia, Jo Lines, Jackie Cook, Michel A. Slotman, Wonder Philip Phiri, Christopher Schwabe, Immo Kleinschmidt

Open Access Research

Prenatal exposure to Plasmodium falciparum increases frequency and shortens time from birth to first clinical malaria episodes during the first two years of life: prospective birth cohort study

Boniphace Sylvester, Dinah B. Gasarasi, Said Aboud, Donath Tarimo, Siriel Massawe, Rose Mpembeni, Gote Swedberg

Open Access Research

Routine implementation costs of larviciding with Bacillus thuringiensis israelensis against malaria vectors in a district in rural Burkina Faso

Peter Dambach, Michael Schleicher, Hans-Christian Stahl, Issouf Traoré, Norbert Becker, Achim Kaiser, Ali Sié, Rainer Sauerborn

Open Access Research

In vitro selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemisinin

Muturi J. Njokah, Joseph N. Kang’ethe, Johnson Kinyua, Daniel Kariuki, Francis T. Kimani

Open Access Research

Anti-malarial seroprevalence assessment during an elimination programme in Chabahar District, south-eastern Iran

Sedigheh Zakeri, Lotus Leonie van den Hoogen, Akram Abouie Mehrizi, Fatemh Karimi, Ahmad Raeisi, Chris Drakeley

Open Access Research

Development of a pharmacovigilance safety monitoring tool for the rollout of single low-dose primaquine and artemether-lumefantrine to treat Plasmodium falciparum infections in Swaziland: a pilot study

Eugenie Poirot, Adam Soble, Nyasatu Ntshalintshali, Asen Mwandemele, Nomcebo Mkhonta, Calisile Malambe, Sibonakaliso Vilakati, Sisi Pan, Sarah Darteh, Gugu Maphalala, Joelle Brown, Jimee Hwang, Cheryl Pace, Andy Stergachis, Eric Vittinghoff, Simon Kunene, Roland Gosling

Open Access Research

A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents

Noemí Bahamontes-Rosa, María G. Gomez-Lorenzo, Joël Lelièvre, Ane Rodriguez Alejandre, María Jesus Almela, Sonia Lozano, Esperanza Herreros, Francisco-Javier Gamo

Open Access Research

Composition and genetics of malaria vector populations in the Central African Republic

Mamadou Ousmane Ndiath, Karin Eiglmeier, Marina Lidwine Olé Sangba, Inge Holm, Mirdad Kazanji, Kenneth D. Vernick

Open Access Research

Prevalence of G6PD deficiency and Plasmodium falciparum parasites in asymptomatic school children living in southern Ghana

Linda Eva Amoah, Akua Opong, Ruth Ayanful-Torgby, Joana Abankwa, Festus K. Acquah

Open Access Research

Performance of rapid diagnostic test, blood-film microscopy and PCR for the diagnosis of malaria infection among febrile children from Korogwe District, Tanzania

Coline Mahende, Billy Ngasala, John Lusingu, Tai-Soon Yong, Paminus Lushino, Martha Lemnge, Bruno Mmbando, Zul Premji

Open Access Research

Pregnant women and infants as sentinel populations to monitor prevalence of malaria: results of pilot study in Lake Zone of Tanzania

Ritha A. Willilo, Fabrizio Molteni, Renata Mandike, Frances E. Mugalura, Anold Mutafungwa, Adella Thadeo, Edwin Benedictor, Jessica M. Kafuko, Naomi Kaspar, Mahdi M. Ramsan, Osia Mwaipape, Peter D. McElroy, Julie Gutman, Rajeev Colaco, Richard Reithinger, Jeremiah M. Ngondi

Open Access Research

Integrin αDβ2 (CD11d/CD18) mediates experimental malaria-associated acute respiratory distress syndrome (MA-ARDS)

Isaclaudia G. de Azevedo-Quintanilha, Adriana Vieira-de-Abreu, André Costa Ferreira, Daniele O. Nascimento, Alessandra M. Siqueira, Robert A. Campbell, Tatiana P. Teixeira Ferreira, Tatiana M. Gutierrez, Gabriel M. Ribeiro, Patricia M. R. e Silva, Alysson R. Carvalho, Patricia T. Bozza, Guy A. Zimmerman, Hugo C. Castro-Faria-Neto

Open Access Research

Species-specific escape of Plasmodium sporozoites from oocysts of avian, rodent, and human malarial parasites

Alessandra S. Orfano, Rafael Nacif-Pimenta, Ana P. M. Duarte, Luis M. Villegas, Nilton B. Rodrigues, Luciana C. Pinto, Keillen M. M. Campos, Yudi T. Pinilla, Bárbara Chaves, Maria G. V. Barbosa Guerra, Wuelton M. Monteiro, Ryan C. Smith, Alvaro Molina-Cruz, Marcus V. G. Lacerda, Nágila F. C. Secundino, Marcelo Jacobs-Lorena, Carolina Barillas-Mury, Paulo F. P. Pimenta

Open Access Research

Integrated paediatric fever management and antibiotic over-treatment in Malawi health facilities: data mining a national facility census

Emily White Johansson, Katarina Ekholm Selling, Humphreys Nsona, Bonnie Mappin, Peter W. Gething, Max Petzold, Stefan Swartling Peterson, Helena Hildenwall

Open Access Research

Anti-erythrocyte antibodies may contribute to anaemia in Plasmodium vivax malaria by decreasing red blood cell deformability and increasing erythrophagocytosis

Luiza Carvalho Mourão, Paula Magda da Silva Roma, Jamila da Silva Sultane Aboobacar, Camila Maia Pantuzzo Medeiros, Zélia Barbosa de Almeida, Cor Jesus Fernandes Fontes, Ubirajara Agero, Oscar Nassif de Mesquita, Marcelo Porto Bemquerer, Érika Martins Braga

Open Access Research

Diagnosis and treatment based on quantitative PCR after controlled human malaria infection

Jona Walk, Remko Schats, Marijke C. C. Langenberg, Isaie J. Reuling, Karina Teelen, Meta Roestenberg, Cornelus C. Hermsen, Leo G. Visser, Robert W. Sauerwein

Open Access Methodology

Direct transfer of HRPII-magnetic bead complexes to malaria rapid diagnostic tests significantly improves test sensitivity

Keersten M. Ricks, Nicholas M. Adams, Thomas F. Scherr, Frederick R. Haselton, David W. Wright

Open Access Research

A qualitative review of implementer perceptions of the national community-level malaria surveillance system in Southern Province, Zambia

Lynne Lohfeld, Tokozile Kangombe-Ngwenya, Anna M. Winters, Zunda Chisha, Busiku Hamainza, Mulakwa Kamuliwo, John M. Miller, Matthew Burns, Daniel J. Bridges

Open Access Research

The challenge of using intermittent preventive therapy with sulfadoxine/pyrimethamine among pregnant women in Uganda

Humphrey Wanzira, Henry Katamba, Allen Eva Okullo, Denis Rubahika

Open Access Research

A comparison of malaria prevalence, control and management strategies in irrigated and non-irrigated areas in eastern Kenya

John Muthii Muriuki, Philip Kitala, Gerald Muchemi, Ian Njeru, Joan Karanja, Bernard Bett

Open Access Research

Plasma levels of Galectin-9 reflect disease severity in malaria infection

Bindongo P. P. Dembele, Haorile Chagan-Yasutan, Toshiro Niki, Yugo Ashino, Noppadon Tangpukdee, Egawa Shinichi, Srivicha Krudsood, Shigeyuki Kano, Toshio Hattori

Open Access Commentary

Eave tubes for malaria control in Africa: an introduction

Bart G. J. Knols, Marit Farenhorst, Rob Andriessen, Janneke Snetselaar, Remco A. Suer, Anne J. Osinga, Johan M. H. Knols, Johan Deschietere, Kija R. Ng’habi, Issa N. Lyimo, Stella T. Kessy, Valeriana S. Mayagaya, Sergej Sperling, Michael Cordel, Eleanore D. Sternberg, Patrick Hartmann, Ladslaus L. Mnyone, Andreas Rose, Matthew B. Thomas

Open Access Research

Assessment of Pfs25 expressed from multiple soluble expression platforms for use as transmission-blocking vaccine candidates

Shwu-Maan Lee, Chia-Kuei Wu, Jordan Plieskatt, David H. McAdams, Kazutoyo Miura, Chris Ockenhouse, C. Richter King

Open Access Commentary

Development of new malaria diagnostics: matching performance and need

David Bell, Alessandra E. Fleurent, Michael C. Hegg, John D. Boomgard, Caitlin C. McConnico

Open Access Research

Spatial distributions of Anopheles species in relation to malaria incidence at 70 localities in the highly endemic Northwest and South Pacific coast regions of Colombia

Martha L. Ahumada, Lorena I. Orjuela, Paula X. Pareja, Marcela Conde, Diana M. Cabarcas, Eliana F. G. Cubillos, Jorge A. Lopez, John C. Beier, Sócrates Herrera, Martha L. Quiñones

Open Access Methodology

A framework for evaluating the costs of malaria elimination interventions: an application to reactive case detection in Southern Province of Zambia, 2014

Bruce A. Larson, Thandiwe Ngoma, Kafula Silumbe, Marie-Reine I. Rutagwera, Busiku Hamainza, Anna M. Winters, John M. Miller, Callie A. Scott

Open Access Research

Sustaining control: lessons from the Lubombo spatial development initiative in southern Africa

Rajendra Maharaj, Devanand Moonasar, Candrinho Baltazar, Simon Kunene, Natashia Morris

Open Access Research

Quantifying the removal of red blood cells in Macaca mulatta during a Plasmodium coatneyi infection

Luis L. Fonseca, Harnel S. Alezi, Alberto Moreno, John W. Barnwell, Mary R. Galinski, Eberhard O. Voit

Open Access Research

Diversity and frequency of kdr mutations within Anopheles sinensis populations from Guangxi, China

Chan Yang, Xiangyang Feng, Zushi Huang, Mei Li, Xinghui Qiu

Open Access Research

Evaluation of the operational challenges in implementing reactive screen-and-treat and implications of reactive case detection strategies for malaria elimination in a region of low transmission in southern Zambia

Kelly M. Searle, Harry Hamapumbu, Jailos Lubinda, Timothy M. Shields, Jessie Pinchoff, Tamaki Kobayashi, Jennifer C. Stevenson, Daniel J. Bridges, David A. Larsen, Philip E. Thuma, William J. Moss

Open Access Research

Feasibility and implementation of community-based malaria case management with integrated vector control in the Democratic Republic of Congo

Edouard Kawawa Swana, Ghislain Yav Makan, Clarence Kaut Mukeng, Henriette Ilunga Mupumba, Gabriel Mutabusha Kalaba, Oscar Numbi Luboya, Michael J. Bangs

Open Access Research

Prevalence of crt and mdr-1 mutations in Plasmodium falciparum isolates from Grande Comore island after withdrawal of chloroquine

Bo Huang, Qi Wang, Changsheng Deng, Jianhua Wang, Tao Yang, Shiguang Huang, Xin-zhuan Su, Yajun Liu, Longhua Pan, Guoming Li, Di Li, Hongying Zhang, Afane Bacar, Kamal Said Abdallah, Rachad Attoumane, Ahamada M. S. A. Mliva, Shaoqin Zheng, Qin Xu, Fangli Lu, Yezhi Guan, Jianping Song

Open Access Erratum

Erratum to: Construction site workers’ malaria knowledge and treatment-seeking pattern in a highly endemic urban area of India

Siddharudha Shivalli, Sudarshan Pai, Kibballi Madhukeshwar Akshaya, Neevan D’Souza

Open Access Research

Phagocytosis-inducing antibodies to Plasmodium falciparum upon immunization with a recombinant PfEMP1 NTS-DBL1α domain

Maria del Pilar Quintana, Davide Angeletti, Kirsten Moll, Qijun Chen, Mats Wahlgren

Open Access Research

Malaria intervention scale-up in Africa: effectiveness predictions for health programme planning tools, based on dynamic transmission modelling

Eline Korenromp, Guy Mahiané, Matthew Hamilton, Carel Pretorius, Richard Cibulskis, Jeremy Lauer, Thomas A. Smith, Olivier J. T. Briët

Open Access Case study

Using supply side evidence to inform oral artemisinin monotherapy replacement in Myanmar: a case study

Hnin Su Su Khin, Tin Aung, Moe Aung, Aung Thi, Matt Boxshall, Chris White

Open Access Commentary

Towards malaria elimination in the MOSASWA (Mozambique, South Africa and Swaziland) region

Devanand Moonasar, Rajendra Maharaj, Simon Kunene, Baltazar Candrinho, Francisco Saute, Nyasatu Ntshalintshali, Natashia Morris

Open Access Research

Malaria in urban, semi-urban and rural areas of southern of Gabon: comparison of the Pfmdr 1 and Pfcrt genotypes from symptomatic children

Sydney Maghendji-Nzondo, Lady-Charlène Kouna, Gaël Mourembou, Larson Boundenga, Romeo-Karl Imboumy-Limoukou, Pierre-Blaise Matsiegui, Rella Manego-Zoleko, Bertrand Mbatchi, Didier Raoult, Fousseyni Toure-Ndouo, Jean Bernard Lekana-Douki

Open Access Research

Assessment of submicroscopic infections and gametocyte carriage of Plasmodium falciparum during peak malaria transmission season in a community-based cross-sectional survey in western Kenya, 2012

Zhiyong Zhou, Rebecca M. Mitchell, Simon Kariuki, Christopher Odero, Peter Otieno, Kephas Otieno, Philip Onyona, Vincent Were, Ryan E. Wiegand, John E. Gimnig, Edward D. Walker, Meghna Desai, Ya Ping Shi

Open Access Research

The impact of behaviour change communication on the use of insecticide treated nets: a secondary analysis of ten post-campaign surveys from Nigeria

Albert Kilian, Harriet Lawford, Chinazo N. Ujuju, Tarekegn A. Abeku, Ernest Nwokolo, Festus Okoh, Ebenezer Baba

Open Access Research

A comparative molecular survey of malaria prevalence among Eastern chimpanzee populations in Issa Valley (Tanzania) and Kalinzu (Uganda)

Mwanahamisi I. Mapua, Klára J. Petrželková, Jade Burgunder, Eva Dadáková, Kristýna Brožová, Kristýna Hrazdilová, Fiona A. Stewart, Alex K. Piel, Peter Vallo, Hans-Peter Fuehrer, Chie Hashimoto, David Modrý, Moneeb A. Qablan

Open Access Research

Investigation of mechanisms of bendiocarb resistance in Anopheles gambiae populations from the city of Yaoundé, Cameroon

Christophe Antonio-Nkondjio, Rodolphe Poupardin, Billy Fossog Tene, Edmond Kopya, Carlo Costantini, Parfait Awono-Ambene, Charles S. Wondji

Open Access Research

Functional genomic analyses of Enterobacter, Anopheles and Plasmodium reciprocal interactions that impact vector competence

Nathan J. Dennison, Raúl G. Saraiva, Chris M. Cirimotich, Godfree Mlambo, Emmanuel F. Mongodin, George Dimopoulos

Open Access Research

Influence of the agrochemicals used for rice and vegetable cultivation on insecticide resistance in malaria vectors in southern Côte d’Ivoire

Mouhamadou S. Chouaïbou, Behi K. Fodjo, Gilbert Fokou, Ouattara F. Allassane, Benjamin G. Koudou, Jean-Philippe David, Christophe Antonio-Nkondjio, Hilary Ranson, Bassirou Bonfoh

Open Access Research

Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria

Brian DellaValle, Casper Hempel, Trine Staalsoe, Flemming Fryd Johansen, Jørgen Anders Lindholm Kurtzhals

Open Access Research

Behavioural and neurological symptoms accompanied by cellular neuroinflammation in IL-10-deficient mice infected with Plasmodium chabaudi

Kyle D. Wilson, Sonja J. Stutz, Lorenzo F. Ochoa, Gustavo A. Valbuena, Petra D. Cravens, Kelly T. Dineley, Gracie Vargas, Robin Stephens

Open Access Case report

Non-falciparum malaria in Dakar: a confirmed case of Plasmodium ovale wallikeri infection

Mamadou A. Diallo, Aida S. Badiane, Khadim Diongue, Awa Deme, Naomi W. Lucchi, Marie Gaye, Tolla Ndiaye, Mouhamadou Ndiaye, Louise K. Sene, Abdoulaye Diop, Amy Gaye, Yaye D. Ndiaye, Diama Samb, Mamadou S. Yade, Omar Ndir, Venkatachalam Udhayakumar, Daouda Ndiaye

Open Access Research

Burden of malaria is higher among children in an internal displacement camp compared to a neighbouring village in the Democratic Republic of the Congo

Rhianna Charchuk, Makelele Katsuva Jean Paul, Kasereka Masumbuko Claude, Stan Houston, Michael T. Hawkes

Open Access Research

Selection of N86F184D1246 haplotype of Pfmrd1 gene by artemether–lumefantrine drug pressure on Plasmodium falciparum populations in Senegal

Aminata Mbaye, Baba Dieye, Yaye D. Ndiaye, Amy K. Bei, Affara Muna, Awa B. Deme, Mamadou S. Yade, Khadim Diongue, Amy Gaye, Ibrahima M. Ndiaye, Tolla Ndiaye, Mouhamad Sy, Mamadou A. Diallo, Aida S. Badiane, Mouhamadou Ndiaye, Mame C. Seck, Ngayo Sy, Ousmane Koita, Donald J. Krogstad, Davis Nwakanma, Daouda Ndiaye

Open Access Research

High mobility, low access thwarts interventions among seasonal workers in the Greater Mekong Sub-region: lessons from the malaria containment project

Sara E. Canavati, Cesia E. Quintero, Harriet L. S. Lawford, Sovann Yok, Dysoley Lek, Jack S. Richards, Maxine Anne Whittaker

Open Access Research

Adding a single low-dose of primaquine (0.25 mg/kg) to artemether-lumefantrine did not compromise treatment outcome of uncomplicated Plasmodium falciparum malaria in Tanzania: a randomized, single-blinded clinical trial

Richard Mwaiswelo, Billy Ngasala, Irina Jovel, Berit Aydin-Schmidt, Roland Gosling, Zul Premji, Bruno Mmbando, Anders Björkman, Andreas Mårtensson

Open Access Research

Prevalence of malaria in pregnancy in southern Laos: a cross-sectional survey

Valérie Briand, Jean-Yves Le Hesran, Mayfong Mayxay, Paul N. Newton, Gwladys Bertin, Sandrine Houzé, Sommay Keomany, Yom Inthavong, Nanthasane Vannavong, Keobouphaphone Chindavongsa, Bouasy Hongvanthong, Nadine Fievet

Open Access Research

Reductions in malaria in pregnancy and adverse birth outcomes following indoor residual spraying of insecticide in Uganda

Mary K. Muhindo, Abel Kakuru, Paul Natureeba, Patricia Awori, Peter Olwoch, John Ategeka, Patience Nayebare, Tamara D. Clark, Atis Muehlenbachs, Michelle Roh, Betty Mpeka, Bryan Greenhouse, Diane V. Havlir, Moses R. Kamya, Grant Dorsey, Prasanna Jagannathan

Open Access Research

Reviewing South Africa’s malaria elimination strategy (2012–2018): progress, challenges and priorities

Jaishree Raman, Natashia Morris, John Frean, Basil Brooke, Lucille Blumberg, Philip Kruger, Aaron Mabusa, Eric Raswiswi, Bridget Shandukani, Eunice Misani, Mary-Anne Groepe, Devanand Moonasar

Open Access Research

Acceptability of malaria rapid diagnostic tests administered by village health workers in Pangani District, North eastern Tanzania

Adiel K. Mushi, Julius J. Massaga, Celine I. Mandara, Godfrey M. Mubyazi, Filbert Francis, Mathias Kamugisha, Jenesta Urassa, Martha Lemnge, Fidelis Mgohamwende, Sigbert Mkude, Joanna Armstrong Schellenberg

Open Access Research

Cow-baited tents are highly effective in sampling diverse Anopheles malaria vectors in Cambodia

Brandyce St. Laurent, Kolthida Oy, Becky Miller, Elizabeth B. Gasteiger, Eunjae Lee, Siv Sovannaroth, Robert W. Gwadz, Jennifer M. Anderson, Rick M. Fairhurst

Open Access Research

Malaria elimination challenges in Mesoamerica: evidence of submicroscopic malaria reservoirs in Guatemala

Shirley Evelyn Lennon, Adolfo Miranda, Juliana Henao, Andres F. Vallejo, Julianh Perez, Alvaro Alvarez, Myriam Arévalo-Herrera, Sócrates Herrera

Open Access Research

Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in Bandiagara

Mahamadou A. Thera, Drissa Coulibaly, Abdoulaye K. Kone, Ando B. Guindo, Karim Traore, Abdourhamane H. Sall, Issa Diarra, Modibo Daou, Idrissa M. Traore, Youssouf Tolo, Mady Sissoko, Amadou Niangaly, Charles Arama, Mounirou Baby, Bourema Kouriba, Mahamadou S. Sissoko, Issaka Sagara, Ousmane B. Toure, Amagana Dolo, Dapa A. Diallo, Edmond Remarque, Roma Chilengi, Ramadhani Noor, Sanie Sesay, Alan Thomas, Clemens H. Kocken, Bart W. Faber, Egeruan Babatunde Imoukhuede, Odile Leroy, Ogobara K. Doumbo

Open Access Research

Prevalence and diagnostics of congenital malaria in rural Burundi, a cross-sectional study

Jorgen Stassijns, Wilma van den Boogaard, Pieter Pannus, Alphonse Nkunzimana, Anna Rosanas-Urgell

Open Access Research

A prospective cohort study to assess the micro-epidemiology of Plasmodium falciparum clinical malaria in Ilha Josina Machel (Manhiça, Mozambique)

Beatriz Galatas, Caterina Guinovart, Quique Bassat, John J. Aponte, Lídia Nhamússua, Eusebio Macete, Francisco Saúte, Pedro Alonso, Pedro Aide

Open Access Research

Immune response pattern in recurrent Plasmodium vivax malaria

Yury Oliveira Chaves, Allyson Guimarães da Costa, Marcelo Luís Monteiro Pereira, Marcus Vinícius Guimarães de Lacerda, Jordana Grazziela Coelho-dos-Reis, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Adriana Malheiro, Wuelton Marcelo Monteiro, Patrícia Puccinelli Orlandi, Claudio Romero Farias Marinho, Paulo Afonso Nogueira

Open Access Research

Assessing the asymptomatic reservoir and dihydroartemisinin–piperaquine effectiveness in a low transmission setting threatened by artemisinin resistant Plasmodium falciparum

Grégoire Falq, Rafael Van Den Bergh, Martin De Smet, William Etienne, Chea Nguon, Huy Rekol, Mallika Imwong, Arjen Dondorp, Jean-Marie Kindermans

Open Access Research

Eave tubes for malaria control in Africa: initial development and semi-field evaluations in Tanzania

Eleanore D. Sternberg, Kija R. Ng’habi, Issa N. Lyimo, Stella T. Kessy, Marit Farenhorst, Matthew B. Thomas, Bart G. J. Knols, Ladslaus L. Mnyone

Open Access Research

Malaria and large dams in sub-Saharan Africa: future impacts in a changing climate

Solomon Kibret, Jonathan Lautze, Matthew McCartney, Luxon Nhamo, G. Glenn Wilson

Open Access Research

Eave tubes for malaria control in Africa: a modelling assessment of potential impact on transmission

Jessica L. Waite, Penelope A. Lynch, Matthew B. Thomas

Open Access Research

Distribution and prevalence of malaria parasites among long-tailed macaques (Macaca fascicularis) in regional populations across Southeast Asia

Xinjun Zhang, Khamisah Abdul Kadir, Leslie Fabiola Quintanilla-Zariñan, Jason Villano, Paul Houghton, Hongli Du, Balbir Singh, David Glenn Smith

Open Access Research

Plasmodium cynomolgi infections in rhesus macaques display clinical and parasitological features pertinent to modelling vivax malaria pathology and relapse infections

Chester Joyner, Alberto Moreno, Esmeralda V. S. Meyer, Monica Cabrera-Mora, Amy Kong, Chris Ibegbu, Dalia Arafat, Dean Jones, Douglas P. Nace, Eberhard O. Voit, Jan Pohl, Jay Humphrey, Jeremy DeBarry, JoAnn Sullivan, Juan B. Gutierrez, Kevin J. Kevin , Luis L. Fonseca, Mark Styczynski, Mustafa Nural, Sarah T. Pruett, Stacey A. Lapp, Suman Pakala, Tracey J. Lamb, Tyrone Williams, Karan Uppal, ViLinh Tran, Weiwei Yin, Yi Yan, Jessica C. Kissinger, John W. Barnwell, Mary R. Galinski

Open Access Research

Selection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate–amodiaquine fixed dose combination or artemether–lumefantrine in Liberia

Sabina Dahlström Otienoburu, Oumou Maïga-Ascofaré, Birgit Schramm, Vincent Jullien, Joel J. Jones, Yah M. Zolia, Pascal Houzé, Elizabeth A. Ashley, Jean-René Kiechel, Philippe J. Guérin, Jacques Le Bras, Sandrine Houzé

Open Access Research

Comparative pharmacokinetics and pharmacodynamics of intravenous artelinate versus artesunate in uncomplicated Plasmodium coatneyi-infected rhesus monkey model

Paktiya Teja-Isavadharm, Duangsuda Siriyanonda, Maneerat Rasameesoraj, Amporn Limsalakpeth, Nitima Chanarat, Natthasorn Komcharoen, Peter J. Weina, David L. Saunders, Montip Gettayacamin, R. Scott Miller

Open Access Research

Economic burden of malaria on businesses in Ghana: a case for private sector investment in malaria control

Justice Nonvignon, Genevieve Cecilia Aryeetey, Keziah L. Malm, Samuel Agyei Agyemang, Vivian N. A. Aubyn, Nana Yaw Peprah, Constance N. Bart-Plange, Moses Aikins

Open Access Research

In vivo efficacy of artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria: an open-randomized, non-inferiority clinical trial in South Kivu, Democratic Republic of Congo

Marit de Wit, Anna L. Funk, Krystel Moussally, David Aksanti Nkuba, Ruby Siddiqui, Karla Bil, Erwan Piriou, Aldert Bart, Patrick Bahizi Bizoza, Teun Bousema

Open Access Research

Field evaluation of diagnostic performance of malaria rapid diagnostic tests in western Kenya

Elizabeth W. Wanja, Nickline Kuya, Collins Moranga, Mark Hickman, Jacob D. Johnson, Carolyne Moseti, Lalaine Anova, Bernhards Ogutu, Colin Ohrt

Open Access Research

Characterization of fine specificity of the immune response to a Plasmodium falciparum rhoptry neck protein, PfAARP

Aakanksha Kalra, Paushali Mukherjee, Virander S. Chauhan

Open Access Research

A malariometric survey of under-fives residing in indoor residual spraying-implementing and non-implementing communities of Lagos, Nigeria

Babatunde A. Odugbemi, Kikelomo O. Wright, Adebayo T. Onajole, Yetunde A. Kuyinu, Olayinka O. Goodman, Tinuola O. Odugbemi, Olumuyiwa O. Odusanya

Open Access Research

The increasing importance of Plasmodium ovale and Plasmodium malariae in a malaria elimination setting: an observational study of imported cases in Jiangsu Province, China, 2011–2014

Yuanyuan Cao, Weiming Wang, Yaobao Liu, Chris Cotter, Huayun Zhou, Guoding Zhu, Jianxia Tang, Feng Tang, Feng Lu, Sui Xu, Yaping Gu, Chao Zhang, Julin Li, Jun Cao

Open Access Research

Multi-method assessment of patients with febrile illness reveals over-diagnosis of malaria in rural Uganda

Ria R. Ghai, Mary I. Thurber, Azza El Bakry, Colin A. Chapman, Tony L. Goldberg

Open Access Case report

Plasmodium falciparum and Mycoplasma pneumoniae co-infection presenting with cerebral malaria manifesting orofacial dyskinesia and haemophagocytic lymphohistiocytosis

Praveen Weeratunga, Gowri Rathnayake, Ahalya Sivashangar, Panduka Karunanayake, Ariaranee Gnanathasan, Thashi Chang

Open Access Case report

Intravascular haemolysis with haemoglobinuria in a splenectomized patient with severe Plasmodium knowlesi malaria

Bridget E. Barber, Matthew J. Grigg, Timothy William, Tsin W. Yeo, Nicholas M. Anstey

Open Access Research

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

Kazutoyo Miura, Will J. R. Stone, Karin M. Koolen, Bingbing Deng, Luwen Zhou, Geert-Jan van Gemert, Emily Locke, Merribeth Morin, Teun Bousema, Robert W. Sauerwein, Carole A. Long, Koen J. Dechering

Open Access Research

Neutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury

Marlies E. van Wolfswinkel, Liese C. Koopmans, Dennis A. Hesselink, Ewout J. Hoorn, Rob Koelewijn, Jaap J. van Hellemond, Perry J. J. van Genderen

Open Access Research

An improved mosquito electrocuting trap that safely reproduces epidemiologically relevant metrics of mosquito human-feeding behaviours as determined by human landing catch

Nicodem J. Govella, Deodatus F. Maliti, Amos T. Mlwale, John P. Masallu, Nosrat Mirzai, Paul C. D. Johnson, Heather M. Ferguson, Gerry F. Killeen

Open Access Research

Pathway-specific inhibition of primaquine metabolism by chloroquine/quinine

Pius S. Fasinu, Babu L. Tekwani, Bharathi Avula, Narayan D. Chaurasiya, N. P. Dhammika Nanayakkara, Yan-Hong Wang, Ikhlas A. Khan, Larry A. Walker

Open Access Research

Assets and challenges facing caregivers when managing malaria in young children in rural Uganda

Rosemin Kassam, John Collins, Richard Sekiwunga

Open Access Research

Malaria risk factor assessment using active and passive surveillance data from Aceh Besar, Indonesia, a low endemic, malaria elimination setting with Plasmodium knowlesi, Plasmodium vivax, and Plasmodium falciparum

Herdiana Herdiana, Chris Cotter, Farah N. Coutrier, Iska Zarlinda, Brittany W. Zelman, Yusrifar Kharisma Tirta, Bryan Greenhouse, Roly D. Gosling, Peter Baker, Maxine Whittaker, Michelle S. Hsiang

Open Access Research

A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study

James S. McCarthy, Thomas Rückle, Elhadj Djeriou, Cathy Cantalloube, Daniel Ter-Minassian, Mark Baker, Peter O’Rourke, Paul Griffin, Louise Marquart, Rob Hooft van Huijsduijnen, Jörg J. Möhrle

Open Access Research

Characterizing microscopic and submicroscopic malaria parasitaemia at three sites with varied transmission intensity in Uganda

John Rek, Shereen Katrak, Hannah Obasi, Patience Nayebare, Agaba Katureebe, Elijah Kakande, Emmanuel Arinaitwe, Joaniter I. Nankabirwa, Prasanna Jagannathan, Chris Drakeley, Sarah G. Staedke, David L. Smith, Teun Bousema, Moses Kamya, Philip J. Rosenthal, Grant Dorsey, Bryan Greenhouse

Open Access Research

Impact of interventions on malaria in internally displaced persons along the China–Myanmar border: 2011–2014

Guofa Zhou, Eugenia Lo, Daibin Zhong, Xiaoming Wang, Ying Wang, Sameer Malla, Ming-chieh Lee, Zhaoqing Yang, Liwang Cui, Guiyun Yan

Open Access Research

Probucol dramatically enhances dihydroartemisinin effect in murine malaria

Aiko Kume, Dang Trinh Minh Anh, Mototada Shichiri, Noriko Ishida, Hiroshi Suzuki

Open Access Research

The use of formative research to inform the design of a seasonal malaria chemoprevention intervention in northern Nigeria

Clare E. Strachan, Musa Kana, Sandrine Martin, John Dada, Naome Wandera, Madeleine Marasciulo, Helen Counihan, Maxwell Kolawole, Tanimu Babale, Prudence Hamade, Sylvia R. Meek, Ebenezer Baba

Open Access Meeting report

Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report

Arnaud Chêne, Sophie Houard, Morten A. Nielsen, Sophia Hundt, Flavia D’Alessio, Sodiomon B. Sirima, Adrian J. F. Luty, Patrick Duffy, Odile Leroy, Benoit Gamain, Nicola K. Viebig

Open Access Research

Safety, efficacy and pharmacokinetic evaluations of a new coated chloroquine tablet in a single-arm open-label non-comparative trial in Brazil: a step towards a user-friendly malaria vivax treatment

Dhelio Pereira, André Daher, Graziela Zanini, Ivan Maia, Lais Fonseca, Luciana Pitta, Rosilene Ruffato, Paola Marchesini, Cor Jesus Fontes

Open Access Research

Cedrol, a malaria mosquito oviposition attractant is produced by fungi isolated from rhizomes of the grass Cyperus rotundus

Lynda K. Eneh, Hiromi Saijo, Anna-Karin Borg-Karlson, Jenny M. Lindh, Gunaratna Kuttuva Rajarao

Open Access Case report

Failure of dihydroartemisinin plus piperaquine treatment of falciparum malaria by under-dosing in an overweight patient

Jean Baptiste Roseau, Bruno Pradines, Nicolas Paleiron, Serge Vedy, Marylin Madamet, Fabrice Simon, Emilie Javelle

Open Access Research

Impact of the Mass Drug Administration for malaria in response to the Ebola outbreak in Sierra Leone

Maru Aregawi, Samuel J. Smith, Musa Sillah-Kanu, John Seppeh, Anitta R. Y. Kamara, Ryan O. Williams, John J. Aponte, Andrea Bosman, Pedro Alonso

Open Access Research

Natural products from Zanthoxylum heitzii with potent activity against the malaria parasite

Christopher Dean Goodman, Ingvild Austarheim, Vanessa Mollard, Bertin Mikolo, Karl Egil Malterud, Geoffrey I. McFadden, Helle Wangensteen

Open Access Research

Stage-dependent fate of Plasmodium falciparum-infected red blood cells in the spleen and sickle-cell trait-related protection against malaria

Seidina A. S. Diakité, Papa Alioune Ndour, Valentine Brousse, Frederick Gay, Camille Roussel, Sylvestre Biligui, Michaël Dussiot, Virginie Prendki, Tatiana M. Lopera-Mesa, Karim Traoré, Drissa Konaté, Saibou Doumbia, Jérôme Cros, Safi Dokmak, Rick M. Fairhurst, Mahamadou Diakité, Pierre A. Buffet

Open Access Research

Parasite dynamics in the peripheral blood and the placenta during pregnancy-associated malaria infection

Lauren M. Cohee, Linda Kalilani-Phiri, Patricia Mawindo, Sudhaunshu Joshi, Matthew Adams, Leo Kenefic, Christopher G. Jacob, Terrie E. Taylor, Miriam K. Laufer

Open Access Research

Geographic distribution of amino acid mutations in DHFR and DHPS in Plasmodium vivax isolates from Lao PDR, India and Colombia

Naowarat Saralamba, Supatchara Nakeesathit, Mayfong Mayxay, Paul N. Newton, Lyda Osorio, Jung-Ryong Kim, Nicholas J. White, Nicholas P. J. Day, Arjen M. Dondorp, Mallika Imwong

Open Access Research

Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses

Komi Gbédandé, Gilles Cottrell, Bertin Vianou, Samad Ibitokou, Aurax Fernando, Marita Troye-Blomberg, Ali Salanti, Kabirou Moutairou, Achille Massougbodji, Nicaise Tuikue Ndam, Philippe Deloron, Adrian J. F. Luty, Nadine Fievet

Open Access Research

Lay knowledge and management of malaria in Baringo county, Kenya

Edna N. Mutua, Salome A. Bukachi, Bernard K. Bett, Benson A. Estambale, Isaac K. Nyamongo

Open Access Research

The central role of national programme management for the achievement of malaria elimination: a cross case-study analysis of nine malaria programmes

Cara Smith Gueye, Gretchen Newby, Jim Tulloch, Laurence Slutsker, Marcel Tanner, Roland D. Gosling

Open Access Research

A novel method for mapping village-scale outdoor resting microhabitats of the primary African malaria vector, Anopheles gambiae

Julius R. Dewald, Douglas O. Fuller, Günter C. Müller, John C. Beier

Open Access Research

Quantitative, model-based estimates of variability in the generation and serial intervals of Plasmodium falciparum malaria

John H. Huber, Geoffrey L. Johnston, Bryan Greenhouse, David L. Smith, T. Alex Perkins

Open Access Research

Filling gaps on ivermectin knowledge: effects on the survival and reproduction of Anopheles aquasalis, a Latin American malaria vector

Vanderson S. Sampaio, Tatiana P. Beltrán, Kevin C. Kobylinski, Gisely C. Melo, José B. P. Lima, Sara G. M. Silva, Íria C. Rodriguez, Henrique Silveira, Maria G. V. B. Guerra, Quique Bassat, Paulo F. P. Pimenta, Marcus V. G. Lacerda, Wuelton M. Monteiro

Open Access Research

Plasmodium vivax msp-3α polymorphisms: analysis in the Indian subcontinent

Anju Verma, Hema Joshi, Vineeta Singh, Anup Anvikar, Neena Valecha

Open Access Research

Cost effectiveness of intermittent screening followed by treatment versus intermittent preventive treatment during pregnancy in West Africa: analysis and modelling of results from a non-inferiority trial

Silke Fernandes, Elisa Sicuri, Diawara Halimatou, James Akazili, Kalifa Boiang, Daniel Chandramohan, Sheikh Coulibaly, Sory Ibrahim Diawara, Kassoum Kayentao, Feiko ter Kuile, Pascal Magnussen, Harry Tagbor, John Williams, Arouna Woukeu, Matthew Cairns, Brian Greenwood, Kara Hanson

Open Access Research

The acceptability of mass administrations of anti-malarial drugs as part of targeted malaria elimination in villages along the Thai–Myanmar border

Ladda Kajeechiwa, May Myo Thwin, Paw Wah Shee, Nan Lin Yee, Elvina Elvina, Peapah Peapah, Kyawt Kyawt, Poe Thit Oo, William PoWah, Jacqueline Roger Min, Jacher Wiladphaingern, Lorenz von Seidlein, Suphak Nosten, Francois Nosten

Open Access Erratum

Erratum to: Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria

Brian DellaValle, Casper Hempel, Trine Staalsoe, Flemming Fryd Johansen, Jørgen Anders Lindholm Kurtzhals

Open Access Research

Performance and time to become negative after treatment of three malaria rapid diagnostic tests in low and high malaria transmission settings

Francesco Grandesso, Carolyn Nabasumba, Dan Nyehangane, Anne-Laure Page, Mathieu Bastard, Martin De Smet, Yap Boum, Jean-François Etard

Open Access Research

Timing of in utero malaria exposure influences fetal CD4 T cell regulatory versus effector differentiation

Mary Prahl, Prasanna Jagannathan, Tara I. McIntyre, Ann Auma, Lila Farrington, Samuel Wamala, Mayimuna Nalubega, Kenneth Musinguzi, Kate Naluwu, Esther Sikyoma, Rachel Budker, Hilary Vance, Pamela Odorizzi, Patience Nayebare, John Ategeka, Abel Kakuru, Diane V. Havlir, Moses R. Kamya, Grant Dorsey, Margaret E. Feeney

Open Access Research

Therapeutic efficacy of artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria from three highly malarious states in India

Praveen K. Bharti, Man M. Shukla, Pascal Ringwald, Sri Krishna, Pushpendra P. Singh, Ajay Yadav, Sweta Mishra, Usha Gahlot, Jai P. Malaiya, Amit Kumar, Shambhu Prasad, Pradeep Baghel, Mohan Singh, Jaiprakash Vadadi, Mrigendra P. Singh, Maria Dorina G. Bustos, Leonard I. Ortega, Eva-Maria Christophel, Sher S. Kashyotia, Gagan S. Sonal, Neeru Singh

Open Access Research

Asymptomatic malaria, growth status, and anaemia among children in Lao People’s Democratic Republic: a cross-sectional study

Takeshi Akiyama, Tiengkham Pongvongsa, Souraxay Phrommala, Tomoyo Taniguchi, Yuba Inamine, Rie Takeuchi, Tadashi Watanabe, Futoshi Nishimoto, Kazuhiko Moji, Shigeyuki Kano, Hisami Watanabe, Jun Kobayashi

Open Access Research

Malaria burden in a birth cohort of HIV-exposed uninfected Ugandan infants living in a high malaria transmission setting

Abel Kakuru, Paul Natureeba, Mary K. Muhindo, Tamara D. Clark, Diane V. Havlir, Deborah Cohan, Grant Dorsey, Moses R. Kamya, Theodore Ruel

Open Access Research

Contemporary epidemiological overview of malaria in Madagascar: operational utility of reported routine case data for malaria control planning

Rosalind E. Howes, Sedera Aurélien Mioramalala, Brune Ramiranirina, Thierry Franchard, Andry Joeliarijaona Rakotorahalahy, Donal Bisanzio, Peter W. Gething, Peter A. Zimmerman, Arsène Ratsimbasoa

Open Access Research

Malaria incidence in Myanmar 2005–2014: steady but fragile progress towards elimination

Thet Thet Mu, Aye Aye Sein, Tint Tint Kyi, Myo Min, Ne Myo Aung, Nicholas M. Anstey, Myat Phone Kyaw, Chit Soe, Mar Mar Kyi, Josh Hanson

Open Access Research

Contribution of the private sector healthcare service providers to malaria diagnosis in a prevention of re-introduction setting

Sumadhya Deepika Fernando, Priyani Dharmawardana, Geethanee Epasinghe, Niroshana Senanayake, Chaturaka Rodrigo, Risintha Premaratne, Rajitha Wickremasinghe

Open Access Research

The effectiveness of a nationwide universal coverage campaign of insecticide-treated bed nets on childhood malaria in Malawi

Collins O. F. Zamawe, Kanan Nakamura, Akira Shibanuma, Masamine Jimba

Open Access Research

Malaria investigation and treatment of children admitted to county hospitals in western Kenya

Beatrice I. Amboko, Philip Ayieko, Morris Ogero, Thomas Julius, Grace Irimu, Mike English

Open Access Research

Health worker and policy-maker perspectives on use of intramuscular artesunate for pre-referral and definitive treatment of severe malaria at health posts in Ethiopia

Takele Kefyalew, Zelalem Kebede, Dawit Getachew, David Mukanga, Tessema Awano, Agonafer Tekalegne, Esey Batisso, Wasihun Edossa, Emebet Mekonnen, James Tibenderana, Ebenezer Sheshi Baba, Constance Shumba, Joaniter I. Nankabirwa, Prudence Hamade

Open Access Research

Household clustering of asymptomatic malaria infections in Xepon district, Savannakhet province, Lao PDR

Tiengkham Pongvongsa, Daisuke Nonaka, Moritoshi Iwagami, Masami Nakatsu, Panom Phongmany, Futoshi Nishimoto, Jun Kobayashi, Bouasy Hongvanthon, Paul T. Brey, Kazuhiko Moji, Toshihiro Mita, Shigeyuki Kano

Open Access Research

Geographical patterns of malaria transmission based on serological markers for falciparum and vivax malaria in Ratanakiri, Cambodia

Karen Kerkhof, Vincent Sluydts, Somony Heng, Saorin Kim, Myrthe Pareyn, Laura Willen, Lydie Canier, Siv Sovannaroth, Didier Ménard, Tho Sochantha, Marc Coosemans, Lies Durnez

Open Access Research

Assessing temporal associations between environmental factors and malaria morbidity at varying transmission settings in Uganda

Ruth Kigozi, Kate Zinszer, Arthur Mpimbaza, Asadu Sserwanga, Simon P. Kigozi, Moses Kamya

Open Access Research

Facilitating factors and barriers to malaria research utilization for policy development in Malawi

Chikondi A. Mwendera, Christiaan de Jager, Herbert Longwe, Kamija Phiri, Charles Hongoro, Clifford M. Mutero

Open Access Research

Exceptionally long-range haplotypes in Plasmodium falciparum chromosome 6 maintained in an endemic African population

Alfred Amambua-Ngwa, Bakary Danso, Archibald Worwui, Sukai Ceesay, Nwakanma Davies, David Jeffries, Umberto D’Alessandro, David Conway

Open Access Research

Genetic diversity of the merozoite surface protein-3 gene in Plasmodium falciparum populations in Thailand

Sittiporn Pattaradilokrat, Vorthon Sawaswong, Phumin Simpalipan, Morakot Kaewthamasorn, Napaporn Siripoon, Pongchai Harnyuttanakorn

Open Access Research

Ex vivo piperaquine resistance developed rapidly in Plasmodium falciparum isolates in northern Cambodia compared to Thailand

Suwanna Chaorattanakawee, Chanthap Lon, Krisada Jongsakul, Jariyanart Gawee, Somethy Sok, Siratchana Sundrakes, Nareth Kong, Chatchadaporn Thamnurak, Soklyda Chann, Sorayut Chattrakarn, Chantida Praditpol, Nillawan Buathong, Nichapat Uthaimongkol, Philip Smith, Narongrid Sirisopana, Rekol Huy, Satharath Prom, Mark M. Fukuda, Delia Bethell, Douglas S. Walsh, Charlotte Lanteri, David Saunders

Open Access Research

Malaria diagnosis and mapping with m-Health and geographic information systems (GIS): evidence from Uganda

Alberto Larocca, Roberto Moro Visconti, Michele Marconi

Open Access Research

Increasing understanding of the relationship between geographic access and gendered decision-making power for treatment-seeking for febrile children in the Chikwawa district of Malawi

Victoria L. Ewing, Rachel Tolhurst, Andrew Kapinda, Esther Richards, Dianne J. Terlouw, David G. Lalloo

Open Access Erratum

Erratum to: Diagnosis and treatment based on quantitative PCR after controlled human malaria infection

Jona Walk, Remko Schats, Marijke C. C. Langenberg, Isaie J. Reuling, Karina Teelen, Meta Roestenberg, Cornelus C. Hermsen, Leo G. Visser, Robert W. Sauerwein

Open Access Review

Community engagement and population coverage in mass anti-malarial administrations: a systematic literature review

Bipin Adhikari, Nicola James, Gretchen Newby, Lorenz von Seidlein, Nicholas J. White, Nicholas P. J. Day, Arjen M. Dondorp, Christopher Pell, Phaik Yeong Cheah

Open Access Review

The effect of malaria and anti-malarial drugs on skeletal and cardiac muscles

Mauro Toledo Marrelli, Marco Brotto

Open Access Case report

Failure of dihydroartemisinin-piperaquine treatment of uncomplicated Plasmodium falciparum malaria in a traveller coming from Ethiopia

Federico Gobbi, Dora Buonfrate, Michela Menegon, Gianluigi Lunardi, Andrea Angheben, Carlo Severini, Stefania Gori, Zeno Bisoffi

Open Access Research

Characterization of Plasmodium falciparum ATP-dependent DNA helicase RuvB3

Paviga Limudomporn, Saengduen Moonsom, Ubolsree Leartsakulpanich, Pattra Suntornthiticharoen, Songsak Petmitr, Michael Weinfeld, Porntip Chavalitshewinkoon-Petmitr

Open Access Research

High prevalence of Plasmodium falciparum gametocyte infections in school-age children using molecular detection: patterns and predictors of risk from a cross-sectional study in southern Malawi

Jenna E. Coalson, Jenny A. Walldorf, Lauren M. Cohee, Miriam D. Ismail, Don Mathanga, Regina Joice Cordy, Matthias Marti, Terrie E. Taylor, Karl B. Seydel, Miriam K. Laufer, Mark L. Wilson

Open Access Research

Genetic diversity of the Pvk12 gene in Plasmodium vivax from the China-Myanmar border area

Shuang Deng, Yonghua Ruan, Yao Bai, Yue Hu, Zeshuai Deng, Yongshu He, Rui Ruan, Yanrui Wu, Zhaoqing Yang, Liwang Cui

Open Access Research

Serological markers to measure recent changes in malaria at population level in Cambodia

Karen Kerkhof, Vincent Sluydts, Laura Willen, Saorin Kim, Lydie Canier, Somony Heng, Takafumi Tsuboi, Tho Sochantha, Siv Sovannaroth, Didier Ménard, Marc Coosemans, Lies Durnez

Open Access Research

Assessing demand-side barriers to uptake of intermittent preventive treatment for malaria in pregnancy: a qualitative study in two regions of Uganda

Christian Rassi, Kirstie Graham, Rebecca King, James Ssekitooleko, Patrobas Mufubenga, Sam Siduda Gudoi

Open Access Research

Plasmodium infection and oxidative status in breeding great tits, Parus major

Jessica Delhaye, Tania Jenkins, Philippe Christe

Open Access Research

Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers

Barriere A. Y. Fodjo, Njika Atemnkeng, Livo Esemu, Emile K. Yuosembom, Isabella A. Quakyi, Viviane H. M. Tchinda, Joseph Smith, Ali Salanti, Jude Bigoga, Diane W. Taylor, Rose G. F. Leke, Anna Babakhanyan

Open Access Research

Scaling-up the use of sulfadoxine-pyrimethamine for the preventive treatment of malaria in pregnancy: results and lessons on scalability, costs and programme impact from three local government areas in Sokoto State, Nigeria

Nosa Orobaton, Anne M. Austin, Dele Abegunde, Mohammed Ibrahim, Zainab Mohammed, Jumare Abdul-Azeez, Hakeem Ganiyu, Zwalle Nanbol, Bolaji Fapohunda, Katherine Beal

Open Access Research

Optimal price subsidies for appropriate malaria testing and treatment behaviour

Kristian Schultz Hansen, Tine Hjernø Lesner, Lars Peter Østerdal

Open Access Methodology

A new tool for the chemical genetic investigation of the Plasmodium falciparum Pfnek-2 NIMA-related kinase

Deborah F. Mitcheson, Andrew R. Bottrill, Katherine Carr, Christopher R. Coxon, Celine Cano, Bernard T. Golding, Roger J. Griffin, Andrew M. Fry, Christian Doerig, Richard Bayliss, Andrew B. Tobin

Open Access Research

Treatment-seeking behaviour and associated costs for malaria in Papua, Indonesia

Muhammad Karyana, Angela Devine, Enny Kenangalem, Lenny Burdarm, Jeanne Rini Poespoprodjo, Ram Vemuri, Nicholas M. Anstey, Emiliana Tjitra, Ric N. Price, Shunmay Yeung

Open Access Research

Limited genetic diversity in the PvK12 Kelch protein in Plasmodium vivax isolates from Southeast Asia

Meilian Wang, Faiza Amber Siddiqui, Qi Fan, Enjie Luo, Yaming Cao, Liwang Cui

Open Access Research

The changing malaria landscape in Aseer region, Kingdom of Saudi Arabia: 2000–2015

Ali Mohamed Alshahrani, Tarig M. Abdelgader, Ibrahim Saeed, AbdulRhman Al-Akhshami, Mohamed Al-Ghamdi, Mohammed H. Al-Zahrani, Ibrahim El Hassan, David Kyalo, Robert W. Snow

Open Access Methodology

Comparison of molecular quantification of Plasmodium falciparum gametocytes by Pfs25 qRT-PCR and QT-NASBA in relation to mosquito infectivity

Helmi Pett, Bronner P. Gonçalves, Alassane Dicko, Issa Nébié, Alfred B. Tiono, Kjerstin Lanke, John Bradley, Ingrid Chen, Halimatou Diawara, Almahamoudou Mahamar, Harouna M. Soumare, Sekou F. Traore, Ibrahima Baber, Sodiomon B. Sirima, Robert Sauerwein, Joelle Brown, Roly Gosling, Ingrid Felger, Chris Drakeley, Teun Bousema

Open Access Research

Plasmodium vivax multidrug resistance-1 gene polymorphism in French Guiana

Emilie Faway, Lise Musset, Stéphane Pelleau, Béatrice Volney, Jessica Casteras, Valérie Caro, Didier Menard, Sébastien Briolant, Eric Legrand

Open Access Research

Analysis of anti-malarial resistance markers in pfmdr1 and pfcrt across Southeast Asia in the Tracking Resistance to Artemisinin Collaboration

Krongkan Srimuang, Olivo Miotto, Pharath Lim, Rick M. Fairhurst, Dominic P. Kwiatkowski, Charles J. Woodrow, Mallika Imwong

Open Access Research

Identification and characterization of microRNAs expressed in the African malaria vector Anopheles funestus life stages using high throughput sequencing

Mushal Allam, Belinda L. Spillings, Hiba Abdalla, Darlington Mapiye, Lizette L. Koekemoer, Alan Christoffels

Open Access Methodology

A monoclonal antibody-based immunoassay to measure the antibody response against the repeat region of the circumsporozoite protein of Plasmodium falciparum

Kristina Radin, Frederic Clement, Erik Jongert, Yann G. J. Sterckx, Christian Ockenhouse, Jason Regules, Franck Lemiale, Geert Leroux-Roels

Open Access Research

Development and validation of a rapid assessment tool for malaria prevention

Judith Nekesa Mangeni, Diana Menya, Andrew Obala, Alyssa Platt, Wendy Prudhomme O’Meara

Open Access Research

Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses

Christoph M. Janitzek, Sungwa Matondo, Susan Thrane, Morten A. Nielsen, Reginald Kavishe, Steve B. Mwakalinga, Thor G. Theander, Ali Salanti, Adam F. Sander

Open Access Research

Risk assessment of malaria in land border regions of China in the context of malaria elimination

Qian Zhang, Junling Sun, Zike Zhang, Qibin Geng, Shengjie Lai, Wenbiao Hu, Archie C. A. Clements, Zhongjie Li

Open Access Research

Association between malaria immunity and pregnancy outcomes among Malawian pregnant women receiving nutrient supplementation

Upeksha P. Chandrasiri, Freya J. I. Fowkes, James G. Beeson, Jack S. Richards, Steve Kamiza, Kenneth Maleta, Per Ashorn, Stephen J. Rogerson

Open Access Research

Post-exposure serological responses to malaria parasites in potential blood donors

Daniela Portugal-Calisto, Ana Raquel Ferreira, Marcelo Sousa Silva, Rosa Teodósio

Open Access Research

Does fluoride influence oviposition of Anopheles stephensi in stored water habitats in an urban setting?

Shalu Thomas, Sangamithra Ravishankaran, N. A. Johnson Amala Justin, Aswin Asokan, T. Maria Jusler Kalsingh, Manu Thomas Mathai, Neena Valecha, Alex Eapen

Open Access Research

Parasitological correlates of Plasmodium ovale curtisi and Plasmodium ovale wallikeri infection

Melissa S. Phuong, Rachel Lau, Filip Ralevski, Andrea K. Boggild

Open Access Research

An integrated risk and vulnerability assessment framework for climate change and malaria transmission in East Africa

Esther Achieng Onyango, Oz Sahin, Alex Awiti, Cordia Chu, Brendan Mackey

Open Access Research

Reduction in malaria prevalence and increase in malaria awareness in endemic districts of Bangladesh

Mohammad Shafiul Alam, Mohammad Moktadir Kabir, Mohammad Sharif Hossain, Shamsun Naher, Nur E. Naznin Ferdous, Wasif Ali Khan, Dinesh Mondal, Jahirul Karim, A. K. M. Shamsuzzaman, Be-Nazir Ahmed, Akramul Islam, Rashidul Haque

Open Access Research

Asymptomatic only at first sight: malaria infection among schoolchildren in highland Rwanda

Kevin C. Sifft, Dominik Geus, Caritas Mukampunga, Jean Claude Mugisha, Felix Habarugira, Kira Fraundorfer, Claude Bayingana, Jules Ndoli, Irenee Umulisa, Corine Karema, George von Samson-Himmelstjerna, Toni Aebischer, Peter Martus, Augustin Sendegeya, Jean Bosco Gahutu, Frank P. Mockenhaupt

Open Access Research

Low prevalence of laboratory-confirmed malaria in clinically diagnosed adult women from the Wakiso district of Uganda

Sergey Yegorov, Ronald M. Galiwango, Aloysious Ssemaganda, Moses Muwanga, Irene Wesonga, George Miiro, David A. Drajole, Kevin C. Kain, Noah Kiwanuka, Bernard S. Bagaya, Rupert Kaul

Open Access Review

Antibiotics in malaria therapy: which antibiotics except tetracyclines and macrolides may be used against malaria?

Tiphaine Gaillard, Marylin Madamet, Francis Foguim Tsombeng, Jérôme Dormoi, Bruno Pradines

Open Access Research

Plasmodium malariae and Plasmodium ovale infections in the China–Myanmar border area

Peipei Li, Zhenjun Zhao, Hua Xing, Wenli Li, Xiaotong Zhu, Yaming Cao, Zhaoqing Yang, Jetsumon Sattabongkot, Guiyun Yan, Qi Fan, Liwang Cui

Open Access Erratum

Erratum to: Development and evaluation of mosquito-electrocuting traps as alternatives to the human landing catch technique for sampling host-seeking malaria vectors

Deodatus V. Maliti, Nicodem J. Govella, Gerry F. Killeen, Nosrat Mirzai, Paul C. D. Johnson, Katharina Kreppel, Heather M. Ferguson

Open Access Research

Allele-specific antibodies to Plasmodium vivax merozoite surface protein-1: prevalence and inverse relationship to haemoglobin levels during infection

Nuno Sepúlveda, Cristiane Guimarães Morais, Luiza Carvalho Mourão, Matheus França Freire, Cor Jesus F. Fontes, Marcus Vinícius G. Lacerda, Chris J. Drakeley, Érika Martins Braga

Open Access Erratum

Erratum to: Natural products from Zanthoxylum heitzii with potent activity against the malaria parasite

Christopher Dean Goodman, Ingvild Austarheim, Vanessa Mollard, Bertin Mikolo, Karl Egil Malterud, Geoffrey I. McFadden, Helle Wangensteen

Open Access Research

Impact of placental Plasmodium falciparum malaria infection on the Cameroonian maternal and neonate’s plasma levels of some cytokines known to regulate T cells differentiation and function

Jean Claude Djontu, Stalone Siewe Siewe, Yolande Delphine Mpeke Edene, Benderli Christine Nana, Edwige Vanessa Chomga Foko, Jude Daiga Bigoga, Rose F. G. Leke, Rosette Megnekou

Open Access Research

Increasing insecticide resistance in Anopheles funestus and Anopheles arabiensis in Malawi, 2011–2015

Themba Mzilahowa, Martin Chiumia, Rex B. Mbewe, Veronica T. Uzalili, Madalitso Luka-Banda, Anna Kutengule, Don P. Mathanga, Doreen Ali, John Chiphwanya, John Zoya, Shadreck Mulenga, Wilfred Dodoli, Jennifer Bergeson-Lockwood, Peter Troell, Jessica Oyugi, Kim Lindblade, John E. Gimnig

Open Access Research

Studies on mosquito biting risk among migratory rice farmers in rural south-eastern Tanzania and development of a portable mosquito-proof hut

Johnson K. Swai, Marceline F. Finda, Edith P. Madumla, Godfrey F. Lingamba, Irene R. Moshi, Mohamed Y. Rafiq, Silas Majambere, Fredros O. Okumu

Open Access Research

Evidence of a multiple insecticide resistance in the malaria vector Anopheles funestus in South West Nigeria

Rousseau J. Djouaka, Seun M. Atoyebi, Genevieve M. Tchigossou, Jacob M. Riveron, Helen Irving, Romaric Akoton, Michael O. Kusimo, Adekunle A. Bakare, Charles S. Wondji

Open Access Research

Time series analysis of malaria in Afghanistan: using ARIMA models to predict future trends in incidence

Mohammad Y. Anwar, Joseph A. Lewnard, Sunil Parikh, Virginia E. Pitzer

Open Access Research

Community health workers adherence to referral guidelines: evidence from studies introducing RDTs in two malaria transmission settings in Uganda

Sham Lal, Richard Ndyomugenyi, Lucy Paintain, Neal D. Alexander, Kristian S. Hansen, Pascal Magnussen, Daniel Chandramohan, Siân E. Clarke

Open Access Research

Demographic and clinical profiles of Plasmodium falciparum and Plasmodium vivax patients at a tertiary care centre in southwestern India

Laura Chery, Jennifer N. Maki, Anjali Mascarenhas, Jayashri T. Walke, Pooja Gawas, Anvily Almeida, Mezia Fernandes, Marina Vaz, Rakesh Ramanan, Diksha Shirodkar, Maria Bernabeu, Suresh Kumar Manoharan, Ligia Pereira, Rashmi Dash, Ambika Sharma, Riaz Basha Shaik, Rimi Chakrabarti, Prasad Babar, John White III, Devaraja G. Mudeppa, Shiva Kumar, Wenyun Zuo, Kristen M. Skillman, Usheer Kanjee, Caeul Lim, Kathryn Shaw-Saliba, Ashwani Kumar, Neena Valecha, V. N. Jindal, Anar Khandeparkar, Pradeep Naik, Sunanda Amonkar, Manoj T. Duraisingh, Shripad Tuljapurkar, Joseph D. Smith, Nagesh Dubhashi, Roque G. W. Pinto, Maria Silveria, Edwin Gomes, Pradipsinh K. Rathod

Open Access Research

The hide and seek of Plasmodium vivax in West Africa: report from a large-scale study in Beninese asymptomatic subjects

Philippe Poirier, Cécile Doderer-Lang, Pascal S. Atchade, Jean-Philippe Lemoine, Marie-Louise Coquelin de l’Isle, Ahmed Abou-bacar, Alexander W. Pfaff, Julie Brunet, Lydia Arnoux, Elodie Haar, Denis Filisetti, Sylvie Perrotey, Nicodeme W. Chabi, Casimir D. Akpovi, Ludovic Anani, André Bigot, Ambaliou Sanni, Ermanno Candolfi

Open Access Research

Limitations of malaria reactive case detection in an area of low and unstable transmission on the Myanmar–Thailand border

Daniel M. Parker, Jordi Landier, Lorenz von Seidlein, Arjen Dondorp, Lisa White, Borimas Hanboonkunupakarn, Richard J. Maude, François H. Nosten

Open Access Research

Insight into k13-propeller gene polymorphism and ex vivo DHA-response profiles from Cameroonian isolates

Sandie Menard, Joëlle Njila Tchoufack, Christelle Ngou Maffo, Sandrine E. Nsango, Xavier Iriart, Luc Abate, Majoline Tchioffo Tsapi, Parfait H. Awono-Ambéné, Francis A. Abega Mekongo, Isabelle Morlais, Antoine Berry

Open Access Case study

Successful malaria elimination in the Ecuador–Peru border region: epidemiology and lessons learned

Lyndsay K. Krisher, Jesse Krisher, Mariano Ambuludi, Ana Arichabala, Efrain Beltrán-Ayala, Patricia Navarrete, Tania Ordoñez, Mark E. Polhemus, Fernando Quintana, Rosemary Rochford, Mercy Silva, Juan Bazo, Anna M. Stewart-Ibarra

Open Access Research

Provider and user acceptability of intermittent screening and treatment for the control of malaria in pregnancy in Malawi

Deborah Almond, Mwayi Madanitsa, Victor Mwapasa, Linda Kalilani-Phiri, Jayne Webster, Feiko ter Kuile, Lucy Paintain

Open Access Research

Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi

Matt Ravenhall, Ernest Diez Benavente, Mwapatsa Mipando, Anja T. R. Jensen, Colin J. Sutherland, Cally Roper, Nuno Sepúlveda, Dominic P. Kwiatkowski, Jacqui Montgomery, Kamija S. Phiri, Anja Terlouw, Alister Craig, Susana Campino, Harold Ocholla, Taane G. Clark

Open Access Research

Plasmodium malariae in the Colombian Amazon region: you don’t diagnose what you don’t suspect

Carlos Hernando Niño, Juan Ricardo Cubides, Paola Andrea Camargo-Ayala, Carlos Arturo Rodríguez-Celis, Teódulo Quiñones, Moisés Tomás Cortés-Castillo, Lizeth Sánchez-Suárez, Ricardo Sánchez, Manuel Elkin Patarroyo, Manuel Alfonso Patarroyo

Open Access Research

Evaluation of long-lasting microbial larvicide for malaria vector control in Kenya

Yaw A. Afrane, Nixon G. Mweresa, Christine L. Wanjala, Thomas M. Gilbreath III, Guofa Zhou, Ming-Chieh Lee, Andrew K. Githeko, Guiyun Yan

Open Access Research

Environmental determinants of malaria transmission in African villages

Noriko Endo, Elfatih A. B. Eltahir

Open Access Research

In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin

Abebe Genetu Bayih, Asongna Folefoc, Abu Naser Mohon, Scott Eagon, Marc Anderson, Dylan R. Pillai

Open Access Research

Perceptions on the effect of small electric fans on comfort inside bed nets in southern Ghana: a qualitative study

Mulako S. Jaeger, Olivier J. T. Briët, Joseph Keating, Collins K. Ahorlu, Joshua O. Yukich, Samuel Oppong, Peter Nardini, Constanze Pfeiffer

Open Access Research

Systematic review of the role of angiopoietin-1 and angiopoietin-2 in Plasmodium species infections: biomarkers or therapeutic targets?

Gerdie M. de Jong, Jasper J. Slager, Annelies Verbon, Jaap J. van Hellemond, Perry J. J. van Genderen

Open Access Research

Susceptibility of Anopheles gambiae to insecticides used for malaria vector control in Rwanda

Emmanuel Hakizimana, Corine Karema, Dunia Munyakanage, Gad Iranzi, John Githure, Jon Eric Tongren, Willem Takken, Agnes Binagwaho, Constantianus J. M. Koenraadt

Open Access Research

Emerging polymorphisms in falciparum Kelch 13 gene in Northeastern region of India

Neelima Mishra, Ram Suresh Bharti, Prashant Mallick, Om Prakash Singh, Bina Srivastava, Roma Rana, Sobhan Phookan, Hardev Prasad Gupta, Pascal Ringwald, Neena Valecha

Open Access Research

The return of chloroquine-susceptible Plasmodium falciparum malaria in Zambia

Sydney Mwanza, Sudhaunshu Joshi, Michael Nambozi, Justin Chileshe, Phidelis Malunga, Jean-Bertin Bukasa Kabuya, Sebastian Hachizovu, Christine Manyando, Modest Mulenga, Miriam Laufer

Open Access Research

Field effectiveness of microbial larvicides on mosquito larvae in malaria areas of Botswana and Zimbabwe

Mulamuli Mpofu, Piet Becker, Kaka Mudambo, Christiaan de Jager

Open Access Research

Economic evaluation of artesunate and three quinine regimens in the treatment of severe malaria in children at the Ebolowa Regional Hospital-Cameroon: a cost analysis

Daniel Ethe Maka, Andreas Chiabi, Bolaji Obadeyi, Evelyn Mah, Séraphin Nguefack, Pamela Nana, Wilfred Mbacham, Elie Mbonda

Open Access Research

Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei

Erin E. Milner, Jonathan Berman, Diana Caridha, Samuel P. Dickson, Mark Hickman, Patricia J. Lee, Sean R. Marcsisin, Lisa T. Read, Norma Roncal, Brian A. Vesely, Lisa H. Xie, Jing Zhang, Ping Zhang, Qigui Li

Open Access Research

Culex pipiens forms and urbanization: effects on blood feeding sources and transmission of avian Plasmodium

Josué Martínez-de la Puente, Martina Ferraguti, Santiago Ruiz, David Roiz, Ramón C. Soriguer, Jordi Figuerola

Open Access Research

Patterns and determinants of malaria risk in urban and peri-urban areas of Blantyre, Malawi

Don P. Mathanga, Atupele Kapito Tembo, Themba Mzilahowa, Andy Bauleni, Kondwani Mtimaukenena, Terrie E. Taylor, Clarissa Valim, Edward D. Walker, Mark L. Wilson

Open Access Research

A national health facility survey of malaria infection among febrile patients in Kenya, 2014

Sophie Githinji, Abdisalan M. Noor, Josephine Malinga, Peter M. Macharia, Rebecca Kiptui, Ahmeddin Omar, Kiambo Njagi, Ejersa Waqo, Robert W. Snow

Open Access Research

Plasmodium falciparum genotype and gametocyte prevalence in children with uncomplicated malaria in coastal Ghana

Ruth Ayanful-Torgby, Akua Oppong, Joana Abankwa, Festus Acquah, Kimberly C. Williamson, Linda Eva Amoah

Open Access Review

The economics of malaria control and elimination: a systematic review

Rima Shretta, Anton L. V. Avanceña, Arian Hatefi

Open Access Research

Using an intervention mapping approach for planning, implementing and assessing a community-led project towards malaria elimination in the Eastern Province of Rwanda

Chantal Marie Ingabire, Emmanuel Hakizimana, Fredrick Kateera, Alexis Rulisa, Bart Van Den Borne, Ingmar Nieuwold, Claude Muvunyi, Constantianus J. M. Koenraadt, Michele Van Vugt, Leon Mutesa, Jane Alaii

Open Access Research

Spatial and space–time distribution of Plasmodium vivax and Plasmodium falciparum malaria in China, 2005–2014

Samuel H. Hundessa, Gail Williams, Shanshan Li, Jinpeng Guo, Linping Chen, Wenyi Zhang, Yuming Guo

Open Access Research

Genetic evidence that the Makira region in northeastern Madagascar is a hotspot of malaria transmission

Benjamin L. Rice, Christopher D. Golden, Evelin Jean Gasta Anjaranirina, Carolina Mastella Botelho, Sarah K. Volkman, Daniel L. Hartl

Open Access Research

Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification

Samuel O. Oyola, Cristina V. Ariani, William L. Hamilton, Mihir Kekre, Lucas N. Amenga-Etego, Anita Ghansah, Gavin G. Rutledge, Seth Redmond, Magnus Manske, Dushyanth Jyothi, Chris G. Jacob, Thomas D. Otto, Kirk Rockett, Chris I. Newbold, Matthew Berriman, Dominic P. Kwiatkowski

Open Access Review

Malaria epidemiological research in the Republic of Congo

Felix Koukouikila-Koussounda, Francine Ntoumi

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