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Erschienen in: HNO 10/2017

16.03.2017 | Rhinoconjunctivitis allergica | Leitthema

Stellenwert der nasalen Provokation bei Hausstaubmilbenallergie

verfasst von: PD Dr. med. B. R. Haxel

Erschienen in: HNO | Ausgabe 10/2017

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Zusammenfassung

Hausstaubmilbenallergiker zeigen häufig deutlich unterschiedliche Symptome gegenüber Patienten mit Allergien auf andere Inhalationsallergene. Das Vorkommen eines allergischen Asthmas ist deutlich erhöht. Die Diagnostik kann daher eine Herausforderung sein. Vor allem ist es wichtig, eine klinisch „stumme“ Sensibilisierung von einer manifesten Allergie zu differenzieren. Die nasale Provokationstestung (NPT) ist eine geeignete Methode, Patienten zu selektieren, um sie einer kausalen Therapie (spezifische Immuntherapie) zuzuführen. Positionspapiere zur Methodik und Beurteilung der NPT sind verfügbar. Es zeigt sich zwar eine Korrelation der Provokationsergebnisse mit den gängigen Testverfahren (Pricktest, allergenspezifisches IgE), allerdings ist dies teilweise ungenau. Die Durchführung einer NPT bei Verdacht auf Vorliegen einer Hausstaubmilbenallergie ist bei Patienten mit fragwürdiger Anamnese bzw. unklaren Haut- und Bluttestergebnissen empfehlenswert, insbesondere vor Beginn einer Immuntherapie.
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Metadaten
Titel
Stellenwert der nasalen Provokation bei Hausstaubmilbenallergie
verfasst von
PD Dr. med. B. R. Haxel
Publikationsdatum
16.03.2017
Verlag
Springer Medizin
Erschienen in
HNO / Ausgabe 10/2017
Print ISSN: 0017-6192
Elektronische ISSN: 1433-0458
DOI
https://doi.org/10.1007/s00106-017-0342-z

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