Skip to main content
Erschienen in: Supportive Care in Cancer 3/2021

06.07.2020 | Original Article

Strategies for living well with hormone-responsive advanced prostate cancer—a qualitative exploration

verfasst von: Lauren Matheson, Jo Nayoan, Carol Rivas, Jo Brett, Penny Wright, Hugh Butcher, Paul Jordan, Anna Gavin, Adam Glaser, Malcolm Mason, Richard Wagland, Eila Watson

Erschienen in: Supportive Care in Cancer | Ausgabe 3/2021

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Due to recent treatment advances, men are increasingly living longer with advanced prostate cancer (PCa). This study sought to understand men’s experiences of living with and adjusting to advanced hormone-responsive PCa and how this influenced their quality of life (QoL), in order to highlight how support could be optimized.

Methods

Participants were recruited through a UK wide survey—the ‘Life After Prostate Cancer Diagnosis’ study. In-depth telephone interviews were conducted with 24 men (aged 46–77 years) with advanced (stage IV) hormone-responsive PCa diagnosed 18–42 months previously. Thematic analysis was undertaken using a framework approach.

Results

Most participants perceived their QoL to be relatively good, which was influenced by the following factors (enablers to ‘living well’ with PCa): a sense of connectedness to others, engagement in meaningful activities, resources (social, cognitive, financial), ability to manage uncertainty, utilization of adjustment strategies and support, communication and information from health professionals. Barriers to ‘living well’ with PCa were often the converse of these factors. These also included more troublesome PCa-related symptoms and stronger perceptions of loss and restriction.

Conclusions

In our study, men living with advanced hormone-responsive PCa often reported a good QoL. Exploring the influences on QoL in men with advanced PCa indicates how future interventions might improve the QoL of men who are struggling. Further research is required to develop and test interventions that enhance QoL for these men.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
4.
Zurück zum Zitat James ND, de Bono JS, Spears MR, Clarke NW, Mason MD, Dearnaley DP, Ritchie AWS, Amos CL, Gilson C, Jones RJ, Matheson D, Millman R, Attard G, Chowdhury S, Cross WR, Gillessen S, Parker CC, Russell JM, Berthold DR, Brawley C, Adab F, Aung S, Birtle AJ, Bowen J, Brock S, Chakraborti P, Ferguson C, Gale J, Gray E, Hingorani M, Hoskin PJ, Lester JF, Malik ZI, McKinna F, McPhail N, Money-Kyrle J, O’Sullivan J, Parikh O, Protheroe A, Robinson A, Srihari NN, Thomas C, Wagstaff J, Wylie J, Zarkar A, Parmar MKB, Sydes MR (2017) Abiraterone for prostate cancer not previously treated with hormone therapy. NEJM 377(4):338–351. https://doi.org/10.1056/NEJMoa1702900CrossRefPubMed James ND, de Bono JS, Spears MR, Clarke NW, Mason MD, Dearnaley DP, Ritchie AWS, Amos CL, Gilson C, Jones RJ, Matheson D, Millman R, Attard G, Chowdhury S, Cross WR, Gillessen S, Parker CC, Russell JM, Berthold DR, Brawley C, Adab F, Aung S, Birtle AJ, Bowen J, Brock S, Chakraborti P, Ferguson C, Gale J, Gray E, Hingorani M, Hoskin PJ, Lester JF, Malik ZI, McKinna F, McPhail N, Money-Kyrle J, O’Sullivan J, Parikh O, Protheroe A, Robinson A, Srihari NN, Thomas C, Wagstaff J, Wylie J, Zarkar A, Parmar MKB, Sydes MR (2017) Abiraterone for prostate cancer not previously treated with hormone therapy. NEJM 377(4):338–351. https://​doi.​org/​10.​1056/​NEJMoa1702900CrossRefPubMed
5.
Zurück zum Zitat Watson E, Shinkins B, Frith E, Neal D, Hamdy F, Walter F, Weller D, Wilkinson C, Faithfull S, Wolstenholme J, Sooriakumaran P, Kastner C, Campbell C, Neal R, Butcher H, Matthews M, Perera R, Rose P (2016) Symptoms, unmet needs, psychological well-being and health status in survivors of prostate cancer: implications for redesigning follow-up. BJU Int 117(6B):E10–E19. https://doi.org/10.1111/bju.13122CrossRefPubMed Watson E, Shinkins B, Frith E, Neal D, Hamdy F, Walter F, Weller D, Wilkinson C, Faithfull S, Wolstenholme J, Sooriakumaran P, Kastner C, Campbell C, Neal R, Butcher H, Matthews M, Perera R, Rose P (2016) Symptoms, unmet needs, psychological well-being and health status in survivors of prostate cancer: implications for redesigning follow-up. BJU Int 117(6B):E10–E19. https://​doi.​org/​10.​1111/​bju.​13122CrossRefPubMed
9.
12.
Zurück zum Zitat Shen MJ, Nelson CJ, Peters E, Slovin SF, Hall SJ, Hall M, Herrera PC, Leventhal EA, Leventhal H, Diefenbach MA (2015) Decision-making processes among prostate cancer survivors with rising PSA levels: results from a qualitative analysis. Med Decis Mak 35(4):477–486. https://doi.org/10.1177/0272989X14558424CrossRef Shen MJ, Nelson CJ, Peters E, Slovin SF, Hall SJ, Hall M, Herrera PC, Leventhal EA, Leventhal H, Diefenbach MA (2015) Decision-making processes among prostate cancer survivors with rising PSA levels: results from a qualitative analysis. Med Decis Mak 35(4):477–486. https://​doi.​org/​10.​1177/​0272989X14558424​CrossRef
14.
Zurück zum Zitat Rivas C, Matheson L, Nayoan J, Glaser A, Gavin A, Watson E, Wagland R (Submitted) Men’s transformations following a prostate cancer diagnosis and opportunities for intervention: a metaethnographic study Rivas C, Matheson L, Nayoan J, Glaser A, Gavin A, Watson E, Wagland R (Submitted) Men’s transformations following a prostate cancer diagnosis and opportunities for intervention: a metaethnographic study
22.
Zurück zum Zitat Downing A, Wright P, Wagland R, Watson E, Kearney T, Mottram R, Allen M, Cairnduff V, McSorley O, Butcher H, Hounsome L, Donnelly C, Selby P, Kind P, Cross W, Catto JW, Huws D, Brewster DH, McNair E, Matheson L, Rivas C, Nayoan J, Horton M, Corner J, Verne J, Gavin A, Glaser AW (2016) Life after prostate cancer diagnosis: protocol for a UK-wide patient-reported outcomes study. BMJ Open 6(12):e013555. https://doi.org/10.1136/bmjopen-2016-013555CrossRefPubMedPubMedCentral Downing A, Wright P, Wagland R, Watson E, Kearney T, Mottram R, Allen M, Cairnduff V, McSorley O, Butcher H, Hounsome L, Donnelly C, Selby P, Kind P, Cross W, Catto JW, Huws D, Brewster DH, McNair E, Matheson L, Rivas C, Nayoan J, Horton M, Corner J, Verne J, Gavin A, Glaser AW (2016) Life after prostate cancer diagnosis: protocol for a UK-wide patient-reported outcomes study. BMJ Open 6(12):e013555. https://​doi.​org/​10.​1136/​bmjopen-2016-013555CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Matheson L, Watson EK, Nayoan J, Wagland R, Glaser A, Gavin A, Wright P, Rivas C (2017) A qualitative metasynthesis exploring the impact of prostate cancer and its management on younger, unpartnered and gay men. Eur J Cancer Care 26(6). https://doi.org/10.1111/ecc.12676 Matheson L, Watson EK, Nayoan J, Wagland R, Glaser A, Gavin A, Wright P, Rivas C (2017) A qualitative metasynthesis exploring the impact of prostate cancer and its management on younger, unpartnered and gay men. Eur J Cancer Care 26(6). https://​doi.​org/​10.​1111/​ecc.​12676
26.
Zurück zum Zitat QSR International Pty Ltd (2016) NVivo qualitative data analysis Software: version 11 QSR International Pty Ltd (2016) NVivo qualitative data analysis Software: version 11
30.
Zurück zum Zitat Wright P, Wilding S, Watson E, Downing A, Selby P, Hounsome L, Wagland R, Brewster DH, Huws D, Butcher H, Mottram R, Kearney T, Allen M, Gavin A, Glaser A (2019) Key factors associated with social distress after prostate cancer: results from the United Kingdom Life after Prostate Cancer diagnosis study. Cancer Epidemiol 60:201–207. https://doi.org/10.1016/j.canep.2019.04.006CrossRefPubMed Wright P, Wilding S, Watson E, Downing A, Selby P, Hounsome L, Wagland R, Brewster DH, Huws D, Butcher H, Mottram R, Kearney T, Allen M, Gavin A, Glaser A (2019) Key factors associated with social distress after prostate cancer: results from the United Kingdom Life after Prostate Cancer diagnosis study. Cancer Epidemiol 60:201–207. https://​doi.​org/​10.​1016/​j.​canep.​2019.​04.​006CrossRefPubMed
33.
Zurück zum Zitat Wilding S, Downing A, Wright P, Selby P, Watson E, Wagland R, Donnelly D, Mason M, Henry A, Gavin A, Glaser AW (In preparation) Cancer-related symptoms, mental well-being and psychological distress in men diagnosed with prostate cancer treated with androgen deprivation therapy Wilding S, Downing A, Wright P, Selby P, Watson E, Wagland R, Donnelly D, Mason M, Henry A, Gavin A, Glaser AW (In preparation) Cancer-related symptoms, mental well-being and psychological distress in men diagnosed with prostate cancer treated with androgen deprivation therapy
34.
Zurück zum Zitat Downing A, Wright P, Hounsome L, Selby P, Wilding S, Watson E, Wagland R, Kind P, Donnelly D, Butcher H (2018) Quality of life in men living with advanced and localised prostate cancer: a United Kingdom population-wide patient-reported outcome study of 30,000 men. Lancet Oncol Downing A, Wright P, Hounsome L, Selby P, Wilding S, Watson E, Wagland R, Kind P, Donnelly D, Butcher H (2018) Quality of life in men living with advanced and localised prostate cancer: a United Kingdom population-wide patient-reported outcome study of 30,000 men. Lancet Oncol
35.
Zurück zum Zitat Antonovsky A (1979) Health, stress and coping. Jossey-Bass, San Fransisco Antonovsky A (1979) Health, stress and coping. Jossey-Bass, San Fransisco
37.
Zurück zum Zitat Antonovsky A (1987) Unraveling the mystery of health. How people manage stress and stay well. Jossey-Bass, San Fransisco, London Antonovsky A (1987) Unraveling the mystery of health. How people manage stress and stay well. Jossey-Bass, San Fransisco, London
38.
Zurück zum Zitat Mishel MH (1990) Reconceptualization of the uncertainty in illness theory. Image J Nurs Sch 22(4):256–262CrossRefPubMed Mishel MH (1990) Reconceptualization of the uncertainty in illness theory. Image J Nurs Sch 22(4):256–262CrossRefPubMed
43.
Zurück zum Zitat Courtenay WH (2000) Constructions of masculinity and their influence on men's well-being: a theory of gender and health. Soc Sci Med 50(10):1385–1401CrossRefPubMed Courtenay WH (2000) Constructions of masculinity and their influence on men's well-being: a theory of gender and health. Soc Sci Med 50(10):1385–1401CrossRefPubMed
Metadaten
Titel
Strategies for living well with hormone-responsive advanced prostate cancer—a qualitative exploration
verfasst von
Lauren Matheson
Jo Nayoan
Carol Rivas
Jo Brett
Penny Wright
Hugh Butcher
Paul Jordan
Anna Gavin
Adam Glaser
Malcolm Mason
Richard Wagland
Eila Watson
Publikationsdatum
06.07.2020
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 3/2021
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-020-05594-8

Weitere Artikel der Ausgabe 3/2021

Supportive Care in Cancer 3/2021 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.