Surgery combined endoscopic stricturotomy for deep small bowel strictures from Crohn’ disease: a prospective, single-center cohort study of a novel approach
- 27.05.2025
Erschienen in:
- Verfasst von
- Bo Peng
- Zhongcheng Liu
- Biyao Wang
- Jia Ke
- Qin Guo
- Erschienen in
- Surgical Endoscopy | Ausgabe 7/2025
Abstract
Background and aims
A common complication which can influence the prognosis of Crohn’s disease (CD) is multi-segmental strictures, and there are limitations to using either surgical or endoscopic treatment alone. We aimed to treat multi-segmental strictures in CD using combination of surgery and endoscopic therapy and to evaluate the efficacy and safety of conventional surgery combined with endoscopic stricturotomy for the treatment of deep small bowel multi-segmental fibrotic strictures.
Methods
21 patients with CD who underwent conventional surgery combined with endoscopic stricturotomy between January 2020 and December 2023 were included. Outcomes included immediate technical success, short- and long-term clinical efficacy, risk factors assessment, and analysis of adverse events. No risk factors were identified that would predict re-intervention.
Results
The overall immediate success rate of the combined technique was 100%, with a 98.4% success rate for the endoscopic procedure alone. 85.7% of patients showed significant improvement in obstructive symptoms compared to the previous period, and only 9.5% required enteral nutrition, with the remainder resuming a regular diet by 8 weeks (all P < 0.0001). The median follow-up of the 21 patients was 528 days (IQR, 404–1296), with a one-year no re-intervention rate of 81.7% (95% CI, 70.6–90.2%). The incidence of adverse events of the procedure was 19%, 14% bleeding and 5% perforation, but all could be managed with intraoperative interventions without the need for postoperative re-intervention.
Conclusions
Surgery combined with endoscopic stricturotomy is a safe and effective treatment of multi-segmental fibrotic strictures in CD may provide a novel treatment option for strictures in CD.
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- Titel
- Surgery combined endoscopic stricturotomy for deep small bowel strictures from Crohn’ disease: a prospective, single-center cohort study of a novel approach
- Verfasst von
-
Bo Peng
Zhongcheng Liu
Biyao Wang
Jia Ke
Qin Guo
- Publikationsdatum
- 27.05.2025
- Verlag
- Springer US
- Erschienen in
-
Surgical Endoscopy / Ausgabe 7/2025
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218 - DOI
- https://doi.org/10.1007/s00464-025-11784-4
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