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Erschienen in: European Radiology 4/2018

13.11.2017 | Computed Tomography

Subtraction multiphase CT angiography: A new technique for faster detection of intracranial arterial occlusions

verfasst von: Danielle Byrne, John P. Walsh, Gavin Sugrue, Emma Stanley, Michael Marnane, Cathal D. Walsh, Peter Kelly, Sean Murphy, Eoin C. Kavanagh, Peter J. MacMahon

Erschienen in: European Radiology | Ausgabe 4/2018

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Abstract

Objective

To describe and evaluate a novel technical development to improve detection of intracranial vessel occlusions using multiphase CT angiography (MPCTA).

Materials and methods

The institutional ethics committee approved the study. Fifty patients (30 consecutive distal (M2 or smaller) anterior circulation occlusions, ten M1 occlusions, ten cases without occlusion) presenting with suspected AIS who underwent MPCTA were included. Post-processing of MPCTA studies created “subtraction” and “delayed enhancement” (DE) datasets. Initially, non-contrast CT and MPCTA studies for each patient were evaluated. Readers' confidence, speed and sensitivity of detection of intracranial vessel occlusions were recorded. After an interval of at least 4 weeks, readers were provided with post-processed images and studies were re-evaluated.

Results

While the sensitivity of detection of intracranial vessel occlusions was equal for both conventional MPCTA and subMPCTA, the mean time taken to identify a vessel occlusion decreased by 64 % using subMPCTA (16 s vs. 45 s with conventional MPCTA) (p<0.001). In addition, confidence in interpretation improved (from 4.4 to 4.9) using subMPCTA (p<0.001).

Conclusion

SubMPCTA is a novel technique that aids in identifying small intracranial vessel occlusions in the suspected AIS patient. SubMPCTA increases confidence in interpretation and reduces the time taken to detect intracranial vessel occlusions.

Key Points

• SubMPCTA processes MPCTA data to better demonstrate intracranial arterial occlusions.
• SubMPCTA increases confidence and speed of interpretation of MPCTA studies.
• SubMPCTA may aid in rapidly differentiating acute ischaemic stroke from stroke mimics.
Literatur
1.
Zurück zum Zitat Menon BK, d'Esterre CD, Qazi EM et al (2015) Multiphase CT Angiography: A New Tool for the Imaging Triage of Patients with Acute Ischemic Stroke. Radiology 275:510–520CrossRefPubMed Menon BK, d'Esterre CD, Qazi EM et al (2015) Multiphase CT Angiography: A New Tool for the Imaging Triage of Patients with Acute Ischemic Stroke. Radiology 275:510–520CrossRefPubMed
2.
Zurück zum Zitat Bang OY, Goyal M, Liebeskind DS (2015) Collateral Circulation in Ischemic Stroke: Assessment Tools and Therapeutic Strategies. Stroke 46:3302–3309CrossRefPubMedPubMedCentral Bang OY, Goyal M, Liebeskind DS (2015) Collateral Circulation in Ischemic Stroke: Assessment Tools and Therapeutic Strategies. Stroke 46:3302–3309CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Kucinski T, Koch C, Eckert B et al (2003) Collateral circulation is an independent radiological predictor of outcome after thrombolysis in acute ischaemic stroke. Neuroradiology 45:11–18CrossRefPubMed Kucinski T, Koch C, Eckert B et al (2003) Collateral circulation is an independent radiological predictor of outcome after thrombolysis in acute ischaemic stroke. Neuroradiology 45:11–18CrossRefPubMed
5.
Zurück zum Zitat Wahlgren N, Moreira T, Michel P et al (2016) Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN. Int J Stroke 11:134–147CrossRefPubMed Wahlgren N, Moreira T, Michel P et al (2016) Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN. Int J Stroke 11:134–147CrossRefPubMed
6.
Zurück zum Zitat Laurencin C, Philippeau F, Blanc-Lasserre K et al (2015) Thrombolysis for Acute Minor Stroke: Outcome and Barriers to Management. Results from the RESUVAL Stroke Network. Cerebrovasc Dis 40:3–9CrossRefPubMed Laurencin C, Philippeau F, Blanc-Lasserre K et al (2015) Thrombolysis for Acute Minor Stroke: Outcome and Barriers to Management. Results from the RESUVAL Stroke Network. Cerebrovasc Dis 40:3–9CrossRefPubMed
7.
Zurück zum Zitat Greisenegger S, Seyfang L, Kiechl S, Lang W, Ferrari J (2014) Thrombolysis in patients with mild stroke: results from the Austrian Stroke Unit Registry. Stroke 45:765–769CrossRefPubMed Greisenegger S, Seyfang L, Kiechl S, Lang W, Ferrari J (2014) Thrombolysis in patients with mild stroke: results from the Austrian Stroke Unit Registry. Stroke 45:765–769CrossRefPubMed
8.
Zurück zum Zitat Rha JH, Saver JL (2007) The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 38:967–973CrossRefPubMed Rha JH, Saver JL (2007) The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 38:967–973CrossRefPubMed
9.
Zurück zum Zitat Menon BK, Qazi E, Nambiar V et al (2015) Differential Effect of Baseline Computed Tomographic Angiography Collaterals on Clinical Outcome in Patients Enrolled in the Interventional Management of Stroke III Trial. Stroke 46:1239–1244CrossRefPubMedPubMedCentral Menon BK, Qazi E, Nambiar V et al (2015) Differential Effect of Baseline Computed Tomographic Angiography Collaterals on Clinical Outcome in Patients Enrolled in the Interventional Management of Stroke III Trial. Stroke 46:1239–1244CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat d'Esterre CD, Trivedi A, Pordeli P et al (2017) Regional Comparison of Multiphase Computed Tomographic Angiography and Computed Tomographic Perfusion for Prediction of Tissue Fate in Ischemic Stroke. Stroke 48:939–945CrossRefPubMed d'Esterre CD, Trivedi A, Pordeli P et al (2017) Regional Comparison of Multiphase Computed Tomographic Angiography and Computed Tomographic Perfusion for Prediction of Tissue Fate in Ischemic Stroke. Stroke 48:939–945CrossRefPubMed
13.
Zurück zum Zitat Kamal N, Hill MD, Blacquiere DP et al (2015) Rapid Assessment and Treatment of Transient Ischemic Attacks and Minor Stroke in Canadian Emergency Departments: Time for a Paradigm Shift. Stroke 46:2987–2990CrossRefPubMed Kamal N, Hill MD, Blacquiere DP et al (2015) Rapid Assessment and Treatment of Transient Ischemic Attacks and Minor Stroke in Canadian Emergency Departments: Time for a Paradigm Shift. Stroke 46:2987–2990CrossRefPubMed
14.
Zurück zum Zitat Poletti PA, Rosset A, Didier D et al (2004) Subtraction CT angiography of the lower limbs: a new technique for the evaluation of acute arterial occlusion. AJR Am J Roentgenol 183:1445–1448CrossRefPubMed Poletti PA, Rosset A, Didier D et al (2004) Subtraction CT angiography of the lower limbs: a new technique for the evaluation of acute arterial occlusion. AJR Am J Roentgenol 183:1445–1448CrossRefPubMed
15.
Zurück zum Zitat Tomandl BF, Hammen T, Klotz E, Ditt H, Stemper B, Lell M (2006) Bone-subtraction CT angiography for the evaluation of intracranial aneurysms. AJNR Am J Neuroradiol 27:55–59PubMed Tomandl BF, Hammen T, Klotz E, Ditt H, Stemper B, Lell M (2006) Bone-subtraction CT angiography for the evaluation of intracranial aneurysms. AJNR Am J Neuroradiol 27:55–59PubMed
16.
Zurück zum Zitat Jovin TG, Saver JL, Ribo M et al (2017) Diffusion-weighted imaging or computerized tomography perfusion assessment with clinical mismatch in the triage of wake up and late presenting strokes undergoing neurointervention with Trevo (DAWN) trial methods. Int J Stroke 12:641–652CrossRefPubMed Jovin TG, Saver JL, Ribo M et al (2017) Diffusion-weighted imaging or computerized tomography perfusion assessment with clinical mismatch in the triage of wake up and late presenting strokes undergoing neurointervention with Trevo (DAWN) trial methods. Int J Stroke 12:641–652CrossRefPubMed
17.
Zurück zum Zitat Demchuk AM, Menon BK, Goyal M (2016) Comparing Vessel Imaging: Noncontrast Computed Tomography/Computed Tomographic Angiography Should Be the New Minimum Standard in Acute Disabling Stroke. Stroke 47:273-281 Demchuk AM, Menon BK, Goyal M (2016) Comparing Vessel Imaging: Noncontrast Computed Tomography/Computed Tomographic Angiography Should Be the New Minimum Standard in Acute Disabling Stroke. Stroke 47:273-281
18.
Zurück zum Zitat Djulejic V, Marinkovic S, Georgievski B et al (2016) Clinical significance of blood supply to the internal capsule and basal ganglia. J Clin Neurosci 25:19–26CrossRefPubMed Djulejic V, Marinkovic S, Georgievski B et al (2016) Clinical significance of blood supply to the internal capsule and basal ganglia. J Clin Neurosci 25:19–26CrossRefPubMed
19.
Zurück zum Zitat Touaoussa A, El Youssi H, El Hassani I et al (2015) Disseminated intravascular coagulation: clinical and biological diagnosis. Ann Biol Clin (Paris) 73:657–663 Touaoussa A, El Youssi H, El Hassani I et al (2015) Disseminated intravascular coagulation: clinical and biological diagnosis. Ann Biol Clin (Paris) 73:657–663
Metadaten
Titel
Subtraction multiphase CT angiography: A new technique for faster detection of intracranial arterial occlusions
verfasst von
Danielle Byrne
John P. Walsh
Gavin Sugrue
Emma Stanley
Michael Marnane
Cathal D. Walsh
Peter Kelly
Sean Murphy
Eoin C. Kavanagh
Peter J. MacMahon
Publikationsdatum
13.11.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 4/2018
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-017-5124-1

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