Background
Psychotic disorders are often chronic and severe. Schizophrenia is a psychotic disorder that affects about 0.5% of the population [
1] and has a lifetime prevalence of 1% [
2]. Personality can affect symptoms and social functioning in schizophrenia [
3]. Relationships have been observed between certain personality traits and the subsequent development of psychotic symptoms, psychosis and schizophrenia [
4‐
6]. There is also studies reporting associations between individual differences in personality traits in patients with schizophrenia and symptom severity, occupational functioning, substance use, violent behavior, social isolation, and suicidal ideation, for review see [
7]. This makes personality an important aspect of psychosis and schizophrenia. Several studies have investigated personality in schizophrenia [
8‐
11]. However, there is a dearth of previous studies that have analysed stability of personality traits in patients with psychotic disorder. Personality is generally thought of as stable, although changes occur, especially during childhood and adolescence but also during adulthood, especially late in life [
12]. To date, three studies have used various Five-Factor Model (FFM) questionnaires, namely NEO-Personality Inventory (NEO-PI), NEO-Five Factor Inventory (NEO-FFI), and NEO-Personality Inventory Revised (NEO-PI-R) and one that used the 168 item version of the Minnesota Multiphasic Personality Inventory (MMPI-168) to assess stability of personality traits in this patient group. Kentros et al. (1997), investigated 21 patients with schizophrenia and schizoaffective disorders (mean age 34 years) over a six-month period using test-retest correlations [
13]. They found strong correlations for Neuroticism, Extraversion, Openness and Conscientiousness whereas for Agreeableness the strength of the correlation was moderate. The authors concluded that FFM personality traits remain stable over time, despite fluctuations in psychotic positive symptoms.
In another previous study [
14], the mean-level of stability of personality traits was investigated in 79 patients with first-episode psychosis (mean age 24 years) over a three-month period. Statistical analysis using paired
t-test showed no significant differences between baseline and follow-up, indicating that FFM personality traits remained stable over time.
Boyette et al. [
15] investigated three-year temporal stability of FFM traits in 91 patients with non-affective psychotic disorders (mean age 32 years) with a maximum duration of illness of ten years and 32 control subjects without a diagnosis of psychotic illness [
15]. An evaluation of mean-level fluctuations among patients and controls revealed no significant differences between baseline and follow-up, with the exception of Conscientiousness among patients. Using Spearman correlations the relationships between baseline and follow-up were moderate to strong (rho 0.51–0.68) and moderate to very strong (rho 0.57–0.90) among patients and controls, respectively. Results showed that psychotic symptoms have a limited effect on the stability of FFM traits in patients with psychotic disorders.
Horan and colleges analysed intra-class correlations (ICCs) of the MMPI personality traits Neuroticism, Denial of somatic complaints, Cynicism, Psychopathic tendencies and Psychotic ideation among patients with schizophrenia spectrum disorders (mean age 23 years) and control subjects investigated three times during a period of 15 months [
16]. These authors found ICCs between 0.29 to 0.55 for patients and 0.66 to 0.83 for controls, indicating less stability among patients than controls. Nonetheless, considerable stability of personality traits was indicated among patients.
Swedish universities scales of personality (SSP) is an established personality instrument, preferably used in Sweden and other countries in northern Europe since 17 years. It is an elaboration of the instrument Karolinska Scales of Personality (KSP), which was designed to measure stable personality traits related to psychopathology [
17,
18]. SSP has been described in detail previously [
19]. In contrast to other personality instruments translated into Swedish, such as the NEO-PI-R or the Temperament and Character Inventory (TCI) [
20], SSP can be used for free in the clinic. SSP gives comparison possibilities versus the general population for 13 different clinically relevant personality aspects. This together with its relatively short format (91 items, compared to 238–240 items for the full NEO and TCI questionnaires) has made it common in clinical practice in Sweden. SSP has been subjected to factor analysis and comprise the following higher order factors: Neuroticism, Aggressiveness and Extraversion [
19,
21]. When compared with the FFM using NEO-PI-R Aluoja and coworkers (2009) described as an overall pattern, although with some exceptions, that SSP neuroticism-related scales had their highest loadings on NEO Neuroticism, SSP extraversion-related scales on NEO Extraversion and the Aggression-related scales on NEO Agreeableness [
21]. However, SSP has until recently not been used among psychotic patients within research [
22]. Also SSPs predecessor KSP has only sparsely been evaluated among patients with psychosis [
23,
24], although both SSP and KSP have been frequently used among other psychiatric patient categories.
Three previous studies have investigated stability of personality traits measured using the SSP at two different time-points. A Swedish research team investigated the impact of internet-based cognitive behaviour therapy (ICBT) on personality traits [
25]. In a randomized controlled trial participants with a mean age of 39 years were distributed to 12 weeks of ICBT (
n = 40) or to a basic attention control condition (
n = 41). During the latter condition patients scored essentially similar at baseline and at follow-up (z-score deviation < 0.21 in all 13 SSP-scales). However, ICBT patients scored lower on neuroticism-related scales with z-scores deviating up to 0.48 (Psychic trait anxiety) and 0.52 (Somatic trait anxiety) in the second compared to the first assessment, whereas for the non-neuroticism-related scales no difference exceeded z = 0.25.
Estonian researchers investigated 107 patients (mean age 34 years) with panic disorder before and after 12 weeks of treatment with escitalopram [
26]. There were no significant differences between SSP baseline and post-treatment scale scores, although almost all scores being abnormal from the beginning were less deviant after treatment. The largest changes occurred for the neuroticism-related scales Somatic trait anxiety (z = 0.67), Psychic trait anxiety (z = 0.53) and Stress susceptibility (z = 0.48), whereas for the remaining SSP scales the differences were below z = 0.35.
In an eight weeks follow-up study possible effects of mechanical massage, mental training programmes or a combination of interventions on healthy employees with a mean age of 48 years were examined by using the SSP personality traits Somatic Trait Anxiety (STA), Psychic Trait Anxiety (PsTA), Stress Susceptibility (SS), Detachment (D) and Social Desirability (SD) [
27]. Employees were randomly distributed to one of five intervention groups; Massage and mental training, Massage, Mental training, Pause and Control with 13 to 18 participants in each group at the end of the trial. SSP mean z-score deviations between baseline and eight weeks of intervention were for STA − 0.19, PsTA -0.09, SS -0.09, D 0.17 and SD 0.17, and with no z-score deviation exceeding 0.4 in the various small intervention groups.
Stability in personality traits in patients with psychotic disorder has not previously been investigated at time intervals longer than three years and with participants with a mean age above 34 years. In the present study we investigated outpatients diagnosed with a psychotic disorder and non-psychotic control subjects on two occasions five years apart, with a mean age at the first investigation of about 40 years. We used SSP [
19], a questionnaire not previously assessed for stability measures of personality for this time frame and in this patient category.
We aimed to investigate firstly, whether personality traits were stable over a five-year period in a sample of patients with psychosis; and secondly whether patients with psychosis differed from non-psychotic individuals.
Results
Characterisation of subjects
Characteristics of the subjects are shown in Table
1. There were eight (22%) female and 28 (78%) male patients with psychotic disorder and 29 (38%) women and 47 (62%) men among the non-psychotic subjects (chi squared = 2.130,
p = 0.144). The mean age (SD; range) was at baseline among female patients 37.5 (8.2; 25–50), male patients 36.9 (7.5; 24–50), female control subjects 40.8 (7.4; 24–50), and male control subjects 41.2 (8.1; 23–53) years, respectively. No significant case-control differences with regard to age or gender was found (Table
1). Patients had a lower level of functioning, lower verbal IQ and tended to be less educated (Table
1). Mean age at onset of illness was 24.2 years. Patients were diagnosed with psychosis not otherwise specified (
n = 3), schizoaffective disorder (
n = 7) and schizophrenia (
n = 26).
Table 1
Characteristics of patients and controls
Gender (n, women/men) | 8/28 | 8/28 | 29/47 | 29/47 |
Age (year) | 39.4 | 44.4 | 41.1 | 47.5§ |
Education (year) | 12.6 | NA | 14.0§ | NA |
WAIS verbal IQ | 87.3 | NA | 103.0*** | NA |
GAF | 49.2 | 48.3 | 87.3*** | 83.9*** |
SANS composite score | 28.9 | 33.4 | NA | NA |
SAPS composite score | 10.0 | 11.1 | NA | NA |
Medication (mg, CPZ-equivalents) | 208.9 | 263.3 | NA | NA |
Medication-no antipsychotics (n) | 4 | 5 | NA | NA |
Medication-2nd gen antipsychotics (n) | 14 | 15 | NA | NA |
Medication-1st gen antipsychotics (n) | 16 | 9 | NA | NA |
Medication-1st and 2nd gen antipsychotics (n) | 2 | 7 | NA | NA |
Internal consistency
The attrition rate was among male cases 0.72, female cases 0.77, non-psychotic men 0.53 and non-psychotic women 0.54. Among the 71 patients who did not participate at follow-up the reasons were: declined to participate or no contact (n = 54), dead (n = 15), changed residence to a region far away or emigrated (n = 2). Reasons for drop-out among the 66 controls were: no available time (n = 5), declined to participate or no contact (n = 54), changed residence to a region far away or emigrated (n = 7). Subjects participating and not participating at follow-up did not significantly differ at baseline with regard to gender, age, verbal IQ, GAF, negative or positive psychotic symptomatology, chlorpromazine equivalent dose of antipsychotic medication or any of the SSP personality traits.
Internal consistency of the 13 SSP-scales was evaluated at both baseline and follow-up for patients and non-psychotic individuals separately (Table
2). Consistencies were above 0.70 for 54% of the patients and 82% of the non-psychotic individuals. Consistencies were above 0.60 for 81% of the patients and 96% of the non-psychotic individuals. Among patients Somatic Trait Anxiety, Stress Susceptibility, Impulsiveness, Detachment, Social Desirability, Embitterment and Mistrust and among non-psychotic individuals Lack of Assertiveness and Social Desirability was below 0.70 for at least one of the time-points.
Table 2
Swedish Scales of Personality (SSP) internal consistency data given as Cronbach’s α for psychotic patients (n = 36) and control subjects (n = 76) at baseline and follow-up
Somatic Trait Anxiety | 0.45 | 0.52 | 0.72 | 0.74 |
Psychic Trait Anxiety | 0.75 | 0.73 | 0.85 | 0.77 |
Stress Susceptibility | 0.69 | 0.63 | 0.80 | 0.78 |
Lack of Assertiveness | 0.77 | 0.77 | 0.65 | 0.71 |
Impulsiveness | 0.64 | 0.59 | 0.74 | 0.76 |
Adventure Seeking | 0.72 | 0.74 | 0.82 | 0.84 |
Detachment | 0.79 | 0.60 | 0.77 | 0.75 |
Social Desirability | 0.66 | 0.54 | 0.64 | 0.56 |
Embitterment | 0.56 | 0.66 | 0.78 | 0.77 |
Trait Irritability | 0.76 | 0.80 | 0.79 | 0.77 |
Mistrust | 0.78 | 0.68 | 0.86 | 0.84 |
Verbal Trait Aggression | 0.80 | 0.72 | 0.73 | 0.74 |
Physical Trait Aggression | 0.80 | 0.80 | 0.87 | 0.84 |
Effect by time on mean differences
For an overview of the personality data at baseline and follow-up, see Table
3. Controls showed nominally higher estimates of Social Desirability and lower estimates of Psychic Trait Anxiety, Impulsiveness, Adventure Seeking, Embitterment, Trait Irritability, Mistrust, Verbal Trait Aggression and Physical Trait Aggression at follow-up compared to baseline. Among patients Adventure Seeking and Trait Irritability showed a similar pattern as in the non-psychotic individuals. However, after correction for multiple testing and taking covariates into account, MANCOVA within-subjects analysis of the means did not show any significant effect of time, interaction time * age, interaction time * diagnosis, interaction time * gender, or interaction time * diagnosis * gender (all Wilk’s lambda> 0.825, all
p > 0.117).
Table 3
Swedish universities Scales of Personality (SSP) raw scores (mean [standard deviation]) and 95% confidence interval (CI) of the difference between baseline and follow-up in patients with psychotic illness and non-psychotic controls
| | | Somatic Trait Anxiety | Psychic Trait Anxiety | Stress Susceptibility |
| | N | Baseline | Follow-up | CI | Baseline | Follow-up | CI | Baseline | Follow-up | CI |
ALL | Patient | 36 | 39.4 (7.7) | 44.4 (7.8) | −0.25 – 0.15 | 2.08 (0.48) | 2.13 (0.53) | −0.09 – 0.27 | 2.45 (0.62) | 2.36 (0.61) | −0.19 – 0.16 |
| Control | 76 | 41.1 (7.8) | 47.5 (7.8) | −0.06 – 0.12 | 1.58 (0.46) | 1.55 (0.45) | 0.11–0.26 | 1.66 (0.50) | 1.48 (0.39) | −0.05 – 0.14 |
ALL | Men | 75 | 40.7 (7.9) | 46.5 (8.0) | −0.14 – 0.08 | 1.68 (0.48) | 1.71 (0.56) | 0.04–0.22 | 1.92 (0.68) | 1.79 (0.66) | −0.06 – 0.14 |
| Women | 37 | 40.1 (7.7) | 46.4 (7.9) | −0.08 – 0.21 | 1.74 (0.52) | 1.78 (0.53) | 0.07–0.34 | 1.90 (0.60) | 1.70 (0.55) | −0.17 – 0.16 |
PATIENT | Men | 28 | 39.9 (7.5) | 44.9 (7.6) | −0.39 – 0.09 | 2.05 (0.39) | 2.19 (0.51) | −0.17 – 0.24 | 2.47 (0.60) | 2.43 (0.52) | −0.24 – 0.17 |
| Women | 8 | 37.5 (8.2) | 42.6 (8.2) | 0.02–0.55 | 2.21 (0.71) | 1.93 (0.57) | −0.17 – 0.74 | 2.38 (0.71) | 2.09 (0.84) | −0.40 – 0.51 |
CONTROL | Men | 47 | 41.2 (8.1) | 47.5 (8.0) | −0.06 – 0.14 | 1.47 (0.39) | 1.43 (0.36) | 0.10–0.28 | 1.60 (0.49) | 1.41 (0.37) | −0.02 – 0.20 |
| Women | 29 | 40.8 (7.4) | 47.5 (7.5) | −0.16 – 0.18 | 1.75 (0.71) | 1.74 (0.52) | 0.04–0.33 | 1.77 (0.51) | 1.59 (0.40) | −0.21 – 0.17 |
| | Lack of Assertiveness | Impulsiveness | Adventure Seeking |
| | Baseline | Follow-up | CI | Baseline | Follow-up | CI | Baseline | Follow-up | CI |
ALL | Patient | 2.46 (0.55) | 2.47 (0.53) | −0.13 – 0.28 | 2.33 (0.52) | 2.25 (0.51) | −0.07 – 0.23 | 2.50 (0.58) | 2.38 (0.61) | 10.04–0.29 |
| Control | 1.87 (0.47) | 1.82 (0.44) | −0.04 – 0.11 | 2.30 (0.46) | 2.19 (0.47) | 0.02–0.20 | 2.53 (0.52) | 2.39 (0.51) | 0.07–0.22 |
ALL | Men | 2.06 (0.61) | 2.02 (0.58) | −0.06 – 0.16 | 2.23 (0.47) | 2.15 (0.47) | −0.01 – 0.17 | 2.57 (0.58) | 2.42 (0.56) | 0.06–0.25 |
| Women | 2.04 (0.46) | 2.05 (0.53) | −0.07 – 0.15 | 2.48 (0.45) | 2.34 (0.49) | 0.01–0.28 | 2.42 (0.43) | 2.33 (0.50) | −0.01 – 0.21 |
PATIENT | Men | 2.48 (0.60) | 2.52 (0.46) | −0.18 – 0.33 | 2.28 (0.51) | 2.21 (0.52) | −0.12 – 0.24 | 2.52 (0.62) | 2.34 (0.65) | −0.02 – 0.38 |
| Women | 2.36 (0.38) | 2.30 (0.76) | −0.21 – 0.35 | 2.52 (0.51) | 2.38 (0.48) | −0.22 – 0.49 | 2.46 (0.39) | 2.54 (0.46) | −0.33 – 0.19 |
CONTROL | Men | 1.81 (0.47) | 1.72 (0.41) | −0.06 – 0.13 | 2.19 (0.44) | 2.11 (0.44) | −0.02 – 0.20 | 2.61 (0.55) | 2.47 (0.51) | 0.04–0.24 |
| Women | 1.96 (0.45) | 1.98 (0.44) | −0.09 – 0.16 | 2.47 (0.44) | 2.33 (0.50) | −0.00 – 0.30 | 2.41 (0.44) | 2.27 (0.50) | 0.02–0.27 |
| | Detachment | Social Desirability | Embitterment |
| | Baseline | Follow-up | CI | Baseline | Follow-up | CI | Baseline | Follow-up | CI |
ALL | Patient | 2.77 (0.53) | 2.83 (0.45) | −0.14 – 0.17 | 2.77 (0.53) | 2.83 (0.45) | −0.24 – 0.13 | 2.23 (0.50) | 2.22 (0.55) | −0.15 – 0.17 |
| Control | 2.83 (0.37) | 2.92 (0.35) | −0.02 – 0.12 | 2.83 (0.37) | 2.92 (0.35) | −0.15 - -0.03 | 1.60 (0.41) | 1.47 (0.40) | 0.05–0.20 |
ALL | Men | 2.80 (0.43) | 2.88 (0.39) | −0.05 – 0.12 | 2.80 (0.43) | 2.88 (0.39) | −0.16 – 0.00 | 1.82 (0.52) | 1.72 (0.59) | 0.01–0.20 |
| Women | 2.82 (0.42) | 2.90 (0.38) | −0.09 – 0.18 | 2.82 (0.42) | 2.90 (0.38) | −0.21 – 0.06 | 1.75 (0.56) | 1.69 (0.59) | −0.06 – 0.18 |
PATIENT | Men | 2.82 (0.56) | 2.80 (0.46) | −0.14 – 0.20 | 2.82 (0.56) | 2.80 (0.46) | −0.18 – 0.21 | 2.23 (0.44) | 2.23 (0.57) | −0.20 – 0.20 |
| Women | 2.61 (0.42) | 2.91 (0.44) | −0.51 – 0.48 | 2.61 (0.42) | 2.91 (0.44) | −0.87 – 0.26 | 2.23 (0.69) | 2.17 (0.51) | −0.22 – 0.34 |
CONTROL | Men | 2.79 (0.34) | 2.93 (0.34) | −0.05 – 0.13 | 2.79 (0.34) | 2.93 (0.34) | −0.21 - − 0.07 | 1.58 (0.39) | 1.42 (0.34) | 0.08–0.25 |
| Women | 2.88 (0.41) | 2.90 (0.36) | -0.07 – 0.20 | 2.88 (0.41) | 2.90 (0.36) | −0.12 – 0.09 | 1.62 (0.45) | 1.56 (0.47) | −0.08 – 0.20 |
| | Trait Irritability | Mistrust | | |
| | Baseline | Follow-up | CI | Baseline | Follow-up | CI | | |
ALL | Patient | 2.35 (0.57) | 2.13 (0.57) | 0.03–0.40 | 2.26 (0.58) | 2.26 (0.52) | −0.13 – 0.15 | | |
| Control | 2.21 (0.48) | 2.03 (0.49) | 0.09–0.26 | 1.75 (0.50) | 1.60 (0.47) | 0.06–0.24 | | |
ALL | Men | 2.26 (0.49) | 2.04 (0.53) | 0.12–0.31 | 1.97 (0.56) | 1.86 (0.57) | 0.02–0.21 | | |
| Women | 2.24 (0.55) | 2.11 (0.50) | −0.03 – 0.29 | 1.81 (0.59) | 1.72 (0.58) | −0.03 – 0.21 | | |
PATIENT | Men | 2.36 (0.56) | 2.16 (0.53) | 0.01–0.38 | 2.28 (0.58) | 2.25 (0.53) | −0.14 – 0.21 | | |
| Women | 2.32 (0.66) | 2.04 (0.74) | −0.37 – 0.94 | 2.20 (0.62) | 2.29 (0.55) | −0.24 – 0.07 | | |
CONTROL | Men | 2.20 (0.45) | 1.97 (0.51) | 0.11–0.34 | 1.79 (0.47) | 1.62 (0.47) | 0.05–0.28 | | |
| Women | 2.22 (0.48) | 2.13 (0.43) | −0.05 – 0.22 | 1.70 (0.54) | 1.56 (0.49) | −0.01 -0.29 | | |
| | Verbal Trait Aggression | Physical Trait Aggression | | |
| | Baseline | Follow-up | CI | Baseline | Follow-up | CI | | |
ALL | Patient | 2.01 (0.64) | 2.00 (0.55) | −0.19 – 0.20 | 1.71 (0.57) | 1.84 (0.60) | −0.31 – 0.07 | | |
| Control | 2.15 (0.47) | 1.96 (0.46) | 0.10–0.28 | 1.93 (0.57) | 1.67 (0.54) | 0.17–0.35 | | |
ALL | Men | 2.12 (0.53) | 2.02 (0.58) | −0.01 – 0.21 | 1.92 (0.60) | 1.81 (0.59) | 0.00–0.23 | | |
| Women | 2.07 (0.55) | 1.88 (0.43) | 0.04–0.33 | 1.73 (0.53) | 1.55 (0.46) | 0.01–0.33 | | |
PATIENT | Men | 2.03 (0.62) | 2.07 (0.58) | −0.26 – 0.18 | 1.76 (0.59) | 1.86 (0.66) | −0.33 – 0.13 | | |
| Women | 1.95 (0.74) | 1.79 (0.38) | −0.37 – 0.69 | 1.54 (0.47) | 1.74 (0.39) | −0.57 – 0.16 | | |
CONTROL | Men | 2.18 (0.46) | 2.00 (0.48) | 0.07–0.31 | 2.02 (0.58) | 1.78 (0.55) | 0.14–0.35 | | |
| Women | 2.10 (0.50) | 1.91 (0.44) | 0.04–0.34 | 1.78 (0.54) | 1.50 (0.47) | 0.11–0.44 | | |
Effect by time on interpersonal correlations
Within-subjects correlations are shown in Table
4. For patients the rank-order correlations (rho) between the two testing time-points varied between 0.30 and 0.68, with the lowest correlations for Somatic Trait Anxiety (0.30) and Social Desirability (0.38) and the highest for Mistrust (0.68). Among non-psychotic individuals the correlations varied between 0.54 (Stress Susceptibility) and 0.75 (Adventure Seeking). Linear correlations (r) and ICCs were of a similar magnitude (Table
4). The MANCOVA analysis of the test-retest correlations was significant with regard to diagnosis (Wilk’s lambda 0.791,
p = 0.036) but not to gender (Wilk’s lambda 0.825,
p = 0.114), age (Wilk’s lambda 0.848,
p = 0.222) or interaction between diagnosis and gender (Wilk’s lambda 0.826,
p = 0.119). In post-hoc analyses ANCOVAs were performed for each of the SSP scales. In the 13 post-hoc ANCOVAs of the test-retest correlations the following nominal differences was found: age and Detachment (
F = 4.2,
p = 0.044), age and Social Desirability (
F = 4,9,
p = 0.029), diagnosis and Detachment (
F = 11.3,
p = 0.001), gender and Social Desirability (
F = 4.5,
p = 0.035), gender * diagnosis and Detachment (
F = 4.3,
p = 0.040), and gender * diagnosis and Social Desirability (
F = 5.8,
p < 0.018).
Table 4
Correlations between baseline and five year follow-up assessments of the Swedish universities Scales of Personality (SSP) in psychotic patients (n = 36) and control subjects (n = 76)
Somatic Trait Anxiety | 0.30 | 0.57 | 0.31 | 0.64 | 0.30 | 0.64 | 0.31 | 0.64 |
Psychic Trait Anxiety | 0.61 | 0.73 | 0.63 | 0.75 | 0.62 | 0.73 | 0.62 | 0.67 |
Stress Susceptibility | 0.59 | 0.54 | 0.53 | 0.57 | 0.53 | 0.57 | 0.54 | 0.57 |
Lack of Assertiveness | 0.48 | 0.64 | 0.56 | 0.70 | 0.56 | 0.70 | 0.56 | 0.70 |
Impulsiveness | 0.62 | 0.64 | 0.62 | 0.67 | 0.62 | 0.67 | 0.62 | 0.65 |
Adventure Seeking | 0.61 | 0.75 | 0.67 | 0.79 | 0.67 | 0.79 | 0.66 | 0.76 |
Detachment | 0.67 | 0.63 | 0.69 | 0.71 | 0.67 | 0.71 | 0.68 | 0.71 |
Social Desirability | 0.38 | 0.70 | 0.38 | 0.75 | 0.38 | 0.75 | 0.38 | 0.73 |
Embitterment | 0.56 | 0.70 | 0.59 | 0.68 | 0.58 | 0.68 | 0.59 | 0.65 |
Trait Irritability | 0.51 | 0.70 | 0.55 | 0.70 | 0.55 | 0.70 | 0.52 | 0.66 |
Mistrust | 0.68 | 0.66 | 0.72 | 0.67 | 0.72 | 0.67 | 0.78 | 0.64 |
Verbal Trait Aggression | 0.46 | 0.58 | 0.53 | 0.64 | 0.52 | 0.64 | 0.53 | 0.59 |
Physical Trait Aggression | 0.52 | 0.69 | 0.54 | 0.75 | 0.54 | 0.75 | 0.54 | 0.68 |
Between-subject analyses
For the analysis of mean differences between psychotic patients and non-psychotic individuals MANCOVA between-subjects analysis was significant with regard to diagnosis (Wilk’s lambda 0.563, p < 0.001) and gender (Wilk’s lambda 0.682, p < 0.001) but not to age (Wilk’s lambda 0.908, p = 0.715) or interaction between diagnosis and gender (Wilk’s lambda 0.873, p = 0.402). In post-hoc analyses ANCOVAs were performed for each of the SSP scales. For seven of the scales, i.e. Somatic trait anxiety (F = 26.0, p < 0.001), Psychic trait anxiety (F = 43.9, p < 0.001), Stress Susceptibility (F = 28.7, p < 0.001), Lack of Assertiveness (F = 20.6, p < 0.001), Detachment (F = 14.6, p < 0.001), Embitterment (F = 45.5, p < 0.001), and Mistrust (F = 25.0, p < 0.001) patients scored significantly higher than controls, whereas for six (Impulsiveness [F = 0.8, p = 0.371], Adventure seeking [F = 0.2, p = 0.650]; Social desirability [F = 0.9, p = 0.345], Trait Irritability [F = 0.2, p = 0.621], Verbal Trait Aggression [F = 1.3, p = 0.27], Physical Trait Aggression [F = 0.3, p = 0.609]) no significant differences were found. Age effects were found for Psychic Trait Anxiety (F = 3.8, p = 0.049), gender effects were found for Impulsiveness (F = 4.8, p = 0.031) and Detachment (F = 11.7, p = 0.001) and interaction diagnosis * gender effect was found for Somatic Trait Anxiety (F = 3.9, p = 0.050).
Power
The statistical power was computed using the G*Power (version 3) freeware Power calculator [
48]. Given α = 0.05 and a mean difference of z = 0.5, the sample of patients (
n = 36) had a power of 83% whereas the sample of non-psychotic individuals (
n = 76) had a power of 99%.
Discussion
The main finding of the present study is that SSP mean scale scores did not vary significantly during the five-year interval. Within-subjects correlations showed less stability for the rank order between individuals for some of the scales, especially among patients. The stability of the SSP personality traits was reasonably high among patients with psychotic disorder, although lower than among non-psychotic individuals. This is in accordance with previous studies using the Five-Factor Model and MMPI [
13‐
16].
We know about three previous studies in which the same individuals have been investigated with the SSP inventory at two different time-points [
25‐
27]. With regard to stability over time these three studies give overall similar results as the present study, despite different time span (two – three months versus five years), different ages and different patient categories investigated. The z-score deviation between baseline and follow-up in the present study never exceeded 0.5, which is considered as a lower limit for a non-trivial difference [
45,
46]. With the exception of Somatic Trait Anxiety in the ICBT-intervention group in the study of health anxiety [
25] and Somatic Trait Anxiety and Psychic Trait Anxiety among the escitalopram-treated Estonian patients with panic disorder [
26] this was not the case in the other studies. The most deviant z-scores in the present study was among controls who scored lower on Psychic Trait Anxiety (− 0.40), Verbal Trait Aggression (− 0.41) and Physical Trait Aggression (− 0.47) at the five-year follow-up than at baseline
, whereas among patients the most deviant measures was that of Trait Irritability (− 0.39). This indicates that the mean SSP trait scores evaluated at different time-points do not differ substantially and that SSP scale scores in general are stable over time periods up to five years.
In the present study there were differences between psychotic patients and non-psychotic individuals with regard to the stability of interpersonal correlations for two SSP scales: Detachment and Social Desirability. In an attempt to explain these differences we analysed the impact of verbal IQ (WAIS verbal IQ) and functioning (GAF) by correlation with the five-year interpersonal correlations of Detachment and Social Desirability. We also analyzed if psychotic negative (SANS) or positive symptoms (SAPS) were associated with Detachment and Social Desirability interpersonal correlations among patients. However, we did not find any significant association for either of these analyses (data not shown). Thus, we were not able to find the reason why the stability differed between patients and controls for these two SSP scales. The sample was small, and therefore we may have had too little power to detect a difference. It is also possible that these differences may have occurred by chance or that the differences were due to other factors not accounted for in our study. Interestingly, Kentros and co-workers [
13] found a lower stability with regard to NEO Agreeableness in patients with psychosis. SSP Social Desirability has been shown to be associated with NEO Agreeableness [
21], indicating some concordance between the study of Kentros and co-workers and the present study.
Kentros and collaborators [
13] reported overall stability of personality traits, despite substantial variation with regard to psychotic symptoms. Beauchamp et al. [
14] found both results in favour of and in disagreement with the idea that personality is associated with psychotic symptoms over a three-month period, whereas Boyette and co-workers [
15] reported lower three-year correlations among psychotic patients than controls with regard to NEO Neuroticism, which was associated with depressive symptoms. Thus, stability with regard to the Five-Factor Model among psychotic patients seems to be overall steady, with a few exceptions, similar to the results of the present study using SSP. In contrast, among the MMPI personality traits analysed by Horan and collaborators over a 15-month period the majority was influenced by psychiatric symptoms [
16]. In this context, the attempts to overcome shortcomings in traditional psychopathological taxonomy by incorporating personality variation, partly overlapping with aspects of psychopathology is of interest [
50].
Case-control differences
In this study patients scored higher than controls in six neuroticism-related SSP-scales, i.e. Somatic Trait Anxiety, Psychic Trait Anxiety, Stress Susceptibility, Lack of Assertiveness, Embitterment and Mistrust, as well as Detachment, a negative facet of extraversion. This is consistent with a previous study [
22], from which the majority of the present research individuals constitute a sub-sample. Given this fact and the relative stability of the personality traits over time this is anticipated. The results are also in agreement with the majority of previous studies using other personality instruments that indicate that facets of neuroticism are particularly prominent in patients with psychotic disorders [
3,
8,
10,
11,
23,
24].
Strength and limitations
One limitation of the current study is that the participants had agreed to take part in an extensive biological research. This makes neither the group with patients nor the healthy subjects fully representative. The presence of a non-psychotic control group, involved in the same demanding research as the patients, is on the other hand a strength of the study. Another limitation is the high attrition rate, making the number of participants included in the study limited, which may have reduced our possibility to find age-related personality changes. High drop-out rates is unfortunately common in follow-up studies performed several years apart. This may have given our sample more subjects with non-significant tendencies to getting worse over time, making the conclusions less valid for subjects without such tendencies. Another limitation was the relatively small number of women, giving rise to a gender disparity in the group of patients relative to the overall reported gender distribution of psychotic disorders in the population [
51]. Participants in the present study were adults in the middle age (mean age at baseline about 40 years), a part of life known to be relatively stable with regard to most personality traits in the general population [
12]. Also the previous studies [
13‐
16] analyzing personality over time in patients with psychosis studied adult patients but at lower ages (mean ages at baseline from 23 to 34 years), although after the adolescence period. The age ranges may thus have diminished the possibility to detect differences in all these studies. The patients were not investigated with any instrument assessing personality disorder. Non-psychotic individuals were however given the SCID-II screen questionnaire [
52] at baseline but there was none fulfilling suggested criteria for any personality disorder. The lack of assessment of personality disorder diagnoses adds to the limitations of the study. The SSP, used in the present study, is not identical with the personality inventories used in previous studies. This complicates the ability to compare the current study with previous studies. However, SSP captures several of the personality aspects that are measured by other questionnaires and may have special advantages as the relatively small numbers of items comparing to other personality constructs and the use of a simple and timeless language. Some scales in SSP and its predecessors also appear to have biological relevance [
53‐
55].