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Current Neurology and Neuroscience Reports
Erschienen in:

11.09.2024 | Review

Subcortical Aphasia: An Update

verfasst von: Victor Nascimento Almeida, Marcia Radanovic

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 11/2024

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Abstract

Purpose of review

This review aims to rediscuss the leading theories concerning the role of basal ganglia and the thalamus in the genesis of aphasic symptoms in the absence of gross anatomical lesions in cortical language areas as assessed by conventional neuroimaging studies.

Recent findings

New concepts in language processing and modern neuroimaging techniques have enabled some progress in resolving the impasse between the current dominant theories: (a) direct and specific linguistic processing and (b) subcortical structures as processing relays in domain-general functions. Of particular interest are studies of connectivity based on functional magnetic resonance imaging (MRI) and tractography that highlight the impact of white matter pathway lesions on aphasia development and recovery.

Summary

Connectivity studies have put into evidence the central role of the arcuate fasciculus (AF), inferior frontal occipital fasciculus (IFOF), and uncinate fasciculus (UF) in the genesis of aphasia. Regarding the thalamus, its involvement in lexical-semantic processing through modulation of the frontal cortex is becoming increasingly apparent.
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Metadaten
Titel
Subcortical Aphasia: An Update
verfasst von
Victor Nascimento Almeida
Marcia Radanovic
Publikationsdatum
11.09.2024
Verlag
Springer US
Erschienen in
Current Neurology and Neuroscience Reports / Ausgabe 11/2024
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-024-01373-8

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