Skip to main content
Erschienen in: CardioVascular and Interventional Radiology 7/2016

25.02.2016 | Case Report

Successful Preoperative Chemoembolization in the Treatment of a Giant Malignant Phyllodes Tumor

verfasst von: Kazuki Hashimoto, Hidefumi Mimura, Yasunori Arai, Masatomo Doi, Yasuyuki Kojima, Koichiro Tsugawa, Yasuo Nakajima

Erschienen in: CardioVascular and Interventional Radiology | Ausgabe 7/2016

Einloggen, um Zugang zu erhalten

Abstract

The malignant phyllodes tumor is a relatively rare neoplasm and has not previously been a therapeutic target of interventional radiology. Herein, we report a successful case of preoperative chemoembolization of a giant malignant phyllodes tumor. The objective was to achieve sufficient tumor shrinkage before surgery to avoid the requirement for skin grafting after resection. Intra-arterial epirubicin infusion and subsequent embolization with Embosphere Microspheres (BioSphere Medical, Rockland, MA, USA) was undertaken three times over the course of 6 weeks and was well tolerated. The patient underwent surgery without skin grafting. Neither local recurrence nor distant metastasis was observed at 6 months after surgery.
Literatur
1.
Zurück zum Zitat Reinfuss M, Mitus J, Duda K, Stelmach A, et al. The treatment and prognosis of patients with phyllodes tumor of the breast. Cancer. 1996;77:910–6.CrossRefPubMed Reinfuss M, Mitus J, Duda K, Stelmach A, et al. The treatment and prognosis of patients with phyllodes tumor of the breast. Cancer. 1996;77:910–6.CrossRefPubMed
2.
Zurück zum Zitat Kitagawa K, Yamakado K, Nakatsuka A, Tanaka N, Matsumura K, Takeda K, et al. Preoperative transcatheter arterial infusion chemotherapy for locally advanced breast cancer (stage IIIb) for down-staging and increase of resectability. Eur J Radiol. 2002;43(1):31–6.CrossRefPubMed Kitagawa K, Yamakado K, Nakatsuka A, Tanaka N, Matsumura K, Takeda K, et al. Preoperative transcatheter arterial infusion chemotherapy for locally advanced breast cancer (stage IIIb) for down-staging and increase of resectability. Eur J Radiol. 2002;43(1):31–6.CrossRefPubMed
3.
Zurück zum Zitat Koyama H, Wada T, Takahashi Y, Iwanaga T, Aoki Y. Intra-arterial infusion chemotherapy as preoperative treatment of locally advanced breast cancer. Cancer. 1975;48(6):1309–14. Koyama H, Wada T, Takahashi Y, Iwanaga T, Aoki Y. Intra-arterial infusion chemotherapy as preoperative treatment of locally advanced breast cancer. Cancer. 1975;48(6):1309–14.
4.
Zurück zum Zitat Takizawa K, Shimamoto H, Ogawa Y, Yoshimatsu M, Yagihashi K, Nakajima Y, et al. Development of a new subclavian arterial infusion chemotherapy method for locally or recurrent advanced breast cancer using an implanted catheter-port system after redistribution of arterial tumor supply. Cardiovasc Interv Radiol. 2009;32(5):1059–66.CrossRef Takizawa K, Shimamoto H, Ogawa Y, Yoshimatsu M, Yagihashi K, Nakajima Y, et al. Development of a new subclavian arterial infusion chemotherapy method for locally or recurrent advanced breast cancer using an implanted catheter-port system after redistribution of arterial tumor supply. Cardiovasc Interv Radiol. 2009;32(5):1059–66.CrossRef
5.
Zurück zum Zitat Lencioni R, De Baere T, Burrel M, Caridi JG, Lammer J, Malagari K, et al. Transcatheter treatment of hepatocellular carcinoma with doxorubicin-loaded dc bead (DEBDOX): technical recommendations. Cardiovasc Interv Radiol. 2012;35(5):980–5.CrossRef Lencioni R, De Baere T, Burrel M, Caridi JG, Lammer J, Malagari K, et al. Transcatheter treatment of hepatocellular carcinoma with doxorubicin-loaded dc bead (DEBDOX): technical recommendations. Cardiovasc Interv Radiol. 2012;35(5):980–5.CrossRef
6.
Zurück zum Zitat Jang JH, Choi M-Y, Lee SK, Kim S, Kim J, Lee J, et al. Clinicopathologic risk factors for the local recurrence of phyllodes tumors of the breast. Ann Surg Oncol. 2012;19(8):2612–7.CrossRefPubMed Jang JH, Choi M-Y, Lee SK, Kim S, Kim J, Lee J, et al. Clinicopathologic risk factors for the local recurrence of phyllodes tumors of the breast. Ann Surg Oncol. 2012;19(8):2612–7.CrossRefPubMed
7.
Zurück zum Zitat Cho E, Kim HS, Park YM, Lee JY, Kim HO. Cutaneous complications following transcatheter arterial chemoembolization. Int J Dermatol. 2013;52(11):1449–50.CrossRefPubMed Cho E, Kim HS, Park YM, Lee JY, Kim HO. Cutaneous complications following transcatheter arterial chemoembolization. Int J Dermatol. 2013;52(11):1449–50.CrossRefPubMed
8.
Zurück zum Zitat Patel K, Kimbrell BJ, Marx MV, Petrone P, Asensio JA. Angiographic embolization of an expanding breast hematoma after blunt trauma: a novel approach to a rare injury. J Trauma. 2009;67(1):E14–6.CrossRefPubMed Patel K, Kimbrell BJ, Marx MV, Petrone P, Asensio JA. Angiographic embolization of an expanding breast hematoma after blunt trauma: a novel approach to a rare injury. J Trauma. 2009;67(1):E14–6.CrossRefPubMed
Metadaten
Titel
Successful Preoperative Chemoembolization in the Treatment of a Giant Malignant Phyllodes Tumor
verfasst von
Kazuki Hashimoto
Hidefumi Mimura
Yasunori Arai
Masatomo Doi
Yasuyuki Kojima
Koichiro Tsugawa
Yasuo Nakajima
Publikationsdatum
25.02.2016
Verlag
Springer US
Erschienen in
CardioVascular and Interventional Radiology / Ausgabe 7/2016
Print ISSN: 0174-1551
Elektronische ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-016-1311-8

Weitere Artikel der Ausgabe 7/2016

CardioVascular and Interventional Radiology 7/2016 Zur Ausgabe

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.