Skip to main content
Erschienen in: World Journal of Surgery 7/2019

19.02.2019 | Surgery in Low and Middle Income Countries

Surgical Considerations for Pediatric Snake Bites in Low- and Middle-Income Countries

verfasst von: Matthew C. Hernandez, Michael Traynor, John L. Bruce, Wanda Bekker, Grant L. Laing, Johnathon M. Aho, Victor Y. Kong, Denise B. Klinkner, Martin D. Zielinski, Damian L. Clarke

Erschienen in: World Journal of Surgery | Ausgabe 7/2019

Einloggen, um Zugang zu erhalten

Abstract

Background

Snake envenomation is associated with major morbidity especially in low- and middle-income countries and may require fasciotomy. We determined patient factors associated with the need for fasciotomy after venomous snake bites in children located in KwaZulu-Natal, South Africa.

Methods

Single institutional review of historical data (2012–2017) for children (<18 years) sustaining snake envenomation was performed. Clinical data, management, and outcomes were abstracted. Syndromes after snake bite were classified according to Blaylock nomenclature: progressive painful swelling (PPS), progressive weakness (PW), or bleeding (B), as it is difficult to reliably identify the species of snake after a bite. Comparative and multivariable analyses to determine factors associated with fasciotomy were performed.

Results

There were 72 children; mean age was 7 (±3) years, 59% male. Feet were most commonly affected (n = 27, 38%) followed by legs (n = 18, 25%). Syndromes (according to Blaylock) included PPS (n = 63, 88%), PW (n = 5, 7%), and B (n = 4, 5%). Eighteen patients underwent fasciotomy, and one required above knee amputation. Nine patients received anti-venom. Few patients (15%) received prophylactic beta-lactam antibiotics. Hemoglobin < 11 mg/dL, leukocytosis, INR >1.2, and age-adjusted shock index were associated with fasciotomy. On regression, age-adjusted shock index and hemoglobin concentration < 11 mg/dL, presentation >24 h after snake bite, and INR >1.2 were independently associated with fasciotomy. Model sensitivity was 0.89 and demonstrated good fit.

Conclusions

Patient factors were associated with the fasciotomy. These factors, coupled with clinical examination, may identify those who need early operative intervention. Improving time to treatment and the appropriate administration of anti-venom will minimize the need for surgery.

Level of evidence

III
Literatur
2.
Zurück zum Zitat Deribew A, Kebede B, Tessema GA, Adama YA, Misganaw A, Gebre T et al (2017) Mortality and disability-adjusted life-years (Dalys) for common neglected tropical diseases in Ethiopia, 1990–2015: evidence from the Global Burden of Disease Study 2015. Ethiop Med J 55(Suppl 1):3–14PubMedPubMedCentral Deribew A, Kebede B, Tessema GA, Adama YA, Misganaw A, Gebre T et al (2017) Mortality and disability-adjusted life-years (Dalys) for common neglected tropical diseases in Ethiopia, 1990–2015: evidence from the Global Burden of Disease Study 2015. Ethiop Med J 55(Suppl 1):3–14PubMedPubMedCentral
4.
Zurück zum Zitat Habib AG, Kuznik A, Hamza M, Abdullahi MI, Chedi BA, Chippaux JP et al (2015) Snakebite is under appreciated: appraisal of burden from West Africa. PLoS Negl Trop Dis 9(9):4–11CrossRef Habib AG, Kuznik A, Hamza M, Abdullahi MI, Chedi BA, Chippaux JP et al (2015) Snakebite is under appreciated: appraisal of burden from West Africa. PLoS Negl Trop Dis 9(9):4–11CrossRef
5.
Zurück zum Zitat Gutiérrez JM, Calvete JJ, Habib AG, Harrison RA, Williams DJ, Warrell DA (2017) Snakebite envenoming. Nat Rev Dis Prim 3:17063CrossRefPubMed Gutiérrez JM, Calvete JJ, Habib AG, Harrison RA, Williams DJ, Warrell DA (2017) Snakebite envenoming. Nat Rev Dis Prim 3:17063CrossRefPubMed
7.
Zurück zum Zitat Jorge MT, Ribeiro LA, O’Connell JL (1999) Prognostic factors for amputation in the case of envenoming by snakes of the Bothrops genus (Viperidae). Ann Trop Med Parasitol 93(4):401–408CrossRefPubMed Jorge MT, Ribeiro LA, O’Connell JL (1999) Prognostic factors for amputation in the case of envenoming by snakes of the Bothrops genus (Viperidae). Ann Trop Med Parasitol 93(4):401–408CrossRefPubMed
8.
Zurück zum Zitat Abubakar SB, Habib AGMJ (2010) Amputation and disability following snakebite in Nigeria. Trop Doct 40(2):114–116CrossRefPubMed Abubakar SB, Habib AGMJ (2010) Amputation and disability following snakebite in Nigeria. Trop Doct 40(2):114–116CrossRefPubMed
12.
Zurück zum Zitat Darryl W, Sartorius B, Hift R (2016) Estimating the burden of snakebite on public hospitals in KwaZulu Natal, South Africa. Wilderness Environ Med 27(1):53–61CrossRefPubMed Darryl W, Sartorius B, Hift R (2016) Estimating the burden of snakebite on public hospitals in KwaZulu Natal, South Africa. Wilderness Environ Med 27(1):53–61CrossRefPubMed
13.
Zurück zum Zitat Wood D, Webb CDJ (2009) Severe snakebites in northern KwaZulu-Natal: treatment modalities and outcomes. S Afr Med J 99(11):814–818PubMed Wood D, Webb CDJ (2009) Severe snakebites in northern KwaZulu-Natal: treatment modalities and outcomes. S Afr Med J 99(11):814–818PubMed
14.
Zurück zum Zitat Blaylock R (2004) Epidemiology of snakebite in Eshowe, KwaZulu-Natal, South Africa. Toxicon 43(2):159–166CrossRefPubMed Blaylock R (2004) Epidemiology of snakebite in Eshowe, KwaZulu-Natal, South Africa. Toxicon 43(2):159–166CrossRefPubMed
15.
Zurück zum Zitat Wood D, Sartorius BHR (2016) Classifying snakebite in South Africa: validating a scoring system. S Afr Med J 107(1):46–51CrossRefPubMed Wood D, Sartorius BHR (2016) Classifying snakebite in South Africa: validating a scoring system. S Afr Med J 107(1):46–51CrossRefPubMed
17.
Zurück zum Zitat Laing G, Bruce J, Skinner D, Allorto N, Aldous C, Thomson S (2015) Using a hybrid electronic medical record system for the surveillance of adverse surgical events and human error in a developing world surgical service 70–79 Laing G, Bruce J, Skinner D, Allorto N, Aldous C, Thomson S (2015) Using a hybrid electronic medical record system for the surveillance of adverse surgical events and human error in a developing world surgical service 70–79
18.
Zurück zum Zitat Manchev V, Bruce JL, Oosthuizen GV, Laing GL, Clarke DL (2015) The incidence, spectrum and outcome of paediatric trauma managed by the Pietermaritzburg Metropolitan Trauma Service. Ann R Coll Surg Engl 97(4):274–278CrossRefPubMedPubMedCentral Manchev V, Bruce JL, Oosthuizen GV, Laing GL, Clarke DL (2015) The incidence, spectrum and outcome of paediatric trauma managed by the Pietermaritzburg Metropolitan Trauma Service. Ann R Coll Surg Engl 97(4):274–278CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Rs B (1995) Retrospective analysis of snakebite at a rural hospital in Zululand. S Afr Med J 85(4):286 Rs B (1995) Retrospective analysis of snakebite at a rural hospital in Zululand. S Afr Med J 85(4):286
21.
Zurück zum Zitat Rs B (2005) The identification and syndromic management of snakebite in South Africa. S A Fam Pr 47(9):48–53 Rs B (2005) The identification and syndromic management of snakebite in South Africa. S A Fam Pr 47(9):48–53
22.
Zurück zum Zitat Blaylock R (2003) Femoral vessel entrapment and compartment syndromes following snakebite. S Afr Med J 41(3):72–73 Blaylock R (2003) Femoral vessel entrapment and compartment syndromes following snakebite. S Afr Med J 41(3):72–73
23.
Zurück zum Zitat Bae DS, Kadiyala RK, Waters PM (2001) Acute compartment syndrome in children: contemporary diagnosis, treatment, and outcome. J Pediatr Orthop 21(5):680–688 Bae DS, Kadiyala RK, Waters PM (2001) Acute compartment syndrome in children: contemporary diagnosis, treatment, and outcome. J Pediatr Orthop 21(5):680–688
24.
Zurück zum Zitat Sans M (2015) Snake bite—The neglected tropical disease. Lancet 386(9999):1110 Sans M (2015) Snake bite—The neglected tropical disease. Lancet 386(9999):1110
25.
Zurück zum Zitat Wood D, Sartorius B, Hift R (2016) Ultrasound findings in 42 patients with cytotoxic tissue damage following bites by South African snakes. Emerg Med J 33(7):477–481CrossRefPubMed Wood D, Sartorius B, Hift R (2016) Ultrasound findings in 42 patients with cytotoxic tissue damage following bites by South African snakes. Emerg Med J 33(7):477–481CrossRefPubMed
27.
Zurück zum Zitat Hon KL, Chow CM, Cheung KLLT (2005) Snakebite in a child: could we avoid the anaphylaxis or the fasciotomies? Ann Acad Med Singapore 34(7):454–456PubMed Hon KL, Chow CM, Cheung KLLT (2005) Snakebite in a child: could we avoid the anaphylaxis or the fasciotomies? Ann Acad Med Singapore 34(7):454–456PubMed
29.
Zurück zum Zitat Pattinson JP, Kong VY, Bruce JL, Oosthuizen GV, Bekker W, Laing GL, Wood D, Brysiewicz PCD (2017) Defining the need for surgical intervention following a snakebite still relies heavily on clinical assessment: the experience in Pietermaritzburg, South Africa. S Afr Med J. 107(12):1082–1085CrossRefPubMed Pattinson JP, Kong VY, Bruce JL, Oosthuizen GV, Bekker W, Laing GL, Wood D, Brysiewicz PCD (2017) Defining the need for surgical intervention following a snakebite still relies heavily on clinical assessment: the experience in Pietermaritzburg, South Africa. S Afr Med J. 107(12):1082–1085CrossRefPubMed
30.
Zurück zum Zitat Blaylock R (1991) Time of onset of clinical envenomation following snakebite in southern Africa. S Afr Med J 80(5):253PubMed Blaylock R (1991) Time of onset of clinical envenomation following snakebite in southern Africa. S Afr Med J 80(5):253PubMed
31.
Zurück zum Zitat Sharma SK, Chappuis F, Jha N, Bovier PA, Loutan LKS (2004) Impact of snake bites and determinants of fatal outcomes in southeastern Nepal. Am J Trop Med Hyg 71(2):234–238CrossRefPubMed Sharma SK, Chappuis F, Jha N, Bovier PA, Loutan LKS (2004) Impact of snake bites and determinants of fatal outcomes in southeastern Nepal. Am J Trop Med Hyg 71(2):234–238CrossRefPubMed
Metadaten
Titel
Surgical Considerations for Pediatric Snake Bites in Low- and Middle-Income Countries
verfasst von
Matthew C. Hernandez
Michael Traynor
John L. Bruce
Wanda Bekker
Grant L. Laing
Johnathon M. Aho
Victor Y. Kong
Denise B. Klinkner
Martin D. Zielinski
Damian L. Clarke
Publikationsdatum
19.02.2019
Verlag
Springer International Publishing
Erschienen in
World Journal of Surgery / Ausgabe 7/2019
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-019-04953-9

Weitere Artikel der Ausgabe 7/2019

World Journal of Surgery 7/2019 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.