Skip to main content

Trials

Ausgabe 1/2006

Inhalt (35 Artikel)

Open Access Study protocol

The internal thoracic artery skeletonization study: A paired, within-patient comparison [NCT00265499]

Munir Boodhwani, Howard J Nathan, B Khanh Lam, Fraser D Rubens

Open Access Study protocol

Prophylactic antibiotic for prevention of posttraumatic meningitis after traumatic pneumocephalus: design and rationale of a placebo-controlled randomized multicenter trial [ISRCTN71132784]

Behzad Eftekhar, Mohammad Ghodsi, Azar Hadadi, Mousa Taghipoor, Samira Zabihyan Sigarchi, Vafa Rahimi-Movaghar, Ehsan Sherafat Kazemzadeh, Babak Esmaeeli, Farideh Nejat, Alireza Yalda, Ebrahim Ketabchi

Open Access Commentary

Flaws in design, analysis and interpretation of Pfizer's antifungal trials of voriconazole and uncritical subsequent quotations

Karsten J Jørgensen, Helle Krogh Johansen, Peter C Gøtzsche

Open Access Study protocol

Multifactorial day hospital intervention to reduce falls in high risk older people in primary care: a multi-centre randomised controlled trial [ISRCTN46584556]

Tahir Masud, Carol Coupland, Avril Drummond, John Gladman, Denise Kendrick, Tracey Sach, Rowan Harwood, Pradeep Kumar, Rob Morris, Rachael Taylor, Jane Youde, Simon Conroy

Open Access Editorial

Lead editorial: Trials – using the opportunities of electronic publishing to improve the reporting of randomised trials

Douglas G Altman, Curt D Furberg, Jeremy M Grimshaw, Peter M Rothwell

Open Access Study protocol

Multifactorial approach and superior treatment efficacy in renal patients with the aid of nurse practitioners. Design of The MASTERPLAN Study [ISRCTN73187232]

Arjan D van Zuilen, Ingeborgh van der Tweel, Peter J Blankestijn, Michiel L Bots, Marjolijn van Buren, Marc AGJ ten Dam, Karin AH Kaasjager, Peter JG van de Ven, Gerald Vervoort, Louis-Jean Vleming, Gerry Ligtenberg, Jack FM Wetzels

Open Access Research

What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies

Alison M McDonald, Rosemary C Knight, Marion K Campbell, Vikki A Entwistle, Adrian M Grant, Jonathan A Cook, Diana R Elbourne, David Francis, Jo Garcia, Ian Roberts, Claire Snowdon

Open Access Study protocol

The effects of organic nitrates on osteoporosis: a randomized controlled trial [ISRCTN94484747]

Sophie A Jamal, Celeste J Hamilton, Dennis Black, Steven R Cummings

Open Access Study protocol

Duodenum preserving pancreatectomy in chronic pancreatitis: Design of a randomized controlled trial comparing two surgical techniques [ISRCTN50638764]

Jörg Köninger, Christoph M Seiler, Moritz N Wente, Margot A Reidel, Emre Gazyakan, Ulrich Mansmann, Michael W Müller, Helmut Friess, Markus W Büchler

Open Access Study protocol

Double blind, randomized controlled trial, to evaluate the effectiveness of a controlled nitric oxide releasing patch versus meglumine antimoniate in the treatment of cutaneous leishmaniasis [NCT00317629]

Sandra Y Silva, Ligia C Rueda, Marcos López, Iván D Vélez, Christian F Rueda-Clausen, Daniel J Smith, Gerardo Muñoz, Hernando Mosquera, Federico A Silva, Adriana Buitrago, Holger Díaz, Patricio López-Jaramillo

Open Access Research

Increasing participation of cancer patients in randomised controlled trials: a systematic review

Catriona Mc Daid, Zoé Hodges, Debra Fayter, Lisa Stirk, Alison Eastwood

Open Access Research

Lessons and implications from a mass immunization campaign in squatter settlements of Karachi, Pakistan: an experience from a cluster-randomized double-blinded vaccine trial [NCT00125047]

Mohammad Imran Khan, Rion Leon Ochiai, Hasan Bin Hamza, Shah Muhammad Sahito, Muhammad Atif Habib, Sajid Bashir Soofi, Naveed Sarwar Bhutto, Shahid Rasool, Mahesh K Puri, Mohammad Ali, Shafi Mohammad Wasan, Mohammad Jawed Khan, Remon Abu-Elyazeed, Bernard Ivanoff, Claudia M Galindo, Tikki Pang, Allan Donner, Lorenz von Seidlein, Camilo J Acosta, John D Clemens, Shaikh Qamaruddin Nizami, Zulfiqar A Bhutta

Open Access Study protocol

I Design of the Primary Prevention Parameters Evaluation (PREPARE) trial of implantablecardioverter defibrillators to reduce patient morbidity [NCT00279279]

Bruce L Wilkoff, Richard Stern, Brian Williamson, Mark Wathen, Keith Holloman, Ann Fieberg, Mark Brown

Open Access Study protocol

A randomized clinical trial of unfractioned heparin for treatment of sepsis (the HETRASE study): design and rationale [NCT00100308]

Fabián Jaimes, Gisela De La Rosa, Clara Arango, Fernando Fortich, Carlos Morales, Daniel Aguirre, Pablo Patiño

Open Access Study protocol

Comparison of Venae Sectio vs. modified Seldinger Technique for Totally Implantable Access Ports; Portas-trial [ISRCTN:52368201]

P Knebel, B Fröhlich, H-P Knaebel, P Kienle, S Luntz, MW Buchler, CM Seiler

Open Access Letter

CRASH2 in Germany [ISRCTN86750102]

CH Chung, A Freiberger, M Kalkum, SP Luntz, H Shakur, CM Seiler

Open Access Study protocol

Sub-vastus approach versus the medial parapatellar approach in primary total knee: a randomised controlled trial [ISRCTN44544446]

Stephen Bridgman, Gayle Walley, Gilbert MacKenzie, Darren Clement, David Griffiths, Nicola Maffulli

Open Access Study protocol

Double blind randomized placebo-controlled trial on the effects of testosterone supplementation in elderly men with moderate to low testosterone levels: design and baseline characteristics [ISRCTN23688581]

Hamid Reza Nakhai Pour, Marielle H Emmelot-Vonk, Marja Sukel-Helleman, Harald JJ Verhaar, Diederick E Grobbee, Yvonne T van der Schouw

Open Access Research

Factors associated with compliance and non-compliance by physicians in a large-scale randomized clinical trial

Koji Oba, Satoshi Morita, Mahbubur Rahman, Junichi Sakamoto

Open Access Study protocol

Protocol design and current status of CLIVIT: a randomized controlled multicenter relevance trial comparing clips versus ligatures in thyroid surgery

CM Seiler, BE Fröhlich, JA Veit, E Gazyakan, MN Wente, C Wollermann, A Deckert, S Witte, N Victor, MW Buchler, HP Knaebel

Open Access Study protocol

A randomized, double blind, cross-over, placebo-controlled clinical trial to assess the effects of Candesartan on the insulin sensitivity on non diabetic, non hypertense subjects with dysglyce mia and abdominal obesity. "ARAMIA"

Patricio López-Jaramillo, Lina P Pradilla, Vicente Lahera, Federico A Silva Sieger, Christian F Rueda-Clausen, Gustavo A Márquez

Open Access Study protocol

Hemicraniectomy after middle cerebral artery infarction with life-threatening Edema trial (HAMLET). Protocol for a randomised controlled trial of decompressive surgery in space-occupying hemispheric infarction

Jeannette Hofmeijer, G Johan Amelink, Ale Algra, Jan van Gijn, Malcolm R Macleod, L Jaap Kappelle, H Bart van der Worp

Open Access Methodology

Selecting patients for randomized trials: a systematic approach based on risk group

Andrew J Vickers, Barry S Kramer, Stuart G Baker

Open Access Study protocol

Acetylsalicylic acid as an adjuvant therapy for schizophrenia

Wijnand Laan, Jean-Paul Selten, René S Kahn, Anne-Margriet Huisman, Cobi J Heijnen, Diederick E Grobbee, Huibert Burger

Open Access Study protocol

Fracture risk and the use of a diuretic (indapamide sr) ± perindopril: a substudy of the Hypertension in the Very Elderly Trial (HYVET)

Christopher J Bulpitt, Ruth Peters, Jan A Staessen, Lutgarde Thijs, Marie-Christine De Vernejoul, Astrid E Fletcher, Nigel S Beckett

Open Access Research

Financial considerations in the conduct of multi-centre randomised controlled trials: evidence from a qualitative study

Claire Snowdon, Diana R Elbourne, Jo Garcia, Marion K Campbell, Vikki A Entwistle, David Francis, Adrian M Grant, Rosemary C Knight, Alison M McDonald, Ian Roberts

Open Access Research

Comparison of the efficacy and safety of rosuvastatin 10 mg and atorvastatin 20 mg in high-risk patients with hypercholesterolemia – Prospective study to evaluate the Use of Low doses of the Statins Atorvastatin and Rosuvastatin (PULSAR)

Michael B Clearfield, John Amerena, Jean-Pierre Bassand, Hugo R Hernández García, Sam S Miller, Froukje FM Sosef, Michael K Palmer, Brian S Bryzinski