Background
Methods
Disinfectants, bacterium, and surface used in study
Disinfectant Product “Name” (used throughout manuscript) a | Disinfectant Active Ingredient(s) | Label Contact Timeb |
---|---|---|
0.5% quat + 55% alcohol | - 0.25% n-alkyl dimethyl ethylbenzyl ammonium chlorides - 0.25% n-alkyl dimethyl benzyl ammonium chlorides - 55% isopropyl alcohol | 2 min |
0.76% quat + 22.5% alcohol | - 0.76% didecyldimethylammonium chlorides - 7.5% ethanol - 15% isopropyl alcohol | 1 min |
1.4% hydrogen peroxide | - 1.4% hydrogen peroxide | 1 min |
1.312% sodium hypochlorite | - 1.312% sodium hypochlorite | 1 min |
0.5% hydrogen peroxide | - 0.5% hydrogen peroxide | 1 min |
0.55% sodium hypochlorite | - 0.55% sodium hypochlorite | 30 s |
0.28% quat | - 0.14% n-alkyl dimethyl ethylbenzyl ammonium chlorides - 0.14% n-akyl dimethyl benzyl ammonium chlorides | 3 min |
0.21% quat | - 0.105% n-alkyl dimethyl ethylbenzyl ammonium chlorides - 0.105% n-alkyl dimethyl benzyl ammonium chlorides | 3 min |
0.61% quat + 56% alcohol | - 0.61% dodecyl dimethyl ammonium chloride - 27.3% ethyl alcohol - 28.7% isopropyl alcohol | 1 min |
0.308% quat + 21% alcohol | - 0.154% n-alkyl dimethyl benzyl ammonium chlorides - 0.154% n-alkyl ethylbenzyl ammonium chlorides - 21.000% isopropyl alcohol | 2 min |
Towelette disinfectant load and surface coverage measurements
Towelette bactericidal efficacy
Statistical analyses
Results
Disinfectant product, surface area wiped, and strain significantly impacted bactericidal efficacy
Bactericidal efficacy varied between P. aeruginosa and S. aureus by disinfectant
Percent of liquid released per ft2 from towelettes decreased as area wiped increased and varied among disinfectant products
Average liquid released per ft2 Average liquid released (g/ft2)a | ||||||||
---|---|---|---|---|---|---|---|---|
Towelette Product | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
0.55% sodium hypochlorite | 0.51 ± 0.09 | 0.43 ± 0.08 | 0.40 ± 0.14 | 0.40 ± 0.07 | 0.34 ± 0.09 | 0.32 ± 0.08 | 0.37 ± 0.06 | 0.36 ± 0.05 |
0.5% quat + 55% alcohol | 0.72 ± 0.54 | 0.38 ± 0.52 | 0.35 ± 0.04 | 0.29 ± 0.09 | 0.27 ± 0.02 | 0.24 ± 0.02 | 0.25 ± 0.06 | 0.22 ± 0.04 |
PBS-wetted towelettes | 0.27 ± 0.06 | 0.22 ± 0.05 | 0.22 ± 0.08 | 0.20 ± 0.04 | 0.18 ± 0.03 | 0.17 ± 0.03 | 0.16 ± 0.03 | 0.16 ± 0.03 |
1.312% sodium hypochlorite | 0.16 ± 0.16 | 0.33 ± 0.06 | 0.33 ± 0.03 | 0.27 ± 0.06 | 0.28 ± 0.03 | 0.25 ± 0.02 | 0.23 ± 0.01 | 0.21 ± 0.04 |
1.4% hydrogen peroxide | 0.40 ± 0.21 | 0.26 ± 0.06 | 0.30 ± 0.01 | 0.21 ± 0.04 | 0.20 ± 0.03 | 0.20 ± 0.02 | 0.19 ± 0.03 | 0.18 ± 0.03 |
0.5% hydrogen peroxide | 0.36 ± 0.12 | 0.26 ± 0.07 | 0.26 ± 0.05 | 0.22 ± 0.04 | 0.21 ± 0.04 | 0.19 ± 0.04 | 0.18 ± 0.03 | 0.17 ± 0.02 |
0.21% quat | 0.32 ± 0.08 | 0.22 ± 0.05 | 0.22 ± 0.05 | 0.21 ± 0.06 | 0.21 ± 0.04 | 0.18 ± 0.03 | 0.17 ± 0.04 | 0.16 ± 0.05 |
0.28% quat | 0.35 ± 0.12 | 0.24 ± 0.01 | 0.25 ± 0.06 | 0.19 ± 0.06 | 0.17 ± 0.03 | 0.16 ± 0.01 | 0.16 ± 0.02 | 0.16 ± 0.03 |
0.76% quat + 22.5% alcohol | 0.50 ± 0.12 | 0.31 ± 0.04 | 0.27 ± 0.04 | 0.23 ± 0.03 | 0.22 ± 0.02 | 0.21 ± 0.03 | 0.20 ± 0.02 | 0.19 ± 0.02 |
0.308% quat + 21% alcohol | 0.25 ± 0.03 | 0.19 ± 0.02 | 0.17 ± 0.01 | 0.16 ± 0.01 | 0.15 ± 0.01 | 0.14 ± 0.01 | 0.13 ± 0.01 | 0.14 ± 0.01 |
0.61% quat + 56% alcohol | 0.72 ± 0.39 | 0.32 ± 0.09 | 0.27 ± 0.09 | 0.19 ± 0.04 | 0.18 ± 0.04 | 0.16 ± 0.01 | 0.15 ± 0.01 | 0.15 ± 0.05 |