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Erschienen in: Journal of Cardiovascular Translational Research 5/2018

15.10.2018 | Review Paper

Stem Cell Homing: a Potential Therapeutic Strategy Unproven for Treatment of Myocardial Injury

verfasst von: Zhonghao Tao, Shihua Tan, Wen Chen, Xin Chen

Erschienen in: Journal of Cardiovascular Translational Research | Ausgabe 5/2018

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Abstract

Despite advances in the prevention and therapeutic modalities of ischemic heart disease, morbidity and mortality post-infarction heart failure remain big challenges in modern society. Stem cell therapy is emerging as a promising therapeutic strategy. Stem cell homing, the ability of stem cells to find their destination, is receiving more attention. Identification of specific cues and understanding the signaling pathways that direct stem cells to targeted destination will improve stem cell homing efficiency. This review discusses the cellular and molecular mechanism of stem cell homing at length in the light of literature and analyzes the problem and considerations of this approach as a treatment strategy for the treatment of ischemic heart disease clinically.
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Metadaten
Titel
Stem Cell Homing: a Potential Therapeutic Strategy Unproven for Treatment of Myocardial Injury
verfasst von
Zhonghao Tao
Shihua Tan
Wen Chen
Xin Chen
Publikationsdatum
15.10.2018
Verlag
Springer US
Erschienen in
Journal of Cardiovascular Translational Research / Ausgabe 5/2018
Print ISSN: 1937-5387
Elektronische ISSN: 1937-5395
DOI
https://doi.org/10.1007/s12265-018-9823-z

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