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Erschienen in: Surgical Endoscopy 1/2017

10.06.2016

Standard laparoscopic versus robotic retromuscular ventral hernia repair

verfasst von: Jeremy A. Warren, William S. Cobb, Joseph A. Ewing, Alfredo M. Carbonell

Erschienen in: Surgical Endoscopy | Ausgabe 1/2017

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Abstract

Background

Laparoscopic ventral hernia repair (LVHR) demonstrates comparable recurrence rates, but lower incidence of surgical site infection (SSI) than open repair. Delayed complications can occur with intraperitoneal mesh, particularly if a subsequent abdominal operation is required, potentially resulting in bowel injury. Robotic retromuscular ventral hernia repair (RRVHR) allows abdominal wall reconstruction (AWR) and extraperitoneal mesh placement previously only possible with open repair, with the wound morbidity of LVHR.

Methods

All LVHR and RRVHR performed in our institution between June 2013 and May 2015 contained in the Americas Hernia Society Quality Collaborative database were analyzed. Continuous bivariate analysis was performed with Student’s t test. Continuous nonparametric data were compared with Chi-squared test, or Fisher’s exact for small sample sizes. p values <0.05 were considered significant.

Results

We compared 103 LVHR with 53 RRVHR. LVHR patients were older (60.2 vs. 52.9 years; p = 0.001), but demographics were otherwise similar between groups. Hernia width was similar (6.9 vs. 6.5 cm, p = 0.508). Fascial closure was achieved more often with RRVHR (96.2 vs. 50.5 %; p < 0.001) and aided by myofascial release in 43.4 %. Mesh was placed in an intraperitoneal position in 90.3 % of LVHR and extraperitoneal in 96.2 % of RRVHR. RRVHR operative time was longer (245 vs. 122 min, p < 0.001). Narcotic requirement was similar between LVHR and RRVHR (1.8 vs. 1.4 morphine equivalents/h; p = 0.176). Seroma was more common after RRVHR (47.2 vs. 16.5 %, p < 0.001), but SSI was similar (3.8 vs. 1 %, p = 0.592). Median length of stay was shorter after RRVHR (1 vs. 2 days, p = 0.004). Direct hospital cost was similar (LVHR $13,943 vs. RRVHR $19,532; p = 0.07).

Conclusion

RRVHR enables true AWR, with myofascial release to offset tension for midline fascial closure, and obviates the need for intraperitoneal mesh. Perioperative morbidity of RRVHR is comparable to LVHR, with shorter length of stay despite a longer operative time and extensive tissue dissection.
Literatur
1.
Zurück zum Zitat LeBlanc KA, Booth WV (1993) Laparoscopic repair of incisional abdominal hernias using expanded polytetrafluoroethylene: preliminary findings. Surg Laparosc Endosc 3:39–41PubMed LeBlanc KA, Booth WV (1993) Laparoscopic repair of incisional abdominal hernias using expanded polytetrafluoroethylene: preliminary findings. Surg Laparosc Endosc 3:39–41PubMed
2.
Zurück zum Zitat Vorst AL, Kaoutzanis C, Carbonell AM, Franz MG (2015) Evolution and advances in laparoscopic ventral and incisional hernia repair. World J Gastrointest Surg 7:293–305CrossRefPubMedPubMedCentral Vorst AL, Kaoutzanis C, Carbonell AM, Franz MG (2015) Evolution and advances in laparoscopic ventral and incisional hernia repair. World J Gastrointest Surg 7:293–305CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Tsui C, Klein R, Garabrant M (2013) Minimally invasive surgery: national trends in adoption and future directions for hospital strategy. Surg Endosc 27:2253–2257CrossRefPubMed Tsui C, Klein R, Garabrant M (2013) Minimally invasive surgery: national trends in adoption and future directions for hospital strategy. Surg Endosc 27:2253–2257CrossRefPubMed
4.
Zurück zum Zitat Ramshaw BJ, Esartia P, Schwab J (1999) Comparison of laparoscopic and open ventral herniorrhapy. Am Surg 65:827–832PubMed Ramshaw BJ, Esartia P, Schwab J (1999) Comparison of laparoscopic and open ventral herniorrhapy. Am Surg 65:827–832PubMed
5.
Zurück zum Zitat Pierce RA, Spitler JA, Frisella MM, Matthews BD, Brunt LM (2007) Pooled data analysis of laparoscopic vs. open ventral hernia repair: 14 years of patient data accrual. Surg Endosc 21:378–386CrossRefPubMed Pierce RA, Spitler JA, Frisella MM, Matthews BD, Brunt LM (2007) Pooled data analysis of laparoscopic vs. open ventral hernia repair: 14 years of patient data accrual. Surg Endosc 21:378–386CrossRefPubMed
6.
Zurück zum Zitat Halabi WJ, Jafari MD, Carmichael JC, Nguyen VQ, Mills S, Phelan M, Stamos MJ, Pigazzi A (2013) Laparoscopic versus open repair of parastomal hernias: an ACS-NSQIP analysis of short-term outcomes. Surg Endosc 27:4067–4072CrossRefPubMed Halabi WJ, Jafari MD, Carmichael JC, Nguyen VQ, Mills S, Phelan M, Stamos MJ, Pigazzi A (2013) Laparoscopic versus open repair of parastomal hernias: an ACS-NSQIP analysis of short-term outcomes. Surg Endosc 27:4067–4072CrossRefPubMed
7.
Zurück zum Zitat Itani KMF, Hur K, Kim LT, Anthony T, Berger DH, Reda D, Neumayer L, Veterans Affairs Ventral Incisional Hernia Investigators (2010) Comparison of laparoscopic and open repair with mesh for the treatment of ventral incisional hernia: a randomized trial. Arch Surg 145:322–328CrossRefPubMed Itani KMF, Hur K, Kim LT, Anthony T, Berger DH, Reda D, Neumayer L, Veterans Affairs Ventral Incisional Hernia Investigators (2010) Comparison of laparoscopic and open repair with mesh for the treatment of ventral incisional hernia: a randomized trial. Arch Surg 145:322–328CrossRefPubMed
8.
Zurück zum Zitat Muysoms F, Vander Mijnsbrugge G, Pletinckx P, Boldo E, Jacobs I, Michiels M, Ceulemans R (2013) Randomized clinical trial of mesh fixation with “double crown” versus “sutures and tackers” in laparoscopic ventral hernia repair. Hernia 17:603–612CrossRefPubMed Muysoms F, Vander Mijnsbrugge G, Pletinckx P, Boldo E, Jacobs I, Michiels M, Ceulemans R (2013) Randomized clinical trial of mesh fixation with “double crown” versus “sutures and tackers” in laparoscopic ventral hernia repair. Hernia 17:603–612CrossRefPubMed
9.
Zurück zum Zitat Colavita PD, Tsirline VB, Belyansky I, Walters AL, Lincourt AE, Sing RF, Heniford BT (2012) Prospective, long-term comparison of quality of life in laparoscopic versus open ventral hernia repair. Ann Surg 256:714–722CrossRefPubMed Colavita PD, Tsirline VB, Belyansky I, Walters AL, Lincourt AE, Sing RF, Heniford BT (2012) Prospective, long-term comparison of quality of life in laparoscopic versus open ventral hernia repair. Ann Surg 256:714–722CrossRefPubMed
10.
Zurück zum Zitat Liang MK, Clapp M, Li LT, Berger RL, Hicks SC (2013) Patient satisfaction, chronic pain, and functional status following laparoscopic ventral hernia repair. World J Surg 37:530–537CrossRefPubMed Liang MK, Clapp M, Li LT, Berger RL, Hicks SC (2013) Patient satisfaction, chronic pain, and functional status following laparoscopic ventral hernia repair. World J Surg 37:530–537CrossRefPubMed
11.
Zurück zum Zitat Halm JA, De Wall LL, Steyerberg EW, Jeekel J, Lange JF (2007) Intraperitoneal polypropylene mesh hernia repair complicates subsequent abdominal surgery. World J Surg 31:423–429CrossRefPubMed Halm JA, De Wall LL, Steyerberg EW, Jeekel J, Lange JF (2007) Intraperitoneal polypropylene mesh hernia repair complicates subsequent abdominal surgery. World J Surg 31:423–429CrossRefPubMed
12.
Zurück zum Zitat Gray SH, Vick CC, Graham LA, Finan KR, Neumayer LA, Hawn MT (2008) Risk of complications from enterotomy or unplanned bowel resection during elective hernia repair. Arch Surg 143:582–586CrossRefPubMed Gray SH, Vick CC, Graham LA, Finan KR, Neumayer LA, Hawn MT (2008) Risk of complications from enterotomy or unplanned bowel resection during elective hernia repair. Arch Surg 143:582–586CrossRefPubMed
13.
Zurück zum Zitat Shaver M, Cobb WS, Carbonell AM (2016) A 10-year experience with periprosthetic mesh infections. Hernia Supp 1:S66 Shaver M, Cobb WS, Carbonell AM (2016) A 10-year experience with periprosthetic mesh infections. Hernia Supp 1:S66
14.
Zurück zum Zitat Carter SA, Hicks SC, Brahmbhatt R, Liang MK (2014) Recurrence and pseudorecurrence after laparoscopic ventral hernia repair: predictors and patient-focused outcomes. Am Surg 80:138–148PubMed Carter SA, Hicks SC, Brahmbhatt R, Liang MK (2014) Recurrence and pseudorecurrence after laparoscopic ventral hernia repair: predictors and patient-focused outcomes. Am Surg 80:138–148PubMed
15.
Zurück zum Zitat Kurmann A, Visth E, Candinas D, Beldi G (2011) Long-term follow-up of open and laparoscopic repair of large incisional hernias. World J Surg 35:297–301CrossRefPubMed Kurmann A, Visth E, Candinas D, Beldi G (2011) Long-term follow-up of open and laparoscopic repair of large incisional hernias. World J Surg 35:297–301CrossRefPubMed
16.
Zurück zum Zitat Burger JWA, Luijendijk RW, Hop WCJ, Halm JA, Verdaasdonk EGG, Jeekel J (2004) Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia. Ann Surg 240:578–583PubMedPubMedCentral Burger JWA, Luijendijk RW, Hop WCJ, Halm JA, Verdaasdonk EGG, Jeekel J (2004) Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia. Ann Surg 240:578–583PubMedPubMedCentral
17.
Zurück zum Zitat Booth JH, Garvey PB, Baumann DP, Selber JC, Nguyen AT, Clemens MW, Liu J, Butler CE (2013) Primary fascial closure with mesh reinforcement is superior to bridged mesh repair for abdominal wall reconstruction. J Am Coll Surg 217:999–1009CrossRefPubMed Booth JH, Garvey PB, Baumann DP, Selber JC, Nguyen AT, Clemens MW, Liu J, Butler CE (2013) Primary fascial closure with mesh reinforcement is superior to bridged mesh repair for abdominal wall reconstruction. J Am Coll Surg 217:999–1009CrossRefPubMed
18.
Zurück zum Zitat Itani KMF, Rosen M, Vargo D, Awad SS, Denoto G, Butler CE, RICH Study Group (2012) Prospective study of single-stage repair of contaminated hernias using a biologic porcine tissue matrix: the RICH study. Surgery 152:498–505CrossRef Itani KMF, Rosen M, Vargo D, Awad SS, Denoto G, Butler CE, RICH Study Group (2012) Prospective study of single-stage repair of contaminated hernias using a biologic porcine tissue matrix: the RICH study. Surgery 152:498–505CrossRef
19.
Zurück zum Zitat Rives J, Pire JC, Flament JB, Convers G (1977) Treatment of large eventrations (apropos of 133 cases). Minerva Chir 32:749–756PubMed Rives J, Pire JC, Flament JB, Convers G (1977) Treatment of large eventrations (apropos of 133 cases). Minerva Chir 32:749–756PubMed
20.
Zurück zum Zitat Jin J, Rosen MJ (2008) Laparoscopic versus open ventral hernia repair. Surg Clin N Am 88:1083–1100CrossRefPubMed Jin J, Rosen MJ (2008) Laparoscopic versus open ventral hernia repair. Surg Clin N Am 88:1083–1100CrossRefPubMed
21.
Zurück zum Zitat Albino FP, Patel KM, Nahabedian MY, Sosin M, Attinger CE, Bhanot P (2013) Does mesh location matter in abdominal wall reconstruction? a systematic review of the literature and a summary of recommendations. Plast Reconstr Surg 132:1295–1304CrossRefPubMed Albino FP, Patel KM, Nahabedian MY, Sosin M, Attinger CE, Bhanot P (2013) Does mesh location matter in abdominal wall reconstruction? a systematic review of the literature and a summary of recommendations. Plast Reconstr Surg 132:1295–1304CrossRefPubMed
22.
Zurück zum Zitat Israelsson LA, Smedberg S, Montgomery A, Nordin P (2006) Incisional hernia repair in Sweden 2002. Hernia 10:258–261CrossRefPubMed Israelsson LA, Smedberg S, Montgomery A, Nordin P (2006) Incisional hernia repair in Sweden 2002. Hernia 10:258–261CrossRefPubMed
23.
Zurück zum Zitat Rodríguez-Sanjuán JC, Gómez-Ruiz M, Trugeda-Carrera S, Manuel-Palazuelos C, López-Useros A, Gómez-Fleitas M (2016) Laparoscopic and robot-assisted laparoscopic digestive surgery: present and future directions. World J Gastronterol 22:1975–2004CrossRef Rodríguez-Sanjuán JC, Gómez-Ruiz M, Trugeda-Carrera S, Manuel-Palazuelos C, López-Useros A, Gómez-Fleitas M (2016) Laparoscopic and robot-assisted laparoscopic digestive surgery: present and future directions. World J Gastronterol 22:1975–2004CrossRef
24.
Zurück zum Zitat Altieri MS, Yang J, Telem DA, Zhu J, Halbert C, Talamini M, Pryor AD (2016) Robotic approaches may offer benefit in colorectal procedures, more controversial in other areas: a review of 168,248 cases. Surg Endosc 30:925–933CrossRefPubMed Altieri MS, Yang J, Telem DA, Zhu J, Halbert C, Talamini M, Pryor AD (2016) Robotic approaches may offer benefit in colorectal procedures, more controversial in other areas: a review of 168,248 cases. Surg Endosc 30:925–933CrossRefPubMed
25.
Zurück zum Zitat Abdalla RZ, Garcia RB, Costa R, Luca C (2012) Procedimento de Rives/Stoppa modificado robô-assistido para correção de hérnias ventrais da linha média. ABCD Arq Bras Cir Dig 25:129–132CrossRefPubMed Abdalla RZ, Garcia RB, Costa R, Luca C (2012) Procedimento de Rives/Stoppa modificado robô-assistido para correção de hérnias ventrais da linha média. ABCD Arq Bras Cir Dig 25:129–132CrossRefPubMed
26.
Zurück zum Zitat Warren J, Cobb W, Ewing J, Carbonell A (2015) Prospective observational cohort study of robotic vs open Rives-Stoppa retrorectus incisional hernia repair. Hernia 19:S177–S186CrossRefPubMed Warren J, Cobb W, Ewing J, Carbonell A (2015) Prospective observational cohort study of robotic vs open Rives-Stoppa retrorectus incisional hernia repair. Hernia 19:S177–S186CrossRefPubMed
27.
Zurück zum Zitat Banerjee A, Beck C, Narula VK, Linn J, Noria S, Zagol B, Mikami DJ (2012) Laparoscopic ventral hernia repair: does primary repair in addition to placement of mesh decrease recurrence? Surg Endosc 26:1264–1268CrossRefPubMed Banerjee A, Beck C, Narula VK, Linn J, Noria S, Zagol B, Mikami DJ (2012) Laparoscopic ventral hernia repair: does primary repair in addition to placement of mesh decrease recurrence? Surg Endosc 26:1264–1268CrossRefPubMed
28.
Zurück zum Zitat Allison N, Tieu K, Snyder B, Pigazzi A, Wilson E (2012) Technical feasibility of robot-assisted ventral hernia repair. World J Surg 36:447–452CrossRefPubMed Allison N, Tieu K, Snyder B, Pigazzi A, Wilson E (2012) Technical feasibility of robot-assisted ventral hernia repair. World J Surg 36:447–452CrossRefPubMed
29.
Zurück zum Zitat Gonzalez AM, Romero RJ, Seetharamaiah R, Gallas M, Lamoureux J, Rabaza JR (2015) Laparoscopic ventral hernia repair with primary closure versus no primary closure of the defect: potential benefits of the robotic technology. Int J Med Robot 11:120–125CrossRefPubMed Gonzalez AM, Romero RJ, Seetharamaiah R, Gallas M, Lamoureux J, Rabaza JR (2015) Laparoscopic ventral hernia repair with primary closure versus no primary closure of the defect: potential benefits of the robotic technology. Int J Med Robot 11:120–125CrossRefPubMed
30.
Zurück zum Zitat Dragu A, Klein P, Unglaub F, Polykandriotis E, Kneser U, Hohenberger W, Horch RE (2009) Tensiometry as a decision tool for abdominal wall reconstruction with component separation. World J Surg 33:1174–1180CrossRefPubMed Dragu A, Klein P, Unglaub F, Polykandriotis E, Kneser U, Hohenberger W, Horch RE (2009) Tensiometry as a decision tool for abdominal wall reconstruction with component separation. World J Surg 33:1174–1180CrossRefPubMed
31.
Zurück zum Zitat Orenstein SB, Dumeer JL, Monteagudo J, Poi MJ, Novitsky YW (2011) Outcomes of laparoscopic ventral hernia repair with routine defect closure using “shoelacing” technique. Surg Endosc 25:1452–1457CrossRefPubMed Orenstein SB, Dumeer JL, Monteagudo J, Poi MJ, Novitsky YW (2011) Outcomes of laparoscopic ventral hernia repair with routine defect closure using “shoelacing” technique. Surg Endosc 25:1452–1457CrossRefPubMed
32.
Zurück zum Zitat Harth KC, Rosen MJ (2010) Endoscopic versus open component separation in complex abdominal wall reconstruction. Am J Surg 199:342–346CrossRefPubMed Harth KC, Rosen MJ (2010) Endoscopic versus open component separation in complex abdominal wall reconstruction. Am J Surg 199:342–346CrossRefPubMed
33.
Zurück zum Zitat Novitsky YW, Elliott HL, Orenstein SB, Rosen MJ (2012) Transversus abdominis muscle release: a novel approach to posterior component separation during complex abdominal wall reconstruction. Am J Surg 204:709–716CrossRefPubMed Novitsky YW, Elliott HL, Orenstein SB, Rosen MJ (2012) Transversus abdominis muscle release: a novel approach to posterior component separation during complex abdominal wall reconstruction. Am J Surg 204:709–716CrossRefPubMed
34.
Zurück zum Zitat Willard FH, Vleeming A, Schuenke MD, Danneels L, Schleip R (2012) The thoracolumbar fascia: anatomy, function and clinical considerations. J Anat 221:507–536CrossRefPubMedPubMedCentral Willard FH, Vleeming A, Schuenke MD, Danneels L, Schleip R (2012) The thoracolumbar fascia: anatomy, function and clinical considerations. J Anat 221:507–536CrossRefPubMedPubMedCentral
35.
Zurück zum Zitat De Silva GS, Krpata DM, Hicks CW, Criss CN, Gao Y, Rosen MJ, Novitsky YW (2014) Comparative radiographic analysis of changes in the abdominal wall musculature morphology after open posterior component separation or bridging laparoscopic ventral hernia repair. J Am Coll Surg 218:353–357CrossRefPubMed De Silva GS, Krpata DM, Hicks CW, Criss CN, Gao Y, Rosen MJ, Novitsky YW (2014) Comparative radiographic analysis of changes in the abdominal wall musculature morphology after open posterior component separation or bridging laparoscopic ventral hernia repair.  J Am Coll Surg 218:353–357CrossRefPubMed
36.
Zurück zum Zitat Snyder CW, Graham LA, Gray SH, Vick CC (2011) Effect of mesh type and position on subsequent abdominal operations after incisional hernia repair. J Am Coll Surg 212:496–504CrossRefPubMed Snyder CW, Graham LA, Gray SH, Vick CC (2011) Effect of mesh type and position on subsequent abdominal operations after incisional hernia repair. J Am Coll Surg 212:496–504CrossRefPubMed
37.
Zurück zum Zitat Liang MK, Li LT, Nguyen MT, Berger RL, Hicks SC, Kao LS (2014) Abdominal reoperation and mesh explantation following open ventral hernia repair with mesh. Am J Surg 208:670–676CrossRefPubMed Liang MK, Li LT, Nguyen MT, Berger RL, Hicks SC, Kao LS (2014) Abdominal reoperation and mesh explantation following open ventral hernia repair with mesh. Am J Surg 208:670–676CrossRefPubMed
38.
Zurück zum Zitat Jenkins ED, Yom V, Melman L, Brunt LM, Eagon JC, Frisella MM, Matthews BD (2010) Prospective evaluation of adhesion characteristics to intraperitoneal mesh and adhesiolysis-related complications during laparoscopic re-exploration after prior ventral hernia repair. Surg Endosc 24:3002–3007CrossRefPubMed Jenkins ED, Yom V, Melman L, Brunt LM, Eagon JC, Frisella MM, Matthews BD (2010) Prospective evaluation of adhesion characteristics to intraperitoneal mesh and adhesiolysis-related complications during laparoscopic re-exploration after prior ventral hernia repair. Surg Endosc 24:3002–3007CrossRefPubMed
39.
Zurück zum Zitat Cobb WS, Warren JA, Ewing JA, Burnikel A, Merchant M, Carbonell AM (2015) Open retromuscular mesh repair of complex incisional hernia: predictors of wound events and recurrence. J Am Coll Surg 220:606–613CrossRefPubMed Cobb WS, Warren JA, Ewing JA, Burnikel A, Merchant M, Carbonell AM (2015) Open retromuscular mesh repair of complex incisional hernia: predictors of wound events and recurrence. J Am Coll Surg 220:606–613CrossRefPubMed
Metadaten
Titel
Standard laparoscopic versus robotic retromuscular ventral hernia repair
verfasst von
Jeremy A. Warren
William S. Cobb
Joseph A. Ewing
Alfredo M. Carbonell
Publikationsdatum
10.06.2016
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 1/2017
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-016-4975-x

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