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05.04.2022 | Status epilepticus | Übersichten

Das ist neu in der Neurointensiv- und Notfallmedizin: die wichtigsten Studien des Jahres im Rück- und Überblick

verfasst von: Angelika Alonso, Prof. Dr. Rainer Kollmar, Konstantin Dimitriadis

Erschienen in: Der Nervenarzt

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Zusammenfassung

Die vorliegende Übersichtsarbeit fasst wichtige klinische Studien der neurologischen Notfall- und Intensivmedizin zwischen 2020 und 2021 zusammen zu den Themen: rekanalisierende Therapie beim ischämischen Schlaganfall, Anwendbarkeit und Auswirkung eines zerebralen Sauerstoffgewebemonitorings bei Subarachnoidalblutung, Wirksamkeit induzierter Hypothermie bei Patienten mit „cardiac arrest“ (CA), Wertigkeit früher kranialer Bildgebung nach CA, Relevanz eines schnellen Managements und medikamentöser Therapie beim Status epilepticus sowie Inzidenz von Critical-illness-Polyneuropathie-Myopathie bei intensivpflichtigen COVID-Patienten.
Literatur
1.
Zurück zum Zitat Beekman R, Maciel CB, Ormseth CH et al (2021) Early head CT in post-cardiac arrest patients: A helpful tool or contributor to self-fulfilling prophecy? Resuscitation 165:68–76 CrossRef Beekman R, Maciel CB, Ormseth CH et al (2021) Early head CT in post-cardiac arrest patients: A helpful tool or contributor to self-fulfilling prophecy? Resuscitation 165:68–76 CrossRef
2.
Zurück zum Zitat Caraganis A, Mulder M, Kempainen RR et al (2020) Interobserver Variability in the Recognition of Hypoxic-Ischemic Brain Injury on Computed Tomography Soon After Out-of-Hospital Cardiac Arrest. Neurocrit Care 33:414–421 CrossRef Caraganis A, Mulder M, Kempainen RR et al (2020) Interobserver Variability in the Recognition of Hypoxic-Ischemic Brain Injury on Computed Tomography Soon After Out-of-Hospital Cardiac Arrest. Neurocrit Care 33:414–421 CrossRef
3.
Zurück zum Zitat Chowdhury SZ, Baskar PS, Bhaskar S (2021) Effect of prehospital workflow optimization on treatment delays and clinical outcomes in acute ischemic stroke: A systematic review and meta-analysis. Acad Emerg Med 2021(28):781–801 CrossRef Chowdhury SZ, Baskar PS, Bhaskar S (2021) Effect of prehospital workflow optimization on treatment delays and clinical outcomes in acute ischemic stroke: A systematic review and meta-analysis. Acad Emerg Med 2021(28):781–801 CrossRef
4.
Zurück zum Zitat Dankiewicz J, Cronberg T, Lilja G et al (2021) TTM2 trial investigators. Hypothermia versus normothermia after out-of-hospital cardiac arrest. N Engl J Med 384:2283–2294 CrossRef Dankiewicz J, Cronberg T, Lilja G et al (2021) TTM2 trial investigators. Hypothermia versus normothermia after out-of-hospital cardiac arrest. N Engl J Med 384:2283–2294 CrossRef
5.
Zurück zum Zitat Duvekot MH, Venema E, Lingsma HF et al (2021) MR CLEAN Registry investigators. Sensitivity of prehospital stroke scales for different intracranial large vessel occlusion locations. Eur Stroke J 6:194–204 CrossRef Duvekot MH, Venema E, Lingsma HF et al (2021) MR CLEAN Registry investigators. Sensitivity of prehospital stroke scales for different intracranial large vessel occlusion locations. Eur Stroke J 6:194–204 CrossRef
6.
Zurück zum Zitat Duvekot MHC, Venema E, Rozeman AD et al (2021) Comparison of eight prehospital stroke scales to detect intracranial large-vessel occlusion in suspected stroke (PRESTO): a prospective observational study. Lancet Neurol 20:213–221 CrossRef Duvekot MHC, Venema E, Rozeman AD et al (2021) Comparison of eight prehospital stroke scales to detect intracranial large-vessel occlusion in suspected stroke (PRESTO): a prospective observational study. Lancet Neurol 20:213–221 CrossRef
7.
Zurück zum Zitat Feng Y, Chen Y, Jia Y et al (2021) Efficacy and safety of levetiracetam versus (fos)phenytoin for second-line treatment of epilepticus: a meta-analysis of latest randomized controlled trials. Seizure 91:339–345 CrossRef Feng Y, Chen Y, Jia Y et al (2021) Efficacy and safety of levetiracetam versus (fos)phenytoin for second-line treatment of epilepticus: a meta-analysis of latest randomized controlled trials. Seizure 91:339–345 CrossRef
8.
Zurück zum Zitat Frithiof R, Rostami E, Kumlien E, Virhammar J, Fällmar D, Hultström M, Lipcsey M, Ashton N, Blennow K, Zetterberg H, Punga AR (2021) Critical illness polyneuropathy, myopathy and neuronal biomarkers in COVID-19 patients: a prospective study. Clin Neurophysiol 132:1733–1740 CrossRef Frithiof R, Rostami E, Kumlien E, Virhammar J, Fällmar D, Hultström M, Lipcsey M, Ashton N, Blennow K, Zetterberg H, Punga AR (2021) Critical illness polyneuropathy, myopathy and neuronal biomarkers in COVID-19 patients: a prospective study. Clin Neurophysiol 132:1733–1740 CrossRef
9.
Zurück zum Zitat Gouvea Bogossian E, Diaferia D, Ndieugnou Djangang N et al (2021) Brain tissue oxygenation guided therapy and outcome in non-traumatic subarachnoid hemorrhage. Sci Rep 11:16235 CrossRef Gouvea Bogossian E, Diaferia D, Ndieugnou Djangang N et al (2021) Brain tissue oxygenation guided therapy and outcome in non-traumatic subarachnoid hemorrhage. Sci Rep 11:16235 CrossRef
10.
Zurück zum Zitat Guterman EL, Sanford JK, Betjemann JP et al (2020) Prehospital midazolam use and outcomes among patients with out-of-hospital status epilepticus. Neurology 95:e3203–e3212 CrossRef Guterman EL, Sanford JK, Betjemann JP et al (2020) Prehospital midazolam use and outcomes among patients with out-of-hospital status epilepticus. Neurology 95:e3203–e3212 CrossRef
11.
Zurück zum Zitat Gutiérrez-Viedma Á, Parejo-Carbonell B, Romeral-Jiménez M et al (2021) Therapy delay in status epilepticus extends its duration and worsens its prognosis. Acta Neurol Scand 143:281–289 CrossRef Gutiérrez-Viedma Á, Parejo-Carbonell B, Romeral-Jiménez M et al (2021) Therapy delay in status epilepticus extends its duration and worsens its prognosis. Acta Neurol Scand 143:281–289 CrossRef
12.
Zurück zum Zitat Haller JT, Bonnin S, Radosevich J (2021) Rapid administration of undiluted intravenous levetiracetam. Epilepsia 62:1865–1870 CrossRef Haller JT, Bonnin S, Radosevich J (2021) Rapid administration of undiluted intravenous levetiracetam. Epilepsia 62:1865–1870 CrossRef
15.
Zurück zum Zitat Kaesmacher J, Meinel TR, Nannoni S et al (2021) Bridging May increase the risk of symptomatic Intracranial hemorrhage in thrombectomy patients with low Alberta stroke program early computed Tomography score. Stroke 52:1098–1104 CrossRef Kaesmacher J, Meinel TR, Nannoni S et al (2021) Bridging May increase the risk of symptomatic Intracranial hemorrhage in thrombectomy patients with low Alberta stroke program early computed Tomography score. Stroke 52:1098–1104 CrossRef
16.
Zurück zum Zitat Kapur J, Elm J, Chamberlain JM et al (2019) Randomized trial of three anticonvulsant medications for status epilepticus. N Engl J Med 381:2103–2113 CrossRef Kapur J, Elm J, Chamberlain JM et al (2019) Randomized trial of three anticonvulsant medications for status epilepticus. N Engl J Med 381:2103–2113 CrossRef
17.
Zurück zum Zitat Langezaal LCM, van der Hoeven EJRJ, Mont’Alverne FJA et al (2021) Endovascular therapy for stroke due to basilar-artery occlusion. N Engl J Med 384:1910–1920 CrossRef Langezaal LCM, van der Hoeven EJRJ, Mont’Alverne FJA et al (2021) Endovascular therapy for stroke due to basilar-artery occlusion. N Engl J Med 384:1910–1920 CrossRef
18.
Zurück zum Zitat LeCouffe NE, Kappelhof M, Treurniet KM et al (2021) A randomized trial of intravenous alteplase before endovascular treatment for stroke. N Engl J Med 385:1833–1844 CrossRef LeCouffe NE, Kappelhof M, Treurniet KM et al (2021) A randomized trial of intravenous alteplase before endovascular treatment for stroke. N Engl J Med 385:1833–1844 CrossRef
19.
Zurück zum Zitat Liu X, Dai Q, Ye R, Zi W, Liu Y, Wang H et al (2020) Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial. Lancet Neurol 19:115–122 CrossRef Liu X, Dai Q, Ye R, Zi W, Liu Y, Wang H et al (2020) Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial. Lancet Neurol 19:115–122 CrossRef
20.
21.
Zurück zum Zitat Nguyen TN, Abdalkader M, Nagel S et al (2022) Noncontrast computed tomography vs computed tomography perfusion or magnetic resonance imaging selection in late presentation of stroke with large-vessel occlusion. JAMA Neurol 79:22–31 CrossRef Nguyen TN, Abdalkader M, Nagel S et al (2022) Noncontrast computed tomography vs computed tomography perfusion or magnetic resonance imaging selection in late presentation of stroke with large-vessel occlusion. JAMA Neurol 79:22–31 CrossRef
22.
Zurück zum Zitat Nolan JP, Sandroni C, Böttiger BW et al (2021) European resuscitation council and European society of intensive care medicine guidelines 2021: post-resuscitation care. Resuscitation 161:220–269 CrossRef Nolan JP, Sandroni C, Böttiger BW et al (2021) European resuscitation council and European society of intensive care medicine guidelines 2021: post-resuscitation care. Resuscitation 161:220–269 CrossRef
23.
Zurück zum Zitat Scarpino M, Bonizzoli M, Lazzeri C et al (2021) Electrodiagnostic findings in patients with non-COVID-19- and COVID-19-related acute respiratory distress syndrome. Acta Neurol Scand 144:161–169 CrossRef Scarpino M, Bonizzoli M, Lazzeri C et al (2021) Electrodiagnostic findings in patients with non-COVID-19- and COVID-19-related acute respiratory distress syndrome. Acta Neurol Scand 144:161–169 CrossRef
24.
Zurück zum Zitat Shahrestani S, Wishart D, Han SMJ et al (2021) A systematic review of next-generation point-of-care stroke diagnostic technologies. Neurosurg Focus 51:E11 CrossRef Shahrestani S, Wishart D, Han SMJ et al (2021) A systematic review of next-generation point-of-care stroke diagnostic technologies. Neurosurg Focus 51:E11 CrossRef
25.
Zurück zum Zitat Streitberger KJ, Endisch C, Ploner CJ et al (2019) Timing of brain computed tomography and accuracy of outcome prediction after cardiac arrest. Resuscitation 145:8–14 CrossRef Streitberger KJ, Endisch C, Ploner CJ et al (2019) Timing of brain computed tomography and accuracy of outcome prediction after cardiac arrest. Resuscitation 145:8–14 CrossRef
26.
Zurück zum Zitat Weant KA, Barré SL, Bruner S et al (2021) Assessment of benzodiazepine dosing strategies for the management of status epilepticus in the emergency department. Am J Emerg Med 44:106–111 CrossRef Weant KA, Barré SL, Bruner S et al (2021) Assessment of benzodiazepine dosing strategies for the management of status epilepticus in the emergency department. Am J Emerg Med 44:106–111 CrossRef
27.
Zurück zum Zitat Yang P, Zhang Y, Zhang L et al (2020) Endovascular thrombectomy with or without intravenous Alteplase in acute stroke. N Engl J Med 382:1981–1993 CrossRef Yang P, Zhang Y, Zhang L et al (2020) Endovascular thrombectomy with or without intravenous Alteplase in acute stroke. N Engl J Med 382:1981–1993 CrossRef
28.
Zurück zum Zitat Zi W, Qiu Z, Li F et al (2021) Effect of endovascular treatment alone vs intravenous alteplase plus endovascular treatment on functional independence in patients with acute Ischemic stroke. JAMA 325:234–243 CrossRef Zi W, Qiu Z, Li F et al (2021) Effect of endovascular treatment alone vs intravenous alteplase plus endovascular treatment on functional independence in patients with acute Ischemic stroke. JAMA 325:234–243 CrossRef
Metadaten
Titel
Das ist neu in der Neurointensiv- und Notfallmedizin: die wichtigsten Studien des Jahres im Rück- und Überblick
verfasst von
Angelika Alonso
Prof. Dr. Rainer Kollmar
Konstantin Dimitriadis
Publikationsdatum
05.04.2022
Verlag
Springer Medizin
Erschienen in
Der Nervenarzt
Print ISSN: 0028-2804
Elektronische ISSN: 1433-0407
DOI
https://doi.org/10.1007/s00115-022-01285-3