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International Journal of Hematology
Erschienen in: International Journal of Hematology 5/2008

01.12.2008 | Case Report

Successful cord blood transplantation for mycosis fungoides

verfasst von: Takuya Fukushima, Kensuke Horio, Emi Matsuo, Daisuke Imanishi, Reishi Yamasaki, Hideki Tsushima, Yoshitaka Imaizumi, Koichi Ohshima, Tomoko Hata, Shinichiro Yoshida, Yasushi Miyazaki, Masao Tomonaga

Erschienen in: International Journal of Hematology | Ausgabe 5/2008

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Abstract

A 26-year-old female diagnosed as mycosis fungoides (MF, clinical stage IV) was treated with single-agent chemotherapy, multi-drug chemotherapy and unrelated bone marrow transplantation with reduced-intensity conditioning (engraftment failure), resulting in failure. Unrelated cord blood transplantation (CBT) as second transplantation following myeloablative conditioning brought complete remission (CR), but relapse of MF occurred 3 months after transplantation. However, discontinuation of immune suppressant led to the regression of MF regions and to second CR that continued for more than 23 months. This is the first report of successful CBT for MF, suggesting the graft-versus-MF effect in a setting of CBT.
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Metadaten
Titel
Successful cord blood transplantation for mycosis fungoides
verfasst von
Takuya Fukushima
Kensuke Horio
Emi Matsuo
Daisuke Imanishi
Reishi Yamasaki
Hideki Tsushima
Yoshitaka Imaizumi
Koichi Ohshima
Tomoko Hata
Shinichiro Yoshida
Yasushi Miyazaki
Masao Tomonaga
Publikationsdatum
01.12.2008
Verlag
Springer Japan
Erschienen in
International Journal of Hematology / Ausgabe 5/2008
Print ISSN: 0925-5710
Elektronische ISSN: 1865-3774
DOI
https://doi.org/10.1007/s12185-008-0190-4

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