Ausgabe 1/2019
Inhalt (38 Artikel)
Transcranial direct current stimulation enhances theory of mind in Parkinson’s disease patients with mild cognitive impairment: a randomized, double-blind, sham-controlled study
Mauro Adenzato, Rosa Manenti, Ivan Enrici, Elena Gobbi, Michela Brambilla, Antonella Alberici, Maria Sofia Cotelli, Alessandro Padovani, Barbara Borroni, Maria Cotelli
Better survival in female SOD1-mutant patients with ALS: a study of SOD1-related natural history
Lu Tang, Yan Ma, Xiao-lu Liu, Lu Chen, Dong-sheng Fan
Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation
Shen-zhao Lu, Yong-shun Guo, Pei-zhou Liang, Shu-zhen Zhang, Shu Yin, Yan-qing Yin, Xiao-min Wang, Fei Ding, Xiao-song Gu, Jia-wei Zhou
Hydroxytryptamine transporter gene-linked polymorphic region (5HTTLPR) is associated with delusions in Alzheimer’s disease
Grazia D’Onofrio, Francesco Panza, Daniele Sancarlo, Michele Lauriola, Mariangela P. Dagostino, Giulia Paroni, Madia Lozupone, Antonio Mangiacotti, Paola Bisceglia, Carolina Gravina, Maria Urbano, Filomena Addante, Francesco Paris, Leandro Cascavilla, Antonio Greco, Davide Seripa
Constipation, deficit in colon contractions and alpha-synuclein inclusions within the colon precede motor abnormalities and neurodegeneration in the central nervous system in a mouse model of alpha-synucleinopathy
Lucia Rota, Carolina Pellegrini, Laura Benvenuti, Luca Antonioli, Matteo Fornai, Corrado Blandizzi, Antonino Cattaneo, Emanuela Colla
Molecular targets for modulating the protein translation vital to proteostasis and neuron degeneration in Parkinson’s disease
Zhi Dong Zhou, Thevapriya Selvaratnam, Ji Chao Tristan Lee, Yin Xia Chao, Eng-King Tan
Blocking meningeal lymphatic drainage aggravates Parkinson’s disease-like pathology in mice overexpressing mutated α-synuclein
Wenyan Zou, Tinglin Pu, Weixi Feng, Ming Lu, Ying Zheng, Renhong Du, Ming Xiao, Gang Hu
Enriched gestation activates the IGF pathway to evoke embryo-adult benefits to prevent Alzheimer’s disease
Enjie Liu, Qiuzhi Zhou, Ao-Ji Xie, Mengzhu Li, Shujuan Zhang, Hezhou Huang, Zhenyu Liuyang, Yali Wang, Bingjin Liu, Xiaoguang Li, Dongsheng Sun, Yuping Wei, Xiaochuan Wang, Qun Wang, Dan Ke, Xifei Yang, Ying Yang, Jian-Zhi Wang
Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration
José Aguareles, Juan Paraíso-Luna, Belén Palomares, Raquel Bajo-Grañeras, Carmen Navarrete, Andrea Ruiz-Calvo, Daniel García-Rincón, Elena García-Taboada, Manuel Guzmán, Eduardo Muñoz, Ismael Galve-Roperh
Correction to: Better survival in female SOD1-mutant patients with ALS: a study of SOD1-related natural history
Lu Tang, Yan Ma, Xiao-lu Liu, Lu Chen, Dong-sheng Fan
No association between Parkinson disease and autoantibodies against NMDA-type glutamate receptors
Franziska Hopfner, Stefanie H. Müller, Dagmar Steppat, Joanna Miller, Nele Schmidt, Klaus-Peter Wandinger, Frank Leypoldt, Daniela Berg, Andre Franke, Wolfgang Lieb, Lukas Tittmann, Monika Balzer-Geldsetzer, Simon Baudrexel, Richard Dodel, Ruediger Hilker-Roggendorf, Elke Kalbe, Jan Kassubek, Thomas Klockgether, Inga Liepelt-Scarfone, Brit Mollenhauer, Petra Neuser, Kathrin Reetz, Oliver Riedel, Claudia Schulte, Jörg B. Schulz, Annika Spottke, Alexander Storch, Claudia Trenkwalder, Hans-Ulrich Wittchen, Karsten Witt, Ullrich Wüllner, Günther Deuschl, Gregor Kuhlenbäumer
Cognitive decline is related to high blood glucose levels in older Chinese adults with the ApoE ε3/ε3 genotype
Qi Qiu, Xiang Lin, Lin Sun, Min-jie Zhu, Tao Wang, Jing-hua Wang, Guan-jun Li, Shi-fu Xiao, Xia Li
Loss of CREST leads to neuroinflammatory responses and ALS-like motor defects in mice
Cheng Cheng, Kan Yang, Xinwei Wu, Yuefang Zhang, Shifang Shan, Aaron Gitler, Anirvan Ghosh, Zilong Qiu
DNA repair deficiency in neuropathogenesis: when all roads lead to mitochondria
Luis Bermúdez-Guzmán, Alejandro Leal
Erythrocytic α-Synuclein as a potential biomarker for Parkinson’s disease
Chen Tian, Genliang Liu, Liyan Gao, David Soltys, Catherine Pan, Tessandra Stewart, Min Shi, Zhiying Xie, Na Liu, Tao Feng, Jing Zhang
NF-κB/c-Rel deficiency causes Parkinson’s disease-like prodromal symptoms and progressive pathology in mice
Edoardo Parrella, Arianna Bellucci, Vanessa Porrini, Marina Benarese, Annamaria Lanzillotta, Gaia Faustini, Francesca Longhena, Giulia Abate, Daniela Uberti, Marina Pizzi
Current progress of mitochondrial transplantation that promotes neuronal regeneration
Chu-Yuan Chang, Min-Zong Liang, Linyi Chen
Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Jia-Zhen Wu, Mustafa Ardah, Caroline Haikal, Alexander Svanbergsson, Meike Diepenbroek, Nishant N. Vaikath, Wen Li, Zhan-You Wang, Tiago F. Outeiro, Omar M. El-Agnaf, Jia-Yi Li
Clinical features and genetic spectrum in Chinese patients with recessive hereditary spastic paraplegia
Qiao Wei, Hai-Lin Dong, Li-Ying Pan, Cong-Xin Chen, Yang-Tian Yan, Rou-Min Wang, Hong-Fu Li, Zhi-Jun Liu, Qing-Qing Tao, Zhi-Ying Wu
How to spot ocular abnormalities in progressive supranuclear palsy? A practical review
Onanong Phokaewvarangkul, Roongroj Bhidayasiri
Alzheimer’s in a dish – induced pluripotent stem cell-based disease modeling
Sherida de Leeuw, Christian Tackenberg
Parkinson’s disease in China: a forty-year growing track of bedside work
Gen Li, Jianfang Ma, Shishuang Cui, Yixi He, Qin Xiao, Jun Liu, Shengdi Chen
The interplay of aging, genetics and environmental factors in the pathogenesis of Parkinson’s disease
Shirley Yin-Yu Pang, Philip Wing-Lok Ho, Hui-Fang Liu, Chi-Ting Leung, Lingfei Li, Eunice Eun Seo Chang, David Boyer Ramsden, Shu-Leong Ho
Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and multiple system atrophy
Chiara Maria Giulia De Luca, Antonio Emanuele Elia, Sara Maria Portaleone, Federico Angelo Cazzaniga, Martina Rossi, Edoardo Bistaffa, Elena De Cecco, Joanna Narkiewicz, Giulia Salzano, Olga Carletta, Luigi Romito, Grazia Devigili, Paola Soliveri, Pietro Tiraboschi, Giuseppe Legname, Fabrizio Tagliavini, Roberto Eleopra, Giorgio Giaccone, Fabio Moda
Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer’s disease and associated with CSF-TAU and FDG-PET
Oliver Goldhardt, Inanna Warnhoff, Igor Yakushev, Ilijana Begcevic, Hans Förstl, Viktor Magdolen, Antoninus Soosaipillai, Eleftherios Diamandis, Panagiotis Alexopoulos, Timo Grimmer
Bee venom phospholipase A2 ameliorates amyloidogenesis and neuroinflammation through inhibition of signal transducer and activator of transcription-3 pathway in Tg2576 mice
Hyeon Joo Ham, Sang-Bae Han, Jaesuk Yun, In Jun Yeo, Young Wan Ham, Se Hyun Kim, Pil-Hoon Park, Dong-Young Choi, Jin Tae Hong
Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the TDP-43G298S ALS mouse model
Hans-Peter Müller, David Brenner, Francesco Roselli, Diana Wiesner, Alireza Abaei, Martin Gorges, Karin M. Danzer, Albert C. Ludolph, William Tsao, Philip C. Wong, Volker Rasche, Jochen H. Weishaupt, Jan Kassubek
Beyond the synucleinopathies: alpha synuclein as a driving force in neurodegenerative comorbidities
Naomi P. Visanji, Anthony E. Lang, Gabor G. Kovacs
Xenografting of human umbilical mesenchymal stem cells from Wharton’s jelly ameliorates mouse spinocerebellar ataxia type 1
Pei-Jiun Tsai, Chang-Ching Yeh, Wan-Jhen Huang, Ming-Yuan Min, Tzu-Hao Huang, Tsui-Ling Ko, Pei-Yu Huang, Tien-Hua Chen, Sanford P. C. Hsu, Bing-Wen Soong, Yu-Show Fu
A longitudinal assessment of retinal function and structure in the APP/PS1 transgenic mouse model of Alzheimer’s disease
Dana Georgevsky, Stephanie Retsas, Newsha Raoufi, Olga Shimoni, S. Mojtaba Golzan
Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer’s disease and dementia with Lewy bodies
Ana Gámez-Valero, Jaume Campdelacreu, Dolores Vilas, Lourdes Ispierto, Ramón Reñé, Ramiro Álvarez, M. Pilar Armengol, Francesc E. Borràs, Katrin Beyer
Clinicopathologic characterization and abnormal autophagy of CSF1R-related leukoencephalopathy
Wo-Tu Tian, Fei-Xia Zhan, Qing Liu, Xing-Hua Luan, Chao Zhang, Liang Shang, Ben-Yan Zhang, Si-Jian Pan, Fei Miao, Jiong Hu, Ping Zhong, Shi-Hua Liu, Ze-Yu Zhu, Hai-Yan Zhou, Suya Sun, Xiao-Li Liu, Xiao-Jun Huang, Jing-Wen Jiang, Jian-Fang Ma, Ying Wang, Shu-Fen Chen, Hui-Dong Tang, Sheng-Di Chen, Li Cao
Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model
Luís Costa-Marques, Katrin Arnold, Marie-Christine Pardon, Christiane Leovsky, Samantha Swarbrick, Claire Fabian, Alexandra Stolzing
Lower serum expression of miR-181c-5p is associated with increased plasma levels of amyloid-beta 1–40 and cerebral vulnerability in normal aging
Marta Manzano-Crespo, Mercedes Atienza, Jose L. Cantero
Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models
Inger Lauritzen, Anaïs Bécot, Alexandre Bourgeois, Raphaëlle Pardossi-Piquard, Maria-Grazia Biferi, Martine Barkats, Fréderic Checler
Oscillation-specific nodal alterations in early to middle stages Parkinson’s disease
Xiaojun Guan, Tao Guo, Qiaoling Zeng, Jiaqiu Wang, Cheng Zhou, Chunlei Liu, Hongjiang Wei, Yuyao Zhang, Min Xuan, Quanquan Gu, Xiaojun Xu, Peiyu Huang, Jiali Pu, Baorong Zhang, Min-Ming Zhang
Detecting neurodegenerative pathology in multiple sclerosis before irreversible brain tissue loss sets in
Jeroen Van Schependom, Kaat Guldolf, Marie Béatrice D’hooghe, Guy Nagels, Miguel D’haeseleer
Microbiome changes: an indicator of Parkinson’s disease?
Caroline Haikal, Qian-Qian Chen, Jia-Yi Li